HGMMX

Shikonin

Type: Dietary supplement
PubChem: 479503
DrugBank: None
IUPAC: 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione
Standard InChI: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1
Standard InChIKey: NEZONWMXZKDMKF-SNVBAGLBSA-N
SMILES: CC(C)=CCC(O)C1=CC(=O)C2=C(O)C=CC(O)=C2C1=O
Metabolism-related information: Decrease toxicity
Reference: Min B. S. et al. Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria //Journal of microbiology and biotechnology. – 2000. – Т. 10. – №. 4. – С. 514-517.

Metabolites

Chemical Structure Metablite's name Reaction name Genus Species Reference
DeoxyshikoninReductionGut microbiotaGut microbiota10.1016/S0040-4020(01)81108-X
DeoxyshikoninReductionBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.
shikometabolin ACondensationBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.
shikometabolin BCondensationBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.
shikometabolin CCondensationBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.
shikometabolin DCondensationBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.
anhydroalkanninDehydroxylationBacteroidesUnknownMin, B. S., Meselhy, M. R., Hattori, M., Kim, H. M., & Kim, Y. H. (2000). Cytotoxicity of shikonin metabolites with biotransformation of human intestinal bacteria. Journal of microbiology and biotechnology, 10(4), 514-517.