List of predicted activities

List of Predicted Activities

No - number of activity
Active compounds - number of active compounds
IAP - Invariant accuracy of prediction

This is Activities List for PASS Online

No	Activity Type	Active compounds	IAP
1	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase inhibitor	6	0.9555
2	(R)-3-amino-2-methylpropionate-pyruvate transaminase inhibitor	24	0.9969
3	(R)-6-hydroxynicotine oxidase inhibitor	3	0.9296
4	(R)-aminopropanol dehydrogenase inhibitor	10	0.9906
5	(R)-limonene 6-monooxygenase inhibitor	3	0.9969
6	(R)-Pantolactone dehydrogenase (flavin) inhibitor	8	0.8724
7	(R,R)-butanediol dehydrogenase inhibitor	3	0.9947
8	(S)-2-hydroxy-acid oxidase inhibitor	28	0.9258
9	(S)-2-Methylmalate dehydratase inhibitor	4	0.9965
10	(S)-3-amino-2-methylpropionate transaminase inhibitor	8	0.9543
11	(S)-3-hydroxyacid ester dehydrogenase inhibitor	3	0.9908
12	(S)-6-hydroxynicotine oxidase inhibitor	4	0.9526
13	(S)-carnitine 3-dehydrogenase inhibitor	7	0.9877
14	(S)-methylmalonyl-CoA hydrolase inhibitor	8	1.0000
15	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase inhibitor	34	0.9919
16	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase inhibitor	12	0.9998
17	[acetyl-CoA carboxylase] kinase inhibitor	6	0.9955
18	[acyl-carrier-protein] S-acetyltransferase inhibitor	7	0.9562
19	[acyl-carrier-protein] S-malonyltransferase inhibitor	10	0.9873
20	[citrate-(pro-3S)-lyase] thiolesterase inhibitor	4	0.9992
21	[glutamate-ammonia-ligase] adenylyltransferase inhibitor	13	0.9971
22	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitor	11	0.9555
23	[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase inhibitor	8	0.9981
24	[Isocitrate dehydrogenase (NADP+)] kinase inhibitor	9	0.9979
25	[myelin basic protein]-arginine N-methyltransferase inhibitor	3	0.9841
26	[phosphorylase] phosphatase inhibitor	14	0.9449
27	[protein-PII] uridylyltransferase inhibitor	27	0.9973
28	[Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase inhibitor	5	0.9974
29	1,2-alpha-L-fucosidase inhibitor	5	0.9483
30	1,3-Beta-glucan synthase inhibitor	3	0.9992
31	1,4-Alpha-glucan branching enzyme inhibitor	4	0.9592
32	1,4-Lactonase inhibitor	4	0.8081
33	1,5-Anhydro-D-fructose reductase inhibitor	9	0.9925
34	11-Beta-hydroxysteroid dehydrogenase 1 inhibitor	1737	0.9921
35	11-Beta-hydroxysteroid dehydrogenase 2 inhibitor	253	0.9977
36	11-Beta-hydroxysteroid dehydrogenase inhibitor	1789	0.9917
37	11-Cis-retinyl-palmitate hydrolase inhibitor	4	0.9960
38	12-Lipoxygenase inhibitor	86	0.9768
39	15-Hydroxyprostaglandin-D dehydrogenase (NADP+) inhibitor	8	0.9686
40	15-Lipoxygenase inhibitor	269	0.9827
41	17-Beta-hydroxysteroid dehydrogenase 1 inhibitor	49	0.9816
42	17-Beta-hydroxysteroid dehydrogenase 5 inhibitor	6	1.0000
43	1-Acylglycerol-3-phosphate O-acyltransferase inhibitor	45	0.8821
44	1-Alkyl-2-acetylglycerol O-acyltransferase inhibitor	3	0.9979
45	1-Alkyl-2-acetylglycerophosphocholine esterase inhibitor	441	0.9926
46	1-Alkylglycerophosphocholine O-acetyltransferase inhibitor	24	0.9261
47	1-Aminocyclopropane-1-carboxylate deaminase inhibitor	11	0.9876
48	1-Deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor	12	0.9982
49	1-Phosphofructokinase inhibitor	9	0.9905
50	1-Pyrroline-5-carboxylate dehydrogenase inhibitor	24	0.9895
51	2-(acetamidomethylene)succinate hydrolase inhibitor	11	0.9991
52	2,2-Dialkylglycine decarboxylase (pyruvate) inhibitor	7	0.9888
53	2,3,4,5-Tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase inhibitor	5	0.9715
54	2,3-Dihydroxyindole 2,3-dioxygenase inhibitor	4	0.9852
55	2,3-Oxidosqualene-lanosterol cyclase inhibitor	142	0.9882
56	2,4-Diaminopentanoate dehydrogenase inhibitor	3	0.9896
57	2,4-Dichlorophenol 6-monooxygenase inhibitor	9	0.9714
58	2,5-Dihydroxypyridine 5,6-dioxygenase inhibitor	7	0.9896
59	2,6-Dihydroxypyridine 3-monooxygenase inhibitor	3	0.9829
60	27-Hydroxycholesterol 7alpha-monooxygenase inhibitor	6	0.8289
61	2-Acylglycerol O-acyltransferase inhibitor	18	0.9388
62	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase inhibitor	4	0.9987
63	2-Aminoadipate transaminase inhibitor	6	0.9850
64	2-Aminoethylphosphonate-pyruvate transaminase inhibitor	9	0.9906
65	2-Aminohexano-6-lactam racemase inhibitor	19	0.9847
66	2-Aminohexanoate transaminase inhibitor	3	1.0000
67	2-Dehydro-3-deoxy-L-arabinonate dehydratase inhibitor	4	0.9936
68	2-Dehydro-3-deoxy-phosphogluconate aldolase inhibitor	6	0.9916
69	2-Dehydropantoate 2-reductase inhibitor	7	0.8106
70	2-Dehydropantoate aldolase inhibitor	3	0.9918
71	2-Dehydropantolactone reductase (A-specific) inhibitor	10	0.9909
72	2-Enoate reductase inhibitor	10	0.9618
73	2-Ethylmalate synthase inhibitor	3	0.9996
74	2-Haloacid dehalogenase (configuration-inverting) inhibitor	6	0.9858
75	2-Haloacid dehalogenase inhibitor	3	0.9735
76	2-Hydroxy-3-oxoadipate synthase inhibitor	3	0.9827
77	2-Hydroxy-3-oxopropionate reductase inhibitor	5	0.9904
78	2-Hydroxyacylsphingosine 1-beta-galactosyltransferase inhibitor	3	1.0000
79	2-Hydroxymuconate-semialdehyde hydrolase inhibitor	7	0.9331
80	2-Hydroxyquinoline 8-monooxygenase inhibitor	6	0.8414
81	2-Isopropylmalate synthase inhibitor	15	0.9984
82	2-Methylacyl-CoA dehydrogenase inhibitor	7	0.9850
83	2-Methyl-branched-chain-enoyl-CoA reductase inhibitor	5	0.9799
84	2-Methylcitrate dehydratase inhibitor	4	0.9963
85	2-Methylcitrate synthase inhibitor	3	0.9781
86	2-Methyleneglutarate mutase inhibitor	9	0.9916
87	2-Nitrophenol 2-monooxygenase inhibitor	3	0.9904
88	2-Nitropropane dioxygenase inhibitor	21	0.9676
89	2-Oxoaldehyde dehydrogenase (NAD+) inhibitor	12	0.9910
90	2-Oxoaldehyde dehydrogenase (NADP+) inhibitor	3	0.9851
91	2-Oxoglutarate decarboxylase inhibitor	8	0.9824
92	2-Oxoisovalerate dehydrogenase (acylating) inhibitor	4	0.9923
93	2-Pyrocatechuate decarboxylase inhibitor	20	0.9919
94	3 Beta-hydroxy-delta 5-steroid dehydrogenase inhibitor	97	0.9997
95	3'(2'),5'-Bisphosphate nucleotidase inhibitor	4	0.9967
96	3(or 17)alpha-hydroxysteroid dehydrogenase inhibitor	9	0.9927
97	3(or 17)beta-hydroxysteroid dehydrogenase inhibitor	63	0.9772
98	3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase inhibitor	4	0.9857
99	3,4-Dihydroxyphenylacetate 2,3-dioxygenase inhibitor	12	0.9960
100	3-Alpha-hydroxysteroid dehydrogenase (B-specific) inhibitor	7	0.9734
101	3-Aminobutyryl-CoA ammonia-lyase inhibitor	3	0.9936
102	3-Carboxyethylcatechol 2,3-dioxygenase inhibitor	4	0.9889
103	3-Chloro-D-alanine dehydrochlorinase inhibitor	4	0.9878
104	3C-like protease (Human coronavirus) inhibitor	29	0.8891
105	3-Cyanoalanine hydratase inhibitor	4	0.8386
106	3-Dehydroquinate dehydratase inhibitor	14	0.9940
107	3-Dehydroquinate synthase inhibitor	16	0.9948
108	3'-Demethylstaurosporine O-methyltransferase inhibitor	4	0.9694
109	3-Demethylubiquinone-9 3-O-methyltransferase inhibitor	3	0.9861
110	3-Deoxy-7-phosphoheptulonate synthase inhibitor	48	0.9917
111	3-Deoxy-8-phosphooctulonate synthase inhibitor	8	0.9948
112	3-Galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase inhibitor	3	0.9936
113	3-Hydroxy-4-oxoquinoline 2,4-dioxygenase inhibitor	6	0.9808
114	3-Hydroxyacyl-CoA dehydrogenase inhibitor	6	0.9908
115	3-Hydroxyanthranilate 3,4-dioxygenase inhibitor	14	0.9456
116	3-Hydroxyanthranilate oxidase inhibitor	13	0.9804
117	3-Hydroxybenzoate 4-monooxygenase inhibitor	7	0.9809
118	3-Hydroxybenzoate 6-monooxygenase inhibitor	5	0.8427
119	3-Hydroxybutyrate dehydrogenase inhibitor	25	0.9900
120	3-Hydroxybutyryl-CoA dehydrogenase inhibitor	3	0.9896
121	3-Hydroxydecanoyl-[acyl-carrier-protein] dehydratase inhibitor	9	0.9895
122	3-Hydroxyisobutyryl-CoA hydrolase inhibitor	7	1.0000
123	3-Hydroxyphenylacetate 6-hydroxylase inhibitor	4	0.9906
124	3-Isopropylmalate dehydratase inhibitor	8	0.9862
125	3-Isopropylmalate dehydrogenase inhibitor	7	0.9956
126	3-Ketovalidoxylamine C-N-lyase inhibitor	4	0.9849
127	3-Mercaptopyruvate sulfurtransferase inhibitor	9	0.9997
128	3-Methyl-2-oxobutanoate dehydrogenase (lipoamide) inhibitor	15	0.9953
129	3-Methyl-2-oxobutanoate hydroxymethyltransferase inhibitor	8	0.9816
130	3-Methylbutanal reductase inhibitor	9	0.8575
131	3'-Nucleotidase inhibitor	8	0.9780
132	3-Oxoacid CoA-transferase inhibitor	26	0.9933
133	3-Oxoacyl-[acyl-carrier-protein] synthase II inhibitor	9	0.9838
134	3-Oxoacyl-[acyl-carrier-protein] synthase III inhibitor	32	0.9806
135	3-Oxoacyl-[acyl-carrier-protein] synthase inhibitor	54	0.9835
136	3-Oxoadipate enol-lactonase inhibitor	3	0.9928
137	3-Oxosteroid 1-dehydrogenase inhibitor	6	0.9944
138	3-Phosphoshikimate 1-carboxyvinyltransferase inhibitor	41	0.9971
139	3-Phytase inhibitor	9	0.8882
140	4,5-Dihydroxyphthalate decarboxylase inhibitor	16	0.9304
141	4a-Hydroxytetrahydrobiopterin dehydratase inhibitor	3	0.9983
142	4-Alpha-glucanotransferase inhibitor	8	0.9915
143	4-Carboxymethyl-4-methylbutenolide mutase inhibitor	9	0.9946
144	4-Chlorobenzoyl-CoA dehalogenase inhibitor	7	0.9771
145	4-Chlorophenylacetate 3,4-dioxygenase inhibitor	4	0.9876
146	4-Coumarate-CoA ligase inhibitor	8	0.8520
147	4-Hydroxy-2-oxoglutarate aldolase inhibitor	17	0.9946
148	4-Hydroxy-4-methyl-2-oxoglutarate aldolase inhibitor	11	0.9954
149	4-Hydroxybenzoate 1-hydroxylase inhibitor	3	0.9995
150	4-Hydroxybenzoate 3-monooxygenase [NAD(P)H] inhibitor	6	0.9998
151	4-Hydroxybenzoate 3-monooxygenase inhibitor	28	0.9858
152	4-Hydroxybenzoate decarboxylase inhibitor	7	0.9973
153	4-Hydroxybenzoate nonaprenyltransferase inhibitor	15	0.9661
154	4-Hydroxybenzoate-CoA ligase inhibitor	4	0.9980
155	4-Hydroxyglutamate transaminase inhibitor	4	0.9857
156	4-Hydroxymandelate oxidase inhibitor	10	0.9266
157	4-Hydroxyphenylacetate 1-monooxygenase inhibitor	4	0.9998
158	4-Hydroxyphenylacetate 3-monooxygenase inhibitor	8	0.8789
159	4-Hydroxyphenylpyruvate dioxygenase inhibitor	22	0.9950
160	4-Hydroxyproline epimerase inhibitor	8	0.8755
161	4-Methoxybenzoate monooxygenase (O-demethylating) inhibitor	19	0.8921
162	4-Nitrophenol 2-monooxygenase inhibitor	6	0.8201
163	4-Nitrophenylphosphatase inhibitor	47	0.8961
164	4-Phytase inhibitor	13	0.9856
165	4-Pyridoxolactonase inhibitor	6	0.9941
166	5 Hydroxytryptamine 1 agonist	1903	0.9865
167	5 Hydroxytryptamine 1 antagonist	4787	0.9821
168	5 Hydroxytryptamine 1A agonist	1131	0.9884
169	5 Hydroxytryptamine 1A antagonist	3853	0.9851
170	5 Hydroxytryptamine 1B agonist	65	0.9897
171	5 Hydroxytryptamine 1B antagonist	1027	0.9860
172	5 Hydroxytryptamine 1D agonist	695	0.9955
173	5 Hydroxytryptamine 1D antagonist	1072	0.9853
174	5 Hydroxytryptamine 1E antagonist	33	0.9108
175	5 Hydroxytryptamine 1F agonist	115	0.9993
176	5 Hydroxytryptamine 1F antagonist	216	0.9899
177	5 Hydroxytryptamine 2 agonist	479	0.9912
178	5 Hydroxytryptamine 2 antagonist	4227	0.9738
179	5 Hydroxytryptamine 2A agonist	59	0.9501
180	5 Hydroxytryptamine 2A antagonist	2961	0.9809
181	5 Hydroxytryptamine 2B agonist	9	0.9469
182	5 Hydroxytryptamine 2B antagonist	861	0.9782
183	5 Hydroxytryptamine 2C agonist	415	0.9951
184	5 Hydroxytryptamine 2C antagonist	1781	0.9847
185	5 Hydroxytryptamine 3 agonist	73	0.9691
186	5 Hydroxytryptamine 3 antagonist	1679	0.9888
187	5 Hydroxytryptamine 3A antagonist	254	0.9771
188	5 Hydroxytryptamine 4 agonist	343	0.9945
189	5 Hydroxytryptamine 4 antagonist	571	0.9945
190	5 Hydroxytryptamine 4A antagonist	7	0.9353
191	5 Hydroxytryptamine 4B antagonist	6	0.9994
192	5 Hydroxytryptamine 4C antagonist	4	0.9777
193	5 Hydroxytryptamine 4D antagonist	4	0.9777
194	5 Hydroxytryptamine 4E antagonist	27	0.9951
195	5 Hydroxytryptamine 5 antagonist	126	0.9836
196	5 Hydroxytryptamine 5A antagonist	124	0.9851
197	5 Hydroxytryptamine 6 agonist	29	0.9919
198	5 Hydroxytryptamine 6 antagonist	764	0.9914
199	5 Hydroxytryptamine 7 agonist	8	0.9261
200	5 Hydroxytryptamine 7 antagonist	560	0.9838
201	5 Hydroxytryptamine 7L antagonist	5	0.9513
202	5 Hydroxytryptamine 7S antagonist	5	0.9462
203	5 Hydroxytryptamine agonist	2906	0.9786
204	5 Hydroxytryptamine antagonist	10856	0.9662
205	5 Hydroxytryptamine release inhibitor	33	0.8710
206	5 Hydroxytryptamine release stimulant	17	0.9117
207	5 Hydroxytryptamine uptake inhibitor	4311	0.9852
208	5 Hydroxytryptamine uptake stimulant	5	0.8135
209	5 Lipoxygenase activating protein inhibitor	144	0.9996
210	5-Alpha-reductase 1 inhibitor	467	0.9963
211	5-Alpha-reductase 2 inhibitor	509	0.9934
212	5-Alpha-reductase inhibitor	1463	0.9941
213	5-Aminolevulinate synthase inhibitor	25	0.9788
214	5-Aminovalerate transaminase inhibitor	7	0.9965
215	5-Formyltetrahydrofolate cyclo-ligase inhibitor	11	0.9297
216	5-Guanidino-2-oxopentanoate decarboxylase inhibitor	8	0.9999
217	5-Hydroxypentanoate CoA-transferase inhibitor	4	0.9998
218	5-Lipoxygenase inhibitor	1998	0.9832
219	5-Methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase inhibitor	4	0.9959
220	5'-Nucleotidase inhibitor	45	0.9944
221	5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase inhibitor	3	0.8822
222	5-Oxoprolinase (ATP-hydrolysing) inhibitor	8	0.9958
223	6,7-Dihydropteridine reductase inhibitor	47	0.9746
224	6-Carboxyhexanoate-CoA ligase inhibitor	3	0.9894
225	6-Methylsalicylate decarboxylase inhibitor	8	0.9891
226	6-Phospho-beta-glucosidase inhibitor	8	0.9979
227	6-Phosphofructo-2-kinase inhibitor	11	0.9935
228	6-Pyruvoyltetrahydropterin synthase inhibitor	4	0.9873
229	8-Amino-7-oxononanoate synthase inhibitor	15	0.9759
230	8-oxodGTPase stimulant	12	0.9998
231	ABCA1 expression enhancer	211	0.9777
232	Abl kinase inhibitor	604	0.9708
233	Abortion inducer	38	0.9493
234	Acaricide	42	0.9447
235	Acetate kinase inhibitor	11	0.9080
236	Acetate-CoA ligase inhibitor	23	0.9869
237	Acetoacetate decarboxylase inhibitor	8	0.9924
238	Acetoacetyl-CoA reductase inhibitor	10	0.9980
239	Acetoin dehydrogenase inhibitor	15	0.9858
240	Acetolactate decarboxylase inhibitor	15	0.9828
241	Acetolactate synthase inhibitor	20	0.9840
242	Acetylcholine agonist	2053	0.9739
243	Acetylcholine antagonist	3940	0.9725
244	Acetylcholine M1 receptor agonist	1014	0.9922
245	Acetylcholine M1 receptor antagonist	1263	0.9878
246	Acetylcholine M2 receptor agonist	39	0.9710
247	Acetylcholine M2 receptor antagonist	1374	0.9887
248	Acetylcholine M3 receptor agonist	16	0.9963
249	Acetylcholine M3 receptor antagonist	1397	0.9863
250	Acetylcholine M4 receptor agonist	57	0.9949
251	Acetylcholine M4 receptor antagonist	706	0.9885
252	Acetylcholine M5 receptor antagonist	591	0.9895
253	Acetylcholine muscarinic agonist	1216	0.9883
254	Acetylcholine muscarinic antagonist	3051	0.9786
255	Acetylcholine neuromuscular blocking agent	18	0.8275
256	Acetylcholine nicotinic agonist	802	0.9784
257	Acetylcholine nicotinic antagonist	947	0.9789
258	Acetylcholine release stimulant	146	0.9625
259	Acetylcholinesterase stimulant	6	0.9999
260	Acetyl-CoA C-acyltransferase inhibitor	10	0.9641
261	Acetyl-CoA carboxylase 1 inhibitor	96	0.9920
262	Acetyl-CoA carboxylase 2 inhibitor	260	1.0000
263	Acetyl-CoA carboxylase inhibitor	279	0.9918
264	Acetyl-CoA transferase 1 inhibitor	602	0.9897
265	Acetyl-CoA transferase 2 inhibitor	226	0.9797
266	Acetyl-CoA transferase inhibitor	1569	0.9888
267	Acetylenecarboxylate hydratase inhibitor	3	0.9889
268	Acetylesterase inhibitor	6	0.8663
269	Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase inhibitor	6	0.8268
270	Acetylornithine deacetylase inhibitor	4	0.9849
271	Acetylserotonin O-methyltransferase inhibitor	11	0.9115
272	Acetylspermidine deacetylase inhibitor	16	0.9512
273	Acid phosphatase 1 inhibitor	5	1.0000
274	Acid phosphatase inhibitor	43	0.9551
275	Acidifying agent gastric	6	0.9981
276	Acidifying agent non gastric	7	0.9552
277	Acidosis	130	0.8121
278	Acidosis, lactic	9	0.8839
279	Acidosis, metabolic	45	0.8461
280	Acid-sensing ion channel blocker	6	0.8824
281	ACK1 kinase inhibitor	9	0.9333
282	Acneiform eruption	3	0.9468
283	Aconitate decarboxylase inhibitor	4	0.9960
284	Aconitate hydratase inhibitor	22	0.9919
285	Acrocylindropepsin inhibitor	3	0.8770
286	Acrosin inhibitor	20	0.9651
287	Actin depolymerization stimulant	8	0.9984
288	Actin polymerization inhibitor	5	1.0000
289	Activin receptor-like kinase 4 inhibitor	23	0.9998
290	Acute neurologic disorders treatment	1183	0.8103
291	Acylaminoacyl-peptidase inhibitor	25	0.9633
292	Acylcarnitine hydrolase inhibitor	3	0.9187
293	Acyl-CoA dehydrogenase (NADP+) inhibitor	19	0.9895
294	Acyl-CoA dehydrogenase inhibitor	15	0.9935
295	Acyl-CoA hydrolase inhibitor	44	0.9787
296	Acyl-CoA oxidase inhibitor	11	0.9143
297	Acylglycerone-phosphate reductase inhibitor	6	0.9857
298	Acyl-lysine deacylase inhibitor	3	0.9942
299	Acyloxyacyl hydrolase inhibitor	15	0.9862
300	Acylphosphatase inhibitor	13	0.9791
301	ADAM inhibitor	54	0.9970
302	ADAM10 endopeptidase inhibitor	125	0.9866
303	Adamalysin inhibitor	8	0.9967
304	Adenine deaminase inhibitor	10	0.9877
305	Adenine nucleotide translocase inhibitor	23	0.9632
306	Adenine nucleotide translocator 1 inhibitor	3	1.0000
307	Adenine phosphoribosyltransferase inhibitor	23	0.9948
308	Adenomatous polyposis treatment	10	0.9408
309	Adenosine A1 receptor agonist	273	0.9990
310	Adenosine A1 receptor agonist enhancer	10	1.0000
311	Adenosine A1 receptor antagonist	2623	0.9888
312	Adenosine A2 receptor agonist	239	0.9989
313	Adenosine A2 receptor antagonist	2819	0.9896
314	Adenosine A2a receptor agonist	216	0.9991
315	Adenosine A2a receptor antagonist	2091	0.9897
316	Adenosine A2b receptor agonist	17	0.9989
317	Adenosine A2b receptor antagonist	852	0.9931
318	Adenosine A3 receptor agonist	88	0.9980
319	Adenosine A3 receptor antagonist	1365	0.9803
320	Adenosine deaminase inhibitor	165	0.9838
321	Adenosine kinase inhibitor	334	0.9959
322	Adenosine receptor agonist	614	0.9947
323	Adenosine receptor antagonist	4310	0.9828
324	Adenosine regulator	3	0.9014
325	Adenosine uptake inhibitor	55	0.9995
326	Adenosylhomocysteine nucleosidase inhibitor	57	0.9999
327	Adenosylmethionine cyclotransferase inhibitor	12	0.9996
328	Adenosylmethionine-8-amino-7-oxononanoate transaminase inhibitor	12	0.9865
329	Adenylate cyclase I inhibitor	54	0.9969
330	Adenylate cyclase I stimulant	43	1.0000
331	Adenylate cyclase inhibitor	174	0.9497
332	Adenylate cyclase stimulant	89	0.9372
333	Adenylate cyclase V inhibitor	36	0.9598
334	Adenylate kinase inhibitor	23	0.9355
335	Adenylosuccinate lyase inhibitor	29	0.9961
336	Adenylosuccinate synthase inhibitor	60	0.9916
337	Adenylyl-sulfate kinase inhibitor	20	0.9723
338	Adenylyl-sulfate reductase inhibitor	5	0.8988
339	Adenylylsulphatase inhibitor	17	0.9808
340	ADP-ribose diphosphatase inhibitor	7	0.9978
341	ADP-ribosylarginine hydrolase inhibitor	6	0.9241
342	ADP-thymidine kinase inhibitor	5	0.9523
343	Adrenal cortex hypoplasia	3	0.9249
344	Adrenaline agonist	2055	0.9787
345	Adrenaline antagonist	6430	0.9718
346	Adrenaline release stimulant	8	0.9338
347	Adrenaline uptake inhibitor	2366	0.9878
348	Adrenergic	4509	0.9763
349	Adrenergic, ophthalmic	9	0.9917
350	Aerobactin synthase inhibitor	3	0.9912
351	Agaritine gamma-glutamyltransferase inhibitor	11	0.9903
352	Age-related macular degeneration treatment	51	0.8810
353	Aggrecanase 1 inhibitor	48	0.9768
354	Aggrecanase 2 inhibitor	117	0.9941
355	Aggrecanase inhibitor	310	0.9948
356	Agmatinase inhibitor	7	0.9243
357	Agranulocytosis	408	0.8408
358	AgrC-1 protein inhibitor	4	1.0000
359	AgrC-2 protein inhibitor	4	1.0000
360	AICAR transformylase inhibitor	39	0.9618
361	Akathisia	84	0.8463
362	Alanine carboxypeptidase inhibitor	10	0.9941
363	Alanine dehydrogenase inhibitor	27	0.9892
364	Alanine racemase inhibitor	12	0.9843
365	Alanine transaminase inhibitor	18	0.9862
366	Alanine-tRNA ligase inhibitor	6	0.9698
367	Albendazole monooxygenase inhibitor	3	0.9698
368	Alcohol dehydrogenase (acceptor) inhibitor	11	0.8721
369	Alcohol dehydrogenase (NADP+) inhibitor	45	0.9587
370	Alcohol dehydrogenase [NAD(P)+] inhibitor	16	0.9279
371	Alcohol dehydrogenase alpha inhibitor	12	1.0000
372	Alcohol dehydrogenase beta 1 inhibitor	7	1.0000
373	Alcohol dehydrogenase beta inhibitor	7	1.0000
374	Alcohol dehydrogenase gamma 2 inhibitor	6	0.9999
375	Alcohol dehydrogenase gamma inhibitor	6	0.9999
376	Alcohol dehydrogenase I inhibitor	14	1.0000
377	Alcohol dehydrogenase inhibitor	119	0.9569
378	Alcohol dehydrogenase substrate	71	0.9547
379	Alcohol O-acetyltransferase inhibitor	9	0.9079
380	Alcohol oxidase inhibitor	17	0.9888
381	Aldehyde dehydrogenase (NAD+) inhibitor	38	0.9602
382	Aldehyde dehydrogenase (NADP+) inhibitor	17	0.9668
383	Aldehyde dehydrogenase (pyrroloquinoline-quinone) inhibitor	7	0.8766
384	Aldehyde dehydrogenase [NAD(P)+] inhibitor	5	0.9924
385	Aldehyde dehydrogenase 1 substrate	8	0.9989
386	Aldehyde dehydrogenase 1A2 inhibitor	30	0.9946
387	Aldehyde dehydrogenase 2 substrate	6	0.8550
388	Aldehyde dehydrogenase 3 substrate	5	0.9987
389	Aldehyde dehydrogenase inhibitor	114	0.9600
390	Aldehyde dehydrogenase substrate	55	0.9595
391	Aldehyde ferredoxin oxidoreductase inhibitor	5	0.9886
392	Aldehyde oxidase inhibitor	27	0.8903
393	Aldehyde oxidase substrate	51	0.9422
394	Aldose 1-epimerase inhibitor	31	0.9932
395	Aldose reductase 2 inhibitor	88	0.9956
396	Aldose reductase inhibitor	803	0.9861
397	Aldose reductase substrate	11	0.9636
398	Aldosterone antagonist	58	0.8716
399	ALK inhibitor	121	0.9636
400	Alkaline phosphatase inhibitor	336	0.9569
401	Alkanal monooxygenase (FMN-linked) inhibitor	27	0.9583
402	Alkane 1-monooxygenase inhibitor	4	0.9508
403	Alkene monooxygenase inhibitor	3	0.9908
404	Alkenylglycerophosphocholine hydrolase inhibitor	5	0.9109
405	Alkenylglycerophosphoethanolamine hydrolase inhibitor	6	0.9306
406	Alkylacetylglycerophosphatase inhibitor	4	0.8816
407	Alkylator	562	0.9471
408	Alkylglycerone-phosphate synthase inhibitor	6	0.9804
409	Alkylglycerophosphoethanolamine phosphodiesterase inhibitor	5	0.9726
410	Allantoate deiminase inhibitor	3	0.9931
411	Allantoicase inhibitor	9	0.9897
412	Allantoin racemase inhibitor	4	0.9903
413	Allantoinase inhibitor	4	0.9927
414	Allergic contact dermatitis	93	0.8449
415	Allergic dermatitis	73	0.8531
416	Allergic rhinitis treatment	409	0.9643
417	Allophanate hydrolase inhibitor	5	0.9864
418	All-trans-retinyl-palmitate hydrolase inhibitor	4	0.9450
419	Allyl-alcohol dehydrogenase inhibitor	6	0.9827
420	Alopecia treatment	6	0.8647
421	Alpha 1 adrenoreceptor agonist	78	0.9922
422	Alpha 1 adrenoreceptor antagonist	3876	0.9781
423	Alpha 1a adrenoreceptor agonist	48	0.9997
424	Alpha 1a adrenoreceptor antagonist	3142	0.9824
425	Alpha 1b adrenoreceptor antagonist	1331	0.9832
426	Alpha 1d adrenoreceptor antagonist	1512	0.9854
427	Alpha 1L adrenoreceptor agonist	3	0.9933
428	Alpha 1L adrenoreceptor antagonist	11	0.9722
429	Alpha 2 adrenoreceptor agonist	337	0.9871
430	Alpha 2 adrenoreceptor antagonist	1608	0.9802
431	Alpha 2a adrenoreceptor antagonist	629	0.9809
432	Alpha 2b adrenoreceptor agonist	45	0.9992
433	Alpha 2b adrenoreceptor antagonist	420	0.9749
434	Alpha 2c adrenoreceptor agonist	45	0.9996
435	Alpha 2c adrenoreceptor antagonist	497	0.9778
436	Alpha 2d adrenoreceptor agonist	44	0.9984
437	Alpha 2d adrenoreceptor antagonist	94	0.9881
438	Alpha 3 adrenoreceptor agonist	5	0.9935
439	Alpha adrenoreceptor agonist	496	0.9798
440	Alpha adrenoreceptor antagonist	5126	0.9709
441	Alpha galactosidase inhibitor	16	0.9996
442	Alpha glucosidase I inhibitor	5	0.9999
443	Alpha glucosidase II inhibitor	8	1.0000
444	Alpha glucosidase inhibitor	115	0.9797
445	Alpha,alpha-phosphotrehalase inhibitor	5	0.9931
446	Alpha,alpha-trehalase inhibitor	20	0.9858
447	Alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitor	11	0.9946
448	Alpha,alpha-trehalose phosphorylase inhibitor	4	0.9986
449	Alpha,alpha-trehalose-phosphate synthase (UDP-forming) inhibitor	14	0.9690
450	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase inhibitor	11	0.9985
451	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase inhibitor	3	0.9964
452	Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase inhibitor	4	0.9599
453	Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase inhibitor	5	0.9913
454	Alpha-amino-acid esterase inhibitor	4	0.9991
455	Alpha-amylase inhibitor	28	0.9486
456	Alpha-glucuronidase inhibitor	4	0.9788
457	Alpha-L-fucosidase inhibitor	44	0.9906
458	Alpha-L-rhamnosidase inhibitor	11	0.9937
459	Alpha-mannosidase inhibitor	59	0.9852
460	Alpha-Methylacyl-CoA racemase inhibitor	8	0.9811
461	Alpha-N-acetylgalactosaminidase inhibitor	3	0.9947
462	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase inhibitor	17	0.9957
463	Alpha-N-acetylglucosaminidase inhibitor	4	0.9797
464	Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase inhibitor	15	0.9973
465	Alpha-N-arabinofuranosidase inhibitor	9	0.9832
466	Alpha-pinene-oxide decyclase inhibitor	8	0.9879
467	Alternansucrase inhibitor	4	0.9976
468	Altronate dehydratase inhibitor	7	0.9989
469	Alzheimer's disease treatment	2493	0.8918
470	Amidase inhibitor	124	0.9737
471	Amidophosphoribosyltransferase inhibitor	25	0.9973
472	Amiloride-sensitive cation channel 3 blocker	7	1.0000
473	Amine dehydrogenase inhibitor	10	0.8736
474	Amino acid-polyamine-organocation (APC) transporter antagonist	82	0.9998
475	Amino-acid N-acetyltransferase inhibitor	25	0.9932
476	Amino-acid racemase inhibitor	6	0.9961
477	Aminoacylase inhibitor	19	0.9827
478	Aminoacyl-tRNA hydrolase inhibitor	5	0.9944
479	Aminoacyl-tRNA synthetase inhibitor	321	0.9748
480	Aminobutyraldehyde dehydrogenase inhibitor	3	0.8691
481	Aminocarboxymuconate-semialdehyde decarboxylase inhibitor	6	0.9885
482	Aminoglycoside N6'-acetyltransferase inhibitor	15	0.9997
483	Aminolevulinate transaminase inhibitor	26	0.9909
484	Aminomuconate-semialdehyde dehydrogenase inhibitor	4	0.9795
485	Aminopeptidase A inhibitor	55	0.9991
486	Aminopeptidase B inhibitor	45	0.9395
487	Aminopeptidase I inhibitor	26	0.9838
488	Aminopeptidase microsomal inhibitor	209	0.9787
489	Aminopeptidase N inhibitor	183	0.9820
490	Aminopeptidase P inhibitor	9	1.0000
491	Aminopeptidase Y inhibitor	8	0.9778
492	AMP deaminase 2 inhibitor	69	1.0000
493	AMP deaminase 3 inhibitor	21	0.9978
494	AMP deaminase inhibitor	103	0.9863
495	AMP nucleosidase inhibitor	15	0.9952
496	AMPA 1 receptor antagonist	681	0.9954
497	AMPA 2 receptor antagonist	452	0.9922
498	AMPA 3 receptor antagonist	437	0.9925
499	AMPA 4 receptor antagonist	222	0.9888
500	AMPA 5 receptor antagonist	4	1.0000
501	AMPA receptor agonist	72	0.9939
502	AMPA receptor antagonist	1317	0.9905
503	Amylin agonist	10	1.0000
504	Amylo-alpha-1,6-glucosidase inhibitor	26	0.9930
505	Amyloid beta aggregation inhibitor	39	0.9747
506	Amyloid beta precursor protein antagonist	295	0.9471
507	Amylosucrase inhibitor	5	0.9990
508	Amyotrophic lateral sclerosis treatment	180	0.9038
509	Anabolic	158	0.9603
510	Analeptic	234	0.8912
511	Analgesic	8418	0.8650
512	Analgesic stimulant	22	0.8677
513	Analgesic, non-opioid	6210	0.8827
514	Anaphylatoxin receptor antagonist	5	0.8968
515	Androgen agonist	219	0.9854
516	Androgen antagonist	1280	0.9821
517	Andropause treatment	85	0.9732
518	Androst-4-ene-3,17-dione monooxygenase inhibitor	9	0.9931
519	Anemia	228	0.8481
520	Anemia, sideroblastic	4	0.9738
521	Anesthetic	707	0.9413
522	Anesthetic general	151	0.9117
523	Anesthetic inhalation	20	0.9878
524	Anesthetic local	463	0.9611
525	Angiogenesis inhibitor	4489	0.9084
526	Angiogenesis stimulant	23	0.8636
527	Angiotensin agonist	12	0.9909
528	Angiotensin antagonist	3433	0.9894
529	Angiotensin AT1 receptor antagonist	3018	0.9897
530	Angiotensin AT1A receptor antagonist	973	0.9977
531	Angiotensin AT2 receptor agonist	7	0.9874
532	Angiotensin AT2 receptor antagonist	1039	0.9971
533	Angiotensin II receptor agonist	9	0.9259
534	Angiotensin II receptor antagonist	3407	0.9900
535	Angiotensin-converting enzyme inhibitor	694	0.9840
536	Anhydrotetracycline monooxygenase inhibitor	4	0.9959
537	Anorexiant	363	0.8281
538	Anthranilate 3-monooxygenase (deaminating) inhibitor	11	0.9584
539	Anthranilate phosphoribosyltransferase inhibitor	5	0.9966
540	Anthranilate synthase inhibitor	23	0.9848
541	Anthranilate-CoA ligase inhibitor	4	0.9820
542	Anthrax lethal factor inhibitor	61	0.9347
543	Antiacne	1202	0.9697
544	Antiacromegalic	71	0.9763
545	Antiadrenergic	6501	0.9702
546	Antialcoholic	121	0.9102
547	Antiallergic	6195	0.8818
548	Antiamyloidogenic	269	0.8962
549	Antianemic	182	0.9477
550	Antianginal	850	0.8299
551	Antianorexic	63	0.9316
552	Antiarrhythmic	2201	0.9347
553	Antiarthritic	9453	0.8648
554	Antiasthmatic	7609	0.8877
555	Antibacterial	6950	0.9192
556	Antibacterial, ophthalmic	11	0.9146
557	Antibiotic	3481	0.9682
558	Antibiotic Aminoglycoside-like	48	0.9685
559	Antibiotic Anthracycline-like	7	0.9622
560	Antibiotic beta Lactam-like	768	0.9951
561	Antibiotic Carbacephem-like	22	0.9998
562	Antibiotic Carbapenem-like	153	0.9987
563	Antibiotic Cephalosporin-like	348	0.9996
564	Antibiotic Glycopeptide-like	32	0.9809
565	Antibiotic Isocephem-like	7	1.0000
566	Antibiotic Macrolide-like	584	0.9982
567	Antibiotic Naphthyridine-like	30	0.9997
568	Antibiotic Oxacephem-like	12	0.9992
569	Antibiotic Oxazolidinone-like	90	0.9900
570	Antibiotic Penem-like	41	0.9999
571	Antibiotic Penicillin-like	50	0.9998
572	Antibiotic Quinolone-like	305	0.9918
573	Antibiotic Rifamycin-like	64	1.0000
574	Antibiotic Tetracycline-like	12	0.9807
575	Antibiotic Tribactam-like	17	1.0000
576	Antibiotic Trimethoprim-like	10	0.9998
577	Anticarcinogenic	368	0.9080
578	Anticataract	63	0.9497
579	Anticholelithogenic	41	0.9784
580	Anticoagulant	2397	0.9489
581	Anticonvulsant	1466	0.8832
582	Antidepressant	8006	0.9193
583	Antidepressant, Imipramin-like	87	0.9574
584	Antidiabetic	11530	0.8929
585	Antidiabetic (type 1)	102	0.9315
586	Antidiabetic (type 2)	2835	0.9415
587	Antidiabetic symptomatic	713	0.8985
588	Antidiarrheal	256	0.9030
589	Antidiuretic hormone agonist	151	0.9975
590	Antidiuretic hormone antagonist	1247	0.9947
591	Antidote	122	0.9318
592	Antidote, heavy metal	48	0.9819
593	Antidote, organophosphates	4	1.0000
594	Antidyskinetic	22	0.8011
595	Antieczematic	8	0.8230
596	Antieczematic atopic	333	0.8924
597	Antiemetic	1023	0.9583
598	Antiemphysemic	209	0.9475
599	Antiepileptic	2456	0.9294
600	Antifibrinolytic	17	0.8457
601	Antifungal	2087	0.9119
602	Antifungal (Pneumocystis)	9	0.9701
603	Antifungal enhancer	20	0.9556
604	Antiglaucomic	1378	0.9431
605	Anti-Helicobacter pylori	143	0.9031
606	Antihelmintic	461	0.9298
607	Antihelmintic (Fasciola)	5	0.9673
608	Antihelmintic (Nematodes)	56	0.8950
609	Antihematotoxic	31	0.8984
610	Antihemorrhagic	16	0.9462
611	Antihistaminic	2969	0.9525
612	Antihyperaldosteronism	81	0.9986
613	Antihyperammonemic	3	0.9980
614	Antihypercholesterolemic	248	0.9262
615	Antihyperlipoproteinemic	83	0.9553
616	Antihypermotility	77	0.9533
617	Antihypertensive	7874	0.9007
618	Antihypertriglyceridemic	137	0.9709
619	Antihypotensive	38	0.9002
620	Antihypoxic	38	0.8663
621	Antiinfective	178	0.8682
622	Antiinfertility, female	67	0.9257
623	Antiinflammatory	5983	0.8384
624	Antiinflammatory steroid	3	0.9999
625	Antiinflammatory, intestinal	9	0.9114
626	Antiinflammatory, ophthalmic	51	0.8549
627	Antiischemic	2210	0.8978
628	Antiischemic, cerebral	439	0.7724
629	Antileprosy	56	0.9390
630	Antileukemic	4964	0.9392
631	Antimetabolite	732	0.9877
632	Antimetastatic	20	0.8854
633	Antimigraine	1980	0.9437
634	Antimitotic	1925	0.9426
635	Antimitotic, Podophyllotoxin-like	3	0.9996
636	Antimutagenic	34	0.9587
637	Antimycobacterial	726	0.8861
638	Antimycoplasmal	37	0.9353
639	Antimyopathies	6	0.8705
640	Antinaupathic	17	0.9496
641	Antineoplastic	49620	0.8600
642	Antineoplastic (bladder cancer)	330	0.9195
643	Antineoplastic (bone cancer)	68	0.8915
644	Antineoplastic (brain cancer)	512	0.8931
645	Antineoplastic (breast cancer)	5569	0.9292
646	Antineoplastic (carcinoma)	1904	0.9626
647	Antineoplastic (cervical cancer)	2035	0.9598
648	Antineoplastic (colon cancer)	5457	0.9519
649	Antineoplastic (colorectal cancer)	5654	0.9465
650	Antineoplastic (endocrine cancer)	167	0.9092
651	Antineoplastic (gastric cancer)	541	0.9393
652	Antineoplastic (glioblastoma multiforme)	347	0.9156
653	Antineoplastic (glioma)	497	0.9348
654	Antineoplastic (insulinoma)	44	0.9999
655	Antineoplastic (liver cancer)	363	0.9181
656	Antineoplastic (lung cancer)	2975	0.9384
657	Antineoplastic (lymphocytic leukemia)	2803	0.9570
658	Antineoplastic (lymphoma)	979	0.9355
659	Antineoplastic (melanoma)	1397	0.9377
660	Antineoplastic (multiple myeloma)	199	0.8722
661	Antineoplastic (non-Hodgkin's lymphoma)	73	0.8131
662	Antineoplastic (non-small cell lung cancer)	872	0.9146
663	Antineoplastic (ovarian cancer)	2006	0.9504
664	Antineoplastic (pancreatic cancer)	312	0.8817
665	Antineoplastic (renal cancer)	466	0.9247
666	Antineoplastic (sarcoma)	320	0.9122
667	Antineoplastic (small cell lung cancer)	186	0.8764
668	Antineoplastic (solid tumors)	709	0.8687
669	Antineoplastic (squamous cell carcinoma)	1226	0.9673
670	Antineoplastic (thyroid cancer)	59	0.9074
671	Antineoplastic (uterine cancer)	139	0.9374
672	Antineoplastic alkaloid	23	0.9106
673	Antineoplastic antibiotic	1599	0.9783
674	Antineoplastic antimetabolite	166	0.9507
675	Antineoplastic enhancer	774	0.9081
676	Antineoplastic, alkylator	118	0.9671
677	Antinephritic	83	0.8514
678	Antineurogenic pain	561	0.8844
679	Antineurotic	47	0.8063
680	Antinociceptive	41	0.8573
681	Antiobesity	7769	0.9117
682	Antiosteoporotic	2666	0.9266
683	Antioxidant	843	0.9388
684	Antiparasitic	605	0.9272
685	Antiparkinsonian	2768	0.8938
686	Antiparkinsonian, rigidity relieving	37	0.9269
687	Antiparkinsonian, tremor relieving	114	0.9430
688	Antiperistaltic	10	0.9467
689	Antiprotozoal	2191	0.9152
690	Antiprotozoal (Amoeba)	88	0.8685
691	Antiprotozoal (Babesia)	5	0.9739
692	Antiprotozoal (Coccidial)	98	0.9027
693	Antiprotozoal (Histomonas)	7	0.9963
694	Antiprotozoal (Leishmania)	151	0.8793
695	Antiprotozoal (Plasmodium)	1322	0.9382
696	Antiprotozoal (Toxoplasma)	21	0.9204
697	Antiprotozoal (Trichomonas)	89	0.9183
698	Antiprotozoal (Trypanosoma)	225	0.8786
699	Antiprotozoal activity enhancer	5	1.0000
700	Antipruritic	268	0.8756
701	Antipruritic, allergic	146	0.8504
702	Antipruritic, non-allergic	68	0.9386
703	Antipsoriatic	1771	0.8972
704	Antipsychotic	6680	0.9291
705	Antipyretic	410	0.9186
706	Antirickettsial	18	0.9426
707	Antischistosomal	39	0.9434
708	Antiseborrheic	10	0.9069
709	Antisecretoric	192	0.9073
710	Antiseptic	170	0.9572
711	Antismoking	189	0.9738
712	Antispirochetal	35	0.9629
713	Antithrombocytopenic	144	0.9803
714	Antithrombotic	557	0.8755
715	Antithyroid	40	0.9460
716	Antitoxic	145	0.9049
717	Antitreponemal	8	0.9194
718	Antituberculosic	434	0.8837
719	Antitussive	247	0.9355
720	Antitussive, narcotic	35	0.9677
721	Antiulcerative	893	0.8868
722	Antiuremic	39	0.9324
723	Antiviral	11347	0.9180
724	Antiviral (Adenovirus)	23	0.8787
725	Antiviral (CMV)	15	0.8695
726	Antiviral (Hepatitis B)	53	0.9037
727	Antiviral (Hepatitis C)	1472	0.9647
728	Antiviral (Hepatitis)	1753	0.9559
729	Antiviral (Herpes)	142	0.8940
730	Antiviral (Herpesvirus 3, Human)	7	1.0000
731	Antiviral (HIV)	7050	0.9475
732	Antiviral (Influenza A)	31	0.8733
733	Antiviral (Influenza)	150	0.8826
734	Antiviral (Parainfluenza)	5	0.9999
735	Antiviral (Picornavirus)	31	0.8105
736	Antiviral (Poxvirus)	41	0.9041
737	Antiviral (Rhinovirus)	13	0.8066
738	Antiviral (Trachoma)	12	0.9872
739	Anxiolytic	8121	0.9103
740	Apical sodium codependent bile acid transporter inhibitor	16	1.0000
741	Apnea	24	0.8961
742	APOA1 expression enhancer	17	0.8257
743	Apolipoprotein A inhibitor	71	1.0000
744	Apolipoprotein B inhibitor	225	0.9955
745	Apolipoprotein B-100 inhibitor	50	0.9985
746	Apoptosis agonist	1299	0.8655
747	Apoptosis antagonist	248	0.9008
748	Apyrase inhibitor	17	0.8180
749	AR expression inhibitor	31	0.8773
750	Arabinogalactan endo-1,4-beta-galactosidase inhibitor	4	0.9982
751	Arabinose isomerase inhibitor	7	0.9934
752	Arabinose-5-phosphate isomerase inhibitor	4	0.9997
753	Arachidonate-CoA ligase inhibitor	7	0.9987
754	Arachidonic acid antagonist	93	0.9438
755	Aralkylamine dehydrogenase inhibitor	6	0.9992
756	Aralkylamine N-acetyltransferase inhibitor	16	0.9885
757	Arginase inhibitor	34	0.9930
758	Arginine 2-monooxygenase inhibitor	4	0.8953
759	Arginine decarboxylase inhibitor	38	0.9845
760	Arginine deiminase inhibitor	22	0.9473
761	Arginine kinase inhibitor	12	0.9951
762	Arginine N-succinyltransferase inhibitor	3	0.9997
763	Arginine racemase inhibitor	3	0.9994
764	Arginine-tRNA ligase inhibitor	17	0.9942
765	Argininosuccinate lyase inhibitor	10	0.9937
766	Argininosuccinate synthase inhibitor	21	0.9886
767	Arginyltransferase inhibitor	6	0.9938
768	Aromatase inhibitor	1202	0.9909
769	Aromatic-amino-acid transaminase inhibitor	14	0.9887
770	Aromatic-hydroxylamine O-acetyltransferase inhibitor	7	0.8507
771	Aryl hydrocarbon receptor agonist	12	0.9209
772	Aryl hydrocarbon receptor antagonist	57	0.9776
773	Aryl sulfotransferase inhibitor	30	0.9516
774	Arylacetonitrilase inhibitor	11	0.9642
775	Aryl-acylamidase inhibitor	35	0.9218
776	Aryl-alcohol dehydrogenase (NADP+) inhibitor	7	0.9854
777	Aryl-alcohol dehydrogenase inhibitor	10	0.9854
778	Aryl-aldehyde dehydrogenase (NADP+) inhibitor	6	0.9908
779	Arylalkyl acylamidase inhibitor	6	0.9881
780	Arylamine N-acetyltransferase inhibitor	33	0.9439
781	Arylamine N-Acetyltransferase substrate	103	0.9854
782	Aryldialkylphosphatase inhibitor	5	0.9838
783	Arylesterase inhibitor	9	0.9351
784	Arylformamidase inhibitor	28	0.9840
785	Arylmalonate decarboxylase inhibitor	3	0.9727
786	Arylsulfatase inhibitor	22	0.9741
787	Arylsulfate sulfotransferase inhibitor	7	0.9093
788	Asparaginase inhibitor	19	0.9648
789	Asparagine synthase (glutamine-hydrolysing) inhibitor	81	0.9935
790	Asparagine-oxo-acid transaminase inhibitor	17	0.9947
791	Asparagine-tRNA ligase inhibitor	6	0.9901
792	Asparaginyl endopeptidase inhibitor	54	0.9924
793	Aspartate 1-decarboxylase inhibitor	7	0.9958
794	Aspartate 4-decarboxylase inhibitor	19	0.9832
795	Aspartate ammonia-lyase inhibitor	26	0.9946
796	Aspartate carbamoyltransferase inhibitor	26	0.9858
797	Aspartate kinase inhibitor	24	0.9516
798	Aspartate N-acetyltransferase inhibitor	3	0.9999
799	Aspartate racemase inhibitor	4	0.9942
800	Aspartate transaminase inhibitor	21	0.9848
801	Aspartate-ammonia ligase (ADP-forming) inhibitor	4	0.9937
802	Aspartate-ammonia ligase inhibitor	3	0.9764
803	Aspartate-phenylpyruvate transaminase inhibitor	4	0.8708
804	Aspartate-semialdehyde dehydrogenase inhibitor	13	0.9928
805	Aspartate-tRNA ligase inhibitor	6	0.9855
806	Aspartoacylase inhibitor	4	0.9852
807	Aspartyl aminopeptidase inhibitor	8	0.9886
808	Aspartyl protease inhibitor	3	1.0000
809	Aspartyltransferase inhibitor	4	0.8491
810	Aspergillopepsin I inhibitor	8	0.9302
811	Aspergillopepsin II inhibitor	4	0.9479
812	Aspergillus nuclease S1 inhibitor	8	0.9495
813	Aspulvinone dimethylallyltransferase inhibitor	3	0.8428
814	Assemblin inhibitor	7	0.9949
815	Astacin inhibitor	19	0.9851
816	Asthma	202	0.7902
817	Astringent	11	0.9907
818	Ataxia	433	0.8297
819	Atherosclerosis treatment	3679	0.8892
820	ATM kinase inhibitor	74	0.9833
821	ATP adenylyltransferase inhibitor	7	0.9853
822	ATP citrate lysase inhibitor	47	0.9963
823	ATP citrate synthase inhibitor	20	0.9966
824	ATP deaminase inhibitor	5	0.9970
825	ATP diphosphatase inhibitor	4	0.9954
826	ATP phosphoribosyltransferase inhibitor	16	0.9237
827	ATPase (Mitochondrial F1F0) inhibitor	17	0.9998
828	ATPase (Vacuolar H+) inhibitor	73	0.9929
829	ATPase inhibitor	150	0.9327
830	ATPase stimulant	18	0.8749
831	ATP-binding cassette A1 stimulant	3	0.9529
832	ATP-dependent RNA helicase inhibitor	10	1.0000
833	Atrolysin A inhibitor	11	0.9515
834	Atrolysin C inhibitor	10	0.9811
835	Attention deficit/hyperactivity disorder treatment	666	0.9741
836	Aureolysin inhibitor	4	0.9838
837	Aurora kinase inhibitor	999	0.9818
838	Aurora-A kinase inhibitor	600	0.9823
839	Aurora-B kinase inhibitor	504	0.9851
840	Aurora-C kinase inhibitor	46	0.9655
841	Autoimmune disorders treatment	3972	0.8791
842	Autophagy inducer	3	0.9338
843	Autotaxin inhibitor	50	0.9734
844	AXL receptor tyrosine kinase inhibitor	40	0.9419
845	Azobenzene reductase inhibitor	5	0.9855
846	Bacillus subtilis ribonuclease inhibitor	6	0.9963
847	Bacterial efflux pump inhibitor	16	0.9125
848	Bacterial leucyl aminopeptidase inhibitor	29	0.9931
849	Baculoviral IAP repeat-containing protein 4 inhibitor	118	0.9914
850	Baculoviral IAP repeat-containing protein inhibitor	162	0.9915
851	Bcl2 antagonist	134	0.9300
852	Bcl-xL inhibitor	120	0.9815
853	Bcr-Abl kinase inhibitor	91	0.9502
854	Behavioral disturbance	1535	0.8342
855	Benzaldehyde dehydrogenase (NAD+) inhibitor	8	0.9941
856	Benzaldehyde dehydrogenase (NADP+) inhibitor	3	0.9776
857	Benzoate 4-monooxygenase inhibitor	19	0.9384
858	Benzoate-CoA ligase inhibitor	6	0.8950
859	Benzodiazepine antagonist	455	0.9885
860	Benzodiazepine inverse agonist	59	0.9912
861	Benzodiazepine receptor peripheral-type antagonist	425	0.9967
862	Benzoin aldolase inhibitor	3	0.9997
863	Benzoylformate decarboxylase inhibitor	9	0.8942
864	Beta 1 adrenoreceptor agonist	49	0.9764
865	Beta 1 adrenoreceptor antagonist	677	0.9888
866	Beta 2 adrenoreceptor agonist	683	0.9948
867	Beta 2 adrenoreceptor antagonist	670	0.9897
868	Beta 3 adrenoreceptor agonist	772	0.9969
869	Beta 3 adrenoreceptor antagonist	156	0.9876
870	Beta adrenoreceptor agonist	1554	0.9884
871	Beta adrenoreceptor antagonist	1418	0.9818
872	Beta amyloid protein antagonist	122	0.9730
873	Beta galactosidase inhibitor	81	0.9935
874	Beta glucosidase inhibitor	22	0.9982
875	Beta glucuronidase inhibitor	15	0.8693
876	Beta lactamase II inhibitor	18	1.0000
877	Beta lactamase Imi-1 inhibitor	5	0.9992
878	Beta lactamase inhibitor	437	0.9626
879	Beta lactamase TEM-1 inhibitor	42	0.9994
880	Beta tubulin antagonist	478	0.9907
881	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase inhibitor	13	0.9933
882	Beta-adrenergic receptor kinase inhibitor	22	0.8262
883	Beta-alanine-pyruvate transaminase inhibitor	3	0.9893
884	Beta-amylase inhibitor	9	0.9940
885	Beta-carotene 15,15'-monooxygenase inhibitor	17	0.9417
886	Beta-cyclopiazonate dehydrogenase inhibitor	7	0.9829
887	Beta-D-fucosidase inhibitor	20	0.9895
888	Beta-fructofuranosidase inhibitor	43	0.9914
889	Beta-galactoside alpha-2,3-sialyltransferase inhibitor	10	0.9985
890	Beta-glucosidase inhibitor	59	0.9887
891	Betaine-aldehyde dehydrogenase inhibitor	18	0.9926
892	Betaine-homocysteine S-methyltransferase inhibitor	9	0.9982
893	Beta-Lysine 5,6-aminomutase inhibitor	4	0.9975
894	Beta-mannosidase inhibitor	10	0.9863
895	Beta-N-acetylgalactosaminidase inhibitor	3	0.9845
896	Beta-N-acetylhexosaminidase inhibitor	43	0.9803
897	Beta-Phosphoglucomutase inhibitor	5	0.9990
898	Beta-ureidopropionase inhibitor	16	0.9702
899	Bile-salt sulfotransferase inhibitor	4	0.9867
900	Biliary tract disorders treatment	94	0.8916
901	Bilirubin oxidase inhibitor	9	0.9172
902	Biliverdin reductase inhibitor	11	0.9936
903	Biotin carboxylase inhibitor	4	0.9862
904	Biotin-[methylmalonyl-CoA-carboxytransferase] ligase inhibitor	4	0.9996
905	Biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase inhibitor	3	0.9783
906	Biotin-CoA ligase inhibitor	3	0.9894
907	Biotinidase inhibitor	8	0.8388
908	Biphenyl-2,3-diol 1,2-dioxygenase inhibitor	15	0.9906
909	Bipolar disorder treatment	192	0.9633
910	Bis(5'-adenosyl)-triphosphatase inhibitor	4	0.9908
911	Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) inhibitor	12	0.9960
912	Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) inhibitor	11	0.9964
913	Bisphosphoglycerate mutase inhibitor	4	0.9843
914	Bisphosphoglycerate phosphatase inhibitor	5	0.9697
915	Bisphosphonate	55	0.9996
916	Blasticidin-S deaminase inhibitor	4	0.9776
917	Bombesin 1 receptor antagonist	10	0.9934
918	Bombesin 2 receptor antagonist	19	0.9812
919	Bombesin 3 receptor agonist	24	0.9948
920	Bombesin agonist	25	0.9960
921	Bombesin antagonist	148	0.9888
922	Bone diseases treatment	3281	0.9229
923	Bone formation stimulant	476	0.9203
924	Bone morphogenic protein 1 inhibitor	146	0.9997
925	Bone morphogenic protein inhibitor	148	0.9989
926	Bontoxilysin inhibitor	6	0.9511
927	Bothrolysin inhibitor	3	0.9824
928	Botulin neurotoxin A light chain inhibitor	11	0.8695
929	Botulinum neurotoxin type B inhibitor	8	1.0000
930	Brachyurin inhibitor	8	0.9774
931	Bradycardic	275	0.8012
932	Bradykinin agonist	15	0.9991
933	Bradykinin antagonist	1208	0.9957
934	Bradykinin B1 receptor agonist	6	1.0000
935	Bradykinin B1 receptor antagonist	568	0.9972
936	Bradykinin B2 receptor agonist	9	0.9997
937	Bradykinin B2 receptor antagonist	545	0.9990
938	BRAF expression inhibitor	4	0.9900
939	Branched-chain-amino-acid transaminase inhibitor	21	0.9943
940	Breast cancer-resistant protein inhibitor	39	0.9778
941	Bronchoconstrictor	198	0.8132
942	Bronchodilator	1813	0.9585
943	Bruton tyrosine kinase inhibitor	70	0.9609
944	Bulimia treatment	103	0.9973
945	Bullous pemphigoid	8	0.9616
946	Butyrate-CoA ligase inhibitor	10	0.9885
947	Butyrylcholinesterase inhibitor	952	0.9890
948	Butyrylcholinesterase stimulant	3	0.9992
949	Butyryl-CoA dehydrogenase inhibitor	9	0.9963
950	Ca(v)2.2 blocker	344	0.9835
951	Ca2+/calmodulin-dependent kinase I inhibitor	18	0.9146
952	Ca2+/calmodulin-dependent kinase II inhibitor	86	0.9606
953	Ca2+/calmodulin-dependent protein kinase inhibitor	96	0.9198
954	Ca2+-transporting ATPase inhibitor	12	0.8608
955	Cachexia treatment	140	0.9415
956	Cadherin antagonist	3	0.9996
957	Calcineurin inhibitor	13	0.9996
958	Calcitonin gene-related peptide 1 receptor antagonist	256	0.9968
959	Calcitonin gene-related peptide antagonist	649	0.9962
960	Calcitonin stimulant	17	0.9664
961	Calcium antagonist	72	0.9576
962	Calcium channel (voltage-sensitive) activator	6	0.8068
963	Calcium channel (voltage-sensitive) blocker	2248	0.9617
964	Calcium channel activator	49	0.9153
965	Calcium channel blocker	4357	0.9548
966	Calcium channel L-type blocker	1379	0.9857
967	Calcium channel N-type blocker	623	0.9510
968	Calcium channel T-type blocker	344	0.9834
969	Calcium regulator	259	0.8387
970	Calcium release-activated channel blocker	51	0.9967
971	Calcium-sensing receptor agonist	5	0.9847
972	Calcium-sensing receptor antagonist	87	0.9924
973	Calpain inhibitor	863	0.9326
974	Camphor 1,2-monooxygenase inhibitor	4	0.9845
975	Cancer associated disorders treatment	49	0.8612
976	Cancer procoagulant inhibitor	11	0.9750
977	Candidapepsin 2 inhibitor	10	0.9999
978	Candidapepsin inhibitor	17	0.9723
979	Cannabinoid receptor antagonist	1962	0.9902
980	Capillary fragility treatment	18	0.9700
981	Carbamoyl-phosphate synthase (ammonia) inhibitor	15	0.9903
982	Carbamoyl-serine ammonia-lyase inhibitor	3	0.9990
983	Carbonic anhydrase I inhibitor	812	0.9989
984	Carbonic anhydrase I stimulant	56	0.9995
985	Carbonic anhydrase II inhibitor	1211	0.9981
986	Carbonic anhydrase II stimulant	59	0.9929
987	Carbonic anhydrase inhibitor	1344	0.9976
988	Carbonic anhydrase IV inhibitor	810	0.9989
989	Carbonic anhydrase IV stimulant	50	0.9999
990	Carbonic anhydrase IX inhibitor	156	0.9990
991	Carbonic anhydrase stimulant	74	0.9912
992	Carbonic anhydrase V inhibitor	75	0.9905
993	Carbonic anhydrase VII inhibitor	22	0.9985
994	Carbonic anhydrase XII inhibitor	34	0.9993
995	Carbonic anhydrase XIV inhibitor	18	0.9792
996	Carbonic anhydrase XV inhibitor	3	1.0000
997	Carbon-monoxide dehydrogenase inhibitor	3	0.9756
998	Carboxy-cis,cis-muconate cyclase inhibitor	19	0.9979
999	Carboxycyclohexadienyl dehydratase inhibitor	5	0.9999
1000	Carboxylate reductase inhibitor	6	0.9976
1001	Carboxylesterase inhibitor	43	0.9798
1002	Carboxymethylenebutenolidase inhibitor	3	0.9944
1003	Carboxypeptidase B inhibitor	39	0.9958
1004	Carboxypeptidase D inhibitor	9	0.9528
1005	Carboxypeptidase E inhibitor	21	0.9448
1006	Carboxypeptidase M inhibitor	6	0.9960
1007	Carboxypeptidase Taq inhibitor	3	0.9263
1008	Carboxypeptidase U inhibitor	17	0.9934
1009	Carcinogenic	1813	0.9329
1010	Carcinogenic, group 1	23	0.8685
1011	Carcinogenic, group 2A	36	0.9549
1012	Carcinogenic, group 2B	194	0.9602
1013	Carcinogenic, group 3	387	0.9479
1014	Carcinogenic, mouse	456	0.9210
1015	Carcinogenic, mouse, female	384	0.9152
1016	Carcinogenic, mouse, male	365	0.9298
1017	Carcinogenic, rat	603	0.9314
1018	Carcinogenic, rat, female	445	0.9249
1019	Carcinogenic, rat, male	511	0.9305
1020	Cardiac myosin stimulant	4	1.0000
1021	Cardiodepressant	160	0.9148
1022	Cardioprotectant	187	0.8845
1023	Cardiotonic	3225	0.8896
1024	Cardiovascular analeptic	18	0.9339
1025	Carminative	4	0.9778
1026	Carnitinamidase inhibitor	7	0.9571
1027	Carnitine 3-dehydrogenase inhibitor	11	0.9846
1028	Carnitine dehydratase inhibitor	4	0.9921
1029	Carnitine O-octanoyltransferase inhibitor	7	0.9833
1030	Carnitine palmitoyltransferase inhibitor	23	0.9830
1031	Carnosine synthase inhibitor	14	0.9575
1032	Caspase 2 inhibitor	13	0.9468
1033	Caspase 3 inhibitor	629	0.9655
1034	Caspase 3 stimulant	83	0.8102
1035	Caspase 6 inhibitor	126	0.9992
1036	Caspase 7 inhibitor	303	0.9996
1037	Caspase 8 inhibitor	242	0.9935
1038	Caspase 8 stimulant	31	0.8330
1039	Caspase 9 inhibitor	37	0.9686
1040	Catalase inhibitor	27	0.9607
1041	Catalase stimulant	53	0.9270
1042	Cataract	115	0.8204
1043	Catechol 1,2-dioxygenase inhibitor	20	0.9909
1044	Catechol 2,3-dioxygenase inhibitor	32	0.9946
1045	Catechol O methyltransferase inhibitor	58	0.9816
1046	Catechol oxidase inhibitor	15	0.9748
1047	Catenin beta inhibitor	35	0.8642
1048	Cathepsin B inhibitor	665	0.9863
1049	Cathepsin D inhibitor	605	0.9802
1050	Cathepsin E inhibitor	38	0.9662
1051	Cathepsin F inhibitor	29	0.9761
1052	Cathepsin G inhibitor	97	0.9593
1053	Cathepsin H inhibitor	43	0.9396
1054	Cathepsin K inhibitor	661	0.9987
1055	Cathepsin L inhibitor	671	0.9858
1056	Cathepsin S inhibitor	649	0.9952
1057	Cathepsin T inhibitor	7	0.9472
1058	Cathepsin V inhibitor	31	0.9982
1059	CC chemokine 1 receptor antagonist	298	0.9948
1060	CC chemokine 10 receptor antagonist	10	1.0000
1061	CC chemokine 2 receptor antagonist	413	0.9857
1062	CC chemokine 3 receptor antagonist	339	0.9934
1063	CC chemokine 4 receptor antagonist	55	0.9521
1064	CC chemokine 5 receptor agonist	14	0.9998
1065	CC chemokine 5 receptor antagonist	461	0.9881
1066	CC chemokine 9 receptor antagonist	23	0.9762
1067	CC chemokine receptor 2B antagonist	3	0.9590
1068	CC chemokine receptor agonist	15	0.9840
1069	CC chemokine receptor antagonist	1506	0.9806
1070	CD45 antagonist	96	0.9789
1071	CD80 antagonist	81	1.0000
1072	CDC25 phosphatase inhibitor	32	0.9937
1073	CDC25A inhibitor	90	0.9740
1074	CDC25B inhibitor	147	0.9820
1075	CDC25C inhibitor	32	0.9670
1076	CDC7 inhibitor	94	0.9956
1077	CDK/Cyclin complex inhibitor	1090	0.9791
1078	CDK1/cyclin B inhibitor	307	0.9910
1079	CDK2/cyclin A inhibitor	379	0.9640
1080	CDK2/cyclin A3 inhibitor	30	1.0000
1081	CDK2/cyclin E inhibitor	439	0.9923
1082	CDK4/cyclin D inhibitor	425	0.9955
1083	CDK4/cyclin D1 inhibitor	249	0.9878
1084	CDK4/cyclin D3 inhibitor	7	1.0000
1085	CDK5/p25 inhibitor	48	0.9855
1086	CDK9/cyclin T1 inhibitor	7	0.8531
1087	CDP-4-dehydro-6-deoxyglucose reductase inhibitor	4	0.9856
1088	CDP-diacylglycerol diphosphatase inhibitor	6	0.9993
1089	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase inhibitor	3	0.9776
1090	CDP-diacylglycerol-inositol 3-phosphatidyltransferase inhibitor	15	0.9225
1091	CDP-diacylglycerol-serine O-phosphatidyltransferase inhibitor	6	0.9077
1092	CDP-glycerol diphosphatase inhibitor	6	0.9999
1093	CDP-glycerol glycerophosphotransferase inhibitor	4	0.8338
1094	Celiac disease treatment	47	0.9780
1095	Cell adhesion inhibitor	681	0.9582
1096	Cell adhesion molecule inhibitor	135	0.8599
1097	Cell wall biosynthesis inhibitor	20	0.8851
1098	Cell wall synthesis inhibitor	443	0.9599
1099	Cellobiose phosphorylase inhibitor	10	0.9929
1100	Cellulase inhibitor	12	0.9732
1101	Cellulose 1,4-beta-cellobiosidase inhibitor	11	0.8941
1102	Cellulose synthase (UDP-forming) inhibitor	13	0.8970
1103	Centromere associated protein inhibitor	7	0.9048
1104	Ceramidase inhibitor	12	0.9982
1105	Ceramide glucosyltransferase inhibitor	18	0.9537
1106	Cerebroside-sulfatase inhibitor	9	0.9807
1107	Cerebrovascular disordes treatment	478	0.9238
1108	Cerevisin inhibitor	8	0.9884
1109	CF transmembrane conductance regulator agonist	8	0.8484
1110	CF transmembrane conductance regulator antagonist	35	0.9731
1111	Chalcone isomerase inhibitor	26	0.9952
1112	Channel-conductance-controlling ATPase inhibitor	5	0.9639
1113	Chaperonin ATPase inhibitor	6	0.9652
1114	Check point kinase 1 inhibitor	488	0.9899
1115	Check point kinase 2 inhibitor	121	0.9856
1116	Check point kinase inhibitor	567	0.9893
1117	Chelator	117	0.9721
1118	Chelator, Iron	37	0.9963
1119	Chemokine receptor agonist	15	0.9840
1120	Chemokine receptor antagonist	2247	0.9784
1121	Chemopreventive	345	0.9419
1122	Chemoprotective	194	0.9141
1123	Chemosensitizer	203	0.8432
1124	Chenodeoxycholoyltaurine hydrolase inhibitor	3	0.9634
1125	Chitin deacetylase inhibitor	3	0.9994
1126	Chitin synthase inhibitor	31	0.9440
1127	Chitinase inhibitor	29	0.8941
1128	Chitobiosyldiphosphodolichol beta-mannosyltransferase inhibitor	5	0.9834
1129	Chitosanase inhibitor	8	0.9455
1130	Chloramphenicol O-acetyltransferase inhibitor	5	0.9954
1131	Chlordecone reductase inhibitor	4	0.9112
1132	Chloride channel activator	41	0.8813
1133	Chloride channel blocker	10	0.9503
1134	Chloride peroxidase inhibitor	3	0.8850
1135	Chloride/bicarbonate exchanger inhibitor	24	0.9915
1136	Cholate-CoA ligase inhibitor	9	0.9879
1137	Cholecystokinin A agonist	104	0.9993
1138	Cholecystokinin A antagonist	1477	0.9947
1139	Cholecystokinin agonist	109	0.9991
1140	Cholecystokinin antagonist	2074	0.9931
1141	Cholecystokinin B antagonist	1501	0.9946
1142	Choleretic	116	0.9383
1143	Cholestanetriol 26-monooxygenase inhibitor	9	0.9124
1144	Cholestasis	206	0.8288
1145	Cholestenol delta-isomerase inhibitor	8	0.9997
1146	Cholestenone 5alpha-reductase inhibitor	12	0.9174
1147	Cholesterol absorption inhibitor	192	0.9765
1148	Cholesterol antagonist	119	0.8763
1149	Cholesterol ester transfer protein antagonist	572	0.9931
1150	Cholesterol esterase inhibitor	183	0.9953
1151	Cholesterol monooxygenase (side-chain-cleaving) inhibitor	7	1.0000
1152	Cholesterol oxidase inhibitor	15	0.9837
1153	Cholesterol synthesis inhibitor	81	0.9672
1154	Choline acetyltransferase stimulant	5	0.9341
1155	Choline dehydrogenase inhibitor	5	0.9941
1156	Choline kinase inhibitor	12	0.9267
1157	Choline sulfotransferase inhibitor	20	0.9886
1158	Choline-phosphate cytidylyltransferase inhibitor	15	0.8990
1159	Cholinergic	3980	0.9615
1160	Cholinergic antagonist	4093	0.9704
1161	Choline-sulfatase inhibitor	8	0.9743
1162	Choloylglycine hydrolase inhibitor	3	0.9849
1163	Chondroitin 6-sulfotransferase inhibitor	4	0.9883
1164	Chorea	45	0.8993
1165	Choreoathetosis	29	0.8850
1166	Chorismate mutase inhibitor	22	0.9978
1167	Chronic obstructive pulmonary disease treatment	2161	0.9326
1168	Chymase inhibitor	177	0.9895
1169	Chymosin inhibitor	3	0.8770
1170	Chymotrypsin inhibitor	249	0.9718
1171	Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase inhibitor	3	0.9693
1172	Citrate (Si)-synthase inhibitor	26	0.9918
1173	Clavaminate synthase inhibitor	3	0.9747
1174	Cleft palate	9	0.8488
1175	Clostripain inhibitor	22	0.9424
1176	Cl--transporting ATPase inhibitor	5	0.8936
1177	CMP-KDO synthase inhibitor	3	0.9992
1178	CMP-N-acetylneuraminate monooxygenase inhibitor	13	0.9702
1179	CMP-N-acylneuraminate phosphodiesterase inhibitor	23	0.9859
1180	CNS active muscle relaxant	140	0.9665
1181	Coactivator-associated arginine methyltransferase 1 inhibitor	5	0.8750
1182	Coagulant	22	0.9765
1183	Cocain dependency treatment	201	0.9616
1184	Coccolysin inhibitor	11	0.9052
1185	Coenzyme-B sulfoethylthiotransferase inhibitor	3	0.8743
1186	Cognition disorders treatment	6742	0.8971
1187	Collagenase 3 inhibitor	1699	0.9900
1188	Collagenase inhibitor	753	0.9881
1189	Colony stimulating factor agonist	36	0.9498
1190	Colony stimulating factor antagonist	278	0.9712
1191	Colorectum cell-derived growth factor antagonist	5	1.0000
1192	Coma	311	0.8260
1193	CO-methylating acetyl-CoA synthase inhibitor	3	1.0000
1194	Complement C5a chemotactic receptor antagonist	103	0.9886
1195	Complement C5a convertase stimulant	3	1.0000
1196	Complement factor 1 inhibitor	34	0.9503
1197	Complement factor 1r inhibitor	31	0.9991
1198	Complement factor D inhibitor	3	0.8511
1199	Complement inhibitor	51	0.8929
1200	Complement stimulant	3	1.0000
1201	Conjunctivitis	341	0.7731
1202	Consciousness alteration	571	0.8078
1203	Constipation treatment	92	0.9469
1204	Contraceptive	791	0.9535
1205	Contraceptive female	119	0.9307
1206	Contraceptive male	177	0.9681
1207	Coproporphyrinogen oxidase inhibitor	28	0.9844
1208	Corneal wound healing stimulator	11	0.9883
1209	Corticosteroid antagonist	3	0.9245
1210	Corticosteroid side-chain-isomerase inhibitor	5	0.9693
1211	Corticosteroid-like	52	0.9986
1212	Corticotropin releasing factor 1 receptor antagonist	733	0.9997
1213	Corticotropin releasing factor antagonist	33	0.9850
1214	Corticotropin-like	3	0.9908
1215	Cortisol sulfotransferase inhibitor	14	0.9980
1216	Cortisone alpha-reductase inhibitor	4	0.9999
1217	Cortisone beta-reductase inhibitor	7	0.9993
1218	CPB protease inhibitor	3	0.9994
1219	CpG-Oligodeoxynucleotides inhibitor	27	1.0000
1220	Creatinase inhibitor	8	0.9916
1221	Creatine kinase inhibitor	30	0.9738
1222	Creatininase inhibitor	6	0.9013
1223	Creatinine deaminase inhibitor	3	0.9911
1224	Crotonoyl-[acyl-carrier-protein] hydratase inhibitor	3	0.9842
1225	Cruzipain inhibitor	168	0.9779
1226	c-Src kinase inhibitor	1446	0.9824
1227	CTGF expression inhibitor	11	0.9480
1228	CTP synthase inhibitor	14	0.9864
1229	Cushing's syndrome treatment	76	0.9699
1230	Cutinase inhibitor	6	0.9687
1231	CXC chemokine 1 receptor antagonist	113	0.9933
1232	CXC chemokine 2 receptor antagonist	124	0.9839
1233	CXC chemokine 3 receptor antagonist	155	0.9926
1234	CXC chemokine 4 receptor antagonist	145	0.9940
1235	CXC chemokine 5 receptor antagonist	328	0.9999
1236	CXC chemokine L1/GRO-alpha antagonist	17	1.0000
1237	CXC chemokine receptor antagonist	869	0.9888
1238	Cyanate hydratase inhibitor	13	0.9862
1239	Cyanoalanine nitrilase inhibitor	5	0.8426
1240	Cyanosis	162	0.8357
1241	Cyclamate sulfohydrolase inhibitor	4	0.9906
1242	Cyclic AMP agonist	15	0.8708
1243	Cyclic AMP modulator	40	0.8940
1244	Cyclic AMP phosphodiesterase inhibitor	188	0.8747
1245	Cyclic GMP phosphodiesterase inhibitor	19	0.8800
1246	Cyclin-dependent kinase 1 inhibitor	1143	0.9856
1247	Cyclin-dependent kinase 2 inhibitor	2002	0.9832
1248	Cyclin-dependent kinase 4 inhibitor	958	0.9903
1249	Cyclin-dependent kinase 5 inhibitor	700	0.9902
1250	Cyclin-dependent kinase 6 inhibitor	53	0.9663
1251	Cyclin-dependent kinase 7 inhibitor	53	0.9652
1252	Cyclin-dependent kinase 9 inhibitor	63	0.9825
1253	Cyclin-dependent kinase inhibitor	3665	0.9779
1254	Cycloartenol synthase inhibitor	19	0.9654
1255	Cyclohexadienyl dehydrogenase inhibitor	12	0.9993
1256	Cyclohexanone monooxygenase inhibitor	11	0.8499
1257	Cyclohexyl-isocyanide hydratase inhibitor	3	0.9812
1258	Cyclomaltodextrin glucanotransferase inhibitor	17	0.9995
1259	Cyclomaltodextrinase inhibitor	6	0.8355
1260	Cyclooxygenase 1 inhibitor	1376	0.9737
1261	Cyclooxygenase 1 substrate	3	0.9957
1262	Cyclooxygenase 2 inhibitor	3370	0.9772
1263	Cyclooxygenase 3 inhibitor	18	0.9972
1264	Cyclooxygenase inhibitor	4216	0.9660
1265	Cyclooxygenase substrate	15	0.9085
1266	Cyclopentanone monooxygenase inhibitor	5	0.9791
1267	Cyclopropane-fatty-acyl-phospholipid synthase inhibitor	10	0.9503
1268	CYP11B substrate	7	1.0000
1269	CYP11B1 inhibitor	313	0.9915
1270	CYP11B1 substrate	3	1.0000
1271	CYP11B2 inhibitor	315	0.9980
1272	CYP11B2 substrate	6	1.0000
1273	CYP17 inhibitor	7	0.9396
1274	CYP17 substrate	10	0.9857
1275	CYP17A substrate	4	0.9999
1276	CYP19 inducer	3	1.0000
1277	CYP19 inhibitor	43	0.9640
1278	CYP19 substrate	23	0.9742
1279	CYP19A1 expression inhibitor	24	0.8452
1280	CYP19A1 substrate	12	1.0000
1281	CYP1A inducer	45	0.9169
1282	CYP1A inhibitor	435	0.8861
1283	CYP1A substrate	620	0.8871
1284	CYP1A1 inducer	30	0.9603
1285	CYP1A1 inhibitor	83	0.9216
1286	CYP1A1 substrate	328	0.9196
1287	CYP1A2 inducer	24	0.8894
1288	CYP1A2 inhibitor	412	0.8901
1289	CYP1A2 substrate	477	0.8823
1290	CYP1A3 substrate	5	0.9954
1291	CYP1B substrate	83	0.9315
1292	CYP1B1 inducer	9	0.9991
1293	CYP1B1 inhibitor	62	0.9750
1294	CYP1B1 substrate	81	0.9427
1295	CYP24 inhibitor	11	0.9121
1296	CYP24 substrate	14	0.9763
1297	CYP26 inhibitor	19	0.9931
1298	CYP26 substrate	5	0.9492
1299	CYP26A substrate	4	0.9356
1300	CYP27 substrate	14	0.9835
1301	CYP27A substrate	12	0.9798
1302	CYP27A1 inhibitor	9	0.9995
1303	CYP27A1 substrate	8	0.9999
1304	CYP2A substrate	228	0.8866
1305	CYP2A1 substrate	16	0.8611
1306	CYP2A10 substrate	4	0.9785
1307	CYP2A11 substrate	3	0.9754
1308	CYP2A13 substrate	3	0.9996
1309	CYP2A2 substrate	8	0.9586
1310	CYP2A3 substrate	14	0.9598
1311	CYP2A4 substrate	3	0.9069
1312	CYP2A5 inhibitor	34	0.9959
1313	CYP2A5 substrate	8	0.9369
1314	CYP2A6 inhibitor	78	0.9611
1315	CYP2A6 substrate	200	0.8818
1316	CYP2A8 substrate	3	0.9558
1317	CYP2B substrate	442	0.9121
1318	CYP2B1 substrate	179	0.9487
1319	CYP2B10 substrate	3	0.8610
1320	CYP2B11 substrate	10	0.9274
1321	CYP2B18 substrate	4	0.8620
1322	CYP2B2 substrate	77	0.9118
1323	CYP2B4 substrate	37	0.9841
1324	CYP2B5 substrate	3	0.9534
1325	CYP2B6 substrate	213	0.8888
1326	CYP2C substrate	564	0.8703
1327	CYP2C10 substrate	18	0.9300
1328	CYP2C11 substrate	86	0.9131
1329	CYP2C12 substrate	10	0.8496
1330	CYP2C18 inhibitor	13	0.9830
1331	CYP2C18 substrate	35	0.9206
1332	CYP2C19 inducer	8	0.8330
1333	CYP2C19 inhibitor	361	0.8825
1334	CYP2C19 substrate	275	0.8897
1335	CYP2C2 substrate	5	0.9583
1336	CYP2C29 substrate	5	0.8303
1337	CYP2C3 substrate	6	0.8603
1338	CYP2C6 substrate	53	0.9087
1339	CYP2C8 inducer	9	0.9708
1340	CYP2C8 inhibitor	55	0.8136
1341	CYP2C8 substrate	170	0.8477
1342	CYP2C9 inducer	27	0.8199
1343	CYP2C9 inhibitor	748	0.9007
1344	CYP2C9 substrate	342	0.8723
1345	CYP2D substrate	461	0.8888
1346	CYP2D1 substrate	37	0.9439
1347	CYP2D15 substrate	5	0.8161
1348	CYP2D16 substrate	3	0.9175
1349	CYP2D2 inhibitor	7	0.9295
1350	CYP2D6 inhibitor	994	0.9359
1351	CYP2D6 substrate	438	0.8882
1352	CYP2E substrate	370	0.9073
1353	CYP2E1 inducer	12	0.8612
1354	CYP2E1 inhibitor	61	0.9526
1355	CYP2E1 substrate	364	0.9077
1356	CYP2F1 substrate	8	0.9452
1357	CYP2G1 substrate	11	0.9626
1358	CYP2H substrate	3	0.8461
1359	CYP2J substrate	5	0.8653
1360	CYP2J2 substrate	4	0.8625
1361	CYP3A inducer	74	0.8729
1362	CYP3A substrate	993	0.8528
1363	CYP3A1 substrate	48	0.8599
1364	CYP3A11 substrate	4	0.9992
1365	CYP3A2 substrate	59	0.8184
1366	CYP3A3 substrate	36	0.8504
1367	CYP3A4 inducer	70	0.8669
1368	CYP3A4 inhibitor	1396	0.9110
1369	CYP3A4 substrate	840	0.8479
1370	CYP3A5 inducer	4	0.9753
1371	CYP3A5 substrate	125	0.8508
1372	CYP3A7 substrate	41	0.8857
1373	CYP3C substrate	7	0.9867
1374	CYP4A substrate	39	0.8738
1375	CYP4A1 substrate	8	0.9914
1376	CYP4A11 substrate	17	0.8699
1377	CYP4A2 substrate	4	0.9750
1378	CYP4B substrate	16	0.9451
1379	CYP4B1 substrate	15	0.9446
1380	CYP4F substrate	21	0.9817
1381	CYP4F12 substrate	7	0.9652
1382	CYP4F2 inhibitor	34	0.9951
1383	CYP4F2 substrate	9	0.9490
1384	CYP4F3 substrate	10	0.9999
1385	CYP4F8 substrate	4	0.9997
1386	CYP51 inhibitor	14	0.9979
1387	CYP7 inhibitor	7	0.8234
1388	CYP7 substrate	8	0.9999
1389	CYP7A1 substrate	5	1.0000
1390	CYP7B substrate	4	0.9997
1391	CYP7B1 substrate	4	0.9997
1392	Cystathionine beta-lyase inhibitor	21	0.9876
1393	Cystathionine beta-synthase inhibitor	12	0.9897
1394	Cystathionine gamma-lyase inhibitor	26	0.9899
1395	Cysteamine dioxygenase inhibitor	9	0.9802
1396	Cysteine desulfurase inhibitor	5	0.9910
1397	Cysteine dioxygenase inhibitor	16	0.9980
1398	Cysteine protease B inhibitor	12	0.9998
1399	Cysteine synthase inhibitor	20	0.9345
1400	Cysteine transaminase inhibitor	3	0.9971
1401	Cysteine-S-conjugate beta-lyase inhibitor	3	0.9938
1402	Cysteine-tRNA ligase inhibitor	19	0.9907
1403	Cystic fibrosis treatment	231	0.8626
1404	Cystinyl aminopeptidase inhibitor	35	0.9435
1405	Cytidine deaminase inhibitor	511	0.9648
1406	Cytidylate kinase inhibitor	19	0.9965
1407	Cytochrome P450 inhibitor	3256	0.9077
1408	Cytochrome P450 stimulant	17	0.8168
1409	Cytochrome-b5 reductase inhibitor	21	0.8724
1410	Cytochrome-b5 reductase substrate	3	0.8905
1411	Cytochrome-c3 hydrogenase inhibitor	6	0.9941
1412	Cytokine modulator	140	0.9512
1413	Cytokine production inhibitor	757	0.9582
1414	Cytokine production stimulant	260	0.9853
1415	Cytokine release inhibitor	7	0.9888
1416	Cytoprotectant	37	0.8419
1417	Cytosine deaminase inhibitor	27	0.9769
1418	Cytosol alanyl aminopeptidase inhibitor	43	0.9435
1419	Cytosole dipeptidase inhibitor	5	0.9905
1420	Cytosolic phospholipase A2 inhibitor	151	0.9927
1421	Cytostatic	320	0.9112
1422	Cytotoxic	721	0.9308
1423	D(-)-tartrate dehydratase inhibitor	5	0.9995
1424	D-2-hydroxy-acid dehydrogenase inhibitor	6	0.9920
1425	Dactylysin inhibitor	22	0.9223
1426	D-Ala-D-Ala ligase inhibitor	6	0.9581
1427	D-alanine 2-hydroxymethyltransferase inhibitor	3	0.9850
1428	D-alanine transaminase inhibitor	18	0.9914
1429	D-Alanine-alanyl-poly(glycerolphosphate) ligase inhibitor	5	0.9998
1430	D-Alanine-poly(phosphoribitol) ligase inhibitor	5	0.9990
1431	D-amino-acid dehydrogenase inhibitor	5	0.9656
1432	D-Amino-acid oxidase inhibitor	36	0.9990
1433	D-arabinonolactone oxidase inhibitor	5	0.9915
1434	D-aspartate oxidase inhibitor	18	0.9987
1435	D-benzoylarginine-4-nitroanilide amidase inhibitor	5	0.9953
1436	dCMP deaminase inhibitor	19	0.9970
1437	dCTP deaminase inhibitor	10	0.9972
1438	dCTP diphosphatase inhibitor	3	1.0000
1439	D-cysteine desulfhydrase inhibitor	5	0.9911
1440	Deacetoxycephalosporin-C synthase inhibitor	10	0.9908
1441	Decylcitrate synthase inhibitor	4	0.9777
1442	Dehydro-L-gulonate decarboxylase inhibitor	3	0.9469
1443	Delayed rectifier potassium channel activator	162	0.9916
1444	Delayed rectifier potassium channel blocker	56	0.9951
1445	Delirium	103	0.8240
1446	DELTA14-sterol reductase inhibitor	13	0.8945
1447	DELTA24-sterol reductase inhibitor	7	0.8779
1448	Dementia treatment	13	0.8507
1449	Demethylmacrocin O-methyltransferase inhibitor	10	0.9998
1450	Demethylsterigmatocystin 6-O-methyltransferase inhibitor	3	0.9891
1451	Demyelination	9	0.9305
1452	Deoxyadenosine kinase inhibitor	13	0.9212
1453	Deoxycytidine deaminase inhibitor	5	0.9911
1454	Deoxycytidine kinase inhibitor	43	0.9747
1455	Deoxycytidylate 5-hydroxymethyltransferase inhibitor	7	0.9788
1456	Deoxyguanosine kinase inhibitor	37	0.9961
1457	Deoxyhypusine monooxygenase inhibitor	16	0.9983
1458	Deoxyhypusine synthase inhibitor	27	0.9864
1459	Deoxynucleoside kinase inhibitor	24	0.9998
1460	Deoxyribonuclease (pyrimidine dimer) inhibitor	3	0.9985
1461	Deoxyribonuclease I inhibitor	10	0.9498
1462	Deoxyribonuclease X inhibitor	3	0.9929
1463	Deoxyribose-phosphate aldolase inhibitor	4	0.9909
1464	Dependence	70	0.8414
1465	Dependence treatment	1217	0.9398
1466	Depression	125	0.8172
1467	Dermatitis	875	0.8179
1468	Dermatologic	3457	0.8876
1469	Dethiobiotin synthase inhibitor	7	0.9871
1470	Dextranase inhibitor	9	0.9477
1471	Dextransucrase inhibitor	18	0.9939
1472	D-glutamate oxidase inhibitor	9	0.9906
1473	Diabetes insipidus treatment	30	0.9982
1474	Diabetic nephropathy treatment	66	0.9004
1475	Diabetic neuropathy treatment	57	0.8156
1476	Diabetic retinopathy treatment	267	0.9318
1477	Diacylglycerol cholinephosphotransferase inhibitor	28	0.9789
1478	Diacylglycerol kinase inhibitor	23	0.9394
1479	Diacylglycerol O-acyltransferase 1 inhibitor	93	0.9977
1480	Diacylglycerol O-acyltransferase inhibitor	141	0.9848
1481	Diamine N-acetyltransferase inhibitor	12	0.9461
1482	Diamine oxidase inhibitor	32	0.9901
1483	Diaminopimelate decarboxylase inhibitor	13	0.9995
1484	Diaminopimelate dehydrogenase inhibitor	7	0.9926
1485	Diaminopimelate epimerase inhibitor	8	0.9987
1486	Diaminopropionate ammonia-lyase inhibitor	11	0.9919
1487	Diarrhea	316	0.8166
1488	Dichloromethane dehalogenase inhibitor	9	0.9996
1489	Dichloromuconate cycloisomerase inhibitor	4	0.9961
1490	Diguanidinobutanase inhibitor	6	0.9940
1491	Dihydrodipicolinate reductase inhibitor	8	0.8953
1492	Dihydrodipicolinate synthase inhibitor	16	0.9944
1493	Dihydrofolate reductase (Mycobacterium avium) inhibitor	11	0.9997
1494	Dihydrofolate reductase (Pneumocystis carinii) inhibitor	8	0.9999
1495	Dihydrofolate reductase (Toxoplasma gondii) inhibitor	11	0.9993
1496	Dihydrofolate reductase inhibitor	1812	0.9927
1497	Dihydrofolate synthase inhibitor	13	0.9324
1498	Dihydrolipoamide S-acetyltransferase inhibitor	4	0.9938
1499	Dihydroneopterin aldolase inhibitor	35	0.9997
1500	Dihydroorotase inhibitor	16	0.9693
1501	Dihydroorotate dehydrogenase inhibitor	196	0.9868
1502	Dihydroorotate oxidase inhibitor	84	0.9869
1503	Dihydropteroate synthase inhibitor	31	0.9864
1504	Dihydropyrimidinase inhibitor	15	0.9900
1505	Dihydropyrimidine dehydrogenase inhibitor	8	0.9852
1506	Dihydrouracil dehydrogenase (NAD+) inhibitor	5	0.9140
1507	Dihydrouracil oxidase inhibitor	8	0.9899
1508	Dihydroxyacetanilide dehydrogenase inhibitor	5	0.9997
1509	Dihydroxyacetanilide epoxidase inhibitor	5	0.9997
1510	Dihydroxy-acid dehydratase inhibitor	14	0.9469
1511	Diiodophenylpyruvate reductase inhibitor	3	0.9961
1512	Diiodotyrosine transaminase inhibitor	6	0.9991
1513	Diisopropyl-fluorophosphatase inhibitor	5	0.9906
1514	Dimethylallyltranstransferase inhibitor	19	0.9687
1515	Dimethylargininase inhibitor	3	0.9295
1516	Dimethylhistidine N-methyltransferase inhibitor	5	0.9923
1517	Dimethylmaleate hydratase inhibitor	3	0.9809
1518	Dipeptidase E inhibitor	4	0.9349
1519	Dipeptidyl peptidase I inhibitor	68	0.9794
1520	Dipeptidyl peptidase II inhibitor	350	0.9888
1521	Dipeptidyl peptidase inhibitor	1605	0.9880
1522	Dipeptidyl peptidase IV inhibitor	1195	0.9902
1523	Dipeptidyl peptidase IX inhibitor	149	0.9994
1524	Dipeptidyl peptidase VIII inhibitor	207	0.9970
1525	Diphenylpicrylhydrazyl (DPPH) scavenger	3	1.0000
1526	Diphosphate-fructose-6-phosphate 1-phosphotransferase inhibitor	17	0.9973
1527	Diphosphate-serine phosphotransferase inhibitor	8	0.9994
1528	Diphosphomevalonate decarboxylase inhibitor	13	0.9332
1529	Di-trans,poly-cis-decaprenylcistransferase inhibitor	4	0.9777
1530	Diuretic	736	0.9203
1531	Diuretic inhibitor	93	0.8720
1532	Dizziness	719	0.8120
1533	D-lactaldehyde dehydrogenase inhibitor	11	0.8602
1534	D-lactate dehydrogenase (cytochrome) inhibitor	7	0.9910
1535	D-lactate dehydrogenase inhibitor	7	0.8755
1536	D-lactate-2-sulfatase inhibitor	4	0.9990
1537	D-Lysine 5,6-aminomutase inhibitor	22	0.9944
1538	D-malate dehydrogenase (decarboxylating) inhibitor	10	0.9907
1539	DNA damaging	466	0.9633
1540	DNA directed DNA polymerase inhibitor	302	0.9560
1541	DNA directed RNA polymerase inhibitor	543	0.9374
1542	DNA directed RNA polymerase stimulant	9	0.9980
1543	DNA gyrase inhibitor	239	0.9897
1544	DNA helicase inhibitor	41	0.9789
1545	DNA intercalator	582	0.9803
1546	DNA ligase (ATP) inhibitor	21	0.8942
1547	DNA methylase inhibitor	41	0.9730
1548	DNA methyltransferase I inhibitor	10	0.9530
1549	DNA nucleotidylexotransferase inhibitor	21	0.9535
1550	DNA polymerase I inhibitor	25	0.8537
1551	DNA polymerase III inhibitor	83	0.9964
1552	DNA repair enzyme inhibitor	165	0.9717
1553	DNA synthesis inhibitor	292	0.8955
1554	DNA topoisomerase IV inhibitor	110	0.9925
1555	DNA-(apurinic or apyrimidinic site) lyase inhibitor	12	0.9259
1556	DNA-3-methyladenine glycosylase I inhibitor	5	0.9607
1557	DNA-3-methyladenine glycosylase II inhibitor	3	0.9951
1558	DNA-dependent protein kinase inhibitor	309	0.9946
1559	D-Octopine dehydrogenase inhibitor	20	0.9772
1560	Dolichol kinase inhibitor	8	0.9652
1561	Dolichyldiphosphatase inhibitor	3	0.9999
1562	Dolichyl-diphosphooligosaccharide-protein glycotransferase inhibitor	3	0.9217
1563	Dolichyl-phosphatase inhibitor	6	0.9869
1564	Dolichyl-phosphate beta-D-mannosyltransferase (T. brucei) inhibitor	3	1.0000
1565	Dolichyl-phosphate beta-D-mannosyltransferase inhibitor	19	0.9312
1566	Dolichyl-phosphate beta-glucosyltransferase inhibitor	5	0.9145
1567	DOPA decarboxylase inhibitor	10	0.9850
1568	Dopachrome isomerase inhibitor	7	0.9975
1569	Dopamine D1A antagonist	25	0.9994
1570	Dopamine D2 agonist inducer	3	1.0000
1571	Dopamine D2A antagonist	82	0.9858
1572	Dopamine D2B antagonist	31	0.9996
1573	Dopamine D2L antagonist	481	0.9887
1574	Dopamine D2S antagonist	122	0.9622
1575	Dopamine D5 antagonist	281	0.9932
1576	Dopamine precursors	25	0.9995
1577	Dopamine release inhibitor	3	1.0000
1578	Dopamine release stimulant	7	0.9530
1579	Dopamine transporter inhibitor	1221	0.9906
1580	D-Ornithine 4,5-aminomutase inhibitor	5	0.9915
1581	D-proline reductase (dithiol) inhibitor	5	0.9943
1582	Drowsiness	926	0.8185
1583	Dry eye syndrome treatment	46	0.9197
1584	D-Serine ammonia-lyase inhibitor	4	0.9992
1585	D-stereospecific aminopeptidase inhibitor	7	0.9957
1586	dTDP-glucose 4,6-dehydratase inhibitor	6	0.9998
1587	D-threo-aldose 1-dehydrogenase inhibitor	7	0.9369
1588	dTMP kinase (Mycobacterium tuberculosis) inhibitor	11	0.9998
1589	dTMP kinase inhibitor	29	0.9997
1590	Dual specificity phosphatase 1 inhibitor	11	0.9179
1591	Dual specificity phosphatase inhibitor	183	0.9508
1592	Dual specificity protein phosphatase VHR inhibitor	9	0.9990
1593	dUTP diphosphatase inhibitor	14	0.9950
1594	D-xylulose reductase inhibitor	4	0.9858
1595	Dynamin GTPase inhibitor	15	0.9968
1596	Dynein ATPase inhibitor	3	0.9787
1597	Dyrk kinase inhibitor	93	0.9804
1598	Dysarthria	100	0.8333
1599	Dyskinesia	817	0.8407
1600	Dysmenorrhea treatment	166	0.9737
1601	Dyspepsia treatment	74	0.9340
1602	Dysphoria	38	0.8889
1603	Dyspnea	318	0.8619
1604	Dystonia	96	0.8105
1605	Ecdysone 20-monooxygenase inhibitor	15	0.8663
1606	Edema	141	0.8132
1607	Eicosanoid agonist	6	0.9979
1608	EIF4E expression inhibitor	8	0.8337
1609	Elastase 1 inhibitor	58	0.9877
1610	Elastase 2 inhibitor	99	0.9985
1611	Elastase inhibitor	834	0.9877
1612	Electrolyte absorption antagonist	54	0.9547
1613	Electron transport complex I inhibitor	26	0.9849
1614	Electron-transferring-flavoprotein dehydrogenase inhibitor	3	0.8814
1615	Embryotoxic	1743	0.9065
1616	Emetic	788	0.8204
1617	Endo-1,3(4)-beta-glucanase inhibitor	3	0.9913
1618	Endo-1,4-beta-xylanase inhibitor	19	0.9823
1619	Endo-beta-N-acetylglucosaminidase inhibitor	7	0.9998
1620	Endocannabinoid uptake inhibitor	29	0.9920
1621	Endocrine disruptor	223	0.8517
1622	Endoglycosylceramidase inhibitor	4	0.9864
1623	Endometrios treatment	257	0.9763
1624	Endonuclease (influenza) inhibitor	11	0.9927
1625	Endopeptidase inhibitor	87	0.9301
1626	Endopeptidase La inhibitor	39	0.9192
1627	Endopeptidase So inhibitor	7	0.8983
1628	Endothelial growth factor antagonist	9	0.9448
1629	Endothelial nitric-oxide synthase inhibitor	270	0.9974
1630	Endothelin A receptor antagonist	1756	0.9967
1631	Endothelin B receptor antagonist	1423	0.9959
1632	Endothelin receptor agonist	13	0.9997
1633	Endothelin receptor antagonist	2756	0.9951
1634	Endothelin-converting enzyme inhibitor	112	0.9522
1635	Endothiapepsin inhibitor	5	0.9973
1636	Enoyl-[acyl-carrier-protein] reductase (NADH) inhibitor	120	0.9896
1637	Enoyl-CoA hydratase inhibitor	9	0.9954
1638	Enteropeptidase inhibitor	6	0.8343
1639	Envelysin inhibitor	18	0.9508
1640	EphB4 antagonist	280	0.9882
1641	Ephrin antagonist	369	0.9623
1642	Epidermal growth factor antagonist	893	0.9907
1643	Epidermal growth factor receptor kinase inhibitor	2326	0.9627
1644	Epithelial sodium channel blocker	50	0.9921
1645	Epoxide hydrolase 2 inhibitor	281	0.9984
1646	Epoxide hydrolase inhibitor	609	0.9923
1647	Epoxide hydrolase substrate	147	0.9787
1648	Equilibrative nucleoside transport protein 1 inhibitor	97	0.9955
1649	Equilibrative nucleoside transport protein inhibitor	127	0.9955
1650	ErbB antagonist	841	0.9833
1651	ErbB-1 antagonist	12	0.9850
1652	ErbB-2 antagonist	796	0.9836
1653	ErbB-4 antagonist	42	0.9771
1654	Erectile dysfunction treatment	310	0.9453
1655	Erythro-3-hydroxyaspartate ammonia-lyase inhibitor	4	0.9996
1656	Erythropoiesis stimulant	6	0.8483
1657	Erythropoietin receptor agonist	10	0.9999
1658	Estradiol 17 beta dehydrogenase 2 inhibitor	81	0.9773
1659	Estradiol 17 beta dehydrogenase 3 inhibitor	129	0.9954
1660	Estradiol 17 beta dehydrogenase inhibitor	310	0.9865
1661	Estradiol 17 beta dehydrogenase stimulant	19	0.9987
1662	Estradiol 17alpha-dehydrogenase inhibitor	3	0.9903
1663	Estrogen agonist	734	0.9797
1664	Estrogen alpha receptor agonist	44	0.9943
1665	Estrogen antagonist	2227	0.9654
1666	Estrogen beta receptor agonist	185	0.9963
1667	Estrogen receptor beta antagonist	1524	0.9724
1668	Estrogen-related receptor alpha antagonist	43	0.9905
1669	Estrone sulfatase inhibitor	240	0.9970
1670	Estrone sulfotransferase inhibitor	39	0.9673
1671	Estrone sulfotransferase stimulant	17	0.9987
1672	Ethanolamine ammonia-lyase inhibitor	10	0.9994
1673	Ethanolamine kinase inhibitor	15	0.9886
1674	Ethanolamine oxidase inhibitor	6	0.8978
1675	Ethanolamine-phosphate cytidylyltransferase inhibitor	7	0.9305
1676	Ethanolaminephosphotransferase inhibitor	28	0.9608
1677	Ether-a-go-go potassium channel 1 blocker	21	1.0000
1678	Ether-a-go-go potassium channel blocker	21	1.0000
1679	Eukaryotic elongation factor 2 kinase inhibitor	3	1.0000
1680	Euphoria	43	0.8404
1681	Excitability	300	0.8206
1682	Excitatory amino acid transporter 1 inhibitor	33	0.9989
1683	Excitatory amino acid transporter 2 inhibitor	44	0.9994
1684	Excitatory amino acid transporter EAAC1 inhibitor	6	0.9912
1685	Exoribonuclease II inhibitor	5	0.9379
1686	Expectorant	132	0.9329
1687	Extrapyramidal disorders treatment	120	0.9591
1688	Extrapyramidal effect	12	0.8657
1689	Eye irritation, high	528	0.9372
1690	Eye irritation, inactive	91	0.8967
1691	Eye irritation, moderate	229	0.9674
1692	Eye irritation, weak	348	0.9684
1693	Factor IXa inhibitor	9	0.9999
1694	Factor VII inhibitor	134	0.9956
1695	Factor VIIa inhibitor	214	0.9852
1696	Factor Xa inhibitor	1741	0.9929
1697	Factor XIa inhibitor	6	0.9427
1698	Factor XIIIa inhibitor	52	0.9830
1699	Factor XIIIa stimulant	3	0.9976
1700	FAD diphosphatase inhibitor	17	0.9930
1701	Falcipain 2 inhibitor	112	0.9758
1702	Falcipain 3 inhibitor	14	0.8963
1703	Falcipain inhibitor	112	0.9758
1704	Farnesoid X receptor agonist	96	0.9947
1705	Farnesoid X receptor antagonist	22	0.8842
1706	Farnesyltransferase inhibitor	2518	0.9877
1707	Farnesyltranstransferase inhibitor	5	0.9816
1708	Fas antagonist	5	1.0000
1709	Fasciculation	28	0.8701
1710	Fatty acid elongase inhibitor	18	0.9800
1711	Fatty acid oxidation inhibitor	45	0.9943
1712	Fatty acid synthase inhibitor	46	0.9891
1713	Fatty liver	42	0.8053
1714	Fatty-acyl-CoA synthase inhibitor	5	0.9353
1715	Fatty-acyl-ethyl-ester synthase inhibitor	3	0.9977
1716	Female sexual dysfunction treatment	127	0.9712
1717	Ferredoxin hydrogenase inhibitor	8	0.9573
1718	Ferredoxin-NAD+ reductase inhibitor	3	0.9674
1719	Ferredoxin-NADP+ reductase inhibitor	6	0.9780
1720	Ferredoxin-nitrite reductase inhibitor	12	0.9559
1721	Ferrochelatase inhibitor	5	0.9896
1722	Feruloyl esterase inhibitor	6	0.9208
1723	Fibrillation, atrial	16	0.8309
1724	Fibrinogen receptor antagonist	29	0.8844
1725	Fibrinolytic	38	0.8303
1726	Fibroblast activation protein alpha inhibitor	36	0.9995
1727	Fibroblast growth factor 1 agonist	3	0.9585
1728	Fibroblast growth factor 1 antagonist	579	0.9787
1729	Fibroblast growth factor 2 antagonist	143	0.9572
1730	Fibroblast growth factor 3 antagonist	177	0.9676
1731	Fibroblast growth factor agonist	4	0.9270
1732	Fibroblast growth factor antagonist	785	0.9756
1733	Fibrolase inhibitor	4	0.8907
1734	Fibromyalgia syndrome treatment	53	0.9362
1735	Fibrosis treatment	95	0.9545
1736	Fibrosis, interstitial	8	0.8614
1737	Flavin-containing monooxygenase inhibitor	9	0.9471
1738	Flavin-containing monooxygenase substrate	65	0.8973
1739	FMN adenylyltransferase inhibitor	7	0.9999
1740	FMN reductase inhibitor	22	0.9507
1741	FMO1 substrate	17	0.9050
1742	FMO3 substrate	38	0.8916
1743	Focal adhesion kinase 1 inhibitor	38	0.9501
1744	Focal adhesion kinase 2 inhibitor	140	0.9157
1745	Focal adhesion kinase inhibitor	202	0.9195
1746	Folate antagonist	21	0.8698
1747	Folate transporter 1 inhibitor	5	0.9997
1748	Follicle-stimulating hormone agonist	11	0.9469
1749	Follicle-stimulating hormone antagonist	54	0.9997
1750	Folylpolyglutamate synthase inhibitor	19	0.9998
1751	Formaldehyde dehydrogenase (glutathione) inhibitor	17	0.9769
1752	Formaldehyde dehydrogenase inhibitor	14	0.9871
1753	Formaldehyde transketolase inhibitor	6	0.9203
1754	Formate C-acetyltransferase inhibitor	5	0.9978
1755	Formate dehydrogenase inhibitor	21	0.9778
1756	Formate-dihydrofolate ligase inhibitor	14	0.8918
1757	Formimidoylglutamase inhibitor	3	0.9989
1758	Formimidoyltetrahydrofolate cyclodeaminase inhibitor	8	0.9914
1759	Formyl peptide receptor antagonist	58	0.9997
1760	Formyltetrahydrofolate dehydrogenase inhibitor	6	0.9917
1761	Fragilysin inhibitor	6	0.8580
1762	Free fatty acid receptor 1 agonist	28	0.9997
1763	Free radical scavenger	249	0.9392
1764	Fructan beta-fructosidase inhibitor	4	0.9647
1765	Fructokinase inhibitor	13	0.9969
1766	Fructose 5-dehydrogenase (NADP+) inhibitor	3	0.9899
1767	Fructose 5-dehydrogenase inhibitor	4	0.8004
1768	Fructose-1,6-bisphosphatase inhibitor	211	0.9989
1769	Fructose-2,6-bisphosphate 2-phosphatase inhibitor	12	0.9637
1770	Fructose-2,6-bisphosphate 6-phosphatase inhibitor	4	0.9967
1771	Fructuronate reductase inhibitor	3	0.9946
1772	FtsZ polymerization inhibitor	5	0.9998
1773	Fucokinase inhibitor	9	0.9965
1774	Fucosterol-epoxide lyase inhibitor	9	0.9326
1775	Fumarate hydratase inhibitor	24	0.9958
1776	Fumarate reductase (NADH) inhibitor	7	0.8936
1777	Fumarylacetoacetase inhibitor	14	0.9945
1778	Furin inhibitor	23	0.9824
1779	Fusarinine-C ornithinesterase inhibitor	3	0.8407
1780	G protein-coupled receptor agonist	73	0.9935
1781	GABA A inverse agonist	8	0.8922
1782	GABA A receptor agonist	231	0.9451
1783	GABA A receptor antagonist	2765	0.9873
1784	GABA aminotransferase inhibitor	14	0.8532
1785	GABA B receptor agonist	10	0.9188
1786	GABA B receptor antagonist	63	0.9940
1787	GABA C receptor agonist	3	0.9867
1788	GABA C receptor antagonist	24	0.9716
1789	GABA inverse agonist	8	0.8922
1790	GABA receptor agonist	386	0.9337
1791	GABA receptor antagonist	2835	0.9870
1792	GABA transporter 1 inhibitor	150	0.9956
1793	GABA transporter 2 inhibitor	11	0.9893
1794	GABA transporter 3 inhibitor	8	0.9900
1795	GABA transporter inhibitor	157	0.9938
1796	GABA uptake inhibitor	68	0.9934
1797	Galactokinase inhibitor	6	0.9818
1798	Galactolipase inhibitor	12	0.8999
1799	Galactorrhea	12	0.8594
1800	Galactose 1-dehydrogenase (NADP+) inhibitor	3	0.9893
1801	Galactose oxidase inhibitor	13	0.9774
1802	Galactoside 2-alpha-L-fucosyltransferase inhibitor	12	0.9856
1803	Galactoside O-acetyltransferase inhibitor	4	0.9761
1804	Galactosylceramidase inhibitor	8	0.9847
1805	Galactosylceramide sulfotransferase inhibitor	10	0.9750
1806	Galactosylgalactosylglucosylceramidase inhibitor	5	0.9956
1807	Galacturan 1,4-alpha-galacturonidase inhibitor	4	0.9915
1808	Galectin 3 antagonist	4	0.9989
1809	Gallate decarboxylase inhibitor	5	0.9813
1810	Gametolysin inhibitor	15	0.9271
1811	Gamma-butyrobetaine dioxygenase inhibitor	18	0.9188
1812	Gamma-D-Glutamyl-meso-diaminopimelate peptidase inhibitor	3	0.9820
1813	Gamma-glutamyl hydrolase inhibitor	42	0.9932
1814	Gamma-glutamyltransferase inhibitor	28	0.9128
1815	Gamma-guanidinobutyraldehyde dehydrogenase inhibitor	5	0.8899
1816	Ganglioside galactosyltransferase inhibitor	9	0.9696
1817	Gastric antisecretory	489	0.9209
1818	Gastric emptying disorders treatment	99	0.9614
1819	Gastric emptying impairment	3	0.9992
1820	Gastricsin inhibitor	25	0.9800
1821	Gastrin inhibitor	81	0.8352
1822	Gastrin-releasing peptide antagonist	50	0.9652
1823	Gastritis treatment	14	0.9225
1824	Gastroesophageal reflux disease treatment	220	0.9645
1825	Gastrointestinal disorders treatment	294	0.9427
1826	Gastrointestinal disturbance	176	0.8472
1827	Gastrointestinal hemorrhage	13	0.8250
1828	Gastrointestinal motility stimulant	79	0.9267
1829	Gaucher disease treatment	12	0.9744
1830	GDP-L-fucose synthase inhibitor	3	0.9991
1831	GDP-mannose 4,6-dehydratase inhibitor	8	0.9997
1832	GDP-mannose 6-dehydrogenase inhibitor	6	0.8995
1833	Gelatinase inhibitor	18	0.9729
1834	General pump inhibitor	40	0.8093
1835	Genotoxic	146	0.9488
1836	Gentamicin 2''-nucleotidyltransferase inhibitor	4	0.9968
1837	Gentamicin 3'-N-acetyltransferase inhibitor	12	0.9980
1838	Gentisate 1,2-dioxygenase inhibitor	6	0.9880
1839	Geranylgeranyl-diphosphate geranylgeranyltransferase inhibitor	9	0.9614
1840	Geranylgeranyltransferase I inhibitor	668	0.9951
1841	Geranylgeranyltransferase inhibitor	735	0.9944
1842	Geranyltranstransferase (Leishmania) inhibitor	27	0.9999
1843	Geranyltranstransferase inhibitor	105	0.9948
1844	Gestagen antagonist	7	0.9596
1845	Gestagen-like	56	0.9992
1846	GHS receptor agonist	25	0.9895
1847	GHS receptor antagonist	134	0.9969
1848	Giant cell myocarditis	3	0.9967
1849	Gingipain K inhibitor	6	0.9404
1850	Gingipain R inhibitor	7	0.9869
1851	Glaucoma	86	0.8410
1852	Globoside alpha-N-acetylgalactosaminyltransferase inhibitor	13	0.9641
1853	Glucagon receptor antagonist	362	0.9936
1854	Glucagon-like peptide 1 agonist	9	0.9362
1855	Glucagon-like peptide 1 receptor antagonist	30	0.9986
1856	Glucan 1,3-alpha-glucosidase inhibitor	19	0.9932
1857	Glucan 1,3-beta-glucosidase inhibitor	9	0.9913
1858	Glucan 1,4-alpha-glucosidase inhibitor	20	0.9964
1859	Glucan 1,4-alpha-maltotetraohydrolase inhibitor	3	0.9778
1860	Glucan 1,4-alpha-maltotriohydrolase inhibitor	3	0.9617
1861	Glucan 1,4-beta-glucosidase inhibitor	9	0.9804
1862	Glucan 1,6-alpha-glucosidase inhibitor	6	0.9888
1863	Glucan endo-1,3-alpha-glucosidase inhibitor	3	0.9958
1864	Glucan endo-1,3-beta-D-glucosidase inhibitor	11	0.8889
1865	Glucan endo-1,6-beta-glucosidase inhibitor	7	0.9140
1866	Glucarate dehydratase inhibitor	5	0.9909
1867	Glucocorticoid agonist	307	0.9936
1868	Glucocorticoid antagonist	900	0.9944
1869	Gluconate 2-dehydrogenase (acceptor) inhibitor	4	0.8010
1870	Gluconate 5-dehydrogenase inhibitor	3	0.9570
1871	Gluconate dehydratase inhibitor	4	0.9948
1872	Gluconokinase inhibitor	3	0.9731
1873	Gluconolactonase inhibitor	3	0.9788
1874	Glucosamine 6-phosphate N-acetyltransferase inhibitor	6	0.9958
1875	Glucosamine N-acetyltransferase inhibitor	6	0.9971
1876	Glucosamine-1-phosphate N-acetyltransferase inhibitor	4	0.9940
1877	Glucosamine-6-phosphate deaminase inhibitor	12	0.9826
1878	Glucose 1-dehydrogenase inhibitor	8	0.9855
1879	Glucose oxidase inhibitor	7	0.8550
1880	Glucose-1,6-bisphosphate synthase inhibitor	11	0.9975
1881	Glucose-1-phosphatase inhibitor	3	0.9917
1882	Glucose-1-phosphate adenylyltransferase inhibitor	15	0.9958
1883	Glucose-1-phosphate cytidylyltransferase inhibitor	12	0.9999
1884	Glucose-6-phosphate isomerase inhibitor	22	0.9986
1885	Glucose-6-phosphate translocase inhibitor	25	0.9975
1886	Glucose-dependent insulinotropic receptor agonist	62	0.9986
1887	Glucosyl transferase inhibitor	36	0.9478
1888	Glucosylceramidase inhibitor	48	0.9962
1889	Glucuronate isomerase inhibitor	5	0.9805
1890	Glucuronolactone reductase inhibitor	3	0.9890
1891	Glutamate (mGluR group I) agonist	30	0.9679
1892	Glutamate (mGluR group I) antagonist	565	0.9793
1893	Glutamate (mGluR group II) agonist	36	0.9899
1894	Glutamate (mGluR group II) antagonist	273	0.9994
1895	Glutamate (mGluR group III) agonist	13	0.9993
1896	Glutamate (mGluR group III) antagonist	77	0.9798
1897	Glutamate (mGluR) agonist	83	0.9876
1898	Glutamate (mGluR) antagonist	858	0.9866
1899	Glutamate (mGluR1) agonist	10	0.9983
1900	Glutamate (mGluR1) antagonist	255	0.9774
1901	Glutamate (mGluR1a) agonist	4	0.9999
1902	Glutamate (mGluR2) agonist	30	0.9981
1903	Glutamate (mGluR2) antagonist	197	0.9989
1904	Glutamate (mGluR3) agonist	11	0.9953
1905	Glutamate (mGluR3) antagonist	154	0.9991
1906	Glutamate (mGluR4) agonist	5	0.9927
1907	Glutamate (mGluR4) antagonist	29	0.9977
1908	Glutamate (mGluR5) agonist	17	0.9460
1909	Glutamate (mGluR5) antagonist	410	0.9830
1910	Glutamate (mGluR5a) agonist	4	0.9999
1911	Glutamate (mGluR6) agonist	8	0.9991
1912	Glutamate (mGluR6) antagonist	25	0.9707
1913	Glutamate (mGluR8) agonist	3	0.9977
1914	Glutamate (mGluR8) antagonist	42	0.9817
1915	Glutamate 5-kinase inhibitor	9	0.8882
1916	Glutamate carboxypeptidase inhibitor	21	0.9901
1917	Glutamate decarboxylase inhibitor	43	0.9734
1918	Glutamate dehydrogenase (NADP+) inhibitor	18	0.9917
1919	Glutamate dehydrogenase [NAD(P)+] inhibitor	45	0.9882
1920	Glutamate dehydrogenase inhibitor	34	0.9595
1921	Glutamate formimidoyltransferase inhibitor	11	0.9969
1922	Glutamate N-acetyltransferase inhibitor	4	0.9913
1923	Glutamate racemase inhibitor	72	0.9968
1924	Glutamate receptor agonist	370	0.9800
1925	Glutamate receptor antagonist	6051	0.9730
1926	Glutamate release inhibitor	58	0.9520
1927	Glutamate synthase (ferredoxin) inhibitor	21	0.9554
1928	Glutamate synthase (NADPH) inhibitor	54	0.9772
1929	Glutamate uptake inhibitor	9	0.9990
1930	Glutamate-1-semialdehyde 2,1-aminomutase inhibitor	9	0.9571
1931	Glutamate-5-semialdehyde dehydrogenase inhibitor	4	0.8871
1932	Glutamate-cysteine ligase inhibitor	36	0.9917
1933	Glutamate-tRNA ligase inhibitor	6	0.8257
1934	Glutamin-(asparagin-)ase inhibitor	13	0.9659
1935	Glutaminase inhibitor	20	0.9500
1936	Glutamine synthetase inhibitor	38	0.9652
1937	Glutamine-fructose-6-phosphate transaminase inhibitor	4	0.9942
1938	Glutamine-phenylpyruvate transaminase inhibitor	3	0.9666
1939	Glutamine-pyruvate transaminase inhibitor	7	0.9931
1940	Glutamine-tRNA ligase inhibitor	9	0.9891
1941	Glutaminyl-peptide cyclotransferase inhibitor	12	0.8868
1942	Glutaminyl-tRNA synthase (glutamine-hydrolysing) inhibitor	4	0.9947
1943	Glutamyl endopeptidase II inhibitor	3	0.8403
1944	Glutarate-semialdehyde dehydrogenase inhibitor	3	0.9824
1945	Glutaryl-CoA dehydrogenase inhibitor	5	0.9875
1946	Glutathione dehydrogenase (ascorbate) inhibitor	7	0.9572
1947	Glutathione peroxidase inhibitor	10	0.9461
1948	Glutathione reductase (NADPH) stimulant	11	0.9752
1949	Glutathione reductase inhibitor	46	0.9495
1950	Glutathione reductase stimulant	11	0.9752
1951	Glutathione S-transferase inhibitor	53	0.9728
1952	Glutathione S-transferase substrate	218	0.9635
1953	Glutathione synthase inhibitor	15	0.9827
1954	Glutathione thiolesterase inhibitor	3	0.9455
1955	Glutathione-disulfide reductase inhibitor	46	0.9852
1956	Glutathionylspermidine synthase inhibitor	17	0.9997
1957	Glyceraldehyde-3-phosphate dehydrogenase (NADP+) inhibitor	12	0.9616
1958	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitor	16	0.9858
1959	Glyceraldehyde-3-phosphate dehydrogenase inhibitor	23	0.9845
1960	Glycerate kinase inhibitor	12	0.9991
1961	Glycerol 2-dehydrogenase (NADP+) inhibitor	4	0.9763
1962	Glycerol dehydratase inhibitor	6	0.9951
1963	Glycerol dehydrogenase (NADP+) inhibitor	5	0.9770
1964	Glycerol dehydrogenase inhibitor	34	0.9854
1965	Glycerol kinase inhibitor	18	0.9934
1966	Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase inhibitor	7	0.9991
1967	Glycerol-1-phosphatase inhibitor	3	0.9922
1968	Glycerol-3-phosphate dehydrogenase (NAD+) inhibitor	21	0.9806
1969	Glycerol-3-phosphate dehydrogenase [NAD(P)+] inhibitor	6	0.9989
1970	Glycerol-3-phosphate dehydrogenase inhibitor	28	0.9068
1971	Glycerol-3-phosphate O-acyltransferase inhibitor	23	0.9482
1972	Glycerol-3-phosphate oxidase inhibitor	6	0.8267
1973	Glycerone-phosphate O-acyltransferase inhibitor	10	0.9846
1974	Glycerophosphocholine cholinephosphodiesterase inhibitor	6	0.9942
1975	Glycerophosphocholine phosphodiesterase inhibitor	8	0.9962
1976	Glyceryl-ether monooxygenase inhibitor	11	0.8711
1977	Glycine amidinotransferase inhibitor	5	0.9552
1978	Glycine C-acetyltransferase inhibitor	12	0.9078
1979	Glycine dehydrogenase (decarboxylating) inhibitor	3	0.9860
1980	Glycine hydroxymethyltransferase inhibitor	30	0.9649
1981	Glycine N-acyltransferase inhibitor	6	0.9912
1982	Glycine N-benzoyltransferase inhibitor	6	0.9901
1983	Glycine N-choloyltransferase inhibitor	10	0.9943
1984	Glycine N-methyltransferase inhibitor	9	0.9940
1985	Glycine receptor agonist	13	0.9401
1986	Glycine receptor antagonist	77	0.9671
1987	Glycine transaminase inhibitor	7	0.9937
1988	Glycine transporter 1 inhibitor	466	0.9968
1989	Glycine transporter 2 inhibitor	74	0.9842
1990	Glycine transporter inhibitor	550	0.9922
1991	Glycine-tRNA ligase inhibitor	10	0.9072
1992	Glycogen (starch) synthase inhibitor	26	0.9452
1993	Glycogen synthase kinase-3 alpha inhibitor	345	0.9894
1994	Glycogen synthase kinase-3 beta inhibitor	882	0.9815
1995	Glycogen synthase kinase-3 inhibitor	1215	0.9817
1996	Glycogen synthase stimulant	9	0.8707
1997	Glycogenin glucosyltransferase inhibitor	8	0.9974
1998	Glycolaldehyde dehydrogenase inhibitor	6	0.9940
1999	Glycolate dehydrogenase inhibitor	3	0.9747
2000	Glycolipid 2-alpha-mannosyltransferase inhibitor	9	0.9978
2001	Glycolipid 3-alpha-mannosyltransferase inhibitor	12	0.9973
2002	Glycopeptide alpha-N-acetylgalactosaminidase inhibitor	8	0.9863
2003	Glycoprotein 3-alpha-L-fucosyltransferase inhibitor	10	0.9770
2004	Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase inhibitor	9	0.9565
2005	Glycosylceramidase inhibitor	14	0.9928
2006	Glycosylphosphatidylinositol diacylglycerol-lyase inhibitor	17	0.9730
2007	Glycosylphosphatidylinositol phospholipase D inhibitor	4	0.8797
2008	Glyoxylate oxidase inhibitor	3	0.9771
2009	Glyoxylate reductase (NADP+) inhibitor	12	0.9294
2010	Glyoxylate reductase inhibitor	4	0.9231
2011	Gly-X carboxypeptidase inhibitor	6	0.9863
2012	GMP reductase inhibitor	17	0.9968
2013	GMP synthase inhibitor	57	0.9848
2014	Gonadotropin antagonist	24	0.8662
2015	Gout treatment	117	0.9402
2016	GP IIb/IIIa receptor antagonist	2068	0.9911
2017	G-protein-coupled bile acid receptor 1 agonist	9	0.9605
2018	G-protein-coupled receptor 120 agonist	10	0.9999
2019	G-protein-coupled receptor kinase inhibitor	22	0.8262
2020	Granulocyte macrophage colony stimulating factor agonist	12	0.9743
2021	Granulocyte stimulating factor agonist	30	1.0000
2022	Granzyme A inhibitor	9	0.9766
2023	Granzyme B inhibitor	23	0.9691
2024	Growth factor agonist	244	0.9172
2025	Growth factor antagonist	3528	0.9682
2026	Growth factor receptor-bound protein 2 antagonist	72	0.9999
2027	Growth hormone agonist	10	0.9527
2028	Growth hormone release inhibitor	69	0.9828
2029	Growth hormone release promoting	58	0.9829
2030	Growth hormone releasing factor agonist	445	0.9959
2031	Growth hormone releasing factor antagonist	38	0.9997
2032	Growth stimulant	61	0.9387
2033	GRP78 expression inhibitor	5	0.9999
2034	GST A substrate	12	0.9043
2035	GST M substrate	13	0.9248
2036	GST M1-1 substrate	8	0.9101
2037	GST P substrate	15	0.9555
2038	GST P1-1 substrate	14	0.9580
2039	GST T substrate	8	0.9507
2040	GST T1-1 substrate	8	0.9507
2041	GTP cyclohydrolase I inhibitor	15	0.9939
2042	GTP cyclohydrolase IIa inhibitor	6	0.9999
2043	Guanidinoacetase inhibitor	6	0.9805
2044	Guanidinoacetate kinase inhibitor	12	0.9093
2045	Guanidinoacetate N-methyltransferase inhibitor	6	0.9809
2046	Guanidinobutyrase inhibitor	13	0.9925
2047	Guanidinodeoxy-scyllo-inositol-4-phosphatase inhibitor	3	0.9938
2048	Guanidinopropionase inhibitor	5	0.9950
2049	Guanine deaminase inhibitor	13	0.9830
2050	Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase inhibitor	4	0.9204
2051	Guanylate cyclase 1 inhibitor	8	1.0000
2052	Guanylate cyclase 1 stimulant	10	0.9309
2053	Guanylate cyclase inhibitor	96	0.9622
2054	Guanylate cyclase stimulant	74	0.9571
2055	Guanylate kinase inhibitor	15	0.9913
2056	Gynecological disorders treatment	679	0.9743
2057	H+/K+-transporting ATPase inhibitor	601	0.9795
2058	H+-exporting ATPase inhibitor	12	0.9271
2059	H+-transporting two-sector ATPase inhibitor	6	0.9083
2060	Hair growth stimulant	508	0.9671
2061	Haloacetate dehalogenase inhibitor	3	0.9948
2062	Haloalkane dehalogenase inhibitor	4	0.9979
2063	HCV IRES inhibitor	9	0.8681
2064	HCV NS3/NS4A protease inhibitor	617	0.9842
2065	HCV NS3-helicase inhibitor	86	0.9688
2066	HCV NS5A inhibitor	20	0.9999
2067	HCV NS5B polymerase inhibitor	524	0.9948
2068	HDL-cholesterol increasing	175	0.9532
2069	Headache	838	0.8131
2070	Heart failure treatment	1565	0.9462
2071	Heat shock protein 27 antagonist	9	0.8160
2072	Heat shock protein 70 agonist	24	0.9444
2073	Heat shock protein 70 antagonist	23	0.9637
2074	Heat shock protein 90 antagonist	332	0.9756
2075	Heat shock protein agonist	25	0.9204
2076	Heat shock protein antagonist	364	0.9702
2077	Hedgehog signaling activator	4	1.0000
2078	Hedgehog signaling inhibitor	83	0.9708
2079	Helicase E1 (Human papillomavirus) inhibitor	28	0.9998
2080	Hematemesis	7	0.8318
2081	Hematinic	13	0.9337
2082	Hematopoietic	68	0.8997
2083	Hematopoietic inhibitor	18	0.9108
2084	Hematotoxic	1142	0.8266
2085	Hematuria	43	0.8519
2086	Heme oxygenase inhibitor	7	0.8033
2087	Heme oxygenase stimulant	10	0.9861
2088	Hemostatic	101	0.8983
2089	Heparan-alpha-glucosaminide N-acetyltransferase inhibitor	12	0.9861
2090	Heparanase inhibitor	60	0.9845
2091	Heparin epidermal growth factor antagonist	114	0.9996
2092	Hepatic disorders treatment	706	0.8964
2093	Hepatitis	397	0.7976
2094	Hepatocyte growth factor agonist	7	0.8722
2095	Hepatocyte growth factor antagonist	526	0.9773
2096	Hepatocyte nuclear factor 4 alpha agonist	6	0.9996
2097	Hepatocyte nuclear factor 4 alpha antagonist	6	0.9208
2098	Hepatocyte nuclear factor agonist	6	0.9996
2099	Hepatocyte nuclear factor antagonist	6	0.9208
2100	Hepatoprotectant	291	0.9033
2101	Hepatotoxic	1033	0.8370
2102	HERG 1 channel blocker	38	0.9411
2103	HERG channel blocker	1207	0.9520
2104	Hexokinase inhibitor	193	0.9557
2105	Hexokinase stimulant	119	0.9911
2106	HIF1A expression inhibitor	23	0.8290
2107	High-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase inhibitor	3	0.9983
2108	Hippurate hydrolase inhibitor	4	0.9922
2109	Hirsutism treatment	82	0.9846
2110	Histamine agonist	118	0.9367
2111	Histamine antagonist	2720	0.9636
2112	Histamine H1 receptor agonist	5	0.9848
2113	Histamine H1 receptor antagonist	858	0.9771
2114	Histamine H2 receptor agonist	36	0.9789
2115	Histamine H2 receptor antagonist	375	0.9819
2116	Histamine H3 receptor agonist	55	0.9994
2117	Histamine H3 receptor antagonist	1447	0.9944
2118	Histamine H4 receptor antagonist	131	0.9955
2119	Histamine N-methyltransferase inhibitor	69	0.9807
2120	Histamine release inhibitor	118	0.8600
2121	Histamine release stimulant	21	0.8929
2122	Histidine ammonia-lyase inhibitor	34	0.9844
2123	Histidine decarboxylase inhibitor	33	0.9802
2124	Histidine kinase inhibitor	4	0.9246
2125	Histidine N-acetyltransferase inhibitor	6	0.8181
2126	Histidine-tRNA ligase inhibitor	19	0.9940
2127	Histidinol dehydrogenase inhibitor	21	0.9347
2128	Histidinol-phosphatase inhibitor	6	0.9731
2129	Histone acetylation inducer	9	1.0000
2130	Histone acetyltransferase inhibitor	43	0.9182
2131	Histone deacetylase 1 inhibitor	887	0.9954
2132	Histone deacetylase 1A inhibitor	8	0.9996
2133	Histone deacetylase 1B inhibitor	36	0.9999
2134	Histone deacetylase 2 inhibitor	523	0.9946
2135	Histone deacetylase 3 inhibitor	533	0.9931
2136	Histone deacetylase 4 inhibitor	487	0.9939
2137	Histone deacetylase 6 inhibitor	719	0.9969
2138	Histone deacetylase 8 inhibitor	312	0.9915
2139	Histone deacetylase class I inhibitor	1133	0.9951
2140	Histone deacetylase class II inhibitor	811	0.9957
2141	Histone deacetylase class IIa inhibitor	497	0.9940
2142	Histone deacetylase class IIb inhibitor	726	0.9969
2143	Histone deacetylase class III inhibitor	56	0.9653
2144	Histone deacetylase inhibitor	1924	0.9887
2145	Histone deacetylase SIRT1 inhibitor	38	0.9562
2146	Histone deacetylase SIRT1 stimulant	63	0.9942
2147	Histone deacetylase SIRT2 inhibitor	42	0.9706
2148	Histone deacetylase SIRT2 stimulant	5	0.9989
2149	Histone deacetylase stimulant	63	0.9942
2150	Histone-arginine N-methyltransferase inhibitor	9	0.9941
2151	Histone-lysine N-methyltransferase inhibitor	17	0.9992
2152	HIV attachment inhibitor	13	0.8900
2153	HIV fusion inhibitor	4	1.0000
2154	HIV-1 integrase (3'-Processing) inhibitor	358	0.9845
2155	HIV-1 integrase (Overall Integration) inhibitor	55	0.9774
2156	HIV-1 integrase (Strand Transfer) inhibitor	355	0.9860
2157	HIV-1 integrase inhibitor	884	0.9793
2158	HIV-1 protease inhibitor	2615	0.9913
2159	HIV-1 reverse transcriptase inhibitor	2106	0.9879
2160	HIV-2 retropepsin inhibitor	16	0.9990
2161	HIV-2 reverse transcriptase inhibitor	3	0.9851
2162	HLA-A2 antigen antagonist	188	0.9992
2163	HMG CoA reductase inhibitor	484	0.9918
2164	HMG CoA synthase inhibitor	5	0.9801
2165	HMGCS2 expression enhancer	5	0.9198
2166	HMOX1 expression enhancer	69	0.9033
2167	Homoaconitate hydratase inhibitor	3	0.9894
2168	Homocitrate synthase inhibitor	18	0.9821
2169	Homocysteine desulfhydrase inhibitor	8	0.9901
2170	Homocysteine S-methyltransferase inhibitor	4	0.9948
2171	Homogentisate 1,2-dioxygenase inhibitor	12	0.9552
2172	Homoisocitrate dehydrogenase inhibitor	3	0.9999
2173	Homoserine dehydrogenase inhibitor	14	0.8914
2174	Homoserine kinase inhibitor	24	0.9844
2175	Homoserine O-acetyltransferase inhibitor	11	0.9977
2176	Homoserine O-succinyltransferase inhibitor	3	0.9977
2177	Homospermidine synthase inhibitor	4	0.9949
2178	Horrilysin inhibitor	3	0.9846
2179	Hot flush treatment	91	0.9840
2180	Huntington's disease treatment	143	0.9511
2181	Hyaluronic acid agonist	3	0.9246
2182	Hydrogen dehydrogenase inhibitor	3	0.8996
2183	Hydroperoxide dehydratase inhibitor	12	0.9904
2184	Hydroxyacylglutathione hydrolase inhibitor	55	0.9754
2185	Hydroxylamine oxidase inhibitor	6	0.9056
2186	Hydroxylamine reductase (NADH) inhibitor	18	0.8748
2187	Hydroxylamine reductase inhibitor	6	0.8633
2188	Hydroxylysine kinase inhibitor	9	0.9973
2189	Hydroxymethylbilane synthase inhibitor	11	0.9606
2190	Hydroxymethylglutaryl-CoA lyase inhibitor	7	0.9534
2191	Hydroxymethylglutaryl-CoA reductase inhibitor	5	0.9953
2192	Hydroxypyruvate reductase inhibitor	17	0.9964
2193	Hydroxyquinol 1,2-dioxygenase inhibitor	9	0.9970
2194	Hydroxysteroid dehydrogenase inhibitor	4	0.9365
2195	Hypercalcaemic	19	0.8470
2196	Hypercalcemia treatment	43	0.9584
2197	Hypercholesterolemic	10	0.8511
2198	Hyperglycemic	71	0.8011
2199	Hyperparathyroidism treatment	68	0.9845
2200	Hyperprolactinemia treatment	9	0.9760
2201	Hypertensive	736	0.8149
2202	Hypertensive, ophthalmic	10	0.9578
2203	Hyperthermic	263	0.8439
2204	Hyperuricemia	4	0.9471
2205	Hypnotic	715	0.9230
2206	Hypocalcaemic	29	0.8539
2207	Hypoglycemic	413	0.9188
2208	Hypogonadism treatment	125	0.9988
2209	Hypolipemic	2014	0.8916
2210	Hypomagnesemia	3	0.9376
2211	Hypomania	22	0.9436
2212	Hyponitrite reductase inhibitor	3	0.9781
2213	Hypotension	1053	0.8323
2214	Hypothermic	295	0.8441
2215	Hypotonia	98	0.8001
2216	Hypoxanthine phosphoribosyltransferase inhibitor	37	0.9896
2217	Hypoxia inducible factor 1 alpha inhibitor	60	0.9438
2218	I kappa B kinase 2 inhibitor	310	0.9732
2219	I kappa B kinase inhibitor	387	0.9653
2220	I(Ks) voltage-gated potassium channel blocker	38	0.9996
2221	ICAM 1 antagonist	389	0.9955
2222	ICAM1 expression inhibitor	58	0.8807
2223	Iduronate-2-sulfatase inhibitor	3	0.9951
2224	IgA-specific metalloendopeptidase inhibitor	9	0.9751
2225	IgA-specific serine endopeptidase inhibitor	5	0.9531
2226	Ileal bile acid transport inhibitor	144	0.9983
2227	Imidazoleacetate 4-monooxygenase inhibitor	13	0.9896
2228	Imidazoleglycerol-phosphate dehydratase inhibitor	5	0.9981
2229	Imidazoline I1 receptor agonist	3	0.9786
2230	Imidazoline I1 receptor antagonist	52	0.9996
2231	Imidazoline I2 receptor antagonist	140	0.9997
2232	Imidazoline receptor agonist	6	0.9715
2233	Imidazoline receptor antagonist	158	0.9994
2234	Immunoglobulin E antagonist	39	0.9417
2235	Immunoglobulin Fc receptor antagonist	36	0.9467
2236	Immunomodulator	1484	0.8917
2237	Immunostimulant	675	0.9063
2238	Immunosuppressant	2090	0.8710
2239	IMP cyclohydrolase inhibitor	10	0.9998
2240	Indanol dehydrogenase inhibitor	13	0.9249
2241	Indole-3-acetaldehyde reductase (NADPH) inhibitor	11	0.9927
2242	Indoleacetaldoxime dehydratase inhibitor	12	0.9226
2243	Indoleamine-pyrrole 2,3-dioxygenase inhibitor	131	0.9825
2244	Indolepyruvate C-methyltransferase inhibitor	4	0.9738
2245	Inducible nitric-oxide synthase inhibitor	441	0.9769
2246	Inflammation	442	0.8062
2247	Inflammatory Bowel disease treatment	1272	0.8906
2248	Inorganic diphosphatase inhibitor	28	0.9560
2249	Inosine kinase inhibitor	4	0.9999
2250	Inosine monophosphate dehydrogenase 1 inhibitor	69	0.9992
2251	Inosine monophosphate dehydrogenase 2 inhibitor	346	0.9997
2252	Inosine monophosphate dehydrogenase inhibitor	452	0.9977
2253	Inosine nucleosidase inhibitor	4	0.9908
2254	Inosine-adenosine-guanosine-nucleoside hydrolase inhibitor	4	1.0000
2255	Inositol 1,4,5-triphosphate receptor 1 antagonist	10	1.0000
2256	Inositol 1,4,5-triphosphate receptor antagonist	12	0.9628
2257	Inositol 1,4,5-trisphosphate 3-kinase B inhibitor	11	0.9865
2258	Inositol 1,4,5-trisphosphate 3-kinase inhibitor	15	0.9489
2259	Inositol oxygenase inhibitor	34	0.9533
2260	Inositol polyphosphate-5-phosphatase D stimulant	7	0.9998
2261	Inositol-3-phosphate synthase inhibitor	20	0.9923
2262	Inositol-polyphosphate 5-phosphatase inhibitor	19	0.9851
2263	Inotropic	36	0.8742
2264	Insecticide	193	0.9607
2265	Insulin antagonist	339	0.9672
2266	Insulin growth factor antagonist	532	0.9838
2267	Insulin like growth factor 1 antagonist	488	0.9810
2268	Insulin like growth factor 3 antagonist	44	1.0000
2269	Insulin promoter	43	0.8291
2270	Insulin secretagoues	249	0.9593
2271	Insulin sensitizer	224	0.9684
2272	Insulysin inhibitor	49	0.8563
2273	Integrin alpha1beta1 antagonist	42	0.9940
2274	Integrin alpha2 antagonist	35	0.9825
2275	Integrin alpha2beta1 antagonist	25	0.9788
2276	Integrin alpha4 antagonist	2146	0.9979
2277	Integrin alpha4beta1 antagonist	941	0.9968
2278	Integrin alpha4beta7 antagonist	602	0.9978
2279	Integrin alpha5beta1 antagonist	163	0.9910
2280	Integrin alpha5beta6 antagonist	14	0.9999
2281	Integrin alphaLbeta2 antagonist	38	0.9996
2282	Integrin alphaVbeta1 antagonist	17	0.9555
2283	Integrin alphaVbeta3 antagonist	14	0.9885
2284	Integrin alphaVbeta5 antagonist	307	0.9984
2285	Integrin alphaVbeta6 antagonist	79	0.9985
2286	Integrin antagonist	4042	0.9917
2287	Integrin-linked kinase inhibitor	13	1.0000
2288	Interferon agonist	134	0.9651
2289	Interferon alpha agonist	4	0.9562
2290	Interferon antagonist	85	0.9555
2291	Interferon gamma antagonist	84	0.9595
2292	Interferon inducer	112	0.9839
2293	Interleukin 1 antagonist	919	0.9527
2294	Interleukin 1 beta converting enzyme inhibitor	289	0.9895
2295	Interleukin 10 agonist	37	0.9074
2296	Interleukin 10 antagonist	6	0.9666
2297	Interleukin 12 agonist	130	0.9624
2298	Interleukin 1a antagonist	17	0.9378
2299	Interleukin 1b antagonist	499	0.9681
2300	Interleukin 2 agonist	15	0.8700
2301	Interleukin 2 antagonist	228	0.9545
2302	Interleukin 4 antagonist	146	0.9512
2303	Interleukin 5 antagonist	131	0.9621
2304	Interleukin 6 antagonist	214	0.9260
2305	Interleukin 8 antagonist	209	0.9507
2306	Interleukin agonist	177	0.9374
2307	Interleukin antagonist	1566	0.9291
2308	Intermittent claudication treatment	17	0.8350
2309	Interstitial nephritis	97	0.8195
2310	Inulinase inhibitor	4	0.9877
2311	Iodide peroxidase inhibitor	21	0.9707
2312	Iron antagonist	8	0.9962
2313	Iron-cytochrome-c reductase inhibitor	3	0.9875
2314	Irritable Bowel syndrome treatment	1423	0.9453
2315	Irritation	65	0.9154
2316	Isoamylase inhibitor	15	0.9906
2317	Isocitrate dehydrogenase (NAD+) inhibitor	28	0.9759
2318	Isocitrate dehydrogenase (NADP+) inhibitor	24	0.9914
2319	Isocitrate lyase inhibitor	26	0.9848
2320	Isoleucine-tRNA ligase inhibitor	25	0.9873
2321	Isomaltulose synthase inhibitor	6	0.9937
2322	Isopenicillin-N epimerase inhibitor	9	0.8660
2323	Isopenicillin-N synthase inhibitor	8	0.9728
2324	Isopentenyl-diphosphate DELTA-isomerase inhibitor	22	0.9985
2325	Isoquinoline 1-oxidoreductase inhibitor	4	0.9842
2326	Isovaleryl-CoA dehydrogenase inhibitor	6	0.9868
2327	JAK2 expression inhibitor	4	0.9197
2328	Janus tyrosine kinase 1 inhibitor	59	0.9725
2329	Janus tyrosine kinase 2 inhibitor	381	0.9456
2330	Janus tyrosine kinase 3 inhibitor	406	0.9861
2331	Janus tyrosine kinase inhibitor	768	0.9604
2332	JNK mitogen-activated protein kinase inhibitor	43	0.9518
2333	Juvenile-hormone esterase inhibitor	86	0.9993
2334	K(Ca) 3.1 channel activator	4	0.9869
2335	K(Ca) 3.1 channel blocker	41	0.9838
2336	K(ir) 6.2 channel activator	13	0.9506
2337	Kainate receptor 1 agonist	5	0.9984
2338	Kainate receptor 1 antagonist	296	0.9977
2339	Kainate receptor 2 antagonist	135	0.9949
2340	Kainate receptor 3 antagonist	140	0.9978
2341	Kainate receptor 4 antagonist	134	0.9972
2342	Kainate receptor 5 antagonist	152	0.9972
2343	Kainate receptor agonist	26	0.9920
2344	Kainate receptor antagonist	461	0.9942
2345	Kallikrein 13 inhibitor	10	0.9988
2346	Kallikrein 3 inhibitor	29	0.9912
2347	Kallikrein inhibitor	94	0.9569
2348	Kanamycin kinase inhibitor	3	0.9999
2349	Keratan sulfotransferase inhibitor	7	0.9990
2350	Keratolytic	34	0.9450
2351	Keratopathy	92	0.8375
2352	Keratoses actinic (solar) treatment	68	0.9534
2353	Ketohexokinase inhibitor	15	0.9422
2354	Ketol-acid reductoisomerase inhibitor	10	0.9218
2355	Ketosteroid monooxygenase inhibitor	5	0.9998
2356	Kexin inhibitor	16	0.9835
2357	Kidney function stimulant	7	0.8506
2358	Kinase inhibitor	11	0.8667
2359	Kinesin antagonist	374	0.9920
2360	Kinesin-like protein 1 inhibitor	374	0.9920
2361	KiSS-1 receptor agonist	3	1.0000
2362	Kynureninase inhibitor	42	0.9879
2363	Kynurenine 3 monooxygenase inhibitor	70	0.9991
2364	L lactate dehydrogenase A inhibitor	16	1.0000
2365	L lactate dehydrogenase A4 inhibitor	15	1.0000
2366	L lactate dehydrogenase B inhibitor	6	1.0000
2367	L lactate dehydrogenase B4 inhibitor	6	1.0000
2368	L lactate dehydrogenase C inhibitor	16	1.0000
2369	L lactate dehydrogenase C4 inhibitor	16	1.0000
2370	L lactate dehydrogenase inhibitor	32	0.9620
2371	L(+)-Tartrate dehydratase inhibitor	7	0.9996
2372	L-3-cyanoalanine synthase inhibitor	10	0.9958
2373	Laccase inhibitor	18	0.9544
2374	Lacrimal secretion stimulant	72	0.9086
2375	Lactaldehyde dehydrogenase inhibitor	6	0.9982
2376	Lactaldehyde reductase (NADPH) inhibitor	4	0.9914
2377	Lactaldehyde reductase inhibitor	4	0.9872
2378	Lactamase A inhibitor	7	0.9950
2379	Lactamase C inhibitor	8	0.9825
2380	Lactase inhibitor	3	0.8672
2381	Lactate 2-monooxygenase inhibitor	13	0.9296
2382	Lactate-malate transhydrogenase inhibitor	5	0.9954
2383	Lactose synthase inhibitor	14	0.8878
2384	Lactosylceramide alpha-2,3-sialyltransferase inhibitor	20	0.9807
2385	Lactoylglutathione lyase inhibitor	90	0.9822
2386	Laminaribiose phosphorylase inhibitor	9	0.9756
2387	L-amino-acid oxidase inhibitor	20	0.9680
2388	L-aminoadipate-semialdehyde dehydrogenase inhibitor	9	0.9950
2389	Lanosterol 14 alpha demethylase inhibitor	76	0.9487
2390	Laryngospasm	75	0.8467
2391	L-ascorbate peroxidase inhibitor	16	0.9861
2392	Lassitude treatment	18	0.9422
2393	Laxative	50	0.9352
2394	Lck kinase inhibitor	966	0.9683
2395	LDLR expression enhancer	118	0.9225
2396	LECT1 expression enhancer	9	1.0000
2397	Leishmanolysin inhibitor	6	0.8611
2398	Leucine dehydrogenase inhibitor	5	0.9172
2399	Leucine transaminase inhibitor	5	0.9933
2400	Leucine-tRNA ligase inhibitor	30	0.9359
2401	Leucolysin inhibitor	6	0.9826
2402	Leucyltransferase inhibitor	14	0.9876
2403	Leukocyte elastase inhibitor	184	0.9687
2404	Leukopenia	542	0.8200
2405	Leukopoiesis inhibitor	23	0.8407
2406	Leukopoiesis stimulant	9	0.8304
2407	Leukotriene A4 hydrolase inhibitor	322	0.9973
2408	Leukotriene agonist	5	0.9909
2409	Leukotriene antagonist	1324	0.9780
2410	Leukotriene B4 antagonist	588	0.9823
2411	Leukotriene B4 receptor 1 antagonist	466	0.9965
2412	Leukotriene B4 receptor 2 antagonist	197	0.9994
2413	Leukotriene C antagonist	206	0.9768
2414	Leukotriene C4 antagonist	195	0.9870
2415	Leukotriene D4 antagonist	532	0.9917
2416	Leukotriene E4 antagonist	40	0.9661
2417	Leukotriene synthesis inhibitor	192	0.9649
2418	Leukotriene-B4 20-monooxygenase inhibitor	5	0.9559
2419	Leukotriene-C4 synthase inhibitor	9	0.8771
2420	Levanase inhibitor	9	0.9645
2421	Levansucrase inhibitor	5	0.9519
2422	LFA antagonist	261	0.9971
2423	LFA-1 antagonist	261	0.9971
2424	L-fuconate dehydratase inhibitor	7	0.9965
2425	L-galactonolactone oxidase inhibitor	8	0.9907
2426	L-glucuronate reductase inhibitor	17	0.9560
2427	L-glutamate oxidase inhibitor	3	0.9580
2428	Licheninase inhibitor	6	0.9789
2429	L-iditol 2-dehydrogenase inhibitor	100	0.9757
2430	L-iduronidase inhibitor	5	0.9900
2431	Ligase inhibitor	5	0.9859
2432	Limulus clotting factor B inhibitor	4	0.8393
2433	Limulus clotting factor C inhibitor	4	0.9590
2434	Linoleate diol synthase inhibitor	15	0.8892
2435	Linoleate isomerase inhibitor	22	0.9954
2436	Linoleoyl-CoA desaturase inhibitor	6	0.9579
2437	Lipase inhibitor	185	0.9869
2438	Lipid metabolism regulator	131	0.8771
2439	Lipid peroxidase inhibitor	282	0.9104
2440	Lipocortins synthesis agonist	75	0.9640
2441	Lipocortins synthesis antagonist	10	0.9546
2442	Lipoprotein disorders treatment	4601	0.9534
2443	Lipoprotein lipase inhibitor	18	0.8910
2444	Lipoprotein lipase stimulant	23	0.8833
2445	Lipotropic	11	0.9770
2446	Lipoxin receptor agonist	12	0.9999
2447	Lipoxygenase inhibitor	2749	0.9711
2448	Lipoxygenase substrate	25	0.9430
2449	Liver cirrhosis treatment	53	0.9186
2450	Liver fibrosis treatment	266	0.9295
2451	Liver X receptor agonist	623	0.9932
2452	Liver X receptor alpha agonist	227	0.9891
2453	Liver X receptor antagonist	7	0.9557
2454	Liver X receptor beta agonist	335	0.9936
2455	L-lactate dehydrogenase (cytochrome) inhibitor	6	0.9981
2456	L-lysine 6-transaminase inhibitor	6	0.9910
2457	L-lysine oxidase inhibitor	4	0.9929
2458	Lombricine kinase inhibitor	6	0.9838
2459	Long-chain-acyl-CoA dehydrogenase inhibitor	6	0.9947
2460	Long-chain-aldehyde dehydrogenase inhibitor	4	0.9699
2461	Long-chain-fatty-acid-CoA ligase inhibitor	23	0.9929
2462	Loop diuretic	8	0.8686
2463	L-Serine ammonia-lyase inhibitor	14	0.9948
2464	L-threonine 3-dehydrogenase inhibitor	10	0.8788
2465	Luteinizing hormone-releasing hormone agonist	19	0.9508
2466	Luteinizing hormone-releasing hormone antagonist	969	0.9882
2467	Luteolytic	4	0.9997
2468	Lymphocytopoiesis inhibitor	10	0.9617
2469	Lysase inhibitor	10	0.8343
2470	Lysine 2,3-aminomutase inhibitor	5	0.8888
2471	Lysine 2-monooxygenase inhibitor	19	0.9720
2472	Lysine 6-dehydrogenase inhibitor	3	0.9896
2473	Lysine carboxypeptidase inhibitor	35	0.9975
2474	Lysine decarboxylase inhibitor	10	0.9901
2475	Lysine-tRNA ligase inhibitor	44	0.9844
2476	Lysophosphatidic acid receptor agonist	9	0.9975
2477	Lysophosphatidic acid receptor antagonist	78	0.9929
2478	Lysosomal Pro-X carboxypeptidase inhibitor	45	0.9830
2479	Lysostaphin inhibitor	3	0.9701
2480	Lysozyme inhibitor	13	0.9856
2481	Lysyl endopeptidase inhibitor	16	0.9831
2482	Lysyl oxidase inhibitor	10	0.8398
2483	M7G(5')pppN diphosphatase inhibitor	4	0.9998
2484	Macrocin O-methyltransferase inhibitor	9	0.9998
2485	Macrophage colony stimulating factor agonist	4	0.8201
2486	Macrophage colony stimulating factor antagonist	161	0.9935
2487	Macrophage elastase inhibitor	182	0.9791
2488	Macrophage migration inhibitory factor inhibitor	83	0.9794
2489	Macrophage scavenger receptor antagonist	7	0.9998
2490	Macrophage stimulant	3	0.9588
2491	Macular degeneration treatment	256	0.9359
2492	Magnesium-protoporphyrin IX methyltransferase inhibitor	11	0.9795
2493	Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase inhibitor	10	0.9654
2494	Magnolysin inhibitor	6	0.9991
2495	Maillard reaction inhibitor	35	0.8939
2496	Malate dehydrogenase (acceptor) inhibitor	12	0.8640
2497	Malate dehydrogenase (decarboxylating) inhibitor	20	0.9953
2498	Malate dehydrogenase (NADP+) inhibitor	9	0.9937
2499	Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) inhibitor	21	0.9952
2500	Malate dehydrogenase (oxaloacetate-decarboxylating) inhibitor	16	0.9859
2501	Malate dehydrogenase inhibitor	66	0.9351
2502	Malate oxidase inhibitor	5	0.8952
2503	Malate synthase inhibitor	18	0.9922
2504	Malate-CoA ligase inhibitor	5	0.9877
2505	Male reproductive disfunction treatment	565	0.9379
2506	Maleate hydratase inhibitor	11	0.9955
2507	Maleate isomerase inhibitor	6	0.9540
2508	Maleylacetate reductase inhibitor	4	0.9999
2509	Maleylacetoacetate isomerase inhibitor	6	0.9962
2510	Malonate-semialdehyde dehydrogenase inhibitor	3	0.9951
2511	Malonyl-CoA decarboxylase inhibitor	93	0.9962
2512	Maltose-transporting ATPase inhibitor	4	0.9801
2513	Malyl-CoA lyase inhibitor	6	0.9847
2514	Mandelate 4-monooxygenase inhibitor	11	0.9598
2515	Mandelate racemase inhibitor	27	0.9957
2516	Manganese peroxidase inhibitor	6	0.9183
2517	Mannan endo-1,4-beta-mannosidase inhibitor	3	0.9455
2518	Mannan endo-1,6-alpha-mannosidase inhibitor	4	0.9913
2519	Mannitol 2-dehydrogenase inhibitor	5	0.9998
2520	Mannitol-1-phosphatase inhibitor	3	0.9862
2521	Mannitol-1-phosphate 5-dehydrogenase inhibitor	18	0.9910
2522	Mannokinase inhibitor	9	0.9994
2523	Mannonate dehydratase inhibitor	9	0.9916
2524	Mannose isomerase inhibitor	5	0.9188
2525	Mannose-1-phosphate guanylyltransferase inhibitor	4	0.9999
2526	Mannose-6-phosphate isomerase inhibitor	109	0.9664
2527	Mannosidase inhibitor	72	0.9872
2528	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase inhibitor	8	0.9797
2529	Mannosyl-oligosaccharide 1,2-alpha-mannosidase inhibitor	22	0.9975
2530	Mannosyl-oligosaccharide glucosidase inhibitor	18	0.9970
2531	Mannotetraose 2-alpha-N-acetylglucosaminyltransferase inhibitor	4	0.9028
2532	MAO A inhibitor	463	0.9815
2533	MAO A substrate	25	0.9744
2534	MAO B inhibitor	672	0.9880
2535	MAO B substrate	17	0.9918
2536	MAO inhibitor	1124	0.9707
2537	MAP kinase 1 inhibitor	109	0.9306
2538	MAP kinase 10 inhibitor	293	0.9798
2539	MAP kinase 14 inhibitor	1528	0.9887
2540	MAP kinase 8 inhibitor	256	0.9745
2541	MAP kinase 9 inhibitor	320	0.9830
2542	MAP kinase inhibitor	2698	0.9754
2543	MAP kinase kinase 1 inhibitor	201	0.9735
2544	MAP kinase kinase 4 inhibitor	18	0.8885
2545	MAP kinase kinase 7 inhibitor	11	0.9600
2546	MAP kinase kinase inhibitor	180	0.9900
2547	MAP kinase kinase kinase inhibitor	143	0.9874
2548	MAP kinase stimulant	7	0.8717
2549	MAP3K11 inhibitor	37	0.9999
2550	MAP3K5 inhibitor	8	0.9004
2551	MAP3K8 inhibitor	56	0.9717
2552	MAP3K9 inhibitor	26	0.9987
2553	MAP-kinase-activated kinase 1 inhibitor	16	0.9664
2554	MAP-kinase-activated kinase 2 inhibitor	155	0.9629
2555	MAP-kinase-activated kinase inhibitor	180	0.9541
2556	MarA inhibitor	12	1.0000
2557	MARK1 protein inhibitor	7	1.0000
2558	Matrilysin inhibitor	331	0.9931
2559	Matriptase inhibitor	8	0.9995
2560	Matrix metalloproteinase (membrane-type) inhibitor	1124	0.9909
2561	Matrix metalloproteinase 1 (membrane-type) inhibitor	354	0.9913
2562	Matrix metalloproteinase 1 inhibitor	1586	0.9923
2563	Matrix metalloproteinase 2 (membrane-type) inhibitor	18	0.9967
2564	Matrix metalloproteinase 3 (membrane-type) inhibitor	878	0.9925
2565	Matrix metalloproteinase inhibitor	2580	0.9886
2566	Mcl-1 antagonist	989	0.9589
2567	MDM2 inhibitor	180	0.9377
2568	Mediator release inhibitor	146	0.8975
2569	Melanin inhibitor	32	0.9342
2570	Melanin-concentrating hormone receptor 1 antagonist	1035	0.9906
2571	Melanin-concentrating hormone receptor antagonist	1039	0.9906
2572	Melanocortin 4 antagonist	377	0.9970
2573	Melanocortin agonist	16	0.9600
2574	Melanocortin antagonist	510	0.9919
2575	Melanocortin MC-4 agonist	10	0.9830
2576	Melatonin 1 agonist	27	0.9959
2577	Melatonin 1 antagonist	560	0.9969
2578	Melatonin 1a antagonist	404	0.9974
2579	Melatonin 1b antagonist	127	0.9941
2580	Melatonin 2 agonist	15	0.9996
2581	Melatonin 2 antagonist	233	0.9991
2582	Melatonin 3 antagonist	100	0.9988
2583	Melatonin 5 antagonist	68	0.9995
2584	Melatonin agonist	98	0.9975
2585	Melatonin antagonist	789	0.9964
2586	Membrane dipeptidase inhibitor	43	0.9554
2587	Membrane integrity agonist	15	0.8324
2588	Membrane integrity antagonist	56	0.8667
2589	Membrane permeability enhancer	44	0.8802
2590	Membrane permeability inhibitor	40	0.8262
2591	Membrane-oligosaccharide glycerophosphotransferase inhibitor	6	0.9989
2592	Menopausal disorders treatment	53	0.8664
2593	Menstruation disorders treatment	235	0.9274
2594	Mental retardation treatment	7	0.9912
2595	Meprin A inhibitor	13	0.9747
2596	Meprin B inhibitor	3	0.9810
2597	Metabolic disease treatment	164	0.9214
2598	Metallocarboxypeptidase D inhibitor	7	0.9578
2599	Metalloproteinase inhibitor	2981	0.9865
2600	Metalloproteinase-11 inhibitor	31	0.9818
2601	Metalloproteinase-2 inhibitor	1812	0.9872
2602	Metalloproteinase-3 inhibitor	951	0.9924
2603	Metalloproteinase-9 inhibitor	1837	0.9895
2604	Methane monooxygenase inhibitor	13	0.9012
2605	Methanol dehydrogenase inhibitor	3	0.9840
2606	Methemoglobinemia	16	0.9551
2607	Methenyltetrahydrofolate cyclohydrolase inhibitor	7	0.9926
2608	Methionine adenosyltransferase inhibitor	27	0.9927
2609	Methionine decarboxylase inhibitor	6	0.9907
2610	Methionine-tRNA ligase inhibitor	139	0.9928
2611	Methionyl aminopeptidase 1 inhibitor	186	0.9978
2612	Methionyl aminopeptidase 2 inhibitor	230	0.9947
2613	Methionyl aminopeptidase inhibitor	455	0.9956
2614	Methionyl-tRNA formyltransferase inhibitor	7	0.9997
2615	Methylamine-glutamate N-methyltransferase inhibitor	3	0.9601
2616	Methylaspartate ammonia-lyase inhibitor	8	0.9838
2617	Methylaspartate mutase inhibitor	8	0.9991
2618	Methylcrotonoyl-CoA carboxylase inhibitor	11	0.9878
2619	Methylenetetrahydrofolate dehydrogenase (NADP+) inhibitor	10	0.9890
2620	Methylenetetrahydrofolate reductase (NADPH) inhibitor	10	0.9238
2621	Methylglutamate dehydrogenase inhibitor	7	0.9880
2622	Methylglyoxal synthase inhibitor	15	0.9982
2623	Methylmalonyl-CoA carboxytransferase inhibitor	7	0.9997
2624	Methylmalonyl-CoA decarboxylase inhibitor	7	0.9903
2625	Methylmalonyl-CoA epimerase inhibitor	9	0.9990
2626	Methylmalonyl-CoA mutase inhibitor	11	0.9912
2627	Methylthioadenosine nucleosidase inhibitor	16	0.9942
2628	Methyltransferase inhibitor	5	0.9997
2629	Methyltransferase substrate	4	0.9873
2630	Methylumbelliferyl-acetate deacetylase inhibitor	7	0.8731
2631	Mevalonate kinase inhibitor	11	0.9828
2632	MexAB-OprM inhibitor	3	1.0000
2633	Microbial collagenase inhibitor	514	0.9946
2634	Microsomal triglyceride transfer protein inhibitor	423	0.9992
2635	Microtubule formation inhibitor	320	0.9397
2636	Microtubule stabilization	142	0.9921
2637	Mineralocorticoid	16	0.9998
2638	Mineralocorticoid antagonist	441	0.9900
2639	Miotic	122	0.8950
2640	Mitochondrial intermediate peptidase inhibitor	6	0.9787
2641	Mitochondrial processing peptidase inhibitor	6	0.8265
2642	MMP9 expression inhibitor	16	0.8764
2643	MO15-related protein kinase Pfmrk inhibitor	18	0.9230
2644	Monoamine oxidase substrate	45	0.9832
2645	Monoamine uptake inhibitor	41	0.9159
2646	Monocarboxylic acid transporter 1 inhibitor	6	0.9733
2647	Monocarboxylic acid transporter inhibitor	6	0.9733
2648	Monodehydroascorbate reductase (NADH) inhibitor	17	0.9197
2649	Monophenol monooxygenase inhibitor	113	0.9637
2650	Mood disorders treatment	8303	0.9181
2651	Morphine 6-dehydrogenase inhibitor	13	0.9582
2652	Motilin receptor agonist	101	0.9920
2653	Motilin receptor antagonist	78	0.9999
2654	Movement disorders treatment	43	0.9388
2655	mRNA (guanine-N7-)-methyltransferase inhibitor	18	0.9655
2656	mRNA (nucleoside-2'-O-)-methyltransferase inhibitor	16	1.0000
2657	mTOR inhibitor	643	0.9941
2658	Mucinaminylserine mucinaminidase inhibitor	5	0.8302
2659	Mucolytic	104	0.9210
2660	Mucomembranous protector	33	0.8045
2661	Muconate cycloisomerase inhibitor	4	0.9976
2662	Mucorpepsin inhibitor	5	0.9649
2663	Mucositis treatment	14	0.8398
2664	Multidrug resistance-associated protein 1 inhibitor	223	0.9667
2665	Multidrug resistance-associated protein inhibitor	224	0.9623
2666	Multiple inositol-polyphosphate phosphatase inhibitor	5	0.9998
2667	Multiple organ failure	3	0.8848
2668	Multiple sclerosis treatment	959	0.8914
2669	Muramoyltetrapeptide carboxypeptidase inhibitor	5	0.9334
2670	Muscle relaxant	395	0.9217
2671	Muscle weakness	191	0.8482
2672	Muscular dystrophy treatment	62	0.8660
2673	Mutagenic	3542	0.9713
2674	Mutagenic, Salmonella	3302	0.9740
2675	Myc inhibitor	9	0.8699
2676	Mycodextranase inhibitor	6	0.9945
2677	Mycolysin inhibitor	3	0.9974
2678	Mycothiol-S-conjugate amidase inhibitor	3	0.8929
2679	Mydriatic	211	0.9042
2680	Myelin associated glycoprotein antagonist	4	1.0000
2681	Myeloblastin inhibitor	4	0.9831
2682	Myocardial infarction treatment	600	0.9504
2683	Myocardial ischemia treatment	1664	0.9511
2684	Myocarditis	25	0.8236
2685	Myoclonus	79	0.8420
2686	Myosin ATPase inhibitor	11	0.8730
2687	Myosin-light-chain-phosphatase inhibitor	6	0.9757
2688	Myristoyl transferase 1 inhibitor	73	0.9972
2689	Myristoyl transferase inhibitor	93	0.9975
2690	Myt1 kinase inhibitor	7	1.0000
2691	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase inhibitor	8	0.9837
2692	N-(long-chain-acyl)ethanolamine deacylase inhibitor	7	0.9738
2693	N4-(beta-N-acetylglucosaminyl)-L-asparaginase inhibitor	10	0.9844
2694	N6-methyl-lysine oxidase inhibitor	4	0.9843
2695	Na+ K+ transporting ATPase inhibitor	165	0.9854
2696	Na+-transporting two-sector ATPase inhibitor	7	0.8289
2697	N-Acetylated alpha-linked acidic dipeptidase inhibitor	158	0.9986
2698	N-acetylgalactosamine-4-sulfatase inhibitor	3	0.9999
2699	N-acetyl-gamma-glutamyl-phosphate reductase inhibitor	3	0.9893
2700	N-acetylglucosamine kinase inhibitor	15	0.9929
2701	N-acetylglucosamine-6-phosphate deacetylase inhibitor	10	0.9938
2702	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase inhibitor	6	0.9978
2703	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase inhibitor	3	0.9403
2704	N-acetyllactosamine synthase inhibitor	6	0.9669
2705	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase inhibitor	5	0.9707
2706	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase inhibitor	7	0.9970
2707	N-acetylmuramoyl-L-alanine amidase inhibitor	11	0.9970
2708	N-acetylneuraminate 4-O-acetyltransferase inhibitor	3	0.9785
2709	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase inhibitor	6	0.8127
2710	N-acetylneuraminate lyase inhibitor	14	0.9926
2711	N-acetylneuraminate synthase inhibitor	4	0.9911
2712	N-Acyl-D-amino-acid deacylase inhibitor	4	0.9890
2713	N-Acyl-D-aspartate deacylase inhibitor	3	0.9850
2714	N-acylmannosamine kinase inhibitor	5	0.8834
2715	N-acylneuraminate cytidylyltransferase inhibitor	15	0.9930
2716	NAD(P)+ transhydrogenase (AB-specific) inhibitor	31	0.9784
2717	NAD(P)+ transhydrogenase (B-specific) inhibitor	11	0.9630
2718	NAD(P)+-arginine ADP-ribosyltransferase inhibitor	11	0.8620
2719	NAD(P)H dehydrogenase (quinone) 1 inhibitor	50	0.9986
2720	NAD(P)H dehydrogenase (quinone) inhibitor	147	0.9804
2721	NAD+ diphosphatase inhibitor	11	0.9920
2722	NAD+ kinase inhibitor	17	0.9634
2723	NAD+ nucleosidase inhibitor	19	0.9937
2724	NAD+ synthase (glutamine-hydrolysing) inhibitor	4	0.9832
2725	NAD+-dinitrogen-reductase ADP-D-ribosyltransferase inhibitor	3	0.9934
2726	NADH dehydrogenase inhibitor	17	0.9554
2727	NADH kinase inhibitor	3	0.9754
2728	NADH oxidase inhibitor	18	0.9999
2729	NADPH oxidase inhibitor	76	0.9679
2730	NADPH oxidoreductase inhibitor	20	0.9894
2731	NADPH peroxidase inhibitor	4	0.9089
2732	NADPH-cytochrome-c2 reductase inhibitor	3	0.8785
2733	NADPH-ferrihemoprotein reductase inhibitor	10	0.8683
2734	Nail discoloration	4	0.8386
2735	Naphthalene 1,2-dioxygenase inhibitor	3	0.9674
2736	Narcolepsy treatment	12	0.9626
2737	Narcotic antagonist	71	0.9676
2738	Nardilysin inhibitor	8	0.9337
2739	NAT1 substrate	20	0.9948
2740	NAT2 substrate	35	0.9874
2741	Nausea	1042	0.8186
2742	Nav1.1 sodium channel blocker	164	0.9608
2743	Nav1.2 sodium channel blocker	222	0.9594
2744	Nav1.3 sodium channel blocker	160	0.9603
2745	Nav1.4 sodium channel blocker	23	0.9885
2746	Nav1.5 sodium channel blocker	91	0.9313
2747	Nav1.7 sodium channel blocker	97	0.9655
2748	Nav1.8 sodium channel blocker	190	0.9597
2749	N-benzyloxycarbonylglycine hydrolase inhibitor	6	0.8806
2750	N-Carbamoyl-D-amino acid hydrolase inhibitor	5	0.9863
2751	N-carbamoyl-L-amino-acid hydrolase inhibitor	10	0.9833
2752	Necroptosis inhibitor	6	0.9424
2753	Necrosis	183	0.8038
2754	Necrosis treatment	6	1.0000
2755	Neolactotetraosylceramide alpha-2,3-sialyltransferase inhibitor	6	0.9933
2756	Nephritis	124	0.8164
2757	Nephrotic syndrome	56	0.8089
2758	Nephrotoxic	787	0.8402
2759	Nerve growth factor antagonist	40	0.9928
2760	Neuraminidase (Influenza A) inhibitor	166	0.9999
2761	Neuraminidase (Influenza B) inhibitor	65	0.9998
2762	Neuraminidase (influenza) inhibitor	195	0.9977
2763	Neuraminidase inhibitor	309	0.9875
2764	Neurodegenerative diseases treatment	5571	0.8598
2765	Neurokinin 1 antagonist	1433	0.9957
2766	Neurokinin 2 antagonist	708	0.9903
2767	Neurokinin 3 antagonist	344	0.9918
2768	Neurokinin antagonist	2057	0.9926
2769	Neuroleptic malignant syndrome	51	0.9007
2770	Neurolysin inhibitor	25	0.9859
2771	Neuronal nicotinic receptor antagonist	739	0.9941
2772	Neuronal nitric-oxide synthase inhibitor	437	0.9966
2773	Neuropathy treatment	21	0.9992
2774	Neuropeptide agonist	16	0.9100
2775	Neuropeptide antagonist	1444	0.9687
2776	Neuropeptide FF agonist	8	0.8792
2777	Neuropeptide FF antagonist	66	0.9979
2778	Neuropeptide FF1 antagonist	30	0.9972
2779	Neuropeptide FF2 agonist	8	0.8792
2780	Neuropeptide S antagonist	4	0.8927
2781	Neuropeptide Y agonist	7	0.9577
2782	Neuropeptide Y antagonist	1374	0.9679
2783	Neuropeptide Y1 agonist	6	1.0000
2784	Neuropeptide Y1 antagonist	389	0.9539
2785	Neuropeptide Y2 antagonist	117	0.8752
2786	Neuropeptide Y4 antagonist	6	0.8028
2787	Neuropeptide Y5 antagonist	837	0.9923
2788	Neuropsin inhibitor	5	0.9891
2789	Neurotensin 1 receptor agonist	3	0.9981
2790	Neurotensin 1 receptor antagonist	53	0.9740
2791	Neurotensin 2 receptor antagonist	27	1.0000
2792	Neurotensin 3 receptor antagonist	25	1.0000
2793	Neurotensin receptor agonist	16	0.9984
2794	Neurotensin receptor antagonist	113	0.9936
2795	Neurotoxic	638	0.8575
2796	Neurotransmitter antagonist	9	0.8311
2797	Neurotransmitter uptake inhibitor	3	0.8987
2798	Neurotrophic factor	468	0.9612
2799	Neurotrophic factor enhancer	74	0.9296
2800	Neutral endopeptidase inhibitor	698	0.9953
2801	Neutropenia treatment	54	0.9997
2802	Neutrophil collagenase inhibitor	746	0.9882
2803	Neutrophil fMLF receptor antagonist	23	1.0000
2804	Neutrophilic dermatosis (Sweet's syndrome)	4	0.8396
2805	NF-E2-related factor 2 stimulant	10	0.9493
2806	N-formylglutamate deformylase inhibitor	16	0.9946
2807	N-formylmethionyl-peptidase inhibitor	3	0.9691
2808	N-hydroxy-2-acetamidofluorene reductase inhibitor	3	0.9809
2809	N-hydroxyarylamine O-acetyltransferase inhibitor	11	0.8409
2810	Nicotinamidase inhibitor	24	0.9839
2811	Nicotinamide phosphoribosyltransferase inhibitor	13	0.9667
2812	Nicotinamide-nucleotide adenylyltransferase inhibitor	7	0.9916
2813	Nicotinamide-nucleotide amidase inhibitor	6	1.0000
2814	Nicotinate dehydrogenase inhibitor	6	0.8542
2815	Nicotinate phosphoribosyltransferase inhibitor	17	0.9952
2816	Nicotinate-nucleotide diphosphorylase (carboxylating) inhibitor	32	0.9941
2817	Nicotine dehydrogenase inhibitor	5	0.8152
2818	Nicotinic acid receptor 1 agonist	102	0.9872
2819	Nicotinic acid receptor 2 agonist	26	0.9962
2820	Nicotinic acid receptor agonist	201	0.9929
2821	Nicotinic alpha2beta2 receptor antagonist	4	0.8885
2822	Nicotinic alpha2beta4 receptor agonist	4	0.8620
2823	Nicotinic alpha3beta4 receptor agonist	12	0.9911
2824	Nicotinic alpha4 receptor agonist	16	0.9998
2825	Nicotinic alpha4beta2 receptor agonist	34	0.9986
2826	Nicotinic alpha4beta2 receptor antagonist	18	0.9430
2827	Nicotinic alpha4beta4 receptor agonist	3	0.9002
2828	Nicotinic alpha6 receptor agonist	3	0.9964
2829	Nicotinic alpha6beta3beta4alpha5 receptor antagonist	3	0.8470
2830	Nicotinic alpha7 receptor agonist	535	0.9938
2831	Nicotinic neuronal receptor agonist	611	0.9908
2832	Nicotinic receptor alpha7 subunit antagonist	59	0.9913
2833	Niemann-Pick C1-like 1 protein antagonist	23	0.9197
2834	Nitrate reductase (cytochrome) inhibitor	11	0.8698
2835	Nitrate reductase inhibitor	30	0.9388
2836	Nitric oxide antagonist	146	0.9455
2837	Nitric oxide donor	197	0.9939
2838	Nitric oxide scavenger	4	0.9437
2839	Nitric-oxide synthase inhibitor	1075	0.9776
2840	Nitric-oxide synthase stimulant	19	0.9072
2841	Nitrilase inhibitor	18	0.9832
2842	Nitrile hydratase inhibitor	22	0.9874
2843	Nitrite reductase (NO-forming) inhibitor	3	0.9543
2844	Nitrite reductase [NAD(P)H] inhibitor	18	0.8771
2845	NMDA 2 receptor antagonist	941	0.9898
2846	NMDA 2A receptor antagonist	568	0.9947
2847	NMDA 2B receptor antagonist	396	0.9899
2848	NMDA receptor agonist	164	0.9811
2849	NMDA receptor antagonist	4021	0.9799
2850	NMDA receptor glutamate site antagonist	41	0.9986
2851	NMDA receptor glycine site agonist	127	0.9885
2852	NMDA receptor glycine site antagonist	586	0.9975
2853	NMDA receptor glycine site B antagonist	5	0.9992
2854	NMDA receptor phencyclidine site antagonist	152	0.9986
2855	NMDA receptor polyamine site agonist	3	0.9994
2856	NMDA receptor polyamine site antagonist	5	0.9416
2857	N-methyl-2-oxoglutaramate hydrolase inhibitor	9	0.9714
2858	N-methylhydantoinase (ATP-hydrolysing) inhibitor	5	0.9685
2859	NMN nucleosidase inhibitor	16	0.9928
2860	Nociceptin (N/OFQ) receptor agonist	8	0.9999
2861	Nociceptin (N/OFQ) receptor antagonist	320	0.9961
2862	Non mutagenic, Salmonella	450	0.9209
2863	Non-steroidal antiinflammatory agent	1075	0.9162
2864	Nootropic	1128	0.7596
2865	NOS2 expression inhibitor	43	0.9349
2866	NOS3 expression enhancer	73	0.9570
2867	NTPase/helicase (JEV) inhibitor	3	0.9998
2868	NTPase/helicase (WNF) inhibitor	9	0.9999
2869	Nuclear receptor subfamily 4, group A, member 2 agonist	24	0.9977
2870	Nuclease inhibitor	14	0.9615
2871	Nucleoside deoxyribosyltransferase inhibitor	8	0.9979
2872	Nucleoside oxidase (H2O2-forming) inhibitor	6	0.9676
2873	Nucleoside phosphoacylhydrolase inhibitor	4	0.9878
2874	Nucleoside transporters inhibitor	18	0.9988
2875	Nucleoside-diphosphatase inhibitor	10	0.9702
2876	Nucleoside-triphosphate diphosphatase inhibitor	7	0.9999
2877	Nucleoside-triphosphate-adenylate kinase inhibitor	7	0.9856
2878	Nucleotidase inhibitor	6	0.9447
2879	Nucleotide diphosphatase inhibitor	37	0.9794
2880	Nucleotide metabolism regulator	138	0.8675
2881	Nucleotidyltransferase (FIV) inhibitor	15	0.9961
2882	Nucleotidyltransferase inhibitor	18	0.9981
2883	O6-alkylguanine-DNA alkyltransferase inhibitor	130	0.9946
2884	O-acetylhomoserine aminocarboxypropyltransferase inhibitor	15	0.9789
2885	O-aminophenol oxidase inhibitor	12	0.9137
2886	Obsessive-compulsive disorder treatment	68	0.9473
2887	Occult bleeding	3	0.8960
2888	Octadecanal decarbonylase inhibitor	6	0.9942
2889	Octopamine agonist	67	0.9994
2890	Octopamine antagonist	5	0.8008
2891	Ocular toxicity	639	0.8211
2892	Oleamide hydrolase inhibitor	308	0.9909
2893	Oligo-1,6-glucosidase inhibitor	24	0.9900
2894	Oligonucleotidase inhibitor	10	0.9941
2895	Oligopeptidase B inhibitor	7	0.9716
2896	Omega-amidase inhibitor	8	0.9904
2897	Omptin inhibitor	4	0.8813
2898	Opheline kinase inhibitor	3	0.9794
2899	Ophthalmic drug	1892	0.8946
2900	Opine dehydrogenase inhibitor	4	0.9784
2901	Opioid delta 1 receptor antagonist	11	0.9549
2902	Opioid delta 2 receptor antagonist	12	0.9995
2903	Opioid dependency treatment	36	0.8757
2904	Opioid kappa 1 receptor antagonist	90	0.9915
2905	Opioid kappa 2 receptor antagonist	14	1.0000
2906	Opioid kappa 2b receptor antagonist	14	1.0000
2907	Opioid kappa 3 receptor antagonist	10	0.8496
2908	Opioid mu 1 receptor antagonist	21	0.9793
2909	Opioid mu 2 receptor antagonist	24	0.9853
2910	Optic neuritis	60	0.7812
2911	Optic neuropathy	68	0.7759
2912	Orcinol 2-monooxygenase inhibitor	7	0.9991
2913	Orexin receptor 1 antagonist	475	0.9601
2914	Orexin receptor 2 antagonist	244	0.9988
2915	Orexin receptor antagonist	742	0.9670
2916	Ornithine carbamoyltransferase inhibitor	40	0.9901
2917	Ornithine cyclodeaminase inhibitor	3	0.9881
2918	Ornithine decarboxylase inhibitor	102	0.9804
2919	Ornithine-oxo-acid transaminase inhibitor	39	0.9602
2920	Orotate phosphoribosyltransferase inhibitor	36	0.9947
2921	Orotate reductase (NADH) inhibitor	8	0.9867
2922	Orotate reductase (NADPH) inhibitor	5	0.9974
2923	Orotidylate decarboxylase inhibitor	4	0.9991
2924	Orsellinate decarboxylase inhibitor	5	1.0000
2925	Oryzin inhibitor	10	0.9179
2926	Osmotic diuretic	6	0.9985
2927	Osteoarthritis treatment	279	0.9500
2928	Osteoclast antagonist	81	0.9822
2929	Ototoxicity	43	0.8737
2930	Ovulation inhibitor	15	0.8575
2931	Oxalate oxidase inhibitor	13	0.9477
2932	Oxaloacetate decarboxylase inhibitor	15	0.9927
2933	Oxaloacetate tautomerase inhibitor	15	0.9960
2934	Oxidizing agent	16	0.9542
2935	Oxidoreductase inhibitor	82	0.8443
2936	Oxoglutarate dehydrogenase (lipoamide) inhibitor	17	0.9886
2937	Oxygen scavenger	9	0.8446
2938	Oxytocic	20	0.9050
2939	Oxytocin agonist	16	0.9563
2940	Oxytocin antagonist	793	0.9907
2941	P2 nucleoside transporter inhibitor	11	1.0000
2942	p21-activated kinase 1 inhibitor	9	0.8763
2943	p21-activated kinase 4 inhibitor	20	0.9510
2944	p21-activated kinase inhibitor	22	0.9248
2945	P3 purinoceptor-like protein antagonist	35	0.9999
2946	p38 MAP kinase inhibitor	423	0.9769
2947	p53 inhibitor	27	0.9643
2948	Paget's disease treatment	43	0.9791
2949	Pain	970	0.8176
2950	Palmitoyl-CoA hydrolase inhibitor	44	0.9787
2951	Palpitation	31	0.8475
2952	Pancreatic disorders treatment	148	0.9072
2953	Pancreatic elastase inhibitor	10	0.8008
2954	Pancreatic endopeptidase E inhibitor	6	0.9896
2955	Pancreatic ribonuclease inhibitor	10	0.9144
2956	Panic	13	0.9091
2957	Pantetheine-phosphate adenylyltransferase inhibitor	16	0.9666
2958	Pantoate 4-dehydrogenase inhibitor	3	0.9938
2959	Pantoate-beta-alanine ligase inhibitor	39	0.9736
2960	Pantothenase inhibitor	10	0.9887
2961	Pantothenate kinase inhibitor	18	0.9987
2962	Papillary necrosis	4	0.9968
2963	Pappalysin-1 inhibitor	4	0.9702
2964	Para amino benzoic acid antagonist	8	0.8823
2965	Paralysis	134	0.8005
2966	Paraoxonase substrate	5	0.9870
2967	Parathyroid hormone antagonist	19	0.9854
2968	Parathyroid hormone secretion stimulant	71	0.9981
2969	Parkinsonism	27	0.8627
2970	P-benzoquinone reductase (NADPH) inhibitor	8	0.8491
2971	Pectate lyase inhibitor	11	0.9810
2972	Pectin lyase inhibitor	11	0.9870
2973	Pediculicide	10	0.9647
2974	Penicillin amidase inhibitor	10	0.9579
2975	Penicillopepsin inhibitor	14	0.9713
2976	Pepsin inhibitor	80	0.9947
2977	Peptide agonist	3	0.9471
2978	Peptide alpha-N-acetyltransferase inhibitor	6	0.9354
2979	Peptide deformylase inhibitor	181	0.9908
2980	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase inhibitor	6	0.9053
2981	Peptide-tryptophan 2,3-dioxygenase inhibitor	9	0.9828
2982	Peptidoglycan beta-N-acetylmuramidase inhibitor	3	0.9939
2983	Peptidoglycan glycosyltransferase inhibitor	4	0.9178
2984	Peptidylamidoglycolate lyase inhibitor	5	0.9887
2985	Peptidyl-dipeptidase B inhibitor	7	0.8547
2986	Peptidyl-dipeptidase Dcp inhibitor	6	0.9418
2987	Peptidyl-glycinamidase inhibitor	11	0.9756
2988	Peptidylglycine monooxygenase inhibitor	38	0.9864
2989	Peptidyl-Lys metalloendopeptidase inhibitor	22	0.9503
2990	Peptidyl-prolyl cis-trans isomerase inhibitor	388	0.9928
2991	Peptidyltransferase inhibitor	20	0.8964
2992	Periodontitis treatment	20	0.9723
2993	Peristaltic stimulant	174	0.9472
2994	Peroxidase inhibitor	16	0.9313
2995	Peroxidase substrate	33	0.9183
2996	Peroxisome proliferator-activated receptor agonist	1958	0.9883
2997	Peroxisome proliferator-activated receptor alpha agonist	1005	0.9919
2998	Peroxisome proliferator-activated receptor alpha antagonist	383	0.9956
2999	Peroxisome proliferator-activated receptor antagonist	966	0.9782
3000	Peroxisome proliferator-activated receptor delta agonist	409	0.9963
3001	Peroxisome proliferator-activated receptor delta antagonist	260	0.9964
3002	Peroxisome proliferator-activated receptor gamma agonist	935	0.9861
3003	Peroxisome proliferator-activated receptor gamma antagonist	810	0.9757
3004	PfA-M1 aminopeptidase inhibitor	55	0.9231
3005	pFOX inhibitor	5	0.9996
3006	P-glycoprotein 1 inhibitor	450	0.9359
3007	P-glycoprotein inhibitor	644	0.9340
3008	P-glycoprotein substrate	59	0.8506
3009	Phenol 2-monooxygenase inhibitor	25	0.9598
3010	Phenol O-methyltransferase inhibitor	3	0.9537
3011	Phenylacetaldehyde dehydrogenase inhibitor	5	0.9887
3012	Phenylacetate-CoA ligase inhibitor	8	0.9782
3013	Phenylalanine 2-monooxygenase inhibitor	6	0.9992
3014	Phenylalanine 4-hydroxylase inhibitor	30	0.9788
3015	Phenylalanine decarboxylase inhibitor	8	0.9827
3016	Phenylalanine dehydrogenase inhibitor	19	0.9872
3017	Phenylalanine racemase (ATP-hydrolysing) inhibitor	10	0.9787
3018	Phenylalanine(histidine) transaminase inhibitor	4	0.9823
3019	Phenylalanine-tRNA ligase inhibitor	22	0.9896
3020	Phenylethanolamine N methyltransferase inhibitor	88	0.9979
3021	Phenylpyruvate decarboxylase inhibitor	3	0.9938
3022	Phenylpyruvate tautomerase inhibitor	5	1.0000
3023	Phloroglucinol reductase inhibitor	13	0.9168
3024	Phobic disorders treatment	4	0.8161
3025	Phosphatase inhibitor	9	0.8017
3026	Phosphate acetyltransferase inhibitor	14	0.9845
3027	Phosphate butyryltransferase inhibitor	4	1.0000
3028	Phosphate transporter inhibitor	26	0.9813
3029	Phosphatidate cytidylyltransferase inhibitor	17	0.9831
3030	Phosphatidate phosphatase inhibitor	24	0.9469
3031	Phosphatidylcholine-retinol O-acyltransferase inhibitor	4	0.8246
3032	Phosphatidylcholine-sterol O-acyltransferase inhibitor	16	0.8973
3033	Phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase inhibitor	3	0.9961
3034	Phosphatidylglycerophosphatase inhibitor	8	0.9716
3035	Phosphatidylinositol 3-kinase alpha inhibitor	622	0.9889
3036	Phosphatidylinositol 3-kinase beta inhibitor	303	0.9901
3037	Phosphatidylinositol 3-kinase delta inhibitor	290	0.9889
3038	Phosphatidylinositol 3-kinase gamma inhibitor	520	0.9938
3039	Phosphatidylinositol 3-kinase inhibitor	1201	0.9863
3040	Phosphatidylinositol 3-kinase stimulant	6	0.8208
3041	Phosphatidylinositol diacylglycerol-lyase inhibitor	12	0.9256
3042	Phosphatidylinositol kinase inhibitor	1235	0.9859
3043	Phosphatidylserine decarboxylase inhibitor	10	0.9343
3044	Phosphoadenylylsulfatase inhibitor	5	0.9979
3045	Phosphodiesterase 10A inhibitor	106	0.9912
3046	Phosphodiesterase 11A inhibitor	68	0.9943
3047	Phosphodiesterase 1B inhibitor	223	0.9776
3048	Phosphodiesterase 3A inhibitor	257	0.9835
3049	Phosphodiesterase 4A inhibitor	744	0.9861
3050	Phosphodiesterase 4B inhibitor	1050	0.9875
3051	Phosphodiesterase 4C inhibitor	925	0.9889
3052	Phosphodiesterase 4D inhibitor	1053	0.9882
3053	Phosphodiesterase 5A inhibitor	469	0.9829
3054	Phosphodiesterase 6A inhibitor	176	0.9987
3055	Phosphodiesterase 6B inhibitor	106	0.9979
3056	Phosphodiesterase 7A inhibitor	55	0.9865
3057	Phosphodiesterase 9A inhibitor	32	0.9995
3058	Phosphodiesterase I inhibitor	403	0.9656
3059	Phosphodiesterase II inhibitor	120	0.9740
3060	Phosphodiesterase III inhibitor	1127	0.9863
3061	Phosphodiesterase inhibitor	5905	0.9709
3062	Phosphodiesterase IV inhibitor	3418	0.9868
3063	Phosphodiesterase IX inhibitor	35	0.9998
3064	Phosphodiesterase V inhibitor	1029	0.9844
3065	Phosphodiesterase VI inhibitor	260	0.9971
3066	Phosphodiesterase VII inhibitor	167	0.9837
3067	Phosphodiesterase X inhibitor	106	0.9912
3068	Phosphodiesterase XI inhibitor	68	0.9943
3069	Phosphoenolpyruvate carboxykinase (ATP) inhibitor	34	0.9456
3070	Phosphoenolpyruvate carboxykinase (diphosphate) inhibitor	8	0.9947
3071	Phosphoenolpyruvate carboxykinase (GTP) inhibitor	25	0.9970
3072	Phosphoenolpyruvate carboxylase inhibitor	73	0.9892
3073	Phosphoenolpyruvate mutase inhibitor	3	0.9865
3074	Phosphoenolpyruvate-protein phosphotransferase inhibitor	4	0.9901
3075	Phosphofructokinase-1 inhibitor	33	0.9847
3076	Phosphoglucomutase inhibitor	16	0.9947
3077	Phosphogluconate 2-dehydrogenase inhibitor	14	0.9989
3078	Phosphogluconate dehydrogenase (decarboxylating) inhibitor	56	0.9901
3079	Phosphoglycerate dehydrogenase inhibitor	16	0.9960
3080	Phosphoglycerate kinase inhibitor	189	0.9956
3081	Phosphoglycerate mutase inhibitor	10	0.9910
3082	Phosphoglycerate phosphatase inhibitor	6	0.9995
3083	Phosphoglycolate phosphatase inhibitor	12	0.9928
3084	Phosphoinositide 5-phosphatase inhibitor	11	0.9058
3085	Phosphoinositide dependent kinase 1 inhibitor	39	0.9814
3086	Phosphoinositide phospholipase C inhibitor	9	0.9386
3087	Phosphoketolase inhibitor	10	0.9974
3088	Phospholipase A1 inhibitor	16	0.9449
3089	Phospholipase A2 IIa inhibitor	127	0.9905
3090	Phospholipase A2 inhibitor	541	0.9648
3091	Phospholipase C inhibitor	51	0.9282
3092	Phospholipase D inhibitor	107	0.9686
3093	Phospholipase D1 inhibitor	41	0.9606
3094	Phospholipase D2 inhibitor	86	0.9872
3095	Phospholipase inhibitor	687	0.9604
3096	Phospholipid-translocating ATPase inhibitor	4	0.8761
3097	Phosphomannomutase inhibitor	17	0.9979
3098	Phosphomevalonate kinase inhibitor	14	0.9924
3099	Phospho-N-acetylmuramoyl-pentapeptide-transferase inhibitor	127	0.9967
3100	Phosphonoacetate hydrolase inhibitor	6	0.9919
3101	Phosphopantothenoylcysteine decarboxylase inhibitor	7	0.9411
3102	Phosphopyruvate hydratase inhibitor	7	0.9997
3103	Phosphoribosylformylglycinamidine cyclo-ligase inhibitor	3	0.9999
3104	Phosphoribosylformylglycinamidine synthase inhibitor	7	0.9980
3105	Phosphoribosylglycinamide formyltransferase inhibitor	121	0.9998
3106	Phosphoribulokinase inhibitor	10	0.9931
3107	Phosphorylase a inhibitor	26	0.9908
3108	Phosphorylase b inhibitor	5	0.9637
3109	Phosphorylase inhibitor	279	0.9853
3110	Phosphorylase kinase inhibitor	57	0.9721
3111	Phosphoserine phosphatase inhibitor	10	0.9887
3112	Phosphoserine transaminase inhibitor	5	0.9991
3113	Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) inhibitor	43	0.9523
3114	Photoallergy dermatitis	58	0.8445
3115	Photosensitizer	29	0.9440
3116	Phthalate 4,5-dioxygenase inhibitor	3	0.8714
3117	Phytanoyl-CoA dioxygenase inhibitor	3	0.9786
3118	Picornain 2A inhibitor	10	0.9809
3119	Picornain 3C inhibitor	8	0.9779
3120	Piloerection	13	0.8744
3121	Pim kinase inhibitor	150	0.9643
3122	Pim-1 kinase inhibitor	91	0.9473
3123	Pim-2 kinase inhibitor	60	0.9538
3124	Pim-3 kinase inhibitor	19	0.9493
3125	Pin1 inhibitor	5	0.8888
3126	Pitrilysin inhibitor	10	0.9409
3127	Plasmanylethanolamine desaturase inhibitor	8	0.9804
3128	Plasmepsin I inhibitor	63	0.9997
3129	Plasmepsin II inhibitor	99	0.9741
3130	Plasmepsin inhibitor	108	0.9755
3131	Plasmin inhibitor	323	0.9876
3132	Plasminogen activator inhibitor	134	0.9857
3133	Plasminogen activator inhibitor antagonist	165	0.9843
3134	Plasminogen activator stimulant	14	0.9719
3135	Plastoquinol-plastocyanin reductase inhibitor	7	0.9391
3136	Platelet activating factor alpha antagonist	605	0.9833
3137	Platelet activating factor antagonist	2431	0.9715
3138	Platelet activating factor beta antagonist	921	0.9814
3139	Platelet adhesion inhibitor	17	0.8238
3140	Platelet aggregation inhibitor	3826	0.9100
3141	Platelet aggregation stimulant	7	0.8475
3142	Platelet antagonist	1928	0.9517
3143	Platelet derived growth factor receptor kinase inhibitor	13	0.8643
3144	Platelet growth factor antagonist	756	0.9866
3145	Platelet growth factor beta antagonist	186	0.9928
3146	Plus-end-directed kinesin ATPase inhibitor	3	0.9867
3147	Pneumotoxic	17	0.9551
3148	Polar-amino-acid-transporting ATPase inhibitor	4	0.9662
3149	Polarisation inhibitor	41	0.9362
3150	Polarisation stimulant	9	0.9084
3151	Polo-like kinase inhibitor	295	0.9758
3152	Polo-like kinase-1 inhibitor	214	0.9772
3153	Poly(3-hydroxybutyrate) depolymerase inhibitor	13	0.9877
3154	Poly(ADP-ribose) glycohydrolase inhibitor	19	0.9748
3155	Poly(ADP-ribose) polymerase 1 inhibitor	622	0.9950
3156	Poly(ADP-ribose) polymerase 2 inhibitor	53	0.9887
3157	Poly(ADP-ribose) polymerase inhibitor	1241	0.9894
3158	Poly(alpha-L-guluronate) lyase inhibitor	5	0.9793
3159	Poly(beta-D-mannuronate) lyase inhibitor	4	0.9679
3160	Polyamine biosynthesis inhibitor	18	0.9913
3161	Polyamine oxidase inhibitor	14	0.9568
3162	Polyamine-transporting ATPase inhibitor	3	0.9530
3163	Polygalacturonase inhibitor	6	0.9672
3164	Polyneuridine-aldehyde esterase inhibitor	3	0.9876
3165	Polynucleotide 5'-hydroxy-kinase inhibitor	15	0.9194
3166	Polynucleotide adenylyltransferase inhibitor	27	0.9472
3167	Polypeptide N-acetylgalactosaminyltransferase inhibitor	16	0.9884
3168	Polyphosphate kinase inhibitor	4	0.9953
3169	Polyphosphate-glucose phosphotransferase inhibitor	5	0.9996
3170	Polyporopepsin inhibitor	6	0.8342
3171	Polyribonucleotide nucleotidyltransferase inhibitor	9	0.9054
3172	Porphobilinogen synthase inhibitor	22	0.9855
3173	Porphyria	28	0.8727
3174	Postcoital contraceptive	42	0.9905
3175	Postmenopausal disorders treatment	242	0.9815
3176	Postsynaptic density protein 95 inhibitor	3	1.0000
3177	Posttraumatic stress disorder treatment	30	0.9443
3178	Postural (orthostatic) hypotension	27	0.8790
3179	Potassium channel (ATP-sensitive) activator	172	0.9797
3180	Potassium channel (ATP-sensitive) blocker	239	0.9884
3181	Potassium channel (Ca-activated) activator	186	0.9716
3182	Potassium channel (Ca-activated) blocker	261	0.9835
3183	Potassium channel (Inward rectifier) 1 blocker	80	0.9983
3184	Potassium channel (Inward rectifier) 11 blocker	86	0.9937
3185	Potassium channel (Inward rectifier) activator	172	0.9797
3186	Potassium channel (Inward rectifier) blocker	394	0.9897
3187	Potassium channel (Voltage-sensitive) activator	162	0.9916
3188	Potassium channel (Voltage-sensitive) blocker	2102	0.9549
3189	Potassium channel activator	1430	0.9809
3190	Potassium channel blocker	3131	0.9498
3191	Potassium channel intermediate-conductance Ca-activated 4 blocker	34	1.0000
3192	Potassium channel intermediate-conductance Ca-activated activator	4	0.9869
3193	Potassium channel intermediate-conductance Ca-activated blocker	66	0.9891
3194	Potassium channel KCNQ activator	162	0.9916
3195	Potassium channel KCNQ blocker	8	0.9973
3196	Potassium channel KCNQ2 activator	45	0.9998
3197	Potassium channel KCNQ3 activator	6	0.9829
3198	Potassium channel Kv1.1 blocker	135	0.9826
3199	Potassium channel Kv1.3 blocker	245	0.9894
3200	Potassium channel Kv1.5 blocker	444	0.9829
3201	Potassium channel Kv4.3 blocker	82	0.9785
3202	Potassium channel large-conductance Ca-activated activator	161	0.9808
3203	Potassium channel small-conductance Ca-activated 3 activator	6	0.9900
3204	Potassium channel small-conductance Ca-activated 3 blocker	42	0.9997
3205	Potassium channel small-conductance Ca-activated activator	9	0.9990
3206	Potassium channel small-conductance Ca-activated blocker	125	0.9966
3207	Pregnane X receptor agonist	13	0.9471
3208	Pregnane X receptor antagonist	35	0.9873
3209	Premature ejaculation treatment	112	0.9794
3210	Premenstrual syndrome treatment	26	0.9567
3211	Preneoplastic conditions treatment	8	0.8643
3212	Prenyl-diphosphatase inhibitor	5	0.9747
3213	Prephenate dehydratase inhibitor	23	0.9938
3214	Prephenate dehydrogenase inhibitor	20	0.9501
3215	Prepilin peptidase inhibitor	3	0.9948
3216	Preterm labor treatment	87	0.9747
3217	Prion diseases treatment	31	0.8309
3218	PRL phosphatase inhibitor	28	0.9609
3219	Procollagen C-endopeptidase inhibitor	17	0.9658
3220	Procollagen galactosyltransferase inhibitor	13	0.9974
3221	Procollagen glucosyltransferase inhibitor	13	0.9942
3222	Procollagen N-endopeptidase inhibitor	7	0.9729
3223	Procollagen-lysine 5-dioxygenase inhibitor	21	0.9629
3224	Procollagen-proline 3-dioxygenase inhibitor	14	0.9999
3225	Progesterone agonist	173	0.9925
3226	Progesterone antagonist	1088	0.9961
3227	Progesterone receptor A antagonist	98	0.9997
3228	Progesterone receptor B antagonist	66	0.9990
3229	Progesterone receptor B1 antagonist	24	0.9999
3230	Prokinetic	512	0.9798
3231	Prokineticin receptor 1 antagonist	3	1.0000
3232	Prolactin inhibitor	43	0.9680
3233	Prolactin release inhibitor	63	0.9878
3234	Proliferative diseases treatment	207	0.9141
3235	Proline dehydrogenase inhibitor	4	0.9981
3236	Proline racemase inhibitor	17	0.9942
3237	Proline transporter inhibitor	23	1.0000
3238	Prolyl aminopeptidase inhibitor	13	0.9376
3239	Prolyl endopeptidase inhibitor	354	0.9865
3240	Pro-opiomelanocortin converting enzyme inhibitor	5	0.9402
3241	Propanediol dehydratase inhibitor	17	0.9940
3242	Propionate CoA-transferase inhibitor	4	0.9992
3243	Propionate-CoA ligase inhibitor	7	0.9940
3244	Prostacyclin agonist	62	0.9844
3245	Prostacyclin antagonist	138	0.9948
3246	Prostaglandin A1 agonist	3	1.0000
3247	Prostaglandin agonist	324	0.9900
3248	Prostaglandin antagonist	1739	0.9870
3249	Prostaglandin D2 agonist	9	0.9769
3250	Prostaglandin D2 antagonist	564	0.9978
3251	Prostaglandin E1 agonist	20	0.9995
3252	Prostaglandin E1 antagonist	4	0.9555
3253	Prostaglandin E2 agonist	120	0.9963
3254	Prostaglandin E2 antagonist	717	0.9869
3255	Prostaglandin EP1 antagonist	127	0.9978
3256	Prostaglandin EP12 antagonist	50	0.9996
3257	Prostaglandin EP2 agonist	38	0.9996
3258	Prostaglandin EP2 antagonist	173	0.9984
3259	Prostaglandin EP3 antagonist	471	0.9976
3260	Prostaglandin EP4 agonist	70	1.0000
3261	Prostaglandin EP4 antagonist	290	0.9983
3262	Prostaglandin F2 alpha agonist	26	0.9997
3263	Prostaglandin F2 alpha antagonist	48	0.9811
3264	Prostaglandin H2 antagonist	379	0.9981
3265	Prostaglandin-A1 DELTA-isomerase inhibitor	4	0.9251
3266	Prostaglandin-E synthase inhibitor	158	0.9971
3267	Prostaglandin-E2 9-reductase inhibitor	15	0.8922
3268	Prostaglandin-E2 synthase 1 inhibitor	32	0.9957
3269	Prostaglandin-I synthase inhibitor	42	0.9886
3270	Prostate cancer treatment	2865	0.9315
3271	Prostate disorders treatment	394	0.8980
3272	Prostatic (benign) hyperplasia treatment	1874	0.9665
3273	Protease (Human cytomegalovirus) inhibitor	149	0.9994
3274	Protease 3C (Human rhinovirus) inhibitor	177	0.9933
3275	Protease activated receptor 1 antagonist	145	0.9902
3276	Protease activated receptor antagonist	161	0.9792
3277	Protease inhibitor	513	0.9506
3278	Proteasome ATPase inhibitor	3	0.9027
3279	Proteasome endopeptidase complex inhibitor	32	0.9662
3280	Proteasome inhibitor	133	0.9635
3281	Protein 30S ribosomal subunit inhibitor	63	0.9738
3282	Protein 50S ribosomal subunit inhibitor	108	0.9878
3283	Protein C (activated) inhibitor	14	0.9913
3284	Protein glycation inhibitor	4	1.0000
3285	Protein kinase (CaMK, MLCK, PhK, SNF, KIN, NIM1, MAPKAP, POLO, CHK, ULK, RSK-2nd domain) inhibitor	567	0.9893
3286	Protein kinase (CK1) delta inhibitor	45	0.9643
3287	Protein kinase (CK1) epsilon inhibitor	21	0.9533
3288	Protein kinase (CK1) inhibitor	60	0.9366
3289	Protein kinase (CK2) inhibitor	97	0.9616
3290	Protein kinase (Mos, Mil/Raf, MEKK, RIPK, TESK, LIMK, IRAK, ILK, Activin/TGF-beta) inhibitor	690	0.9837
3291	Protein kinase (PKA, PKC, AKT, GRK, AGC-related, RSK, DBF2, SGK) inhibitor	92	0.9667
3292	Protein kinase A inhibitor	438	0.9859
3293	Protein kinase B alpha inhibitor	42	0.9486
3294	Protein kinase B beta inhibitor	258	0.9846
3295	Protein kinase B gamma inhibitor	120	0.9685
3296	Protein kinase B inhibitor	721	0.9748
3297	Protein kinase B stimulant	27	0.9510
3298	Protein kinase C alpha inhibitor	602	0.9879
3299	Protein kinase C beta I inhibitor	68	0.9993
3300	Protein kinase C beta II inhibitor	85	0.9997
3301	Protein kinase C beta inhibitor	463	0.9824
3302	Protein kinase C delta inhibitor	560	0.9885
3303	Protein kinase C epsilon inhibitor	397	0.9841
3304	Protein kinase C eta inhibitor	346	0.9820
3305	Protein kinase C gamma inhibitor	372	0.9894
3306	Protein kinase C inhibitor	1355	0.9726
3307	Protein kinase C mu inhibitor	144	0.9856
3308	Protein kinase C nu inhibitor	135	0.9836
3309	Protein kinase C stimulant	61	0.9882
3310	Protein kinase C theta inhibitor	379	0.9875
3311	Protein kinase C zeta inhibitor	177	0.9935
3312	Protein kinase inhibitor	14972	0.9373
3313	Protein kinase stimulant	101	0.9450
3314	Protein N-acetylglucosaminyltransferase inhibitor	8	0.9952
3315	Protein phosphatase 2A inhibitor	50	0.9987
3316	Protein phosphatase inhibitor	1971	0.9642
3317	Protein synthesis inhibitor	356	0.9422
3318	Protein synthesis stimulant	9	0.9627
3319	Protein-arginine deiminase inhibitor	7	0.9277
3320	Protein-arginine N-methyltransferase inhibitor	6	1.0000
3321	Protein-disulfide reductase (glutathione) inhibitor	11	0.8021
3322	Protein-glucosylgalactosylhydroxylysine glucosidase inhibitor	3	0.9918
3323	Protein-glutamate methylesterase inhibitor	13	0.9618
3324	Protein-glutamate O-methyltransferase inhibitor	4	0.9888
3325	Protein-L-isoaspartate (D-aspartate) O-methyltransferase inhibitor	3	0.9998
3326	Protein-Npi-phosphohistidine-sugar phosphotransferase inhibitor	12	0.9600
3327	Protein-serine-threonine kinase inhibitor	2400	0.9610
3328	Protein-S-isoprenylcysteine O-methyltransferase inhibitor	26	0.9706
3329	Protein-synthesizing GTPase inhibitor	15	0.9005
3330	Protein-tyrosine kinase (PTK, not ETK, WZC) inhibitor	607	0.9695
3331	Protein-tyrosine kinase Lyn inhibitor	204	0.9598
3332	Protein-tyrosine kinase p55(blk) inhibitor	33	0.9245
3333	Protein-tyrosine phosphatase 1B inhibitor	1185	0.9823
3334	Protein-tyrosine phosphatase 2C inhibitor	59	0.9701
3335	Protein-tyrosine phosphatase beta inhibitor	11	0.9983
3336	Protein-tyrosine phosphatase C inhibitor	4	1.0000
3337	Protein-tyrosine phosphatase epsilon inhibitor	5	1.0000
3338	Protein-tyrosine phosphatase inhibitor	1813	0.9687
3339	Protein-tyrosine phosphatase mu inhibitor	4	0.9998
3340	Protein-tyrosine phosphatase yopH inhibitor	9	0.9908
3341	Protein-tyrosine sulfotransferase inhibitor	10	0.9789
3342	Protocatechuate 3,4-dioxygenase inhibitor	28	0.9933
3343	Protocatechuate 4,5-dioxygenase inhibitor	11	0.9995
3344	Protocollagen prolyl hydroxylase inhibitor	105	0.9837
3345	Proto-oncogene tyrosine-protein kinase c-hck inhibitor	257	0.9945
3346	Proto-oncogene tyrosine-protein kinase Fgr inhibitor	14	0.9047
3347	Proto-oncogene tyrosine-protein kinase Fyn inhibitor	84	0.9384
3348	Proto-oncogene tyrosine-protein kinase Kit inhibitor	386	0.9782
3349	Proto-oncogene tyrosine-protein kinase Yes inhibitor	42	0.9291
3350	Prunasin beta-glucosidase inhibitor	6	0.9729
3351	Pseudolysin inhibitor	4	0.8089
3352	Pseudoporphyria	7	0.8393
3353	Pseudouridylate synthase inhibitor	4	0.9763
3354	Psychomotor impairment	34	0.8232
3355	Psychoses	62	0.8137
3356	Psychosexual dysfunction treatment	61	0.9444
3357	Pteridine reductase inhibitor	9	0.9787
3358	Pterin deaminase inhibitor	4	0.9314
3359	Pullulanase inhibitor	7	0.9503
3360	Pulmonary edema	94	0.8605
3361	Pulmonary hypertension treatment	133	0.8936
3362	Pure red cell aplasia	9	0.8919
3363	Purine antagonist	21	0.9987
3364	Purine biosynthesis inhibitor	14	0.9935
3365	Purine nucleosidase inhibitor	26	0.9967
3366	Purine nucleoside phosphorylase inhibitor	232	0.9969
3367	Purinergic P2 agonist	17	0.9768
3368	Purinergic P2 antagonist	864	0.9803
3369	Purinergic P2T antagonist	74	0.9809
3370	Purinergic P2X agonist	6	0.9994
3371	Purinergic P2X antagonist	525	0.9867
3372	Purinergic P2X1 antagonist	15	0.9391
3373	Purinergic P2X2 antagonist	41	0.9891
3374	Purinergic P2X3 antagonist	53	0.9762
3375	Purinergic P2X4 antagonist	14	0.9980
3376	Purinergic P2X7 antagonist	452	0.9945
3377	Purinergic P2Y agonist	7	0.9516
3378	Purinergic P2Y antagonist	274	0.9820
3379	Purinergic P2Y1 antagonist	75	0.9731
3380	Purinergic P2Y12 antagonist	178	0.9855
3381	Purinergic receptor agonist	17	0.9768
3382	Purinergic receptor antagonist	906	0.9772
3383	Puromycin-sensitive aminopeptidase inhibitor	4	1.0000
3384	Putrescine carbamoyltransferase inhibitor	6	0.9988
3385	Putrescine oxidase inhibitor	14	0.9853
3386	Pyridoxal 4-dehydrogenase inhibitor	9	0.9998
3387	Pyridoxal kinase inhibitor	45	0.9637
3388	Pyridoxamine-oxaloacetate transaminase inhibitor	13	0.9984
3389	Pyridoxamine-phosphate oxidase inhibitor	9	0.9968
3390	Pyridoxamine-pyruvate transaminase inhibitor	4	0.9997
3391	Pyridoxine 4-oxidase inhibitor	3	0.9790
3392	Pyridoxine 5-dehydrogenase inhibitor	6	0.9921
3393	Pyrimidine antagonist	41	0.9827
3394	Pyrimidine-deoxynucleoside 2'-dioxygenase inhibitor	6	0.9911
3395	Pyroglutamyl-peptidase I inhibitor	40	0.9537
3396	Pyroglutamyl-peptidase II inhibitor	14	0.8603
3397	Pyrroline-5-carboxylate reductase inhibitor	17	0.9902
3398	Pyruvate carboxylase inhibitor	27	0.9358
3399	Pyruvate decarboxylase inhibitor	7	0.9325
3400	Pyruvate dehydrogenase (cytochrome) inhibitor	4	0.9885
3401	Pyruvate dehydrogenase (lipoamide) inhibitor	22	0.9776
3402	Pyruvate dehydrogenase inhibitor	25	0.9529
3403	Pyruvate dehydrogenase kinase inhibitor	192	0.9722
3404	Pyruvate dehydrogenase stimulant	48	0.9986
3405	Pyruvate kinase inhibitor	38	0.9725
3406	Pyruvate synthase inhibitor	5	0.9994
3407	Pyruvate, phosphate dikinase inhibitor	21	0.9922
3408	Pyruvate, water dikinase inhibitor	10	0.9946
3409	QT interval prolongation	117	0.8617
3410	Quercetin 2,3-dioxygenase inhibitor	11	0.9829
3411	Queuine tRNA-ribosyltransferase inhibitor	37	0.9961
3412	Quinate 5-dehydrogenase inhibitor	4	0.9994
3413	Quinoline-4-carboxylate 2-oxidoreductase inhibitor	4	0.9785
3414	Quinoprotein glucose dehydrogenase inhibitor	4	0.9726
3415	Quisqualate antagonist	4	0.9557
3416	Radical formation agonist	28	0.9597
3417	Radioprotector	246	0.8950
3418	Radiosensitizer	183	0.8517
3419	Raf kinase B inhibitor	280	0.9891
3420	Raf kinase C inhibitor	93	0.9770
3421	Raf kinase inhibitor	665	0.9839
3422	RAS guanyl releasing protein antagonist	4	1.0000
3423	Raynaud's phenomenon treatment	11	0.8713
3424	Reductant	62	0.9113
3425	Reductase inhibitor	4	0.9057
3426	RELA expression inhibitor	14	0.8559
3427	Releasing hormone agonist	23	0.9442
3428	Renal disease treatment	1001	0.9383
3429	Renal failure treatment	489	0.9468
3430	Renal tissue kallikrein inhibitor	14	0.9141
3431	Renilla-luciferin 2-monooxygenase inhibitor	12	0.9891
3432	Renin inhibitor	1609	0.9931
3433	Replication protein E1 (HPV) antagonist	3	1.0000
3434	Reproductive dysfunction	219	0.7925
3435	Respiratory analeptic	175	0.8796
3436	Respiratory distress syndrome treatment	321	0.9097
3437	Respiratory failure	323	0.8336
3438	Respiratory impairment	35	0.8073
3439	Restenosis treatment	784	0.9404
3440	Restless leg syndrome treatment	21	0.9452
3441	RET inhibitor	81	0.9335
3442	Retinal dehydrogenase inhibitor	7	0.9047
3443	Retinoic acid alpha receptor agonist	27	0.9973
3444	Retinoic acid alpha receptor antagonist	243	0.9988
3445	Retinoic acid beta receptor agonist	15	0.9925
3446	Retinoic acid beta receptor antagonist	249	0.9995
3447	Retinoic acid metabolism inhibitor	8	0.9139
3448	Retinoic acid receptor agonist	147	0.9944
3449	Retinoic acid receptor antagonist	383	0.9975
3450	Retinoic acid receptor gamma antagonist	278	0.9966
3451	Retinoid X alpha receptor agonist	23	0.9952
3452	Retinoid X alpha receptor antagonist	212	0.9998
3453	Retinoid X beta receptor antagonist	58	0.9996
3454	Retinoid X gamma receptor antagonist	63	0.9997
3455	Retinoid X receptor agonist	110	0.9980
3456	Retinoid X receptor antagonist	221	0.9998
3457	Retinol dehydrogenase inhibitor	6	0.9662
3458	Retinol O-fatty-acyltransferase inhibitor	7	0.9944
3459	Retinopathy treatment	22	0.9208
3460	Retinoprotector	21	0.8230
3461	Retinyl-palmitate esterase inhibitor	18	0.9816
3462	Retroperitoneal fibrosis	9	0.8101
3463	Reverse transcriptase (Hepatitis B) inhibitor	36	1.0000
3464	Rhamnulose-1-phosphate aldolase inhibitor	7	0.9757
3465	Rheumatoid arthritis treatment	1677	0.9074
3466	Rhinitis treatment	284	0.8633
3467	Rhizopuspepsin inhibitor	4	0.9403
3468	Rho-associated kinase I inhibitor	76	0.9780
3469	Rho-associated kinase II inhibitor	230	0.9897
3470	Rho-associated kinase inhibitor	341	0.9897
3471	Rhodesain inhibitor	78	0.9967
3472	Rhodopsin kinase inhibitor	34	0.9410
3473	Rhodotorulapepsin inhibitor	9	0.9677
3474	Ribitol 2-dehydrogenase inhibitor	6	0.9953
3475	Riboflavin kinase inhibitor	24	0.9974
3476	Riboflavin phosphotransferase inhibitor	4	0.9893
3477	Riboflavin synthase inhibitor	12	0.9988
3478	Ribonuclease inhibitor	48	0.9494
3479	Ribonuclease L inhibitor	9	1.0000
3480	Ribonuclease T2 inhibitor	26	0.9989
3481	Ribonuclease U2 inhibitor	5	0.9894
3482	Ribonucleoside diphosphate reductase inhibitor	93	0.9814
3483	Ribonucleoside triphosphate reductase inhibitor	17	0.8985
3484	Ribonucleotide reductase inhibitor	199	0.9860
3485	Ribose-5-phosphate adenylyltransferase inhibitor	7	0.9912
3486	Ribose-5-phosphate isomerase inhibitor	21	0.9919
3487	Ribose-5-phosphate-ammonia ligase inhibitor	7	0.9871
3488	Ribose-phosphate diphosphokinase inhibitor	38	0.9933
3489	Ribosomal protein S6 kinase 1, 70-kDa inhibitor	64	0.9633
3490	Ribosomal protein S6 kinase inhibitor	121	0.9707
3491	Ribosomal protein S6 kinase, 70-kDa inhibitor	98	0.9568
3492	Ribosomal protein S6 kinase, 90kD, polypeptide 5 inhibitor	4	1.0000
3493	Ribosomal protein S6 kinase, 90-kDa inhibitor	42	0.9624
3494	Ribosylpyrimidine nucleosidase inhibitor	9	0.9981
3495	Ribulose-bisphosphate carboxylase inhibitor	15	0.9869
3496	Ribulose-phosphate 3-epimerase inhibitor	3	0.8606
3497	RNA agonist	3	0.9993
3498	RNA directed DNA polymerase inhibitor	129	0.9089
3499	RNA ligase (ATP) inhibitor	15	0.9999
3500	RNA synthesis inhibitor	106	0.8979
3501	RNA-directed RNA polymerase (Influenza A) inhibitor	13	0.9998
3502	RNA-directed RNA polymerase inhibitor	26	0.8614
3503	RNA-directed RNA polymerase stimulant	7	0.9984
3504	Rotamase (FKBP) inhibitor	6	0.9968
3505	Rotamase (FKBP12) inhibitor	77	0.9932
3506	rRNA (adenosine-2'-O-)-methyltransferase inhibitor	12	0.9985
3507	Rubefacient	7	0.9703
3508	Rubredoxin-NAD+ reductase inhibitor	14	0.8197
3509	Ryanodine receptor 1 antagonist	7	0.9934
3510	Ryanodine receptor antagonist	7	0.9934
3511	Saccharolysin inhibitor	4	0.9865
3512	Saccharopepsin inhibitor	3	0.8770
3513	Saccharopine dehydrogenase (NAD+, L-glutamate-forming) inhibitor	4	0.9930
3514	Saccharopine dehydrogenase (NAD+, L-lysine-forming) inhibitor	19	0.9790
3515	Saccharopine dehydrogenase (NADP+, L-glutamate-forming) inhibitor	5	0.9905
3516	Saccharopine dehydrogenase (NADP+, L-lysine-forming) inhibitor	12	0.9948
3517	S-adenosyl-L-homocysteine hydrolase inhibitor	69	0.9997
3518	S-adenosyl-L-methionine decarboxylase inhibitor	58	0.9985
3519	Salicylate 1-monooxygenase inhibitor	6	0.9660
3520	S-alkylcysteine lyase inhibitor	3	0.9744
3521	Saluretic	95	0.9280
3522	Saponin-like	8	1.0000
3523	Sarcopenia treatment	25	0.9786
3524	Sarcosine oxidase inhibitor	14	0.9850
3525	Sclerosant	4	0.9424
3526	Scyllo-inosamine-4-phosphate amidinotransferase inhibitor	4	0.9939
3527	Scytalone dehydratase inhibitor	21	0.9915
3528	Secretase alpha stimulant	11	0.8479
3529	Secretase beta 1 inhibitor	754	0.9906
3530	Secretase beta 2 inhibitor	296	0.9965
3531	Secretase beta inhibitor	956	0.9898
3532	Secretase gamma inhibitor	415	0.9981
3533	Secretase inhibitor	1367	0.9875
3534	Secretase stimulant	11	0.8479
3535	Secretory phospholipase A2 inhibitor	151	0.9888
3536	Sedative	1223	0.9176
3537	Sedoheptulose-bisphosphatase inhibitor	7	0.9545
3538	Selectin antagonist	219	0.9854
3539	Selectin E antagonist	147	0.9817
3540	Selectin L antagonist	30	0.9993
3541	Selectin P antagonist	65	0.9984
3542	Selenide, water dikinase inhibitor	4	0.9998
3543	Selenocysteine lyase inhibitor	3	0.9895
3544	Sensitization	161	0.9250
3545	Sensory disturbance	800	0.8177
3546	Sepiapterin deaminase inhibitor	12	0.9969
3547	Sepiapterin reductase inhibitor	46	0.9573
3548	Sepsis treatment	154	0.9339
3549	Septic shock treatment	922	0.9211
3550	Serine 3-dehydrogenase inhibitor	6	0.9891
3551	Serine carboxypeptidase inhibitor	38	0.9800
3552	Serine O-acetyltransferase inhibitor	15	0.9593
3553	Serine protease unspecified inhibitor	22	0.9419
3554	Serine-glyoxylate transaminase inhibitor	12	0.9938
3555	Serine-phosphoethanolamine synthase inhibitor	10	0.9869
3556	Serine-pyruvate transaminase inhibitor	4	0.9833
3557	Serine-sulfate ammonia-lyase inhibitor	30	0.9955
3558	Serine-tRNA ligase inhibitor	6	0.9905
3559	Serine-type D-Ala-D-Ala carboxypeptidase inhibitor	36	0.9954
3560	Serralysin inhibitor	22	0.9629
3561	Serratia marcescens nuclease inhibitor	7	0.9708
3562	Serum-glucocorticoid regulated kinase 1 inhibitor	24	0.8755
3563	Serum-glucocorticoid regulated kinase inhibitor	52	0.9333
3564	Severe acute respiratory syndrome treatment	29	0.9270
3565	S-formylglutathione hydrolase inhibitor	8	0.8870
3566	Shab potassium channel blocker	4	0.8520
3567	Shaker potassium channel blocker	824	0.9843
3568	Shal potassium channel blocker	82	0.9785
3569	Shikimate 5-dehydrogenase inhibitor	6	0.9840
3570	Shikimate kinase inhibitor	22	0.9718
3571	Shikimate O-hydroxycinnamoyltransferase inhibitor	4	0.9751
3572	Shivering	6	0.8362
3573	Shock treatment	55	0.9752
3574	Sialorrhea	22	0.8348
3575	Sickle-cell anemia treatment	54	0.9236
3576	Sigma 1 receptor agonist	14	0.9656
3577	Sigma 1 receptor antagonist	1058	0.9949
3578	Sigma 2 receptor antagonist	585	0.9958
3579	Sigma 3 receptor antagonist	11	0.9999
3580	Sigma receptor agonist	23	0.9321
3581	Sigma receptor antagonist	2161	0.9874
3582	Signal peptidase I inhibitor	12	0.9697
3583	Signal peptidase IB inhibitor	3	1.0000
3584	Signal transduction pathways inhibitor	3899	0.9214
3585	Simian immunodeficiency virus proteinase inhibitor	4	0.8632
3586	Sirtuin 2 inhibitor	39	0.9968
3587	Sirtuin inhibitor	47	0.9962
3588	Site-specific DNA-methyltransferase (adenine-specific) inhibitor	4	0.9909
3589	Skeletal muscle relaxant	219	0.9180
3590	Skin irritation, corrasive	15	0.9072
3591	Skin irritation, high	405	0.9556
3592	Skin irritation, inactive	188	0.9358
3593	Skin irritation, moderate	269	0.9756
3594	Skin irritation, weak	468	0.9683
3595	Skin irritative effect	1117	0.9594
3596	Skin whitener	48	0.9748
3597	Sleep apnea treatment	79	0.9597
3598	Sleep disorders treatment	1271	0.9611
3599	Sleep disturbance	1188	0.8204
3600	Small monomeric GTPase inhibitor	3	0.9947
3601	S-methyl-5-thioadenosine phosphorylase inhibitor	47	0.9955
3602	S-methyl-5-thioribose kinase inhibitor	9	0.9913
3603	SMN2 expression enhancer	22	0.9208
3604	Smo receptor agonist	3	1.0000
3605	Smo receptor antagonist	122	0.9935
3606	Smooth muscle myosin light chain kinase inhibitor	46	0.9002
3607	Snapalysin inhibitor	4	0.9873
3608	Sneezing	56	0.8172
3609	Sodium channel (voltage-gated) blocker	537	0.9647
3610	Sodium channel blocker	1004	0.9381
3611	Sodium channel blocker class Ib	6	0.9721
3612	Sodium/bile acid cotransporter inhibitor	16	0.9703
3613	Sodium/calcium exchanger 1 inhibitor	25	0.9727
3614	Sodium/calcium exchanger inhibitor	109	0.9874
3615	Sodium/glucose cotransporter 1 inhibitor	180	0.9920
3616	Sodium/glucose cotransporter 2 inhibitor	425	0.9980
3617	Sodium/glucose cotransporter inhibitor	587	0.9940
3618	Sodium/hydrogen exchanger 1 inhibitor	296	0.9986
3619	Sodium/hydrogen exchanger 2 inhibitor	157	0.9995
3620	Sodium/hydrogen exchanger 3 inhibitor	220	0.9987
3621	Sodium/hydrogen exchanger 5 inhibitor	6	0.9956
3622	Sodium/hydrogen exchanger inhibitor	665	0.9982
3623	Sodium-dependent vitamin C transporter 2 inhibitor	3	1.0000
3624	Somatostatin 1 antagonist	219	0.9939
3625	Somatostatin 2 agonist	7	0.9875
3626	Somatostatin 2 antagonist	319	0.9936
3627	Somatostatin 3 antagonist	276	0.9943
3628	Somatostatin 4 antagonist	311	0.9941
3629	Somatostatin 5 agonist	15	0.9991
3630	Somatostatin 5 antagonist	279	0.9929
3631	Somatostatin agonist	34	0.9632
3632	Somatostatin antagonist	397	0.9922
3633	Sorbitol-6-phosphate 2-dehydrogenase inhibitor	3	0.9766
3634	Sorbose dehydrogenase inhibitor	3	0.9948
3635	Spasmolytic	1457	0.9068
3636	Spasmolytic, Papaverin-like	188	0.9330
3637	Spasmolytic, urinary	24	0.8539
3638	Spermicide	54	0.8635
3639	Spermidine dehydrogenase inhibitor	5	0.8197
3640	Spermidine synthase inhibitor	36	0.9952
3641	Spermine antagonist	3	0.9997
3642	Spermine synthase inhibitor	23	0.9953
3643	Sphinganine kinase inhibitor	6	0.8230
3644	Sphinganine-1-phosphate aldolase inhibitor	6	0.9794
3645	Sphingomyelinase inhibitor	15	0.9853
3646	Sphingosine 1-phosphate receptor 1 agonist	107	0.9996
3647	Sphingosine 1-phosphate receptor 1 antagonist	122	0.9299
3648	Sphingosine 1-phosphate receptor 3 agonist	12	1.0000
3649	Sphingosine 1-phosphate receptor 3 antagonist	157	0.9844
3650	Sphingosine 1-phosphate receptor 4 agonist	5	0.9999
3651	Sphingosine 1-phosphate receptor 4 antagonist	208	0.9473
3652	Sphingosine 1-phosphate receptor 5 agonist	5	0.8629
3653	Sphingosine 1-phosphate receptor 5 antagonist	91	0.9877
3654	Sphingosine 1-phosphate receptor agonist	108	0.9996
3655	Sphingosine 1-phosphate receptor antagonist	344	0.9481
3656	Sphingosine kinase 1 inhibitor	23	0.9988
3657	Sphingosine kinase inhibitor	32	0.9907
3658	Sphingosine kinase stimulant	3	1.0000
3659	Splenomegaly	27	0.8291
3660	Sporulation kinase A inhibitor	11	0.9942
3661	Squalene epoxidase inhibitor	71	0.9604
3662	Squalene synthetase inhibitor	504	0.9936
3663	Squalene-hopene cyclase inhibitor	35	0.9692
3664	Src kinase inhibitor	2629	0.9691
3665	Stearoyl-CoA desaturase inhibitor	299	0.9817
3666	Stem cell growth factor agonist	190	0.9716
3667	Steroid 17-alpha-hydroxylase/17,20 lyase inhibitor	365	0.9949
3668	Steroid 9alpha-monooxygenase inhibitor	3	0.9979
3669	Steroid DELTA-isomerase inhibitor	28	0.9730
3670	Steroid N-acetylglucosaminyltransferase inhibitor	4	0.9570
3671	Steroid sulfotransferase inhibitor	11	0.9268
3672	Steroid synthesis inhibitor	10	0.8688
3673	Steroid-like	18	0.9974
3674	Sterol 24-C-methyltransferase inhibitor	27	0.9851
3675	Sterol 3-beta-glucosyltransferase inhibitor	12	0.9573
3676	Stipitatonate decarboxylase inhibitor	5	0.9983
3677	Stomatitis	255	0.7835
3678	Streptogrisin A inhibitor	3	0.9996
3679	Streptomycin 6-kinase inhibitor	6	0.9968
3680	Streptopain inhibitor	13	0.9869
3681	Stroke treatment	4811	0.9224
3682	Strombine dehydrogenase inhibitor	5	0.9996
3683	Stromelysin 2 inhibitor	11	0.9019
3684	Styrene-oxide isomerase inhibitor	3	0.9865
3685	Substance P antagonist	307	0.9803
3686	Subtilisin inhibitor	27	0.9605
3687	Succinate dehydrogenase inhibitor	14	0.9573
3688	Succinate-CoA ligase (ADP-forming) inhibitor	16	0.9825
3689	Succinate-hydroxymethylglutarate CoA-transferase inhibitor	8	0.9924
3690	Succinate-semialdehyde dehydrogenase [NAD(P)+] inhibitor	7	0.8456
3691	Succinate-semialdehyde dehydrogenase inhibitor	20	0.9926
3692	Succinic dehydrogenase inhibitor	8	0.9681
3693	Sucrose alpha-glucosidase inhibitor	19	0.9960
3694	Sucrose phosphorylase inhibitor	5	0.9996
3695	Sucrose synthase inhibitor	16	0.9923
3696	Sucrose-phosphate phosphatase inhibitor	7	0.9980
3697	Sucrose-phosphate synthase inhibitor	19	0.9730
3698	Sugar-phosphatase inhibitor	3	0.9015
3699	Sulfate adenylyltransferase (ADP) inhibitor	8	0.9858
3700	Sulfate adenylyltransferase inhibitor	14	0.9831
3701	Sulfinoalanine decarboxylase inhibitor	18	0.9935
3702	Sulfite dehydrogenase inhibitor	9	0.8467
3703	Sulfite oxidase inhibitor	9	0.9377
3704	Sulfite reductase inhibitor	6	0.9703
3705	Sulfonylureas	3	0.9993
3706	Sulfotransferase substrate	183	0.9624
3707	Sulfur dioxygenase inhibitor	6	0.9869
3708	Sulfur reductase inhibitor	8	0.8660
3709	SULT1A1 substrate	42	0.9783
3710	SULT1A2 substrate	24	0.9936
3711	SULT1A3 substrate	17	0.9777
3712	SULT1E1 substrate	4	0.9859
3713	SULT2A1 substrate	9	0.9415
3714	Superoxide dismutase inhibitor	15	0.8843
3715	Sweating	107	0.8098
3716	Sweetener	24	0.9559
3717	Syk tyrosine kinase inhibitor	268	0.9754
3718	Synaptic vesicle protein SV2, levetiracetam binding site antagonist	32	1.0000
3719	Systemic lupus erythematosus treatment	124	0.8686
3720	T cell inhibitor	247	0.9533
3721	T cell receptor antagonist	17	1.0000
3722	T cell receptor gamma-delta antagonist	17	1.0000
3723	T2-induced deoxynucleotide kinase inhibitor	3	0.9999
3724	Tachycardiac	437	0.8110
3725	Tagaturonate reductase inhibitor	3	0.9946
3726	Tankyrase 2 inhibitor	5	1.0000
3727	Tankyrase inhibitor	10	0.8892
3728	Tannase inhibitor	14	0.9957
3729	Tardive dyskinesia treatment	40	0.9347
3730	Tartrate decarboxylase inhibitor	5	0.9998
3731	Tartrate dehydrogenase inhibitor	5	1.0000
3732	Taurine dehydrogenase inhibitor	7	0.8612
3733	Taurine-2-oxoglutarate transaminase inhibitor	3	0.9758
3734	Taurocyamine kinase inhibitor	3	0.9794
3735	Tauropine dehydrogenase inhibitor	8	0.9594
3736	T-cell protein-tyrosine phosphatase inhibitor	243	0.9915
3737	TEC kinase inhibitor	25	0.9745
3738	Telangiectasia	18	0.8955
3739	Telomerase inhibitor	206	0.9613
3740	Telomerase stimulant	6	1.0000
3741	Tentoxilysin inhibitor	4	0.9454
3742	Teratogen	1552	0.9052
3743	Testosterone 17beta-dehydrogenase (NADP+) inhibitor	3	0.8648
3744	Testosterone 17beta-dehydrogenase inhibitor	11	0.9698
3745	Testosterone agonist	5	0.9964
3746	Tetanus neurotoxin inhibitor	3	1.0000
3747	Tetracycline antiport transporter antagonist	36	1.0000
3748	Tetrahydroxynaphthalene reductase inhibitor	7	0.9819
3749	TGF beta receptor type I kinase inhibitor	197	0.9965
3750	TGF beta receptor type II kinase inhibitor	14	1.0000
3751	TH expression enhancer	11	0.8851
3752	Theanine hydrolase inhibitor	13	0.9991
3753	Thermitase inhibitor	12	0.9022
3754	Thermolysin inhibitor	23	0.9966
3755	Thermomycolin inhibitor	3	0.9956
3756	Thiamine pyridinylase inhibitor	5	0.8594
3757	Thiamine-phosphate diphosphorylase inhibitor	7	0.9880
3758	Thiamine-phosphate kinase inhibitor	5	0.9862
3759	Thiamine-triphosphatase inhibitor	9	0.8771
3760	Thiazolidinedione	18	0.9995
3761	Thimet oligopeptidase inhibitor	20	0.9374
3762	Thioether S-methyltransferase inhibitor	3	0.9947
3763	Thiol oxidase inhibitor	13	0.9485
3764	Thiol protease inhibitor	232	0.9279
3765	Thiol S-methyltransferase inhibitor	8	0.9809
3766	Thiol sulfotransferase inhibitor	4	0.9999
3767	Thiopurine S-methyltransferase inhibitor	17	0.9438
3768	Thioredoxin inhibitor	3	0.9190
3769	Thioredoxin reductase inhibitor	53	0.9299
3770	Thiosulfate dehydrogenase inhibitor	10	0.8789
3771	Thiosulfate sulfurtransferase inhibitor	21	0.9878
3772	Threonine aldolase inhibitor	5	0.9759
3773	Threonine ammonia-lyase inhibitor	27	0.9848
3774	Threonine synthase inhibitor	11	0.9984
3775	Threonine-tRNA ligase inhibitor	5	0.9319
3776	Thrombin inhibitor	2482	0.9799
3777	Thrombocytopenia	494	0.8163
3778	Thrombocytopoiesis inhibitor	11	0.8399
3779	Thrombolytic	143	0.9304
3780	Thrombophlebitis	146	0.8016
3781	Thrombopoietin agonist	113	0.9997
3782	Thromboxane A2 antagonist	280	0.9826
3783	Thromboxane agonist	3	0.9995
3784	Thromboxane antagonist	491	0.9752
3785	Thromboxane B2 antagonist	18	0.8416
3786	Thromboxane synthase inhibitor	900	0.9864
3787	Thromboxane synthase stimulant	3	0.9890
3788	Thymidine kinase (Herpes simplex virus 1) inhibitor	38	0.9999
3789	Thymidine kinase (Herpes simplex virus 2) inhibitor	15	1.0000
3790	Thymidine kinase 1 inhibitor	28	0.9802
3791	Thymidine kinase 2 inhibitor	25	0.9999
3792	Thymidine kinase inhibitor	192	0.9827
3793	Thymidine phosphorylase inhibitor	65	0.9939
3794	Thymidine-triphosphatase inhibitor	6	0.9989
3795	Thymidylate 5'-phosphatase inhibitor	5	0.8077
3796	Thymidylate synthase inhibitor	839	0.9932
3797	Thymine dioxygenase inhibitor	14	0.9998
3798	Thyroid hormone agonist	104	0.9862
3799	Thyroid hormone alpha 1 agonist	5	1.0000
3800	Thyroid hormone alpha 1 antagonist	12	1.0000
3801	Thyroid hormone alpha agonist	5	1.0000
3802	Thyroid hormone alpha antagonist	93	0.9998
3803	Thyroid hormone antagonist	261	0.9930
3804	Thyroid hormone beta 1 agonist	5	1.0000
3805	Thyroid hormone beta 1 antagonist	156	0.9996
3806	Thyroid hormone beta agonist	74	0.9997
3807	Thyroid hormone beta antagonist	178	0.9996
3808	Thyrotropin releasing hormone agonist	15	0.9999
3809	Thyrotropin releasing hormone antagonist	6	1.0000
3810	Thyroxine 5-deiodinase inhibitor	7	0.9462
3811	TIE antagonist	749	0.9842
3812	TIE-2 agonist	6	1.0000
3813	TIE-2 antagonist	734	0.9842
3814	TNF convertase inhibitor	1028	0.9981
3815	TNF expression inhibitor	55	0.8758
3816	Tocolytic	141	0.9779
3817	Toll-Like receptor 2 antagonist	10	0.9998
3818	Toll-Like receptor 7 agonist	86	0.9979
3819	Toll-Like receptor 8 agonist	9	1.0000
3820	Toll-Like receptor agonist	88	0.9931
3821	Toll-Like receptor antagonist	16	0.8733
3822	Topoisomerase I inhibitor	478	0.9625
3823	Topoisomerase II inhibitor	726	0.9650
3824	Torsades de pointes	90	0.8224
3825	Torticollis	28	0.8350
3826	Toxic	5112	0.8644
3827	Toxic, gastrointestinal	1362	0.8187
3828	Toxic, respiration	80	0.8211
3829	Toxic, respiratory center	15	0.9270
3830	Toxic, vascular	194	0.8349
3831	TP53 expression enhancer	99	0.8227
3832	Tpr proteinase (Porphyromonas gingivalis) inhibitor	4	0.8533
3833	Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase inhibitor	42	0.9582
3834	Trans-2-enoyl-CoA reductase (NAD+) inhibitor	4	0.9885
3835	Trans-acenaphthene-1,2-diol dehydrogenase inhibitor	5	0.8085
3836	Transactivator transcription protein inhibitor	25	0.8505
3837	Transaldolase inhibitor	5	0.9998
3838	Transcortin receptor antagonist	29	0.9997
3839	Transcription factor AP-1 inhibitor	249	0.9711
3840	Transcription factor inhibitor	1287	0.9166
3841	Transcription factor NF kappa A inhibitor	7	0.8406
3842	Transcription factor NF kappa B inhibitor	534	0.9560
3843	Transcription factor NF kappa B stimulant	7	0.8530
3844	Transcription factor rho inhibitor	7	1.0000
3845	Transcription factor STAT inhibitor	269	0.8997
3846	Transcription factor STAT3 inhibitor	234	0.9104
3847	Transcription factor STAT6 inhibitor	20	0.9849
3848	Transcription factor stimulant	7	0.8530
3849	Transforming growth factor antagonist	241	0.9858
3850	Transforming growth factor beta 1 agonist	3	0.8895
3851	Transforming growth factor beta 1 antagonist	186	0.9920
3852	Transforming growth factor beta 3 antagonist	20	0.9999
3853	Transforming growth factor beta antagonist	227	0.9895
3854	Transglutaminase 2 inhibitor	27	0.9730
3855	Transketolase inhibitor	7	0.9168
3856	Translation initiation factor IF-2 antagonist	5	0.9998
3857	Trans-octaprenyltranstransferase inhibitor	12	0.9917
3858	Trans-pentaprenyltranstransferase inhibitor	5	0.9878
3859	Transplant rejection treatment	694	0.9135
3860	Transthyretin amyloid fibril formation inhibitor	29	0.9842
3861	Trehalose-phosphatase inhibitor	3	0.9956
3862	Tremor	537	0.8349
3863	Triacetate-lactonase inhibitor	3	0.9894
3864	Trimerelysin II inhibitor	7	0.9921
3865	Trimethylamine dehydrogenase inhibitor	9	0.9323
3866	Trimethylamine-N-oxide reductase inhibitor	11	0.9902
3867	Trimethylamine-oxide aldolase inhibitor	5	0.8099
3868	Trimethyllysine dioxygenase inhibitor	7	0.9819
3869	Triose-phosphate isomerase inhibitor	23	0.9855
3870	Tripeptide aminopeptidase inhibitor	23	0.9404
3871	Tripeptidyl peptidase II inhibitor	36	0.9993
3872	Tripeptidyl-peptidase I inhibitor	22	0.9634
3873	TRKA antagonist	146	0.9826
3874	TRKB antagonist	21	0.9548
3875	tRNA (adenine-N1-)-methyltransferase inhibitor	6	0.9992
3876	tRNA (cytosine-5-)-methyltransferase inhibitor	5	0.9852
3877	tRNA (guanine-N1-)-methyltransferase inhibitor	4	0.9935
3878	tRNA (guanine-N2-)-methyltransferase inhibitor	5	0.9937
3879	tRNA (guanine-N7-)-methyltransferase inhibitor	6	0.9909
3880	tRNA (uracil-5-)-methyltransferase inhibitor	10	0.9994
3881	tRNA adenylyltransferase inhibitor	9	0.9863
3882	tRNA cytidylyltransferase inhibitor	15	0.9894
3883	tRNA methyltransferase inhibitor	22	0.9950
3884	tRNA nucleotidyltransferase inhibitor	3	0.9918
3885	tRNA-pseudouridine synthase I inhibitor	3	0.9684
3886	Tropinesterase inhibitor	3	0.8568
3887	TRPA1 agonist	10	0.9334
3888	TRPA1 antagonist	17	0.9778
3889	Trypanothione-disulfide reductase inhibitor	62	0.9610
3890	Trypsin inhibitor	1401	0.9889
3891	Tryptase 1 inhibitor	144	0.9995
3892	Tryptase inhibitor	198	0.9860
3893	Tryptophan 2,3-dioxygenase inhibitor	24	0.8809
3894	Tryptophan 2-monooxygenase inhibitor	20	0.9620
3895	Tryptophan 5 hydroxylase inhibitor	25	0.9483
3896	Tryptophan alpha,beta-oxidase inhibitor	4	0.9583
3897	Tryptophan dimethylallyltransferase inhibitor	8	0.9733
3898	Tryptophan hydroxylase 1 inhibitor	16	0.9999
3899	Tryptophan synthase inhibitor	14	0.9953
3900	Tryptophan transaminase inhibitor	4	0.9877
3901	Tryptophanamidase inhibitor	5	0.9851
3902	Tryptophan-tRNA ligase inhibitor	38	0.9898
3903	Tryptophanyl aminopeptidase inhibitor	3	0.9901
3904	TTK protein kinase inhibitor	6	0.9631
3905	Tubulin agonist	26	0.9999
3906	Tubulin antagonist	1164	0.9725
3907	Tubulin GTPase inhibitor	6	0.9967
3908	Tubulin-tyrosine ligase inhibitor	17	0.9871
3909	Tubulinyl-Tyr carboxypeptidase inhibitor	6	0.9983
3910	Tumour necrosis factor alpha antagonist	688	0.9470
3911	Tumour necrosis factor alpha release inhibitor	2422	0.9445
3912	Tumour necrosis factor antagonist	781	0.9372
3913	Twitching	7	0.8119
3914	Tyrosine 2,3-aminomutase inhibitor	6	0.9944
3915	Tyrosine 3 hydroxylase inhibitor	12	0.8836
3916	Tyrosine 3 hydroxylase stimulant	3	1.0000
3917	Tyrosine kinase inhibitor	6059	0.9491
3918	Tyrosine kinase stimulant	3	0.9559
3919	Tyrosine phenol-lyase inhibitor	20	0.9981
3920	Tyrosine transaminase inhibitor	34	0.9855
3921	Tyrosine-ester sulfotransferase inhibitor	24	0.9873
3922	Tyrosine-protein kinase EMT inhibitor	199	0.9894
3923	Tyrosine-protein kinase receptor antagonist	161	0.9831
3924	Tyrosine-protein kinase receptor FLT3 inhibitor	388	0.9821
3925	Tyrosine-protein kinase TYRO 10 inhibitor	8	0.9205
3926	Ubiquinol-cytochrome-c reductase inhibitor	10	0.8164
3927	Ubiquitin thiolesterase inhibitor	7	0.9596
3928	Ubiquitin-protein ligase inhibitor	27	0.9710
3929	UDP-3-O-acyl-N-acetylglucosamine deacetylase inhibitor	60	0.9990
3930	UDP-glucose 4-epimerase inhibitor	28	0.9721
3931	UDP-glucose 6-dehydrogenase inhibitor	8	0.9509
3932	UDP-glucose-hexose-1-phosphate uridylyltransferase inhibitor	18	0.9755
3933	UDP-glucuronate 4-epimerase inhibitor	13	0.9998
3934	UDP-glucuronate 5'-epimerase inhibitor	3	0.9997
3935	UDP-glucuronate decarboxylase inhibitor	12	0.9954
3936	UDP-glucuronosyltransferase substrate	817	0.9303
3937	UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor	20	0.9900
3938	UDP-N-acetylglucosamine 2-epimerase inhibitor	7	0.9915
3939	UDP-N-acetylglucosamine 4-epimerase inhibitor	3	0.9015
3940	UDP-N-acetylglucosamine diphosphorylase inhibitor	8	0.9931
3941	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor	11	0.9808
3942	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase inhibitor	9	0.9966
3943	UDP-N-acetylmuramate dehydrogenase inhibitor	20	0.9880
3944	UDP-N-acetylmuramate-L-alanine ligase inhibitor	18	0.9760
3945	UDP-N-acetylmuramoylalanine-D-glutamate ligase inhibitor	18	0.9877
3946	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase inhibitor	8	0.9997
3947	UDP-sugar diphosphatase inhibitor	4	0.9956
3948	UGT1A substrate	313	0.9305
3949	UGT1A1 substrate	113	0.9443
3950	UGT1A10 substrate	99	0.9457
3951	UGT1A3 substrate	118	0.9426
3952	UGT1A4 substrate	128	0.9451
3953	UGT1A5 substrate	16	0.9413
3954	UGT1A6 substrate	85	0.9291
3955	UGT1A7 substrate	61	0.9443
3956	UGT1A8 substrate	99	0.9543
3957	UGT1A9 substrate	92	0.8929
3958	UGT2B substrate	259	0.9537
3959	UGT2B1 substrate	99	0.9609
3960	UGT2B10 substrate	20	0.9092
3961	UGT2B11 substrate	37	0.9553
3962	UGT2B12 substrate	4	0.8678
3963	UGT2B15 substrate	84	0.9549
3964	UGT2B17 substrate	15	0.9269
3965	UGT2B18 substrate	6	0.9698
3966	UGT2B19 substrate	5	0.9921
3967	UGT2B20 substrate	19	0.9958
3968	UGT2B23 substrate	5	0.9921
3969	UGT2B28 substrate	8	0.9620
3970	UGT2B30 substrate	5	0.9921
3971	UGT2B4 substrate	35	0.9100
3972	UGT2B4D substrate	5	0.9921
3973	UGT2B4E substrate	5	0.9921
3974	UGT2B7 substrate	138	0.9520
3975	UGT2B7H substrate	28	0.9793
3976	UGT2B7Y substrate	28	0.9793
3977	UGT2B9 substrate	39	0.9508
3978	Ulcer, aphthous	9	0.8311
3979	Ulcer, gastric	27	0.9072
3980	Ulcer, peptic	34	0.8848
3981	Ulceration	53	0.9074
3982	Ulcerative colitis treatment	3	0.9999
3983	Undecaprenyl-diphosphatase inhibitor	5	0.9828
3984	Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase inhibitor	3	0.9560
3985	Undecaprenyl-phosphate galactose phosphotransferase inhibitor	6	0.9997
3986	Undecaprenyl-phosphate mannosyltransferase inhibitor	3	0.9480
3987	Uracil phosphoribosyltransferase inhibitor	14	0.9955
3988	Urate transporter 1 inhibitor	29	0.9790
3989	Urate-ribonucleotide phosphorylase inhibitor	12	0.9232
3990	Urease inhibitor	18	0.9250
3991	Urethanase inhibitor	10	0.8744
3992	Uric acid excretion stimulant	122	0.9431
3993	Uridine kinase inhibitor	7	0.9931
3994	Uridine nucleosidase inhibitor	15	0.9913
3995	Uridine phosphorylase inhibitor	106	0.9979
3996	Urinary incontinence treatment	1959	0.9539
3997	Urinary retention	181	0.8040
3998	Urine discoloration	9	0.9539
3999	Urocanate hydratase inhibitor	16	0.9940
4000	Urokinase inhibitor	304	0.9906
4001	Urolithiasis treatment	6	0.9001
4002	Urologic disorders treatment	2025	0.9433
4003	Uroporphyrinogen decarboxylase inhibitor	30	0.9908
4004	Uroporphyrinogen-III synthase inhibitor	9	0.9397
4005	Urotensin II agonist	26	0.9999
4006	Urotensin II antagonist	45	0.9967
4007	Urticaria treatment	8	0.9538
4008	Uterine relaxant	43	0.8611
4009	Uterine rupture	3	0.9998
4010	Uterine stimulant	33	0.9474
4011	UTP-glucose-1-phosphate uridylyltransferase inhibitor	10	0.9998
4012	Valine decarboxylase inhibitor	4	0.9903
4013	Valine dehydrogenase (NADP+) inhibitor	6	0.9949
4014	Valine-pyruvate transaminase inhibitor	3	0.9999
4015	Valine-tRNA ligase inhibitor	10	0.9784
4016	Vanilloid 1 agonist	14	0.8629
4017	Vanilloid 1 antagonist	248	0.9932
4018	Vanilloid 3 antagonist	6	1.0000
4019	Vanilloid 4 agonist	6	1.0000
4020	Vanilloid 4 antagonist	73	0.9793
4021	Vanilloid agonist	20	0.9211
4022	Vanilloid antagonist	1066	0.9925
4023	Vanillyl-alcohol oxidase inhibitor	7	0.9951
4024	Vascular (periferal) disease treatment	799	0.9113
4025	Vascular adhesion protein 1 inhibitor	11	0.9012
4026	Vascular dementia treatment	10	0.8839
4027	Vascular endothelial growth factor 1 antagonist	593	0.9734
4028	Vascular endothelial growth factor 2 antagonist	3219	0.9793
4029	Vascular endothelial growth factor 3 antagonist	361	0.9760
4030	Vascular endothelial growth factor antagonist	3913	0.9709
4031	Vasculitis treatment	26	0.9529
4032	Vasodilator	1105	0.8928
4033	Vasodilator, coronary	220	0.8584
4034	Vasodilator, peripheral	190	0.8519
4035	Vasopressin 1 agonist	17	1.0000
4036	Vasopressin 1 antagonist	951	0.9955
4037	Vasopressin 1A agonist	9	1.0000
4038	Vasopressin 1A antagonist	847	0.9968
4039	Vasopressin 1B agonist	8	1.0000
4040	Vasopressin 1B antagonist	292	0.9976
4041	Vasopressin 2 agonist	132	0.9986
4042	Vasopressin 2 antagonist	748	0.9976
4043	Vasopressor	124	0.8674
4044	Vasoprotector	22	0.8107
4045	VCAM antagonist	414	0.9894
4046	VCAM-1 antagonist	413	0.9894
4047	VCAM1 expression inhibitor	56	0.9502
4048	VEGF expression inhibitor	38	0.9414
4049	VEGFR2 expression inhibitor	5	1.0000
4050	Venom exonuclease inhibitor	8	0.8720
4051	Venombin A inhibitor	9	0.9829
4052	Venombin AB inhibitor	5	0.8818
4053	Vesicant	6	0.9937
4054	Vesicle monoamine transporter 2 inhibitor	13	1.0000
4055	Vesicle monoamine transporter inhibitor	14	0.9955
4056	Vesicular acetylcholine transporter inhibitor	75	0.9984
4057	Vesicular glutamate transport inhibitor	4	1.0000
4058	Vestibular dysfunction	10	0.9202
4059	Vibriolysin inhibitor	12	0.9987
4060	Viral entry inhibitor	66	0.8665
4061	Viral fusion inhibitor	3	1.0000
4062	Visual acuity impairment	6	0.8920
4063	Vitamin	102	0.9817
4064	Vitamin D receptor agonist	102	0.9996
4065	Vitamin D receptor antagonist	75	0.9998
4066	Vitamin D3 hydroxylase inhibitor	15	0.9992
4067	Vitamin D-like	16	0.9995
4068	Vitamin K-like	19	0.9995
4069	Vitamin-K-epoxide reductase (warfarin-insensitive) inhibitor	7	0.9471
4070	Vitronectin receptor antagonist	1721	0.9968
4071	VLA-4 antagonist	1119	0.9958
4072	Vomilenine glucosyltransferase inhibitor	6	0.9833
4073	Weakness	250	0.8054
4074	Wee-1 tyrosine kinase inhibitor	5	0.9985
4075	Weight gain	25	0.8546
4076	Weight loss	169	0.8296
4077	Withdrawal	13	0.8280
4078	Wound healing agent	282	0.9068
4079	Xaa-Pro dipeptidyl-peptidase inhibitor	11	0.9837
4080	Xanthine dehydrogenase inhibitor	93	0.9798
4081	Xanthine oxidase inhibitor	110	0.9576
4082	Xanthine oxidase substrate	42	0.9765
4083	Xanthine phosphoribosyltransferase inhibitor	39	0.9971
4084	Xanthine-like	23	0.9986
4085	Xanthommatin reductase inhibitor	5	0.9853
4086	Xenobiotic-transporting ATPase inhibitor	13	0.9191
4087	Xerostomia	405	0.8001
4088	X-His dipeptidase inhibitor	22	0.9765
4089	X-methyl-His dipeptidase inhibitor	10	0.8782
4090	X-Pro dipeptidase inhibitor	21	0.9855
4091	X-Trp aminopeptidase inhibitor	7	0.9944
4092	Xylan 1,4-beta-xylosidase inhibitor	14	0.9935
4093	Xylan endo-1,3-beta-xylosidase inhibitor	5	0.9716
4094	Xylose isomerase inhibitor	11	0.9872
4095	YAK3 inhibitor	15	0.9999
4096	Yawning	39	0.8661
4097	Yeast ribonuclease inhibitor	3	0.9616
4098	ZAP-70 protein tyrosine kinase inhibitor	104	0.9823
4099	Zinc deficiency	4	0.9747