| Min Pa: | Min Pa(max): | Activity's type: |
| Ext | Pa | Pi | Pmax | Activity | Other Results | ID Pa_max |
|---|---|---|---|---|---|---|
| 0.994 | 0 | 0.994 | Dipeptidyl peptidase IV inhibitor | 0.926 0.001 DBMET02383 0.869 0.001 DBMET02386 0.939 0.001 DBMET02387 0.67 0.001 DBMET02388 0.945 0.001 DBMET02394 0.573 0.001 DBMET02384 0.592 0.001 DBMET02385 0.573 0.001 DBMET02389 0.277 0.002 DBMET02390 0.144 0.004 DBMET02391 0.114 0.005 DBMET02392 0.205 0.003 DBMET02393 | ||
| 0.989 | 0.001 | 0.989 | Dipeptidyl peptidase inhibitor | 0.88 0.001 DBMET02383 0.783 0.001 DBMET02386 0.889 0.001 DBMET02387 0.582 0.002 DBMET02388 0.903 0.001 DBMET02394 0.467 0.002 DBMET02384 0.484 0.002 DBMET02385 0.493 0.002 DBMET02389 0.234 0.003 DBMET02390 0.124 0.005 DBMET02391 0.105 0.008 DBMET02392 0.181 0.004 DBMET02393 | ||
| 0.829 | 0.005 | 0.829 | Cyclophilin D inhibitor | 0.753 0.009 DBMET02383 0.738 0.011 DBMET02386 0.822 0.005 DBMET02387 0.725 0.012 DBMET02388 0.775 0.008 DBMET02394 0.643 0.021 DBMET02384 0.61 0.026 DBMET02385 0.808 0.006 DBMET02389 0.712 0.013 DBMET02390 0.74 0.01 DBMET02391 0.62 0.024 DBMET02392 0.715 0.013 DBMET02393 | ||
| 0.415 | 0.005 | 0.491 | Acetylcholine M1 receptor antagonist | 0.394 0.006 DBMET02383 0.334 0.01 DBMET02386 0.366 0.007 DBMET02387 0.29 0.016 DBMET02388 0.285 0.017 DBMET02394 0.315 0.012 DBMET02384 0.283 0.018 DBMET02385 0.491 0.004 DBMET02389 0.4 0.005 DBMET02390 0.152 0.073 DBMET02391 0.167 0.061 DBMET02392 0.193 0.045 DBMET02393 | DBMET02389 | |
| 0.384 | 0.031 | 0.384 | HERG channel blocker | 0.276 0.056 DBMET02383 0.262 0.061 DBMET02386 0.18 0.103 DBMET02387 0.197 0.092 DBMET02388 0.244 0.069 DBMET02394 0.175 0.106 DBMET02384 0.205 0.088 DBMET02389 0.149 0.132 DBMET02390 | ||
| 0.381 | 0.031 | 0.403 | Hypoglycemic | 0.32 0.046 DBMET02383 0.24 0.083 DBMET02386 0.403 0.027 DBMET02387 0.32 0.046 DBMET02388 0.38 0.031 DBMET02394 0.193 0.12 DBMET02384 0.263 0.069 DBMET02385 0.388 0.029 DBMET02389 0.238 0.084 DBMET02390 0.362 0.035 DBMET02391 0.255 0.074 DBMET02392 0.324 0.045 DBMET02393 | DBMET02387 | |
| 0.301 | 0.005 | 0.386 | Adenosine A2a receptor antagonist | 0.259 0.007 DBMET02383 0.264 0.007 DBMET02386 0.134 0.017 DBMET02387 0.279 0.006 DBMET02388 0.302 0.005 DBMET02394 0.223 0.009 DBMET02384 0.204 0.01 DBMET02385 0.386 0.004 DBMET02389 0.35 0.004 DBMET02390 0.185 0.011 DBMET02391 0.187 0.011 DBMET02392 0.277 0.006 DBMET02393 | DBMET02389 | |
| 0.294 | 0.005 | 0.361 | Adenosine A2 receptor antagonist | 0.273 0.006 DBMET02383 0.254 0.007 DBMET02386 0.127 0.02 DBMET02387 0.275 0.006 DBMET02388 0.305 0.005 DBMET02394 0.234 0.008 DBMET02384 0.204 0.01 DBMET02385 0.361 0.004 DBMET02389 0.33 0.005 DBMET02390 0.182 0.012 DBMET02391 0.194 0.011 DBMET02392 0.275 0.006 DBMET02393 | DBMET02389 | |
| 0.336 | 0.065 | 0.392 | Immunomodulator | 0.285 0.091 DBMET02383 0.363 0.055 DBMET02386 0.283 0.092 DBMET02387 0.392 0.046 DBMET02394 0.311 0.076 DBMET02384 0.284 0.091 DBMET02389 0.309 0.077 DBMET02390 0.315 0.074 DBMET02391 0.223 0.139 DBMET02392 0.318 0.073 DBMET02393 | DBMET02394 | |
| 0.326 | 0.084 | 0.603 | Vasodilator, peripheral | 0.396 0.057 DBMET02383 0.2 0.176 DBMET02386 0.216 0.158 DBMET02387 0.435 0.045 DBMET02388 0.245 0.131 DBMET02394 0.256 0.123 DBMET02384 0.51 0.026 DBMET02385 0.52 0.024 DBMET02389 0.361 0.069 DBMET02390 0.603 0.016 DBMET02391 0.423 0.048 DBMET02392 0.52 0.024 DBMET02393 | DBMET02391 | |
| 0.28 | 0.056 | 0.28 | Potassium channel (Voltage-sensitive) blocker | 0.202 0.095 DBMET02383 0.183 0.108 DBMET02386 0.256 0.064 DBMET02388 0.19 0.103 DBMET02394 0.154 0.133 DBMET02389 | ||
| 0.22 | 0.01 | 0.298 | Adenosine A1 receptor antagonist | 0.173 0.013 DBMET02383 0.257 0.008 DBMET02386 0.111 0.021 DBMET02387 0.182 0.013 DBMET02388 0.218 0.01 DBMET02394 0.208 0.01 DBMET02384 0.136 0.017 DBMET02385 0.255 0.008 DBMET02389 0.298 0.006 DBMET02390 0.128 0.018 DBMET02391 0.135 0.018 DBMET02392 0.211 0.01 DBMET02393 | DBMET02390 | |
| 0.287 | 0.119 | 0.331 | Toll-Like receptor agonist | 0.267 0.133 DBMET02383 0.305 0.108 DBMET02386 0.223 0.176 DBMET02387 0.283 0.122 DBMET02384 0.291 0.116 DBMET02389 0.305 0.108 DBMET02390 0.268 0.133 DBMET02391 0.331 0.092 DBMET02393 | DBMET02393 | |
| 0.197 | 0.036 | 0.198 | MAP kinase kinase 5 inhibitor | 0.198 0.034 DBMET02386 0.172 0.082 DBMET02387 0.151 0.149 DBMET02394 | DBMET02386 | |
| 0.195 | 0.038 | 0.29 | Insulin secretagoues | 0.153 0.072 DBMET02383 0.199 0.037 DBMET02387 0.184 0.045 DBMET02388 0.167 0.058 DBMET02394 0.121 0.109 DBMET02385 0.215 0.029 DBMET02389 0.289 0.014 DBMET02391 0.208 0.032 DBMET02392 0.29 0.014 DBMET02393 | DBMET02393 | |
| 0.178 | 0.042 | 0.297 | Phosphodiesterase inhibitor | 0.165 0.049 DBMET02383 0.161 0.052 DBMET02386 0.129 0.074 DBMET02387 0.266 0.019 DBMET02388 0.17 0.046 DBMET02394 0.147 0.06 DBMET02384 0.297 0.015 DBMET02389 0.282 0.017 DBMET02390 0.115 0.088 DBMET02393 | DBMET02389 | |
| 0.216 | 0.083 | 0.487 | Cyclic AMP phosphodiesterase inhibitor | 0.185 0.106 DBMET02383 0.233 0.072 DBMET02386 0.326 0.032 DBMET02388 0.195 0.097 DBMET02394 0.202 0.092 DBMET02384 0.475 0.008 DBMET02389 0.487 0.007 DBMET02390 0.256 0.061 DBMET02391 0.217 0.082 DBMET02392 0.252 0.063 DBMET02393 | DBMET02390 | |
| 0.135 | 0.014 | 0.19 | Phosphodiesterase 5A inhibitor | 0.128 0.016 DBMET02383 0.131 0.015 DBMET02386 0.151 0.01 DBMET02387 0.19 0.006 DBMET02388 0.143 0.012 DBMET02394 0.123 0.018 DBMET02384 0.092 0.031 DBMET02385 0.148 0.011 DBMET02389 0.147 0.011 DBMET02390 0.077 0.043 DBMET02391 0.075 0.045 DBMET02392 0.103 0.025 DBMET02393 | DBMET02388 | |
| 0.141 | 0.024 | 0.173 | Acetylcholine M3 receptor agonist | 0.133 0.028 DBMET02383 0.152 0.019 DBMET02386 0.124 0.033 DBMET02387 0.149 0.02 DBMET02388 0.135 0.027 DBMET02394 0.146 0.022 DBMET02384 0.109 0.04 DBMET02385 0.164 0.013 DBMET02389 0.173 0.009 DBMET02390 0.09 0.051 DBMET02391 0.085 0.056 DBMET02392 0.1 0.045 DBMET02393 | DBMET02390 | |
| 0.129 | 0.015 | 0.182 | Phosphodiesterase V inhibitor | 0.122 0.018 DBMET02383 0.124 0.017 DBMET02386 0.143 0.012 DBMET02387 0.182 0.007 DBMET02388 0.137 0.013 DBMET02394 0.118 0.02 DBMET02384 0.088 0.034 DBMET02385 0.142 0.012 DBMET02389 0.141 0.013 DBMET02390 0.073 0.048 DBMET02391 0.071 0.05 DBMET02392 0.099 0.028 DBMET02393 | DBMET02388 | |
| 0.25 | 0.148 | 0.268 | Toll-Like receptor 7 agonist | 0.232 0.165 DBMET02383 0.266 0.134 DBMET02386 0.246 0.151 DBMET02384 0.257 0.142 DBMET02389 0.268 0.132 DBMET02390 0.206 0.193 DBMET02391 0.264 0.136 DBMET02393 | DBMET02390 | |
| 0.144 | 0.047 | 0.216 | Acetylcholine muscarinic antagonist | 0.147 0.045 DBMET02383 0.113 0.075 DBMET02386 0.118 0.069 DBMET02387 0.115 0.072 DBMET02384 0.107 0.082 DBMET02385 0.216 0.021 DBMET02389 0.168 0.035 DBMET02390 | DBMET02389 | |
| 0.222 | 0.127 | 0.562 | Hypoxia-inducible factor 1 alpha inhibitor | 0.33 0.053 DBMET02386 0.365 0.04 DBMET02388 0.222 0.127 DBMET02394 0.215 0.135 DBMET02384 0.433 0.023 DBMET02389 0.562 0.009 DBMET02390 0.223 0.125 DBMET02391 0.267 0.086 DBMET02392 0.298 0.067 DBMET02393 | DBMET02390 | |
| 0.131 | 0.039 | 0.244 | Bronchodilator | 0.125 0.042 DBMET02383 0.109 0.054 DBMET02386 0.099 0.065 DBMET02387 0.161 0.028 DBMET02388 0.133 0.038 DBMET02394 0.107 0.056 DBMET02384 0.131 0.039 DBMET02385 0.244 0.013 DBMET02389 0.21 0.017 DBMET02390 0.163 0.027 DBMET02391 0.162 0.028 DBMET02392 0.18 0.022 DBMET02393 | DBMET02389 | |
| 0.118 | 0.039 | 0.118 | Phosphodiesterase 7B inhibitor | 0.09 0.069 DBMET02383 0.114 0.042 DBMET02386 0.103 0.053 DBMET02387 0.1 0.056 DBMET02388 0.109 0.047 DBMET02394 0.088 0.074 DBMET02384 0.094 0.065 DBMET02389 0.095 0.063 DBMET02390 | ||
| 0.182 | 0.113 | 0.189 | ErbB-1 antagonist | 0.173 0.128 DBMET02383 0.163 0.147 DBMET02387 0.189 0.102 DBMET02388 0.179 0.118 DBMET02394 0.16 0.154 DBMET02385 0.177 0.121 DBMET02389 0.18 0.116 DBMET02391 0.174 0.126 DBMET02392 0.185 0.108 DBMET02393 | DBMET02388 | |
| 0.087 | 0.03 | 0.119 | Phosphodiesterase III inhibitor | 0.087 0.03 DBMET02383 0.087 0.03 DBMET02386 0.111 0.018 DBMET02388 0.086 0.03 DBMET02394 0.086 0.03 DBMET02384 0.118 0.016 DBMET02389 0.119 0.015 DBMET02390 0.066 0.047 DBMET02391 0.071 0.042 DBMET02392 0.088 0.029 DBMET02393 | DBMET02390 | |
| 0.07 | 0.018 | 0.073 | Adenosine A2b receptor antagonist | 0.073 0.017 DBMET02383 0.054 0.029 DBMET02386 0.062 0.023 DBMET02388 0.058 0.026 DBMET02394 0.059 0.025 DBMET02384 0.053 0.03 DBMET02385 0.07 0.018 DBMET02389 0.062 0.022 DBMET02390 0.051 0.033 DBMET02392 0.069 0.018 DBMET02393 | DBMET02383 | |
| 0.077 | 0.026 | 0.077 | 5 Hydroxytryptamine 3 antagonist | 0.063 0.033 DBMET02383 0.058 0.038 DBMET02388 0.062 0.034 DBMET02394 | ||
| 0.097 | 0.049 | 0.195 | Phosphodiesterase I inhibitor | 0.081 0.075 DBMET02383 0.092 0.055 DBMET02386 0.187 0.012 DBMET02388 0.088 0.063 DBMET02394 0.137 0.02 DBMET02389 0.134 0.021 DBMET02390 0.114 0.03 DBMET02391 0.144 0.019 DBMET02392 0.195 0.011 DBMET02393 | DBMET02393 | |
| 0.071 | 0.026 | 0.093 | Phosphodiesterase 4C inhibitor | 0.067 0.029 DBMET02383 0.057 0.037 DBMET02386 0.057 0.037 DBMET02387 0.085 0.019 DBMET02388 0.07 0.026 DBMET02394 0.053 0.041 DBMET02384 0.093 0.016 DBMET02389 0.079 0.021 DBMET02390 | DBMET02389 | |
| 0.079 | 0.036 | 0.079 | Phosphodiesterase VIII inhibitor | 0.075 0.044 DBMET02386 0.068 0.06 DBMET02387 0.073 0.046 DBMET02388 0.076 0.042 DBMET02394 0.076 0.041 DBMET02389 0.074 0.044 DBMET02390 | ||
| 0.115 | 0.079 | 0.158 | Cholinergic antagonist | 0.117 0.076 DBMET02383 0.106 0.088 DBMET02386 0.108 0.085 DBMET02384 0.158 0.048 DBMET02389 0.152 0.052 DBMET02390 | DBMET02389 | |
| 0.076 | 0.042 | 0.076 | Toll-Like receptor 7 antagonist | |||
| 0.11 | 0.079 | 0.15 | Acetylcholine antagonist | 0.113 0.077 DBMET02383 0.102 0.09 DBMET02386 0.103 0.088 DBMET02384 0.15 0.05 DBMET02389 0.143 0.054 DBMET02390 | DBMET02389 | |
| 0.054 | 0.036 | 0.069 | Acetylcholine M2 receptor agonist | 0.054 0.037 DBMET02383 0.06 0.029 DBMET02386 0.052 0.04 DBMET02388 0.06 0.029 DBMET02384 0.061 0.027 DBMET02389 0.069 0.02 DBMET02390 | DBMET02390 | |
| 0.056 | 0.038 | 0.064 | Phosphodiesterase II inhibitor | 0.051 0.046 DBMET02383 0.054 0.04 DBMET02386 0.053 0.042 DBMET02388 0.051 0.047 DBMET02394 0.05 0.048 DBMET02384 0.064 0.027 DBMET02389 0.064 0.028 DBMET02390 | DBMET02390 | |
| 0.046 | 0.031 | 0.058 | Phosphodiesterase 6C inhibitor | 0.045 0.038 DBMET02383 0.046 0.034 DBMET02386 0.058 0.009 DBMET02388 0.047 0.029 DBMET02394 0.044 0.039 DBMET02384 0.047 0.028 DBMET02389 0.047 0.029 DBMET02390 0.044 0.04 DBMET02392 0.047 0.03 DBMET02393 | DBMET02388 | |
| 0.048 | 0.036 | 0.057 | Phosphodiesterase 2A inhibitor | 0.047 0.038 DBMET02386 0.046 0.04 DBMET02388 0.057 0.026 DBMET02389 0.056 0.027 DBMET02390 | DBMET02389 | |
| 0.146 | 0.14 | 0.146 | Potassium channel blocker | |||
| 0.028 | 0.026 | 0.031 | Phosphodiesterase 6B inhibitor | 0.031 0.02 DBMET02388 0.028 0.026 DBMET02394 0.029 0.024 DBMET02389 0.028 0.025 DBMET02390 0.029 0.024 DBMET02393 | DBMET02388 | |
| 0.054 | 0.054 | 0.063 | Phosphodiesterase VII inhibitor | 0.063 0.042 DBMET02393 | DBMET02393 | |
| 0.021 | 0.024 | 0.023 | Phosphodiesterase 6G inhibitor | 0.023 0.018 DBMET02388 0.022 0.021 DBMET02393 | DBMET02388 | |
| 0.021 | 0.024 | 0.023 | Phosphodiesterase 6H inhibitor | 0.023 0.018 DBMET02388 0.022 0.021 DBMET02393 | DBMET02388 | |
| 0.046 | 0.049 | 0.055 | Phosphodiesterase 7A inhibitor | 0.055 0.03 DBMET02393 | DBMET02393 | |
| 0.031 | 0.054 | 0.054 | Phosphodiesterase 3B inhibitor | 0.04 0.037 DBMET02388 0.051 0.024 DBMET02389 0.054 0.022 DBMET02390 | DBMET02390 | |
| 0.173 | 0.198 | 0.193 | Nootropic | 0.193 0.168 DBMET02389 | DBMET02389 | |
| 0.022 | 0.051 | 0.029 | DNA polymerase III inhibitor | 0.028 0.021 DBMET02386 0.026 0.025 DBMET02384 0.029 0.017 DBMET02390 0.027 0.021 DBMET02391 0.027 0.022 DBMET02392 0.029 0.017 DBMET02393 | DBMET02393 | |
| 0.05 | 0.084 | 0.113 | Phosphodiesterase 4D inhibitor | 0.113 0.031 DBMET02389 0.102 0.036 DBMET02390 | DBMET02389 | |
| 0.079 | 0.118 | 0.092 | mTOR complex 1 inhibitor | 0.092 0.082 DBMET02394 0.091 0.085 DBMET02391 | DBMET02394 | |
| 0.025 | 0.084 | 0.043 | Phosphodiesterase 4A inhibitor | 0.043 0.041 DBMET02388 | DBMET02388 | |
| 0.115 | 0.177 | 0.242 | Lipocortins synthesis antagonist | 0.14 0.121 DBMET02387 0.171 0.079 DBMET02388 0.135 0.13 DBMET02394 0.17 0.08 DBMET02389 0.141 0.119 DBMET02391 0.242 0.036 DBMET02392 0.183 0.068 DBMET02393 | DBMET02392 | |
| 0.005 | 0.073 | 0.024 | Prokineticin receptor 1 antagonist | 0.022 0.005 DBMET02391 0.023 0.005 DBMET02392 0.024 0.004 DBMET02393 | DBMET02393 | |
| 0.045 | 0.12 | 0.073 | Phosphodiesterase 1C inhibitor | 0.073 0.026 DBMET02393 | DBMET02393 | |
| 0.051 | 0.127 | 0.078 | Phosphodiesterase VI inhibitor | 0.078 0.044 DBMET02388 0.069 0.065 DBMET02391 0.071 0.058 DBMET02393 | DBMET02388 | |
| 0.169 | 0.248 | 0.627 | Antiobesity | 0.627 0.017 DBMET02385 0.231 0.176 DBMET02389 | DBMET02385 | |
| 0.034 | 0.127 | 0.074 | Phosphodiesterase 4B inhibitor | 0.064 0.051 DBMET02389 0.074 0.04 DBMET02390 | DBMET02390 | |
| 0.162 | 0.291 | 0.225 | Analgesic | 0.221 0.213 DBMET02389 0.225 0.208 DBMET02390 | DBMET02390 | |
| 0.038 | 0.172 | 0.082 | Phosphodiesterase 3A inhibitor | 0.082 0.052 DBMET02389 0.079 0.058 DBMET02390 | DBMET02389 | |
| 0.061 | 0.204 | 0.092 | Phosphodiesterase 6D inhibitor | 0.092 0.069 DBMET02391 0.091 0.074 DBMET02393 | DBMET02391 | |
| 0.073 | 0.22 | 0.163 | Diuretic | 0.163 0.067 DBMET02393 | DBMET02393 | |
| 0.049 | 0.216 | 0.083 | Phosphodiesterase 11A inhibitor | 0.083 0.053 DBMET02388 | DBMET02388 | |
| 0.049 | 0.216 | 0.083 | Phosphodiesterase XI inhibitor | 0.083 0.053 DBMET02388 | DBMET02388 | |
| 0.088 | 0.273 | 0.198 | Vasodilator | 0.198 0.106 DBMET02391 0.172 0.129 DBMET02393 | DBMET02391 | |
| 0.084 | 0.309 | 0.297 | Cardiotonic | 0.192 0.127 DBMET02388 0.182 0.138 DBMET02389 0.204 0.115 DBMET02390 0.297 0.057 DBMET02391 | DBMET02391 | |
| 0.15 | 0.376 | 0.312 | MAP kinase 1 inhibitor | 0.291 0.191 DBMET02383 0.312 0.168 DBMET02384 | DBMET02384 | |
| 0.067 | 0.302 | 0.192 | Spasmolytic | 0.178 0.139 DBMET02389 0.192 0.127 DBMET02390 | DBMET02390 | |
| 0.017 | 0.28 | 0.078 | Phosphodiesterase IV inhibitor | 0.078 0.063 DBMET02388 0.077 0.065 DBMET02390 | DBMET02388 | |
| 0.054 | 0.331 | 0.12 | Folate antagonist | 0.12 0.039 DBMET02393 | DBMET02393 | |
| 0.053 | 0.467 | 0.124 | Growth hormone agonist | 0.124 0.115 DBMET02393 | DBMET02393 | |
| 0.01 | 0.471 | 0.078 | HIV-1 reverse transcriptase inhibitor | 0.078 0.043 DBMET02392 | DBMET02392 | |
| 0.013 | 0.475 | 0.169 | HIV-1 integrase inhibitor | 0.169 0.006 DBMET02392 | DBMET02392 | |
| 0.043 | 0.624 | 0.194 | Vasodilator, coronary | 0.194 0.187 DBMET02391 | DBMET02391 | |
| 0.019 | 0.628 | 0.097 | CDC-like kinase 3 inhibitor | 0.095 0.092 DBMET02392 0.097 0.087 DBMET02393 | DBMET02393 | |
| 0.003 | 0.663 | 0.333 | Cholecystokinin agonist | 0.333 0.003 DBMET02385 | DBMET02385 | |
| 0.004 | 0.681 | 0.082 | Plasmin inhibitor | 0.082 0.021 DBMET02385 | DBMET02385 | |
| 0.011 | 0.723 | 0.078 | Dual specificity tyrosine-phosphorylation regulated kinase 2 inhibitor | 0.078 0.068 DBMET02387 | DBMET02387 | |
| 0.003 | 0.726 | 0.292 | Cholecystokinin A agonist | 0.292 0.002 DBMET02385 | DBMET02385 | |
| 0.009 | 0.751 | 0.066 | Trypsin inhibitor | 0.066 0.038 DBMET02385 | DBMET02385 | |
| 0.017 | 0.792 | 0.2 | Immunosuppressant | 0.2 0.197 DBMET02391 | DBMET02391 | |
| 0.031 | 0.823 | 0.212 | Sodium/bile acid cotransporter inhibitor | 0.212 0.172 DBMET02393 | DBMET02393 | |
| 0.003 | 0.798 | 0.035 | Trypsin I inhibitor | 0.035 0.021 DBMET02385 | DBMET02385 | |
| 0.005 | 0.825 | 0.088 | Plasminogen activator inhibitor | 0.088 0.021 DBMET02385 | DBMET02385 | |
| 0.003 | 0.927 | 0.091 | HIV-1 integrase (Strand Transfer) inhibitor | 0.091 0.026 DBMET02392 | DBMET02392 | Ext | Pa | Pi | Pmax | Activity | Other Results | ID Pa_max |