| Min Pa: | Min Pa(max): | Activity's type: |
| Ext | Pa | Pi | Pmax | Activity | Other Results | ID Pa_max |
|---|---|---|---|---|---|---|
| 0.902 | 0.005 | 0.902 | Cyclophilin D inhibitor | 0.898 0.005 DBMET00488 | ||
| 0.866 | 0.002 | 0.866 | Alcohol oxidase inhibitor | 0.19 0.007 DBMET00488 | ||
| 0.849 | 0.002 | 0.916 | Alpha-N-acetylglucosaminidase inhibitor | 0.916 0.001 DBMET00488 | DBMET00488 | |
| 0.828 | 0.012 | 0.916 | Antiinflammatory | 0.916 0.005 DBMET00488 | DBMET00488 | |
| 0.762 | 0.016 | 0.819 | Caspase 9 stimulant | 0.819 0.009 DBMET00488 | DBMET00488 | |
| 0.743 | 0.004 | 0.758 | Hypoglycemic | 0.758 0.004 DBMET00488 | DBMET00488 | |
| 0.73 | 0.004 | 0.879 | Angiogenesis stimulant | 0.879 0.003 DBMET00488 | DBMET00488 | |
| 0.73 | 0.006 | 0.73 | Aldehyde oxidase inhibitor | 0.192 0.109 DBMET00488 | ||
| 0.719 | 0.006 | 0.719 | 5 Hydroxytryptamine release stimulant | 0.529 0.023 DBMET00488 | ||
| 0.716 | 0.005 | 0.829 | Antioxidant | 0.829 0.004 DBMET00488 | DBMET00488 | |
| 0.708 | 0.029 | 0.793 | Apoptosis agonist | 0.793 0.017 DBMET00488 | DBMET00488 | |
| 0.628 | 0.004 | 0.628 | Interleukin 4 antagonist | 0.19 0.025 DBMET00488 | ||
| 0.629 | 0.007 | 0.768 | Free radical scavenger | 0.768 0.004 DBMET00488 | DBMET00488 | |
| 0.635 | 0.014 | 0.743 | Cholesterol antagonist | 0.743 0.005 DBMET00488 | DBMET00488 | |
| 0.62 | 0.008 | 0.62 | Apoptosis antagonist | 0.612 0.009 DBMET00488 | ||
| 0.61 | 0.012 | 0.665 | Immunosuppressant | 0.665 0.006 DBMET00488 | DBMET00488 | |
| 0.6 | 0.01 | 0.639 | Nitric oxide antagonist | 0.639 0.008 DBMET00488 | DBMET00488 | |
| 0.585 | 0.004 | 0.585 | Interleukin 2 agonist | 0.563 0.004 DBMET00488 | ||
| 0.584 | 0.004 | 0.708 | NOS3 expression enhancer | 0.708 0.003 DBMET00488 | DBMET00488 | |
| 0.585 | 0.009 | 0.585 | GABA C receptor rho-3 antagonist | |||
| 0.574 | 0.005 | 0.574 | Peroxidase inhibitor | 0.145 0.081 DBMET00488 | ||
| 0.579 | 0.014 | 0.767 | Immunomodulator | 0.767 0.005 DBMET00488 | DBMET00488 | |
| 0.567 | 0.005 | 0.768 | Hepatoprotectant | 0.768 0.003 DBMET00488 | DBMET00488 | |
| 0.559 | 0.003 | 0.559 | GABA C receptor agonist | 0.251 0.013 DBMET00488 | ||
| 0.573 | 0.019 | 0.573 | Vasodilator, peripheral | 0.433 0.046 DBMET00488 | ||
| 0.54 | 0.002 | 0.637 | Triose-phosphate isomerase inhibitor | 0.637 0.002 DBMET00488 | DBMET00488 | |
| 0.528 | 0.003 | 0.691 | NADH dehydrogenase inhibitor | 0.691 0.001 DBMET00488 | DBMET00488 | |
| 0.544 | 0.021 | 0.593 | 5 Hydroxytryptamine release inhibitor | 0.593 0.012 DBMET00488 | DBMET00488 | |
| 0.535 | 0.016 | 0.535 | Caspase 3 stimulant | 0.399 0.045 DBMET00488 | ||
| 0.519 | 0.005 | 0.519 | Insulin secretagoues | 0.43 0.005 DBMET00488 | ||
| 0.528 | 0.021 | 0.657 | Histamine release inhibitor | 0.657 0.006 DBMET00488 | DBMET00488 | |
| 0.511 | 0.007 | 0.562 | Anesthetic general | 0.562 0.005 DBMET00488 | DBMET00488 | |
| 0.494 | 0.003 | 0.594 | UDP-glucose 4-epimerase inhibitor | 0.594 0.001 DBMET00488 | DBMET00488 | |
| 0.494 | 0.013 | 0.494 | Superoxide dismutase inhibitor | |||
| 0.51 | 0.029 | 0.51 | Ca2+/calmodulin-dependent protein kinase kinase A inhibitor | |||
| 0.482 | 0.005 | 0.482 | 5 Hydroxytryptamine uptake stimulant | 0.216 0.123 DBMET00488 | ||
| 0.49 | 0.013 | 0.49 | Vasodilator | 0.481 0.013 DBMET00488 | ||
| 0.48 | 0.007 | 0.48 | Calcium channel activator | 0.249 0.149 DBMET00488 | ||
| 0.48 | 0.007 | 0.48 | Phospholipase C inhibitor | 0.365 0.013 DBMET00488 | ||
| 0.471 | 0.004 | 0.513 | Peptidyltransferase inhibitor | 0.513 0.003 DBMET00488 | DBMET00488 | |
| 0.468 | 0.007 | 0.713 | Amylase inhibitor | 0.713 0.003 DBMET00488 | DBMET00488 | |
| 0.467 | 0.007 | 0.502 | Platelet adhesion inhibitor | 0.502 0.005 DBMET00488 | DBMET00488 | |
| 0.466 | 0.016 | 0.599 | DNA synthesis inhibitor | 0.599 0.007 DBMET00488 | DBMET00488 | |
| 0.489 | 0.04 | 0.489 | Antiobesity | 0.315 0.106 DBMET00488 | ||
| 0.455 | 0.017 | 0.468 | Hypolipemic | 0.468 0.015 DBMET00488 | DBMET00488 | |
| 0.451 | 0.013 | 0.555 | Interleukin agonist | 0.555 0.006 DBMET00488 | DBMET00488 | |
| 0.442 | 0.009 | 0.442 | Sodium/bile acid cotransporter inhibitor | 0.23 0.15 DBMET00488 | ||
| 0.446 | 0.014 | 0.477 | RNA-directed DNA polymerase inhibitor | 0.477 0.012 DBMET00488 | DBMET00488 | |
| 0.454 | 0.023 | 0.509 | Vasodilator, coronary | 0.509 0.014 DBMET00488 | DBMET00488 | |
| 0.449 | 0.019 | 0.521 | Platelet antagonist | 0.521 0.012 DBMET00488 | DBMET00488 | |
| 0.476 | 0.048 | 0.668 | Antibacterial | 0.668 0.011 DBMET00488 | DBMET00488 | |
| 0.43 | 0.005 | 0.43 | DNA polymerase I inhibitor | 0.248 0.017 DBMET00488 | ||
| 0.423 | 0.003 | 0.546 | Selectin antagonist | 0.546 0.002 DBMET00488 | DBMET00488 | |
| 0.436 | 0.021 | 0.58 | Tumour necrosis factor alpha release inhibitor | 0.58 0.008 DBMET00488 | DBMET00488 | |
| 0.417 | 0.003 | 0.417 | Carbamoyl phosphate synthetase inhibitor | 0.191 0.008 DBMET00488 | ||
| 0.45 | 0.038 | 0.773 | Antithrombotic | 0.773 0.005 DBMET00488 | DBMET00488 | |
| 0.41 | 0.005 | 0.41 | Topoisomerase I inhibitor | 0.406 0.005 DBMET00488 | ||
| 0.412 | 0.009 | 0.523 | Lipid peroxidase inhibitor | 0.523 0.005 DBMET00488 | DBMET00488 | |
| 0.404 | 0.004 | 0.464 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor | 0.464 0.003 DBMET00488 | DBMET00488 | |
| 0.4 | 0.003 | 0.514 | Phosphofructokinase-1 inhibitor | 0.514 0.002 DBMET00488 | DBMET00488 | |
| 0.399 | 0.004 | 0.399 | Nitric-oxide synthase stimulant | 0.312 0.009 DBMET00488 | ||
| 0.449 | 0.053 | 0.728 | Transcription factor NF kappa B inhibitor | 0.728 0.018 DBMET00488 | DBMET00488 | |
| 0.402 | 0.008 | 0.402 | Tyrosine 3 hydroxylase inhibitor | 0.186 0.163 DBMET00488 | ||
| 0.388 | 0.004 | 0.388 | Adenylate kinase inhibitor | 0.31 0.006 DBMET00488 | ||
| 0.387 | 0.004 | 0.387 | Ferrochelatase inhibitor | 0.144 0.04 DBMET00488 | ||
| 0.388 | 0.009 | 0.388 | Glyceraldehyde-3-phosphate dehydrogenase inhibitor | 0.303 0.023 DBMET00488 | ||
| 0.392 | 0.026 | 0.392 | Amyloid beta aggregation inhibitor | |||
| 0.369 | 0.006 | 0.369 | Cystathionine beta-synthase inhibitor | 0.257 0.014 DBMET00488 | ||
| 0.373 | 0.011 | 0.373 | Lipocortins synthesis antagonist | 0.174 0.077 DBMET00488 | ||
| 0.36 | 0.004 | 0.36 | Glutamate dehydrogenase inhibitor | 0.219 0.009 DBMET00488 | ||
| 0.372 | 0.021 | 0.408 | Cyclic AMP phosphodiesterase inhibitor | 0.408 0.015 DBMET00488 | DBMET00488 | |
| 0.356 | 0.005 | 0.356 | Histidine decarboxylase inhibitor | 0.084 0.04 DBMET00488 | ||
| 0.35 | 0.003 | 0.35 | Creatine kinase inhibitor | 0.129 0.035 DBMET00488 | ||
| 0.349 | 0.01 | 0.401 | Interleukin 6 antagonist | 0.401 0.007 DBMET00488 | DBMET00488 | |
| 0.351 | 0.014 | 0.397 | Interferon gamma antagonist | 0.397 0.011 DBMET00488 | DBMET00488 | |
| 0.39 | 0.053 | 0.606 | Immunostimulant | 0.606 0.016 DBMET00488 | DBMET00488 | |
| 0.351 | 0.016 | 0.359 | Melanin inhibitor | 0.359 0.015 DBMET00488 | DBMET00488 | |
| 0.339 | 0.006 | 0.339 | Succinate dehydrogenase inhibitor | 0.22 0.035 DBMET00488 | ||
| 0.339 | 0.01 | 0.339 | Neurotrophic factor enhancer | 0.315 0.014 DBMET00488 | ||
| 0.335 | 0.013 | 0.46 | Protein kinase stimulant | 0.46 0.005 DBMET00488 | DBMET00488 | |
| 0.329 | 0.008 | 0.389 | Antineoplastic antibiotic | 0.389 0.005 DBMET00488 | DBMET00488 | |
| 0.339 | 0.018 | 0.505 | Thrombolytic | 0.505 0.005 DBMET00488 | DBMET00488 | |
| 0.322 | 0.004 | 0.413 | Mannose-6-phosphate isomerase inhibitor | 0.413 0.003 DBMET00488 | DBMET00488 | |
| 0.319 | 0.005 | 0.319 | Porphobilinogen synthase inhibitor | 0.08 0.047 DBMET00488 | ||
| 0.315 | 0.003 | 0.315 | Biliverdin reductase inhibitor | 0.218 0.005 DBMET00488 | ||
| 0.328 | 0.018 | 0.328 | Gastrin inhibitor | 0.258 0.07 DBMET00488 | ||
| 0.317 | 0.009 | 0.471 | Hexokinase inhibitor | 0.471 0.003 DBMET00488 | DBMET00488 | |
| 0.347 | 0.042 | 0.418 | DNA damaging | 0.418 0.025 DBMET00488 | DBMET00488 | |
| 0.326 | 0.027 | 0.326 | Growth hormone agonist | |||
| 0.307 | 0.011 | 0.391 | Aldehyde dehydrogenase inhibitor | 0.391 0.006 DBMET00488 | DBMET00488 | |
| 0.301 | 0.006 | 0.322 | ATPase inhibitor | 0.322 0.005 DBMET00488 | DBMET00488 | |
| 0.296 | 0.004 | 0.296 | Mannitol-1-phosphate 5-dehydrogenase inhibitor | 0.276 0.004 DBMET00488 | ||
| 0.287 | 0.005 | 0.287 | GABA C receptor antagonist | 0.1 0.078 DBMET00488 | ||
| 0.398 | 0.116 | 0.665 | Alpha-glucosidase inhibitor | 0.665 0.04 DBMET00488 | DBMET00488 | |
| 0.284 | 0.002 | 0.403 | Alpha-mannosidase inhibitor | 0.403 0.001 DBMET00488 | DBMET00488 | |
| 0.282 | 0.003 | 0.282 | Adenylate cyclase stimulant | 0.195 0.016 DBMET00488 | ||
| 0.282 | 0.004 | 0.282 | Argininosuccinate synthase inhibitor | 0.192 0.008 DBMET00488 | ||
| 0.279 | 0.004 | 0.279 | CF transmembrane conductance regulator agonist | 0.195 0.025 DBMET00488 | ||
| 0.273 | 0.004 | 0.273 | Phenylalanine 4-hydroxylase inhibitor | 0.077 0.04 DBMET00488 | ||
| 0.328 | 0.06 | 0.513 | Spasmolytic | 0.513 0.021 DBMET00488 | DBMET00488 | |
| 0.268 | 0.003 | 0.268 | Fumarate hydratase inhibitor | 0.116 0.005 DBMET00488 | ||
| 0.294 | 0.03 | 0.389 | DNA methylase inhibitor | 0.389 0.012 DBMET00488 | DBMET00488 | |
| 0.321 | 0.056 | 0.44 | Hypoxia-inducible factor 1 alpha inhibitor | 0.44 0.022 DBMET00488 | DBMET00488 | |
| 0.305 | 0.041 | 0.305 | Psychostimulant | 0.247 0.06 DBMET00488 | ||
| 0.277 | 0.016 | 0.277 | Adenylate cyclase inhibitor | 0.268 0.017 DBMET00488 | ||
| 0.288 | 0.031 | 0.366 | DNA methyltransferase I inhibitor | 0.366 0.012 DBMET00488 | DBMET00488 | |
| 0.277 | 0.021 | 0.449 | Topoisomerase II inhibitor | 0.449 0.008 DBMET00488 | DBMET00488 | |
| 0.259 | 0.002 | 0.422 | Mannosidase inhibitor | 0.422 0.001 DBMET00488 | DBMET00488 | |
| 0.269 | 0.013 | 0.414 | Cell wall synthesis inhibitor | 0.414 0.005 DBMET00488 | DBMET00488 | |
| 0.261 | 0.006 | 0.261 | Estrogen agonist | 0.058 0.031 DBMET00488 | ||
| 0.264 | 0.013 | 0.517 | Cell adhesion inhibitor | 0.517 0.004 DBMET00488 | DBMET00488 | |
| 0.283 | 0.032 | 0.283 | P-glycoprotein inhibitor | 0.154 0.111 DBMET00488 | ||
| 0.253 | 0.005 | 0.253 | Arachidonic acid antagonist | 0.205 0.029 DBMET00488 | ||
| 0.259 | 0.012 | 0.53 | Expectorant | 0.53 0.003 DBMET00488 | DBMET00488 | |
| 0.301 | 0.055 | 0.301 | Cardiotonic | |||
| 0.249 | 0.003 | 0.249 | Acyl-CoA dehydrogenase inhibitor | 0.17 0.007 DBMET00488 | ||
| 0.253 | 0.009 | 0.253 | Carbonic anhydrase III inhibitor | 0.158 0.026 DBMET00488 | ||
| 0.3 | 0.058 | 0.3 | Insulysin inhibitor | |||
| 0.245 | 0.006 | 0.245 | Photosensitizer | 0.233 0.008 DBMET00488 | ||
| 0.256 | 0.017 | 0.256 | Cholesterol synthesis inhibitor | 0.178 0.033 DBMET00488 | ||
| 0.296 | 0.058 | 0.296 | Transcription factor STAT inhibitor | |||
| 0.272 | 0.035 | 0.478 | Non-steroidal antiinflammatory agent | 0.478 0.008 DBMET00488 | DBMET00488 | |
| 0.245 | 0.01 | 0.245 | Microtubule formation inhibitor | 0.244 0.01 DBMET00488 | ||
| 0.24 | 0.009 | 0.24 | Estrogen antagonist | |||
| 0.243 | 0.013 | 0.243 | GABA C receptor rho-2 antagonist | |||
| 0.259 | 0.029 | 0.259 | Insulin sensitizer | 0.19 0.084 DBMET00488 | ||
| 0.287 | 0.06 | 0.287 | Transcription factor STAT3 inhibitor | 0.176 0.17 DBMET00488 | ||
| 0.253 | 0.028 | 0.253 | Cytidine deaminase inhibitor | |||
| 0.223 | 0.001 | 0.332 | Glucose-6-phosphate isomerase inhibitor | 0.332 0.001 DBMET00488 | DBMET00488 | |
| 0.222 | 0.002 | 0.225 | Ca2+-transporting ATPase inhibitor | 0.225 0.002 DBMET00488 | DBMET00488 | |
| 0.222 | 0.004 | 0.222 | Glycine receptor agonist | 0.195 0.004 DBMET00488 | ||
| 0.228 | 0.012 | 0.57 | Cyclooxygenase 3 inhibitor | 0.57 0.003 DBMET00488 | DBMET00488 | |
| 0.218 | 0.006 | 0.218 | GABA C receptor rho-1 antagonist | 0.093 0.073 DBMET00488 | ||
| 0.222 | 0.009 | 0.258 | Mucolytic | 0.258 0.006 DBMET00488 | DBMET00488 | |
| 0.229 | 0.017 | 0.229 | Neurotrophic factor | 0.163 0.049 DBMET00488 | ||
| 0.226 | 0.015 | 0.226 | Bronchodilator | |||
| 0.215 | 0.004 | 0.215 | Glutamate release inhibitor | 0.185 0.005 DBMET00488 | ||
| 0.219 | 0.009 | 0.404 | AMP-activated protein kinase stimulant | 0.404 0.004 DBMET00488 | DBMET00488 | |
| 0.214 | 0.006 | 0.214 | Glutamate decarboxylase inhibitor | 0.097 0.032 DBMET00488 | ||
| 0.227 | 0.02 | 0.439 | Alkylator | 0.439 0.006 DBMET00488 | DBMET00488 | |
| 0.216 | 0.01 | 0.216 | Antineoplastic alkaloid | |||
| 0.232 | 0.026 | 0.232 | 5 Hydroxytryptamine 3E antagonist | |||
| 0.205 | 0.003 | 0.205 | Glycine receptor antagonist | 0.204 0.003 DBMET00488 | ||
| 0.207 | 0.006 | 0.207 | Prostaglandin EP2 antagonist | 0.066 0.036 DBMET00488 | ||
| 0.209 | 0.01 | 0.209 | HIV-1 integrase (Overall Integration) inhibitor | |||
| 0.207 | 0.009 | 0.319 | Transcription factor NF kappa B stimulant | 0.319 0.004 DBMET00488 | DBMET00488 | |
| 0.203 | 0.006 | 0.203 | Heat shock protein 70 antagonist | 0.179 0.012 DBMET00488 | ||
| 0.21 | 0.012 | 0.21 | Carbonic anhydrase VI inhibitor | 0.112 0.033 DBMET00488 | ||
| 0.201 | 0.004 | 0.201 | Lanosterol 14 alpha demethylase inhibitor | |||
| 0.222 | 0.028 | 0.302 | Monophenol monooxygenase inhibitor | 0.302 0.018 DBMET00488 | DBMET00488 | |
| 0.195 | 0.007 | 0.195 | Ornithine carbamoyltransferase inhibitor | 0.109 0.014 DBMET00488 | ||
| 0.196 | 0.009 | 0.196 | Electrolyte absorption antagonist | |||
| 0.193 | 0.006 | 0.193 | Interferon agonist | 0.141 0.012 DBMET00488 | ||
| 0.196 | 0.01 | 0.196 | Sphingomyelinase inhibitor | 0.196 0.01 DBMET00488 | ||
| 0.213 | 0.028 | 0.528 | Hemostatic | 0.528 0.004 DBMET00488 | DBMET00488 | |
| 0.189 | 0.005 | 0.259 | Neuraminidase (influenza) inhibitor | 0.259 0.004 DBMET00488 | DBMET00488 | |
| 0.202 | 0.018 | 0.202 | Carbonic anhydrase XV inhibitor | |||
| 0.191 | 0.008 | 0.219 | Toll-Like receptor 4 antagonist | 0.219 0.005 DBMET00488 | DBMET00488 | |
| 0.192 | 0.009 | 0.192 | Keratolytic | 0.071 0.063 DBMET00488 | ||
| 0.204 | 0.022 | 0.204 | Toll-Like receptor 2 antagonist | 0.161 0.045 DBMET00488 | ||
| 0.225 | 0.044 | 0.225 | Growth factor agonist | |||
| 0.194 | 0.015 | 0.194 | Carbonic anhydrase XIII inhibitor | 0.156 0.02 DBMET00488 | ||
| 0.202 | 0.024 | 0.202 | Chelator | 0.111 0.063 DBMET00488 | ||
| 0.187 | 0.009 | 0.187 | DOPA decarboxylase inhibitor | 0.104 0.069 DBMET00488 | ||
| 0.199 | 0.021 | 0.199 | Aminopeptidase B inhibitor | 0.089 0.073 DBMET00488 | ||
| 0.182 | 0.004 | 0.182 | Purinergic P2X1 antagonist | 0.125 0.01 DBMET00488 | ||
| 0.191 | 0.014 | 0.43 | Beta glucuronidase inhibitor | 0.43 0.004 DBMET00488 | DBMET00488 | |
| 0.187 | 0.01 | 0.187 | HIV-1 integrase (Strand Transfer) inhibitor | 0.082 0.03 DBMET00488 | ||
| 0.179 | 0.003 | 0.179 | Glucosylceramidase inhibitor | 0.074 0.019 DBMET00488 | ||
| 0.317 | 0.143 | 0.317 | Calcium channel L-type activator | |||
| 0.179 | 0.007 | 0.179 | Anabolic | 0.128 0.032 DBMET00488 | ||
| 0.184 | 0.012 | 0.184 | Prolactin inhibitor | |||
| 0.206 | 0.035 | 0.206 | Heat shock protein 90 antagonist | |||
| 0.237 | 0.067 | 0.237 | Interleukin antagonist | |||
| 0.175 | 0.005 | 0.175 | Estrogen receptor beta agonist | |||
| 0.186 | 0.017 | 0.266 | Topoisomerase II alpha inhibitor | 0.266 0.009 DBMET00488 | DBMET00488 | |
| 0.181 | 0.013 | 0.272 | DNA repair enzyme inhibitor | 0.272 0.005 DBMET00488 | DBMET00488 | |
| 0.182 | 0.014 | 0.182 | Alcohol dehydrogenase inhibitor | 0.137 0.025 DBMET00488 | ||
| 0.213 | 0.045 | 0.213 | 3C-like protease (Human coronavirus) inhibitor | |||
| 0.186 | 0.018 | 0.186 | Catalase inhibitor | 0.098 0.039 DBMET00488 | ||
| 0.178 | 0.013 | 0.178 | Aminoacyl-tRNA synthetase inhibitor | |||
| 0.168 | 0.004 | 0.168 | Aconitate hydratase inhibitor | 0.075 0.016 DBMET00488 | ||
| 0.172 | 0.009 | 0.172 | Aminopeptidase I inhibitor | 0.079 0.043 DBMET00488 | ||
| 0.179 | 0.016 | 0.285 | Uric acid excretion stimulant | 0.285 0.005 DBMET00488 | DBMET00488 | |
| 0.179 | 0.019 | 0.179 | Pregnane X receptor agonist | |||
| 0.179 | 0.019 | 0.179 | Vanilloid 1 agonist | 0.144 0.045 DBMET00488 | ||
| 0.201 | 0.044 | 0.458 | Diuretic | 0.458 0.01 DBMET00488 | DBMET00488 | |
| 0.195 | 0.037 | 0.195 | Neurotensin receptor agonist | |||
| 0.163 | 0.006 | 0.164 | GABA aminotransferase inhibitor | 0.164 0.006 DBMET00488 | DBMET00488 | |
| 0.241 | 0.085 | 0.241 | 5 Hydroxytryptamine 1E antagonist | |||
| 0.162 | 0.006 | 0.176 | Protein 50S ribosomal subunit inhibitor | 0.176 0.005 DBMET00488 | DBMET00488 | |
| 0.159 | 0.005 | 0.221 | Neuraminidase inhibitor | 0.221 0.004 DBMET00488 | DBMET00488 | |
| 0.182 | 0.028 | 0.182 | Farnesoid X receptor antagonist | |||
| 0.166 | 0.013 | 0.245 | Thioredoxin inhibitor | 0.245 0.005 DBMET00488 | DBMET00488 | |
| 0.165 | 0.013 | 0.165 | Estrogen receptor beta antagonist | |||
| 0.176 | 0.026 | 0.226 | Beta amyloid protein antagonist | 0.226 0.011 DBMET00488 | DBMET00488 | |
| 0.175 | 0.026 | 0.302 | Xanthine oxidase inhibitor | 0.302 0.007 DBMET00488 | DBMET00488 | |
| 0.153 | 0.004 | 0.153 | Glutamate (mGluR6) antagonist | 0.089 0.016 DBMET00488 | ||
| 0.179 | 0.03 | 0.179 | Cathepsin H inhibitor | |||
| 0.219 | 0.07 | 0.219 | MAP kinase kinase 2 inhibitor | |||
| 0.229 | 0.082 | 0.381 | Antiamyloidogenic | 0.381 0.032 DBMET00488 | DBMET00488 | |
| 0.185 | 0.039 | 0.185 | NADPH oxidase inhibitor | 0.131 0.07 DBMET00488 | ||
| 0.151 | 0.007 | 0.151 | ATPase (Vacuolar H+) inhibitor | 0.13 0.014 DBMET00488 | ||
| 0.216 | 0.073 | 0.216 | Pyruvate kinase inhibitor | 0.135 0.13 DBMET00488 | ||
| 0.165 | 0.025 | 0.165 | Sphingosine 1-phosphate receptor 2 antagonist | |||
| 0.163 | 0.024 | 0.163 | Potassium channel (Ca-activated) activator | |||
| 0.193 | 0.054 | 0.193 | Antipruritic | |||
| 0.143 | 0.005 | 0.143 | Interferon inducer | 0.112 0.009 DBMET00488 | ||
| 0.147 | 0.01 | 0.147 | Phosphodiesterase 6D inhibitor | 0.139 0.013 DBMET00488 | ||
| 0.17 | 0.033 | 0.17 | Sphingosine 1-phosphate receptor 5 antagonist | |||
| 0.141 | 0.005 | 0.141 | Estrogen-related receptor beta agonist | |||
| 0.163 | 0.027 | 0.163 | Interleukin 8 antagonist | |||
| 0.141 | 0.005 | 0.141 | Estrogen receptor alpha agonist | |||
| 0.165 | 0.03 | 0.165 | Falcipain 3 inhibitor | |||
| 0.15 | 0.016 | 0.15 | Acetylcholine release stimulant | 0.143 0.022 DBMET00488 | ||
| 0.162 | 0.029 | 0.162 | 5 Hydroxytryptamine 3A agonist | |||
| 0.147 | 0.014 | 0.147 | HIV-1 integrase (3'-Processing) inhibitor | 0.084 0.032 DBMET00488 | ||
| 0.158 | 0.027 | 0.158 | Protein kinase C gamma inhibitor | 0.099 0.079 DBMET00488 | ||
| 0.136 | 0.005 | 0.136 | Prostaglandin F2 alpha antagonist | |||
| 0.144 | 0.014 | 0.144 | Glutamate (mGluR7) agonist | |||
| 0.156 | 0.027 | 0.156 | TRPA1 agonist | 0.1 0.088 DBMET00488 | ||
| 0.132 | 0.004 | 0.139 | Glucose-6-phosphate translocase inhibitor | 0.139 0.004 DBMET00488 | DBMET00488 | |
| 0.147 | 0.02 | 0.147 | NAD(P)H dehydrogenase (quinone) inhibitor | |||
| 0.15 | 0.023 | 0.15 | Transcription factor STAT6 inhibitor | |||
| 0.134 | 0.01 | 0.149 | Na+ K+ transporting ATPase inhibitor | 0.149 0.006 DBMET00488 | DBMET00488 | |
| 0.141 | 0.018 | 0.141 | Histamine N-methyltransferase inhibitor | |||
| 0.128 | 0.005 | 0.128 | RNA-directed RNA polymerase stimulant | |||
| 0.128 | 0.005 | 0.128 | S-adenosyl-L-methionine decarboxylase inhibitor | 0.07 0.06 DBMET00488 | ||
| 0.127 | 0.004 | 0.127 | Purinergic P2T antagonist | |||
| 0.176 | 0.054 | 0.176 | Acetylcholine M1 receptor antagonist | |||
| 0.126 | 0.005 | 0.126 | Phospholipase D inhibitor | 0.068 0.058 DBMET00488 | ||
| 0.131 | 0.01 | 0.131 | Granulocyte macrophage colony stimulating factor agonist | |||
| 0.13 | 0.009 | 0.13 | Androgen agonist | |||
| 0.125 | 0.004 | 0.125 | Sphingosine kinase 2 inhibitor | |||
| 0.159 | 0.039 | 0.159 | Antibacterial (Helicobacter pylori) | 0.153 0.044 DBMET00488 | ||
| 0.181 | 0.062 | 0.181 | Heat shock protein 90 alpha antagonist | |||
| 0.127 | 0.009 | 0.236 | Phosphorylase inhibitor | 0.236 0.004 DBMET00488 | DBMET00488 | |
| 0.146 | 0.028 | 0.181 | CC chemokine 6 receptor antagonist | 0.181 0.005 DBMET00488 | DBMET00488 | |
| 0.161 | 0.044 | 0.161 | MAP kinase kinase 4 inhibitor | |||
| 0.123 | 0.005 | 0.123 | Phosphoglycerate kinase inhibitor | 0.046 0.016 DBMET00488 | ||
| 0.123 | 0.006 | 0.123 | Vanilloid 4 agonist | |||
| 0.12 | 0.003 | 0.12 | Adenylate cyclase 1 inhibitor | |||
| 0.258 | 0.141 | 0.258 | Toll-Like receptor agonist | |||
| 0.134 | 0.019 | 0.134 | Interleukin 12 antagonist | 0.103 0.049 DBMET00488 | ||
| 0.122 | 0.007 | 0.122 | GABA B receptor agonist | |||
| 0.13 | 0.014 | 0.299 | Histone deacetylase stimulant | 0.299 0.004 DBMET00488 | DBMET00488 | |
| 0.13 | 0.014 | 0.299 | Histone deacetylase SIRT1 stimulant | 0.299 0.004 DBMET00488 | DBMET00488 | |
| 0.116 | 0.002 | 0.119 | Antibiotic Aminoglycoside-like | 0.119 0.002 DBMET00488 | DBMET00488 | |
| 0.118 | 0.005 | 0.118 | MAP kinase kinase 7 inhibitor | |||
| 0.128 | 0.014 | 0.128 | mTOR complex 2 inhibitor | |||
| 0.12 | 0.007 | 0.12 | 3(or 17)beta-hydroxysteroid dehydrogenase inhibitor | |||
| 0.131 | 0.019 | 0.131 | Ornithine decarboxylase inhibitor | 0.122 0.024 DBMET00488 | ||
| 0.124 | 0.012 | 0.124 | D-Ala-D-Ala ligase inhibitor | |||
| 0.126 | 0.015 | 0.126 | Bile acid receptor antagonist | 0.103 0.044 DBMET00488 | ||
| 0.137 | 0.026 | 0.137 | Androgen antagonist | |||
| 0.197 | 0.086 | 0.197 | Antimitotic | |||
| 0.115 | 0.005 | 0.115 | Sphingosine kinase inhibitor | |||
| 0.115 | 0.005 | 0.115 | Glutamate (mGluR7) antagonist | |||
| 0.135 | 0.026 | 0.135 | Potassium channel activator | |||
| 0.142 | 0.033 | 0.164 | Mediator release inhibitor | 0.164 0.023 DBMET00488 | DBMET00488 | |
| 0.146 | 0.037 | 0.146 | Sphingosine 1-phosphate receptor 4 antagonist | |||
| 0.132 | 0.025 | 0.132 | MAP kinase kinase 1 inhibitor | |||
| 0.112 | 0.005 | 0.112 | Exportin-1 inhibitor | |||
| 0.128 | 0.023 | 0.128 | Macrophage migration inhibitory factor inhibitor | |||
| 0.209 | 0.104 | 0.209 | Neuropeptide Y2 antagonist | |||
| 0.107 | 0.003 | 0.107 | Protein 30S ribosomal subunit inhibitor | 0.09 0.004 DBMET00488 | ||
| 0.159 | 0.055 | 0.159 | MAP kinase 3 inhibitor | |||
| 0.124 | 0.02 | 0.124 | Carbonic anhydrase V inhibitor | |||
| 0.175 | 0.072 | 0.175 | Tumour necrosis factor antagonist | |||
| 0.25 | 0.148 | 0.25 | Toll-Like receptor 7 agonist | |||
| 0.106 | 0.004 | 0.106 | Lipocortins synthesis agonist | 0.098 0.006 DBMET00488 | ||
| 0.146 | 0.047 | 0.184 | Protein-tyrosine phosphatase 1B inhibitor | 0.184 0.034 DBMET00488 | DBMET00488 | |
| 0.121 | 0.024 | 0.24 | Cell adhesion molecule inhibitor | 0.24 0.007 DBMET00488 | DBMET00488 | |
| 0.141 | 0.044 | 0.141 | Papain-like protease (SARS coronavirus) inhibitor | |||
| 0.101 | 0.004 | 0.101 | Ryanodine receptor antagonist | |||
| 0.105 | 0.009 | 0.105 | Topoisomerase II beta inhibitor | 0.061 0.021 DBMET00488 | ||
| 0.115 | 0.019 | 0.115 | Carbonic anhydrase VA inhibitor | |||
| 0.099 | 0.004 | 0.099 | Dopamine D5 agonist | |||
| 0.162 | 0.068 | 0.162 | Cyclin-dependent kinase 8 inhibitor | |||
| 0.113 | 0.018 | 0.113 | HIV-1 integrase inhibitor | |||
| 0.13 | 0.036 | 0.13 | Gastric antisecretory | |||
| 0.145 | 0.051 | 0.145 | Anesthetic local | |||
| 0.149 | 0.056 | 0.149 | Nav1.6 sodium channel blocker | |||
| 0.098 | 0.005 | 0.098 | Squalene epoxidase inhibitor | 0.066 0.016 DBMET00488 | ||
| 0.113 | 0.02 | 0.113 | Adenosine A3 receptor antagonist | 0.073 0.054 DBMET00488 | ||
| 0.185 | 0.092 | 0.185 | Histone acetyltransferase inhibitor | |||
| 0.095 | 0.003 | 0.127 | Sodium/glucose cotransporter 2 inhibitor | 0.127 0.002 DBMET00488 | DBMET00488 | |
| 0.113 | 0.022 | 0.113 | Vanilloid agonist | |||
| 0.106 | 0.015 | 0.106 | Antimetabolite | 0.106 0.015 DBMET00488 | ||
| 0.106 | 0.015 | 0.106 | 3-Oxoacyl-[acyl-carrier-protein] synthase inhibitor | 0.092 0.019 DBMET00488 | ||
| 0.122 | 0.031 | 0.122 | Protein kinase C zeta inhibitor | |||
| 0.107 | 0.017 | 0.141 | Aldose reductase inhibitor | 0.141 0.011 DBMET00488 | DBMET00488 | |
| 0.092 | 0.003 | 0.092 | Kainate receptor agonist | 0.051 0.013 DBMET00488 | ||
| 0.1 | 0.011 | 0.1 | Heat shock protein 90 beta antagonist | |||
| 0.101 | 0.013 | 0.101 | Protein kinase C beta inhibitor | 0.076 0.037 DBMET00488 | ||
| 0.093 | 0.005 | 0.093 | Glutamate (mGluR3) antagonist | |||
| 0.093 | 0.005 | 0.093 | Potassium channel (Inward rectifier) activator | |||
| 0.112 | 0.024 | 0.112 | Myeloperoxidase inhibitor | |||
| 0.09 | 0.004 | 0.09 | Pregnane X receptor antagonist | |||
| 0.25 | 0.164 | 0.25 | 15-Lipoxygenase inhibitor | |||
| 0.177 | 0.092 | 0.177 | I kappa B kinase epsilon inhibitor | |||
| 0.09 | 0.005 | 0.09 | Potassium channel (ATP-sensitive) activator | |||
| 0.192 | 0.107 | 0.192 | Aryl hydrocarbon receptor agonist | |||
| 0.103 | 0.019 | 0.103 | CC chemokine 5 receptor agonist | |||
| 0.089 | 0.007 | 0.098 | Adenosine deaminase inhibitor | 0.098 0.006 DBMET00488 | DBMET00488 | |
| 0.111 | 0.029 | 0.111 | Glutathione S-transferase inhibitor | |||
| 0.085 | 0.004 | 0.085 | Glutamate (mGluR8) agonist | 0.044 0.017 DBMET00488 | ||
| 0.09 | 0.009 | 0.09 | Calcium channel P-type blocker | |||
| 0.101 | 0.02 | 0.101 | Acetylcholine M5 receptor agonist | |||
| 0.093 | 0.013 | 0.118 | Carbonic anhydrase XIV inhibitor | 0.118 0.007 DBMET00488 | DBMET00488 | |
| 0.144 | 0.064 | 0.282 | Bone formation stimulant | 0.282 0.019 DBMET00488 | DBMET00488 | |
| 0.094 | 0.015 | 0.094 | Toll-Like receptor 2 agonist | 0.073 0.017 DBMET00488 | ||
| 0.097 | 0.018 | 0.097 | Protein kinase C eta inhibitor | 0.073 0.027 DBMET00488 | ||
| 0.084 | 0.005 | 0.084 | Sphingosine kinase 1 inhibitor | |||
| 0.083 | 0.005 | 0.14 | Cytokine production stimulant | 0.14 0.003 DBMET00488 | DBMET00488 | |
| 0.153 | 0.075 | 0.191 | Protein-tyrosine phosphatase inhibitor | 0.191 0.05 DBMET00488 | DBMET00488 | |
| 0.081 | 0.003 | 0.125 | Sodium/glucose cotransporter inhibitor | 0.125 0.002 DBMET00488 | DBMET00488 | |
| 0.142 | 0.065 | 0.155 | Alkaline phosphatase inhibitor | 0.155 0.057 DBMET00488 | DBMET00488 | |
| 0.109 | 0.032 | 0.109 | CYP2A6 inhibitor | |||
| 0.103 | 0.025 | 0.103 | Estrogen receptor alpha antagonist | |||
| 0.109 | 0.032 | 0.109 | Interleukin 5 antagonist | |||
| 0.079 | 0.003 | 0.081 | Guanylate cyclase inhibitor | 0.081 0.003 DBMET00488 | DBMET00488 | |
| 0.121 | 0.044 | 0.121 | Urease inhibitor | |||
| 0.088 | 0.012 | 0.088 | MDM2 inhibitor | |||
| 0.135 | 0.06 | 0.135 | M18 aspartyl aminopeptidase inhibitor | |||
| 0.093 | 0.018 | 0.093 | Carbonic anhydrase VB inhibitor | |||
| 0.081 | 0.006 | 0.179 | Heparanase inhibitor | 0.179 0.002 DBMET00488 | DBMET00488 | |
| 0.08 | 0.006 | 0.1 | Arginase inhibitor | 0.1 0.004 DBMET00488 | DBMET00488 | |
| 0.078 | 0.004 | 0.078 | 3-Hydroxyanthranilate 3,4-dioxygenase inhibitor | 0.044 0.023 DBMET00488 | ||
| 0.081 | 0.007 | 0.081 | AICAR transformylase inhibitor | 0.041 0.037 DBMET00488 | ||
| 0.077 | 0.004 | 0.077 | Tubulin agonist | 0.032 0.031 DBMET00488 | ||
| 0.085 | 0.012 | 0.085 | Opioid kappa receptor agonist | |||
| 0.077 | 0.004 | 0.098 | Uridine phosphorylase inhibitor | 0.098 0.002 DBMET00488 | DBMET00488 | |
| 0.081 | 0.008 | 0.081 | Thymidine kinase inhibitor | 0.062 0.013 DBMET00488 | ||
| 0.076 | 0.005 | 0.076 | Microtubule stabilization | 0.062 0.012 DBMET00488 | ||
| 0.076 | 0.005 | 0.082 | Neuraminidase (Influenza A) inhibitor | 0.082 0.005 DBMET00488 | DBMET00488 | |
| 0.113 | 0.042 | 0.113 | Interleukin 1 beta converting enzyme inhibitor | 0.094 0.065 DBMET00488 | ||
| 0.124 | 0.054 | 0.124 | Caspase 3 inhibitor | |||
| 0.08 | 0.01 | 0.08 | Dihydroorotate oxidase inhibitor | |||
| 0.073 | 0.004 | 0.073 | Prostaglandin D2 agonist | |||
| 0.072 | 0.003 | 0.072 | Ceramide glucosyltransferase inhibitor | 0.047 0.009 DBMET00488 | ||
| 0.097 | 0.029 | 0.097 | CDC25A inhibitor | 0.066 0.063 DBMET00488 | ||
| 0.081 | 0.013 | 0.081 | Purinergic P2Y antagonist | 0.043 0.033 DBMET00488 | ||
| 0.103 | 0.035 | 0.103 | Adrenaline agonist | |||
| 0.083 | 0.015 | 0.083 | Transcription factor RelA inhibitor | |||
| 0.087 | 0.02 | 0.087 | Potassium channel (Tandem pore domain) blocker | |||
| 0.079 | 0.013 | 0.079 | Nicotinic alpha3beta2 receptor antagonist | |||
| 0.071 | 0.005 | 0.071 | Hypoxanthine phosphoribosyltransferase inhibitor | 0.052 0.008 DBMET00488 | ||
| 0.083 | 0.017 | 0.083 | Fatty acid synthase inhibitor | |||
| 0.076 | 0.011 | 0.18 | Adenine nucleotide translocase inhibitor | 0.18 0.003 DBMET00488 | DBMET00488 | |
| 0.067 | 0.002 | 0.067 | Purinergic P2Y15 antagonist | 0.037 0.009 DBMET00488 | ||
| 0.071 | 0.007 | 0.071 | Geranyltranstransferase inhibitor | |||
| 0.208 | 0.143 | 0.208 | 12-Lipoxygenase inhibitor | |||
| 0.088 | 0.024 | 0.088 | NMDA receptor agonist | |||
| 0.071 | 0.007 | 0.071 | Alpha 1d adrenoreceptor agonist | |||
| 0.1 | 0.037 | 0.1 | Inducible nitric-oxide synthase inhibitor | |||
| 0.097 | 0.034 | 0.097 | Nicotinic alpha4beta2 receptor antagonist | |||
| 0.075 | 0.013 | 0.075 | Beta 2 adrenoreceptor agonist | |||
| 0.086 | 0.024 | 0.086 | NMDA receptor glycine site agonist | |||
| 0.12 | 0.058 | 0.161 | DNA intercalator | 0.161 0.038 DBMET00488 | DBMET00488 | |
| 0.092 | 0.029 | 0.092 | Sphingosine 1-phosphate receptor 4 agonist | |||
| 0.09 | 0.028 | 0.09 | Phosphodiesterase VI inhibitor | |||
| 0.09 | 0.029 | 0.09 | Potassium channel large-conductance Ca-activated activator | |||
| 0.143 | 0.082 | 0.198 | Phospholipase A2 inhibitor | 0.198 0.044 DBMET00488 | DBMET00488 | |
| 0.065 | 0.004 | 0.065 | HMG CoA reductase inhibitor | |||
| 0.065 | 0.004 | 0.065 | Vanilloid 3 antagonist | |||
| 0.124 | 0.063 | 0.124 | Acetylcholine muscarinic antagonist | |||
| 0.07 | 0.01 | 0.07 | Cholesterol esterase inhibitor | |||
| 0.077 | 0.017 | 0.131 | Factor IXa inhibitor | 0.131 0.005 DBMET00488 | DBMET00488 | |
| 0.073 | 0.014 | 0.073 | Potassium channel Kv1.3 blocker | |||
| 0.081 | 0.022 | 0.098 | Nitric oxide donor | 0.098 0.01 DBMET00488 | DBMET00488 | |
| 0.127 | 0.068 | 0.127 | MAP kinase kinase inhibitor | |||
| 0.072 | 0.013 | 0.072 | Lysophosphatidic acid 3 receptor antagonist | |||
| 0.07 | 0.012 | 0.07 | Thymidylate synthase inhibitor | |||
| 0.144 | 0.086 | 0.361 | Anticoagulant | 0.361 0.02 DBMET00488 | DBMET00488 | |
| 0.067 | 0.009 | 0.067 | HIV-1 protease inhibitor | |||
| 0.084 | 0.027 | 0.084 | Adenosine A1 receptor antagonist | |||
| 0.076 | 0.02 | 0.076 | Botulinum neurotoxin type A inhibitor | |||
| 0.064 | 0.008 | 0.064 | Prostaglandin agonist | |||
| 0.107 | 0.051 | 0.107 | Protein kinase C mu inhibitor | |||
| 0.082 | 0.026 | 0.082 | Ribonucleotide reductase inhibitor | |||
| 0.064 | 0.009 | 0.064 | Farnesoid X receptor agonist | |||
| 0.102 | 0.047 | 0.102 | Calcium antagonist | |||
| 0.059 | 0.004 | 0.059 | Prostaglandin F2 alpha agonist | 0.023 0.015 DBMET00488 | ||
| 0.063 | 0.009 | 0.063 | GABA uptake inhibitor | |||
| 0.065 | 0.011 | 0.065 | Dopamine beta hydroxylase inhibitor | |||
| 0.057 | 0.002 | 0.064 | Vanilloid 2 agonist | 0.064 0.002 DBMET00488 | DBMET00488 | |
| 0.069 | 0.015 | 0.069 | Aldosterone antagonist | |||
| 0.079 | 0.025 | 0.079 | Ribonucleoside-diphosphate reductase inhibitor | |||
| 0.067 | 0.014 | 0.067 | Immunoglobulin Fc receptor antagonist | |||
| 0.07 | 0.017 | 0.07 | Acetyl-CoA transferase 2 inhibitor | |||
| 0.105 | 0.053 | 0.105 | Nitric-oxide synthase inhibitor | |||
| 0.057 | 0.005 | 0.057 | ATP citrate lysase inhibitor | |||
| 0.083 | 0.032 | 0.083 | Secretase beta inhibitor | |||
| 0.077 | 0.026 | 0.077 | Beta 3 adrenoreceptor antagonist | |||
| 0.055 | 0.004 | 0.055 | Glutamate (mGluR3) agonist | 0.038 0.012 DBMET00488 | ||
| 0.076 | 0.025 | 0.076 | Cyclin-dependent kinase 6 inhibitor | |||
| 0.053 | 0.003 | 0.053 | Hedgehog signaling activator | |||
| 0.054 | 0.004 | 0.054 | Prostacyclin agonist | |||
| 0.058 | 0.008 | 0.058 | Delayed rectifier potassium channel blocker | |||
| 0.073 | 0.024 | 0.073 | Cyclin D1 inhibitor | |||
| 0.077 | 0.03 | 0.077 | Beta adrenoreceptor antagonist | |||
| 0.151 | 0.104 | 0.151 | Catenin beta inhibitor | |||
| 0.116 | 0.069 | 0.116 | Proteasome inhibitor | |||
| 0.053 | 0.007 | 0.053 | CF transmembrane conductance regulator antagonist | |||
| 0.061 | 0.016 | 0.061 | Oxytocin agonist | |||
| 0.05 | 0.004 | 0.05 | S-adenosyl-L-homocysteine hydrolase inhibitor | 0.018 0.007 DBMET00488 | ||
| 0.057 | 0.011 | 0.057 | Membrane dipeptidase inhibitor | |||
| 0.057 | 0.012 | 0.057 | Inosine monophosphate dehydrogenase inhibitor | |||
| 0.046 | 0.001 | 0.046 | Telomerase stimulant | 0.046 0.001 DBMET00488 | ||
| 0.048 | 0.004 | 0.075 | Ileal bile acid transport inhibitor | 0.075 0.003 DBMET00488 | DBMET00488 | |
| 0.075 | 0.031 | 0.075 | Aryl hydrocarbon receptor antagonist | |||
| 0.111 | 0.067 | 0.111 | Nav1.5 sodium channel blocker | |||
| 0.049 | 0.006 | 0.049 | Prostaglandin EP2 agonist | |||
| 0.057 | 0.014 | 0.057 | Parathyroid hormone antagonist | |||
| 0.075 | 0.032 | 0.075 | Protease 3C (Human rhinovirus) inhibitor | |||
| 0.062 | 0.019 | 0.062 | Estradiol 17 beta-dehydrogenase inhibitor | |||
| 0.055 | 0.013 | 0.089 | Squalene synthetase inhibitor | 0.089 0.007 DBMET00488 | DBMET00488 | |
| 0.045 | 0.004 | 0.045 | Thymidine kinase (Herpes simplex virus 1) inhibitor | 0.026 0.021 DBMET00488 | ||
| 0.052 | 0.01 | 0.052 | Glucose-6-phosphate dehydrogenase inhibitor | |||
| 0.051 | 0.009 | 0.051 | Purinergic P2X agonist | |||
| 0.052 | 0.011 | 0.052 | Heme oxygenase inhibitor | |||
| 0.075 | 0.034 | 0.075 | Potassium channel (ATP-sensitive) blocker | |||
| 0.071 | 0.031 | 0.071 | Xanthine dehydrogenase inhibitor | |||
| 0.045 | 0.005 | 0.045 | Thymidine phosphorylase inhibitor | 0.025 0.02 DBMET00488 | ||
| 0.054 | 0.014 | 0.054 | Nerve growth factor antagonist | |||
| 0.064 | 0.024 | 0.064 | Epithelial sodium channel blocker | 0.052 0.043 DBMET00488 | ||
| 0.068 | 0.028 | 0.068 | Beta 1 adrenoreceptor antagonist | |||
| 0.062 | 0.023 | 0.062 | Beta 2 adrenoreceptor antagonist | |||
| 0.05 | 0.011 | 0.05 | 2,3-Oxidosqualene-lanosterol cyclase inhibitor | |||
| 0.072 | 0.033 | 0.072 | Aromatase inhibitor | |||
| 0.055 | 0.016 | 0.055 | Glutamate (mGluR group III) antagonist | |||
| 0.07 | 0.032 | 0.07 | Carbonic anhydrase stimulant | |||
| 0.063 | 0.025 | 0.069 | Leukotriene B4 antagonist | 0.069 0.02 DBMET00488 | DBMET00488 | |
| 0.047 | 0.009 | 0.047 | Cholesterol ester transfer protein antagonist | |||
| 0.102 | 0.064 | 0.102 | Protease inhibitor | 0.088 0.077 DBMET00488 | ||
| 0.189 | 0.152 | 0.189 | Lipoxygenase inhibitor | |||
| 0.041 | 0.004 | 0.041 | 1,3-Beta-glucan synthase inhibitor | 0.037 0.005 DBMET00488 | ||
| 0.044 | 0.007 | 0.044 | Adenosine A1 receptor agonist | 0.025 0.016 DBMET00488 | ||
| 0.04 | 0.002 | 0.04 | Thromboxane A2 agonist | |||
| 0.042 | 0.005 | 0.042 | Vitamin D receptor antagonist | 0.022 0.016 DBMET00488 | ||
| 0.053 | 0.017 | 0.053 | GABA B receptor antagonist | |||
| 0.045 | 0.009 | 0.045 | Tryptophan 5 hydroxylase inhibitor | |||
| 0.04 | 0.003 | 0.04 | Isoleucine-tRNA ligase inhibitor | 0.028 0.007 DBMET00488 | ||
| 0.092 | 0.056 | 0.092 | Phosphodiesterase I inhibitor | |||
| 0.052 | 0.016 | 0.052 | Dihydropteroate synthase inhibitor | |||
| 0.041 | 0.005 | 0.041 | Inosine monophosphate dehydrogenase 1 inhibitor | 0.018 0.016 DBMET00488 | ||
| 0.038 | 0.002 | 0.05 | Antibiotic Anthracycline-like | 0.05 0.002 DBMET00488 | DBMET00488 | |
| 0.055 | 0.019 | 0.055 | Purinergic P2X4 antagonist | |||
| 0.039 | 0.003 | 0.039 | Thymidine kinase (Herpes simplex virus 2) inhibitor | |||
| 0.042 | 0.007 | 0.042 | Adenosine kinase inhibitor | |||
| 0.04 | 0.006 | 0.04 | Prostaglandin EP4 agonist | |||
| 0.069 | 0.034 | 0.069 | NMDA 2C receptor antagonist | |||
| 0.043 | 0.009 | 0.043 | Estrogen-related receptor beta antagonist | |||
| 0.061 | 0.027 | 0.061 | Leukotriene C antagonist | |||
| 0.07 | 0.036 | 0.07 | Adenosine A2a receptor antagonist | |||
| 0.114 | 0.08 | 0.114 | Cholinergic antagonist | |||
| 0.072 | 0.038 | 0.072 | Leukotriene antagonist | 0.058 0.053 DBMET00488 | ||
| 0.078 | 0.045 | 0.078 | Lipase inhibitor | |||
| 0.059 | 0.025 | 0.059 | Prolyl endopeptidase inhibitor | |||
| 0.08 | 0.047 | 0.08 | Analgesic, opioid | |||
| 0.038 | 0.004 | 0.038 | Corticosteroid-like | 0.032 0.006 DBMET00488 | ||
| 0.066 | 0.034 | 0.066 | Corticotropin releasing factor 2 receptor antagonist | |||
| 0.038 | 0.006 | 0.038 | Estrogen-related receptor gamma antagonist | |||
| 0.161 | 0.129 | 0.161 | Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase inhibitor | |||
| 0.042 | 0.01 | 0.042 | 11-Beta-hydroxysteroid dehydrogenase 2 inhibitor | 0.028 0.019 DBMET00488 | ||
| 0.056 | 0.024 | 0.056 | HCV NS3/NS4A protease inhibitor | |||
| 0.057 | 0.026 | 0.057 | Potassium channel (Inward rectifier) blocker | |||
| 0.054 | 0.022 | 0.054 | NMDA receptor subunit 3B antagonist | |||
| 0.038 | 0.008 | 0.038 | Prostaglandin E2 agonist | |||
| 0.062 | 0.032 | 0.062 | Acetylcholine muscarinic agonist | |||
| 0.036 | 0.007 | 0.036 | Lysophosphatidic acid receptor 1 agonist | |||
| 0.033 | 0.004 | 0.033 | Neuraminidase (Influenza B) inhibitor | 0.025 0.008 DBMET00488 | ||
| 0.032 | 0.003 | 0.032 | Glutamate (mGluR6) agonist | 0.011 0.01 DBMET00488 | ||
| 0.052 | 0.023 | 0.052 | Carbonic anhydrase IV inhibitor | |||
| 0.041 | 0.012 | 0.041 | Protein kinase (CK2) beta inhibitor | |||
| 0.038 | 0.01 | 0.038 | Methionyl aminopeptidase 2 inhibitor | |||
| 0.032 | 0.003 | 0.032 | Purinergic P2Y1 agonist | 0.016 0.01 DBMET00488 | ||
| 0.109 | 0.081 | 0.109 | Acetylcholine antagonist | |||
| 0.038 | 0.009 | 0.038 | Purinergic P2Y12 antagonist | |||
| 0.051 | 0.023 | 0.051 | Glutamate (mGluR group III) agonist | |||
| 0.033 | 0.005 | 0.033 | Glucocorticoid agonist | |||
| 0.049 | 0.021 | 0.049 | Beta adrenoreceptor agonist | |||
| 0.083 | 0.055 | 0.083 | Caspase 7 inhibitor | |||
| 0.044 | 0.016 | 0.044 | Integrin alpha2 antagonist | |||
| 0.068 | 0.041 | 0.096 | Carbonic anhydrase inhibitor | 0.096 0.028 DBMET00488 | DBMET00488 | |
| 0.029 | 0.003 | 0.029 | Methylmalonyl-CoA mutase inhibitor | 0.022 0.006 DBMET00488 | ||
| 0.055 | 0.028 | 0.055 | Bombesin 2 receptor antagonist | |||
| 0.053 | 0.027 | 0.06 | Factor III inhibitor | 0.06 0.017 DBMET00488 | DBMET00488 | |
| 0.031 | 0.004 | 0.031 | Carbonic anhydrase VIII inhibitor | |||
| 0.031 | 0.004 | 0.031 | Carbonic anhydrase X inhibitor | |||
| 0.036 | 0.01 | 0.036 | Estradiol 17 beta-dehydrogenase 1 inhibitor | |||
| 0.115 | 0.089 | 0.115 | Nav1.2 sodium channel blocker | |||
| 0.033 | 0.007 | 0.033 | Glutamate (mGluR1a) agonist | |||
| 0.04 | 0.015 | 0.04 | Acetylcholine M4 receptor agonist | |||
| 0.029 | 0.003 | 0.029 | Thromboxane agonist | |||
| 0.051 | 0.026 | 0.051 | Carbonic anhydrase VII inhibitor | |||
| 0.066 | 0.04 | 0.066 | 5 Hydroxytryptamine 3 agonist | |||
| 0.046 | 0.021 | 0.046 | Plasmepsin II inhibitor | |||
| 0.03 | 0.005 | 0.03 | Cyclin T1 inhibitor | |||
| 0.039 | 0.014 | 0.039 | Adenosine uptake inhibitor | |||
| 0.034 | 0.009 | 0.034 | Nicotinic acid receptor 2 antagonist | |||
| 0.037 | 0.012 | 0.037 | Nicotinic alpha3beta4 receptor agonist | |||
| 0.04 | 0.016 | 0.04 | Estradiol 17 beta-dehydrogenase 3 inhibitor | |||
| 0.046 | 0.022 | 0.046 | NMDA receptor subunit 3A antagonist | |||
| 0.086 | 0.063 | 0.086 | Bromodomain-containing protein 2 inhibitor | |||
| 0.061 | 0.037 | 0.061 | Sphingosine 1-phosphate receptor 3 antagonist | |||
| 0.044 | 0.021 | 0.044 | 5-Alpha-reductase inhibitor | |||
| 0.062 | 0.039 | 0.062 | Acetylcholine M3 receptor antagonist | |||
| 0.031 | 0.008 | 0.031 | Leukotriene B4 receptor 2 antagonist | 0.03 0.009 DBMET00488 | ||
| 0.028 | 0.006 | 0.028 | Adenosine A2a receptor agonist | |||
| 0.063 | 0.04 | 0.066 | Transcription factor AP-1 inhibitor | 0.066 0.035 DBMET00488 | DBMET00488 | |
| 0.033 | 0.01 | 0.033 | Integrin alpha2beta1 antagonist | |||
| 0.032 | 0.009 | 0.032 | Glucosylceramidase stimulant | |||
| 0.059 | 0.036 | 0.072 | Carbonic anhydrase II inhibitor | 0.072 0.029 DBMET00488 | DBMET00488 | |
| 0.039 | 0.017 | 0.039 | Free fatty acid receptor 1 antagonist | |||
| 0.041 | 0.019 | 0.041 | Retinoid X alpha receptor agonist | |||
| 0.037 | 0.014 | 0.037 | Lysophosphatidic acid 2 receptor antagonist | |||
| 0.035 | 0.013 | 0.035 | Lysine carboxypeptidase inhibitor | |||
| 0.064 | 0.043 | 0.064 | 5 Hydroxytryptamine 2A agonist | |||
| 0.047 | 0.025 | 0.047 | Glutamate (mGluR4) antagonist | |||
| 0.056 | 0.034 | 0.056 | Alpha tubulin antagonist | |||
| 0.086 | 0.065 | 0.086 | Pim-3 kinase inhibitor | |||
| 0.042 | 0.021 | 0.042 | Diamine oxidase inhibitor | |||
| 0.025 | 0.004 | 0.025 | Lysophosphatidic acid receptor 3 agonist | |||
| 0.043 | 0.022 | 0.043 | AMPA 4 receptor antagonist | |||
| 0.047 | 0.027 | 0.047 | Acetylcholine M1 receptor agonist | |||
| 0.061 | 0.041 | 0.061 | Acetylcholine M5 receptor antagonist | |||
| 0.026 | 0.006 | 0.026 | Adenosine A3 receptor agonist | |||
| 0.057 | 0.037 | 0.069 | Carbonic anhydrase I inhibitor | 0.069 0.029 DBMET00488 | DBMET00488 | |
| 0.044 | 0.025 | 0.044 | Liver X receptor alpha agonist | |||
| 0.077 | 0.058 | 0.077 | Acetylcholine nicotinic antagonist | |||
| 0.041 | 0.022 | 0.041 | Retinoid X receptor antagonist | |||
| 0.03 | 0.011 | 0.063 | Toll-Like receptor 4 agonist | 0.063 0.003 DBMET00488 | DBMET00488 | |
| 0.025 | 0.006 | 0.025 | Adenosine A2 receptor agonist | 0.016 0.011 DBMET00488 | ||
| 0.045 | 0.027 | 0.045 | Histamine H1 receptor agonist | |||
| 0.035 | 0.016 | 0.035 | Plasmepsin I inhibitor | |||
| 0.045 | 0.027 | 0.045 | Histamine H2 receptor agonist | |||
| 0.07 | 0.053 | 0.07 | Cathepsin G inhibitor | |||
| 0.04 | 0.023 | 0.04 | Retinoid X receptor agonist | |||
| 0.052 | 0.035 | 0.052 | Thromboxane A2 antagonist | |||
| 0.041 | 0.024 | 0.041 | Glutamate (mGluR group II) antagonist | |||
| 0.051 | 0.034 | 0.051 | CD45 antagonist | |||
| 0.022 | 0.005 | 0.022 | Vitamin D receptor agonist | 0.017 0.011 DBMET00488 | ||
| 0.02 | 0.004 | 0.02 | Antibiotic Tetracycline-like | |||
| 0.023 | 0.006 | 0.023 | Nicotinic acid receptor 1 antagonist | |||
| 0.083 | 0.067 | 0.083 | Interleukin-1 receptor-associated protein kinase 4 inhibitor | |||
| 0.045 | 0.03 | 0.045 | Dihydroorotase inhibitor | |||
| 0.036 | 0.02 | 0.036 | Retinoid X alpha receptor antagonist | |||
| 0.03 | 0.015 | 0.03 | Kynurenine 3 monooxygenase inhibitor | |||
| 0.04 | 0.025 | 0.04 | Leukotriene C4 antagonist | |||
| 0.035 | 0.02 | 0.035 | Protein kinase C beta I inhibitor | 0.034 0.022 DBMET00488 | ||
| 0.054 | 0.04 | 0.103 | Carbonic anhydrase IX inhibitor | 0.103 0.019 DBMET00488 | DBMET00488 | |
| 0.056 | 0.042 | 0.056 | Dopamine uptake inhibitor | |||
| 0.08 | 0.066 | 0.08 | NMDA receptor antagonist | |||
| 0.027 | 0.013 | 0.027 | Glutamate (mGluR1) agonist | |||
| 0.027 | 0.013 | 0.027 | Complement factor 1s inhibitor | |||
| 0.055 | 0.041 | 0.055 | 5 Hydroxytryptamine 7 agonist | |||
| 0.04 | 0.026 | 0.04 | Vascular adhesion protein 1 inhibitor | |||
| 0.079 | 0.065 | 0.079 | Thioredoxin reductase inhibitor | |||
| 0.053 | 0.039 | 0.053 | Thromboxane antagonist | |||
| 0.036 | 0.022 | 0.036 | RNA-directed RNA polymerase inhibitor | |||
| 0.02 | 0.007 | 0.023 | Purinergic P2 agonist | 0.023 0.006 DBMET00488 | DBMET00488 | |
| 0.02 | 0.007 | 0.023 | Purinergic receptor agonist | 0.023 0.006 DBMET00488 | DBMET00488 | |
| 0.051 | 0.038 | 0.136 | Carbonic anhydrase XII inhibitor | 0.136 0.014 DBMET00488 | DBMET00488 | |
| 0.068 | 0.055 | 0.068 | Epoxide hydrolase inhibitor | |||
| 0.061 | 0.048 | 0.061 | Adenosine A2 receptor antagonist | |||
| 0.053 | 0.04 | 0.053 | Maillard reaction inhibitor | |||
| 0.037 | 0.024 | 0.037 | Nicotinic acid receptor agonist | |||
| 0.076 | 0.064 | 0.076 | Opioid kappa receptor antagonist | |||
| 0.069 | 0.057 | 0.069 | Metalloproteinase-9 inhibitor | |||
| 0.021 | 0.009 | 0.021 | Alpha 2a adrenoreceptor agonist | |||
| 0.017 | 0.005 | 0.017 | 1-Deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor | |||
| 0.022 | 0.01 | 0.022 | Retinoid X beta receptor antagonist | |||
| 0.032 | 0.02 | 0.032 | HCV NS5B polymerase inhibitor | |||
| 0.019 | 0.007 | 0.023 | Antibiotic Macrolide-like | 0.023 0.006 DBMET00488 | DBMET00488 | |
| 0.058 | 0.046 | 0.058 | Potassium channel intermediate-conductance Ca-activated blocker | |||
| 0.015 | 0.003 | 0.021 | Purinergic P2Y2 agonist | 0.021 0.002 DBMET00488 | DBMET00488 | |
| 0.028 | 0.017 | 0.028 | Prostaglandin EP4 antagonist | |||
| 0.034 | 0.023 | 0.034 | Calcitonin receptor agonist | |||
| 0.032 | 0.021 | 0.032 | Potassium channel small-conductance Ca-activated activator | |||
| 0.033 | 0.022 | 0.033 | Catechol O-methyltransferase inhibitor | |||
| 0.061 | 0.05 | 0.061 | Prolactin release inhibitor | |||
| 0.015 | 0.004 | 0.015 | Purine nucleoside phosphorylase inhibitor | |||
| 0.066 | 0.055 | 0.066 | NMDA 2 receptor antagonist | |||
| 0.04 | 0.029 | 0.04 | Kainate receptor antagonist | |||
| 0.017 | 0.007 | 0.017 | Adenosine A2b receptor agonist | |||
| 0.053 | 0.043 | 0.053 | MAP kinase kinase 9 inhibitor | |||
| 0.022 | 0.012 | 0.022 | Inosine monophosphate dehydrogenase 2 inhibitor | |||
| 0.048 | 0.038 | 0.048 | Diacylglycerol O-acyltransferase inhibitor | |||
| 0.022 | 0.012 | 0.022 | Steroid 17-alpha-hydroxylase/17,20 lyase inhibitor | |||
| 0.027 | 0.017 | 0.027 | Thyroid hormone agonist | |||
| 0.024 | 0.014 | 0.024 | CYP24 inhibitor | |||
| 0.028 | 0.019 | 0.028 | LFA antagonist | |||
| 0.037 | 0.028 | 0.037 | Potassium channel Kv1.1 blocker | |||
| 0.032 | 0.023 | 0.032 | Methionyl aminopeptidase 1 inhibitor | |||
| 0.015 | 0.007 | 0.018 | Purinergic P2Y agonist | 0.018 0.005 DBMET00488 | DBMET00488 | |
| 0.059 | 0.051 | 0.059 | Phosphodiesterase 1C inhibitor | |||
| 0.017 | 0.009 | 0.017 | NMDA receptor phencyclidine site antagonist | |||
| 0.026 | 0.018 | 0.026 | Prostaglandin H2 antagonist | |||
| 0.056 | 0.048 | 0.056 | Alpha 2 adrenoreceptor agonist | |||
| 0.032 | 0.025 | 0.032 | Carboxypeptidase B inhibitor | |||
| 0.052 | 0.044 | 0.052 | Thromboxane synthase inhibitor | |||
| 0.053 | 0.045 | 0.053 | Sphingosine 1-phosphate receptor 1 antagonist | |||
| 0.034 | 0.027 | 0.034 | Kainate receptor 2 antagonist | |||
| 0.023 | 0.016 | 0.023 | ICAM 1 antagonist | |||
| 0.121 | 0.115 | 0.121 | Thiol protease inhibitor | |||
| 0.01 | 0.004 | 0.01 | DNA topoisomerase III inhibitor | |||
| 0.022 | 0.016 | 0.024 | Dopamine D1 agonist | 0.024 0.014 DBMET00488 | DBMET00488 | |
| 0.03 | 0.024 | 0.03 | Glucocorticoid antagonist | |||
| 0.019 | 0.013 | 0.019 | Estrogen-related receptor gamma agonist | |||
| 0.008 | 0.003 | 0.008 | Transcortin receptor antagonist | |||
| 0.021 | 0.015 | 0.021 | Lysophosphatidic acid 1 receptor antagonist | |||
| 0.013 | 0.008 | 0.013 | Carbonic anhydrase XI inhibitor | |||
| 0.048 | 0.043 | 0.048 | 5 Hydroxytryptamine 4 antagonist | |||
| 0.034 | 0.029 | 0.034 | Glutamate (mGluR8) antagonist | 0.033 0.032 DBMET00488 | ||
| 0.027 | 0.022 | 0.027 | Nicotinic alpha4beta2 receptor agonist | |||
| 0.071 | 0.067 | 0.071 | Sphingosine 1-phosphate receptor antagonist | |||
| 0.028 | 0.024 | 0.028 | Glutamate (mGluR2) antagonist | |||
| 0.025 | 0.022 | 0.028 | Leukotriene B4 receptor 1 antagonist | 0.028 0.02 DBMET00488 | DBMET00488 | |
| 0.019 | 0.016 | 0.019 | Kainate receptor 1 antagonist | |||
| 0.018 | 0.015 | 0.018 | 5-Alpha-reductase 2 inhibitor | |||
| 0.035 | 0.032 | 0.035 | Urate transporter 1 inhibitor | |||
| 0.007 | 0.004 | 0.007 | Integrin alpha5beta6 antagonist | |||
| 0.036 | 0.033 | 0.036 | 5 Hydroxytryptamine 2B agonist | |||
| 0.011 | 0.008 | 0.011 | Calcineurin inhibitor | |||
| 0.036 | 0.033 | 0.036 | MAP3K5 inhibitor | |||
| 0.108 | 0.105 | 0.108 | Toll-Like receptor antagonist | |||
| 0.035 | 0.032 | 0.035 | DNA gyrase subunit B inhibitor | |||
| 0.013 | 0.01 | 0.013 | Cyclin D2 inhibitor | |||
| 0.018 | 0.015 | 0.018 | Alpha 2b adrenoreceptor agonist | |||
| 0.162 | 0.16 | 0.162 | Calpain inhibitor | |||
| 0.008 | 0.006 | 0.008 | Mannitol 2-dehydrogenase inhibitor | |||
| 0.09 | 0.088 | 0.094 | Folate antagonist | 0.094 0.078 DBMET00488 | DBMET00488 | |
| 0.024 | 0.022 | 0.024 | CXC chemokine 2 receptor antagonist | |||
| 0.009 | 0.007 | 0.009 | Progesterone receptor A antagonist | |||
| 0.013 | 0.012 | 0.013 | Integrin alphaVbeta6 antagonist | |||
| 0.046 | 0.045 | 0.046 | Opioid agonist | |||
| 0.038 | 0.037 | 0.038 | Sphingosine 1-phosphate receptor 1 agonist | |||
| 0.049 | 0.048 | 0.049 | Lysine-specific demethylase 1A inhibitor | |||
| 0.003 | 0.002 | 0.004 | Purinergic P2Y6 agonist | 0.004 0.002 DBMET00488 | DBMET00488 | |
| 0.018 | 0.026 | 0.022 | Motilin receptor agonist | 0.022 0.017 DBMET00488 | DBMET00488 | |
| 0.013 | 0.025 | 0.02 | O6-alkylguanine-DNA alkyltransferase inhibitor | 0.02 0.007 DBMET00488 | DBMET00488 | |
| 0.077 | 0.133 | 0.181 | Cyclooxygenase 1 inhibitor | 0.181 0.043 DBMET00488 | DBMET00488 | |
| 0.014 | 0.076 | 0.085 | Caspase 2 inhibitor | 0.085 0.005 DBMET00488 | DBMET00488 | |
| 0.126 | 0.278 | 0.311 | Angiogenesis inhibitor | 0.311 0.087 DBMET00488 | DBMET00488 | |
| 0.045 | 0.284 | 0.136 | Cyclooxygenase inhibitor | 0.136 0.082 DBMET00488 | DBMET00488 | |
| 0.035 | 0.312 | 0.146 | Multidrug resistance-associated protein 1 inhibitor | 0.146 0.027 DBMET00488 | DBMET00488 | |
| 0.029 | 0.355 | 0.103 | Cyclooxygenase 2 inhibitor | 0.103 0.101 DBMET00488 | DBMET00488 | |
| 0.005 | 0.697 | 0.03 | Caspase 6 inhibitor | 0.03 0.023 DBMET00488 | DBMET00488 | Ext | Pa | Pi | Pmax | Activity | Other Results | ID Pa_max |