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Type:
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Approved drug |
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PubChem:
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5282192
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DrugBank:
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DB11998
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IUPAC:
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5-[(E)-2-bromoethenyl]-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]pyrimidine-2,4-dione |
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Standard InChI:
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InChI=1S/C11H13BrN2O6/c12-2-1-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h1-3,6-8,10,15-17H,4H2,(H,13,18,19)/b2-1+/t6-,7-,8+,10-/m1/s1 |
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Standard InChIKey:
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GCQYYIHYQMVWLT-HQNLTJAPSA-N |
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SMILES:
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O=C1[NH]C(=O)N(C2OC(CO)C(O)C2O)C=C1C=CBr |
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Metabolism-related information:
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(E)-5-(2-bromovinyl)uracil can inactivate a key liver enzyme, leadingto lethal toxicity of 5-fluorouracil when coadministered with 5-fluorouracil
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Reference:
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10.1517/17425255.2016.1121234 |
