| 1 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
CHEMBL4521 |
NA |
55 |
18 |
0.9943 |
0.9995 |
| 2 |
1-phosphatidylinositol 3-phosphate 5-kinase |
CHEMBL1938222 |
NA |
43 |
12 |
0.9921 |
0.9628 |
| 3 |
11-beta-hydroxysteroid dehydrogenase 1 |
CHEMBL4235 |
NA |
2216 |
817 |
0.9907 |
0.9955 |
| 4 |
11-beta-hydroxysteroid dehydrogenase type 2 |
CHEMBL3746 |
NA |
145 |
41 |
0.9918 |
0.9926 |
| 5 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
CHEMBL1293255 |
NA |
221 |
86 |
0.9984 |
0.9848 |
| 6 |
17-beta-hydroxysteroid dehydrogenase 13 |
CHEMBL5305042 |
NA |
38 |
31 |
1 |
1 |
| 7 |
17-beta-hydroxysteroid dehydrogenase type 2 |
CHEMBL2789 |
NA |
475 |
29 |
0.9942 |
0.995 |
| 8 |
17-beta-hydroxysteroid dehydrogenase type 3 |
CHEMBL4234 |
NA |
175 |
36 |
0.9944 |
1 |
| 9 |
2-Hydroxyacid oxidase 1 |
CHEMBL4229 |
NA |
43 |
19 |
0.9958 |
0.9825 |
| 10 |
2-acylglycerol O-acyltransferase 2 |
CHEMBL2439944 |
NA |
90 |
54 |
0.9998 |
1 |
| 11 |
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 |
CHEMBL1958 |
NA |
13 |
11 |
0.9999 |
0.9999 |
| 12 |
3',5'-cyclic-AMP phosphodiesterase 4A |
CHEMBL254 |
NA |
292 |
165 |
0.9747 |
0.9887 |
| 13 |
3',5'-cyclic-AMP phosphodiesterase 4B |
CHEMBL275 |
NA |
1291 |
641 |
0.9883 |
0.99 |
| 14 |
3',5'-cyclic-AMP phosphodiesterase 4C |
CHEMBL291 |
NA |
100 |
72 |
0.9758 |
0.9896 |
| 15 |
3',5'-cyclic-AMP phosphodiesterase 4D |
CHEMBL288 |
NA |
867 |
368 |
0.9751 |
0.9866 |
| 16 |
3',5'-cyclic-AMP phosphodiesterase 7B |
CHEMBL4716 |
NA |
24 |
13 |
0.9054 |
0.9172 |
| 17 |
3-hydroxy-3-methylglutaryl-coenzyme A reductase |
CHEMBL402 |
NA |
97 |
48 |
0.9949 |
0.9996 |
| 18 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
CHEMBL1787 |
NA |
68 |
18 |
0.9997 |
0.9996 |
| 19 |
3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
CHEMBL1856 |
NA |
160 |
85 |
0.9996 |
0.9999 |
| 20 |
3-phosphoinositide-dependent protein kinase 1 |
CHEMBL2534 |
NA |
200 |
76 |
0.9739 |
0.9761 |
| 21 |
4-hydroxyphenylpyruvate dioxygenase |
CHEMBL1861 |
NA |
111 |
45 |
0.9999 |
0.997 |
| 22 |
5'-AMP-activated protein kinase catalytic subunit alpha-1 |
CHEMBL4045 |
NA |
48 |
34 |
0.907 |
0.9796 |
| 23 |
5'-AMP-activated protein kinase catalytic subunit alpha-2 |
CHEMBL2116 |
NA |
36 |
32 |
0.8478 |
0.8964 |
| 24 |
5'-nucleotidase |
CHEMBL5957 |
NA |
360 |
71 |
0.9811 |
0.9491 |
| 25 |
5-hydroxytryptamine receptor 1A |
CHEMBL214 |
NA |
3638 |
819 |
0.9815 |
0.9865 |
| 26 |
5-hydroxytryptamine receptor 1B |
CHEMBL1898 |
NA |
534 |
180 |
0.9755 |
0.9736 |
| 27 |
5-hydroxytryptamine receptor 1D |
CHEMBL1983 |
NA |
516 |
186 |
0.9804 |
0.9928 |
| 28 |
5-hydroxytryptamine receptor 1E |
CHEMBL2182 |
NA |
41 |
12 |
0.9504 |
0.9893 |
| 29 |
5-hydroxytryptamine receptor 1F |
CHEMBL1805 |
NA |
42 |
23 |
0.997 |
0.9986 |
| 30 |
5-hydroxytryptamine receptor 2A |
CHEMBL224 |
NA |
3335 |
881 |
0.9789 |
0.9856 |
| 31 |
5-hydroxytryptamine receptor 2B |
CHEMBL1833 |
NA |
1140 |
342 |
0.9681 |
0.9669 |
| 32 |
5-hydroxytryptamine receptor 2C |
CHEMBL225 |
NA |
2273 |
492 |
0.9788 |
0.9812 |
| 33 |
5-hydroxytryptamine receptor 3A |
CHEMBL1899 |
NA |
393 |
103 |
0.9769 |
0.9823 |
| 34 |
5-hydroxytryptamine receptor 4 |
CHEMBL1875 |
NA |
499 |
105 |
0.9943 |
0.9942 |
| 35 |
5-hydroxytryptamine receptor 5A |
CHEMBL3426 |
NA |
186 |
82 |
0.9523 |
0.95 |
| 36 |
5-hydroxytryptamine receptor 6 |
CHEMBL3371 |
NA |
3356 |
459 |
0.9905 |
0.9861 |
| 37 |
5-hydroxytryptamine receptor 7 |
CHEMBL3155 |
NA |
2238 |
357 |
0.9845 |
0.9856 |
| 38 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
CHEMBL3421524 |
NA |
33 |
16 |
1 |
1 |
| 39 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 |
CHEMBL3421525 |
NA |
30 |
17 |
1 |
1 |
| 40 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 |
CHEMBL2331053 |
NA |
108 |
41 |
0.9962 |
0.9964 |
| 41 |
72 kDa type IV collagenase |
CHEMBL333 |
NA |
1515 |
954 |
0.9801 |
0.9908 |
| 42 |
A disintegrin and metalloproteinase with thrombospondin motifs 4 |
CHEMBL2318 |
NA |
137 |
71 |
0.9859 |
0.9779 |
| 43 |
A disintegrin and metalloproteinase with thrombospondin motifs 5 |
CHEMBL2285 |
NA |
273 |
132 |
0.9958 |
0.9902 |
| 44 |
A disintegrin and metalloproteinase with thrombospondin motifs 7 |
CHEMBL5724789 |
NA |
48 |
47 |
1 |
1 |
| 45 |
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
CHEMBL4660 |
NA |
236 |
74 |
0.9996 |
1 |
| 46 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
C1156Y |
1035 |
21 |
0.9875 |
0.9758 |
| 47 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
F1174L |
1035 |
23 |
0.9875 |
0.9901 |
| 48 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
G1202R |
1035 |
57 |
0.9875 |
0.9859 |
| 49 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
L1196M |
1035 |
181 |
0.9875 |
0.9964 |
| 50 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
NA |
1035 |
579 |
0.9875 |
0.9886 |
| 51 |
AMP deaminase 2 |
CHEMBL2997 |
NA |
22 |
14 |
1 |
1 |
| 52 |
AP2-associated protein kinase 1 |
CHEMBL3830 |
NA |
278 |
161 |
0.9746 |
0.9607 |
| 53 |
ATP-citrate synthase |
CHEMBL3720 |
NA |
63 |
29 |
0.9935 |
0.9932 |
| 54 |
ATP-dependent Clp protease proteolytic subunit, mitochondrial |
CHEMBL4523305 |
NA |
132 |
13 |
0.9878 |
0.9481 |
| 55 |
ATP-dependent RNA helicase DDX3X |
CHEMBL5553 |
NA |
108 |
34 |
0.9904 |
0.9864 |
| 56 |
ATP-dependent translocase ABCB1 |
CHEMBL4302 |
NA |
1505 |
32 |
0.9675 |
0.9079 |
| 57 |
ATP-sensitive inward rectifier potassium channel 1 |
CHEMBL1293292 |
NA |
252 |
12 |
0.9988 |
1 |
| 58 |
ATPase family AAA domain-containing protein 2 |
CHEMBL2150837 |
NA |
193 |
19 |
0.9801 |
0.9589 |
| 59 |
Acetyl-CoA acetyltransferase, mitochondrial |
CHEMBL2616 |
NA |
13 |
10 |
0.9292 |
0.9715 |
| 60 |
Acetyl-CoA carboxylase 1 |
CHEMBL3351 |
NA |
287 |
103 |
0.9934 |
0.9915 |
| 61 |
Acetyl-CoA carboxylase 2 |
CHEMBL4829 |
NA |
380 |
175 |
0.995 |
0.9943 |
| 62 |
Acetyl-coenzyme A synthetase, cytoplasmic |
CHEMBL4523467 |
NA |
23 |
12 |
1 |
1 |
| 63 |
Acetylcholine receptor subunit epsilon |
CHEMBL2484 |
NA |
32 |
24 |
0.9701 |
0.9772 |
| 64 |
Acetylcholinesterase |
CHEMBL220 |
NA |
3626 |
1395 |
0.9697 |
0.9823 |
| 65 |
Acid ceramidase |
CHEMBL5463 |
NA |
151 |
32 |
0.9964 |
0.9945 |
| 66 |
Acrosin |
CHEMBL2738 |
NA |
57 |
22 |
0.9962 |
0.9999 |
| 67 |
Activated CDC42 kinase 1 |
CHEMBL4599 |
NA |
225 |
106 |
0.9772 |
0.9583 |
| 68 |
Activin receptor type-1 |
CHEMBL5903 |
R206H |
322 |
39 |
0.9869 |
0.9999 |
| 69 |
Activin receptor type-1 |
CHEMBL5903 |
NA |
322 |
211 |
0.9869 |
0.9864 |
| 70 |
Activin receptor type-1-like |
CHEMBL5311 |
NA |
66 |
47 |
0.9655 |
0.9614 |
| 71 |
Activin receptor type-1B |
CHEMBL5310 |
NA |
42 |
22 |
0.9536 |
0.9844 |
| 72 |
Activin receptor type-2A |
CHEMBL5616 |
NA |
32 |
11 |
0.9372 |
0.9068 |
| 73 |
Acyl-protein thioesterase 1 |
CHEMBL1681631 |
NA |
11 |
11 |
0.813 |
0.8366 |
| 74 |
Adenomatous polyposis coli protein |
CHEMBL3233 |
NA |
66 |
35 |
0.9999 |
0.9999 |
| 75 |
Adenosine kinase |
CHEMBL3589 |
NA |
195 |
88 |
0.9965 |
0.9945 |
| 76 |
Adenosine receptor A1 |
CHEMBL226 |
NA |
3887 |
233 |
0.9852 |
0.9845 |
| 77 |
Adenosine receptor A2a |
CHEMBL251 |
NA |
4465 |
455 |
0.9853 |
0.9876 |
| 78 |
Adenosine receptor A2b |
CHEMBL255 |
NA |
2147 |
164 |
0.993 |
0.9888 |
| 79 |
Adenosine receptor A3 |
CHEMBL256 |
NA |
3478 |
149 |
0.9886 |
0.967 |
| 80 |
Adenosylhomocysteinase |
CHEMBL2664 |
NA |
121 |
51 |
0.9932 |
0.9813 |
| 81 |
Adenylate cyclase type 10 |
CHEMBL5854 |
NA |
45 |
37 |
0.9671 |
0.9778 |
| 82 |
Adrenocorticotropic hormone receptor |
CHEMBL1965 |
NA |
22 |
22 |
1 |
1 |
| 83 |
Advanced glycosylation end product-specific receptor |
CHEMBL2176846 |
NA |
47 |
13 |
0.9475 |
0.9274 |
| 84 |
Albumin |
CHEMBL3253 |
NA |
60 |
32 |
0.9544 |
0.9473 |
| 85 |
Alcohol dehydrogenase class-3 |
CHEMBL4116 |
NA |
40 |
38 |
0.9898 |
0.9999 |
| 86 |
Aldehyde dehydrogenase 1A1 |
CHEMBL3577 |
NA |
288 |
203 |
0.9898 |
0.9941 |
| 87 |
Aldehyde dehydrogenase, dimeric NADP-preferring |
CHEMBL3578 |
NA |
71 |
22 |
0.9973 |
0.9999 |
| 88 |
Aldo-keto reductase family 1 member A1 |
CHEMBL2246 |
NA |
68 |
19 |
0.999 |
0.9989 |
| 89 |
Aldo-keto reductase family 1 member B1 |
CHEMBL1900 |
NA |
399 |
136 |
0.9887 |
0.9896 |
| 90 |
Aldo-keto reductase family 1 member B10 |
CHEMBL5983 |
NA |
96 |
14 |
0.9956 |
0.9931 |
| 91 |
Aldo-keto reductase family 1 member C1 |
CHEMBL5905 |
NA |
103 |
19 |
0.959 |
0.9774 |
| 92 |
Aldo-keto reductase family 1 member C2 |
CHEMBL5847 |
NA |
222 |
36 |
0.9853 |
0.9685 |
| 93 |
Aldo-keto reductase family 1 member C3 |
CHEMBL4681 |
NA |
556 |
154 |
0.9745 |
0.9851 |
| 94 |
Aldo-keto reductase family 1 member C4 |
CHEMBL4999 |
NA |
52 |
11 |
0.9841 |
0.9979 |
| 95 |
Alkaline phosphatase, tissue-nonspecific isozyme |
CHEMBL5979 |
NA |
133 |
34 |
0.9954 |
0.9928 |
| 96 |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
CHEMBL2321630 |
NA |
124 |
29 |
0.9946 |
0.9538 |
| 97 |
Alpha-1A adrenergic receptor |
CHEMBL229 |
NA |
947 |
292 |
0.9784 |
0.9815 |
| 98 |
Alpha-1B adrenergic receptor |
CHEMBL232 |
NA |
617 |
155 |
0.981 |
0.987 |
| 99 |
Alpha-1D adrenergic receptor |
CHEMBL223 |
NA |
576 |
130 |
0.9873 |
0.9921 |
| 100 |
Alpha-2A adrenergic receptor |
CHEMBL1867 |
NA |
549 |
143 |
0.9729 |
0.9646 |
| 101 |
Alpha-2B adrenergic receptor |
CHEMBL1942 |
NA |
277 |
64 |
0.9611 |
0.9684 |
| 102 |
Alpha-2C adrenergic receptor |
CHEMBL1916 |
NA |
335 |
98 |
0.9714 |
0.9842 |
| 103 |
Alpha-amylase 1A |
CHEMBL2478 |
NA |
36 |
10 |
0.9858 |
0.999 |
| 104 |
Alpha-ketoglutarate-dependent dioxygenase FTO |
CHEMBL2331065 |
NA |
167 |
28 |
0.9702 |
0.9143 |
| 105 |
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 |
CHEMBL3112376 |
NA |
53 |
18 |
0.9987 |
1 |
| 106 |
Alpha-synuclein |
CHEMBL6152 |
NA |
208 |
74 |
0.9617 |
0.9686 |
| 107 |
Amine oxidase [copper-containing] 3 |
CHEMBL3437 |
NA |
185 |
22 |
0.9993 |
0.9999 |
| 108 |
Amine oxidase [flavin-containing] A |
CHEMBL1951 |
NA |
2033 |
607 |
0.9758 |
0.9813 |
| 109 |
Amine oxidase [flavin-containing] B |
CHEMBL2039 |
NA |
3526 |
1015 |
0.9741 |
0.9871 |
| 110 |
Aminopeptidase N |
CHEMBL1907 |
NA |
265 |
67 |
0.9884 |
0.9977 |
| 111 |
Amyloid-beta precursor protein |
CHEMBL2487 |
NA |
1242 |
371 |
0.9724 |
0.9769 |
| 112 |
Androgen receptor |
CHEMBL1871 |
NA |
1776 |
365 |
0.9893 |
0.9965 |
| 113 |
Angiopoietin-1 receptor |
CHEMBL4128 |
NA |
466 |
330 |
0.972 |
0.9782 |
| 114 |
Angiotensin-converting enzyme |
CHEMBL1808 |
NA |
126 |
86 |
0.987 |
0.9987 |
| 115 |
Angiotensin-converting enzyme 2 |
CHEMBL3736 |
NA |
64 |
42 |
0.9459 |
0.9698 |
| 116 |
Apoptosis regulator Bcl-2 |
CHEMBL4860 |
G101V |
816 |
29 |
0.9862 |
0.9931 |
| 117 |
Apoptosis regulator Bcl-2 |
CHEMBL4860 |
NA |
816 |
438 |
0.9862 |
0.9922 |
| 118 |
Arachidonate 5-lipoxygenase-activating protein |
CHEMBL4550 |
NA |
369 |
161 |
0.9955 |
0.9977 |
| 119 |
Arginase-1 |
CHEMBL1075097 |
NA |
217 |
79 |
0.997 |
1 |
| 120 |
Arginase-2, mitochondrial |
CHEMBL1795148 |
NA |
67 |
30 |
1 |
0.9998 |
| 121 |
Aromatase |
CHEMBL1978 |
NA |
2198 |
640 |
0.99 |
0.9962 |
| 122 |
Aryl hydrocarbon receptor |
CHEMBL3201 |
NA |
132 |
25 |
0.9757 |
0.9277 |
| 123 |
Arylamine N-acetyltransferase 1 |
CHEMBL5101 |
NA |
38 |
17 |
0.9999 |
1 |
| 124 |
Atypical chemokine receptor 3 |
CHEMBL2010631 |
NA |
313 |
14 |
0.9869 |
0.9602 |
| 125 |
Aurora kinase A |
CHEMBL4722 |
NA |
1103 |
528 |
0.9689 |
0.9681 |
| 126 |
Aurora kinase B |
CHEMBL2185 |
NA |
984 |
496 |
0.9735 |
0.9747 |
| 127 |
Aurora kinase C |
CHEMBL3935 |
NA |
65 |
46 |
0.9126 |
0.9133 |
| 128 |
Autotaxin |
CHEMBL3691 |
NA |
724 |
337 |
0.9827 |
0.9934 |
| 129 |
B-cell lymphoma 6 protein |
CHEMBL4105786 |
NA |
235 |
44 |
0.9918 |
0.9712 |
| 130 |
B1 bradykinin receptor |
CHEMBL4308 |
NA |
483 |
192 |
0.9988 |
0.9987 |
| 131 |
B2 bradykinin receptor |
CHEMBL3157 |
NA |
144 |
16 |
0.9951 |
0.9805 |
| 132 |
BDNF/NT-3 growth factors receptor |
CHEMBL4898 |
NA |
433 |
174 |
0.9696 |
0.9564 |
| 133 |
BMP-2-inducible protein kinase |
CHEMBL4522 |
NA |
58 |
26 |
0.9342 |
0.8732 |
| 134 |
Baculoviral IAP repeat-containing protein 2 |
CHEMBL5462 |
NA |
237 |
124 |
0.9995 |
0.9995 |
| 135 |
Baculoviral IAP repeat-containing protein 3 |
CHEMBL5335 |
NA |
90 |
58 |
0.9993 |
0.9999 |
| 136 |
Bcl-2-like protein 1 |
CHEMBL4625 |
NA |
526 |
265 |
0.9907 |
0.9856 |
| 137 |
Bcl-2-like protein 2 |
CHEMBL4677 |
NA |
58 |
20 |
0.9683 |
0.9279 |
| 138 |
Bcl-2-related protein A1 |
CHEMBL6044 |
NA |
93 |
18 |
0.9677 |
0.8742 |
| 139 |
Bcl2-associated agonist of cell death |
CHEMBL3817 |
NA |
49 |
17 |
0.9687 |
0.9415 |
| 140 |
Bcr/Abl fusion protein |
CHEMBL2096618 |
NA |
431 |
15 |
0.9887 |
0.9464 |
| 141 |
Beta-1 adrenergic receptor |
CHEMBL213 |
NA |
857 |
80 |
0.9897 |
0.9685 |
| 142 |
Beta-2 adrenergic receptor |
CHEMBL210 |
NA |
1087 |
171 |
0.9887 |
0.9855 |
| 143 |
Beta-3 adrenergic receptor |
CHEMBL246 |
NA |
826 |
31 |
0.9932 |
0.9848 |
| 144 |
Beta-adrenergic receptor kinase 1 |
CHEMBL4079 |
NA |
224 |
41 |
0.9783 |
0.9679 |
| 145 |
Beta-galactoside alpha-2,6-sialyltransferase 1 |
CHEMBL3596075 |
NA |
39 |
20 |
0.9998 |
0.9985 |
| 146 |
Beta-glucosidase |
CHEMBL3761 |
NA |
64 |
49 |
1 |
1 |
| 147 |
Beta-glucuronidase |
CHEMBL2728 |
NA |
264 |
119 |
0.977 |
0.9817 |
| 148 |
Beta-secretase 1 |
CHEMBL4822 |
NA |
2980 |
1288 |
0.9818 |
0.988 |
| 149 |
Beta-secretase 2 |
CHEMBL2525 |
NA |
276 |
179 |
0.9949 |
0.9955 |
| 150 |
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 |
CHEMBL4523345 |
NA |
24 |
13 |
0.9488 |
0.9143 |
| 151 |
Bifunctional epoxide hydrolase 2 |
CHEMBL2409 |
NA |
2058 |
1413 |
0.987 |
0.9939 |
| 152 |
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial |
CHEMBL3621036 |
NA |
46 |
21 |
1 |
0.9634 |
| 153 |
Bifunctional purine biosynthesis protein ATIC |
CHEMBL2518 |
NA |
64 |
11 |
0.9918 |
0.9965 |
| 154 |
Bile acid receptor |
CHEMBL2047 |
NA |
1378 |
419 |
0.987 |
0.9929 |
| 155 |
Bis(5'-adenosyl)-triphosphatase |
CHEMBL1795151 |
NA |
21 |
13 |
0.9057 |
0.8964 |
| 156 |
Bombesin receptor subtype-3 |
CHEMBL4080 |
NA |
165 |
36 |
0.9985 |
0.9999 |
| 157 |
Bone morphogenetic protein receptor type-1A |
CHEMBL5275 |
NA |
65 |
30 |
0.9663 |
0.944 |
| 158 |
Bone morphogenetic protein receptor type-1B |
CHEMBL5476 |
NA |
40 |
25 |
0.9692 |
0.986 |
| 159 |
Bone morphogenetic protein receptor type-2 |
CHEMBL5467 |
NA |
43 |
15 |
0.9667 |
0.907 |
| 160 |
Branched-chain-amino-acid aminotransferase, cytosolic |
CHEMBL4679 |
NA |
70 |
13 |
0.9842 |
0.974 |
| 161 |
Branched-chain-amino-acid aminotransferase, mitochondrial |
CHEMBL3616354 |
NA |
120 |
45 |
0.9937 |
0.9983 |
| 162 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 |
CHEMBL5393 |
NA |
1017 |
25 |
0.9542 |
0.9087 |
| 163 |
Bromodomain adjacent to zinc finger domain protein 2A |
CHEMBL3108642 |
NA |
97 |
13 |
0.9847 |
0.9155 |
| 164 |
Bromodomain testis-specific protein |
CHEMBL1795185 |
NA |
148 |
43 |
0.9516 |
0.9687 |
| 165 |
Bromodomain-containing protein 2 |
CHEMBL1293289 |
NA |
276 |
110 |
0.9713 |
0.9799 |
| 166 |
Bromodomain-containing protein 3 |
CHEMBL1795186 |
NA |
262 |
118 |
0.9771 |
0.9844 |
| 167 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
N140A |
3824 |
17 |
0.9819 |
0.9978 |
| 168 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
N433A |
3824 |
18 |
0.9819 |
1 |
| 169 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
Y97A |
3824 |
125 |
0.9819 |
0.9872 |
| 170 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
Y390A |
3824 |
127 |
0.9819 |
0.9866 |
| 171 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
NA |
3824 |
1260 |
0.9819 |
0.9907 |
| 172 |
Bromodomain-containing protein 7 |
CHEMBL3085622 |
NA |
46 |
14 |
0.9565 |
0.9348 |
| 173 |
Bromodomain-containing protein 9 |
CHEMBL3108640 |
NA |
225 |
89 |
0.991 |
0.9977 |
| 174 |
C-C chemokine receptor type 1 |
CHEMBL2413 |
NA |
409 |
45 |
0.9938 |
0.974 |
| 175 |
C-C chemokine receptor type 2 |
CHEMBL4015 |
NA |
1391 |
478 |
0.9953 |
0.9957 |
| 176 |
C-C chemokine receptor type 3 |
CHEMBL3473 |
NA |
657 |
86 |
0.9936 |
0.9935 |
| 177 |
C-C chemokine receptor type 4 |
CHEMBL2414 |
NA |
347 |
20 |
0.9915 |
0.9995 |
| 178 |
C-C chemokine receptor type 5 |
CHEMBL274 |
NA |
1089 |
103 |
0.9891 |
0.9976 |
| 179 |
C-C chemokine receptor type 9 |
CHEMBL5815 |
NA |
120 |
45 |
0.9938 |
1 |
| 180 |
C-X-C chemokine receptor type 1 |
CHEMBL4029 |
NA |
152 |
16 |
0.976 |
0.9397 |
| 181 |
C-X-C chemokine receptor type 2 |
CHEMBL2434 |
NA |
711 |
127 |
0.9973 |
0.9799 |
| 182 |
C-X-C chemokine receptor type 3 |
CHEMBL4441 |
NA |
832 |
77 |
0.9957 |
0.9634 |
| 183 |
C-X-C chemokine receptor type 4 |
CHEMBL2107 |
NA |
531 |
33 |
0.9865 |
0.9709 |
| 184 |
C3a anaphylatoxin chemotactic receptor |
CHEMBL4761 |
NA |
152 |
27 |
0.9999 |
0.9999 |
| 185 |
CDGSH iron-sulfur domain-containing protein 1 |
CHEMBL1795168 |
NA |
73 |
13 |
0.9293 |
0.9266 |
| 186 |
COP9 signalosome complex subunit 5 |
CHEMBL4105809 |
NA |
38 |
11 |
0.9704 |
0.9172 |
| 187 |
CREB-binding protein |
CHEMBL5747 |
NA |
491 |
218 |
0.9751 |
0.9767 |
| 188 |
CTP synthase 1 |
CHEMBL5291523 |
NA |
27 |
12 |
0.962 |
1 |
| 189 |
Calcitonin gene-related peptide type 1 receptor |
CHEMBL3798 |
NA |
542 |
134 |
0.9982 |
0.9999 |
| 190 |
Calcium/calmodulin-dependent protein kinase kinase 1 |
CHEMBL5256 |
NA |
34 |
24 |
0.9163 |
0.9397 |
| 191 |
Calcium/calmodulin-dependent protein kinase kinase 2 |
CHEMBL5284 |
NA |
107 |
77 |
0.9584 |
0.9636 |
| 192 |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
CHEMBL2801 |
NA |
57 |
16 |
0.9638 |
0.9307 |
| 193 |
Calpain-1 catalytic subunit |
CHEMBL3891 |
NA |
246 |
92 |
0.993 |
0.9941 |
| 194 |
Cannabinoid receptor 1 |
CHEMBL218 |
NA |
3682 |
506 |
0.986 |
0.9904 |
| 195 |
Cannabinoid receptor 2 |
CHEMBL253 |
NA |
4237 |
737 |
0.9897 |
0.9938 |
| 196 |
Carbonic anhydrase 1 |
CHEMBL261 |
NA |
5499 |
3297 |
0.9908 |
0.9895 |
| 197 |
Carbonic anhydrase 12 |
CHEMBL3242 |
NA |
4419 |
3681 |
0.9905 |
0.9905 |
| 198 |
Carbonic anhydrase 13 |
CHEMBL3912 |
NA |
364 |
198 |
0.9914 |
0.9973 |
| 199 |
Carbonic anhydrase 14 |
CHEMBL3510 |
NA |
654 |
415 |
0.9902 |
0.9893 |
| 200 |
Carbonic anhydrase 2 |
CHEMBL205 |
NA |
6038 |
4760 |
0.9903 |
0.9933 |
| 201 |
Carbonic anhydrase 3 |
CHEMBL2885 |
NA |
180 |
53 |
0.9769 |
0.9364 |
| 202 |
Carbonic anhydrase 4 |
CHEMBL3729 |
NA |
1319 |
684 |
0.9918 |
0.9909 |
| 203 |
Carbonic anhydrase 5A, mitochondrial |
CHEMBL4789 |
NA |
570 |
308 |
0.9855 |
0.9854 |
| 204 |
Carbonic anhydrase 5B, mitochondrial |
CHEMBL3969 |
NA |
490 |
247 |
0.9908 |
0.993 |
| 205 |
Carbonic anhydrase 6 |
CHEMBL3025 |
NA |
371 |
117 |
0.9861 |
0.9782 |
| 206 |
Carbonic anhydrase 7 |
CHEMBL2326 |
NA |
1414 |
1128 |
0.9931 |
0.9928 |
| 207 |
Carbonic anhydrase 9 |
CHEMBL3594 |
NA |
5410 |
4219 |
0.9903 |
0.9916 |
| 208 |
Carboxypeptidase A1 |
CHEMBL2088 |
NA |
47 |
25 |
0.9998 |
0.9999 |
| 209 |
Carboxypeptidase A2 |
CHEMBL4939 |
NA |
10 |
10 |
1 |
1 |
| 210 |
Carboxypeptidase A4 |
CHEMBL2644 |
NA |
10 |
10 |
1 |
1 |
| 211 |
Carboxypeptidase B |
CHEMBL2552 |
NA |
63 |
21 |
0.9822 |
0.9987 |
| 212 |
Carboxypeptidase B2 |
CHEMBL3419 |
NA |
185 |
109 |
0.9999 |
0.9999 |
| 213 |
Carnitine O-palmitoyltransferase 1, liver isoform |
CHEMBL1293194 |
NA |
16 |
11 |
0.9567 |
0.9701 |
| 214 |
Casein kinase I isoform alpha |
CHEMBL2793 |
NA |
45 |
12 |
0.9494 |
0.8824 |
| 215 |
Casein kinase I isoform delta |
CHEMBL2828 |
NA |
296 |
105 |
0.9779 |
0.9731 |
| 216 |
Casein kinase I isoform epsilon |
CHEMBL4937 |
NA |
203 |
73 |
0.9483 |
0.925 |
| 217 |
Casein kinase I isoform gamma-2 |
CHEMBL2543 |
NA |
30 |
11 |
0.9029 |
0.8366 |
| 218 |
Casein kinase II subunit alpha |
CHEMBL3629 |
NA |
328 |
94 |
0.9723 |
0.9583 |
| 219 |
Casein kinase II subunit alpha' |
CHEMBL4070 |
NA |
158 |
29 |
0.9724 |
0.8381 |
| 220 |
Caspase-1 |
CHEMBL4801 |
NA |
364 |
181 |
0.9928 |
0.9974 |
| 221 |
Caspase-3 |
CHEMBL2334 |
NA |
713 |
373 |
0.9936 |
0.9945 |
| 222 |
Caspase-6 |
CHEMBL3308 |
NA |
79 |
34 |
0.9918 |
0.9849 |
| 223 |
Caspase-7 |
CHEMBL3468 |
NA |
317 |
213 |
0.9982 |
0.9992 |
| 224 |
Caspase-8 |
CHEMBL3776 |
NA |
135 |
50 |
0.9895 |
0.9991 |
| 225 |
Catechol O-methyltransferase |
CHEMBL2023 |
NA |
131 |
16 |
0.9954 |
0.9415 |
| 226 |
Catenin beta-1 |
CHEMBL5866 |
NA |
98 |
13 |
0.9549 |
0.8357 |
| 227 |
Cathepsin B |
CHEMBL4072 |
NA |
915 |
431 |
0.9817 |
0.9905 |
| 228 |
Cathepsin D |
CHEMBL2581 |
NA |
763 |
240 |
0.9901 |
0.9963 |
| 229 |
Cathepsin E |
CHEMBL3092 |
NA |
30 |
17 |
0.8809 |
0.9573 |
| 230 |
Cathepsin K |
CHEMBL268 |
NA |
1239 |
892 |
0.9922 |
0.9971 |
| 231 |
Cathepsin L2 |
CHEMBL3272 |
NA |
91 |
29 |
0.9897 |
0.9955 |
| 232 |
Cathepsin S |
CHEMBL2954 |
NA |
1358 |
876 |
0.9969 |
0.9979 |
| 233 |
Cell division cycle 7-related protein kinase |
CHEMBL5443 |
NA |
189 |
121 |
0.9932 |
0.9923 |
| 234 |
Centromere-associated protein E |
CHEMBL5870 |
NA |
27 |
18 |
0.9295 |
0.9989 |
| 235 |
Ceramide glucosyltransferase |
CHEMBL2063 |
NA |
152 |
73 |
0.9981 |
0.9937 |
| 236 |
Chitotriosidase-1 |
CHEMBL3080 |
NA |
118 |
14 |
0.9953 |
0.9662 |
| 237 |
Cholecystokinin receptor type A |
CHEMBL1901 |
NA |
237 |
104 |
0.9901 |
0.9878 |
| 238 |
Cholesteryl ester transfer protein |
CHEMBL3572 |
NA |
614 |
346 |
0.9985 |
1 |
| 239 |
Choline kinase alpha |
CHEMBL3117 |
NA |
81 |
57 |
0.9907 |
0.9893 |
| 240 |
Choline/ethanolaminephosphotransferase 1 |
CHEMBL4105740 |
NA |
44 |
27 |
0.9908 |
0.9847 |
| 241 |
Cholinesterase |
CHEMBL1914 |
NA |
2654 |
1055 |
0.9771 |
0.9896 |
| 242 |
Chromatin remodeling regulator CECR2 |
CHEMBL3108639 |
NA |
128 |
50 |
0.9885 |
0.9783 |
| 243 |
Chymase |
CHEMBL4068 |
NA |
156 |
105 |
0.9875 |
0.9971 |
| 244 |
Chymotrypsinogen B |
CHEMBL4796 |
NA |
26 |
14 |
0.8962 |
0.9406 |
| 245 |
Citron Rho-interacting kinase |
CHEMBL5579 |
NA |
87 |
66 |
0.948 |
0.9388 |
| 246 |
Coagulation factor IX |
CHEMBL2016 |
NA |
304 |
229 |
0.9942 |
0.9998 |
| 247 |
Coagulation factor VII |
CHEMBL3991 |
NA |
262 |
186 |
0.9921 |
0.9985 |
| 248 |
Coagulation factor X |
CHEMBL244 |
NA |
2612 |
1820 |
0.9942 |
0.9964 |
| 249 |
Coagulation factor XI |
CHEMBL2820 |
NA |
704 |
539 |
0.9952 |
0.9965 |
| 250 |
Coagulation factor XII |
CHEMBL2821 |
NA |
132 |
51 |
0.9843 |
0.9978 |
| 251 |
Coagulation factor XIII A chain |
CHEMBL4530 |
NA |
91 |
67 |
0.9932 |
0.9991 |
| 252 |
Cocaine esterase |
CHEMBL3180 |
NA |
229 |
83 |
0.9769 |
0.9769 |
| 253 |
Collagenase 3 |
CHEMBL280 |
NA |
1309 |
933 |
0.986 |
0.9942 |
| 254 |
Complement C1s subcomponent |
CHEMBL3913 |
NA |
59 |
33 |
0.9997 |
0.9999 |
| 255 |
Complement factor B |
CHEMBL5731 |
NA |
40 |
15 |
0.9838 |
1 |
| 256 |
Complement factor D |
CHEMBL2176771 |
NA |
112 |
55 |
0.9889 |
0.9909 |
| 257 |
Corticotropin-releasing factor receptor 1 |
CHEMBL1800 |
NA |
880 |
116 |
0.9999 |
1 |
| 258 |
Cyclic GMP-AMP synthase |
CHEMBL4105728 |
NA |
113 |
20 |
0.9759 |
0.9218 |
| 259 |
Cyclin-G-associated kinase |
CHEMBL4355 |
NA |
236 |
81 |
0.9641 |
0.9421 |
| 260 |
Cyclin-dependent kinase 1 |
CHEMBL308 |
NA |
337 |
189 |
0.9653 |
0.9561 |
| 261 |
Cyclin-dependent kinase 12 |
CHEMBL3559692 |
NA |
38 |
33 |
0.919 |
0.9224 |
| 262 |
Cyclin-dependent kinase 19 |
CHEMBL6002 |
NA |
21 |
12 |
0.8864 |
0.7956 |
| 263 |
Cyclin-dependent kinase 2 |
CHEMBL301 |
NA |
720 |
378 |
0.9509 |
0.9555 |
| 264 |
Cyclin-dependent kinase 3 |
CHEMBL4442 |
NA |
16 |
13 |
0.7444 |
0.6935 |
| 265 |
Cyclin-dependent kinase 4 |
CHEMBL331 |
NA |
217 |
155 |
0.9657 |
0.9684 |
| 266 |
Cyclin-dependent kinase 5 |
CHEMBL4036 |
NA |
116 |
74 |
0.9432 |
0.9119 |
| 267 |
Cyclin-dependent kinase 6 |
CHEMBL2508 |
NA |
148 |
104 |
0.9741 |
0.9609 |
| 268 |
Cyclin-dependent kinase 7 |
CHEMBL3055 |
NA |
182 |
118 |
0.9662 |
0.9529 |
| 269 |
Cyclin-dependent kinase 8 |
CHEMBL5719 |
NA |
385 |
173 |
0.9828 |
0.9817 |
| 270 |
Cyclin-dependent kinase 9 |
CHEMBL3116 |
NA |
374 |
243 |
0.9679 |
0.9632 |
| 271 |
Cystathionine gamma-lyase |
CHEMBL4295745 |
NA |
43 |
16 |
0.9881 |
0.9851 |
| 272 |
Cysteine protease ATG4B |
CHEMBL1741221 |
NA |
54 |
26 |
0.9441 |
0.9781 |
| 273 |
Cytochrome P450 11B2, mitochondrial |
CHEMBL2722 |
NA |
774 |
13 |
0.9974 |
0.9914 |
| 274 |
Cytochrome P450 1B1 |
CHEMBL4878 |
NA |
360 |
205 |
0.9888 |
0.9986 |
| 275 |
Cytochrome P450 26A1 |
CHEMBL5141 |
NA |
132 |
18 |
0.9999 |
0.9999 |
| 276 |
Cytochrome P450 2A6 |
CHEMBL5282 |
NA |
40 |
21 |
0.9998 |
1 |
| 277 |
Cytochrome P450 4A11 |
CHEMBL3978 |
NA |
22 |
16 |
1 |
1 |
| 278 |
Cytochrome P450 4F2 |
CHEMBL3379 |
NA |
22 |
20 |
1 |
1 |
| 279 |
Cytochrome c oxidase subunit 2 |
CHEMBL6174 |
NA |
70 |
32 |
0.9654 |
0.9651 |
| 280 |
Cytoplasmic tyrosine-protein kinase BMX |
CHEMBL3834 |
NA |
205 |
72 |
0.9693 |
0.9595 |
| 281 |
Cytosolic phospholipase A2 |
CHEMBL3816 |
NA |
201 |
114 |
0.9956 |
0.9998 |
| 282 |
D(1A) dopamine receptor |
CHEMBL2056 |
NA |
848 |
187 |
0.9818 |
0.9849 |
| 283 |
D(1B) dopamine receptor |
CHEMBL1850 |
NA |
272 |
72 |
0.9878 |
0.9863 |
| 284 |
D(2) dopamine receptor |
CHEMBL217 |
NA |
4737 |
823 |
0.985 |
0.9915 |
| 285 |
D(3) dopamine receptor |
CHEMBL234 |
NA |
3262 |
533 |
0.9861 |
0.988 |
| 286 |
D(4) dopamine receptor |
CHEMBL219 |
NA |
1707 |
301 |
0.9847 |
0.9877 |
| 287 |
D-3-phosphoglycerate dehydrogenase |
CHEMBL2311243 |
NA |
205 |
73 |
0.9905 |
0.9858 |
| 288 |
D-amino-acid oxidase |
CHEMBL5485 |
NA |
243 |
115 |
0.9993 |
0.999 |
| 289 |
DCN1-like protein 1 |
CHEMBL4105838 |
NA |
229 |
87 |
0.9981 |
0.9954 |
| 290 |
DNA (cytosine-5)-methyltransferase 1 |
CHEMBL1993 |
NA |
193 |
78 |
0.9749 |
0.9872 |
| 291 |
DNA (cytosine-5)-methyltransferase 3A |
CHEMBL1992 |
NA |
52 |
22 |
0.955 |
0.9939 |
| 292 |
DNA polymerase beta |
CHEMBL2392 |
NA |
36 |
14 |
0.9872 |
0.9932 |
| 293 |
DNA polymerase theta |
CHEMBL6025 |
NA |
116 |
62 |
0.9925 |
0.9998 |
| 294 |
DNA repair nuclease/redox regulator APEX1 |
CHEMBL5619 |
NA |
90 |
38 |
0.9478 |
0.9413 |
| 295 |
DNA repair protein RAD51 homolog 1 |
CHEMBL2034807 |
NA |
99 |
20 |
0.9883 |
0.938 |
| 296 |
DNA topoisomerase 1 |
CHEMBL1781 |
NA |
181 |
75 |
0.9751 |
0.984 |
| 297 |
DNA topoisomerase 2-alpha |
CHEMBL1806 |
NA |
340 |
143 |
0.969 |
0.9522 |
| 298 |
DNA topoisomerase 2-beta |
CHEMBL3396 |
NA |
24 |
12 |
0.8701 |
0.8406 |
| 299 |
DNA-dependent protein kinase catalytic subunit |
CHEMBL3142 |
NA |
602 |
327 |
0.9846 |
0.9837 |
| 300 |
Death-associated protein kinase 1 |
CHEMBL2558 |
NA |
50 |
17 |
0.9161 |
0.8165 |
| 301 |
Death-associated protein kinase 2 |
CHEMBL3123 |
NA |
22 |
12 |
0.9069 |
0.9152 |
| 302 |
Death-associated protein kinase 3 |
CHEMBL2468 |
NA |
56 |
34 |
0.9124 |
0.9057 |
| 303 |
Delta-type opioid receptor |
CHEMBL236 |
NA |
2213 |
326 |
0.9877 |
0.9961 |
| 304 |
Deoxycytidine kinase |
CHEMBL2447 |
NA |
99 |
46 |
0.9956 |
0.9802 |
| 305 |
Deoxyhypusine synthase |
CHEMBL4415 |
NA |
59 |
17 |
0.9933 |
0.9947 |
| 306 |
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
CHEMBL5203 |
NA |
84 |
24 |
0.9884 |
0.9588 |
| 307 |
Diacylglycerol O-acyltransferase 1 |
CHEMBL6009 |
NA |
580 |
183 |
0.9967 |
0.9993 |
| 308 |
Dihydrofolate reductase |
CHEMBL202 |
NA |
548 |
247 |
0.9934 |
0.9981 |
| 309 |
Dihydroorotate dehydrogenase (quinone), mitochondrial |
CHEMBL1966 |
NA |
817 |
365 |
0.991 |
0.997 |
| 310 |
Dipeptidyl peptidase 1 |
CHEMBL2252 |
NA |
218 |
156 |
0.9955 |
0.9942 |
| 311 |
Dipeptidyl peptidase 2 |
CHEMBL3976 |
NA |
314 |
114 |
0.9959 |
0.9911 |
| 312 |
Dipeptidyl peptidase 4 |
CHEMBL284 |
NA |
2780 |
1768 |
0.9892 |
0.9949 |
| 313 |
Dipeptidyl peptidase 8 |
CHEMBL4657 |
NA |
580 |
220 |
0.9976 |
0.9962 |
| 314 |
Dipeptidyl peptidase 9 |
CHEMBL4793 |
NA |
407 |
124 |
0.996 |
0.9986 |
| 315 |
Discoidin domain-containing receptor 2 |
CHEMBL5122 |
NA |
219 |
119 |
0.9738 |
0.9623 |
| 316 |
Disintegrin and metalloproteinase domain-containing protein 10 |
CHEMBL5028 |
NA |
71 |
36 |
0.9932 |
0.9841 |
| 317 |
Disintegrin and metalloproteinase domain-containing protein 17 |
CHEMBL3706 |
NA |
828 |
446 |
0.9976 |
0.9995 |
| 318 |
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
CHEMBL2717 |
NA |
95 |
19 |
0.9723 |
0.9344 |
| 319 |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
CHEMBL3421 |
NA |
59 |
17 |
0.9683 |
0.9418 |
| 320 |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B |
CHEMBL4425 |
NA |
58 |
40 |
0.9193 |
0.9665 |
| 321 |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
CHEMBL4619 |
NA |
71 |
45 |
0.9831 |
0.992 |
| 322 |
Dual specificity mitogen-activated protein kinase kinase 1 |
CHEMBL3587 |
NA |
417 |
273 |
0.9726 |
0.9839 |
| 323 |
Dual specificity mitogen-activated protein kinase kinase 2 |
CHEMBL2964 |
NA |
36 |
14 |
0.8235 |
0.776 |
| 324 |
Dual specificity mitogen-activated protein kinase kinase 4 |
CHEMBL2897 |
NA |
56 |
16 |
0.948 |
0.8568 |
| 325 |
Dual specificity mitogen-activated protein kinase kinase 5 |
CHEMBL4948 |
NA |
23 |
10 |
0.8339 |
0.7506 |
| 326 |
Dual specificity mitogen-activated protein kinase kinase 7 |
CHEMBL3530 |
NA |
67 |
25 |
0.9796 |
0.9938 |
| 327 |
Dual specificity protein kinase CLK1 |
CHEMBL4224 |
NA |
653 |
284 |
0.9708 |
0.9594 |
| 328 |
Dual specificity protein kinase CLK2 |
CHEMBL4225 |
NA |
419 |
302 |
0.9528 |
0.9674 |
| 329 |
Dual specificity protein kinase CLK3 |
CHEMBL4226 |
NA |
225 |
23 |
0.9649 |
0.8653 |
| 330 |
Dual specificity protein kinase CLK4 |
CHEMBL4203 |
NA |
420 |
280 |
0.964 |
0.9778 |
| 331 |
Dual specificity protein kinase TTK |
CHEMBL3983 |
NA |
512 |
260 |
0.9909 |
0.986 |
| 332 |
Dual specificity protein phosphatase 22 |
CHEMBL3924 |
NA |
31 |
15 |
0.9865 |
0.9935 |
| 333 |
Dual specificity protein phosphatase 3 |
CHEMBL2635 |
NA |
99 |
30 |
0.9683 |
0.9716 |
| 334 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A |
CHEMBL2292 |
NA |
1361 |
600 |
0.9808 |
0.9803 |
| 335 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
CHEMBL5543 |
NA |
602 |
353 |
0.9768 |
0.9835 |
| 336 |
Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
CHEMBL4376 |
NA |
473 |
202 |
0.9805 |
0.9809 |
| 337 |
Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
CHEMBL4575 |
NA |
287 |
98 |
0.969 |
0.9812 |
| 338 |
Dual specificity tyrosine-phosphorylation-regulated kinase 4 |
CHEMBL1075115 |
NA |
169 |
66 |
0.9674 |
0.9833 |
| 339 |
Dynamin-1 |
CHEMBL4958 |
NA |
42 |
13 |
0.9748 |
0.9961 |
| 340 |
E-selectin |
CHEMBL3890 |
NA |
30 |
14 |
0.9999 |
1 |
| 341 |
E3 ubiquitin-protein ligase CBL |
CHEMBL6066351 |
NA |
22 |
15 |
1 |
1 |
| 342 |
E3 ubiquitin-protein ligase CBL-B |
CHEMBL4879459 |
NA |
127 |
47 |
0.9986 |
0.9985 |
| 343 |
E3 ubiquitin-protein ligase Mdm2 |
CHEMBL5023 |
NA |
968 |
390 |
0.988 |
0.9907 |
| 344 |
E3 ubiquitin-protein ligase XIAP |
CHEMBL4198 |
NA |
465 |
165 |
0.9983 |
0.9998 |
| 345 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
CHEMBL5925 |
NA |
275 |
73 |
0.9891 |
0.9834 |
| 346 |
Egl nine homolog 1 |
CHEMBL5697 |
NA |
454 |
208 |
0.9971 |
0.9999 |
| 347 |
Endoplasmic reticulum aminopeptidase 1 |
CHEMBL5939 |
NA |
145 |
15 |
0.9844 |
0.9999 |
| 348 |
Endoplasmic reticulum aminopeptidase 2 |
CHEMBL5043 |
NA |
154 |
16 |
0.9924 |
0.9998 |
| 349 |
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase |
CHEMBL2308 |
NA |
22 |
11 |
1 |
1 |
| 350 |
Endoplasmin |
CHEMBL1075323 |
NA |
231 |
105 |
0.9913 |
0.9886 |
| 351 |
Endothelial PAS domain-containing protein 1 |
CHEMBL1744522 |
NA |
154 |
64 |
0.9892 |
0.9987 |
| 352 |
Endothelial lipase |
CHEMBL5080 |
NA |
128 |
41 |
0.9922 |
0.9984 |
| 353 |
Endothelin receptor type B |
CHEMBL1785 |
NA |
151 |
10 |
0.9974 |
0.9213 |
| 354 |
Endothelin-1 receptor |
CHEMBL252 |
NA |
270 |
24 |
0.9959 |
0.9625 |
| 355 |
Endothelin-converting enzyme 1 |
CHEMBL4791 |
NA |
68 |
55 |
0.9917 |
0.9952 |
| 356 |
Enteropeptidase |
CHEMBL1741195 |
NA |
22 |
21 |
1 |
1 |
| 357 |
Ephrin type-A receptor 1 |
CHEMBL5810 |
NA |
31 |
13 |
0.8997 |
0.7977 |
| 358 |
Ephrin type-A receptor 2 |
CHEMBL2068 |
NA |
97 |
39 |
0.9476 |
0.9488 |
| 359 |
Ephrin type-A receptor 3 |
CHEMBL4954 |
NA |
37 |
11 |
0.8868 |
0.9001 |
| 360 |
Ephrin type-A receptor 4 |
CHEMBL3988 |
NA |
62 |
10 |
0.9251 |
0.8106 |
| 361 |
Ephrin type-A receptor 5 |
CHEMBL3987 |
NA |
19 |
11 |
0.7774 |
0.8233 |
| 362 |
Ephrin type-A receptor 6 |
CHEMBL4526 |
NA |
24 |
13 |
0.8754 |
0.8541 |
| 363 |
Ephrin type-A receptor 7 |
CHEMBL4602 |
NA |
25 |
10 |
0.805 |
0.7878 |
| 364 |
Ephrin type-A receptor 8 |
CHEMBL4134 |
NA |
30 |
11 |
0.8952 |
0.8661 |
| 365 |
Ephrin type-B receptor 2 |
CHEMBL3290 |
NA |
31 |
16 |
0.9049 |
0.8828 |
| 366 |
Ephrin type-B receptor 3 |
CHEMBL4901 |
NA |
48 |
18 |
0.9677 |
0.9856 |
| 367 |
Ephrin type-B receptor 4 |
CHEMBL5147 |
NA |
180 |
125 |
0.9627 |
0.9756 |
| 368 |
Epidermal growth factor receptor |
CHEMBL203 |
G719S |
5377 |
11 |
0.9722 |
0.9309 |
| 369 |
Epidermal growth factor receptor |
CHEMBL203 |
L861Q |
5377 |
12 |
0.9722 |
0.8705 |
| 370 |
Epidermal growth factor receptor |
CHEMBL203 |
G719C |
5377 |
13 |
0.9722 |
0.9272 |
| 371 |
Epidermal growth factor receptor |
CHEMBL203 |
C797S,L858R |
5377 |
15 |
0.9722 |
0.9852 |
| 372 |
Epidermal growth factor receptor |
CHEMBL203 |
T790M,C797S |
5377 |
21 |
0.9722 |
0.9988 |
| 373 |
Epidermal growth factor receptor |
CHEMBL203 |
T790M |
5377 |
33 |
0.9722 |
0.9762 |
| 374 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R |
5377 |
95 |
0.9722 |
0.9716 |
| 375 |
Epidermal growth factor receptor |
CHEMBL203 |
UNDEFINED MUTATION |
5377 |
191 |
0.9722 |
0.9843 |
| 376 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R,T790M,C797S |
5377 |
275 |
0.9722 |
0.9858 |
| 377 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R,T790M |
5377 |
326 |
0.9722 |
0.9885 |
| 378 |
Epidermal growth factor receptor |
CHEMBL203 |
NA |
5377 |
1784 |
0.9722 |
0.9752 |
| 379 |
Epithelial discoidin domain-containing receptor 1 |
CHEMBL5319 |
NA |
258 |
128 |
0.9578 |
0.9316 |
| 380 |
Epoxide hydrolase 1 |
CHEMBL1968 |
NA |
124 |
38 |
0.9967 |
1 |
| 381 |
Equilibrative nucleoside transporter 1 |
CHEMBL1997 |
NA |
148 |
25 |
0.9977 |
1 |
| 382 |
Estrogen receptor |
CHEMBL206 |
NA |
2436 |
959 |
0.9882 |
0.9914 |
| 383 |
Estrogen receptor beta |
CHEMBL242 |
NA |
1347 |
736 |
0.9915 |
0.9962 |
| 384 |
Estrogen-related receptor gamma |
CHEMBL4245 |
NA |
206 |
91 |
0.9979 |
0.9999 |
| 385 |
Eukaryotic elongation factor 2 kinase |
CHEMBL5026 |
NA |
44 |
13 |
0.9611 |
0.8819 |
| 386 |
Eukaryotic translation initiation factor 2 subunit 1 |
CHEMBL1255131 |
NA |
27 |
21 |
0.9967 |
0.9949 |
| 387 |
Eukaryotic translation initiation factor 2-alpha kinase 1 |
CHEMBL6029 |
NA |
29 |
23 |
0.9787 |
0.9996 |
| 388 |
Eukaryotic translation initiation factor 2-alpha kinase 3 |
CHEMBL6030 |
NA |
84 |
22 |
0.9993 |
0.9903 |
| 389 |
Eukaryotic translation initiation factor 4E |
CHEMBL4848 |
NA |
87 |
19 |
0.9715 |
0.9767 |
| 390 |
Extracellular calcium-sensing receptor |
CHEMBL1878 |
NA |
318 |
31 |
0.9998 |
0.9857 |
| 391 |
Farnesyl pyrophosphate synthase |
CHEMBL1782 |
NA |
199 |
42 |
0.9943 |
0.9902 |
| 392 |
Fatty acid synthase |
CHEMBL4158 |
NA |
177 |
117 |
0.9903 |
0.9924 |
| 393 |
Fatty acid-binding protein 5 |
CHEMBL3674 |
NA |
132 |
41 |
0.9935 |
0.9802 |
| 394 |
Fatty acid-binding protein, adipocyte |
CHEMBL2083 |
NA |
269 |
71 |
0.9918 |
0.9919 |
| 395 |
Fatty acid-binding protein, heart |
CHEMBL3344 |
NA |
76 |
32 |
0.9943 |
0.9982 |
| 396 |
Fatty acid-binding protein, liver |
CHEMBL5421 |
NA |
34 |
19 |
0.9671 |
0.9937 |
| 397 |
Fatty-acid amide hydrolase 1 |
CHEMBL2243 |
NA |
1169 |
411 |
0.9911 |
0.9961 |
| 398 |
Fibroblast growth factor 2 |
CHEMBL3107 |
NA |
23 |
18 |
1 |
1 |
| 399 |
Fibroblast growth factor receptor 1 |
CHEMBL3650 |
NA |
1094 |
677 |
0.9825 |
0.9814 |
| 400 |
Fibroblast growth factor receptor 2 |
CHEMBL4142 |
V564F |
381 |
20 |
0.9828 |
0.9999 |
| 401 |
Fibroblast growth factor receptor 2 |
CHEMBL4142 |
N549H |
381 |
40 |
0.9828 |
0.9917 |
| 402 |
Fibroblast growth factor receptor 2 |
CHEMBL4142 |
NA |
381 |
212 |
0.9828 |
0.9699 |
| 403 |
Fibroblast growth factor receptor 3 |
CHEMBL2742 |
K650M |
374 |
24 |
0.9844 |
0.9627 |
| 404 |
Fibroblast growth factor receptor 3 |
CHEMBL2742 |
V555M |
374 |
39 |
0.9844 |
0.9923 |
| 405 |
Fibroblast growth factor receptor 3 |
CHEMBL2742 |
NA |
374 |
165 |
0.9844 |
0.9648 |
| 406 |
Fibroblast growth factor receptor 4 |
CHEMBL3973 |
NA |
662 |
351 |
0.9908 |
0.9881 |
| 407 |
Flap endonuclease 1 |
CHEMBL5027 |
NA |
35 |
10 |
0.9994 |
0.9999 |
| 408 |
Focal adhesion kinase 1 |
CHEMBL2695 |
NA |
801 |
361 |
0.9789 |
0.9767 |
| 409 |
Free fatty acid receptor 1 |
CHEMBL4422 |
NA |
1577 |
69 |
0.9979 |
0.9996 |
| 410 |
Free fatty acid receptor 4 |
CHEMBL5339 |
NA |
432 |
12 |
0.999 |
0.9965 |
| 411 |
Fructose-1,6-bisphosphatase 1 |
CHEMBL3975 |
NA |
570 |
13 |
0.9942 |
0.9483 |
| 412 |
Furin |
CHEMBL2611 |
NA |
236 |
123 |
0.9943 |
0.9924 |
| 413 |
G protein-coupled receptor kinase 5 |
CHEMBL5678 |
NA |
164 |
74 |
0.9922 |
0.9842 |
| 414 |
G protein-coupled receptor kinase 6 |
CHEMBL6144 |
NA |
43 |
34 |
0.9674 |
0.9788 |
| 415 |
G-protein coupled bile acid receptor 1 |
CHEMBL5409 |
NA |
659 |
11 |
0.9924 |
0.9729 |
| 416 |
GTPase KRas |
CHEMBL2189121 |
G12V |
473 |
11 |
0.9861 |
1 |
| 417 |
GTPase KRas |
CHEMBL2189121 |
G12C,C51S,C80L,C118S |
473 |
12 |
0.9861 |
1 |
| 418 |
GTPase KRas |
CHEMBL2189121 |
G13D |
473 |
14 |
0.9861 |
1 |
| 419 |
GTPase KRas |
CHEMBL2189121 |
NA |
473 |
16 |
0.9861 |
0.9584 |
| 420 |
GTPase KRas |
CHEMBL2189121 |
G12C,C118A |
473 |
25 |
0.9861 |
1 |
| 421 |
GTPase KRas |
CHEMBL2189121 |
G12D |
473 |
40 |
0.9861 |
0.9952 |
| 422 |
GTPase KRas |
CHEMBL2189121 |
G12C |
473 |
77 |
0.9861 |
0.9986 |
| 423 |
Galactokinase |
CHEMBL1293257 |
NA |
75 |
18 |
1 |
1 |
| 424 |
Galanin receptor type 3 |
CHEMBL2731 |
NA |
23 |
23 |
1 |
1 |
| 425 |
Galectin-1 |
CHEMBL4915 |
NA |
84 |
24 |
0.9785 |
0.9999 |
| 426 |
Galectin-3 |
CHEMBL4531 |
NA |
228 |
110 |
0.9996 |
0.9994 |
| 427 |
Galectin-8 |
CHEMBL5475 |
NA |
78 |
11 |
0.9997 |
0.9997 |
| 428 |
Galectin-9 |
CHEMBL5474 |
NA |
51 |
23 |
0.9998 |
0.9998 |
| 429 |
Gamma-aminobutyric acid receptor subunit alpha-1 |
CHEMBL1962 |
NA |
76 |
69 |
0.9762 |
0.9814 |
| 430 |
Gamma-aminobutyric acid receptor subunit alpha-2 |
CHEMBL4956 |
NA |
51 |
50 |
0.971 |
0.9663 |
| 431 |
Gamma-aminobutyric acid receptor subunit alpha-3 |
CHEMBL3026 |
NA |
51 |
43 |
0.9649 |
0.9584 |
| 432 |
Gamma-aminobutyric acid receptor subunit alpha-5 |
CHEMBL5112 |
NA |
77 |
72 |
0.9833 |
0.986 |
| 433 |
Gastrin/cholecystokinin type B receptor |
CHEMBL298 |
NA |
227 |
69 |
0.9969 |
0.9896 |
| 434 |
Geranylgeranyl pyrophosphate synthase |
CHEMBL4769 |
NA |
148 |
18 |
0.9998 |
0.9999 |
| 435 |
Glucagon receptor |
CHEMBL1985 |
NA |
545 |
43 |
0.9963 |
0.9966 |
| 436 |
Glucagon-like peptide 1 receptor |
CHEMBL1784 |
NA |
203 |
13 |
0.9948 |
0.9558 |
| 437 |
Glucocorticoid receptor |
CHEMBL2034 |
NA |
1938 |
998 |
0.995 |
0.9988 |
| 438 |
Glucokinase regulatory protein |
CHEMBL1075152 |
NA |
71 |
50 |
1 |
1 |
| 439 |
Glucose-dependent insulinotropic receptor |
CHEMBL5652 |
NA |
1081 |
121 |
0.9972 |
1 |
| 440 |
Glutamate carboxypeptidase 2 |
CHEMBL1892 |
NA |
273 |
115 |
0.9963 |
0.9999 |
| 441 |
Glutamate receptor 2 |
CHEMBL4016 |
NA |
248 |
42 |
0.9968 |
0.9791 |
| 442 |
Glutamate receptor ionotropic, NMDA 2B |
CHEMBL1904 |
NA |
173 |
37 |
0.9787 |
0.9842 |
| 443 |
Glutamate receptor ionotropic, kainate 1 |
CHEMBL1918 |
NA |
94 |
41 |
0.9949 |
0.9902 |
| 444 |
Glutaminase kidney isoform, mitochondrial |
CHEMBL2146302 |
NA |
356 |
192 |
0.9947 |
1 |
| 445 |
Glutaminyl-peptide cyclotransferase |
CHEMBL4508 |
NA |
629 |
260 |
0.9978 |
0.9981 |
| 446 |
Glutaminyl-peptide cyclotransferase-like protein |
CHEMBL3638349 |
NA |
79 |
27 |
0.9889 |
0.9729 |
| 447 |
Glutathione S-transferase A1 |
CHEMBL3409 |
NA |
18 |
11 |
0.9641 |
0.9952 |
| 448 |
Glutathione S-transferase Mu 2 |
CHEMBL4589 |
NA |
64 |
53 |
0.9979 |
1 |
| 449 |
Glutathione S-transferase P |
CHEMBL3902 |
NA |
128 |
39 |
0.9905 |
0.9808 |
| 450 |
Glutathione S-transferase omega-1 |
CHEMBL3174 |
NA |
75 |
35 |
0.9562 |
0.9555 |
| 451 |
Glutathione reductase, mitochondrial |
CHEMBL2755 |
NA |
38 |
11 |
0.9614 |
0.821 |
| 452 |
Glycogen [starch] synthase, muscle |
CHEMBL4000 |
NA |
26 |
15 |
1 |
0.9911 |
| 453 |
Glycogen phosphorylase, liver form |
CHEMBL2568 |
NA |
373 |
109 |
0.9958 |
0.9926 |
| 454 |
Glycogen synthase kinase-3 alpha |
CHEMBL2850 |
UNDEFINED MUTATION |
254 |
24 |
0.9525 |
0.9641 |
| 455 |
Glycogen synthase kinase-3 alpha |
CHEMBL2850 |
NA |
254 |
151 |
0.9525 |
0.9491 |
| 456 |
Glycogen synthase kinase-3 beta |
CHEMBL262 |
NA |
2228 |
1189 |
0.9738 |
0.9754 |
| 457 |
Glycylpeptide N-tetradecanoyltransferase 1 |
CHEMBL2593 |
NA |
168 |
93 |
0.992 |
0.9844 |
| 458 |
Gonadotropin-releasing hormone receptor |
CHEMBL1855 |
NA |
679 |
260 |
0.9945 |
0.9956 |
| 459 |
Group 10 secretory phospholipase A2 |
CHEMBL4342 |
NA |
99 |
43 |
0.9954 |
0.9952 |
| 460 |
Group IIE secretory phospholipase A2 |
CHEMBL2154 |
NA |
15 |
13 |
1 |
1 |
| 461 |
Growth factor receptor-bound protein 2 |
CHEMBL3663 |
NA |
43 |
18 |
0.994 |
0.9965 |
| 462 |
Growth hormone secretagogue receptor type 1 |
CHEMBL4616 |
NA |
1003 |
162 |
0.9964 |
0.989 |
| 463 |
Heat shock protein 75 kDa, mitochondrial |
CHEMBL1075132 |
NA |
114 |
52 |
0.9954 |
0.9838 |
| 464 |
Heat shock protein HSP 90-alpha |
CHEMBL3880 |
NA |
913 |
565 |
0.9898 |
0.9947 |
| 465 |
Heat shock protein HSP 90-beta |
CHEMBL4303 |
NA |
466 |
226 |
0.9893 |
0.9878 |
| 466 |
Hematopoietic prostaglandin D synthase |
CHEMBL5879 |
NA |
247 |
58 |
0.9891 |
0.9937 |
| 467 |
Heparanase |
CHEMBL3921 |
NA |
201 |
63 |
0.9953 |
0.9841 |
| 468 |
Hepatocyte growth factor activator |
CHEMBL3351190 |
NA |
105 |
35 |
0.9989 |
0.997 |
| 469 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
Y1230H |
2745 |
13 |
0.9829 |
1 |
| 470 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
D1228V |
2745 |
19 |
0.9829 |
1 |
| 471 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
NA |
2745 |
2026 |
0.9829 |
0.9886 |
| 472 |
Hexokinase-4 |
CHEMBL3820 |
NA |
887 |
510 |
0.9975 |
0.9979 |
| 473 |
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A |
CHEMBL3012 |
NA |
277 |
84 |
0.9818 |
0.9945 |
| 474 |
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
CHEMBL3535 |
NA |
139 |
65 |
0.9658 |
0.944 |
| 475 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
G623R |
1330 |
12 |
0.9748 |
1 |
| 476 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
F589L |
1330 |
16 |
0.9748 |
1 |
| 477 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
G667C |
1330 |
50 |
0.9748 |
0.9984 |
| 478 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
G595R |
1330 |
81 |
0.9748 |
0.9992 |
| 479 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
NA |
1330 |
594 |
0.9748 |
0.9706 |
| 480 |
Histamine H1 receptor |
CHEMBL231 |
NA |
941 |
167 |
0.9805 |
0.9851 |
| 481 |
Histamine H2 receptor |
CHEMBL1941 |
NA |
280 |
22 |
0.9745 |
0.8634 |
| 482 |
Histamine H3 receptor |
CHEMBL264 |
NA |
2981 |
720 |
0.9916 |
0.9971 |
| 483 |
Histamine H4 receptor |
CHEMBL3759 |
NA |
830 |
224 |
0.9921 |
0.9997 |
| 484 |
Histone acetyltransferase KAT2A |
CHEMBL5501 |
NA |
38 |
11 |
0.9797 |
0.8997 |
| 485 |
Histone acetyltransferase KAT2B |
CHEMBL5500 |
NA |
153 |
59 |
0.9865 |
0.9956 |
| 486 |
Histone acetyltransferase KAT6A |
CHEMBL3774298 |
NA |
267 |
13 |
0.9984 |
0.9992 |
| 487 |
Histone acetyltransferase p300 |
CHEMBL3784 |
NA |
416 |
176 |
0.9714 |
0.975 |
| 488 |
Histone deacetylase 1 |
CHEMBL325 |
NA |
4485 |
2229 |
0.9924 |
0.9949 |
| 489 |
Histone deacetylase 11 |
CHEMBL3310 |
NA |
345 |
131 |
0.9923 |
0.9935 |
| 490 |
Histone deacetylase 2 |
CHEMBL1937 |
NA |
1666 |
801 |
0.9877 |
0.9901 |
| 491 |
Histone deacetylase 3 |
CHEMBL1829 |
NA |
1384 |
750 |
0.9913 |
0.9903 |
| 492 |
Histone deacetylase 4 |
CHEMBL3524 |
NA |
581 |
188 |
0.9914 |
0.9917 |
| 493 |
Histone deacetylase 5 |
CHEMBL2563 |
NA |
260 |
83 |
0.9824 |
0.9726 |
| 494 |
Histone deacetylase 6 |
CHEMBL1865 |
NA |
3396 |
1787 |
0.9906 |
0.9931 |
| 495 |
Histone deacetylase 7 |
CHEMBL2716 |
NA |
338 |
100 |
0.9839 |
0.9773 |
| 496 |
Histone deacetylase 8 |
CHEMBL3192 |
NA |
1772 |
635 |
0.991 |
0.9888 |
| 497 |
Histone deacetylase 9 |
CHEMBL4145 |
NA |
235 |
84 |
0.9821 |
0.9884 |
| 498 |
Histone-arginine methyltransferase CARM1 |
CHEMBL5406 |
NA |
280 |
160 |
0.9873 |
0.9985 |
| 499 |
Histone-lysine N-methyltransferase EHMT1 |
CHEMBL6031 |
NA |
179 |
41 |
0.9828 |
0.9593 |
| 500 |
Histone-lysine N-methyltransferase EHMT2 |
CHEMBL6032 |
NA |
525 |
228 |
0.9871 |
0.9971 |
| 501 |
Histone-lysine N-methyltransferase EZH1 |
CHEMBL2189116 |
NA |
50 |
33 |
0.9874 |
0.9994 |
| 502 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
Y641N |
638 |
23 |
0.9928 |
0.9995 |
| 503 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
A677G |
638 |
35 |
0.9928 |
0.9999 |
| 504 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
Y641F |
638 |
73 |
0.9928 |
0.9915 |
| 505 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
NA |
638 |
420 |
0.9928 |
0.9907 |
| 506 |
Histone-lysine N-methyltransferase NSD2 |
CHEMBL3108645 |
NA |
237 |
65 |
0.9688 |
0.992 |
| 507 |
Histone-lysine N-methyltransferase SETD2 |
CHEMBL3108647 |
NA |
28 |
25 |
0.9704 |
0.9672 |
| 508 |
Histone-lysine N-methyltransferase SMYD3 |
CHEMBL2321643 |
NA |
124 |
23 |
0.9884 |
0.9898 |
| 509 |
Histone-lysine N-methyltransferase, H3 lysine-79 specific |
CHEMBL1795117 |
NA |
158 |
58 |
0.9869 |
0.9775 |
| 510 |
Homeodomain-interacting protein kinase 1 |
CHEMBL5427 |
NA |
44 |
25 |
0.9141 |
0.8784 |
| 511 |
Homeodomain-interacting protein kinase 2 |
CHEMBL4576 |
NA |
37 |
34 |
0.8616 |
0.8572 |
| 512 |
Homeodomain-interacting protein kinase 3 |
CHEMBL4577 |
NA |
25 |
24 |
0.8503 |
0.8213 |
| 513 |
Hormone-sensitive lipase |
CHEMBL3590 |
NA |
64 |
23 |
0.9999 |
0.9999 |
| 514 |
Hydroxycarboxylic acid receptor 2 |
CHEMBL3785 |
NA |
467 |
78 |
0.9976 |
0.999 |
| 515 |
Hypoxanthine-guanine phosphoribosyltransferase |
CHEMBL2360 |
NA |
133 |
55 |
0.9923 |
0.9995 |
| 516 |
Immunoglobulin lambda variable 6-57 |
CHEMBL4739844 |
UNDEFINED MUTATION |
40 |
22 |
1 |
1 |
| 517 |
Inactive tyrosine-protein kinase transmembrane receptor ROR1 |
CHEMBL4665585 |
NA |
21 |
15 |
1 |
1 |
| 518 |
Indoleamine 2,3-dioxygenase 1 |
CHEMBL4685 |
NA |
2114 |
473 |
0.9823 |
0.9904 |
| 519 |
Indoleamine 2,3-dioxygenase 2 |
CHEMBL3627587 |
NA |
50 |
16 |
0.9812 |
1 |
| 520 |
Indolethylamine N-methyltransferase |
CHEMBL2131 |
NA |
29 |
14 |
0.97 |
1 |
| 521 |
Induced myeloid leukemia cell differentiation protein Mcl-1 |
CHEMBL4361 |
NA |
1220 |
393 |
0.9898 |
0.9914 |
| 522 |
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
CHEMBL3476 |
NA |
173 |
68 |
0.9789 |
0.9555 |
| 523 |
Inhibitor of nuclear factor kappa-B kinase subunit beta |
CHEMBL1991 |
NA |
601 |
312 |
0.9744 |
0.9901 |
| 524 |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon |
CHEMBL3529 |
NA |
131 |
29 |
0.9781 |
0.9506 |
| 525 |
Inosine-5'-monophosphate dehydrogenase 1 |
CHEMBL1822 |
NA |
122 |
61 |
0.9995 |
0.9995 |
| 526 |
Inosine-5'-monophosphate dehydrogenase 2 |
CHEMBL2002 |
NA |
239 |
168 |
0.9961 |
0.996 |
| 527 |
Inositol hexakisphosphate kinase 1 |
CHEMBL4523418 |
NA |
157 |
58 |
0.9999 |
0.9946 |
| 528 |
Inositol hexakisphosphate kinase 2 |
CHEMBL4523488 |
NA |
58 |
12 |
0.996 |
0.9557 |
| 529 |
Insulin receptor |
CHEMBL1981 |
NA |
275 |
133 |
0.9635 |
0.9624 |
| 530 |
Insulin-degrading enzyme |
CHEMBL1293287 |
NA |
49 |
17 |
0.908 |
0.9772 |
| 531 |
Insulin-like growth factor 1 receptor |
CHEMBL1957 |
NA |
645 |
268 |
0.9799 |
0.9787 |
| 532 |
Integrin alpha-4 |
CHEMBL278 |
NA |
117 |
17 |
0.9999 |
1 |
| 533 |
Integrin alpha-L |
CHEMBL1803 |
NA |
79 |
52 |
0.9817 |
1 |
| 534 |
Intercellular adhesion molecule 1 |
CHEMBL3070 |
NA |
39 |
30 |
0.9681 |
1 |
| 535 |
Interferon-induced, double-stranded RNA-activated protein kinase |
CHEMBL5785 |
NA |
89 |
47 |
0.9179 |
0.8573 |
| 536 |
Interleukin-1 receptor-associated kinase 1 |
CHEMBL3357 |
NA |
63 |
35 |
0.9176 |
0.8788 |
| 537 |
Interleukin-1 receptor-associated kinase 4 |
CHEMBL3778 |
NA |
907 |
567 |
0.9943 |
0.994 |
| 538 |
Interleukin-2 |
CHEMBL5880 |
NA |
81 |
23 |
0.9649 |
0.9455 |
| 539 |
Interleukin-8 |
CHEMBL2157 |
NA |
20 |
19 |
0.9574 |
0.9997 |
| 540 |
Intermediate conductance calcium-activated potassium channel protein 4 |
CHEMBL4305 |
NA |
47 |
14 |
0.9995 |
0.9998 |
| 541 |
Interstitial collagenase |
CHEMBL332 |
NA |
715 |
342 |
0.9873 |
0.9963 |
| 542 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
NA |
722 |
28 |
0.991 |
0.9634 |
| 543 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
R132C |
722 |
107 |
0.991 |
0.974 |
| 544 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
R132H |
722 |
267 |
0.991 |
0.9903 |
| 545 |
Isocitrate dehydrogenase [NADP], mitochondrial |
CHEMBL3991501 |
R172K |
103 |
25 |
0.9968 |
0.9921 |
| 546 |
Isocitrate dehydrogenase [NADP], mitochondrial |
CHEMBL3991501 |
R140Q |
103 |
60 |
0.9968 |
0.9973 |
| 547 |
Kallikrein-1 |
CHEMBL2319 |
NA |
87 |
41 |
0.9701 |
0.9729 |
| 548 |
Kallikrein-5 |
CHEMBL4447 |
NA |
112 |
10 |
0.9891 |
0.9761 |
| 549 |
Kallikrein-7 |
CHEMBL2443 |
NA |
138 |
45 |
0.9762 |
0.9951 |
| 550 |
Kappa-type opioid receptor |
CHEMBL237 |
NA |
2807 |
307 |
0.9829 |
0.9852 |
| 551 |
Kelch-like ECH-associated protein 1 |
CHEMBL2069156 |
NA |
358 |
81 |
0.9795 |
0.9943 |
| 552 |
Ketohexokinase |
CHEMBL1275212 |
NA |
76 |
33 |
0.9995 |
1 |
| 553 |
Kinesin-like protein KIF11 |
CHEMBL4581 |
NA |
716 |
264 |
0.9935 |
0.9989 |
| 554 |
Kinesin-like protein KIFC1 |
CHEMBL3351200 |
NA |
49 |
19 |
0.9936 |
0.9853 |
| 555 |
Kynurenine 3-monooxygenase |
CHEMBL2145 |
NA |
179 |
87 |
0.998 |
0.9985 |
| 556 |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial |
CHEMBL2046259 |
NA |
42 |
32 |
0.9745 |
0.9789 |
| 557 |
L-lactate dehydrogenase A chain |
CHEMBL4835 |
NA |
520 |
251 |
0.9776 |
0.9937 |
| 558 |
L-lactate dehydrogenase B chain |
CHEMBL4940 |
NA |
186 |
66 |
0.9925 |
0.9851 |
| 559 |
L-selectin |
CHEMBL3161 |
NA |
29 |
15 |
1 |
1 |
| 560 |
LIM domain kinase 1 |
CHEMBL3836 |
NA |
301 |
216 |
0.9703 |
0.9585 |
| 561 |
LIM domain kinase 2 |
CHEMBL5932 |
NA |
263 |
161 |
0.9719 |
0.9736 |
| 562 |
Lactoylglutathione lyase |
CHEMBL2424 |
NA |
146 |
41 |
0.9927 |
0.9913 |
| 563 |
Legumain |
CHEMBL4244 |
NA |
171 |
155 |
0.9998 |
0.9997 |
| 564 |
Lethal(3)malignant brain tumor-like protein 1 |
CHEMBL1287622 |
NA |
79 |
29 |
0.9788 |
0.9525 |
| 565 |
Lethal(3)malignant brain tumor-like protein 3 |
CHEMBL1287623 |
NA |
88 |
58 |
1 |
1 |
| 566 |
Leucine-rich repeat serine/threonine-protein kinase 2 |
CHEMBL1075104 |
NA |
984 |
444 |
0.9876 |
0.9858 |
| 567 |
Leucine-rich repeat serine/threonine-protein kinase 2 |
CHEMBL1075104 |
G2019S |
984 |
461 |
0.9876 |
0.9884 |
| 568 |
Leukocyte tyrosine kinase receptor |
CHEMBL5627 |
NA |
41 |
21 |
0.9266 |
0.7936 |
| 569 |
Leukotriene A-4 hydrolase |
CHEMBL4618 |
NA |
311 |
151 |
0.9961 |
0.9989 |
| 570 |
Leukotriene B4 receptor 1 |
CHEMBL3911 |
NA |
26 |
20 |
0.9388 |
0.9699 |
| 571 |
Leukotriene C4 synthase |
CHEMBL1743183 |
NA |
47 |
29 |
0.9907 |
0.9999 |
| 572 |
Liver carboxylesterase 1 |
CHEMBL2265 |
NA |
169 |
54 |
0.9909 |
0.9864 |
| 573 |
Lon protease homolog, mitochondrial |
CHEMBL4879436 |
NA |
23 |
21 |
0.9998 |
0.9997 |
| 574 |
Long-chain fatty acid transport protein 1 |
CHEMBL2052038 |
NA |
36 |
32 |
1 |
1 |
| 575 |
Long-chain-fatty-acid--CoA ligase 1 |
CHEMBL4295746 |
NA |
29 |
19 |
0.9808 |
0.9738 |
| 576 |
Low molecular weight phosphotyrosine protein phosphatase |
CHEMBL4903 |
NA |
158 |
29 |
0.9933 |
0.9717 |
| 577 |
Lymphokine-activated killer T-cell-originated protein kinase |
CHEMBL4896 |
NA |
38 |
30 |
0.9482 |
0.9636 |
| 578 |
Lysine--tRNA ligase |
CHEMBL5575 |
NA |
68 |
44 |
0.9725 |
0.9741 |
| 579 |
Lysine-specific demethylase 2A |
CHEMBL1938210 |
NA |
100 |
26 |
0.9889 |
0.9979 |
| 580 |
Lysine-specific demethylase 3A |
CHEMBL1938209 |
NA |
60 |
25 |
0.9969 |
0.9866 |
| 581 |
Lysine-specific demethylase 4A |
CHEMBL5896 |
NA |
182 |
25 |
0.978 |
0.9682 |
| 582 |
Lysine-specific demethylase 4C |
CHEMBL6175 |
NA |
226 |
66 |
0.9861 |
0.9936 |
| 583 |
Lysine-specific demethylase 4D |
CHEMBL6138 |
NA |
97 |
17 |
0.992 |
0.9645 |
| 584 |
Lysine-specific demethylase 4E |
CHEMBL1293226 |
NA |
91 |
31 |
0.9839 |
0.9917 |
| 585 |
Lysine-specific demethylase 5A |
CHEMBL2424504 |
NA |
219 |
111 |
0.9841 |
0.997 |
| 586 |
Lysine-specific demethylase 5B |
CHEMBL3774295 |
NA |
290 |
174 |
0.9954 |
0.9973 |
| 587 |
Lysine-specific demethylase 5C |
CHEMBL2163176 |
NA |
161 |
92 |
0.9898 |
0.9948 |
| 588 |
Lysine-specific demethylase 6B |
CHEMBL1938211 |
NA |
117 |
44 |
0.9856 |
0.9985 |
| 589 |
Lysine-specific histone demethylase 1A |
CHEMBL6136 |
NA |
1407 |
454 |
0.9801 |
0.9807 |
| 590 |
Lysine-specific histone demethylase 2 |
CHEMBL1938208 |
NA |
62 |
20 |
0.9883 |
0.9705 |
| 591 |
Lysophosphatidic acid receptor 1 |
CHEMBL3819 |
NA |
268 |
16 |
0.9962 |
0.9999 |
| 592 |
Lysophosphatidic acid receptor 3 |
CHEMBL3250 |
NA |
60 |
10 |
0.9763 |
1 |
| 593 |
Lysosomal Pro-X carboxypeptidase |
CHEMBL2335 |
NA |
291 |
261 |
0.9975 |
0.9997 |
| 594 |
Lysosomal acid glucosylceramidase |
CHEMBL2179 |
NA |
277 |
83 |
0.9957 |
0.9981 |
| 595 |
Lysosomal alpha-glucosidase |
CHEMBL2608 |
NA |
63 |
31 |
0.9815 |
0.9957 |
| 596 |
M-phase inducer phosphatase 1 |
CHEMBL3775 |
NA |
204 |
66 |
0.9907 |
0.9913 |
| 597 |
M-phase inducer phosphatase 2 |
CHEMBL4804 |
NA |
309 |
87 |
0.987 |
0.98 |
| 598 |
M-phase inducer phosphatase 3 |
CHEMBL2378 |
NA |
89 |
25 |
0.9935 |
0.9902 |
| 599 |
MAP kinase-activated protein kinase 2 |
CHEMBL2208 |
NA |
547 |
261 |
0.9883 |
0.9924 |
| 600 |
MAP kinase-interacting serine/threonine-protein kinase 1 |
CHEMBL4718 |
NA |
442 |
160 |
0.9808 |
0.9719 |
| 601 |
MAP kinase-interacting serine/threonine-protein kinase 2 |
CHEMBL4204 |
NA |
412 |
166 |
0.9792 |
0.98 |
| 602 |
MAP/microtubule affinity-regulating kinase 3 |
CHEMBL5600 |
NA |
73 |
27 |
0.9722 |
0.9122 |
| 603 |
Macrophage colony-stimulating factor 1 receptor |
CHEMBL1844 |
NA |
872 |
607 |
0.98 |
0.9783 |
| 604 |
Macrophage metalloelastase |
CHEMBL4393 |
NA |
383 |
242 |
0.9913 |
0.9889 |
| 605 |
Macrophage migration inhibitory factor |
CHEMBL2085 |
NA |
291 |
99 |
0.9692 |
0.9558 |
| 606 |
Macrophage-stimulating protein receptor |
CHEMBL2689 |
NA |
103 |
51 |
0.9722 |
0.9632 |
| 607 |
Malate dehydrogenase, mitochondrial |
CHEMBL5917 |
NA |
27 |
15 |
0.984 |
0.9888 |
| 608 |
Malonyl-CoA decarboxylase, mitochondrial |
CHEMBL4698 |
NA |
250 |
197 |
1 |
1 |
| 609 |
Maltase-glucoamylase |
CHEMBL2074 |
NA |
206 |
109 |
0.9853 |
0.9928 |
| 610 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
V559D,V654A |
797 |
17 |
0.972 |
0.8435 |
| 611 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
V559D |
797 |
20 |
0.972 |
0.9001 |
| 612 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
V654A |
797 |
28 |
0.972 |
0.9487 |
| 613 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
V559D,T670I |
797 |
29 |
0.972 |
0.9482 |
| 614 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
D816V |
797 |
56 |
0.972 |
0.9418 |
| 615 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
NA |
797 |
445 |
0.972 |
0.9663 |
| 616 |
Maternal embryonic leucine zipper kinase |
CHEMBL4578 |
NA |
131 |
54 |
0.9411 |
0.921 |
| 617 |
Matrilysin |
CHEMBL4073 |
NA |
249 |
147 |
0.9876 |
0.9944 |
| 618 |
Matrix metalloproteinase-14 |
CHEMBL3869 |
NA |
505 |
239 |
0.9894 |
0.9959 |
| 619 |
Matrix metalloproteinase-16 |
CHEMBL2200 |
NA |
32 |
13 |
0.9967 |
0.9986 |
| 620 |
Matrix metalloproteinase-9 |
CHEMBL321 |
NA |
1176 |
751 |
0.9774 |
0.9907 |
| 621 |
Melanin-concentrating hormone receptor 1 |
CHEMBL344 |
NA |
2557 |
466 |
0.9929 |
0.9987 |
| 622 |
Melanocortin receptor 3 |
CHEMBL4644 |
NA |
484 |
42 |
0.995 |
0.9807 |
| 623 |
Melanocortin receptor 4 |
CHEMBL259 |
NA |
1704 |
254 |
0.9974 |
0.9957 |
| 624 |
Melanocortin receptor 5 |
CHEMBL4608 |
NA |
330 |
35 |
0.9958 |
0.9984 |
| 625 |
Melanocyte-stimulating hormone receptor |
CHEMBL3795 |
NA |
417 |
21 |
0.9963 |
0.9992 |
| 626 |
Melatonin receptor type 1A |
CHEMBL1945 |
NA |
625 |
27 |
0.9941 |
0.9607 |
| 627 |
Melatonin receptor type 1B |
CHEMBL1946 |
NA |
675 |
83 |
0.9955 |
0.9983 |
| 628 |
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase |
CHEMBL3984 |
NA |
75 |
12 |
0.9956 |
0.9963 |
| 629 |
Menin |
CHEMBL1615381 |
NA |
166 |
92 |
0.9928 |
0.9958 |
| 630 |
Metabotropic glutamate receptor 1 |
CHEMBL3772 |
NA |
436 |
64 |
0.9925 |
0.9985 |
| 631 |
Metabotropic glutamate receptor 2 |
CHEMBL5137 |
NA |
819 |
67 |
0.9962 |
0.9864 |
| 632 |
Metabotropic glutamate receptor 4 |
CHEMBL2736 |
NA |
500 |
48 |
0.9962 |
0.9962 |
| 633 |
Metabotropic glutamate receptor 5 |
CHEMBL3227 |
NA |
1445 |
95 |
0.9945 |
0.9926 |
| 634 |
Methionine aminopeptidase 1 |
CHEMBL2474 |
NA |
145 |
41 |
0.9956 |
0.9824 |
| 635 |
Methionine aminopeptidase 2 |
CHEMBL3922 |
NA |
411 |
298 |
0.9985 |
0.9992 |
| 636 |
Microtubule-associated protein 2 |
CHEMBL2390810 |
NA |
39 |
21 |
1 |
1 |
| 637 |
Microtubule-associated protein tau |
CHEMBL1293224 |
NA |
232 |
77 |
0.9892 |
0.9828 |
| 638 |
Microtubule-associated proteins 1A/1B light chain 3B |
CHEMBL4879514 |
NA |
89 |
40 |
0.9997 |
0.9998 |
| 639 |
Mineralocorticoid receptor |
CHEMBL1994 |
NA |
586 |
250 |
0.9971 |
0.9989 |
| 640 |
Mitogen-activated protein kinase 1 |
CHEMBL4040 |
NA |
662 |
356 |
0.9688 |
0.986 |
| 641 |
Mitogen-activated protein kinase 10 |
CHEMBL2637 |
NA |
690 |
473 |
0.9836 |
0.9828 |
| 642 |
Mitogen-activated protein kinase 11 |
CHEMBL3961 |
NA |
143 |
51 |
0.9825 |
0.9422 |
| 643 |
Mitogen-activated protein kinase 12 |
CHEMBL4674 |
NA |
38 |
22 |
0.9704 |
0.956 |
| 644 |
Mitogen-activated protein kinase 14 |
CHEMBL260 |
NA |
2452 |
1539 |
0.988 |
0.9917 |
| 645 |
Mitogen-activated protein kinase 15 |
CHEMBL5198 |
NA |
22 |
15 |
0.8019 |
0.7248 |
| 646 |
Mitogen-activated protein kinase 3 |
CHEMBL3385 |
NA |
129 |
78 |
0.9395 |
0.9526 |
| 647 |
Mitogen-activated protein kinase 6 |
CHEMBL5121 |
NA |
23 |
10 |
0.9496 |
0.8601 |
| 648 |
Mitogen-activated protein kinase 7 |
CHEMBL5332 |
NA |
140 |
39 |
0.9819 |
0.9562 |
| 649 |
Mitogen-activated protein kinase 8 |
CHEMBL2276 |
NA |
761 |
414 |
0.9831 |
0.9845 |
| 650 |
Mitogen-activated protein kinase 9 |
CHEMBL4179 |
NA |
409 |
242 |
0.9689 |
0.9716 |
| 651 |
Mitogen-activated protein kinase kinase kinase 11 |
CHEMBL2708 |
NA |
66 |
44 |
0.9658 |
0.9165 |
| 652 |
Mitogen-activated protein kinase kinase kinase 12 |
CHEMBL1908389 |
NA |
105 |
47 |
0.993 |
0.9858 |
| 653 |
Mitogen-activated protein kinase kinase kinase 14 |
CHEMBL5888 |
NA |
269 |
112 |
0.9985 |
0.9991 |
| 654 |
Mitogen-activated protein kinase kinase kinase 20 |
CHEMBL3886 |
NA |
88 |
30 |
0.9408 |
0.94 |
| 655 |
Mitogen-activated protein kinase kinase kinase 5 |
CHEMBL5285 |
NA |
347 |
203 |
0.9942 |
0.99 |
| 656 |
Mitogen-activated protein kinase kinase kinase 7 |
CHEMBL5776 |
NA |
204 |
75 |
0.9837 |
0.9704 |
| 657 |
Mitogen-activated protein kinase kinase kinase 8 |
CHEMBL4899 |
NA |
137 |
85 |
0.9896 |
1 |
| 658 |
Mitogen-activated protein kinase kinase kinase 9 |
CHEMBL2872 |
NA |
66 |
37 |
0.9114 |
0.8779 |
| 659 |
Mitogen-activated protein kinase kinase kinase kinase 1 |
CHEMBL5749 |
NA |
480 |
266 |
0.9877 |
0.9815 |
| 660 |
Mitogen-activated protein kinase kinase kinase kinase 2 |
CHEMBL5330 |
NA |
81 |
65 |
0.9658 |
0.9619 |
| 661 |
Mitogen-activated protein kinase kinase kinase kinase 3 |
CHEMBL5432 |
NA |
100 |
82 |
0.9668 |
0.9663 |
| 662 |
Mitogen-activated protein kinase kinase kinase kinase 4 |
CHEMBL6166 |
NA |
186 |
75 |
0.9606 |
0.9687 |
| 663 |
Mitogen-activated protein kinase kinase kinase kinase 5 |
CHEMBL4852 |
NA |
37 |
20 |
0.9011 |
0.8094 |
| 664 |
Monoacylglycerol lipase ABHD6 |
CHEMBL2189127 |
NA |
83 |
17 |
0.9678 |
0.992 |
| 665 |
Monocarboxylate transporter 1 |
CHEMBL4360 |
NA |
86 |
35 |
0.9789 |
0.9799 |
| 666 |
Monocarboxylate transporter 4 |
CHEMBL2073663 |
NA |
104 |
20 |
0.9836 |
1 |
| 667 |
Monoglyceride lipase |
CHEMBL4191 |
NA |
906 |
354 |
0.9926 |
0.9964 |
| 668 |
Motilin receptor |
CHEMBL2203 |
NA |
184 |
21 |
0.9925 |
0.9437 |
| 669 |
Mu-type opioid receptor |
CHEMBL233 |
NA |
3321 |
343 |
0.9841 |
0.9905 |
| 670 |
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
CHEMBL3632452 |
NA |
349 |
119 |
0.9934 |
0.9952 |
| 671 |
Muscarinic acetylcholine receptor M1 |
CHEMBL216 |
NA |
1285 |
92 |
0.9811 |
0.9582 |
| 672 |
Muscarinic acetylcholine receptor M2 |
CHEMBL211 |
NA |
666 |
72 |
0.9714 |
0.9553 |
| 673 |
Muscarinic acetylcholine receptor M3 |
CHEMBL245 |
NA |
970 |
144 |
0.985 |
0.9628 |
| 674 |
Muscarinic acetylcholine receptor M4 |
CHEMBL1821 |
NA |
948 |
34 |
0.9881 |
0.9266 |
| 675 |
Muscarinic acetylcholine receptor M5 |
CHEMBL2035 |
NA |
562 |
24 |
0.9785 |
0.8401 |
| 676 |
Muscle, skeletal receptor tyrosine-protein kinase |
CHEMBL5684 |
NA |
20 |
13 |
0.8469 |
0.7925 |
| 677 |
Myc proto-oncogene protein |
CHEMBL1250348 |
NA |
53 |
10 |
0.9756 |
1 |
| 678 |
Myelin transcription factor 1 |
CHEMBL2331044 |
NA |
32 |
30 |
0.9478 |
0.9452 |
| 679 |
Myeloperoxidase |
CHEMBL2439 |
NA |
303 |
191 |
0.9794 |
0.99 |
| 680 |
Myosin light chain kinase 2, skeletal/cardiac muscle |
CHEMBL2777 |
NA |
23 |
13 |
0.8786 |
0.7948 |
| 681 |
Myosin light chain kinase family member 4 |
CHEMBL5426 |
NA |
21 |
18 |
0.9203 |
0.9722 |
| 682 |
Myosin light chain kinase, smooth muscle |
CHEMBL2428 |
NA |
51 |
30 |
0.8905 |
0.8661 |
| 683 |
N-acetylated-alpha-linked acidic dipeptidase 2 |
CHEMBL2609 |
NA |
29 |
23 |
1 |
1 |
| 684 |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 |
CHEMBL5465363 |
NA |
39 |
35 |
1 |
1 |
| 685 |
N-acylethanolamine-hydrolyzing acid amidase |
CHEMBL4349 |
NA |
217 |
96 |
0.9965 |
0.9976 |
| 686 |
N-lysine methyltransferase SMYD2 |
CHEMBL2169716 |
NA |
113 |
31 |
0.9973 |
0.968 |
| 687 |
NACHT, LRR and PYD domains-containing protein 3 |
CHEMBL1741208 |
NA |
541 |
23 |
0.9926 |
0.9404 |
| 688 |
NAD(P)H dehydrogenase [quinone] 1 |
CHEMBL3623 |
NA |
134 |
49 |
0.9729 |
0.9974 |
| 689 |
NAD-dependent malic enzyme, mitochondrial |
CHEMBL5291602 |
NA |
30 |
16 |
0.9661 |
0.9126 |
| 690 |
NAD-dependent protein deacetylase sirtuin-1 |
CHEMBL4506 |
NA |
566 |
106 |
0.9801 |
0.9611 |
| 691 |
NAD-dependent protein deacetylase sirtuin-2 |
CHEMBL4462 |
NA |
764 |
181 |
0.9818 |
0.9626 |
| 692 |
NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
CHEMBL4461 |
NA |
252 |
60 |
0.9812 |
0.9835 |
| 693 |
NAD-dependent protein deacylase sirtuin-5, mitochondrial |
CHEMBL2163183 |
NA |
284 |
130 |
0.9882 |
0.9861 |
| 694 |
NAD-dependent protein deacylase sirtuin-6 |
CHEMBL2163182 |
NA |
60 |
16 |
0.9507 |
0.9015 |
| 695 |
NADP-dependent malic enzyme |
CHEMBL3495 |
NA |
34 |
16 |
0.9934 |
0.9644 |
| 696 |
NADP-dependent malic enzyme, mitochondrial |
CHEMBL6182 |
NA |
31 |
28 |
0.995 |
0.9996 |
| 697 |
NT-3 growth factor receptor |
CHEMBL5608 |
NA |
317 |
194 |
0.9791 |
0.9626 |
| 698 |
NUAK family SNF1-like kinase 1 |
CHEMBL5784 |
NA |
74 |
32 |
0.9295 |
0.9206 |
| 699 |
NUAK family SNF1-like kinase 2 |
CHEMBL5698 |
NA |
25 |
14 |
0.8424 |
0.8465 |
| 700 |
Neprilysin |
CHEMBL1944 |
NA |
203 |
129 |
0.9935 |
0.9991 |
| 701 |
Neuromedin-K receptor |
CHEMBL4429 |
NA |
329 |
22 |
0.9956 |
0.9484 |
| 702 |
Neuronal acetylcholine receptor subunit alpha-7 |
CHEMBL2492 |
NA |
719 |
29 |
0.9832 |
0.9982 |
| 703 |
Neuropeptide Y receptor type 2 |
CHEMBL4018 |
NA |
164 |
60 |
0.9827 |
0.9659 |
| 704 |
Neuropeptide Y receptor type 5 |
CHEMBL4561 |
NA |
449 |
122 |
0.9952 |
0.9993 |
| 705 |
Neuropilin-1 |
CHEMBL5174 |
NA |
101 |
36 |
0.9936 |
0.9846 |
| 706 |
Neurotensin receptor type 1 |
CHEMBL4123 |
NA |
180 |
26 |
0.9952 |
0.9839 |
| 707 |
Neutrophil collagenase |
CHEMBL4588 |
NA |
461 |
282 |
0.9867 |
0.9938 |
| 708 |
Neutrophil elastase |
CHEMBL248 |
NA |
670 |
408 |
0.9808 |
0.9933 |
| 709 |
Nicotinamide N-methyltransferase |
CHEMBL2346486 |
NA |
180 |
49 |
0.9951 |
0.9993 |
| 710 |
Nicotinamide phosphoribosyltransferase |
CHEMBL1744525 |
NA |
753 |
391 |
0.9947 |
0.9972 |
| 711 |
Nitric oxide synthase 1 |
CHEMBL3568 |
NA |
413 |
81 |
0.9976 |
0.9971 |
| 712 |
Nitric oxide synthase 3 |
CHEMBL4803 |
NA |
239 |
77 |
0.999 |
0.9981 |
| 713 |
Nitric oxide synthase, inducible |
CHEMBL4481 |
NA |
412 |
107 |
0.9918 |
0.9955 |
| 714 |
Nociceptin receptor |
CHEMBL2014 |
NA |
1098 |
107 |
0.9954 |
0.9962 |
| 715 |
Non-receptor tyrosine-protein kinase TNK1 |
CHEMBL5334 |
NA |
20 |
11 |
0.9224 |
0.8055 |
| 716 |
Non-receptor tyrosine-protein kinase TYK2 |
CHEMBL3553 |
NA |
1108 |
723 |
0.9876 |
0.9864 |
| 717 |
Nuclear receptor ROR-alpha |
CHEMBL5868 |
NA |
106 |
17 |
0.9826 |
0.9598 |
| 718 |
Nuclear receptor ROR-beta |
CHEMBL3091268 |
NA |
218 |
39 |
0.9971 |
0.992 |
| 719 |
Nuclear receptor ROR-gamma |
CHEMBL1741186 |
NA |
2408 |
922 |
0.9914 |
0.996 |
| 720 |
Nuclear receptor subfamily 1 group D member 1 |
CHEMBL1961783 |
NA |
90 |
28 |
0.9937 |
0.9867 |
| 721 |
Nuclear receptor subfamily 1 group I member 2 |
CHEMBL3401 |
NA |
402 |
99 |
0.9736 |
0.9728 |
| 722 |
Nuclear receptor subfamily 1 group I member 3 |
CHEMBL5503 |
NA |
160 |
65 |
0.9954 |
0.9988 |
| 723 |
Nuclear receptor subfamily 4 group A member 2 |
CHEMBL5002 |
NA |
157 |
12 |
0.9878 |
0.9169 |
| 724 |
Nuclear receptor subfamily 5 group A member 2 |
CHEMBL3544 |
NA |
70 |
16 |
0.9898 |
1 |
| 725 |
Nucleic acid dioxygenase ALKBH1 |
CHEMBL5169151 |
NA |
47 |
40 |
1 |
1 |
| 726 |
Nucleosome-remodeling factor subunit BPTF |
CHEMBL3085621 |
NA |
68 |
10 |
0.9542 |
0.9656 |
| 727 |
Orexin receptor type 2 |
CHEMBL4792 |
NA |
1120 |
180 |
0.993 |
0.9939 |
| 728 |
Orexin/Hypocretin receptor type 1 |
CHEMBL5113 |
NA |
960 |
155 |
0.9891 |
0.9935 |
| 729 |
Oxidized purine nucleoside triphosphate hydrolase |
CHEMBL3708265 |
NA |
139 |
52 |
0.994 |
0.9887 |
| 730 |
Oxysterols receptor LXR-alpha |
CHEMBL2808 |
NA |
677 |
266 |
0.9927 |
0.993 |
| 731 |
Oxysterols receptor LXR-beta |
CHEMBL4093 |
NA |
755 |
284 |
0.9912 |
0.9966 |
| 732 |
Oxytocin receptor |
CHEMBL2049 |
NA |
572 |
127 |
0.9936 |
0.9938 |
| 733 |
P-selectin |
CHEMBL5378 |
NA |
58 |
19 |
0.9949 |
0.9864 |
| 734 |
P2X purinoceptor 3 |
CHEMBL2998 |
NA |
332 |
38 |
0.9687 |
0.9552 |
| 735 |
P2X purinoceptor 7 |
CHEMBL4805 |
NA |
1072 |
94 |
0.9912 |
0.9746 |
| 736 |
P2Y purinoceptor 1 |
CHEMBL4315 |
NA |
371 |
48 |
0.9933 |
0.9989 |
| 737 |
P2Y purinoceptor 12 |
CHEMBL2001 |
NA |
961 |
48 |
0.9968 |
0.9699 |
| 738 |
Palmitoleoyl-protein carboxylesterase NOTUM |
CHEMBL3714531 |
NA |
444 |
50 |
0.9977 |
0.9979 |
| 739 |
Pancreatic triacylglycerol lipase |
CHEMBL1812 |
NA |
60 |
35 |
0.9846 |
0.9864 |
| 740 |
Pantetheinase |
CHEMBL4739843 |
NA |
32 |
15 |
1 |
1 |
| 741 |
Pantothenate kinase 3 |
CHEMBL3407328 |
NA |
83 |
35 |
0.9866 |
0.9925 |
| 742 |
Pepsin A |
CHEMBL3295 |
NA |
12 |
10 |
0.9751 |
1 |
| 743 |
Peptidyl-prolyl cis-trans isomerase A |
CHEMBL1949 |
NA |
134 |
56 |
0.9965 |
0.9935 |
| 744 |
Peptidyl-prolyl cis-trans isomerase D |
CHEMBL1697657 |
NA |
35 |
13 |
0.9182 |
0.7452 |
| 745 |
Peptidyl-prolyl cis-trans isomerase FKBP1A |
CHEMBL1902 |
NA |
306 |
152 |
0.9917 |
0.9936 |
| 746 |
Peptidyl-prolyl cis-trans isomerase FKBP4 |
CHEMBL4050 |
NA |
86 |
27 |
0.99 |
0.9607 |
| 747 |
Peptidyl-prolyl cis-trans isomerase FKBP5 |
CHEMBL2052031 |
NA |
180 |
68 |
0.9899 |
0.9852 |
| 748 |
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
CHEMBL2288 |
NA |
372 |
140 |
0.9869 |
0.9804 |
| 749 |
Peregrin |
CHEMBL3132741 |
NA |
204 |
45 |
0.9772 |
0.9981 |
| 750 |
Peroxiredoxin-1 |
CHEMBL5315 |
NA |
40 |
31 |
0.9738 |
0.9715 |
| 751 |
Peroxisome proliferator-activated receptor alpha |
CHEMBL239 |
NA |
1996 |
370 |
0.993 |
0.9957 |
| 752 |
Peroxisome proliferator-activated receptor delta |
CHEMBL3979 |
NA |
1357 |
351 |
0.995 |
0.9986 |
| 753 |
Peroxisome proliferator-activated receptor gamma |
CHEMBL235 |
NA |
2821 |
701 |
0.984 |
0.9946 |
| 754 |
Phenylethanolamine N-methyltransferase |
CHEMBL4617 |
NA |
140 |
42 |
0.9994 |
0.9996 |
| 755 |
Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
CHEMBL3112379 |
NA |
105 |
18 |
0.9933 |
0.9633 |
| 756 |
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 |
CHEMBL2331064 |
NA |
46 |
17 |
0.9947 |
0.9764 |
| 757 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 |
CHEMBL1075165 |
NA |
174 |
88 |
0.9517 |
0.9422 |
| 758 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
CHEMBL4005 |
H1047R |
3027 |
21 |
0.9832 |
0.9608 |
| 759 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
CHEMBL4005 |
NA |
3027 |
1800 |
0.9832 |
0.9866 |
| 760 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
CHEMBL3145 |
NA |
1326 |
604 |
0.9829 |
0.9838 |
| 761 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
CHEMBL3130 |
NA |
2459 |
1555 |
0.9872 |
0.9889 |
| 762 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
CHEMBL3267 |
NA |
2045 |
1128 |
0.9821 |
0.9849 |
| 763 |
Phosphatidylinositol 4-kinase alpha |
CHEMBL3667 |
NA |
92 |
53 |
0.983 |
0.982 |
| 764 |
Phosphatidylinositol 4-kinase beta |
CHEMBL3268 |
NA |
235 |
98 |
0.9771 |
0.9738 |
| 765 |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha |
CHEMBL1075102 |
NA |
68 |
41 |
0.98 |
0.9465 |
| 766 |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
CHEMBL5554 |
NA |
65 |
24 |
0.9628 |
0.9098 |
| 767 |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
CHEMBL1908383 |
NA |
83 |
27 |
0.9858 |
0.9871 |
| 768 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
CHEMBL1795194 |
NA |
178 |
29 |
0.978 |
0.9435 |
| 769 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
CHEMBL5667 |
NA |
48 |
21 |
0.969 |
0.92 |
| 770 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
CHEMBL1770034 |
NA |
80 |
30 |
0.9937 |
0.9761 |
| 771 |
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
CHEMBL2911 |
NA |
21 |
11 |
1 |
1 |
| 772 |
Phosphoglycerate mutase 1 |
CHEMBL3334418 |
NA |
65 |
22 |
0.9857 |
0.9522 |
| 773 |
Phospholipase A2 group V |
CHEMBL4323 |
NA |
44 |
16 |
0.9997 |
0.999 |
| 774 |
Phospholipase A2, membrane associated |
CHEMBL3474 |
NA |
180 |
76 |
0.9766 |
0.9646 |
| 775 |
Phospholipase D1 |
CHEMBL2536 |
NA |
148 |
21 |
0.9944 |
0.9976 |
| 776 |
Phospholipase D2 |
CHEMBL2734 |
NA |
120 |
17 |
0.9937 |
0.9974 |
| 777 |
Phospholipid hydroperoxide glutathione peroxidase GPX4 |
CHEMBL4295754 |
NA |
101 |
42 |
0.991 |
0.9999 |
| 778 |
Plasma kallikrein |
CHEMBL2000 |
NA |
440 |
215 |
0.98 |
0.9862 |
| 779 |
Plasminogen |
CHEMBL1801 |
NA |
337 |
113 |
0.9844 |
0.993 |
| 780 |
Plasminogen activator inhibitor 1 |
CHEMBL3475 |
NA |
87 |
33 |
0.9863 |
0.9844 |
| 781 |
Platelet-activating factor acetylhydrolase |
CHEMBL3514 |
NA |
194 |
107 |
0.9965 |
0.9974 |
| 782 |
Platelet-derived growth factor receptor alpha |
CHEMBL2007 |
NA |
431 |
251 |
0.9711 |
0.9627 |
| 783 |
Platelet-derived growth factor receptor beta |
CHEMBL1913 |
NA |
656 |
308 |
0.9747 |
0.9639 |
| 784 |
Poly [ADP-ribose] polymerase 1 |
CHEMBL3105 |
NA |
2152 |
1312 |
0.9907 |
0.9925 |
| 785 |
Poly [ADP-ribose] polymerase 2 |
CHEMBL5366 |
NA |
457 |
171 |
0.9919 |
0.9897 |
| 786 |
Poly [ADP-ribose] polymerase tankyrase-1 |
CHEMBL6164 |
NA |
483 |
257 |
0.9897 |
0.9873 |
| 787 |
Poly [ADP-ribose] polymerase tankyrase-2 |
CHEMBL6154 |
NA |
512 |
249 |
0.9889 |
0.9869 |
| 788 |
Poly(ADP-ribose) glycohydrolase |
CHEMBL1795143 |
NA |
110 |
41 |
1 |
1 |
| 789 |
Polyamine deacetylase HDAC10 |
CHEMBL5103 |
NA |
311 |
160 |
0.991 |
0.9911 |
| 790 |
Polycomb complex protein BMI-1 |
CHEMBL4295749 |
NA |
25 |
25 |
1 |
1 |
| 791 |
Polycomb protein EED |
CHEMBL2189117 |
NA |
318 |
165 |
0.9887 |
0.9989 |
| 792 |
Polyunsaturated fatty acid 5-lipoxygenase |
CHEMBL215 |
NA |
1405 |
275 |
0.9753 |
0.987 |
| 793 |
Polyunsaturated fatty acid lipoxygenase ALOX15 |
CHEMBL2903 |
NA |
296 |
68 |
0.9728 |
0.9883 |
| 794 |
Potassium voltage-gated channel subfamily A member 3 |
CHEMBL4633 |
NA |
152 |
20 |
0.9952 |
1 |
| 795 |
Potassium voltage-gated channel subfamily A member 5 |
CHEMBL4306 |
NA |
521 |
42 |
0.9956 |
0.9922 |
| 796 |
Pro-cathepsin H |
CHEMBL2225 |
NA |
28 |
12 |
0.9929 |
0.9896 |
| 797 |
Probable global transcription activator SNF2L2 |
CHEMBL2362979 |
NA |
56 |
25 |
0.948 |
0.9615 |
| 798 |
Procathepsin L |
CHEMBL3837 |
NA |
1344 |
675 |
0.9877 |
0.9954 |
| 799 |
Progesterone receptor |
CHEMBL208 |
NA |
1150 |
249 |
0.995 |
0.9889 |
| 800 |
Programmed cell death 1 ligand 1 |
CHEMBL3580522 |
NA |
105 |
75 |
0.968 |
0.9833 |
| 801 |
Proliferating cell nuclear antigen |
CHEMBL2346488 |
NA |
28 |
17 |
0.9841 |
0.984 |
| 802 |
Prolyl endopeptidase |
CHEMBL3202 |
NA |
291 |
93 |
0.9925 |
0.9993 |
| 803 |
Prolyl endopeptidase FAP |
CHEMBL4683 |
NA |
292 |
110 |
0.9994 |
0.9995 |
| 804 |
Proprotein convertase subtilisin/kexin type 6 |
CHEMBL2951 |
NA |
50 |
11 |
1 |
1 |
| 805 |
Proprotein convertase subtilisin/kexin type 9 |
CHEMBL2929 |
NA |
98 |
12 |
0.9793 |
0.928 |
| 806 |
Prostacyclin receptor |
CHEMBL1995 |
NA |
191 |
17 |
0.996 |
0.9959 |
| 807 |
Prostaglandin D2 receptor |
CHEMBL4427 |
NA |
327 |
37 |
0.9966 |
0.998 |
| 808 |
Prostaglandin D2 receptor 2 |
CHEMBL5071 |
NA |
1325 |
211 |
0.9991 |
0.9993 |
| 809 |
Prostaglandin E synthase |
CHEMBL5658 |
NA |
913 |
109 |
0.9864 |
0.9797 |
| 810 |
Prostaglandin E synthase 2 |
CHEMBL4411 |
NA |
36 |
18 |
0.9945 |
1 |
| 811 |
Prostaglandin E2 receptor EP1 subtype |
CHEMBL1811 |
NA |
592 |
102 |
0.999 |
0.9933 |
| 812 |
Prostaglandin E2 receptor EP2 subtype |
CHEMBL1881 |
NA |
266 |
42 |
0.9943 |
0.9976 |
| 813 |
Prostaglandin E2 receptor EP3 subtype |
CHEMBL3710 |
NA |
618 |
356 |
0.9955 |
0.9979 |
| 814 |
Prostaglandin E2 receptor EP4 subtype |
CHEMBL1836 |
NA |
524 |
101 |
0.9964 |
0.9977 |
| 815 |
Prostaglandin G/H synthase 1 |
CHEMBL221 |
NA |
719 |
256 |
0.9751 |
0.9689 |
| 816 |
Prostaglandin G/H synthase 2 |
CHEMBL230 |
NA |
2406 |
1054 |
0.974 |
0.9827 |
| 817 |
Prostasin |
CHEMBL5610 |
NA |
22 |
15 |
1 |
1 |
| 818 |
Prostate-specific antigen |
CHEMBL2099 |
NA |
32 |
15 |
0.9596 |
0.9998 |
| 819 |
Proteasome Macropain subunit |
CHEMBL3492 |
NA |
201 |
38 |
0.9809 |
0.9681 |
| 820 |
Proteasome Macropain subunit MB1 |
CHEMBL4662 |
NA |
975 |
498 |
0.9902 |
0.9973 |
| 821 |
Proteasome component C5 |
CHEMBL4208 |
NA |
166 |
65 |
0.9856 |
0.9775 |
| 822 |
Proteasome subunit beta type-10 |
CHEMBL3317334 |
NA |
79 |
15 |
0.9978 |
0.9984 |
| 823 |
Proteasome subunit beta type-8 |
CHEMBL5620 |
NA |
394 |
190 |
0.9945 |
0.9989 |
| 824 |
Proteasome subunit beta type-9 |
CHEMBL1944495 |
NA |
125 |
75 |
0.9993 |
0.9997 |
| 825 |
Protein AF-9 |
CHEMBL4295761 |
NA |
52 |
21 |
0.9898 |
0.9921 |
| 826 |
Protein ENL |
CHEMBL4295801 |
NA |
134 |
56 |
0.9803 |
0.9874 |
| 827 |
Protein Mdm4 |
CHEMBL1255126 |
NA |
202 |
33 |
0.9795 |
0.9672 |
| 828 |
Protein O-GlcNAcase |
CHEMBL5921 |
NA |
205 |
145 |
1 |
1 |
| 829 |
Protein arginine N-methyltransferase 1 |
CHEMBL5524 |
NA |
244 |
94 |
0.9761 |
0.9831 |
| 830 |
Protein arginine N-methyltransferase 3 |
CHEMBL5891 |
NA |
88 |
44 |
0.9884 |
0.9982 |
| 831 |
Protein arginine N-methyltransferase 5 |
CHEMBL1795116 |
NA |
362 |
151 |
0.9858 |
0.9912 |
| 832 |
Protein arginine N-methyltransferase 6 |
CHEMBL1275221 |
NA |
158 |
32 |
0.9908 |
0.9702 |
| 833 |
Protein arginine N-methyltransferase 8 |
CHEMBL3108648 |
NA |
61 |
15 |
0.9931 |
0.9354 |
| 834 |
Protein cereblon |
CHEMBL3763008 |
NA |
207 |
70 |
0.9955 |
0.9992 |
| 835 |
Protein delta homolog 1 |
CHEMBL5671 |
NA |
32 |
25 |
0.9365 |
0.9343 |
| 836 |
Protein kinase C alpha type |
CHEMBL299 |
NA |
407 |
218 |
0.9811 |
0.9817 |
| 837 |
Protein kinase C beta type |
CHEMBL3045 |
NA |
178 |
132 |
0.9474 |
0.9541 |
| 838 |
Protein kinase C delta type |
CHEMBL2996 |
NA |
293 |
218 |
0.9834 |
0.9894 |
| 839 |
Protein kinase C epsilon type |
CHEMBL3582 |
NA |
197 |
106 |
0.9665 |
0.9672 |
| 840 |
Protein kinase C eta type |
CHEMBL3616 |
NA |
77 |
69 |
0.9651 |
0.9609 |
| 841 |
Protein kinase C gamma type |
CHEMBL2938 |
NA |
82 |
53 |
0.9489 |
0.9348 |
| 842 |
Protein kinase C theta type |
CHEMBL3920 |
NA |
462 |
323 |
0.9823 |
0.9826 |
| 843 |
Protein kinase C zeta type |
CHEMBL3438 |
NA |
157 |
56 |
0.9928 |
0.9821 |
| 844 |
Protein mono-ADP-ribosyltransferase PARP10 |
CHEMBL2429708 |
NA |
150 |
12 |
0.9929 |
0.91 |
| 845 |
Protein mono-ADP-ribosyltransferase PARP14 |
CHEMBL2176777 |
NA |
131 |
11 |
0.9771 |
0.9847 |
| 846 |
Protein mono-ADP-ribosyltransferase PARP3 |
CHEMBL5083 |
NA |
46 |
13 |
0.9779 |
0.9584 |
| 847 |
Protein mono-ADP-ribosyltransferase TIPARP |
CHEMBL2380188 |
NA |
84 |
77 |
0.9912 |
0.9996 |
| 848 |
Protein polybromo-1 |
CHEMBL1795184 |
NA |
92 |
20 |
0.9651 |
0.9811 |
| 849 |
Protein tyrosine phosphatase type IVA 3 |
CHEMBL4162 |
NA |
51 |
22 |
0.9643 |
0.9819 |
| 850 |
Protein-S-isoprenylcysteine O-methyltransferase |
CHEMBL4699 |
NA |
109 |
52 |
0.9898 |
0.9965 |
| 851 |
Protein-arginine deiminase type-4 |
CHEMBL6111 |
NA |
96 |
17 |
0.9915 |
0.9999 |
| 852 |
Protein-glutamine gamma-glutamyltransferase |
CHEMBL2730 |
NA |
350 |
121 |
0.9867 |
0.9913 |
| 853 |
Protein-glutamine gamma-glutamyltransferase K |
CHEMBL2810 |
NA |
72 |
30 |
0.9824 |
0.9665 |
| 854 |
Protein-tyrosine kinase 2-beta |
CHEMBL5469 |
NA |
94 |
41 |
0.9513 |
0.8973 |
| 855 |
Protein-tyrosine kinase 6 |
CHEMBL4601 |
NA |
100 |
54 |
0.9409 |
0.9275 |
| 856 |
Proteinase-activated receptor 1 |
CHEMBL3974 |
NA |
462 |
98 |
0.9974 |
1 |
| 857 |
Prothrombin |
CHEMBL204 |
NA |
1703 |
914 |
0.9881 |
0.9909 |
| 858 |
Proto-oncogene tyrosine-protein kinase ROS |
CHEMBL5568 |
NA |
159 |
75 |
0.9714 |
0.9584 |
| 859 |
Proto-oncogene tyrosine-protein kinase Src |
CHEMBL267 |
NA |
1185 |
664 |
0.9612 |
0.9713 |
| 860 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
V804L |
592 |
22 |
0.9735 |
0.8944 |
| 861 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
M918T |
592 |
32 |
0.9735 |
0.8975 |
| 862 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
V804M |
592 |
67 |
0.9735 |
0.9753 |
| 863 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
NA |
592 |
284 |
0.9735 |
0.9648 |
| 864 |
Protoporphyrinogen oxidase |
CHEMBL1926488 |
NA |
89 |
27 |
0.9975 |
0.9991 |
| 865 |
Purine nucleoside phosphorylase |
CHEMBL4338 |
NA |
163 |
88 |
0.9927 |
0.9997 |
| 866 |
Puromycin-sensitive aminopeptidase |
CHEMBL2264 |
NA |
30 |
13 |
0.9917 |
0.9998 |
| 867 |
Pyruvate kinase PKLR |
CHEMBL1075126 |
NA |
35 |
10 |
0.9909 |
1 |
| 868 |
Pyruvate kinase PKM |
CHEMBL1075189 |
NA |
187 |
64 |
0.9693 |
0.9415 |
| 869 |
RAC-alpha serine/threonine-protein kinase |
CHEMBL4282 |
NA |
1012 |
388 |
0.9763 |
0.989 |
| 870 |
RAC-beta serine/threonine-protein kinase |
CHEMBL2431 |
NA |
286 |
130 |
0.9909 |
0.9911 |
| 871 |
RAC-gamma serine/threonine-protein kinase |
CHEMBL4816 |
NA |
217 |
77 |
0.9807 |
0.9685 |
| 872 |
RAF proto-oncogene serine/threonine-protein kinase |
CHEMBL1906 |
NA |
430 |
305 |
0.9796 |
0.9811 |
| 873 |
RNA demethylase ALKBH5 |
CHEMBL3621037 |
NA |
72 |
12 |
0.9581 |
0.9222 |
| 874 |
Rap guanine nucleotide exchange factor 3 |
CHEMBL2029197 |
NA |
73 |
38 |
0.9998 |
0.9965 |
| 875 |
Rap guanine nucleotide exchange factor 4 |
CHEMBL2029198 |
NA |
69 |
12 |
0.9771 |
1 |
| 876 |
RecQ-like DNA helicase BLM |
CHEMBL1293237 |
NA |
81 |
18 |
0.9866 |
0.9437 |
| 877 |
Receptor tyrosine-protein kinase erbB-2 |
CHEMBL1824 |
NA |
1086 |
325 |
0.981 |
0.9723 |
| 878 |
Receptor tyrosine-protein kinase erbB-3 |
CHEMBL5838 |
L858R |
52 |
10 |
0.9948 |
0.9952 |
| 879 |
Receptor tyrosine-protein kinase erbB-4 |
CHEMBL3009 |
NA |
196 |
69 |
0.981 |
0.9723 |
| 880 |
Receptor-interacting serine/threonine-protein kinase 1 |
CHEMBL5464 |
NA |
535 |
261 |
0.985 |
0.9754 |
| 881 |
Receptor-interacting serine/threonine-protein kinase 2 |
CHEMBL5014 |
NA |
335 |
172 |
0.9749 |
0.9744 |
| 882 |
Receptor-interacting serine/threonine-protein kinase 3 |
CHEMBL1795199 |
NA |
94 |
31 |
0.9505 |
0.9534 |
| 883 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
N841I |
2201 |
16 |
0.9752 |
0.9146 |
| 884 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
D835H |
2201 |
21 |
0.9752 |
0.8749 |
| 885 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
D835Y |
2201 |
176 |
0.9752 |
0.9631 |
| 886 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
UNDEFINED MUTATION |
2201 |
250 |
0.9752 |
0.9721 |
| 887 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
NA |
2201 |
989 |
0.9752 |
0.9673 |
| 888 |
Receptor-type tyrosine-protein phosphatase C |
CHEMBL3243 |
NA |
47 |
10 |
0.9821 |
0.8864 |
| 889 |
Receptor-type tyrosine-protein phosphatase F |
CHEMBL3521 |
NA |
40 |
18 |
0.9693 |
0.9217 |
| 890 |
Receptor-type tyrosine-protein phosphatase S |
CHEMBL2396508 |
NA |
27 |
11 |
0.9957 |
0.9824 |
| 891 |
Receptor-type tyrosine-protein phosphatase beta |
CHEMBL2706 |
NA |
64 |
34 |
0.9917 |
0.9775 |
| 892 |
Renin |
CHEMBL286 |
NA |
1287 |
1036 |
0.9984 |
0.9992 |
| 893 |
Replication protein A 70 kDa DNA-binding subunit |
CHEMBL1764940 |
NA |
74 |
38 |
0.9789 |
0.9834 |
| 894 |
Retinal dehydrogenase 2 |
CHEMBL3112384 |
NA |
75 |
41 |
0.9864 |
0.9853 |
| 895 |
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
CHEMBL3860 |
NA |
147 |
120 |
0.993 |
0.9991 |
| 896 |
Retinaldehyde dehydrogenase 3 |
CHEMBL3579 |
NA |
99 |
48 |
0.9916 |
0.9924 |
| 897 |
Retinoic acid receptor RXR-alpha |
CHEMBL2061 |
NA |
454 |
114 |
0.9923 |
0.9962 |
| 898 |
Retinoic acid receptor RXR-beta |
CHEMBL1870 |
NA |
216 |
26 |
0.9958 |
0.9999 |
| 899 |
Retinoic acid receptor RXR-gamma |
CHEMBL2004 |
NA |
183 |
31 |
0.9957 |
0.9999 |
| 900 |
Retinoic acid receptor alpha |
CHEMBL2055 |
NA |
95 |
41 |
0.9997 |
0.9998 |
| 901 |
Retinoic acid receptor beta |
CHEMBL2008 |
NA |
115 |
42 |
0.9997 |
0.9998 |
| 902 |
Retinoic acid receptor gamma |
CHEMBL2003 |
NA |
137 |
48 |
0.9997 |
0.9998 |
| 903 |
Retinol-binding protein 4 |
CHEMBL3100 |
NA |
160 |
108 |
0.9999 |
0.9999 |
| 904 |
Rho-associated protein kinase 1 |
CHEMBL3231 |
NA |
568 |
346 |
0.9838 |
0.9816 |
| 905 |
Rho-associated protein kinase 2 |
CHEMBL2973 |
NA |
907 |
545 |
0.9866 |
0.985 |
| 906 |
Ribosomal protein S6 kinase alpha-1 |
CHEMBL2553 |
NA |
69 |
42 |
0.898 |
0.8705 |
| 907 |
Ribosomal protein S6 kinase alpha-2 |
CHEMBL3906 |
NA |
72 |
42 |
0.8954 |
0.9176 |
| 908 |
Ribosomal protein S6 kinase alpha-3 |
CHEMBL2345 |
NA |
160 |
92 |
0.9593 |
0.9546 |
| 909 |
Ribosomal protein S6 kinase alpha-5 |
CHEMBL4237 |
NA |
87 |
47 |
0.9565 |
0.9756 |
| 910 |
Ribosomal protein S6 kinase alpha-6 |
CHEMBL4924 |
NA |
61 |
24 |
0.9517 |
0.8866 |
| 911 |
Ribosomal protein S6 kinase beta-1 |
CHEMBL4501 |
NA |
118 |
27 |
0.9577 |
0.8835 |
| 912 |
Ribosyldihydronicotinamide dehydrogenase [quinone] |
CHEMBL3959 |
NA |
231 |
67 |
0.9905 |
0.9849 |
| 913 |
S-adenosylmethionine decarboxylase proenzyme |
CHEMBL4181 |
NA |
19 |
11 |
0.9889 |
1 |
| 914 |
S-adenosylmethionine synthase isoform type-2 |
CHEMBL3313835 |
NA |
235 |
91 |
0.9986 |
0.9967 |
| 915 |
S-methyl-5'-thioadenosine phosphorylase |
CHEMBL4941 |
NA |
55 |
42 |
1 |
1 |
| 916 |
SRSF protein kinase 1 |
CHEMBL4375 |
NA |
45 |
36 |
0.943 |
0.9625 |
| 917 |
SRSF protein kinase 2 |
CHEMBL5668 |
NA |
30 |
24 |
0.9245 |
0.884 |
| 918 |
STE20-like serine/threonine-protein kinase |
CHEMBL4202 |
NA |
115 |
91 |
0.9607 |
0.9514 |
| 919 |
Secreted frizzled-related protein 1 |
CHEMBL5517 |
NA |
68 |
64 |
0.9882 |
0.988 |
| 920 |
Sentrin-specific protease 1 |
CHEMBL1909484 |
NA |
105 |
12 |
0.9848 |
0.9809 |
| 921 |
Sepiapterin reductase |
CHEMBL3988583 |
NA |
89 |
52 |
0.9628 |
0.9884 |
| 922 |
Serine protease 1 |
CHEMBL209 |
NA |
90 |
67 |
0.9989 |
0.9988 |
| 923 |
Serine protease HTRA1 |
CHEMBL4523419 |
NA |
25 |
13 |
0.9999 |
0.9989 |
| 924 |
Serine protease hepsin |
CHEMBL2079849 |
NA |
174 |
78 |
0.9977 |
0.9946 |
| 925 |
Serine-protein kinase ATM |
CHEMBL3797 |
NA |
427 |
248 |
0.9939 |
0.991 |
| 926 |
Serine/threonine-protein kinase 10 |
CHEMBL3981 |
NA |
109 |
70 |
0.968 |
0.9516 |
| 927 |
Serine/threonine-protein kinase 16 |
CHEMBL3938 |
NA |
42 |
17 |
0.9531 |
0.8864 |
| 928 |
Serine/threonine-protein kinase 17A |
CHEMBL4525 |
NA |
96 |
57 |
0.9652 |
0.9209 |
| 929 |
Serine/threonine-protein kinase 17B |
CHEMBL3980 |
NA |
127 |
40 |
0.9661 |
0.9511 |
| 930 |
Serine/threonine-protein kinase 25 |
CHEMBL5552 |
NA |
16 |
10 |
0.8855 |
0.8278 |
| 931 |
Serine/threonine-protein kinase 26 |
CHEMBL5941 |
NA |
63 |
11 |
0.9666 |
0.7184 |
| 932 |
Serine/threonine-protein kinase 3 |
CHEMBL4708 |
NA |
104 |
25 |
0.9668 |
0.9036 |
| 933 |
Serine/threonine-protein kinase 33 |
CHEMBL6005 |
NA |
36 |
21 |
0.8826 |
0.9077 |
| 934 |
Serine/threonine-protein kinase 4 |
CHEMBL4598 |
NA |
125 |
19 |
0.983 |
0.8773 |
| 935 |
Serine/threonine-protein kinase A-Raf |
CHEMBL1169596 |
NA |
31 |
27 |
0.9332 |
0.9254 |
| 936 |
Serine/threonine-protein kinase ATR |
CHEMBL5024 |
NA |
358 |
194 |
0.9963 |
0.9959 |
| 937 |
Serine/threonine-protein kinase B-raf |
CHEMBL5145 |
NA |
1950 |
336 |
0.9817 |
0.9779 |
| 938 |
Serine/threonine-protein kinase B-raf |
CHEMBL5145 |
V600E |
1950 |
426 |
0.9817 |
0.9814 |
| 939 |
Serine/threonine-protein kinase Chk1 |
CHEMBL4630 |
NA |
1059 |
655 |
0.9931 |
0.9938 |
| 940 |
Serine/threonine-protein kinase Chk2 |
CHEMBL2527 |
NA |
182 |
115 |
0.9683 |
0.9625 |
| 941 |
Serine/threonine-protein kinase D1 |
CHEMBL3863 |
NA |
83 |
50 |
0.9322 |
0.9193 |
| 942 |
Serine/threonine-protein kinase D2 |
CHEMBL4900 |
NA |
46 |
28 |
0.8967 |
0.8002 |
| 943 |
Serine/threonine-protein kinase D3 |
CHEMBL2595 |
NA |
32 |
18 |
0.8257 |
0.6742 |
| 944 |
Serine/threonine-protein kinase LATS2 |
CHEMBL5907 |
NA |
16 |
12 |
0.891 |
0.8165 |
| 945 |
Serine/threonine-protein kinase MARK2 |
CHEMBL3831 |
NA |
21 |
10 |
0.8537 |
0.9438 |
| 946 |
Serine/threonine-protein kinase N1 |
CHEMBL3384 |
NA |
72 |
36 |
0.9722 |
0.9553 |
| 947 |
Serine/threonine-protein kinase N2 |
CHEMBL3032 |
NA |
53 |
29 |
0.965 |
0.9816 |
| 948 |
Serine/threonine-protein kinase NLK |
CHEMBL5364 |
NA |
25 |
12 |
0.8815 |
0.8019 |
| 949 |
Serine/threonine-protein kinase Nek1 |
CHEMBL5855 |
NA |
35 |
12 |
0.9163 |
0.874 |
| 950 |
Serine/threonine-protein kinase Nek2 |
CHEMBL3835 |
NA |
123 |
27 |
0.9679 |
0.9259 |
| 951 |
Serine/threonine-protein kinase PAK 1 |
CHEMBL4600 |
NA |
293 |
130 |
0.9872 |
0.9907 |
| 952 |
Serine/threonine-protein kinase PAK 2 |
CHEMBL4487 |
NA |
30 |
16 |
0.9267 |
0.91 |
| 953 |
Serine/threonine-protein kinase PAK 3 |
CHEMBL2999 |
NA |
21 |
11 |
0.9128 |
0.8968 |
| 954 |
Serine/threonine-protein kinase PAK 4 |
CHEMBL4482 |
NA |
246 |
135 |
0.9875 |
0.9892 |
| 955 |
Serine/threonine-protein kinase PLK1 |
CHEMBL3024 |
NA |
792 |
237 |
0.9748 |
0.9805 |
| 956 |
Serine/threonine-protein kinase PLK2 |
CHEMBL5938 |
NA |
138 |
41 |
0.9729 |
0.9457 |
| 957 |
Serine/threonine-protein kinase PLK3 |
CHEMBL4897 |
NA |
104 |
12 |
0.937 |
0.7154 |
| 958 |
Serine/threonine-protein kinase PLK4 |
CHEMBL3788 |
NA |
346 |
254 |
0.9873 |
0.9885 |
| 959 |
Serine/threonine-protein kinase SIK1 |
CHEMBL6082 |
NA |
67 |
43 |
0.9623 |
0.9549 |
| 960 |
Serine/threonine-protein kinase SIK2 |
CHEMBL5699 |
NA |
134 |
76 |
0.9824 |
0.9761 |
| 961 |
Serine/threonine-protein kinase SIK3 |
CHEMBL6149 |
NA |
88 |
44 |
0.9836 |
0.9577 |
| 962 |
Serine/threonine-protein kinase Sgk1 |
CHEMBL2343 |
NA |
151 |
66 |
0.9734 |
0.9615 |
| 963 |
Serine/threonine-protein kinase TBK1 |
CHEMBL5408 |
NA |
146 |
78 |
0.9767 |
0.9635 |
| 964 |
Serine/threonine-protein kinase TNNI3K |
CHEMBL5260 |
NA |
219 |
60 |
0.9875 |
0.9636 |
| 965 |
Serine/threonine-protein kinase ULK1 |
CHEMBL6006 |
NA |
123 |
22 |
0.9759 |
0.7821 |
| 966 |
Serine/threonine-protein kinase ULK2 |
CHEMBL5435 |
NA |
26 |
14 |
0.9572 |
0.8942 |
| 967 |
Serine/threonine-protein kinase haspin |
CHEMBL1075163 |
NA |
98 |
29 |
0.9654 |
0.9815 |
| 968 |
Serine/threonine-protein kinase mTOR |
CHEMBL2842 |
NA |
1420 |
802 |
0.9883 |
0.9896 |
| 969 |
Serine/threonine-protein kinase pim-1 |
CHEMBL2147 |
NA |
1392 |
957 |
0.986 |
0.9918 |
| 970 |
Serine/threonine-protein kinase pim-2 |
CHEMBL4523 |
NA |
795 |
586 |
0.9929 |
0.9945 |
| 971 |
Serine/threonine-protein kinase pim-3 |
CHEMBL5407 |
NA |
474 |
362 |
0.9885 |
0.988 |
| 972 |
Serine/threonine-protein kinase tousled-like 2 |
CHEMBL5404 |
NA |
92 |
69 |
0.9785 |
0.9826 |
| 973 |
Serine/threonine-protein kinase/endoribonuclease IRE1 |
CHEMBL1163101 |
NA |
120 |
62 |
0.9846 |
0.9859 |
| 974 |
Serine/threonine-protein phosphatase 5 |
CHEMBL3425389 |
NA |
17 |
11 |
0.9703 |
0.9551 |
| 975 |
Sex hormone-binding globulin |
CHEMBL3305 |
NA |
94 |
76 |
0.9982 |
0.9993 |
| 976 |
Sigma intracellular receptor 2 |
CHEMBL4105907 |
NA |
462 |
175 |
0.9733 |
0.9719 |
| 977 |
Sigma non-opioid intracellular receptor 1 |
CHEMBL287 |
NA |
1044 |
173 |
0.9816 |
0.9728 |
| 978 |
Signal transducer and activator of transcription 3 |
CHEMBL4026 |
NA |
649 |
135 |
0.9757 |
0.9778 |
| 979 |
Signal transducer and activator of transcription 5B |
CHEMBL5817 |
NA |
44 |
20 |
0.9955 |
0.9716 |
| 980 |
Sodium channel protein type 1 subunit alpha |
CHEMBL1845 |
NA |
58 |
11 |
0.9623 |
0.9875 |
| 981 |
Sodium channel protein type 10 subunit alpha |
CHEMBL5451 |
NA |
204 |
31 |
0.9845 |
0.9932 |
| 982 |
Sodium channel protein type 2 subunit alpha |
CHEMBL4187 |
NA |
97 |
18 |
0.9423 |
0.9437 |
| 983 |
Sodium channel protein type 5 subunit alpha |
CHEMBL1980 |
NA |
562 |
69 |
0.9696 |
0.9537 |
| 984 |
Sodium channel protein type 9 subunit alpha |
CHEMBL4296 |
NA |
2436 |
858 |
0.9892 |
0.9949 |
| 985 |
Sodium- and chloride-dependent glycine transporter 1 |
CHEMBL2337 |
NA |
672 |
148 |
0.9964 |
0.9956 |
| 986 |
Sodium- and chloride-dependent glycine transporter 2 |
CHEMBL3060 |
NA |
154 |
14 |
0.9974 |
0.995 |
| 987 |
Sodium-dependent dopamine transporter |
CHEMBL238 |
NA |
1452 |
279 |
0.9868 |
0.9893 |
| 988 |
Sodium-dependent noradrenaline transporter |
CHEMBL222 |
NA |
1750 |
414 |
0.9915 |
0.9947 |
| 989 |
Sodium-dependent phosphate transport protein 2B |
CHEMBL4295685 |
NA |
67 |
15 |
0.9929 |
0.9898 |
| 990 |
Sodium-dependent serotonin transporter |
CHEMBL228 |
NA |
2911 |
722 |
0.9903 |
0.9938 |
| 991 |
Sodium/glucose cotransporter 2 |
CHEMBL3884 |
NA |
941 |
32 |
0.9992 |
0.9996 |
| 992 |
Sodium/hydrogen exchanger 1 |
CHEMBL2781 |
NA |
132 |
15 |
0.9979 |
0.9999 |
| 993 |
Solute carrier family 22 member 12 |
CHEMBL6120 |
NA |
339 |
18 |
0.9952 |
0.9495 |
| 994 |
Somatostatin receptor type 1 |
CHEMBL1917 |
NA |
137 |
40 |
0.9911 |
0.9906 |
| 995 |
Somatostatin receptor type 2 |
CHEMBL1804 |
NA |
280 |
57 |
0.992 |
0.9997 |
| 996 |
Somatostatin receptor type 3 |
CHEMBL2028 |
NA |
311 |
120 |
0.9978 |
0.9995 |
| 997 |
Somatostatin receptor type 4 |
CHEMBL1853 |
NA |
194 |
48 |
0.9932 |
0.9987 |
| 998 |
Somatostatin receptor type 5 |
CHEMBL1792 |
NA |
360 |
60 |
0.9963 |
0.986 |
| 999 |
Son of sevenless homolog 1 |
CHEMBL2079846 |
NA |
265 |
47 |
0.9964 |
0.999 |
| 1000 |
Sortilin |
CHEMBL3091 |
NA |
36 |
19 |
0.9503 |
0.9553 |
| 1001 |
Sphingomyelin phosphodiesterase |
CHEMBL2760 |
NA |
125 |
50 |
0.9688 |
0.9976 |
| 1002 |
Sphingomyelin phosphodiesterase 3 |
CHEMBL4523470 |
NA |
123 |
20 |
0.9961 |
1 |
| 1003 |
Sphingosine 1-phosphate receptor 1 |
CHEMBL4333 |
NA |
1526 |
112 |
0.995 |
0.9994 |
| 1004 |
Sphingosine 1-phosphate receptor 2 |
CHEMBL2955 |
NA |
238 |
49 |
0.9977 |
0.9833 |
| 1005 |
Sphingosine 1-phosphate receptor 3 |
CHEMBL3892 |
NA |
684 |
31 |
0.9956 |
0.9925 |
| 1006 |
Sphingosine 1-phosphate receptor 4 |
CHEMBL3230 |
NA |
287 |
35 |
0.9973 |
0.9928 |
| 1007 |
Sphingosine 1-phosphate receptor 5 |
CHEMBL2274 |
NA |
319 |
37 |
0.9964 |
0.9982 |
| 1008 |
Sphingosine kinase 1 |
CHEMBL4394 |
NA |
212 |
70 |
0.9804 |
0.9975 |
| 1009 |
Sphingosine kinase 2 |
CHEMBL3023 |
NA |
180 |
44 |
0.9961 |
0.999 |
| 1010 |
Sphingosine-1-phosphate lyase 1 |
CHEMBL3286061 |
NA |
35 |
11 |
0.9998 |
0.9358 |
| 1011 |
Stearoyl-CoA desaturase |
CHEMBL5555 |
NA |
503 |
52 |
0.9985 |
0.9849 |
| 1012 |
Steroid 17-alpha-hydroxylase/17,20 lyase |
CHEMBL3522 |
NA |
302 |
76 |
0.9994 |
0.9988 |
| 1013 |
Steroid hormone receptor ERR1 |
CHEMBL3429 |
NA |
128 |
74 |
0.9964 |
0.9996 |
| 1014 |
Steroid hormone receptor ERR2 |
CHEMBL3751 |
NA |
86 |
36 |
0.9993 |
0.9991 |
| 1015 |
Steroidogenic factor 1 |
CHEMBL4666 |
NA |
44 |
15 |
0.9719 |
1 |
| 1016 |
Sterol O-acyltransferase 1 |
CHEMBL2782 |
NA |
212 |
53 |
0.9878 |
0.9957 |
| 1017 |
Sterol O-acyltransferase 2 |
CHEMBL4465 |
NA |
128 |
50 |
0.9783 |
1 |
| 1018 |
Steryl-sulfatase |
CHEMBL3559 |
NA |
321 |
49 |
0.998 |
0.9939 |
| 1019 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
NA |
440 |
41 |
0.9921 |
0.9511 |
| 1020 |
Stromelysin-1 |
CHEMBL283 |
NA |
613 |
367 |
0.9806 |
0.9935 |
| 1021 |
Stromelysin-2 |
CHEMBL4270 |
NA |
97 |
68 |
0.989 |
0.9899 |
| 1022 |
Substance-K receptor |
CHEMBL2327 |
NA |
357 |
163 |
0.9744 |
0.9776 |
| 1023 |
Substance-P receptor |
CHEMBL249 |
NA |
844 |
83 |
0.9931 |
0.9837 |
| 1024 |
Sulfide:quinone oxidoreductase, mitochondrial |
CHEMBL4523512 |
NA |
27 |
23 |
0.9867 |
1 |
| 1025 |
Suppressor of tumorigenicity 14 protein |
CHEMBL3018 |
NA |
340 |
202 |
0.9932 |
0.9971 |
| 1026 |
TGF-beta receptor type-1 |
CHEMBL4439 |
T204D |
851 |
16 |
0.9902 |
1 |
| 1027 |
TGF-beta receptor type-1 |
CHEMBL4439 |
NA |
851 |
341 |
0.9902 |
0.9941 |
| 1028 |
TGF-beta receptor type-2 |
CHEMBL4267 |
NA |
131 |
58 |
0.9742 |
0.9786 |
| 1029 |
TRAF2 and NCK-interacting protein kinase |
CHEMBL4527 |
NA |
175 |
126 |
0.954 |
0.9479 |
| 1030 |
Tau-tubulin kinase 1 |
CHEMBL1926492 |
NA |
78 |
47 |
0.9998 |
1 |
| 1031 |
Tau-tubulin kinase 2 |
CHEMBL3337327 |
NA |
52 |
28 |
0.9997 |
0.9999 |
| 1032 |
Telomerase reverse transcriptase |
CHEMBL2916 |
NA |
445 |
55 |
0.9806 |
0.9749 |
| 1033 |
Telomeric repeat-binding factor 2 |
CHEMBL4296012 |
NA |
47 |
20 |
1 |
1 |
| 1034 |
Threonine--tRNA ligase 1, cytoplasmic |
CHEMBL3391 |
NA |
25 |
20 |
0.9984 |
0.9988 |
| 1035 |
Thromboxane A2 receptor |
CHEMBL2069 |
NA |
368 |
67 |
0.9901 |
0.9939 |
| 1036 |
Thromboxane-A synthase |
CHEMBL1835 |
NA |
63 |
23 |
0.9934 |
0.984 |
| 1037 |
Thymidine kinase 2, mitochondrial |
CHEMBL4580 |
NA |
33 |
12 |
1 |
0.9999 |
| 1038 |
Thymidine phosphorylase |
CHEMBL3106 |
NA |
170 |
21 |
0.9986 |
0.9998 |
| 1039 |
Thymidylate synthase |
CHEMBL1952 |
NA |
313 |
146 |
0.9907 |
0.984 |
| 1040 |
Thyroid hormone receptor alpha |
CHEMBL1860 |
NA |
270 |
100 |
0.9989 |
0.9993 |
| 1041 |
Thyroid hormone receptor beta |
CHEMBL1947 |
NA |
467 |
196 |
0.9958 |
0.9948 |
| 1042 |
Tissue alpha-L-fucosidase |
CHEMBL4176 |
NA |
21 |
17 |
0.9999 |
1 |
| 1043 |
Tissue factor |
CHEMBL4081 |
NA |
140 |
45 |
0.9907 |
0.9973 |
| 1044 |
Tissue-type plasminogen activator |
CHEMBL1873 |
NA |
121 |
59 |
0.9784 |
0.9919 |
| 1045 |
Toll-like receptor 7 |
CHEMBL5936 |
NA |
1136 |
28 |
0.9933 |
0.9858 |
| 1046 |
Toll-like receptor 8 |
CHEMBL5805 |
NA |
509 |
23 |
0.9936 |
0.9962 |
| 1047 |
Transcription activator BRG1 |
CHEMBL3085620 |
NA |
59 |
22 |
0.9769 |
0.9829 |
| 1048 |
Transcription factor p65 |
CHEMBL5533 |
NA |
79 |
12 |
0.9719 |
0.9074 |
| 1049 |
Transcription initiation factor TFIID subunit 1 |
CHEMBL3217390 |
NA |
147 |
48 |
0.9897 |
0.9775 |
| 1050 |
Transcription intermediary factor 1-alpha |
CHEMBL3108638 |
NA |
104 |
17 |
0.9891 |
0.9022 |
| 1051 |
Transcriptional enhancer factor TEF-1 |
CHEMBL3334416 |
NA |
31 |
12 |
0.9678 |
1 |
| 1052 |
Transcriptional enhancer factor TEF-3 |
CHEMBL4295828 |
NA |
63 |
13 |
0.9798 |
0.9612 |
| 1053 |
Transcriptional enhancer factor TEF-4 |
CHEMBL4523301 |
NA |
31 |
15 |
0.9493 |
0.9251 |
| 1054 |
Transcriptional enhancer factor TEF-5 |
CHEMBL4523435 |
NA |
21 |
12 |
0.9333 |
1 |
| 1055 |
Transient receptor potential cation channel subfamily A member 1 |
CHEMBL6007 |
NA |
521 |
68 |
0.9872 |
0.9922 |
| 1056 |
Transient receptor potential cation channel subfamily M member 8 |
CHEMBL1075319 |
NA |
430 |
43 |
0.9799 |
0.9604 |
| 1057 |
Transient receptor potential cation channel subfamily V member 1 |
CHEMBL4794 |
NA |
2160 |
158 |
0.9901 |
0.9801 |
| 1058 |
Transient receptor potential cation channel subfamily V member 4 |
CHEMBL3119 |
NA |
297 |
43 |
0.9901 |
0.9424 |
| 1059 |
Transitional endoplasmic reticulum ATPase |
CHEMBL1075145 |
NA |
326 |
159 |
0.9824 |
0.9967 |
| 1060 |
Translocator protein |
CHEMBL5742 |
NA |
135 |
49 |
0.9562 |
0.9257 |
| 1061 |
Transmembrane protease serine 11D |
CHEMBL1795138 |
NA |
42 |
41 |
1 |
1 |
| 1062 |
Transmembrane protease serine 2 |
CHEMBL1795140 |
NA |
39 |
19 |
0.9924 |
0.9984 |
| 1063 |
Transmembrane protease serine 6 |
CHEMBL1795139 |
NA |
90 |
29 |
0.9997 |
1 |
| 1064 |
Transthyretin |
CHEMBL3194 |
NA |
179 |
27 |
0.9879 |
0.9892 |
| 1065 |
Trifunctional purine biosynthetic protein adenosine-3 |
CHEMBL3972 |
NA |
69 |
19 |
0.9826 |
0.9618 |
| 1066 |
Tryptase beta-1 |
CHEMBL2617 |
NA |
162 |
119 |
0.9993 |
0.9995 |
| 1067 |
Tryptophan 2,3-dioxygenase |
CHEMBL2140 |
NA |
497 |
132 |
0.9897 |
0.9953 |
| 1068 |
Tryptophan 5-hydroxylase 1 |
CHEMBL5689 |
NA |
177 |
143 |
0.9954 |
0.9995 |
| 1069 |
Tryptophan 5-hydroxylase 2 |
CHEMBL5433 |
NA |
37 |
32 |
0.9993 |
0.9814 |
| 1070 |
Tumor necrosis factor |
CHEMBL1825 |
NA |
155 |
26 |
0.9741 |
0.9043 |
| 1071 |
Type-1 angiotensin II receptor |
CHEMBL227 |
NA |
391 |
212 |
0.9932 |
0.9991 |
| 1072 |
Type-2 angiotensin II receptor |
CHEMBL4607 |
NA |
137 |
31 |
0.9912 |
0.9693 |
| 1073 |
Tyrosinase |
CHEMBL1973 |
NA |
196 |
55 |
0.989 |
0.9895 |
| 1074 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
Y253F |
1000 |
17 |
0.9725 |
0.8 |
| 1075 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
Q252H |
1000 |
17 |
0.9725 |
0.8261 |
| 1076 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
H396P |
1000 |
18 |
0.9725 |
0.899 |
| 1077 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
M351T |
1000 |
20 |
0.9725 |
0.8885 |
| 1078 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
D382N |
1000 |
33 |
0.9725 |
0.9982 |
| 1079 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
T315I |
1000 |
55 |
0.9725 |
0.9266 |
| 1080 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
NA |
1000 |
488 |
0.9725 |
0.9719 |
| 1081 |
Tyrosine-protein kinase ABL2 |
CHEMBL4014 |
NA |
43 |
29 |
0.9114 |
0.865 |
| 1082 |
Tyrosine-protein kinase BTK |
CHEMBL5251 |
NA |
2027 |
978 |
0.99 |
0.9909 |
| 1083 |
Tyrosine-protein kinase Blk |
CHEMBL2250 |
NA |
163 |
73 |
0.9643 |
0.9296 |
| 1084 |
Tyrosine-protein kinase CSK |
CHEMBL2634 |
NA |
103 |
50 |
0.9471 |
0.9568 |
| 1085 |
Tyrosine-protein kinase FRK |
CHEMBL4223 |
NA |
60 |
39 |
0.9223 |
0.8738 |
| 1086 |
Tyrosine-protein kinase Fer |
CHEMBL3982 |
NA |
52 |
25 |
0.932 |
0.9013 |
| 1087 |
Tyrosine-protein kinase Fes/Fps |
CHEMBL5455 |
NA |
24 |
20 |
0.902 |
0.8589 |
| 1088 |
Tyrosine-protein kinase Fgr |
CHEMBL4454 |
NA |
66 |
43 |
0.8988 |
0.8644 |
| 1089 |
Tyrosine-protein kinase Fyn |
CHEMBL1841 |
NA |
135 |
60 |
0.9419 |
0.9084 |
| 1090 |
Tyrosine-protein kinase HCK |
CHEMBL3234 |
NA |
110 |
65 |
0.9482 |
0.9618 |
| 1091 |
Tyrosine-protein kinase ITK/TSK |
CHEMBL2959 |
NA |
410 |
277 |
0.9839 |
0.9808 |
| 1092 |
Tyrosine-protein kinase JAK1 |
CHEMBL2835 |
NA |
1557 |
950 |
0.9878 |
0.9849 |
| 1093 |
Tyrosine-protein kinase JAK2 |
CHEMBL2971 |
NA |
1936 |
1123 |
0.9826 |
0.9854 |
| 1094 |
Tyrosine-protein kinase JAK3 |
CHEMBL2148 |
NA |
1593 |
853 |
0.9828 |
0.9827 |
| 1095 |
Tyrosine-protein kinase Lck |
CHEMBL258 |
NA |
771 |
526 |
0.96 |
0.9699 |
| 1096 |
Tyrosine-protein kinase Lyn |
CHEMBL3905 |
NA |
161 |
107 |
0.9546 |
0.9262 |
| 1097 |
Tyrosine-protein kinase Mer |
CHEMBL5331 |
NA |
434 |
312 |
0.9806 |
0.9789 |
| 1098 |
Tyrosine-protein kinase SYK |
CHEMBL2599 |
NA |
716 |
474 |
0.9765 |
0.9909 |
| 1099 |
Tyrosine-protein kinase Srms |
CHEMBL5703 |
NA |
28 |
20 |
0.8124 |
0.8975 |
| 1100 |
Tyrosine-protein kinase TXK |
CHEMBL4367 |
NA |
99 |
71 |
0.9621 |
0.9758 |
| 1101 |
Tyrosine-protein kinase Tec |
CHEMBL4246 |
NA |
125 |
102 |
0.9755 |
0.9691 |
| 1102 |
Tyrosine-protein kinase Yes |
CHEMBL2073 |
NA |
131 |
88 |
0.9431 |
0.9196 |
| 1103 |
Tyrosine-protein kinase ZAP-70 |
CHEMBL2803 |
NA |
99 |
47 |
0.9563 |
0.9826 |
| 1104 |
Tyrosine-protein kinase receptor TYRO3 |
CHEMBL5314 |
NA |
340 |
236 |
0.9816 |
0.9782 |
| 1105 |
Tyrosine-protein kinase receptor Tie-1 |
CHEMBL5274 |
NA |
29 |
16 |
0.8916 |
0.8102 |
| 1106 |
Tyrosine-protein kinase receptor UFO |
CHEMBL4895 |
NA |
851 |
577 |
0.9815 |
0.985 |
| 1107 |
Tyrosine-protein phosphatase non-receptor type 1 |
CHEMBL335 |
NA |
2229 |
734 |
0.979 |
0.9892 |
| 1108 |
Tyrosine-protein phosphatase non-receptor type 11 |
CHEMBL3864 |
NA |
775 |
238 |
0.9797 |
0.9865 |
| 1109 |
Tyrosine-protein phosphatase non-receptor type 2 |
CHEMBL3807 |
NA |
488 |
129 |
0.9859 |
0.9911 |
| 1110 |
Tyrosine-protein phosphatase non-receptor type 22 |
CHEMBL2889 |
NA |
118 |
14 |
0.9872 |
0.9319 |
| 1111 |
Tyrosine-protein phosphatase non-receptor type 5 |
CHEMBL2007628 |
NA |
203 |
33 |
0.9865 |
0.9963 |
| 1112 |
Tyrosine-protein phosphatase non-receptor type 6 |
CHEMBL3166 |
NA |
173 |
49 |
0.9661 |
0.9789 |
| 1113 |
Tyrosyl-DNA phosphodiesterase 1 |
CHEMBL1075138 |
NA |
267 |
126 |
0.9868 |
0.9903 |
| 1114 |
Tyrosyl-DNA phosphodiesterase 2 |
CHEMBL2169736 |
NA |
231 |
94 |
0.9928 |
0.9827 |
| 1115 |
UDP-glucuronosyltransferase 2B7 |
CHEMBL4370 |
NA |
32 |
16 |
0.9996 |
0.9997 |
| 1116 |
Ubiquitin carboxyl-terminal hydrolase 21 |
CHEMBL2157852 |
NA |
16 |
11 |
0.9876 |
1 |
| 1117 |
Ubiquitin carboxyl-terminal hydrolase 30 |
CHEMBL4523357 |
NA |
27 |
25 |
1 |
1 |
| 1118 |
Ubiquitin carboxyl-terminal hydrolase 7 |
CHEMBL2157850 |
NA |
420 |
207 |
0.9925 |
0.9962 |
| 1119 |
Ubiquitin-like modifier-activating enzyme ATG7 |
CHEMBL2321621 |
NA |
31 |
27 |
1 |
1 |
| 1120 |
Urokinase-type plasminogen activator |
CHEMBL3286 |
NA |
395 |
157 |
0.9851 |
0.9992 |
| 1121 |
Urotensin-2 receptor |
CHEMBL3764 |
NA |
482 |
14 |
0.9968 |
0.9841 |
| 1122 |
V-type immunoglobulin domain-containing suppressor of T-cell activation |
CHEMBL4523457 |
NA |
58 |
22 |
0.9863 |
0.9932 |
| 1123 |
Vascular endothelial growth factor receptor 1 |
CHEMBL1868 |
NA |
412 |
300 |
0.9603 |
0.9679 |
| 1124 |
Vascular endothelial growth factor receptor 2 |
CHEMBL279 |
NA |
4227 |
2487 |
0.9653 |
0.97 |
| 1125 |
Vascular endothelial growth factor receptor 3 |
CHEMBL1955 |
NA |
218 |
158 |
0.9418 |
0.9264 |
| 1126 |
Vasopressin V1a receptor |
CHEMBL1889 |
NA |
783 |
157 |
0.9917 |
0.9869 |
| 1127 |
Vasopressin V2 receptor |
CHEMBL1790 |
NA |
511 |
83 |
0.9912 |
0.9835 |
| 1128 |
Very long chain fatty acid elongase 1 |
CHEMBL6001 |
NA |
66 |
13 |
0.9944 |
0.9803 |
| 1129 |
Vitamin D3 receptor |
CHEMBL1977 |
NA |
377 |
73 |
0.9934 |
0.9794 |
| 1130 |
Vitamin K-dependent protein C |
CHEMBL4444 |
NA |
87 |
30 |
0.9963 |
0.9911 |
| 1131 |
Voltage-dependent L-type calcium channel subunit alpha-1C |
CHEMBL1940 |
NA |
75 |
15 |
0.8779 |
0.7536 |
| 1132 |
Voltage-dependent N-type calcium channel subunit alpha-1B |
CHEMBL4478 |
NA |
410 |
10 |
0.9937 |
1 |
| 1133 |
Voltage-dependent calcium channel subunit alpha-2/delta-1 |
CHEMBL1919 |
NA |
169 |
29 |
0.9973 |
0.9855 |
| 1134 |
Voltage-gated inwardly rectifying potassium channel KCNH2 |
CHEMBL240 |
NA |
7553 |
1954 |
0.9255 |
0.9462 |
| 1135 |
WD repeat-containing protein 5 |
CHEMBL1075317 |
NA |
368 |
76 |
0.9915 |
0.9737 |
| 1136 |
Wee1-like protein kinase |
CHEMBL5491 |
NA |
480 |
372 |
0.9948 |
0.9978 |
| 1137 |
Xaa-Pro dipeptidase |
CHEMBL4185 |
NA |
45 |
14 |
0.9773 |
0.8829 |
| 1138 |
Xanthine dehydrogenase/oxidase |
CHEMBL1929 |
NA |
395 |
224 |
0.9852 |
0.9921 |
| 1139 |
YTH domain-containing protein 1 |
CHEMBL5169187 |
NA |
45 |
15 |
0.9926 |
0.9555 |
| 1140 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial |
CHEMBL4766 |
NA |
178 |
59 |
0.9453 |
0.958 |
| 1141 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial |
CHEMBL3861 |
NA |
130 |
69 |
0.9736 |
0.9964 |
| 1142 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial |
CHEMBL3893 |
NA |
40 |
19 |
0.9062 |
0.9668 |
| 1143 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial |
CHEMBL4141 |
NA |
84 |
40 |
0.9407 |
0.9966 |
| 1144 |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
CHEMBL4409 |
NA |
1126 |
584 |
0.9891 |
0.9958 |
| 1145 |
cAMP-dependent protein kinase catalytic subunit alpha |
CHEMBL4101 |
NA |
59 |
27 |
0.9169 |
0.8456 |
| 1146 |
cGMP-dependent 3',5'-cyclic phosphodiesterase |
CHEMBL2652 |
NA |
510 |
274 |
0.9856 |
0.994 |
| 1147 |
cGMP-dependent protein kinase 1 |
CHEMBL4273 |
NA |
82 |
30 |
0.9582 |
0.8759 |
| 1148 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A |
CHEMBL241 |
NA |
268 |
72 |
0.9743 |
0.9576 |
| 1149 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B |
CHEMBL290 |
NA |
133 |
39 |
0.9836 |
0.9843 |
| 1150 |
cGMP-specific 3',5'-cyclic phosphodiesterase |
CHEMBL1827 |
NA |
903 |
377 |
0.9821 |
0.9819 |
| 1151 |
dCTP pyrophosphatase 1 |
CHEMBL3769292 |
NA |
173 |
34 |
0.9896 |
0.9312 |
| 1152 |
eIF-2-alpha kinase GCN2 |
CHEMBL5358 |
NA |
93 |
57 |
0.9799 |
0.986 |
| 1153 |
m7GpppX diphosphatase |
CHEMBL1949488 |
NA |
35 |
29 |
0.9745 |
1 |
| 1154 |
von Hippel-Lindau disease tumor suppressor |
CHEMBL3108660 |
NA |
168 |
34 |
0.9988 |
0.9999 |