| 1 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
CHEMBL4521 |
NA |
55 |
27 |
0.9943 |
0.9987 |
| 2 |
1-acyl-sn-glycerol-3-phosphate acyltransferase beta |
CHEMBL4772 |
NA |
17 |
11 |
0.982 |
1 |
| 3 |
1-phosphatidylinositol 3-phosphate 5-kinase |
CHEMBL1938222 |
NA |
43 |
28 |
0.9921 |
0.9903 |
| 4 |
11-beta-hydroxysteroid dehydrogenase 1 |
CHEMBL4235 |
NA |
2216 |
1323 |
0.9907 |
0.9972 |
| 5 |
11-beta-hydroxysteroid dehydrogenase type 2 |
CHEMBL3746 |
NA |
145 |
32 |
0.9918 |
0.9991 |
| 6 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
CHEMBL1293255 |
NA |
221 |
111 |
0.9984 |
1 |
| 7 |
17-beta-hydroxysteroid dehydrogenase 13 |
CHEMBL5305042 |
NA |
38 |
24 |
1 |
1 |
| 8 |
17-beta-hydroxysteroid dehydrogenase 14 |
CHEMBL3712868 |
NA |
46 |
43 |
1 |
1 |
| 9 |
17-beta-hydroxysteroid dehydrogenase type 1 |
CHEMBL3181 |
NA |
501 |
379 |
0.9929 |
0.9976 |
| 10 |
17-beta-hydroxysteroid dehydrogenase type 2 |
CHEMBL2789 |
NA |
475 |
341 |
0.9942 |
0.9991 |
| 11 |
17-beta-hydroxysteroid dehydrogenase type 3 |
CHEMBL4234 |
NA |
175 |
112 |
0.9944 |
0.9998 |
| 12 |
2-acylglycerol O-acyltransferase 2 |
CHEMBL2439944 |
NA |
90 |
19 |
0.9998 |
1 |
| 13 |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase |
CHEMBL4739855 |
NA |
21 |
21 |
1 |
1 |
| 14 |
26S proteasome |
CHEMBL2364701 |
NA |
31 |
26 |
0.9998 |
0.9999 |
| 15 |
26S proteasome non-ATPase regulatory subunit 14 |
CHEMBL2007629 |
NA |
33 |
11 |
0.9936 |
1 |
| 16 |
3',5'-cyclic-AMP phosphodiesterase 4A |
CHEMBL254 |
NA |
292 |
34 |
0.9747 |
0.9795 |
| 17 |
3',5'-cyclic-AMP phosphodiesterase 4B |
CHEMBL275 |
S133D |
1291 |
17 |
0.9883 |
1 |
| 18 |
3',5'-cyclic-AMP phosphodiesterase 4B |
CHEMBL275 |
NA |
1291 |
187 |
0.9883 |
0.9827 |
| 19 |
3',5'-cyclic-AMP phosphodiesterase 4D |
CHEMBL288 |
NA |
867 |
168 |
0.9751 |
0.9805 |
| 20 |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
CHEMBL4931 |
NA |
64 |
42 |
0.9597 |
0.9649 |
| 21 |
3-hydroxy-3-methylglutaryl-coenzyme A reductase |
CHEMBL402 |
NA |
97 |
26 |
0.9949 |
0.9984 |
| 22 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
CHEMBL1787 |
NA |
68 |
38 |
0.9997 |
0.9997 |
| 23 |
3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
CHEMBL1856 |
NA |
160 |
54 |
0.9996 |
0.9994 |
| 24 |
3-phosphoinositide-dependent protein kinase 1 |
CHEMBL2534 |
NA |
200 |
44 |
0.9739 |
0.9999 |
| 25 |
4-hydroxyphenylpyruvate dioxygenase |
CHEMBL1861 |
NA |
111 |
63 |
0.9999 |
0.9999 |
| 26 |
5'-nucleotidase |
CHEMBL5957 |
NA |
360 |
214 |
0.9811 |
0.9985 |
| 27 |
5-hydroxytryptamine receptor 1A |
CHEMBL214 |
NA |
3638 |
2399 |
0.9815 |
0.9898 |
| 28 |
5-hydroxytryptamine receptor 1B |
CHEMBL1898 |
NA |
534 |
281 |
0.9755 |
0.9928 |
| 29 |
5-hydroxytryptamine receptor 1D |
CHEMBL1983 |
NA |
516 |
251 |
0.9804 |
0.9915 |
| 30 |
5-hydroxytryptamine receptor 1F |
CHEMBL1805 |
NA |
42 |
18 |
0.997 |
0.9999 |
| 31 |
5-hydroxytryptamine receptor 2A |
CHEMBL224 |
NA |
3335 |
1916 |
0.9789 |
0.9874 |
| 32 |
5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2 |
CHEMBL4630758 |
NA |
11 |
11 |
1 |
1 |
| 33 |
5-hydroxytryptamine receptor 2B |
CHEMBL1833 |
NA |
1140 |
640 |
0.9681 |
0.9821 |
| 34 |
5-hydroxytryptamine receptor 2C |
CHEMBL225 |
NA |
2273 |
1380 |
0.9788 |
0.9852 |
| 35 |
5-hydroxytryptamine receptor 3A |
CHEMBL1899 |
NA |
393 |
186 |
0.9769 |
0.9875 |
| 36 |
5-hydroxytryptamine receptor 4 |
CHEMBL1875 |
NA |
499 |
392 |
0.9943 |
0.999 |
| 37 |
5-hydroxytryptamine receptor 5A |
CHEMBL3426 |
NA |
186 |
35 |
0.9523 |
0.9704 |
| 38 |
5-hydroxytryptamine receptor 6 |
CHEMBL3371 |
NA |
3356 |
2443 |
0.9905 |
0.996 |
| 39 |
5-hydroxytryptamine receptor 7 |
CHEMBL3155 |
NA |
2238 |
1470 |
0.9845 |
0.9909 |
| 40 |
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 |
CHEMBL2331053 |
NA |
108 |
37 |
0.9962 |
0.9973 |
| 41 |
72 kDa type IV collagenase |
CHEMBL333 |
NA |
1515 |
51 |
0.9801 |
0.9686 |
| 42 |
A disintegrin and metalloproteinase with thrombospondin motifs 5 |
CHEMBL2285 |
NA |
273 |
35 |
0.9958 |
0.9954 |
| 43 |
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
CHEMBL4660 |
NA |
236 |
77 |
0.9996 |
1 |
| 44 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
G1269A |
1035 |
11 |
0.9875 |
0.8529 |
| 45 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
F1174L |
1035 |
13 |
0.9875 |
0.9136 |
| 46 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
C1156Y |
1035 |
22 |
0.9875 |
0.954 |
| 47 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
G1202R |
1035 |
36 |
0.9875 |
0.972 |
| 48 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
L1196M |
1035 |
156 |
0.9875 |
0.9934 |
| 49 |
ALK tyrosine kinase receptor |
CHEMBL4247 |
NA |
1035 |
280 |
0.9875 |
0.9955 |
| 50 |
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 |
CHEMBL2111345 |
NA |
74 |
57 |
0.9452 |
0.9373 |
| 51 |
AMPK alpha1/beta2/gamma1 |
CHEMBL3038453 |
NA |
16 |
14 |
0.9867 |
0.9999 |
| 52 |
AMPK alpha2/beta1/gamma1 |
CHEMBL3038455 |
NA |
76 |
42 |
0.9784 |
0.9673 |
| 53 |
AP2-associated protein kinase 1 |
CHEMBL3830 |
NA |
278 |
146 |
0.9746 |
0.9863 |
| 54 |
ATP-binding cassette sub-family C member 9 |
CHEMBL1971 |
NA |
51 |
27 |
0.9997 |
0.9998 |
| 55 |
ATP-dependent Clp protease proteolytic subunit, mitochondrial |
CHEMBL4523305 |
NA |
132 |
58 |
0.9878 |
0.9927 |
| 56 |
ATP-dependent RNA helicase DDX3X |
CHEMBL5553 |
NA |
108 |
24 |
0.9904 |
0.9999 |
| 57 |
ATP-dependent translocase ABCB1 |
CHEMBL4302 |
NA |
1505 |
658 |
0.9675 |
0.9823 |
| 58 |
ATP-sensitive inward rectifier potassium channel 1 |
CHEMBL1293292 |
NA |
252 |
218 |
0.9988 |
0.9985 |
| 59 |
ATPase family AAA domain-containing protein 2 |
CHEMBL2150837 |
NA |
193 |
68 |
0.9801 |
0.9791 |
| 60 |
ATR/ATRIP |
CHEMBL4106138 |
NA |
77 |
60 |
0.9957 |
0.9937 |
| 61 |
Acetyl-CoA carboxylase 1 |
CHEMBL3351 |
NA |
287 |
99 |
0.9934 |
0.9933 |
| 62 |
Acetyl-CoA carboxylase 2 |
CHEMBL4829 |
NA |
380 |
153 |
0.995 |
0.9977 |
| 63 |
Acetyl-coenzyme A synthetase, cytoplasmic |
CHEMBL4523467 |
NA |
23 |
23 |
1 |
1 |
| 64 |
Acetylcholine receptor; alpha1/beta1/delta/gamma |
CHEMBL1907588 |
NA |
49 |
26 |
0.9945 |
0.9893 |
| 65 |
Acetylcholinesterase |
CHEMBL220 |
NA |
3626 |
320 |
0.9697 |
0.9945 |
| 66 |
Acid ceramidase |
CHEMBL5463 |
NA |
151 |
99 |
0.9964 |
0.9963 |
| 67 |
Acid-sensing ion channel 3 |
CHEMBL5368 |
NA |
24 |
11 |
0.995 |
0.9974 |
| 68 |
Acidic mammalian chitinase |
CHEMBL1293197 |
NA |
119 |
77 |
0.977 |
1 |
| 69 |
Activated CDC42 kinase 1 |
CHEMBL4599 |
NA |
225 |
92 |
0.9772 |
0.9887 |
| 70 |
Activin receptor type-1 |
CHEMBL5903 |
R206H |
322 |
22 |
0.9869 |
0.9909 |
| 71 |
Activin receptor type-1 |
CHEMBL5903 |
NA |
322 |
100 |
0.9869 |
0.9958 |
| 72 |
Acyl-CoA (8-3)-desaturase |
CHEMBL5840 |
NA |
45 |
43 |
0.9806 |
0.9918 |
| 73 |
Adenosine kinase |
CHEMBL3589 |
NA |
195 |
11 |
0.9965 |
0.9651 |
| 74 |
Adenosine receptor A1 |
CHEMBL226 |
NA |
3887 |
2528 |
0.9852 |
0.9887 |
| 75 |
Adenosine receptor A2a |
CHEMBL251 |
NA |
4465 |
3010 |
0.9853 |
0.9924 |
| 76 |
Adenosine receptor A2b |
CHEMBL255 |
NA |
2147 |
1567 |
0.993 |
0.994 |
| 77 |
Adenosine receptor A3 |
CHEMBL256 |
NA |
3478 |
2577 |
0.9886 |
0.994 |
| 78 |
Adenosylhomocysteinase |
CHEMBL2664 |
NA |
121 |
21 |
0.9932 |
0.9999 |
| 79 |
Adenylate cyclase type 1 |
CHEMBL2899 |
NA |
101 |
52 |
0.9909 |
0.9991 |
| 80 |
Adenylate cyclase type 2 |
CHEMBL3760 |
NA |
40 |
15 |
0.968 |
1 |
| 81 |
Adenylate cyclase type 8 |
CHEMBL2960 |
NA |
63 |
31 |
0.9831 |
0.9691 |
| 82 |
Alanine--glyoxylate aminotransferase |
CHEMBL5169121 |
NA |
21 |
15 |
0.9997 |
0.9999 |
| 83 |
Aldehyde dehydrogenase 1A1 |
CHEMBL3577 |
NA |
288 |
50 |
0.9898 |
0.999 |
| 84 |
Aldo-keto reductase family 1 member A1 |
CHEMBL2246 |
NA |
68 |
23 |
0.999 |
0.9894 |
| 85 |
Aldo-keto reductase family 1 member B1 |
CHEMBL1900 |
NA |
399 |
113 |
0.9887 |
0.9974 |
| 86 |
Aldo-keto reductase family 1 member B10 |
CHEMBL5983 |
NA |
96 |
36 |
0.9956 |
0.9972 |
| 87 |
Aldo-keto reductase family 1 member C1 |
CHEMBL5905 |
NA |
103 |
16 |
0.959 |
0.9882 |
| 88 |
Aldo-keto reductase family 1 member C2 |
CHEMBL5847 |
NA |
222 |
47 |
0.9853 |
0.9907 |
| 89 |
Aldo-keto reductase family 1 member C3 |
CHEMBL4681 |
NA |
556 |
235 |
0.9745 |
0.99 |
| 90 |
Alkaline phosphatase, tissue-nonspecific isozyme |
CHEMBL5979 |
NA |
133 |
17 |
0.9954 |
0.9995 |
| 91 |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
CHEMBL2321630 |
NA |
124 |
75 |
0.9946 |
0.9999 |
| 92 |
Alpha-1A adrenergic receptor |
CHEMBL229 |
NA |
947 |
569 |
0.9784 |
0.9874 |
| 93 |
Alpha-1B adrenergic receptor |
CHEMBL232 |
NA |
617 |
377 |
0.981 |
0.988 |
| 94 |
Alpha-1D adrenergic receptor |
CHEMBL223 |
NA |
576 |
391 |
0.9873 |
0.9925 |
| 95 |
Alpha-2A adrenergic receptor |
CHEMBL1867 |
NA |
549 |
276 |
0.9729 |
0.9899 |
| 96 |
Alpha-2B adrenergic receptor |
CHEMBL1942 |
NA |
277 |
125 |
0.9611 |
0.9752 |
| 97 |
Alpha-2C adrenergic receptor |
CHEMBL1916 |
NA |
335 |
150 |
0.9714 |
0.9848 |
| 98 |
Alpha-ketoglutarate-dependent dioxygenase FTO |
CHEMBL2331065 |
NA |
167 |
39 |
0.9702 |
0.9927 |
| 99 |
Alpha-synuclein |
CHEMBL6152 |
NA |
208 |
43 |
0.9617 |
0.9653 |
| 100 |
Amine oxidase [copper-containing] 3 |
CHEMBL3437 |
NA |
185 |
114 |
0.9993 |
0.9994 |
| 101 |
Amine oxidase [flavin-containing] A |
CHEMBL1951 |
NA |
2033 |
396 |
0.9758 |
0.9929 |
| 102 |
Amine oxidase [flavin-containing] B |
CHEMBL2039 |
NA |
3526 |
740 |
0.9741 |
0.9939 |
| 103 |
Aminopeptidase N |
CHEMBL1907 |
NA |
265 |
70 |
0.9884 |
0.9968 |
| 104 |
Amyloid-beta precursor protein |
CHEMBL2487 |
NA |
1242 |
383 |
0.9724 |
0.9913 |
| 105 |
Androgen receptor |
CHEMBL1871 |
F877L |
1776 |
45 |
0.9893 |
0.9905 |
| 106 |
Androgen receptor |
CHEMBL1871 |
T878A |
1776 |
60 |
0.9893 |
0.996 |
| 107 |
Androgen receptor |
CHEMBL1871 |
NA |
1776 |
1016 |
0.9893 |
0.9924 |
| 108 |
Angiopoietin-1 receptor |
CHEMBL4128 |
NA |
466 |
84 |
0.972 |
0.9681 |
| 109 |
Angiotensin-converting enzyme |
CHEMBL1808 |
NA |
126 |
11 |
0.987 |
0.9925 |
| 110 |
Annexin A2/S100-A10 |
CHEMBL2111435 |
NA |
29 |
11 |
1 |
1 |
| 111 |
Anoctamin-1 |
CHEMBL2046267 |
NA |
113 |
31 |
0.9992 |
0.9932 |
| 112 |
Apelin receptor |
CHEMBL1628481 |
NA |
292 |
251 |
0.9973 |
0.9989 |
| 113 |
Apoptosis regulator BAX |
CHEMBL5318 |
NA |
37 |
12 |
0.9667 |
1 |
| 114 |
Apoptosis regulator Bcl-2 |
CHEMBL4860 |
NA |
816 |
92 |
0.9862 |
0.9852 |
| 115 |
Arachidonate 5-lipoxygenase-activating protein |
CHEMBL4550 |
NA |
369 |
258 |
0.9955 |
0.9997 |
| 116 |
Arginase-1 |
CHEMBL1075097 |
NA |
217 |
98 |
0.997 |
1 |
| 117 |
Arginase-2, mitochondrial |
CHEMBL1795148 |
NA |
67 |
22 |
1 |
1 |
| 118 |
Aromatase |
CHEMBL1978 |
NA |
2198 |
694 |
0.99 |
0.9962 |
| 119 |
Aryl hydrocarbon receptor |
CHEMBL3201 |
NA |
132 |
76 |
0.9757 |
0.9785 |
| 120 |
Aryl hydrocarbon receptor nuclear translocator/Endothelial PAS domain-containing protein 1 |
CHEMBL3885518 |
NA |
51 |
29 |
1 |
1 |
| 121 |
Aspartyl/asparaginyl beta-hydroxylase |
CHEMBL4680030 |
NA |
35 |
19 |
0.8847 |
0.9203 |
| 122 |
Atrial natriuretic peptide receptor 1 |
CHEMBL1988 |
NA |
50 |
29 |
0.9977 |
0.9941 |
| 123 |
Atypical chemokine receptor 3 |
CHEMBL2010631 |
NA |
313 |
148 |
0.9869 |
0.9901 |
| 124 |
Aurora kinase A |
CHEMBL4722 |
NA |
1103 |
296 |
0.9689 |
0.9813 |
| 125 |
Aurora kinase A/Targeting protein for Xklp2 |
CHEMBL3883304 |
NA |
18 |
10 |
0.9971 |
0.9992 |
| 126 |
Aurora kinase B |
CHEMBL2185 |
NA |
984 |
286 |
0.9735 |
0.9745 |
| 127 |
Aurora kinase B/Inner centromere protein |
CHEMBL3430907 |
NA |
99 |
48 |
0.9842 |
0.9538 |
| 128 |
Autotaxin |
CHEMBL3691 |
NA |
724 |
183 |
0.9827 |
0.989 |
| 129 |
B-cell lymphoma 6 protein |
CHEMBL4105786 |
C8Q,C67R,C84N |
235 |
31 |
0.9918 |
1 |
| 130 |
B-cell lymphoma 6 protein |
CHEMBL4105786 |
NA |
235 |
103 |
0.9918 |
1 |
| 131 |
B1 bradykinin receptor |
CHEMBL4308 |
NA |
483 |
310 |
0.9988 |
0.9979 |
| 132 |
B2 bradykinin receptor |
CHEMBL3157 |
NA |
144 |
111 |
0.9951 |
0.9999 |
| 133 |
BCL-6/NCOR2 |
CHEMBL4523673 |
NA |
32 |
19 |
0.9999 |
0.9999 |
| 134 |
BCL2/BCL2L11 |
CHEMBL5169264 |
NA |
31 |
28 |
0.9999 |
0.9999 |
| 135 |
BCL2A1/BID |
CHEMBL5169268 |
NA |
37 |
28 |
0.9509 |
0.9972 |
| 136 |
BDNF/NT-3 growth factors receptor |
CHEMBL4898 |
NA |
433 |
127 |
0.9696 |
0.9572 |
| 137 |
BMP-2-inducible protein kinase |
CHEMBL4522 |
NA |
58 |
20 |
0.9342 |
0.9684 |
| 138 |
Baculoviral IAP repeat-containing protein 2 |
CHEMBL5462 |
NA |
237 |
97 |
0.9995 |
0.9994 |
| 139 |
Baculoviral IAP repeat-containing protein 3 |
CHEMBL5335 |
NA |
90 |
27 |
0.9993 |
0.9993 |
| 140 |
Baculoviral IAP repeat-containing protein 7 |
CHEMBL1075127 |
NA |
13 |
11 |
0.9997 |
0.9996 |
| 141 |
Bcl-2-like protein 1 |
CHEMBL4625 |
NA |
526 |
58 |
0.9907 |
0.9983 |
| 142 |
Bcl-2-related protein A1 |
CHEMBL6044 |
NA |
93 |
15 |
0.9677 |
0.9795 |
| 143 |
Bcl-xL/BAK |
CHEMBL3137283 |
NA |
29 |
14 |
0.9852 |
0.992 |
| 144 |
Bcl-xL/Bcl-2-like protein 11 |
CHEMBL3883287 |
NA |
36 |
21 |
0.9963 |
0.9975 |
| 145 |
Bcl2-associated agonist of cell death |
CHEMBL3817 |
NA |
49 |
14 |
0.9687 |
1 |
| 146 |
Bcr/Abl fusion protein |
CHEMBL2096618 |
T315I |
431 |
61 |
0.9887 |
0.9812 |
| 147 |
Bcr/Abl fusion protein |
CHEMBL2096618 |
NA |
431 |
231 |
0.9887 |
0.9874 |
| 148 |
Beta-1 adrenergic receptor |
CHEMBL213 |
NA |
857 |
628 |
0.9897 |
0.9965 |
| 149 |
Beta-2 adrenergic receptor |
CHEMBL210 |
NA |
1087 |
760 |
0.9887 |
0.9968 |
| 150 |
Beta-3 adrenergic receptor |
CHEMBL246 |
NA |
826 |
707 |
0.9932 |
0.9978 |
| 151 |
Beta-adrenergic receptor kinase 1 |
CHEMBL4079 |
S670A |
224 |
16 |
0.9783 |
0.9996 |
| 152 |
Beta-adrenergic receptor kinase 1 |
CHEMBL4079 |
NA |
224 |
76 |
0.9783 |
0.9862 |
| 153 |
Beta-secretase 1 |
CHEMBL4822 |
NA |
2980 |
1389 |
0.9818 |
0.9987 |
| 154 |
Beta-secretase 2 |
CHEMBL2525 |
NA |
276 |
14 |
0.9949 |
0.9721 |
| 155 |
Bifunctional epoxide hydrolase 2 |
CHEMBL2409 |
NA |
2058 |
365 |
0.987 |
0.992 |
| 156 |
Bifunctional purine biosynthesis protein ATIC |
CHEMBL2518 |
NA |
64 |
21 |
0.9918 |
0.9998 |
| 157 |
Bile acid receptor |
CHEMBL2047 |
NA |
1378 |
630 |
0.987 |
0.9966 |
| 158 |
Bile salt export pump |
CHEMBL6020 |
NA |
30 |
13 |
0.6726 |
0.8413 |
| 159 |
Bombesin receptor subtype-3 |
CHEMBL4080 |
NA |
165 |
139 |
0.9985 |
0.9992 |
| 160 |
Bone morphogenetic protein 1 |
CHEMBL3898 |
NA |
99 |
94 |
0.9999 |
1 |
| 161 |
Bone morphogenetic protein receptor type-2 |
CHEMBL5467 |
NA |
43 |
19 |
0.9667 |
1 |
| 162 |
Branched-chain-amino-acid aminotransferase, cytosolic |
CHEMBL4679 |
NA |
70 |
30 |
0.9842 |
0.9929 |
| 163 |
Branched-chain-amino-acid aminotransferase, mitochondrial |
CHEMBL3616354 |
NA |
120 |
33 |
0.9937 |
1 |
| 164 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 |
CHEMBL5393 |
NA |
1017 |
562 |
0.9542 |
0.9891 |
| 165 |
Bromodomain adjacent to zinc finger domain protein 2B |
CHEMBL1741220 |
NA |
77 |
26 |
0.9723 |
0.9767 |
| 166 |
Bromodomain testis-specific protein |
CHEMBL1795185 |
NA |
148 |
34 |
0.9516 |
0.9198 |
| 167 |
Bromodomain-containing protein 1 |
CHEMBL2176774 |
NA |
82 |
42 |
0.9764 |
0.9946 |
| 168 |
Bromodomain-containing protein 2 |
CHEMBL1293289 |
NA |
276 |
58 |
0.9713 |
0.9244 |
| 169 |
Bromodomain-containing protein 3 |
CHEMBL1795186 |
NA |
262 |
50 |
0.9771 |
0.9161 |
| 170 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
Y97A |
3824 |
25 |
0.9819 |
0.9997 |
| 171 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
Y390A |
3824 |
115 |
0.9819 |
0.9997 |
| 172 |
Bromodomain-containing protein 4 |
CHEMBL1163125 |
NA |
3824 |
988 |
0.9819 |
0.9892 |
| 173 |
Bromodomain-containing protein 7 |
CHEMBL3085622 |
NA |
46 |
17 |
0.9565 |
0.9998 |
| 174 |
Bromodomain-containing protein 9 |
CHEMBL3108640 |
NA |
225 |
56 |
0.991 |
0.9831 |
| 175 |
Butyrophilin subfamily 3 member A1 |
CHEMBL4105758 |
NA |
51 |
36 |
1 |
0.9999 |
| 176 |
C-C chemokine receptor type 1 |
CHEMBL2413 |
NA |
409 |
298 |
0.9938 |
0.9988 |
| 177 |
C-C chemokine receptor type 10 |
CHEMBL2321628 |
NA |
33 |
26 |
1 |
1 |
| 178 |
C-C chemokine receptor type 2 |
CHEMBL4015 |
I40L |
1391 |
25 |
0.9953 |
1 |
| 179 |
C-C chemokine receptor type 2 |
CHEMBL4015 |
NA |
1391 |
840 |
0.9953 |
0.9956 |
| 180 |
C-C chemokine receptor type 3 |
CHEMBL3473 |
NA |
657 |
499 |
0.9936 |
0.9968 |
| 181 |
C-C chemokine receptor type 4 |
CHEMBL2414 |
NA |
347 |
251 |
0.9915 |
0.9989 |
| 182 |
C-C chemokine receptor type 5 |
CHEMBL274 |
NA |
1089 |
771 |
0.9891 |
0.9956 |
| 183 |
C-C chemokine receptor type 6 |
CHEMBL4423 |
NA |
75 |
58 |
0.9902 |
0.9923 |
| 184 |
C-C chemokine receptor type 8 |
CHEMBL4596 |
NA |
141 |
112 |
0.9974 |
0.9995 |
| 185 |
C-C chemokine receptor type 9 |
CHEMBL5815 |
NA |
120 |
70 |
0.9938 |
0.9921 |
| 186 |
C-C motif chemokine 2 |
CHEMBL1649052 |
NA |
47 |
37 |
0.9441 |
0.9612 |
| 187 |
C-X-C chemokine receptor type 1 |
CHEMBL4029 |
NA |
152 |
53 |
0.976 |
0.9915 |
| 188 |
C-X-C chemokine receptor type 2 |
CHEMBL2434 |
NA |
711 |
451 |
0.9973 |
0.999 |
| 189 |
C-X-C chemokine receptor type 3 |
CHEMBL4441 |
NA |
832 |
610 |
0.9957 |
0.998 |
| 190 |
C-X-C chemokine receptor type 4 |
CHEMBL2107 |
NA |
531 |
397 |
0.9865 |
0.9916 |
| 191 |
C-X-C chemokine receptor type 6 |
CHEMBL5994 |
NA |
49 |
28 |
0.9877 |
1 |
| 192 |
C3a anaphylatoxin chemotactic receptor |
CHEMBL4761 |
NA |
152 |
88 |
0.9999 |
0.9999 |
| 193 |
C5a anaphylatoxin chemotactic receptor 1 |
CHEMBL2373 |
NA |
265 |
185 |
0.9953 |
0.9941 |
| 194 |
CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase) |
CHEMBL2111377 |
NA |
230 |
190 |
0.9963 |
0.996 |
| 195 |
CDGSH iron-sulfur domain-containing protein 1 |
CHEMBL1795168 |
NA |
73 |
34 |
0.9293 |
0.9737 |
| 196 |
CDGSH iron-sulfur domain-containing protein 2 |
CHEMBL4523399 |
NA |
35 |
21 |
0.9997 |
1 |
| 197 |
CDK1/Cyclin A |
CHEMBL3038467 |
NA |
60 |
39 |
0.9764 |
0.9487 |
| 198 |
CDK12/Cyclin K |
CHEMBL4106169 |
NA |
150 |
137 |
0.9631 |
0.9631 |
| 199 |
CDK2/Cyclin A1 |
CHEMBL3038470 |
NA |
121 |
91 |
0.9819 |
0.9749 |
| 200 |
CDK2/Cyclin A2 |
CHEMBL3038469 |
NA |
835 |
536 |
0.9829 |
0.9836 |
| 201 |
CDK3/Cyclin E |
CHEMBL3038471 |
NA |
30 |
16 |
0.8822 |
0.8191 |
| 202 |
CDK4/Cyclin D3 |
CHEMBL3038472 |
NA |
143 |
132 |
0.9772 |
0.9799 |
| 203 |
CDK6/cyclin D1 |
CHEMBL2111455 |
NA |
161 |
138 |
0.9867 |
0.9881 |
| 204 |
CDK6/cyclin D3 |
CHEMBL2111448 |
NA |
252 |
219 |
0.9838 |
0.983 |
| 205 |
CDK7/Cyclin H/MNAT1 |
CHEMBL3038473 |
NA |
226 |
172 |
0.9666 |
0.9641 |
| 206 |
CDK8/Cyclin C |
CHEMBL3038474 |
NA |
500 |
465 |
0.9821 |
0.9845 |
| 207 |
CDK9/Cyclin K |
CHEMBL3038475 |
NA |
66 |
44 |
0.9765 |
0.9453 |
| 208 |
CDK9/cyclin T1 |
CHEMBL2111389 |
NA |
951 |
746 |
0.9832 |
0.9859 |
| 209 |
CREB-binding protein |
CHEMBL5747 |
NA |
491 |
102 |
0.9751 |
0.9848 |
| 210 |
CRY2/PER2 |
CHEMBL4296116 |
NA |
55 |
42 |
1 |
1 |
| 211 |
CX3C chemokine receptor 1 |
CHEMBL4843 |
NA |
48 |
43 |
0.981 |
1 |
| 212 |
Calcitonin gene-related peptide 1 |
CHEMBL5293 |
NA |
65 |
49 |
0.9898 |
0.985 |
| 213 |
Calcitonin gene-related peptide 2 |
CHEMBL3713541 |
NA |
24 |
23 |
1 |
1 |
| 214 |
Calcitonin gene-related peptide type 1 receptor |
CHEMBL3798 |
NA |
542 |
402 |
0.9982 |
0.9994 |
| 215 |
Calcitonin-gene-related peptide receptor, CALCRL/RAMP1 |
CHEMBL2107838 |
NA |
73 |
67 |
0.9896 |
0.9868 |
| 216 |
Calcium/calmodulin-dependent protein kinase kinase 2 |
CHEMBL5284 |
NA |
107 |
23 |
0.9584 |
0.9751 |
| 217 |
Calcium/calmodulin-dependent protein kinase type 1D |
CHEMBL5073 |
NA |
27 |
13 |
0.9027 |
1 |
| 218 |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
CHEMBL2801 |
NA |
57 |
34 |
0.9638 |
0.9992 |
| 219 |
Calpain 1 |
CHEMBL2111357 |
NA |
16 |
16 |
0.9999 |
0.9999 |
| 220 |
Calpain-1 catalytic subunit |
CHEMBL3891 |
NA |
246 |
66 |
0.993 |
0.9908 |
| 221 |
Cannabinoid receptor 1 |
CHEMBL218 |
NA |
3682 |
2340 |
0.986 |
0.9909 |
| 222 |
Cannabinoid receptor 2 |
CHEMBL253 |
Q63R |
4237 |
11 |
0.9897 |
0.9997 |
| 223 |
Cannabinoid receptor 2 |
CHEMBL253 |
NA |
4237 |
2667 |
0.9897 |
0.9918 |
| 224 |
Carbonic anhydrase 1 |
CHEMBL261 |
NA |
5499 |
328 |
0.9908 |
0.9996 |
| 225 |
Carbonic anhydrase 12 |
CHEMBL3242 |
NA |
4419 |
304 |
0.9905 |
0.9996 |
| 226 |
Carbonic anhydrase 13 |
CHEMBL3912 |
NA |
364 |
114 |
0.9914 |
0.9999 |
| 227 |
Carbonic anhydrase 14 |
CHEMBL3510 |
NA |
654 |
113 |
0.9902 |
0.9991 |
| 228 |
Carbonic anhydrase 2 |
CHEMBL205 |
N67I |
6038 |
10 |
0.9903 |
0.9977 |
| 229 |
Carbonic anhydrase 2 |
CHEMBL205 |
NA |
6038 |
380 |
0.9903 |
0.9993 |
| 230 |
Carbonic anhydrase 3 |
CHEMBL2885 |
NA |
180 |
51 |
0.9769 |
0.9998 |
| 231 |
Carbonic anhydrase 4 |
CHEMBL3729 |
NA |
1319 |
160 |
0.9918 |
0.9956 |
| 232 |
Carbonic anhydrase 5A, mitochondrial |
CHEMBL4789 |
NA |
570 |
99 |
0.9855 |
0.9997 |
| 233 |
Carbonic anhydrase 5B, mitochondrial |
CHEMBL3969 |
NA |
490 |
147 |
0.9908 |
0.9999 |
| 234 |
Carbonic anhydrase 6 |
CHEMBL3025 |
NA |
371 |
112 |
0.9861 |
0.9999 |
| 235 |
Carbonic anhydrase 7 |
CHEMBL2326 |
NA |
1414 |
132 |
0.9931 |
0.9991 |
| 236 |
Carbonic anhydrase 9 |
CHEMBL3594 |
NA |
5410 |
364 |
0.9903 |
0.9993 |
| 237 |
Carbonic anhydrase-related protein 11 |
CHEMBL2420 |
NA |
14 |
14 |
0.9994 |
0.9998 |
| 238 |
Carboxypeptidase B2 |
CHEMBL3419 |
NA |
185 |
28 |
0.9999 |
0.9995 |
| 239 |
Casein kinase I isoform delta |
CHEMBL2828 |
NA |
296 |
75 |
0.9779 |
0.9999 |
| 240 |
Casein kinase I isoform epsilon |
CHEMBL4937 |
NA |
203 |
65 |
0.9483 |
0.962 |
| 241 |
Casein kinase II alpha'/ beta |
CHEMBL3883328 |
NA |
83 |
58 |
0.9999 |
0.9999 |
| 242 |
Casein kinase II alpha/beta |
CHEMBL3038477 |
NA |
80 |
70 |
0.9826 |
0.9916 |
| 243 |
Casein kinase II subunit alpha |
CHEMBL3629 |
NA |
328 |
109 |
0.9723 |
0.995 |
| 244 |
Casein kinase II subunit alpha' |
CHEMBL4070 |
NA |
158 |
98 |
0.9724 |
0.998 |
| 245 |
Caspase-1 |
CHEMBL4801 |
NA |
364 |
70 |
0.9928 |
0.9882 |
| 246 |
Caspase-3 |
CHEMBL2334 |
NA |
713 |
164 |
0.9936 |
0.9973 |
| 247 |
Caspase-4 |
CHEMBL2226 |
NA |
21 |
13 |
0.9759 |
0.9233 |
| 248 |
Caspase-5 |
CHEMBL3131 |
NA |
22 |
16 |
0.9094 |
0.9377 |
| 249 |
Caspase-7 |
CHEMBL3468 |
NA |
317 |
43 |
0.9982 |
1 |
| 250 |
Caspase-8 |
CHEMBL3776 |
NA |
135 |
15 |
0.9895 |
0.9999 |
| 251 |
Catechol O-methyltransferase |
CHEMBL2023 |
NA |
131 |
73 |
0.9954 |
0.9992 |
| 252 |
Catenin beta-1 |
CHEMBL5866 |
NA |
98 |
27 |
0.9549 |
0.9648 |
| 253 |
Cathepsin B |
CHEMBL4072 |
NA |
915 |
93 |
0.9817 |
0.9995 |
| 254 |
Cathepsin D |
CHEMBL2581 |
NA |
763 |
143 |
0.9901 |
0.9865 |
| 255 |
Cathepsin K |
CHEMBL268 |
NA |
1239 |
72 |
0.9922 |
0.9994 |
| 256 |
Cathepsin L2 |
CHEMBL3272 |
NA |
91 |
21 |
0.9897 |
0.9997 |
| 257 |
Cathepsin S |
CHEMBL2954 |
NA |
1358 |
274 |
0.9969 |
0.9982 |
| 258 |
Cell division cycle 7-related protein kinase |
CHEMBL5443 |
NA |
189 |
45 |
0.9932 |
0.9812 |
| 259 |
Cellular tumor antigen p53 |
CHEMBL4096 |
NA |
45 |
11 |
0.9346 |
0.9226 |
| 260 |
Ceramide glucosyltransferase |
CHEMBL2063 |
NA |
152 |
67 |
0.9981 |
0.9951 |
| 261 |
Cereblon/Casein kinase I alpha |
CHEMBL4296102 |
NA |
10 |
10 |
1 |
1 |
| 262 |
Chemerin-like receptor 1 |
CHEMBL3540 |
NA |
108 |
74 |
0.9951 |
0.9996 |
| 263 |
Chitinase-3-like protein 1 |
CHEMBL5724768 |
NA |
26 |
20 |
0.9993 |
1 |
| 264 |
Chitotriosidase-1 |
CHEMBL3080 |
NA |
118 |
59 |
0.9953 |
0.9912 |
| 265 |
Chloride anion exchanger |
CHEMBL4523223 |
NA |
20 |
20 |
1 |
1 |
| 266 |
Cholecystokinin receptor type A |
CHEMBL1901 |
NA |
237 |
151 |
0.9901 |
0.995 |
| 267 |
Cholesterol 24-hydroxylase |
CHEMBL4523510 |
NA |
59 |
45 |
0.9994 |
0.9997 |
| 268 |
Cholesteryl ester transfer protein |
CHEMBL3572 |
NA |
614 |
51 |
0.9985 |
0.999 |
| 269 |
Cholinesterase |
CHEMBL1914 |
NA |
2654 |
179 |
0.9771 |
0.9944 |
| 270 |
Chromatin remodeling regulator CECR2 |
CHEMBL3108639 |
NA |
128 |
26 |
0.9885 |
0.9891 |
| 271 |
Chromobox protein homolog 7 |
CHEMBL1764946 |
NA |
79 |
39 |
0.9934 |
0.9995 |
| 272 |
Chromodomain Y-like protein |
CHEMBL3879827 |
NA |
58 |
22 |
0.9771 |
0.9923 |
| 273 |
Chromodomain Y-like protein 2 |
CHEMBL3879857 |
NA |
79 |
40 |
0.9994 |
0.9968 |
| 274 |
Coagulation factor VII/tissue factor |
CHEMBL2095194 |
NA |
263 |
206 |
0.9949 |
0.9984 |
| 275 |
Coagulation factor X |
CHEMBL244 |
NA |
2612 |
43 |
0.9942 |
0.9979 |
| 276 |
Coagulation factor XI |
CHEMBL2820 |
NA |
704 |
13 |
0.9952 |
0.9237 |
| 277 |
Cocaine esterase |
CHEMBL3180 |
NA |
229 |
38 |
0.9769 |
0.9969 |
| 278 |
Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET |
CHEMBL3430904 |
NA |
23 |
23 |
0.9166 |
0.9101 |
| 279 |
Collagenase 3 |
CHEMBL280 |
NA |
1309 |
110 |
0.986 |
0.9865 |
| 280 |
Complement factor D |
CHEMBL2176771 |
NA |
112 |
25 |
0.9889 |
1 |
| 281 |
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' |
CHEMBL3977 |
NA |
26 |
16 |
0.9414 |
0.9389 |
| 282 |
Corticotropin-releasing factor receptor 1 |
CHEMBL1800 |
NA |
880 |
684 |
0.9999 |
1 |
| 283 |
Cyclic AMP-dependent transcription factor ATF-4 |
CHEMBL6067624 |
NA |
39 |
38 |
1 |
1 |
| 284 |
Cyclic GMP-AMP synthase |
CHEMBL4105728 |
NA |
113 |
31 |
0.9759 |
0.9657 |
| 285 |
Cyclin-C/Cyclin-dependent kinase 19 |
CHEMBL3883323 |
NA |
102 |
98 |
0.9869 |
0.9886 |
| 286 |
Cyclin-G-associated kinase |
CHEMBL4355 |
NA |
236 |
114 |
0.9641 |
0.9979 |
| 287 |
Cyclin-dependent kinase 1 |
CHEMBL308 |
NA |
337 |
44 |
0.9653 |
0.9687 |
| 288 |
Cyclin-dependent kinase 1/cyclin B |
CHEMBL2094127 |
NA |
121 |
69 |
0.9724 |
0.9504 |
| 289 |
Cyclin-dependent kinase 1/cyclin B1 |
CHEMBL1907602 |
NA |
347 |
169 |
0.9647 |
0.9464 |
| 290 |
Cyclin-dependent kinase 11A |
CHEMBL5416 |
NA |
37 |
17 |
0.9629 |
1 |
| 291 |
Cyclin-dependent kinase 13/Cyclin-K |
CHEMBL4296067 |
NA |
36 |
31 |
0.9817 |
0.979 |
| 292 |
Cyclin-dependent kinase 14/Cyclin-Y |
CHEMBL4296115 |
NA |
60 |
57 |
0.9799 |
0.9899 |
| 293 |
Cyclin-dependent kinase 2 |
CHEMBL301 |
NA |
720 |
54 |
0.9509 |
0.9138 |
| 294 |
Cyclin-dependent kinase 2/cyclin A |
CHEMBL2094128 |
NA |
284 |
149 |
0.9758 |
0.9748 |
| 295 |
Cyclin-dependent kinase 2/cyclin E |
CHEMBL2094126 |
NA |
115 |
59 |
0.9809 |
0.9689 |
| 296 |
Cyclin-dependent kinase 2/cyclin E1 |
CHEMBL1907605 |
NA |
796 |
505 |
0.9856 |
0.9824 |
| 297 |
Cyclin-dependent kinase 4 |
CHEMBL331 |
NA |
217 |
20 |
0.9657 |
0.8928 |
| 298 |
Cyclin-dependent kinase 4/G1/S-specific cyclin-E1 |
CHEMBL3885554 |
NA |
29 |
29 |
0.9995 |
0.9996 |
| 299 |
Cyclin-dependent kinase 4/cyclin D1 |
CHEMBL1907601 |
NA |
478 |
324 |
0.9745 |
0.9757 |
| 300 |
Cyclin-dependent kinase 5/CDK5 activator 1 |
CHEMBL1907600 |
NA |
879 |
552 |
0.9798 |
0.9812 |
| 301 |
Cyclin-dependent kinase 6 |
CHEMBL2508 |
NA |
148 |
23 |
0.9741 |
1 |
| 302 |
Cyclin-dependent kinase 7 |
CHEMBL3055 |
NA |
182 |
11 |
0.9662 |
0.823 |
| 303 |
Cyclin-dependent kinase 7/ cyclin H |
CHEMBL2111288 |
NA |
145 |
99 |
0.9821 |
0.9737 |
| 304 |
Cyclin-dependent kinase 8 |
CHEMBL5719 |
NA |
385 |
169 |
0.9828 |
0.9925 |
| 305 |
Cyclin-dependent kinase 9 |
CHEMBL3116 |
NA |
374 |
91 |
0.9679 |
0.9827 |
| 306 |
Cyclin-dependent kinases regulatory subunit 1/S-phase kinase-associated protein 2 |
CHEMBL3885558 |
NA |
48 |
24 |
0.9893 |
0.9812 |
| 307 |
Cysteinyl leukotriene receptor 1 |
CHEMBL1798 |
NA |
200 |
174 |
0.9942 |
0.9977 |
| 308 |
Cysteinyl leukotriene receptor 2 |
CHEMBL4330 |
NA |
81 |
59 |
0.9842 |
0.9999 |
| 309 |
Cystic fibrosis transmembrane conductance regulator |
CHEMBL4051 |
G551D |
581 |
13 |
0.9839 |
0.9999 |
| 310 |
Cystic fibrosis transmembrane conductance regulator |
CHEMBL4051 |
N1303K |
581 |
15 |
0.9839 |
0.9569 |
| 311 |
Cystic fibrosis transmembrane conductance regulator |
CHEMBL4051 |
NA |
581 |
110 |
0.9839 |
0.9893 |
| 312 |
Cystic fibrosis transmembrane conductance regulator |
CHEMBL4051 |
F508del |
581 |
216 |
0.9839 |
0.9953 |
| 313 |
Cystine/glutamate transporter |
CHEMBL1075149 |
NA |
26 |
16 |
0.9987 |
1 |
| 314 |
Cytochrome P450 11B1, mitochondrial |
CHEMBL1908 |
NA |
589 |
433 |
0.9989 |
0.9988 |
| 315 |
Cytochrome P450 11B2, mitochondrial |
CHEMBL2722 |
NA |
774 |
727 |
0.9974 |
0.9974 |
| 316 |
Cytochrome P450 1A1 |
CHEMBL2231 |
NA |
70 |
24 |
0.9861 |
0.9981 |
| 317 |
Cytochrome P450 1A2 |
CHEMBL3356 |
NA |
49 |
22 |
0.9528 |
0.9815 |
| 318 |
Cytochrome P450 1B1 |
CHEMBL4878 |
NA |
360 |
118 |
0.9888 |
0.9948 |
| 319 |
Cytochrome P450 26A1 |
CHEMBL5141 |
NA |
132 |
77 |
0.9999 |
1 |
| 320 |
Cytochrome b-245 heavy chain |
CHEMBL1287627 |
NA |
80 |
31 |
0.9539 |
0.902 |
| 321 |
Cytoplasmic tyrosine-protein kinase BMX |
CHEMBL3834 |
NA |
205 |
81 |
0.9693 |
0.9846 |
| 322 |
Cytosolic phospholipase A2 |
CHEMBL3816 |
NA |
201 |
33 |
0.9956 |
0.9695 |
| 323 |
D(1A) dopamine receptor |
CHEMBL2056 |
NA |
848 |
460 |
0.9818 |
0.9912 |
| 324 |
D(1B) dopamine receptor |
CHEMBL1850 |
NA |
272 |
98 |
0.9878 |
0.9921 |
| 325 |
D(2) dopamine receptor |
CHEMBL217 |
NA |
4737 |
3089 |
0.985 |
0.9895 |
| 326 |
D(3) dopamine receptor |
CHEMBL234 |
V87F |
3262 |
12 |
0.9861 |
0.9999 |
| 327 |
D(3) dopamine receptor |
CHEMBL234 |
NA |
3262 |
2319 |
0.9861 |
0.9918 |
| 328 |
D(4) dopamine receptor |
CHEMBL219 |
NA |
1707 |
1126 |
0.9847 |
0.9893 |
| 329 |
D-3-phosphoglycerate dehydrogenase |
CHEMBL2311243 |
NA |
205 |
30 |
0.9905 |
0.9653 |
| 330 |
D-amino-acid oxidase |
CHEMBL5485 |
NA |
243 |
111 |
0.9993 |
0.9998 |
| 331 |
DCN1-like protein 1 |
CHEMBL4105838 |
NA |
229 |
62 |
0.9981 |
0.9752 |
| 332 |
DCN1-like protein 1/NEDD8-conjugating enzyme Ubc12 |
CHEMBL4523603 |
NA |
106 |
68 |
0.9944 |
0.9926 |
| 333 |
DDB1- and CUL4-associated factor 1 |
CHEMBL5465521 |
NA |
22 |
11 |
1 |
1 |
| 334 |
DNA (cytosine-5)-methyltransferase 1 |
CHEMBL1993 |
NA |
193 |
21 |
0.9749 |
0.9199 |
| 335 |
DNA (cytosine-5)-methyltransferase 3B |
CHEMBL6095 |
NA |
47 |
12 |
0.9336 |
0.9354 |
| 336 |
DNA excision repair protein ERCC-1/DNA repair endonuclease XPF |
CHEMBL3883316 |
NA |
80 |
42 |
0.9991 |
0.9997 |
| 337 |
DNA polymerase theta |
CHEMBL6025 |
NA |
116 |
41 |
0.9925 |
0.9999 |
| 338 |
DNA repair protein complementing XP-A cells |
CHEMBL4105801 |
NA |
23 |
12 |
1 |
1 |
| 339 |
DNA topoisomerase 1 |
CHEMBL1781 |
NA |
181 |
10 |
0.9751 |
1 |
| 340 |
DNA topoisomerase 2-alpha |
CHEMBL1806 |
NA |
340 |
15 |
0.969 |
0.934 |
| 341 |
DNA-dependent protein kinase catalytic subunit |
CHEMBL3142 |
NA |
602 |
82 |
0.9846 |
0.9894 |
| 342 |
DNA-directed RNA polymerase I subunit RPA1 |
CHEMBL3286067 |
NA |
60 |
28 |
0.9947 |
1 |
| 343 |
Delta(24)-sterol reductase |
CHEMBL2331059 |
NA |
13 |
11 |
0.9276 |
1 |
| 344 |
Delta-type opioid receptor |
CHEMBL236 |
NA |
2213 |
1434 |
0.9877 |
0.9925 |
| 345 |
Deoxycytidine kinase |
CHEMBL2447 |
NA |
99 |
87 |
0.9956 |
1 |
| 346 |
Deoxyhypusine synthase |
CHEMBL4415 |
NA |
59 |
14 |
0.9933 |
0.9996 |
| 347 |
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
CHEMBL5203 |
NA |
84 |
19 |
0.9884 |
1 |
| 348 |
Diacylglycerol O-acyltransferase 1 |
CHEMBL6009 |
NA |
580 |
347 |
0.9967 |
0.9997 |
| 349 |
Diacylglycerol O-acyltransferase 2 |
CHEMBL5853 |
NA |
67 |
54 |
0.9958 |
0.9939 |
| 350 |
Diacylglycerol lipase-alpha |
CHEMBL5545 |
NA |
134 |
94 |
0.9993 |
0.9999 |
| 351 |
Dihydrofolate reductase |
CHEMBL202 |
NA |
548 |
36 |
0.9934 |
0.9887 |
| 352 |
Dihydroorotate dehydrogenase (quinone), mitochondrial |
CHEMBL1966 |
NA |
817 |
183 |
0.991 |
0.9907 |
| 353 |
Dipeptidyl peptidase 1 |
CHEMBL2252 |
NA |
218 |
107 |
0.9955 |
0.9963 |
| 354 |
Dipeptidyl peptidase 2 |
CHEMBL3976 |
NA |
314 |
44 |
0.9959 |
0.9998 |
| 355 |
Dipeptidyl peptidase 4 |
CHEMBL284 |
NA |
2780 |
679 |
0.9892 |
0.9972 |
| 356 |
Dipeptidyl peptidase 8 |
CHEMBL4657 |
NA |
580 |
61 |
0.9976 |
0.9998 |
| 357 |
Dipeptidyl peptidase 9 |
CHEMBL4793 |
NA |
407 |
71 |
0.996 |
0.9998 |
| 358 |
Discoidin domain-containing receptor 2 |
CHEMBL5122 |
T654M |
219 |
19 |
0.9738 |
0.9421 |
| 359 |
Discoidin domain-containing receptor 2 |
CHEMBL5122 |
NA |
219 |
44 |
0.9738 |
0.9765 |
| 360 |
Disintegrin and metalloproteinase domain-containing protein 10 |
CHEMBL5028 |
NA |
71 |
25 |
0.9932 |
1 |
| 361 |
Disintegrin and metalloproteinase domain-containing protein 17 |
CHEMBL3706 |
NA |
828 |
274 |
0.9976 |
0.9999 |
| 362 |
Disintegrin and metalloproteinase domain-containing protein 8 |
CHEMBL5665 |
NA |
17 |
14 |
1 |
1 |
| 363 |
Disks large homolog 4 |
CHEMBL5666 |
NA |
24 |
12 |
1 |
1 |
| 364 |
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
CHEMBL2717 |
NA |
95 |
29 |
0.9723 |
0.9835 |
| 365 |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
CHEMBL4619 |
NA |
71 |
12 |
0.9831 |
0.8627 |
| 366 |
Dual specificity mitogen-activated protein kinase kinase 1 |
CHEMBL3587 |
S218E,S222E |
417 |
23 |
0.9726 |
1 |
| 367 |
Dual specificity mitogen-activated protein kinase kinase 1 |
CHEMBL3587 |
NA |
417 |
90 |
0.9726 |
0.9796 |
| 368 |
Dual specificity mitogen-activated protein kinase kinase 4 |
CHEMBL2897 |
NA |
56 |
19 |
0.948 |
1 |
| 369 |
Dual specificity mitogen-activated protein kinase kinase 7 |
CHEMBL3530 |
NA |
67 |
11 |
0.9796 |
0.9442 |
| 370 |
Dual specificity protein kinase CLK1 |
CHEMBL4224 |
NA |
653 |
289 |
0.9708 |
0.9757 |
| 371 |
Dual specificity protein kinase CLK2 |
CHEMBL4225 |
NA |
419 |
51 |
0.9528 |
0.8864 |
| 372 |
Dual specificity protein kinase CLK3 |
CHEMBL4226 |
NA |
225 |
99 |
0.9649 |
0.9693 |
| 373 |
Dual specificity protein kinase CLK4 |
CHEMBL4203 |
NA |
420 |
66 |
0.964 |
0.9224 |
| 374 |
Dual specificity protein kinase TTK |
CHEMBL3983 |
NA |
512 |
233 |
0.9909 |
0.998 |
| 375 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A |
CHEMBL2292 |
NA |
1361 |
417 |
0.9808 |
0.981 |
| 376 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
CHEMBL5543 |
NA |
602 |
143 |
0.9768 |
0.9523 |
| 377 |
Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
CHEMBL4376 |
NA |
473 |
134 |
0.9805 |
0.9834 |
| 378 |
Dual specificity tyrosine-phosphorylation-regulated kinase 3 |
CHEMBL4575 |
NA |
287 |
64 |
0.969 |
0.9637 |
| 379 |
E3 SUMO-protein ligase CBX4 |
CHEMBL3232685 |
NA |
24 |
14 |
1 |
1 |
| 380 |
E3 ubiquitin-protein ligase CBL-B |
CHEMBL4879459 |
NA |
127 |
43 |
0.9986 |
0.9748 |
| 381 |
E3 ubiquitin-protein ligase Mdm2 |
CHEMBL5023 |
NA |
968 |
295 |
0.988 |
0.9981 |
| 382 |
E3 ubiquitin-protein ligase XIAP |
CHEMBL4198 |
NA |
465 |
159 |
0.9983 |
0.9999 |
| 383 |
E3 ubiquitin-protein ligase XIAP/Receptor-interacting serine/threonine-protein kinase 2 |
CHEMBL4888447 |
NA |
20 |
20 |
1 |
1 |
| 384 |
EML4-ALK |
CHEMBL3883330 |
L1152R |
39 |
17 |
0.986 |
0.9672 |
| 385 |
EML4-ALK |
CHEMBL3883330 |
S1206Y |
39 |
19 |
0.986 |
0.991 |
| 386 |
EML4-ALK |
CHEMBL3883330 |
C1156Y |
39 |
20 |
0.986 |
0.9911 |
| 387 |
EML4-ALK |
CHEMBL3883330 |
F1174L |
39 |
20 |
0.986 |
0.9911 |
| 388 |
EML4-ALK |
CHEMBL3883330 |
G1269A |
39 |
20 |
0.986 |
0.9911 |
| 389 |
EML4-ALK |
CHEMBL3883330 |
L1196M |
39 |
22 |
0.986 |
0.985 |
| 390 |
EML4-ALK |
CHEMBL3883330 |
G1202R |
39 |
23 |
0.986 |
0.9824 |
| 391 |
EML4-ALK |
CHEMBL3883330 |
NA |
39 |
33 |
0.986 |
0.9837 |
| 392 |
EZH1/SUZ12/EED/AEBP2/RBBP4 complex |
CHEMBL3137287 |
NA |
25 |
24 |
1 |
1 |
| 393 |
Early activation antigen CD69 |
CHEMBL3308911 |
NA |
34 |
20 |
0.9718 |
0.9435 |
| 394 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
CHEMBL5925 |
NA |
275 |
81 |
0.9891 |
0.9856 |
| 395 |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
CHEMBL5580 |
NA |
115 |
27 |
0.9674 |
0.9524 |
| 396 |
Egl nine homolog 1 |
CHEMBL5697 |
NA |
454 |
83 |
0.9971 |
0.9956 |
| 397 |
Endoplasmic reticulum aminopeptidase 1 |
CHEMBL5939 |
NA |
145 |
42 |
0.9844 |
0.9726 |
| 398 |
Endoplasmic reticulum aminopeptidase 2 |
CHEMBL5043 |
NA |
154 |
62 |
0.9924 |
0.9994 |
| 399 |
Endothelial PAS domain-containing protein 1 |
CHEMBL1744522 |
NA |
154 |
51 |
0.9892 |
0.9943 |
| 400 |
Endothelial lipase |
CHEMBL5080 |
NA |
128 |
74 |
0.9922 |
0.9772 |
| 401 |
Endothelin receptor type B |
CHEMBL1785 |
NA |
151 |
77 |
0.9974 |
0.9993 |
| 402 |
Endothelin-1 receptor |
CHEMBL252 |
NA |
270 |
196 |
0.9959 |
0.9948 |
| 403 |
Ephrin type-A receptor 2 |
CHEMBL2068 |
NA |
97 |
17 |
0.9476 |
0.9256 |
| 404 |
Ephrin type-A receptor 4 |
CHEMBL3988 |
NA |
62 |
34 |
0.9251 |
0.9532 |
| 405 |
Ephrin type-B receptor 4 |
CHEMBL5147 |
NA |
180 |
63 |
0.9627 |
0.9917 |
| 406 |
Epidermal growth factor receptor |
CHEMBL203 |
T790M,L858M |
5377 |
12 |
0.9722 |
1 |
| 407 |
Epidermal growth factor receptor |
CHEMBL203 |
C797S,L858R |
5377 |
24 |
0.9722 |
1 |
| 408 |
Epidermal growth factor receptor |
CHEMBL203 |
L861Q |
5377 |
40 |
0.9722 |
0.9687 |
| 409 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R,T790M,C797S |
5377 |
111 |
0.9722 |
0.987 |
| 410 |
Epidermal growth factor receptor |
CHEMBL203 |
T790M |
5377 |
122 |
0.9722 |
0.9767 |
| 411 |
Epidermal growth factor receptor |
CHEMBL203 |
UNDEFINED MUTATION |
5377 |
186 |
0.9722 |
0.9942 |
| 412 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R |
5377 |
420 |
0.9722 |
0.9893 |
| 413 |
Epidermal growth factor receptor |
CHEMBL203 |
L858R,T790M |
5377 |
889 |
0.9722 |
0.9938 |
| 414 |
Epidermal growth factor receptor |
CHEMBL203 |
NA |
5377 |
1429 |
0.9722 |
0.987 |
| 415 |
Epithelial discoidin domain-containing receptor 1 |
CHEMBL5319 |
NA |
258 |
93 |
0.9578 |
0.9725 |
| 416 |
Equilibrative nucleoside transporter 1 |
CHEMBL1997 |
NA |
148 |
110 |
0.9977 |
0.9938 |
| 417 |
Estrogen receptor |
CHEMBL206 |
S463P |
2436 |
11 |
0.9882 |
0.9997 |
| 418 |
Estrogen receptor |
CHEMBL206 |
D538G |
2436 |
21 |
0.9882 |
0.9995 |
| 419 |
Estrogen receptor |
CHEMBL206 |
Y537S |
2436 |
22 |
0.9882 |
0.9977 |
| 420 |
Estrogen receptor |
CHEMBL206 |
NA |
2436 |
1226 |
0.9882 |
0.996 |
| 421 |
Estrogen receptor beta |
CHEMBL242 |
NA |
1347 |
523 |
0.9915 |
0.9958 |
| 422 |
Estrogen-related receptor gamma |
CHEMBL4245 |
NA |
206 |
51 |
0.9979 |
0.9999 |
| 423 |
Eukaryotic initiation factor 4A-I |
CHEMBL2052028 |
NA |
72 |
31 |
0.9805 |
0.9943 |
| 424 |
Eukaryotic initiation factor 4A-III |
CHEMBL4105832 |
NA |
48 |
22 |
0.9553 |
0.9886 |
| 425 |
Eukaryotic translation initiation factor 2-alpha kinase 3 |
CHEMBL6030 |
NA |
84 |
64 |
0.9993 |
0.9998 |
| 426 |
Eukaryotic translation initiation factor 4E |
CHEMBL4848 |
NA |
87 |
31 |
0.9715 |
0.9835 |
| 427 |
Excitatory amino acid transporter 1 |
CHEMBL3085 |
NA |
113 |
64 |
0.9993 |
0.9999 |
| 428 |
Excitatory amino acid transporter 2 |
CHEMBL4973 |
NA |
110 |
42 |
0.995 |
0.9995 |
| 429 |
Excitatory amino acid transporter 3 |
CHEMBL2721 |
NA |
76 |
37 |
0.9993 |
0.9999 |
| 430 |
Exportin-1 |
CHEMBL5661 |
NA |
65 |
40 |
0.9685 |
0.9991 |
| 431 |
Extracellular calcium-sensing receptor |
CHEMBL1878 |
NA |
318 |
216 |
0.9998 |
0.9998 |
| 432 |
Farnesyl pyrophosphate synthase |
CHEMBL1782 |
NA |
199 |
67 |
0.9943 |
0.9998 |
| 433 |
Fatty acid synthase |
CHEMBL4158 |
NA |
177 |
18 |
0.9903 |
0.9636 |
| 434 |
Fatty acid-binding protein 5 |
CHEMBL3674 |
NA |
132 |
20 |
0.9935 |
0.9999 |
| 435 |
Fatty acid-binding protein, adipocyte |
CHEMBL2083 |
NA |
269 |
46 |
0.9918 |
0.998 |
| 436 |
Fatty acid-binding protein, brain |
CHEMBL3826863 |
NA |
43 |
11 |
0.9968 |
1 |
| 437 |
Fatty-acid amide hydrolase 1 |
CHEMBL2243 |
NA |
1169 |
397 |
0.9911 |
0.9957 |
| 438 |
Fibroblast growth factor receptor 1 |
CHEMBL3650 |
NA |
1094 |
189 |
0.9825 |
0.9792 |
| 439 |
Fibroblast growth factor receptor 2 |
CHEMBL4142 |
NA |
381 |
125 |
0.9828 |
0.9923 |
| 440 |
Fibroblast growth factor receptor 3 |
CHEMBL2742 |
K650E |
374 |
14 |
0.9844 |
1 |
| 441 |
Fibroblast growth factor receptor 3 |
CHEMBL2742 |
NA |
374 |
162 |
0.9844 |
0.9936 |
| 442 |
Fibroblast growth factor receptor 4 |
CHEMBL3973 |
NA |
662 |
265 |
0.9908 |
0.997 |
| 443 |
Focal adhesion kinase 1 |
CHEMBL2695 |
NA |
801 |
188 |
0.9789 |
0.9823 |
| 444 |
Folate receptor alpha |
CHEMBL2121 |
NA |
58 |
58 |
0.9999 |
0.9999 |
| 445 |
Folate receptor beta |
CHEMBL5064 |
NA |
38 |
38 |
0.9999 |
0.9999 |
| 446 |
Follicle-stimulating hormone receptor |
CHEMBL2024 |
NA |
41 |
19 |
0.9788 |
0.9571 |
| 447 |
Free fatty acid receptor 1 |
CHEMBL4422 |
NA |
1577 |
1036 |
0.9979 |
0.9983 |
| 448 |
Free fatty acid receptor 2 |
CHEMBL5493 |
NA |
203 |
99 |
0.9979 |
0.9998 |
| 449 |
Free fatty acid receptor 3 |
CHEMBL5201 |
NA |
65 |
25 |
0.9998 |
1 |
| 450 |
Free fatty acid receptor 4 |
CHEMBL5339 |
NA |
432 |
247 |
0.999 |
0.999 |
| 451 |
Fructose-1,6-bisphosphatase 1 |
CHEMBL3975 |
NA |
570 |
321 |
0.9942 |
0.9971 |
| 452 |
Furin |
CHEMBL2611 |
NA |
236 |
67 |
0.9943 |
1 |
| 453 |
G protein-coupled receptor 88 |
CHEMBL3399910 |
NA |
274 |
214 |
1 |
1 |
| 454 |
G protein-coupled receptor kinase 5 |
CHEMBL5678 |
NA |
164 |
32 |
0.9922 |
0.9988 |
| 455 |
G-protein coupled bile acid receptor 1 |
CHEMBL5409 |
NA |
659 |
459 |
0.9924 |
0.9943 |
| 456 |
G-protein coupled receptor 183 |
CHEMBL3259470 |
NA |
93 |
90 |
0.9891 |
0.99 |
| 457 |
G-protein coupled receptor 35 |
CHEMBL1293267 |
NA |
263 |
123 |
0.9945 |
0.9954 |
| 458 |
G-protein coupled receptor 39 |
CHEMBL3091266 |
NA |
79 |
68 |
0.9699 |
0.9864 |
| 459 |
G-protein coupled receptor 4 |
CHEMBL3638324 |
NA |
38 |
31 |
1 |
1 |
| 460 |
G-protein coupled receptor 52 |
CHEMBL3297639 |
NA |
154 |
122 |
0.9941 |
1 |
| 461 |
G-protein coupled receptor 55 |
CHEMBL1075322 |
NA |
166 |
80 |
0.9965 |
0.9845 |
| 462 |
G-protein coupled receptor 6 |
CHEMBL3714130 |
NA |
28 |
10 |
0.941 |
0.8094 |
| 463 |
G-protein coupled receptor 84 |
CHEMBL3714079 |
NA |
375 |
270 |
0.9995 |
0.9997 |
| 464 |
GABA A receptor alpha-2/beta-2/gamma-2 |
CHEMBL2111413 |
NA |
87 |
48 |
0.9859 |
0.9835 |
| 465 |
GABA A receptor alpha-3/beta-2/gamma-2 |
CHEMBL2111339 |
NA |
43 |
33 |
0.9912 |
0.9989 |
| 466 |
GABA A receptor alpha-4/beta-3/gamma-2 |
CHEMBL2111366 |
NA |
21 |
17 |
0.9575 |
0.9591 |
| 467 |
GABA-A receptor; alpha-1/beta-2/gamma-2 |
CHEMBL2095172 |
NA |
181 |
111 |
0.9854 |
0.9763 |
| 468 |
GABA-A receptor; alpha-1/beta-3/gamma-2 |
CHEMBL2094121 |
NA |
224 |
195 |
0.9888 |
0.9934 |
| 469 |
GABA-A receptor; alpha-2/beta-3/gamma-2 |
CHEMBL2094130 |
NA |
150 |
136 |
0.9901 |
0.9978 |
| 470 |
GABA-A receptor; alpha-3/beta-3/gamma-2 |
CHEMBL2094120 |
NA |
190 |
177 |
0.9906 |
0.9983 |
| 471 |
GABA-A receptor; alpha-5/beta-3/gamma-2 |
CHEMBL2094122 |
NA |
248 |
241 |
0.992 |
0.997 |
| 472 |
GABA-A receptor; alpha-6/beta-3/gamma-2 |
CHEMBL2095190 |
NA |
18 |
13 |
0.9503 |
0.9558 |
| 473 |
GABA-B receptor |
CHEMBL2111463 |
NA |
40 |
18 |
0.9958 |
0.9884 |
| 474 |
GRIA1/CACNG8 |
CHEMBL4296110 |
NA |
20 |
18 |
0.9626 |
0.9622 |
| 475 |
GTPase KRas |
CHEMBL2189121 |
G13D |
473 |
10 |
0.9861 |
1 |
| 476 |
GTPase KRas |
CHEMBL2189121 |
NA |
473 |
35 |
0.9861 |
0.9957 |
| 477 |
GTPase KRas |
CHEMBL2189121 |
G12D |
473 |
53 |
0.9861 |
0.9977 |
| 478 |
GTPase KRas |
CHEMBL2189121 |
G12C |
473 |
99 |
0.9861 |
0.9999 |
| 479 |
Galectin-3 |
CHEMBL4531 |
NA |
228 |
22 |
0.9996 |
0.9751 |
| 480 |
Galectin-8 |
CHEMBL5475 |
NA |
78 |
10 |
0.9997 |
1 |
| 481 |
Gamma-aminobutyric acid receptor subunit alpha-4/beta3/delta |
CHEMBL3430899 |
NA |
40 |
34 |
1 |
1 |
| 482 |
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 |
CHEMBL4523641 |
NA |
36 |
28 |
0.998 |
0.9958 |
| 483 |
Gamma-aminobutyric acid receptor subunit beta-3 |
CHEMBL1847 |
NA |
16 |
11 |
0.9997 |
1 |
| 484 |
Gamma-aminobutyric acid receptor subunit rho-1 |
CHEMBL3561 |
NA |
36 |
19 |
0.9979 |
0.9994 |
| 485 |
Gamma-secretase |
CHEMBL2094135 |
NA |
2081 |
1668 |
0.9936 |
0.9984 |
| 486 |
Gastric inhibitory polypeptide receptor |
CHEMBL4383 |
NA |
70 |
23 |
0.9997 |
0.9998 |
| 487 |
Gastrin/cholecystokinin type B receptor |
CHEMBL298 |
NA |
227 |
115 |
0.9969 |
0.9993 |
| 488 |
Geranylgeranyl pyrophosphate synthase |
CHEMBL4769 |
NA |
148 |
52 |
0.9998 |
1 |
| 489 |
Geranylgeranyl transferase type I |
CHEMBL2095164 |
NA |
157 |
71 |
0.9845 |
0.9922 |
| 490 |
Glucagon receptor |
CHEMBL1985 |
NA |
545 |
394 |
0.9963 |
0.996 |
| 491 |
Glucagon-like peptide 1 receptor |
CHEMBL1784 |
NA |
203 |
133 |
0.9948 |
0.9948 |
| 492 |
Glucocorticoid receptor |
CHEMBL2034 |
NA |
1938 |
1213 |
0.995 |
0.9974 |
| 493 |
Glucokinase/Glucokinase regulatory protein |
CHEMBL3885579 |
NA |
33 |
28 |
1 |
1 |
| 494 |
Glucose-6-phosphate 1-dehydrogenase |
CHEMBL5347 |
NA |
27 |
10 |
0.9209 |
0.8607 |
| 495 |
Glucose-dependent insulinotropic receptor |
CHEMBL5652 |
NA |
1081 |
873 |
0.9972 |
0.9982 |
| 496 |
Glutamate NMDA receptor; GRIN1/GRIN2A |
CHEMBL1907604 |
NA |
145 |
83 |
0.9878 |
0.9922 |
| 497 |
Glutamate NMDA receptor; GRIN1/GRIN2B |
CHEMBL1907603 |
NA |
192 |
161 |
0.9943 |
0.9985 |
| 498 |
Glutamate carboxypeptidase 2 |
CHEMBL1892 |
NA |
273 |
116 |
0.9963 |
0.9999 |
| 499 |
Glutamate receptor 1 |
CHEMBL2009 |
NA |
32 |
17 |
0.9525 |
0.9983 |
| 500 |
Glutamate receptor 2 |
CHEMBL4016 |
NA |
248 |
89 |
0.9968 |
0.9936 |
| 501 |
Glutamate receptor 4 |
CHEMBL3190 |
NA |
56 |
37 |
0.9906 |
0.9988 |
| 502 |
Glutamate receptor ionotropic, NMDA 1 |
CHEMBL2015 |
NA |
24 |
24 |
0.9841 |
0.9868 |
| 503 |
Glutamate receptor ionotropic, NMDA 2A |
CHEMBL1972 |
NA |
31 |
13 |
0.985 |
0.9758 |
| 504 |
Glutamate receptor ionotropic, NMDA 2B |
CHEMBL1904 |
NA |
173 |
117 |
0.9787 |
0.9972 |
| 505 |
Glutamate receptor ionotropic, kainate 1 |
CHEMBL1918 |
NA |
94 |
15 |
0.9949 |
0.9949 |
| 506 |
Glutamate receptor ionotropic, kainate 2 |
CHEMBL3683 |
NA |
34 |
12 |
0.9704 |
0.9928 |
| 507 |
Glutaminase kidney isoform, mitochondrial |
CHEMBL2146302 |
NA |
356 |
101 |
0.9947 |
0.9999 |
| 508 |
Glutaminyl-peptide cyclotransferase |
CHEMBL4508 |
NA |
629 |
162 |
0.9978 |
0.9963 |
| 509 |
Glutaminyl-peptide cyclotransferase-like protein |
CHEMBL3638349 |
NA |
79 |
24 |
0.9889 |
0.9554 |
| 510 |
Glutathione S-transferase omega-1 |
CHEMBL3174 |
NA |
75 |
19 |
0.9562 |
0.9999 |
| 511 |
Glycine receptor (alpha-1/beta) |
CHEMBL2363052 |
NA |
31 |
19 |
0.9988 |
0.999 |
| 512 |
Glycine receptor subunit alpha-1 |
CHEMBL5845 |
NA |
61 |
28 |
0.931 |
0.9416 |
| 513 |
Glycogen phosphorylase, liver form |
CHEMBL2568 |
NA |
373 |
153 |
0.9958 |
0.9998 |
| 514 |
Glycogen synthase kinase-3 alpha |
CHEMBL2850 |
NA |
254 |
45 |
0.9525 |
0.9976 |
| 515 |
Glycogen synthase kinase-3 beta |
CHEMBL262 |
UNDEFINED MUTATION |
2228 |
103 |
0.9738 |
0.9958 |
| 516 |
Glycogen synthase kinase-3 beta |
CHEMBL262 |
NA |
2228 |
308 |
0.9738 |
0.9763 |
| 517 |
Gonadotropin-releasing hormone receptor |
CHEMBL1855 |
NA |
679 |
391 |
0.9945 |
0.995 |
| 518 |
Group 10 secretory phospholipase A2 |
CHEMBL4342 |
NA |
99 |
16 |
0.9954 |
0.9755 |
| 519 |
Group IID secretory phospholipase A2 |
CHEMBL4281 |
NA |
10 |
10 |
1 |
1 |
| 520 |
Growth hormone secretagogue receptor type 1 |
CHEMBL4616 |
NA |
1003 |
835 |
0.9964 |
0.9982 |
| 521 |
HSP60/HSP10 |
CHEMBL4106131 |
NA |
109 |
44 |
0.9626 |
0.9753 |
| 522 |
Heat shock factor protein 1 |
CHEMBL5869 |
NA |
88 |
44 |
0.9704 |
0.9601 |
| 523 |
Heat shock protein HSP 90-alpha |
CHEMBL3880 |
NA |
913 |
121 |
0.9898 |
0.995 |
| 524 |
Heat shock protein HSP 90-beta |
CHEMBL4303 |
NA |
466 |
71 |
0.9893 |
0.9775 |
| 525 |
Hematopoietic prostaglandin D synthase |
CHEMBL5879 |
NA |
247 |
123 |
0.9891 |
0.9915 |
| 526 |
Heparanase |
CHEMBL3921 |
NA |
201 |
12 |
0.9953 |
0.8956 |
| 527 |
Hepatic sodium/bile acid cotransporter |
CHEMBL5287 |
NA |
49 |
20 |
0.9488 |
0.9925 |
| 528 |
Hepatic triacylglycerol lipase |
CHEMBL2127 |
NA |
45 |
34 |
0.9808 |
0.9741 |
| 529 |
Hepatitis A virus cellular receptor 2 |
CHEMBL4630879 |
NA |
61 |
28 |
0.9862 |
0.9998 |
| 530 |
Hepatocyte growth factor activator |
CHEMBL3351190 |
NA |
105 |
14 |
0.9989 |
0.9984 |
| 531 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
Y1235D |
2745 |
11 |
0.9829 |
0.9989 |
| 532 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
D1228N |
2745 |
16 |
0.9829 |
1 |
| 533 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
Y1230H |
2745 |
25 |
0.9829 |
0.9975 |
| 534 |
Hepatocyte growth factor receptor |
CHEMBL3717 |
NA |
2745 |
537 |
0.9829 |
0.9948 |
| 535 |
Hexokinase-1 |
CHEMBL2688 |
NA |
22 |
12 |
0.9852 |
1 |
| 536 |
Hexokinase-2 |
CHEMBL2640 |
NA |
30 |
17 |
0.9909 |
1 |
| 537 |
Hexokinase-4 |
CHEMBL3820 |
NA |
887 |
187 |
0.9975 |
1 |
| 538 |
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A |
CHEMBL3012 |
NA |
277 |
49 |
0.9818 |
0.9392 |
| 539 |
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A |
CHEMBL4640 |
NA |
29 |
14 |
0.9486 |
0.9967 |
| 540 |
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
CHEMBL3535 |
NA |
139 |
55 |
0.9658 |
0.9823 |
| 541 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
F589L |
1330 |
11 |
0.9748 |
0.95 |
| 542 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
G667C |
1330 |
29 |
0.9748 |
0.9548 |
| 543 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
G595R |
1330 |
36 |
0.9748 |
0.9662 |
| 544 |
High affinity nerve growth factor receptor |
CHEMBL2815 |
NA |
1330 |
459 |
0.9748 |
0.9797 |
| 545 |
Histamine H1 receptor |
CHEMBL231 |
NA |
941 |
592 |
0.9805 |
0.9934 |
| 546 |
Histamine H2 receptor |
CHEMBL1941 |
NA |
280 |
136 |
0.9745 |
0.9919 |
| 547 |
Histamine H3 receptor |
CHEMBL264 |
NA |
2981 |
2185 |
0.9916 |
0.9945 |
| 548 |
Histamine H4 receptor |
CHEMBL3759 |
NA |
830 |
466 |
0.9921 |
0.9974 |
| 549 |
Histone acetyltransferase KAT2B |
CHEMBL5500 |
NA |
153 |
33 |
0.9865 |
0.9823 |
| 550 |
Histone acetyltransferase KAT6A |
CHEMBL3774298 |
NA |
267 |
174 |
0.9984 |
1 |
| 551 |
Histone acetyltransferase p300 |
CHEMBL3784 |
NA |
416 |
73 |
0.9714 |
0.9514 |
| 552 |
Histone deacetylase 1 |
CHEMBL325 |
NA |
4485 |
995 |
0.9924 |
0.9959 |
| 553 |
Histone deacetylase 11 |
CHEMBL3310 |
NA |
345 |
67 |
0.9923 |
0.998 |
| 554 |
Histone deacetylase 2 |
CHEMBL1937 |
NA |
1666 |
337 |
0.9877 |
0.9922 |
| 555 |
Histone deacetylase 3 |
CHEMBL1829 |
NA |
1384 |
278 |
0.9913 |
0.9975 |
| 556 |
Histone deacetylase 3/NCoR1 |
CHEMBL3038484 |
NA |
66 |
55 |
0.9965 |
0.9951 |
| 557 |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) |
CHEMBL2111363 |
NA |
357 |
266 |
0.9948 |
0.9981 |
| 558 |
Histone deacetylase 4 |
CHEMBL3524 |
NA |
581 |
130 |
0.9914 |
0.9954 |
| 559 |
Histone deacetylase 5 |
CHEMBL2563 |
NA |
260 |
53 |
0.9824 |
0.9931 |
| 560 |
Histone deacetylase 6 |
CHEMBL1865 |
NA |
3396 |
1021 |
0.9906 |
0.9965 |
| 561 |
Histone deacetylase 7 |
CHEMBL2716 |
NA |
338 |
65 |
0.9839 |
0.983 |
| 562 |
Histone deacetylase 8 |
CHEMBL3192 |
NA |
1772 |
315 |
0.991 |
0.995 |
| 563 |
Histone deacetylase 9 |
CHEMBL4145 |
NA |
235 |
22 |
0.9821 |
0.9968 |
| 564 |
Histone-arginine methyltransferase CARM1 |
CHEMBL5406 |
NA |
280 |
49 |
0.9873 |
0.9878 |
| 565 |
Histone-lysine N-methyltransferase 2A/WDR5 |
CHEMBL3883320 |
NA |
62 |
40 |
0.9846 |
0.9526 |
| 566 |
Histone-lysine N-methyltransferase EHMT1 |
CHEMBL6031 |
NA |
179 |
84 |
0.9828 |
0.9999 |
| 567 |
Histone-lysine N-methyltransferase EHMT2 |
CHEMBL6032 |
NA |
525 |
114 |
0.9871 |
0.9927 |
| 568 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
Y641F |
638 |
29 |
0.9928 |
1 |
| 569 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
Y641N |
638 |
42 |
0.9928 |
0.9998 |
| 570 |
Histone-lysine N-methyltransferase EZH2 |
CHEMBL2189110 |
NA |
638 |
119 |
0.9928 |
0.9922 |
| 571 |
Histone-lysine N-methyltransferase NSD2 |
CHEMBL3108645 |
NA |
237 |
43 |
0.9688 |
0.9971 |
| 572 |
Histone-lysine N-methyltransferase NSD3 |
CHEMBL3108646 |
NA |
52 |
12 |
0.8871 |
0.9789 |
| 573 |
Histone-lysine N-methyltransferase SETD2 |
CHEMBL3108647 |
NA |
28 |
20 |
0.9704 |
1 |
| 574 |
Histone-lysine N-methyltransferase SMYD3 |
CHEMBL2321643 |
NA |
124 |
75 |
0.9884 |
1 |
| 575 |
Histone-lysine N-methyltransferase, H3 lysine-79 specific |
CHEMBL1795117 |
NA |
158 |
25 |
0.9869 |
0.9965 |
| 576 |
Hormone-sensitive lipase |
CHEMBL3590 |
NA |
64 |
31 |
0.9999 |
1 |
| 577 |
Hydroxycarboxylic acid receptor 1 |
CHEMBL1075101 |
NA |
37 |
29 |
0.9998 |
1 |
| 578 |
Hydroxycarboxylic acid receptor 2 |
CHEMBL3785 |
NA |
467 |
227 |
0.9976 |
0.9992 |
| 579 |
Hydroxycarboxylic acid receptor 3 |
CHEMBL4421 |
NA |
98 |
48 |
0.9975 |
0.9994 |
| 580 |
Hypoxia-inducible factor 1-alpha |
CHEMBL4261 |
NA |
416 |
203 |
0.9816 |
0.9784 |
| 581 |
IKK epsilon/TBK1 |
CHEMBL3038486 |
NA |
21 |
11 |
1 |
1 |
| 582 |
Ileal sodium/bile acid cotransporter |
CHEMBL2778 |
NA |
163 |
113 |
0.9999 |
0.9999 |
| 583 |
Immunoglobulin lambda variable 6-57 |
CHEMBL4739844 |
NA |
40 |
23 |
1 |
1 |
| 584 |
Indoleamine 2,3-dioxygenase 1 |
CHEMBL4685 |
S167A |
2114 |
10 |
0.9823 |
0.9458 |
| 585 |
Indoleamine 2,3-dioxygenase 1 |
CHEMBL4685 |
NA |
2114 |
859 |
0.9823 |
0.992 |
| 586 |
Indoleamine 2,3-dioxygenase 2 |
CHEMBL3627587 |
NA |
50 |
11 |
0.9812 |
0.9996 |
| 587 |
Induced myeloid leukemia cell differentiation protein Mcl-1 |
CHEMBL4361 |
NA |
1220 |
340 |
0.9898 |
0.9959 |
| 588 |
Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist |
CHEMBL3430886 |
NA |
37 |
14 |
0.9275 |
0.9157 |
| 589 |
Induced myeloid leukemia cell differentiation protein Mcl-1/Bcl-2-like protein 11 |
CHEMBL3430887 |
NA |
72 |
25 |
0.9852 |
0.9765 |
| 590 |
Inhibitor of NF-kappa-B kinase (IKK) |
CHEMBL2111328 |
NA |
20 |
13 |
0.9914 |
1 |
| 591 |
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
CHEMBL3476 |
NA |
173 |
20 |
0.9789 |
0.9929 |
| 592 |
Inhibitor of nuclear factor kappa-B kinase subunit beta |
CHEMBL1991 |
NA |
601 |
39 |
0.9744 |
0.9727 |
| 593 |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon |
CHEMBL3529 |
NA |
131 |
37 |
0.9781 |
0.9892 |
| 594 |
Inositol hexakisphosphate kinase 1 |
CHEMBL4523418 |
NA |
157 |
27 |
0.9999 |
0.9801 |
| 595 |
Inositol hexakisphosphate kinase 2 |
CHEMBL4523488 |
NA |
58 |
27 |
0.996 |
1 |
| 596 |
Inositol hexakisphosphate kinase 3 |
CHEMBL4523431 |
NA |
48 |
13 |
0.9984 |
1 |
| 597 |
Insulin receptor |
CHEMBL1981 |
NA |
275 |
41 |
0.9635 |
0.9959 |
| 598 |
Insulin-like growth factor 1 receptor |
CHEMBL1957 |
NA |
645 |
257 |
0.9799 |
0.991 |
| 599 |
Integrin alpha-2/beta-3 |
CHEMBL2111461 |
NA |
18 |
16 |
0.995 |
1 |
| 600 |
Integrin alpha-4 |
CHEMBL278 |
NA |
117 |
88 |
0.9999 |
0.9999 |
| 601 |
Integrin alpha-4/beta-1 |
CHEMBL1907599 |
NA |
589 |
456 |
0.9995 |
0.9993 |
| 602 |
Integrin alpha-4/beta-7 |
CHEMBL2095184 |
NA |
201 |
173 |
0.9994 |
0.9994 |
| 603 |
Integrin alpha-5/beta-1 |
CHEMBL2095226 |
NA |
216 |
159 |
0.9912 |
0.9981 |
| 604 |
Integrin alpha-IIb/beta-3 |
CHEMBL2093869 |
NA |
971 |
644 |
0.9973 |
0.9979 |
| 605 |
Integrin alpha-L |
CHEMBL1803 |
NA |
79 |
32 |
0.9817 |
1 |
| 606 |
Integrin alpha-V/beta-1 |
CHEMBL2111407 |
NA |
110 |
98 |
0.9986 |
0.9985 |
| 607 |
Integrin alpha-V/beta-3 |
CHEMBL1907598 |
NA |
725 |
626 |
0.9924 |
0.9941 |
| 608 |
Integrin alpha-V/beta-5 |
CHEMBL2096675 |
NA |
242 |
202 |
0.999 |
0.9986 |
| 609 |
Integrin alpha-V/beta-6 |
CHEMBL2111416 |
NA |
243 |
180 |
0.9994 |
0.9989 |
| 610 |
Integrin alpha-V/beta-8 |
CHEMBL3430892 |
NA |
116 |
93 |
0.9992 |
0.9989 |
| 611 |
Integrin alpha2/beta1 |
CHEMBL3137268 |
NA |
44 |
40 |
0.9955 |
0.9989 |
| 612 |
Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2 |
CHEMBL2096661 |
NA |
173 |
155 |
0.9962 |
0.9964 |
| 613 |
Interleukin-1 receptor antagonist protein |
CHEMBL4523191 |
NA |
63 |
23 |
0.9926 |
0.9994 |
| 614 |
Interleukin-1 receptor-associated kinase 1 |
CHEMBL3357 |
NA |
63 |
11 |
0.9176 |
0.9239 |
| 615 |
Interleukin-1 receptor-associated kinase 3 |
CHEMBL5081 |
NA |
31 |
16 |
0.8975 |
0.9041 |
| 616 |
Interleukin-1 receptor-associated kinase 4 |
CHEMBL3778 |
NA |
907 |
344 |
0.9943 |
0.9983 |
| 617 |
Interleukin-17A |
CHEMBL3390822 |
NA |
26 |
18 |
0.9557 |
0.9731 |
| 618 |
Interleukin-2 |
CHEMBL5880 |
NA |
81 |
43 |
0.9649 |
0.9622 |
| 619 |
Intermediate conductance calcium-activated potassium channel protein 4 |
CHEMBL4305 |
NA |
47 |
18 |
0.9995 |
1 |
| 620 |
Interstitial collagenase |
CHEMBL332 |
NA |
715 |
31 |
0.9873 |
0.9973 |
| 621 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
R132L |
722 |
10 |
0.991 |
0.9961 |
| 622 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
NA |
722 |
22 |
0.991 |
0.9453 |
| 623 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
R132C |
722 |
121 |
0.991 |
0.9938 |
| 624 |
Isocitrate dehydrogenase [NADP] cytoplasmic |
CHEMBL2007625 |
R132H |
722 |
224 |
0.991 |
0.9898 |
| 625 |
Isocitrate dehydrogenase [NADP], mitochondrial |
CHEMBL3991501 |
R140Q |
103 |
18 |
0.9968 |
1 |
| 626 |
JAK1/JAK2/TYK2 |
CHEMBL3301390 |
NA |
27 |
25 |
0.9695 |
0.9757 |
| 627 |
JAK1/TYK2 |
CHEMBL3301391 |
NA |
127 |
106 |
0.9909 |
0.9928 |
| 628 |
JAK2/JAK1 |
CHEMBL3038492 |
NA |
51 |
30 |
0.9815 |
0.9782 |
| 629 |
JAK2/TYK2 |
CHEMBL3301392 |
NA |
46 |
33 |
0.982 |
0.9884 |
| 630 |
JAK3/JAK1 |
CHEMBL3038491 |
NA |
185 |
161 |
0.9933 |
0.9909 |
| 631 |
Kallikrein-5 |
CHEMBL4447 |
NA |
112 |
45 |
0.9891 |
0.9999 |
| 632 |
Kallikrein-6 |
CHEMBL4448 |
NA |
44 |
21 |
0.961 |
0.9615 |
| 633 |
Kallikrein-7 |
CHEMBL2443 |
NA |
138 |
16 |
0.9762 |
1 |
| 634 |
Kallikrein-8 |
CHEMBL4812 |
NA |
21 |
12 |
0.9995 |
0.9996 |
| 635 |
Kappa-type opioid receptor |
CHEMBL237 |
NA |
2807 |
2081 |
0.9829 |
0.991 |
| 636 |
Keap1/Nrf2 |
CHEMBL3038498 |
NA |
524 |
202 |
0.9864 |
0.9931 |
| 637 |
Kelch-like ECH-associated protein 1 |
CHEMBL2069156 |
NA |
358 |
85 |
0.9795 |
0.998 |
| 638 |
Ketohexokinase |
CHEMBL1275212 |
NA |
76 |
45 |
0.9995 |
1 |
| 639 |
KiSS-1 receptor |
CHEMBL5413 |
NA |
153 |
146 |
0.9973 |
0.9993 |
| 640 |
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET |
CHEMBL3430888 |
NA |
82 |
46 |
0.9844 |
0.9733 |
| 641 |
Kinesin-like protein KIF11 |
CHEMBL4581 |
NA |
716 |
193 |
0.9935 |
0.996 |
| 642 |
Kinesin-like protein KIF18A |
CHEMBL4523403 |
NA |
41 |
33 |
0.9994 |
0.9986 |
| 643 |
Kir3.1/Kir3.2 |
CHEMBL3038489 |
NA |
180 |
95 |
0.997 |
0.9973 |
| 644 |
Kir3.1/Kir3.4 |
CHEMBL3038488 |
NA |
178 |
77 |
0.9997 |
0.9997 |
| 645 |
Kynurenine 3-monooxygenase |
CHEMBL2145 |
NA |
179 |
96 |
0.998 |
0.9999 |
| 646 |
L-amino-acid oxidase |
CHEMBL5291590 |
NA |
20 |
14 |
1 |
1 |
| 647 |
L-lactate dehydrogenase A chain |
CHEMBL4835 |
NA |
520 |
125 |
0.9776 |
0.9884 |
| 648 |
L-lactate dehydrogenase B chain |
CHEMBL4940 |
NA |
186 |
21 |
0.9925 |
0.9845 |
| 649 |
LIM domain kinase 1 |
CHEMBL3836 |
NA |
301 |
48 |
0.9703 |
0.9509 |
| 650 |
LIM domain kinase 2 |
CHEMBL5932 |
NA |
263 |
85 |
0.9719 |
0.9754 |
| 651 |
LSD1/CoREST complex |
CHEMBL3137262 |
NA |
183 |
130 |
0.9937 |
0.9949 |
| 652 |
Lactoylglutathione lyase |
CHEMBL2424 |
NA |
146 |
42 |
0.9927 |
0.9996 |
| 653 |
Lanosterol synthase |
CHEMBL3593 |
NA |
47 |
24 |
0.978 |
0.999 |
| 654 |
Legumain |
CHEMBL4244 |
NA |
171 |
31 |
0.9998 |
1 |
| 655 |
Leucine-rich repeat serine/threonine-protein kinase 2 |
CHEMBL1075104 |
G2019S |
984 |
250 |
0.9876 |
0.9916 |
| 656 |
Leucine-rich repeat serine/threonine-protein kinase 2 |
CHEMBL1075104 |
NA |
984 |
258 |
0.9876 |
0.9956 |
| 657 |
Leucyl-cystinyl aminopeptidase |
CHEMBL2693 |
NA |
170 |
56 |
0.9877 |
0.9994 |
| 658 |
Leukotriene A-4 hydrolase |
CHEMBL4618 |
NA |
311 |
95 |
0.9961 |
0.9964 |
| 659 |
Leukotriene B4 receptor 2 |
CHEMBL3191 |
NA |
68 |
52 |
0.9942 |
0.9944 |
| 660 |
Leukotriene C4 synthase |
CHEMBL1743183 |
NA |
47 |
33 |
0.9907 |
0.9998 |
| 661 |
Liver carboxylesterase 1 |
CHEMBL2265 |
NA |
169 |
72 |
0.9909 |
0.9996 |
| 662 |
Long-chain fatty acid transport protein 4 |
CHEMBL4327 |
NA |
24 |
10 |
1 |
1 |
| 663 |
Low molecular weight phosphotyrosine protein phosphatase |
CHEMBL4903 |
NA |
158 |
37 |
0.9933 |
0.9999 |
| 664 |
Lutropin-choriogonadotropic hormone receptor |
CHEMBL1854 |
NA |
51 |
31 |
0.964 |
0.9756 |
| 665 |
Lysine-specific demethylase 2A |
CHEMBL1938210 |
NA |
100 |
16 |
0.9889 |
0.9674 |
| 666 |
Lysine-specific demethylase 4A |
CHEMBL5896 |
NA |
182 |
65 |
0.978 |
0.9975 |
| 667 |
Lysine-specific demethylase 4B |
CHEMBL3313832 |
NA |
103 |
68 |
0.9902 |
0.9977 |
| 668 |
Lysine-specific demethylase 4C |
CHEMBL6175 |
NA |
226 |
52 |
0.9861 |
0.976 |
| 669 |
Lysine-specific demethylase 4D |
CHEMBL6138 |
NA |
97 |
53 |
0.992 |
0.9999 |
| 670 |
Lysine-specific demethylase 4E |
CHEMBL1293226 |
NA |
91 |
19 |
0.9839 |
0.9949 |
| 671 |
Lysine-specific demethylase 5A |
CHEMBL2424504 |
NA |
219 |
49 |
0.9841 |
0.9884 |
| 672 |
Lysine-specific demethylase 5B |
CHEMBL3774295 |
NA |
290 |
42 |
0.9954 |
0.9918 |
| 673 |
Lysine-specific histone demethylase 1A |
CHEMBL6136 |
NA |
1407 |
382 |
0.9801 |
0.9896 |
| 674 |
Lysophosphatidic acid receptor 1 |
CHEMBL3819 |
NA |
268 |
163 |
0.9962 |
0.9966 |
| 675 |
Lysophosphatidic acid receptor 2 |
CHEMBL3724 |
NA |
103 |
40 |
0.9954 |
0.9999 |
| 676 |
Lysophosphatidic acid receptor 3 |
CHEMBL3250 |
NA |
60 |
36 |
0.9763 |
0.9885 |
| 677 |
Lysophosphatidic acid receptor 5 |
CHEMBL5700 |
NA |
53 |
38 |
0.9989 |
0.9941 |
| 678 |
Lysosomal acid glucosylceramidase |
CHEMBL2179 |
NA |
277 |
14 |
0.9957 |
0.9354 |
| 679 |
Lysosomal acid glucosylceramidase |
CHEMBL2179 |
N409S |
277 |
45 |
0.9957 |
0.9943 |
| 680 |
Lysyl oxidase homolog 2 |
CHEMBL3714029 |
NA |
125 |
93 |
0.9939 |
0.9975 |
| 681 |
Lysyl oxidase homolog 3 |
CHEMBL4105989 |
NA |
25 |
13 |
0.9771 |
0.9922 |
| 682 |
M-phase inducer phosphatase 1 |
CHEMBL3775 |
NA |
204 |
24 |
0.9907 |
0.9932 |
| 683 |
M-phase inducer phosphatase 2 |
CHEMBL4804 |
NA |
309 |
41 |
0.987 |
0.9953 |
| 684 |
M-phase inducer phosphatase 3 |
CHEMBL2378 |
NA |
89 |
11 |
0.9935 |
0.9972 |
| 685 |
MAP kinase-activated protein kinase 2 |
CHEMBL2208 |
NA |
547 |
69 |
0.9883 |
0.9872 |
| 686 |
MAP kinase-activated protein kinase 5 |
CHEMBL3094 |
NA |
27 |
10 |
0.8843 |
0.9832 |
| 687 |
MAP kinase-interacting serine/threonine-protein kinase 1 |
CHEMBL4718 |
NA |
442 |
121 |
0.9808 |
0.9787 |
| 688 |
MAP kinase-interacting serine/threonine-protein kinase 2 |
CHEMBL4204 |
NA |
412 |
150 |
0.9792 |
0.9895 |
| 689 |
MAP/microtubule affinity-regulating kinase 3 |
CHEMBL5600 |
NA |
73 |
25 |
0.9722 |
0.9865 |
| 690 |
MAP/microtubule affinity-regulating kinase 4 |
CHEMBL5754 |
NA |
71 |
26 |
0.9469 |
0.9745 |
| 691 |
METTL3/METTL14 |
CHEMBL4106140 |
NA |
34 |
15 |
0.9963 |
0.9847 |
| 692 |
MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) |
CHEMBL2111430 |
NA |
17 |
10 |
0.9731 |
0.9678 |
| 693 |
MLL1-ASH2L/RbBP5/WDR5/DPY30 |
CHEMBL4106124 |
NA |
30 |
28 |
0.9998 |
0.9998 |
| 694 |
Macrophage colony-stimulating factor 1 receptor |
CHEMBL1844 |
NA |
872 |
245 |
0.98 |
0.9832 |
| 695 |
Macrophage metalloelastase |
CHEMBL4393 |
UNDEFINED MUTATION |
383 |
13 |
0.9913 |
1 |
| 696 |
Macrophage metalloelastase |
CHEMBL4393 |
NA |
383 |
48 |
0.9913 |
0.9977 |
| 697 |
Macrophage migration inhibitory factor |
CHEMBL2085 |
NA |
291 |
70 |
0.9692 |
0.9853 |
| 698 |
Macrophage-stimulating protein receptor |
CHEMBL2689 |
NA |
103 |
44 |
0.9722 |
0.9874 |
| 699 |
Malate dehydrogenase, cytoplasmic |
CHEMBL3560 |
NA |
22 |
13 |
0.9811 |
1 |
| 700 |
Mas-related G-protein coupled receptor member X1 |
CHEMBL5850 |
NA |
115 |
73 |
0.9947 |
0.9919 |
| 701 |
Mas-related G-protein coupled receptor member X2 |
CHEMBL5849 |
NA |
36 |
14 |
0.9554 |
0.889 |
| 702 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
D816H |
797 |
11 |
0.972 |
0.88 |
| 703 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
V559D,T670I |
797 |
17 |
0.972 |
0.8936 |
| 704 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
UNDEFINED MUTATION |
797 |
25 |
0.972 |
0.9559 |
| 705 |
Mast/stem cell growth factor receptor Kit |
CHEMBL1936 |
NA |
797 |
127 |
0.972 |
0.954 |
| 706 |
Maternal embryonic leucine zipper kinase |
CHEMBL4578 |
NA |
131 |
45 |
0.9411 |
0.9141 |
| 707 |
Matrix metalloproteinase-14 |
CHEMBL3869 |
NA |
505 |
11 |
0.9894 |
0.9878 |
| 708 |
Matrix metalloproteinase-9 |
CHEMBL321 |
Q279R |
1176 |
14 |
0.9774 |
1 |
| 709 |
Matrix metalloproteinase-9 |
CHEMBL321 |
NA |
1176 |
40 |
0.9774 |
0.9492 |
| 710 |
Melanin-concentrating hormone receptor 1 |
CHEMBL344 |
NA |
2557 |
1987 |
0.9929 |
0.9952 |
| 711 |
Melanin-concentrating hormone receptor 2 |
CHEMBL5038 |
NA |
42 |
32 |
0.9909 |
0.9999 |
| 712 |
Melanocortin receptor 3 |
CHEMBL4644 |
NA |
484 |
331 |
0.995 |
0.9922 |
| 713 |
Melanocortin receptor 4 |
CHEMBL259 |
L106P |
1704 |
28 |
0.9974 |
0.9999 |
| 714 |
Melanocortin receptor 4 |
CHEMBL259 |
NA |
1704 |
1342 |
0.9974 |
0.9978 |
| 715 |
Melanocortin receptor 5 |
CHEMBL4608 |
NA |
330 |
231 |
0.9958 |
0.992 |
| 716 |
Melanocyte-stimulating hormone receptor |
CHEMBL3795 |
NA |
417 |
278 |
0.9963 |
0.9967 |
| 717 |
Melatonin receptor type 1A |
CHEMBL1945 |
NA |
625 |
513 |
0.9941 |
0.999 |
| 718 |
Melatonin receptor type 1B |
CHEMBL1946 |
NA |
675 |
549 |
0.9955 |
0.9979 |
| 719 |
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase |
CHEMBL3984 |
NA |
75 |
49 |
0.9956 |
0.9922 |
| 720 |
Membrane-bound transcription factor site-1 protease |
CHEMBL5916 |
NA |
21 |
14 |
0.9999 |
1 |
| 721 |
Menin |
CHEMBL1615381 |
NA |
166 |
45 |
0.9928 |
0.9999 |
| 722 |
Menin/Histone-lysine N-methyltransferase MLL |
CHEMBL2093861 |
NA |
135 |
96 |
0.9929 |
0.9927 |
| 723 |
Meprin A subunit beta |
CHEMBL4105879 |
NA |
81 |
45 |
0.9937 |
0.9945 |
| 724 |
Metabotropic glutamate receptor 1 |
CHEMBL3772 |
NA |
436 |
300 |
0.9925 |
0.9968 |
| 725 |
Metabotropic glutamate receptor 2 |
CHEMBL5137 |
NA |
819 |
623 |
0.9962 |
0.9978 |
| 726 |
Metabotropic glutamate receptor 3 |
CHEMBL2888 |
NA |
93 |
80 |
0.9836 |
0.9936 |
| 727 |
Metabotropic glutamate receptor 4 |
CHEMBL2736 |
NA |
500 |
261 |
0.9962 |
0.9993 |
| 728 |
Metabotropic glutamate receptor 5 |
CHEMBL3227 |
NA |
1445 |
1053 |
0.9945 |
0.9962 |
| 729 |
Metabotropic glutamate receptor 6 |
CHEMBL4573 |
NA |
30 |
17 |
0.9961 |
0.9995 |
| 730 |
Metabotropic glutamate receptor 7 |
CHEMBL3777 |
NA |
56 |
25 |
0.933 |
0.9989 |
| 731 |
Metabotropic glutamate receptor 8 |
CHEMBL3228 |
NA |
67 |
32 |
0.9774 |
0.9953 |
| 732 |
Methionine aminopeptidase 1 |
CHEMBL2474 |
NA |
145 |
36 |
0.9956 |
0.9987 |
| 733 |
Methionine aminopeptidase 2 |
CHEMBL3922 |
NA |
411 |
96 |
0.9985 |
0.9909 |
| 734 |
Methylated-DNA--protein-cysteine methyltransferase |
CHEMBL2864 |
NA |
31 |
10 |
0.9963 |
1 |
| 735 |
Microsomal triglyceride transfer protein large subunit |
CHEMBL2569 |
NA |
49 |
40 |
1 |
1 |
| 736 |
Microtubule-associated protein tau |
CHEMBL1293224 |
NA |
232 |
97 |
0.9892 |
0.9922 |
| 737 |
Mineralocorticoid receptor |
CHEMBL1994 |
C808S |
586 |
18 |
0.9971 |
1 |
| 738 |
Mineralocorticoid receptor |
CHEMBL1994 |
NA |
586 |
221 |
0.9971 |
0.9969 |
| 739 |
Mitogen-activated protein kinase 1 |
CHEMBL4040 |
NA |
662 |
178 |
0.9688 |
0.9902 |
| 740 |
Mitogen-activated protein kinase 10 |
CHEMBL2637 |
NA |
690 |
66 |
0.9836 |
0.9836 |
| 741 |
Mitogen-activated protein kinase 11 |
CHEMBL3961 |
NA |
143 |
47 |
0.9825 |
0.9945 |
| 742 |
Mitogen-activated protein kinase 14 |
CHEMBL260 |
NA |
2452 |
468 |
0.988 |
0.9943 |
| 743 |
Mitogen-activated protein kinase 3 |
CHEMBL3385 |
NA |
129 |
23 |
0.9395 |
0.9964 |
| 744 |
Mitogen-activated protein kinase 7 |
CHEMBL5332 |
NA |
140 |
58 |
0.9819 |
0.9999 |
| 745 |
Mitogen-activated protein kinase 8 |
CHEMBL2276 |
NA |
761 |
74 |
0.9831 |
0.9885 |
| 746 |
Mitogen-activated protein kinase 9 |
CHEMBL4179 |
NA |
409 |
60 |
0.9689 |
0.9876 |
| 747 |
Mitogen-activated protein kinase kinase kinase 11 |
CHEMBL2708 |
NA |
66 |
13 |
0.9658 |
0.9999 |
| 748 |
Mitogen-activated protein kinase kinase kinase 12 |
CHEMBL1908389 |
NA |
105 |
79 |
0.993 |
1 |
| 749 |
Mitogen-activated protein kinase kinase kinase 13 |
CHEMBL1163124 |
NA |
24 |
21 |
0.9998 |
1 |
| 750 |
Mitogen-activated protein kinase kinase kinase 14 |
CHEMBL5888 |
S549D |
269 |
11 |
0.9985 |
0.9955 |
| 751 |
Mitogen-activated protein kinase kinase kinase 14 |
CHEMBL5888 |
NA |
269 |
87 |
0.9985 |
0.9992 |
| 752 |
Mitogen-activated protein kinase kinase kinase 20 |
CHEMBL3886 |
NA |
88 |
40 |
0.9408 |
0.9799 |
| 753 |
Mitogen-activated protein kinase kinase kinase 5 |
CHEMBL5285 |
NA |
347 |
128 |
0.9942 |
0.9978 |
| 754 |
Mitogen-activated protein kinase kinase kinase 7 |
CHEMBL5776 |
NA |
204 |
68 |
0.9837 |
0.9758 |
| 755 |
Mitogen-activated protein kinase kinase kinase 8 |
CHEMBL4899 |
NA |
137 |
24 |
0.9896 |
1 |
| 756 |
Mitogen-activated protein kinase kinase kinase 9 |
CHEMBL2872 |
NA |
66 |
16 |
0.9114 |
1 |
| 757 |
Mitogen-activated protein kinase kinase kinase kinase 1 |
CHEMBL5749 |
NA |
480 |
212 |
0.9877 |
0.9973 |
| 758 |
Mitogen-activated protein kinase kinase kinase kinase 4 |
CHEMBL6166 |
NA |
186 |
50 |
0.9606 |
0.9812 |
| 759 |
Monoacylglycerol lipase ABHD6 |
CHEMBL2189127 |
NA |
83 |
35 |
0.9678 |
0.9478 |
| 760 |
Monocarboxylate transporter 1 |
CHEMBL4360 |
NA |
86 |
50 |
0.9789 |
0.9973 |
| 761 |
Monocarboxylate transporter 4 |
CHEMBL2073663 |
NA |
104 |
47 |
0.9836 |
0.9778 |
| 762 |
Monoglyceride lipase |
CHEMBL4191 |
NA |
906 |
236 |
0.9926 |
0.9956 |
| 763 |
Motilin receptor |
CHEMBL2203 |
NA |
184 |
129 |
0.9925 |
0.9922 |
| 764 |
Mu-type opioid receptor |
CHEMBL233 |
NA |
3321 |
2512 |
0.9841 |
0.9916 |
| 765 |
Mucolipin-2 |
CHEMBL4879493 |
NA |
27 |
16 |
0.9999 |
1 |
| 766 |
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
CHEMBL3632452 |
NA |
349 |
109 |
0.9934 |
0.9827 |
| 767 |
Multidrug and toxin extrusion protein 1 |
CHEMBL1743126 |
NA |
41 |
22 |
0.7283 |
0.6676 |
| 768 |
Multidrug and toxin extrusion protein 2 |
CHEMBL1743127 |
NA |
23 |
10 |
0.6669 |
0.6991 |
| 769 |
Multidrug resistance-associated protein 1 |
CHEMBL3004 |
NA |
242 |
135 |
0.9617 |
0.9712 |
| 770 |
Muscarinic acetylcholine receptor M1 |
CHEMBL216 |
NA |
1285 |
788 |
0.9811 |
0.9861 |
| 771 |
Muscarinic acetylcholine receptor M2 |
CHEMBL211 |
NA |
666 |
409 |
0.9714 |
0.9859 |
| 772 |
Muscarinic acetylcholine receptor M3 |
CHEMBL245 |
NA |
970 |
606 |
0.985 |
0.9912 |
| 773 |
Muscarinic acetylcholine receptor M4 |
CHEMBL1821 |
NA |
948 |
645 |
0.9881 |
0.9913 |
| 774 |
Muscarinic acetylcholine receptor M5 |
CHEMBL2035 |
NA |
562 |
272 |
0.9785 |
0.9846 |
| 775 |
Myc proto-oncogene protein |
CHEMBL1250348 |
NA |
53 |
21 |
0.9756 |
0.9989 |
| 776 |
Myeloperoxidase |
CHEMBL2439 |
NA |
303 |
29 |
0.9794 |
1 |
| 777 |
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D |
CHEMBL4630839 |
NA |
98 |
60 |
0.9662 |
0.9991 |
| 778 |
N-acylethanolamine-hydrolyzing acid amidase |
CHEMBL4349 |
NA |
217 |
76 |
0.9965 |
0.998 |
| 779 |
N-alpha-acetyltransferase 50 |
CHEMBL4630854 |
NA |
17 |
10 |
0.9583 |
1 |
| 780 |
N-arachidonyl glycine receptor |
CHEMBL2384898 |
NA |
90 |
48 |
0.9867 |
0.9966 |
| 781 |
N-formyl peptide receptor 2 |
CHEMBL4227 |
NA |
374 |
267 |
0.9961 |
0.997 |
| 782 |
N-lysine methyltransferase SMYD2 |
CHEMBL2169716 |
NA |
113 |
34 |
0.9973 |
0.9993 |
| 783 |
N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
CHEMBL4523442 |
NA |
82 |
28 |
0.9972 |
0.9977 |
| 784 |
N6-adenosine-methyltransferase catalytic subunit |
CHEMBL4739695 |
NA |
36 |
16 |
0.9496 |
0.9832 |
| 785 |
NACHT, LRR and PYD domains-containing protein 3 |
CHEMBL1741208 |
NA |
541 |
265 |
0.9926 |
0.9926 |
| 786 |
NAD-dependent protein deacetylase sirtuin-1 |
CHEMBL4506 |
NA |
566 |
192 |
0.9801 |
0.9872 |
| 787 |
NAD-dependent protein deacetylase sirtuin-2 |
CHEMBL4462 |
NA |
764 |
113 |
0.9818 |
0.9899 |
| 788 |
NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
CHEMBL4461 |
NA |
252 |
86 |
0.9812 |
0.9968 |
| 789 |
NAD-dependent protein deacylase sirtuin-5, mitochondrial |
CHEMBL2163183 |
NA |
284 |
22 |
0.9882 |
1 |
| 790 |
NADPH oxidase 1 |
CHEMBL1287628 |
NA |
50 |
24 |
0.9427 |
0.9013 |
| 791 |
NADPH oxidase 4 |
CHEMBL1250375 |
NA |
127 |
64 |
0.9746 |
1 |
| 792 |
NADPH oxidase 5 |
CHEMBL1926497 |
NA |
32 |
16 |
0.9643 |
0.9999 |
| 793 |
NEDD8 activating enzyme |
CHEMBL3831283 |
NA |
75 |
73 |
0.9974 |
1 |
| 794 |
NF-kappa-B inhibitor alpha |
CHEMBL2898 |
NA |
38 |
13 |
0.9832 |
0.956 |
| 795 |
NKGD2-MICA |
CHEMBL5483005 |
NA |
30 |
20 |
1 |
1 |
| 796 |
NKGD2-ULBP6 |
CHEMBL5483006 |
NA |
28 |
11 |
1 |
1 |
| 797 |
NPC1-like intracellular cholesterol transporter 1 |
CHEMBL2027 |
I1061T |
129 |
10 |
0.9955 |
1 |
| 798 |
NPC1-like intracellular cholesterol transporter 1 |
CHEMBL2027 |
NA |
129 |
49 |
0.9955 |
0.9936 |
| 799 |
NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor) |
CHEMBL2111387 |
NA |
59 |
42 |
0.9961 |
0.9994 |
| 800 |
NT-3 growth factor receptor |
CHEMBL5608 |
NA |
317 |
91 |
0.9791 |
0.9853 |
| 801 |
NUAK family SNF1-like kinase 1 |
CHEMBL5784 |
NA |
74 |
23 |
0.9295 |
0.946 |
| 802 |
Na(+)/citrate cotransporter |
CHEMBL3769293 |
NA |
26 |
22 |
0.9691 |
0.9659 |
| 803 |
Natural resistance-associated macrophage protein 2 |
CHEMBL1932895 |
NA |
43 |
31 |
0.9999 |
0.9973 |
| 804 |
Neprilysin |
CHEMBL1944 |
NA |
203 |
32 |
0.9935 |
0.9876 |
| 805 |
Neurogenic locus notch homolog protein 1 |
CHEMBL2146346 |
NA |
44 |
30 |
1 |
1 |
| 806 |
Neurogenic locus notch homolog protein 3 |
CHEMBL3407319 |
NA |
20 |
19 |
1 |
1 |
| 807 |
Neuromedin-B receptor |
CHEMBL3636 |
NA |
35 |
18 |
0.9736 |
0.9523 |
| 808 |
Neuromedin-K receptor |
CHEMBL4429 |
NA |
329 |
254 |
0.9956 |
0.9968 |
| 809 |
Neuromedin-U receptor 1 |
CHEMBL1075178 |
NA |
48 |
47 |
1 |
0.9999 |
| 810 |
Neuromedin-U receptor 2 |
CHEMBL1075144 |
NA |
75 |
63 |
0.9967 |
0.9999 |
| 811 |
Neuronal acetylcholine receptor subunit alpha-7 |
CHEMBL2492 |
NA |
719 |
319 |
0.9832 |
0.992 |
| 812 |
Neuronal acetylcholine receptor; alpha3/beta4 |
CHEMBL1907594 |
NA |
398 |
195 |
0.9943 |
0.9975 |
| 813 |
Neuronal acetylcholine receptor; alpha4/beta2 |
CHEMBL1907589 |
NA |
675 |
414 |
0.9943 |
0.9952 |
| 814 |
Neuronal acetylcholine receptor; alpha4/beta4 |
CHEMBL1907591 |
NA |
41 |
16 |
0.9919 |
0.977 |
| 815 |
Neuropeptide FF receptor 1 |
CHEMBL5951 |
NA |
135 |
106 |
0.9966 |
0.9964 |
| 816 |
Neuropeptide FF receptor 2 |
CHEMBL5952 |
NA |
143 |
91 |
0.9969 |
0.9973 |
| 817 |
Neuropeptide S receptor |
CHEMBL5162 |
NA |
60 |
45 |
0.9917 |
0.9976 |
| 818 |
Neuropeptide Y receptor type 1 |
CHEMBL4777 |
NA |
256 |
207 |
0.9939 |
0.9972 |
| 819 |
Neuropeptide Y receptor type 2 |
CHEMBL4018 |
NA |
164 |
88 |
0.9827 |
0.9868 |
| 820 |
Neuropeptide Y receptor type 4 |
CHEMBL4877 |
NA |
70 |
48 |
0.9779 |
0.9897 |
| 821 |
Neuropeptide Y receptor type 5 |
CHEMBL4561 |
NA |
449 |
317 |
0.9952 |
0.9968 |
| 822 |
Neuropeptides B/W receptor type 1 |
CHEMBL1293293 |
NA |
114 |
60 |
0.9999 |
0.9999 |
| 823 |
Neurotensin receptor type 1 |
CHEMBL4123 |
NA |
180 |
109 |
0.9952 |
0.9984 |
| 824 |
Neurotensin receptor type 2 |
CHEMBL2514 |
NA |
78 |
63 |
0.9991 |
0.9992 |
| 825 |
Neutrophil collagenase |
CHEMBL4588 |
NA |
461 |
36 |
0.9867 |
0.9815 |
| 826 |
Neutrophil cytosol factor 1 |
CHEMBL1613743 |
NA |
97 |
35 |
0.9871 |
1 |
| 827 |
Nicotinamide N-methyltransferase |
CHEMBL2346486 |
NA |
180 |
55 |
0.9951 |
0.9987 |
| 828 |
Nicotinamide phosphoribosyltransferase |
CHEMBL1744525 |
NA |
753 |
230 |
0.9947 |
0.9977 |
| 829 |
Nischarin |
CHEMBL3923 |
NA |
30 |
19 |
0.9954 |
0.9944 |
| 830 |
Nitric oxide synthase 1 |
CHEMBL3568 |
NA |
413 |
161 |
0.9976 |
0.9999 |
| 831 |
Nitric oxide synthase 3 |
CHEMBL4803 |
NA |
239 |
41 |
0.999 |
0.9982 |
| 832 |
Nitric oxide synthase, inducible |
CHEMBL4481 |
NA |
412 |
146 |
0.9918 |
0.9944 |
| 833 |
Nociceptin receptor |
CHEMBL2014 |
NA |
1098 |
940 |
0.9954 |
0.9968 |
| 834 |
Non-receptor tyrosine-protein kinase TYK2 |
CHEMBL3553 |
NA |
1108 |
399 |
0.9876 |
0.9906 |
| 835 |
Nuclear factor erythroid 2-related factor 2 |
CHEMBL1075094 |
NA |
299 |
109 |
0.9883 |
0.98 |
| 836 |
Nuclear receptor ROR-alpha |
CHEMBL5868 |
NA |
106 |
21 |
0.9826 |
0.9845 |
| 837 |
Nuclear receptor ROR-beta |
CHEMBL3091268 |
NA |
218 |
66 |
0.9971 |
0.9999 |
| 838 |
Nuclear receptor ROR-gamma |
CHEMBL1741186 |
NA |
2408 |
1414 |
0.9914 |
0.9949 |
| 839 |
Nuclear receptor subfamily 1 group D member 1 |
CHEMBL1961783 |
NA |
90 |
36 |
0.9937 |
1 |
| 840 |
Nuclear receptor subfamily 1 group I member 2 |
CHEMBL3401 |
NA |
402 |
88 |
0.9736 |
0.976 |
| 841 |
Nuclear receptor subfamily 1 group I member 3 |
CHEMBL5503 |
NA |
160 |
44 |
0.9954 |
0.9951 |
| 842 |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
CHEMBL3885612 |
NA |
21 |
13 |
0.9725 |
0.9047 |
| 843 |
Nuclear receptor subfamily 2 group E member 1 |
CHEMBL1961788 |
NA |
45 |
20 |
0.9697 |
0.9998 |
| 844 |
Nuclear receptor subfamily 4 group A member 2 |
CHEMBL5002 |
NA |
157 |
68 |
0.9878 |
0.9976 |
| 845 |
Nuclear receptor subfamily 4immunitygroup A member 1 |
CHEMBL1293229 |
NA |
39 |
11 |
0.992 |
0.9998 |
| 846 |
Nuclear receptor subfamily 5 group A member 2 |
CHEMBL3544 |
NA |
70 |
32 |
0.9898 |
0.9875 |
| 847 |
Nucleosome-remodeling factor subunit BPTF |
CHEMBL3085621 |
NA |
68 |
29 |
0.9542 |
0.9883 |
| 848 |
Nucleotide-binding oligomerization domain-containing protein 1 |
CHEMBL1293222 |
NA |
164 |
45 |
0.9966 |
0.9812 |
| 849 |
Nucleotide-binding oligomerization domain-containing protein 2 |
CHEMBL1293266 |
NA |
226 |
100 |
0.9914 |
0.9835 |
| 850 |
ORAI1/STIM1 |
CHEMBL3832644 |
NA |
15 |
10 |
0.9874 |
0.9879 |
| 851 |
Orexin receptor type 2 |
CHEMBL4792 |
NA |
1120 |
780 |
0.993 |
0.9952 |
| 852 |
Orexin/Hypocretin receptor type 1 |
CHEMBL5113 |
NA |
960 |
576 |
0.9891 |
0.9976 |
| 853 |
Ovarian cancer G-protein coupled receptor 1 |
CHEMBL3713916 |
NA |
10 |
10 |
1 |
1 |
| 854 |
Oxidized purine nucleoside triphosphate hydrolase |
CHEMBL3708265 |
NA |
139 |
61 |
0.994 |
0.9891 |
| 855 |
Oxoeicosanoid receptor 1 |
CHEMBL1628461 |
NA |
52 |
26 |
1 |
1 |
| 856 |
Oxysterol-binding protein 1 |
CHEMBL4523203 |
NA |
30 |
23 |
0.9998 |
0.9999 |
| 857 |
Oxysterols receptor LXR-alpha |
CHEMBL2808 |
NA |
677 |
210 |
0.9927 |
0.9964 |
| 858 |
Oxysterols receptor LXR-beta |
CHEMBL4093 |
NA |
755 |
302 |
0.9912 |
0.9947 |
| 859 |
Oxytocin receptor |
CHEMBL2049 |
NA |
572 |
424 |
0.9936 |
0.9943 |
| 860 |
P2X purinoceptor 1 |
CHEMBL2094 |
NA |
67 |
26 |
0.97 |
0.9985 |
| 861 |
P2X purinoceptor 3 |
CHEMBL2998 |
NA |
332 |
194 |
0.9687 |
0.9861 |
| 862 |
P2X purinoceptor 4 |
CHEMBL2104 |
NA |
143 |
69 |
0.9976 |
0.9857 |
| 863 |
P2X purinoceptor 7 |
CHEMBL4805 |
NA |
1072 |
827 |
0.9912 |
0.9956 |
| 864 |
P2X2/P2X3 heterotrimeric receptor |
CHEMBL3831281 |
NA |
29 |
12 |
0.9496 |
0.9679 |
| 865 |
P2Y purinoceptor 1 |
CHEMBL4315 |
NA |
371 |
238 |
0.9933 |
0.9956 |
| 866 |
P2Y purinoceptor 12 |
CHEMBL2001 |
NA |
961 |
785 |
0.9968 |
0.9986 |
| 867 |
P2Y purinoceptor 14 |
CHEMBL4518 |
NA |
288 |
199 |
0.9956 |
0.9989 |
| 868 |
P2Y purinoceptor 2 |
CHEMBL4398 |
NA |
144 |
73 |
0.9964 |
0.9999 |
| 869 |
P2Y purinoceptor 4 |
CHEMBL2123 |
NA |
91 |
32 |
0.9995 |
0.9999 |
| 870 |
P2Y purinoceptor 6 |
CHEMBL4714 |
NA |
144 |
71 |
0.9986 |
0.9998 |
| 871 |
PCSK9/LDLR |
CHEMBL4523996 |
NA |
35 |
10 |
0.9917 |
0.9459 |
| 872 |
PI3-kinase p110-alpha/p85-alpha |
CHEMBL2111367 |
H1047R |
697 |
10 |
0.9917 |
0.9653 |
| 873 |
PI3-kinase p110-alpha/p85-alpha |
CHEMBL2111367 |
NA |
697 |
567 |
0.9917 |
0.9917 |
| 874 |
PI3-kinase p110-delta/p85-alpha |
CHEMBL2111432 |
NA |
773 |
730 |
0.9929 |
0.9955 |
| 875 |
PI3-kinase subunit gamma/Phosphoinositide 3-kinase regulatory subunit 5 |
CHEMBL3430881 |
NA |
10 |
10 |
0.9622 |
0.9576 |
| 876 |
PI3K p110 beta/p85 alpha |
CHEMBL3038510 |
NA |
325 |
264 |
0.9942 |
0.9944 |
| 877 |
PRMT5/MEP50 complex |
CHEMBL3137261 |
NA |
233 |
135 |
0.9764 |
0.9813 |
| 878 |
Palmitoleoyl-protein carboxylesterase NOTUM |
CHEMBL3714531 |
C330S |
444 |
117 |
0.9977 |
0.9972 |
| 879 |
Palmitoleoyl-protein carboxylesterase NOTUM |
CHEMBL3714531 |
NA |
444 |
140 |
0.9977 |
0.9994 |
| 880 |
Pantetheinase |
CHEMBL4739843 |
NA |
32 |
13 |
1 |
1 |
| 881 |
Pantothenate kinase 3 |
CHEMBL3407328 |
NA |
83 |
26 |
0.9866 |
1 |
| 882 |
Parathyroid hormone/parathyroid hormone-related peptide receptor |
CHEMBL1793 |
NA |
79 |
44 |
1 |
1 |
| 883 |
Parkinson disease protein 7 |
CHEMBL5169188 |
NA |
24 |
14 |
0.9148 |
0.9008 |
| 884 |
Peptide deformylase, mitochondrial |
CHEMBL4647 |
NA |
45 |
32 |
1 |
1 |
| 885 |
Peptidyl-prolyl cis-trans isomerase A |
CHEMBL1949 |
NA |
134 |
31 |
0.9965 |
0.9846 |
| 886 |
Peptidyl-prolyl cis-trans isomerase FKBP1A |
CHEMBL1902 |
NA |
306 |
50 |
0.9917 |
1 |
| 887 |
Peptidyl-prolyl cis-trans isomerase FKBP1B |
CHEMBL2430 |
NA |
30 |
29 |
0.9928 |
0.9995 |
| 888 |
Peptidyl-prolyl cis-trans isomerase FKBP5 |
CHEMBL2052031 |
NA |
180 |
39 |
0.9899 |
0.9929 |
| 889 |
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
CHEMBL2288 |
NA |
372 |
51 |
0.9869 |
0.9852 |
| 890 |
Peregrin |
CHEMBL3132741 |
NA |
204 |
63 |
0.9772 |
0.996 |
| 891 |
Perforin-1 |
CHEMBL5480 |
NA |
163 |
82 |
1 |
1 |
| 892 |
Period circadian protein homolog 2 |
CHEMBL3751648 |
NA |
38 |
31 |
1 |
1 |
| 893 |
Peroxisome proliferator-activated receptor alpha |
CHEMBL239 |
NA |
1996 |
909 |
0.993 |
0.9969 |
| 894 |
Peroxisome proliferator-activated receptor delta |
CHEMBL3979 |
NA |
1357 |
649 |
0.995 |
0.997 |
| 895 |
Peroxisome proliferator-activated receptor gamma |
CHEMBL235 |
NA |
2821 |
1129 |
0.984 |
0.9929 |
| 896 |
Phenylethanolamine N-methyltransferase |
CHEMBL4617 |
NA |
140 |
32 |
0.9994 |
1 |
| 897 |
Phosphatidylcholine:ceramide cholinephosphotransferase 2 |
CHEMBL3112379 |
NA |
105 |
25 |
0.9933 |
1 |
| 898 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 |
CHEMBL1075165 |
NA |
174 |
64 |
0.9517 |
0.9837 |
| 899 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
CHEMBL4005 |
H1047R |
3027 |
25 |
0.9832 |
0.9987 |
| 900 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
CHEMBL4005 |
NA |
3027 |
507 |
0.9832 |
0.9877 |
| 901 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
CHEMBL3145 |
NA |
1326 |
371 |
0.9829 |
0.9904 |
| 902 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
CHEMBL3130 |
NA |
2459 |
702 |
0.9872 |
0.9961 |
| 903 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
CHEMBL3267 |
NA |
2045 |
474 |
0.9821 |
0.9932 |
| 904 |
Phosphatidylinositol 4-kinase beta |
CHEMBL3268 |
NA |
235 |
62 |
0.9771 |
0.9832 |
| 905 |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
CHEMBL5554 |
NA |
65 |
20 |
0.9628 |
0.9439 |
| 906 |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
CHEMBL1908383 |
NA |
83 |
31 |
0.9858 |
0.984 |
| 907 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
CHEMBL1795194 |
NA |
178 |
73 |
0.978 |
0.9999 |
| 908 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
CHEMBL1770034 |
NA |
80 |
12 |
0.9937 |
0.9791 |
| 909 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
CHEMBL1770034 |
UNDEFINED MUTATION |
80 |
35 |
0.9937 |
1 |
| 910 |
Phospholipase A and acyltransferase 2 |
CHEMBL4630860 |
NA |
33 |
10 |
1 |
1 |
| 911 |
Phospholipase A and acyltransferase 3 |
CHEMBL3831244 |
NA |
33 |
16 |
1 |
1 |
| 912 |
Phospholipase A and acyltransferase 4 |
CHEMBL4630864 |
NA |
35 |
10 |
1 |
1 |
| 913 |
Phospholipase A and acyltransferase 5 |
CHEMBL4630850 |
NA |
35 |
28 |
1 |
1 |
| 914 |
Phospholipase D1 |
CHEMBL2536 |
NA |
148 |
105 |
0.9944 |
0.9999 |
| 915 |
Phospholipase D2 |
CHEMBL2734 |
NA |
120 |
82 |
0.9937 |
0.9948 |
| 916 |
Plasma kallikrein |
CHEMBL2000 |
NA |
440 |
100 |
0.98 |
0.9906 |
| 917 |
Platelet-activating factor acetylhydrolase |
CHEMBL3514 |
NA |
194 |
58 |
0.9965 |
0.9995 |
| 918 |
Platelet-activating factor receptor |
CHEMBL250 |
NA |
62 |
44 |
0.9702 |
0.9895 |
| 919 |
Platelet-derived growth factor receptor |
CHEMBL2095189 |
NA |
114 |
85 |
0.9845 |
0.9881 |
| 920 |
Platelet-derived growth factor receptor alpha |
CHEMBL2007 |
V561D |
431 |
37 |
0.9711 |
0.9848 |
| 921 |
Platelet-derived growth factor receptor alpha |
CHEMBL2007 |
NA |
431 |
63 |
0.9711 |
0.958 |
| 922 |
Platelet-derived growth factor receptor beta |
CHEMBL1913 |
NA |
656 |
164 |
0.9747 |
0.9811 |
| 923 |
Poly [ADP-ribose] polymerase 1 |
CHEMBL3105 |
NA |
2152 |
621 |
0.9907 |
0.9951 |
| 924 |
Poly [ADP-ribose] polymerase 2 |
CHEMBL5366 |
NA |
457 |
107 |
0.9919 |
0.9955 |
| 925 |
Poly [ADP-ribose] polymerase tankyrase-1 |
CHEMBL6164 |
NA |
483 |
185 |
0.9897 |
0.9846 |
| 926 |
Poly [ADP-ribose] polymerase tankyrase-2 |
CHEMBL6154 |
NA |
512 |
188 |
0.9889 |
0.9922 |
| 927 |
Poly(ADP-ribose) glycohydrolase |
CHEMBL1795143 |
NA |
110 |
27 |
1 |
1 |
| 928 |
Polyamine deacetylase HDAC10 |
CHEMBL5103 |
NA |
311 |
53 |
0.991 |
0.9977 |
| 929 |
Polycomb protein EED |
CHEMBL2189117 |
NA |
318 |
110 |
0.9887 |
0.9812 |
| 930 |
Polyunsaturated fatty acid 5-lipoxygenase |
CHEMBL215 |
NA |
1405 |
515 |
0.9753 |
0.991 |
| 931 |
Polyunsaturated fatty acid lipoxygenase ALOX12 |
CHEMBL3687 |
NA |
114 |
28 |
0.9816 |
0.9947 |
| 932 |
Polyunsaturated fatty acid lipoxygenase ALOX15 |
CHEMBL2903 |
NA |
296 |
71 |
0.9728 |
0.9756 |
| 933 |
Potassium channel subfamily K member 13 |
CHEMBL4523461 |
NA |
17 |
14 |
1 |
1 |
| 934 |
Potassium channel subfamily K member 3 |
CHEMBL2321613 |
NA |
71 |
56 |
0.9701 |
0.9919 |
| 935 |
Potassium channel subfamily K member 9 |
CHEMBL2321614 |
NA |
54 |
19 |
0.8926 |
0.9064 |
| 936 |
Potassium channel subfamily T member 1 |
CHEMBL4739688 |
NA |
56 |
15 |
0.9532 |
0.9819 |
| 937 |
Potassium voltage-gated channel subfamily A member 3 |
CHEMBL4633 |
NA |
152 |
103 |
0.9952 |
0.9988 |
| 938 |
Potassium voltage-gated channel subfamily A member 5 |
CHEMBL4306 |
NA |
521 |
288 |
0.9956 |
0.9957 |
| 939 |
Potassium voltage-gated channel subfamily B member 1 |
CHEMBL2363000 |
NA |
26 |
21 |
0.9996 |
0.9997 |
| 940 |
Potassium voltage-gated channel subfamily KQT member 1 |
CHEMBL1866 |
NA |
33 |
10 |
0.9522 |
1 |
| 941 |
Potassium voltage-gated channel subfamily KQT member 2 |
CHEMBL2476 |
NA |
37 |
22 |
0.9845 |
0.9999 |
| 942 |
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 |
CHEMBL1795171 |
NA |
25 |
13 |
1 |
1 |
| 943 |
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 |
CHEMBL1250417 |
NA |
28 |
15 |
1 |
0.9981 |
| 944 |
Presenilin-1 |
CHEMBL2473 |
NA |
32 |
17 |
0.9792 |
0.9564 |
| 945 |
Probable G-protein coupled receptor 132 |
CHEMBL3085618 |
NA |
27 |
11 |
0.9981 |
0.9716 |
| 946 |
Probable G-protein coupled receptor 139 |
CHEMBL3632455 |
NA |
115 |
111 |
0.9995 |
0.9997 |
| 947 |
Probable G-protein coupled receptor 142 |
CHEMBL2069161 |
NA |
167 |
136 |
0.9999 |
1 |
| 948 |
Probable G-protein coupled receptor 174 |
CHEMBL3562167 |
NA |
13 |
10 |
1 |
1 |
| 949 |
Probable G-protein coupled receptor 27 |
CHEMBL4523923 |
NA |
43 |
25 |
0.9999 |
1 |
| 950 |
Probable G-protein coupled receptor 34 |
CHEMBL3562165 |
NA |
26 |
17 |
0.9998 |
0.9999 |
| 951 |
Probable global transcription activator SNF2L2 |
CHEMBL2362979 |
NA |
56 |
14 |
0.948 |
0.935 |
| 952 |
Procathepsin L |
CHEMBL3837 |
NA |
1344 |
103 |
0.9877 |
0.9977 |
| 953 |
Progesterone receptor |
CHEMBL208 |
NA |
1150 |
668 |
0.995 |
0.9977 |
| 954 |
Programmed cell death 1 ligand 1 |
CHEMBL3580522 |
NA |
105 |
17 |
0.968 |
0.9802 |
| 955 |
Programmed cell death protein 1/Programmed cell death 1 ligand 1 |
CHEMBL4523993 |
NA |
1032 |
861 |
0.9959 |
0.9987 |
| 956 |
Prokineticin receptor 1 |
CHEMBL5649 |
NA |
26 |
15 |
0.9979 |
0.9979 |
| 957 |
Prolyl endopeptidase |
CHEMBL3202 |
NA |
291 |
75 |
0.9925 |
0.9999 |
| 958 |
Prolyl endopeptidase FAP |
CHEMBL4683 |
NA |
292 |
59 |
0.9994 |
1 |
| 959 |
Prolyl hydroxylase EGLN2 |
CHEMBL3028 |
NA |
84 |
61 |
0.9962 |
0.9969 |
| 960 |
Prolyl hydroxylase EGLN3 |
CHEMBL5705 |
NA |
59 |
49 |
0.9932 |
0.9963 |
| 961 |
Proprotein convertase subtilisin/kexin type 6 |
CHEMBL2951 |
NA |
50 |
42 |
1 |
1 |
| 962 |
Proprotein convertase subtilisin/kexin type 9 |
CHEMBL2929 |
NA |
98 |
47 |
0.9793 |
0.9789 |
| 963 |
Prostacyclin receptor |
CHEMBL1995 |
NA |
191 |
113 |
0.996 |
0.9997 |
| 964 |
Prostaglandin D2 receptor |
CHEMBL4427 |
NA |
327 |
238 |
0.9966 |
0.9967 |
| 965 |
Prostaglandin D2 receptor 2 |
CHEMBL5071 |
NA |
1325 |
1053 |
0.9991 |
0.9995 |
| 966 |
Prostaglandin E synthase |
CHEMBL5658 |
NA |
913 |
498 |
0.9864 |
0.9895 |
| 967 |
Prostaglandin E2 receptor EP1 subtype |
CHEMBL1811 |
NA |
592 |
437 |
0.999 |
0.9997 |
| 968 |
Prostaglandin E2 receptor EP2 subtype |
CHEMBL1881 |
NA |
266 |
130 |
0.9943 |
0.9954 |
| 969 |
Prostaglandin E2 receptor EP3 subtype |
CHEMBL3710 |
NA |
618 |
233 |
0.9955 |
0.9977 |
| 970 |
Prostaglandin E2 receptor EP4 subtype |
CHEMBL1836 |
NA |
524 |
368 |
0.9964 |
0.9991 |
| 971 |
Prostaglandin F2-alpha receptor |
CHEMBL1987 |
NA |
73 |
51 |
0.9987 |
0.9872 |
| 972 |
Prostaglandin G/H synthase 1 |
CHEMBL221 |
NA |
719 |
136 |
0.9751 |
0.9858 |
| 973 |
Prostaglandin G/H synthase 2 |
CHEMBL230 |
NA |
2406 |
163 |
0.974 |
0.9883 |
| 974 |
Proteasome Macropain subunit |
CHEMBL3492 |
NA |
201 |
71 |
0.9809 |
0.9998 |
| 975 |
Proteasome Macropain subunit MB1 |
CHEMBL4662 |
NA |
975 |
167 |
0.9902 |
0.9962 |
| 976 |
Proteasome component C5 |
CHEMBL4208 |
NA |
166 |
39 |
0.9856 |
0.9804 |
| 977 |
Proteasome subunit beta type-10 |
CHEMBL3317334 |
NA |
79 |
33 |
0.9978 |
0.9999 |
| 978 |
Proteasome subunit beta type-8 |
CHEMBL5620 |
NA |
394 |
95 |
0.9945 |
0.9982 |
| 979 |
Proteasome subunit beta type-9 |
CHEMBL1944495 |
NA |
125 |
26 |
0.9993 |
0.9989 |
| 980 |
Protein ADM2 |
CHEMBL5267 |
NA |
25 |
20 |
1 |
1 |
| 981 |
Protein AF-9 |
CHEMBL4295761 |
NA |
52 |
20 |
0.9898 |
0.974 |
| 982 |
Protein ENL |
CHEMBL4295801 |
NA |
134 |
36 |
0.9803 |
0.9983 |
| 983 |
Protein Mdm4 |
CHEMBL1255126 |
NA |
202 |
43 |
0.9795 |
0.9895 |
| 984 |
Protein O-GlcNAcase |
CHEMBL5921 |
NA |
205 |
35 |
1 |
1 |
| 985 |
Protein Wnt-3a |
CHEMBL1255137 |
NA |
51 |
27 |
0.9883 |
0.9704 |
| 986 |
Protein arginine N-methyltransferase 1 |
CHEMBL5524 |
NA |
244 |
26 |
0.9761 |
0.9597 |
| 987 |
Protein arginine N-methyltransferase 5 |
CHEMBL1795116 |
NA |
362 |
121 |
0.9858 |
0.9978 |
| 988 |
Protein arginine N-methyltransferase 6 |
CHEMBL1275221 |
NA |
158 |
61 |
0.9908 |
0.9995 |
| 989 |
Protein arginine N-methyltransferase 8 |
CHEMBL3108648 |
NA |
61 |
20 |
0.9931 |
1 |
| 990 |
Protein cereblon |
CHEMBL3763008 |
NA |
207 |
50 |
0.9955 |
0.9997 |
| 991 |
Protein cereblon-IKZF2 |
CHEMBL5465554 |
NA |
10 |
10 |
1 |
1 |
| 992 |
Protein cereblon/Aiolos |
CHEMBL4296167 |
NA |
34 |
34 |
1 |
1 |
| 993 |
Protein cereblon/Bromodomain-containing protein 4 |
CHEMBL4296138 |
NA |
10 |
10 |
1 |
1 |
| 994 |
Protein cereblon/Cyclin-dependent kinase 12 |
CHEMBL4879535 |
NA |
10 |
10 |
1 |
1 |
| 995 |
Protein cereblon/DNA damage-binding protein 1 |
CHEMBL4630734 |
NA |
100 |
64 |
0.9998 |
0.9998 |
| 996 |
Protein cereblon/Estrogen receptor |
CHEMBL4523681 |
NA |
15 |
15 |
0.9993 |
0.9991 |
| 997 |
Protein cereblon/GSPT1 |
CHEMBL4296168 |
NA |
17 |
14 |
1 |
1 |
| 998 |
Protein cereblon/IRAK4 |
CHEMBL4523710 |
NA |
11 |
11 |
0.9889 |
0.9892 |
| 999 |
Protein cereblon/Serine/threonine-protein kinase WEE1 |
CHEMBL4630732 |
NA |
12 |
10 |
1 |
1 |
| 1000 |
Protein cereblon/Tyrosine-protein kinase BTK |
CHEMBL4523704 |
NA |
17 |
15 |
0.9998 |
0.9997 |
| 1001 |
Protein cereblon/Tyrosine-protein kinase ITK/TSK |
CHEMBL5465213 |
NA |
10 |
10 |
1 |
1 |
| 1002 |
Protein disulfide-isomerase |
CHEMBL5422 |
NA |
159 |
83 |
0.9824 |
0.9961 |
| 1003 |
Protein farnesyltransferase |
CHEMBL2094108 |
NA |
609 |
387 |
0.984 |
0.9872 |
| 1004 |
Protein kinase C alpha type |
CHEMBL299 |
NA |
407 |
75 |
0.9811 |
0.9864 |
| 1005 |
Protein kinase C beta type |
CHEMBL3045 |
NA |
178 |
16 |
0.9474 |
0.9495 |
| 1006 |
Protein kinase C delta type |
CHEMBL2996 |
NA |
293 |
29 |
0.9834 |
0.9761 |
| 1007 |
Protein kinase C epsilon type |
CHEMBL3582 |
NA |
197 |
63 |
0.9665 |
0.9862 |
| 1008 |
Protein kinase C iota type |
CHEMBL2598 |
NA |
75 |
28 |
0.9734 |
0.9768 |
| 1009 |
Protein kinase C theta type |
CHEMBL3920 |
NA |
462 |
134 |
0.9823 |
0.997 |
| 1010 |
Protein kinase C zeta type |
CHEMBL3438 |
NA |
157 |
15 |
0.9928 |
0.9251 |
| 1011 |
Protein mono-ADP-ribosyltransferase PARP10 |
CHEMBL2429708 |
NA |
150 |
23 |
0.9929 |
0.9689 |
| 1012 |
Protein mono-ADP-ribosyltransferase PARP11 |
CHEMBL2380189 |
NA |
39 |
18 |
0.9914 |
0.941 |
| 1013 |
Protein mono-ADP-ribosyltransferase PARP14 |
CHEMBL2176777 |
NA |
131 |
21 |
0.9771 |
0.9995 |
| 1014 |
Protein mono-ADP-ribosyltransferase PARP15 |
CHEMBL2176778 |
NA |
70 |
13 |
0.9804 |
0.9995 |
| 1015 |
Protein mono-ADP-ribosyltransferase TIPARP |
CHEMBL2380188 |
NA |
84 |
13 |
0.9912 |
0.969 |
| 1016 |
Protein polybromo-1 |
CHEMBL1795184 |
NA |
92 |
31 |
0.9651 |
0.9787 |
| 1017 |
Protein smoothened |
CHEMBL5971 |
V404M |
232 |
10 |
0.9742 |
0.7876 |
| 1018 |
Protein smoothened |
CHEMBL5971 |
D473H |
232 |
14 |
0.9742 |
0.8429 |
| 1019 |
Protein smoothened |
CHEMBL5971 |
NA |
232 |
176 |
0.9742 |
0.9877 |
| 1020 |
Protein-S-isoprenylcysteine O-methyltransferase |
CHEMBL4699 |
NA |
109 |
14 |
0.9898 |
0.9995 |
| 1021 |
Protein-arginine deiminase type-4 |
CHEMBL6111 |
NA |
96 |
13 |
0.9915 |
1 |
| 1022 |
Protein-glutamine gamma-glutamyltransferase |
CHEMBL2730 |
NA |
350 |
28 |
0.9867 |
0.9693 |
| 1023 |
Protein-lysine 6-oxidase |
CHEMBL2249 |
NA |
52 |
20 |
0.9859 |
0.9819 |
| 1024 |
Protein-serine O-palmitoleoyltransferase porcupine |
CHEMBL1255163 |
NA |
58 |
55 |
0.9999 |
0.9995 |
| 1025 |
Protein-tyrosine kinase 2-beta |
CHEMBL5469 |
NA |
94 |
27 |
0.9513 |
0.9465 |
| 1026 |
Protein-tyrosine kinase 6 |
CHEMBL4601 |
NA |
100 |
17 |
0.9409 |
0.9136 |
| 1027 |
Proteinase-activated receptor 1 |
CHEMBL3974 |
NA |
462 |
259 |
0.9974 |
0.9991 |
| 1028 |
Proteinase-activated receptor 2 |
CHEMBL5963 |
NA |
85 |
42 |
0.9834 |
0.9859 |
| 1029 |
Proteinase-activated receptor 4 |
CHEMBL4691 |
NA |
171 |
148 |
0.9963 |
0.9995 |
| 1030 |
Prothrombin |
CHEMBL204 |
NA |
1703 |
43 |
0.9881 |
0.9566 |
| 1031 |
Proto-oncogene Wnt-3 |
CHEMBL6079 |
NA |
29 |
29 |
1 |
1 |
| 1032 |
Proto-oncogene tyrosine-protein kinase ROS |
CHEMBL5568 |
NA |
159 |
49 |
0.9714 |
0.9455 |
| 1033 |
Proto-oncogene tyrosine-protein kinase Src |
CHEMBL267 |
NA |
1185 |
167 |
0.9612 |
0.9694 |
| 1034 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
V804M |
592 |
20 |
0.9735 |
0.9201 |
| 1035 |
Proto-oncogene tyrosine-protein kinase receptor Ret |
CHEMBL2041 |
NA |
592 |
168 |
0.9735 |
0.9676 |
| 1036 |
Proton-coupled folate transporter |
CHEMBL1795188 |
NA |
37 |
34 |
0.9999 |
0.9999 |
| 1037 |
Purine nucleoside phosphorylase |
CHEMBL4338 |
H257G |
163 |
10 |
0.9927 |
1 |
| 1038 |
Purine nucleoside phosphorylase |
CHEMBL4338 |
NA |
163 |
40 |
0.9927 |
1 |
| 1039 |
Putative P2Y purinoceptor 10 |
CHEMBL3562166 |
NA |
32 |
27 |
1 |
1 |
| 1040 |
Pyroglutamylated RF-amide peptide receptor |
CHEMBL5852 |
NA |
86 |
41 |
0.9915 |
0.9873 |
| 1041 |
Pyruvate kinase PKM |
CHEMBL1075189 |
NA |
187 |
28 |
0.9693 |
0.8875 |
| 1042 |
RAC-alpha serine/threonine-protein kinase |
CHEMBL4282 |
NA |
1012 |
372 |
0.9763 |
0.9939 |
| 1043 |
RAC-beta serine/threonine-protein kinase |
CHEMBL2431 |
NA |
286 |
78 |
0.9909 |
0.9896 |
| 1044 |
RAC-gamma serine/threonine-protein kinase |
CHEMBL4816 |
NA |
217 |
77 |
0.9807 |
0.9888 |
| 1045 |
RAF proto-oncogene serine/threonine-protein kinase |
CHEMBL1906 |
Y340E,Y341E |
430 |
12 |
0.9796 |
1 |
| 1046 |
RAF proto-oncogene serine/threonine-protein kinase |
CHEMBL1906 |
NA |
430 |
49 |
0.9796 |
0.9764 |
| 1047 |
RNA demethylase ALKBH5 |
CHEMBL3621037 |
NA |
72 |
24 |
0.9581 |
0.9804 |
| 1048 |
RXR alpha/PPAR gamma |
CHEMBL2111394 |
NA |
15 |
14 |
0.9353 |
0.9347 |
| 1049 |
Ras guanyl-releasing protein 3 |
CHEMBL3638 |
NA |
41 |
37 |
0.9993 |
0.9991 |
| 1050 |
Receptor tyrosine-protein kinase erbB-2 |
CHEMBL1824 |
NA |
1086 |
468 |
0.981 |
0.9907 |
| 1051 |
Receptor tyrosine-protein kinase erbB-3 |
CHEMBL5838 |
L858R |
52 |
23 |
0.9948 |
0.9974 |
| 1052 |
Receptor tyrosine-protein kinase erbB-4 |
CHEMBL3009 |
NA |
196 |
104 |
0.981 |
0.9789 |
| 1053 |
Receptor-interacting serine/threonine-protein kinase 1 |
CHEMBL5464 |
NA |
535 |
227 |
0.985 |
0.9952 |
| 1054 |
Receptor-interacting serine/threonine-protein kinase 2 |
CHEMBL5014 |
NA |
335 |
145 |
0.9749 |
0.9888 |
| 1055 |
Receptor-interacting serine/threonine-protein kinase 3 |
CHEMBL1795199 |
NA |
94 |
44 |
0.9505 |
0.9394 |
| 1056 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
D835H |
2201 |
10 |
0.9752 |
0.9139 |
| 1057 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
D835Y |
2201 |
163 |
0.9752 |
0.9859 |
| 1058 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
UNDEFINED MUTATION |
2201 |
208 |
0.9752 |
0.9776 |
| 1059 |
Receptor-type tyrosine-protein kinase FLT3 |
CHEMBL1974 |
NA |
2201 |
443 |
0.9752 |
0.9884 |
| 1060 |
Receptor-type tyrosine-protein phosphatase C |
CHEMBL3243 |
NA |
47 |
10 |
0.9821 |
0.9888 |
| 1061 |
Receptor-type tyrosine-protein phosphatase alpha |
CHEMBL3918 |
NA |
24 |
10 |
0.9379 |
0.9989 |
| 1062 |
Reduced folate transporter |
CHEMBL4833 |
NA |
25 |
24 |
0.9999 |
0.9999 |
| 1063 |
Relaxin receptor 1 |
CHEMBL1293316 |
NA |
113 |
68 |
0.9985 |
0.9992 |
| 1064 |
Relaxin-3 receptor 1 |
CHEMBL1628472 |
NA |
63 |
30 |
1 |
1 |
| 1065 |
Relaxin-3 receptor 2 |
CHEMBL1628473 |
NA |
10 |
10 |
1 |
1 |
| 1066 |
Renin |
CHEMBL286 |
NA |
1287 |
313 |
0.9984 |
0.9997 |
| 1067 |
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
CHEMBL3860 |
NA |
147 |
24 |
0.993 |
0.986 |
| 1068 |
Retinaldehyde dehydrogenase 3 |
CHEMBL3579 |
NA |
99 |
12 |
0.9916 |
0.9431 |
| 1069 |
Retinoblastoma-associated protein |
CHEMBL5288 |
NA |
20 |
12 |
0.9925 |
0.9875 |
| 1070 |
Retinoic acid receptor RXR-alpha |
CHEMBL2061 |
NA |
454 |
173 |
0.9923 |
0.9995 |
| 1071 |
Retinoic acid receptor RXR-alpha/gamma |
CHEMBL3885633 |
NA |
11 |
11 |
1 |
1 |
| 1072 |
Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-alpha |
CHEMBL3430879 |
NA |
41 |
34 |
0.9959 |
0.9946 |
| 1073 |
Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-beta |
CHEMBL3430878 |
NA |
53 |
49 |
0.9986 |
0.9992 |
| 1074 |
Retinoic acid receptor RXR-beta |
CHEMBL1870 |
NA |
216 |
122 |
0.9958 |
0.9997 |
| 1075 |
Retinoic acid receptor RXR-gamma |
CHEMBL2004 |
NA |
183 |
100 |
0.9957 |
0.9988 |
| 1076 |
Retinoic acid receptor alpha |
CHEMBL2055 |
NA |
95 |
41 |
0.9997 |
0.9994 |
| 1077 |
Retinoic acid receptor beta |
CHEMBL2008 |
NA |
115 |
76 |
0.9997 |
0.9996 |
| 1078 |
Retinoic acid receptor gamma |
CHEMBL2003 |
NA |
137 |
70 |
0.9997 |
0.9995 |
| 1079 |
Retinol-binding protein 4 |
CHEMBL3100 |
NA |
160 |
43 |
0.9999 |
1 |
| 1080 |
Rho-associated protein kinase 1 |
CHEMBL3231 |
NA |
568 |
109 |
0.9838 |
0.9935 |
| 1081 |
Rho-associated protein kinase 2 |
CHEMBL2973 |
NA |
907 |
236 |
0.9866 |
0.9972 |
| 1082 |
Ribosomal protein S6 kinase alpha-3 |
CHEMBL2345 |
NA |
160 |
43 |
0.9593 |
0.983 |
| 1083 |
Ribosomal protein S6 kinase alpha-5 |
CHEMBL4237 |
NA |
87 |
13 |
0.9565 |
0.9991 |
| 1084 |
Ribosomal protein S6 kinase beta-1 |
CHEMBL4501 |
NA |
118 |
18 |
0.9577 |
0.9201 |
| 1085 |
Ribosomal protein S6 kinase beta-1 |
CHEMBL4501 |
D18H,T412E |
118 |
22 |
0.9577 |
1 |
| 1086 |
Ribosomal protein S6 kinase beta-1 |
CHEMBL4501 |
T412E |
118 |
34 |
0.9577 |
1 |
| 1087 |
Ribosyldihydronicotinamide dehydrogenase [quinone] |
CHEMBL3959 |
NA |
231 |
51 |
0.9905 |
0.9883 |
| 1088 |
S-adenosylmethionine synthase isoform type-2 |
CHEMBL3313835 |
NA |
235 |
130 |
0.9986 |
0.9987 |
| 1089 |
S-methyl-5'-thioadenosine phosphorylase |
CHEMBL4941 |
NA |
55 |
13 |
1 |
1 |
| 1090 |
SCN8A/SCN1B |
CHEMBL4523671 |
NA |
25 |
23 |
1 |
1 |
| 1091 |
SKP1-SKP2-CKS1 |
CHEMBL5482973 |
NA |
37 |
20 |
0.9884 |
1 |
| 1092 |
SOS1-KRAS |
CHEMBL5465393 |
NA |
126 |
13 |
0.9951 |
0.9998 |
| 1093 |
SOS1-KRAS |
CHEMBL5465393 |
G12D |
126 |
15 |
0.9951 |
1 |
| 1094 |
SOS1-KRAS |
CHEMBL5465393 |
G12C |
126 |
83 |
0.9951 |
0.9978 |
| 1095 |
SUMO-activating enzyme |
CHEMBL2095174 |
NA |
67 |
56 |
0.9985 |
1 |
| 1096 |
Scavenger receptor class B member 1 |
CHEMBL1914272 |
NA |
49 |
47 |
1 |
1 |
| 1097 |
Secreted frizzled-related protein 1 |
CHEMBL5517 |
NA |
68 |
32 |
0.9882 |
1 |
| 1098 |
Sentrin-specific protease 1 |
CHEMBL1909484 |
NA |
105 |
29 |
0.9848 |
0.9809 |
| 1099 |
Sentrin-specific protease 2 |
CHEMBL2176776 |
NA |
63 |
16 |
0.9905 |
0.9957 |
| 1100 |
Sentrin-specific protease 5 |
CHEMBL4802012 |
NA |
48 |
11 |
1 |
1 |
| 1101 |
Serine protease hepsin |
CHEMBL2079849 |
D161E,R162K |
174 |
16 |
0.9977 |
0.9992 |
| 1102 |
Serine protease hepsin |
CHEMBL2079849 |
NA |
174 |
38 |
0.9977 |
0.9987 |
| 1103 |
Serine-protein kinase ATM |
CHEMBL3797 |
NA |
427 |
166 |
0.9939 |
0.9993 |
| 1104 |
Serine/threonine-protein kinase 16 |
CHEMBL3938 |
NA |
42 |
19 |
0.9531 |
0.9865 |
| 1105 |
Serine/threonine-protein kinase 17A |
CHEMBL4525 |
NA |
96 |
21 |
0.9652 |
0.9546 |
| 1106 |
Serine/threonine-protein kinase 17B |
CHEMBL3980 |
NA |
127 |
34 |
0.9661 |
0.9667 |
| 1107 |
Serine/threonine-protein kinase 24 |
CHEMBL5082 |
NA |
49 |
28 |
0.975 |
0.9873 |
| 1108 |
Serine/threonine-protein kinase 26 |
CHEMBL5941 |
NA |
63 |
15 |
0.9666 |
0.9695 |
| 1109 |
Serine/threonine-protein kinase 3 |
CHEMBL4708 |
NA |
104 |
35 |
0.9668 |
0.9719 |
| 1110 |
Serine/threonine-protein kinase 4 |
CHEMBL4598 |
NA |
125 |
71 |
0.983 |
0.9926 |
| 1111 |
Serine/threonine-protein kinase ATR |
CHEMBL5024 |
NA |
358 |
106 |
0.9963 |
0.9972 |
| 1112 |
Serine/threonine-protein kinase B-raf |
CHEMBL5145 |
NA |
1950 |
88 |
0.9817 |
0.9851 |
| 1113 |
Serine/threonine-protein kinase B-raf |
CHEMBL5145 |
V600E |
1950 |
1039 |
0.9817 |
0.9959 |
| 1114 |
Serine/threonine-protein kinase Chk1 |
CHEMBL4630 |
NA |
1059 |
316 |
0.9931 |
0.9959 |
| 1115 |
Serine/threonine-protein kinase D1 |
CHEMBL3863 |
NA |
83 |
14 |
0.9322 |
0.9791 |
| 1116 |
Serine/threonine-protein kinase DCLK1 |
CHEMBL5683 |
NA |
41 |
31 |
0.9317 |
0.9795 |
| 1117 |
Serine/threonine-protein kinase Nek2 |
CHEMBL3835 |
NA |
123 |
38 |
0.9679 |
0.9958 |
| 1118 |
Serine/threonine-protein kinase PAK 1 |
CHEMBL4600 |
NA |
293 |
104 |
0.9872 |
0.9868 |
| 1119 |
Serine/threonine-protein kinase PAK 4 |
CHEMBL4482 |
NA |
246 |
49 |
0.9875 |
0.9673 |
| 1120 |
Serine/threonine-protein kinase PLK1 |
CHEMBL3024 |
T210D |
792 |
41 |
0.9748 |
1 |
| 1121 |
Serine/threonine-protein kinase PLK1 |
CHEMBL3024 |
NA |
792 |
131 |
0.9748 |
0.9849 |
| 1122 |
Serine/threonine-protein kinase PLK2 |
CHEMBL5938 |
NA |
138 |
75 |
0.9729 |
0.9847 |
| 1123 |
Serine/threonine-protein kinase PLK3 |
CHEMBL4897 |
NA |
104 |
44 |
0.937 |
0.9521 |
| 1124 |
Serine/threonine-protein kinase PLK4 |
CHEMBL3788 |
NA |
346 |
53 |
0.9873 |
0.9906 |
| 1125 |
Serine/threonine-protein kinase RIO2 |
CHEMBL6000 |
NA |
37 |
18 |
0.9672 |
0.9542 |
| 1126 |
Serine/threonine-protein kinase SIK1 |
CHEMBL6082 |
NA |
67 |
15 |
0.9623 |
0.7438 |
| 1127 |
Serine/threonine-protein kinase SIK2 |
CHEMBL5699 |
NA |
134 |
29 |
0.9824 |
0.9437 |
| 1128 |
Serine/threonine-protein kinase SIK3 |
CHEMBL6149 |
NA |
88 |
33 |
0.9836 |
0.9467 |
| 1129 |
Serine/threonine-protein kinase SMG1 |
CHEMBL1795195 |
NA |
23 |
19 |
0.9926 |
1 |
| 1130 |
Serine/threonine-protein kinase Sgk1 |
CHEMBL2343 |
NA |
151 |
75 |
0.9734 |
0.9996 |
| 1131 |
Serine/threonine-protein kinase TBK1 |
CHEMBL5408 |
NA |
146 |
48 |
0.9767 |
0.9808 |
| 1132 |
Serine/threonine-protein kinase TNNI3K |
CHEMBL5260 |
NA |
219 |
130 |
0.9875 |
0.9995 |
| 1133 |
Serine/threonine-protein kinase ULK1 |
CHEMBL6006 |
NA |
123 |
90 |
0.9759 |
0.9983 |
| 1134 |
Serine/threonine-protein kinase VRK1 |
CHEMBL1293199 |
NA |
31 |
30 |
0.9936 |
1 |
| 1135 |
Serine/threonine-protein kinase WNK1 |
CHEMBL1075173 |
NA |
17 |
10 |
0.9326 |
0.9999 |
| 1136 |
Serine/threonine-protein kinase haspin |
CHEMBL1075163 |
NA |
98 |
57 |
0.9654 |
0.9491 |
| 1137 |
Serine/threonine-protein kinase mTOR |
CHEMBL2842 |
NA |
1420 |
372 |
0.9883 |
0.9971 |
| 1138 |
Serine/threonine-protein kinase pim-1 |
CHEMBL2147 |
NA |
1392 |
190 |
0.986 |
0.988 |
| 1139 |
Serine/threonine-protein kinase pim-2 |
CHEMBL4523 |
NA |
795 |
60 |
0.9929 |
0.9766 |
| 1140 |
Serine/threonine-protein kinase pim-3 |
CHEMBL5407 |
NA |
474 |
75 |
0.9885 |
0.9944 |
| 1141 |
Serine/threonine-protein kinase/endoribonuclease IRE1 |
CHEMBL1163101 |
NA |
120 |
69 |
0.9846 |
0.9952 |
| 1142 |
Short transient receptor potential channel 5 |
CHEMBL1250411 |
NA |
122 |
71 |
0.9801 |
1 |
| 1143 |
Short transient receptor potential channel 6 |
CHEMBL2417347 |
NA |
33 |
23 |
0.9648 |
1 |
| 1144 |
Sialidase-1 |
CHEMBL2726 |
NA |
37 |
16 |
0.9999 |
1 |
| 1145 |
Sialidase-3 |
CHEMBL3046 |
NA |
46 |
18 |
1 |
1 |
| 1146 |
Sialidase-4 |
CHEMBL4174 |
NA |
37 |
11 |
1 |
1 |
| 1147 |
Sigma intracellular receptor 2 |
CHEMBL4105907 |
NA |
462 |
220 |
0.9733 |
0.9897 |
| 1148 |
Sigma non-opioid intracellular receptor 1 |
CHEMBL287 |
NA |
1044 |
763 |
0.9816 |
0.9931 |
| 1149 |
Signal peptide peptidase-like 2A |
CHEMBL4105833 |
NA |
33 |
28 |
0.9993 |
0.997 |
| 1150 |
Signal transducer and activator of transcription 3 |
CHEMBL4026 |
NA |
649 |
201 |
0.9757 |
0.9739 |
| 1151 |
Signal transducer and activator of transcription 6 |
CHEMBL5401 |
NA |
98 |
47 |
0.9978 |
0.9999 |
| 1152 |
Small conductance calcium-activated potassium channel protein 3 |
CHEMBL3381 |
NA |
13 |
10 |
0.9944 |
0.9959 |
| 1153 |
Sodium channel protein type 1 subunit alpha |
CHEMBL1845 |
NA |
58 |
12 |
0.9623 |
0.9172 |
| 1154 |
Sodium channel protein type 10 subunit alpha |
CHEMBL5451 |
NA |
204 |
134 |
0.9845 |
0.9933 |
| 1155 |
Sodium channel protein type 2 subunit alpha |
CHEMBL4187 |
NA |
97 |
22 |
0.9423 |
0.9005 |
| 1156 |
Sodium channel protein type 3 subunit alpha |
CHEMBL5163 |
NA |
117 |
49 |
0.959 |
0.9523 |
| 1157 |
Sodium channel protein type 4 subunit alpha |
CHEMBL2072 |
NA |
70 |
24 |
0.961 |
0.9713 |
| 1158 |
Sodium channel protein type 5 subunit alpha |
CHEMBL1980 |
NA |
562 |
246 |
0.9696 |
0.9801 |
| 1159 |
Sodium channel protein type 7 subunit alpha |
CHEMBL3585 |
NA |
77 |
44 |
0.9593 |
0.9363 |
| 1160 |
Sodium channel protein type 8 subunit alpha |
CHEMBL5202 |
NA |
52 |
25 |
0.948 |
0.8831 |
| 1161 |
Sodium channel protein type 9 subunit alpha |
CHEMBL4296 |
NA |
2436 |
943 |
0.9892 |
0.9926 |
| 1162 |
Sodium channel protein type 9 subunit alpha/beta-1/beta-2 |
CHEMBL4630765 |
NA |
33 |
30 |
0.9998 |
0.9997 |
| 1163 |
Sodium- and chloride-dependent GABA transporter 1 |
CHEMBL1903 |
NA |
59 |
33 |
0.9996 |
1 |
| 1164 |
Sodium- and chloride-dependent glycine transporter 1 |
CHEMBL2337 |
NA |
672 |
400 |
0.9964 |
0.9984 |
| 1165 |
Sodium- and chloride-dependent glycine transporter 2 |
CHEMBL3060 |
NA |
154 |
48 |
0.9974 |
0.9886 |
| 1166 |
Sodium-dependent dopamine transporter |
CHEMBL238 |
NA |
1452 |
616 |
0.9868 |
0.9962 |
| 1167 |
Sodium-dependent neutral amino acid transporter B(0)AT2 |
CHEMBL3351189 |
NA |
27 |
11 |
1 |
1 |
| 1168 |
Sodium-dependent noradrenaline transporter |
CHEMBL222 |
NA |
1750 |
910 |
0.9915 |
0.996 |
| 1169 |
Sodium-dependent phosphate transport protein 2B |
CHEMBL4295685 |
NA |
67 |
46 |
0.9929 |
0.9908 |
| 1170 |
Sodium-dependent proline transporter |
CHEMBL3317335 |
NA |
49 |
34 |
0.9999 |
1 |
| 1171 |
Sodium-dependent serotonin transporter |
CHEMBL228 |
I179C |
2911 |
15 |
0.9903 |
1 |
| 1172 |
Sodium-dependent serotonin transporter |
CHEMBL228 |
W103A |
2911 |
15 |
0.9903 |
1 |
| 1173 |
Sodium-dependent serotonin transporter |
CHEMBL228 |
NA |
2911 |
1669 |
0.9903 |
0.9944 |
| 1174 |
Sodium/glucose cotransporter 1 |
CHEMBL4979 |
NA |
395 |
179 |
0.9947 |
0.9988 |
| 1175 |
Sodium/glucose cotransporter 2 |
CHEMBL3884 |
NA |
941 |
793 |
0.9992 |
0.9999 |
| 1176 |
Sodium/hydrogen exchanger 1 |
CHEMBL2781 |
NA |
132 |
89 |
0.9979 |
1 |
| 1177 |
Sodium/hydrogen exchanger 3 |
CHEMBL3273 |
NA |
87 |
69 |
1 |
1 |
| 1178 |
Sodium/nucleoside cotransporter 2 |
CHEMBL5780 |
NA |
34 |
15 |
0.9996 |
1 |
| 1179 |
Soluble guanylate cyclase alpha1/beta1 complex |
CHEMBL3137281 |
NA |
29 |
15 |
0.9904 |
1 |
| 1180 |
Solute carrier family 2, facilitated glucose transporter member 1 |
CHEMBL2535 |
NA |
183 |
138 |
0.9779 |
0.9775 |
| 1181 |
Solute carrier family 2, facilitated glucose transporter member 2 |
CHEMBL5873 |
NA |
61 |
30 |
0.9844 |
0.9674 |
| 1182 |
Solute carrier family 2, facilitated glucose transporter member 3 |
CHEMBL5215 |
NA |
147 |
84 |
0.9934 |
0.9887 |
| 1183 |
Solute carrier family 2, facilitated glucose transporter member 4 |
CHEMBL5874 |
NA |
64 |
40 |
0.9728 |
0.9996 |
| 1184 |
Solute carrier family 22 member 1 |
CHEMBL5685 |
NA |
95 |
25 |
0.9055 |
0.8644 |
| 1185 |
Solute carrier family 22 member 12 |
CHEMBL6120 |
NA |
339 |
105 |
0.9952 |
0.9994 |
| 1186 |
Solute carrier family 22 member 2 |
CHEMBL1743122 |
NA |
47 |
20 |
0.8234 |
0.7696 |
| 1187 |
Somatostatin receptor type 1 |
CHEMBL1917 |
NA |
137 |
20 |
0.9911 |
0.9749 |
| 1188 |
Somatostatin receptor type 2 |
CHEMBL1804 |
NA |
280 |
177 |
0.992 |
0.9991 |
| 1189 |
Somatostatin receptor type 3 |
CHEMBL2028 |
NA |
311 |
134 |
0.9978 |
0.9946 |
| 1190 |
Somatostatin receptor type 4 |
CHEMBL1853 |
NA |
194 |
96 |
0.9932 |
0.9853 |
| 1191 |
Somatostatin receptor type 5 |
CHEMBL1792 |
NA |
360 |
237 |
0.9963 |
0.9956 |
| 1192 |
Son of sevenless homolog 1 |
CHEMBL2079846 |
NA |
265 |
88 |
0.9964 |
0.9999 |
| 1193 |
Sortilin/Progranulin |
CHEMBL4680051 |
NA |
30 |
15 |
1 |
1 |
| 1194 |
Sphingomyelin phosphodiesterase |
CHEMBL2760 |
NA |
125 |
10 |
0.9688 |
0.9835 |
| 1195 |
Sphingomyelin phosphodiesterase 3 |
CHEMBL4523470 |
NA |
123 |
71 |
0.9961 |
1 |
| 1196 |
Sphingosine 1-phosphate receptor 1 |
CHEMBL4333 |
NA |
1526 |
1293 |
0.995 |
0.9959 |
| 1197 |
Sphingosine 1-phosphate receptor 2 |
CHEMBL2955 |
NA |
238 |
113 |
0.9977 |
0.9999 |
| 1198 |
Sphingosine 1-phosphate receptor 3 |
CHEMBL3892 |
NA |
684 |
328 |
0.9956 |
0.9959 |
| 1199 |
Sphingosine 1-phosphate receptor 4 |
CHEMBL3230 |
NA |
287 |
173 |
0.9973 |
0.9987 |
| 1200 |
Sphingosine 1-phosphate receptor 5 |
CHEMBL2274 |
NA |
319 |
245 |
0.9964 |
0.9971 |
| 1201 |
Sphingosine kinase 1 |
CHEMBL4394 |
NA |
212 |
54 |
0.9804 |
0.9986 |
| 1202 |
Sphingosine kinase 2 |
CHEMBL3023 |
NA |
180 |
46 |
0.9961 |
0.9978 |
| 1203 |
Spindlin-1 |
CHEMBL4523509 |
NA |
38 |
23 |
0.9992 |
1 |
| 1204 |
Splicing factor 3B subunit 3 |
CHEMBL1250378 |
NA |
15 |
10 |
0.9399 |
0.9858 |
| 1205 |
Squalene synthase |
CHEMBL3338 |
NA |
26 |
16 |
0.9965 |
0.9944 |
| 1206 |
Stearoyl-CoA desaturase |
CHEMBL5555 |
NA |
503 |
380 |
0.9985 |
0.9995 |
| 1207 |
Steroid 17-alpha-hydroxylase/17,20 lyase |
CHEMBL3522 |
NA |
302 |
192 |
0.9994 |
0.9993 |
| 1208 |
Steroid 21-hydroxylase |
CHEMBL2759 |
NA |
13 |
11 |
1 |
1 |
| 1209 |
Steroid hormone receptor ERR1 |
CHEMBL3429 |
NA |
128 |
31 |
0.9964 |
0.95 |
| 1210 |
Steroidogenic factor 1 |
CHEMBL4666 |
NA |
44 |
28 |
0.9719 |
0.9674 |
| 1211 |
Sterol O-acyltransferase 1 |
CHEMBL2782 |
NA |
212 |
78 |
0.9878 |
0.9995 |
| 1212 |
Sterol O-acyltransferase 2 |
CHEMBL4465 |
NA |
128 |
54 |
0.9783 |
0.9961 |
| 1213 |
Sterol regulatory element-binding protein 1 |
CHEMBL4630818 |
NA |
28 |
10 |
0.999 |
0.8371 |
| 1214 |
Steryl-sulfatase |
CHEMBL3559 |
NA |
321 |
190 |
0.998 |
0.9934 |
| 1215 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
R293Q |
440 |
25 |
0.9921 |
0.9999 |
| 1216 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
UNDEFINED MUTATION |
440 |
27 |
0.9921 |
0.9074 |
| 1217 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
G230A,R293Q |
440 |
50 |
0.9921 |
0.9998 |
| 1218 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
R71H,G230A,R293Q |
440 |
60 |
0.9921 |
0.9994 |
| 1219 |
Stimulator of interferon genes protein |
CHEMBL4523377 |
NA |
440 |
175 |
0.9921 |
0.9899 |
| 1220 |
Stromal cell-derived factor 1 |
CHEMBL3286074 |
NA |
34 |
26 |
0.9471 |
0.9787 |
| 1221 |
Stromelysin-1 |
CHEMBL283 |
NA |
613 |
13 |
0.9806 |
0.829 |
| 1222 |
Substance-K receptor |
CHEMBL2327 |
NA |
357 |
152 |
0.9744 |
0.9983 |
| 1223 |
Substance-P receptor |
CHEMBL249 |
NA |
844 |
723 |
0.9931 |
0.9996 |
| 1224 |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
CHEMBL4105824 |
NA |
35 |
16 |
0.9864 |
1 |
| 1225 |
Succinate receptor 1 |
CHEMBL2150838 |
NA |
94 |
72 |
0.9993 |
1 |
| 1226 |
Sulfonylurea receptor 1, Kir6.2 |
CHEMBL2096972 |
NA |
55 |
33 |
0.9586 |
0.996 |
| 1227 |
Sulfonylurea receptor 2, Kir6.2 |
CHEMBL2095198 |
NA |
72 |
43 |
0.9827 |
0.975 |
| 1228 |
Suppressor of tumorigenicity 14 protein |
CHEMBL3018 |
NA |
340 |
88 |
0.9932 |
0.9998 |
| 1229 |
Survival motor neuron protein |
CHEMBL1293232 |
NA |
38 |
17 |
0.9999 |
0.9999 |
| 1230 |
Synaptic vesicular amine transporter |
CHEMBL1893 |
NA |
22 |
10 |
0.8705 |
0.9994 |
| 1231 |
Syntenin-1/Syndecan-2 |
CHEMBL4888448 |
NA |
29 |
13 |
1 |
0.9989 |
| 1232 |
T-cell surface glycoprotein CD4 |
CHEMBL2754 |
NA |
16 |
10 |
0.9408 |
1 |
| 1233 |
TAK1/TAB1 |
CHEMBL3038499 |
NA |
110 |
50 |
0.9791 |
0.9571 |
| 1234 |
TEL/KDR |
CHEMBL4630759 |
NA |
20 |
14 |
0.9937 |
0.9876 |
| 1235 |
TGF-beta receptor type-1 |
CHEMBL4439 |
T204D |
851 |
21 |
0.9902 |
0.9999 |
| 1236 |
TGF-beta receptor type-1 |
CHEMBL4439 |
NA |
851 |
423 |
0.9902 |
0.9958 |
| 1237 |
TGF-beta receptor type-2 |
CHEMBL4267 |
NA |
131 |
22 |
0.9742 |
0.9579 |
| 1238 |
TP53-binding protein 1 |
CHEMBL2424509 |
NA |
53 |
22 |
0.9997 |
1 |
| 1239 |
TRAF2 and NCK-interacting protein kinase |
CHEMBL4527 |
NA |
175 |
11 |
0.954 |
0.8768 |
| 1240 |
Taste receptor type 2 member 14 |
CHEMBL3309105 |
NA |
34 |
25 |
0.9797 |
1 |
| 1241 |
Taste receptor type 2 member 8 |
CHEMBL3988599 |
NA |
44 |
32 |
1 |
1 |
| 1242 |
Tau-tubulin kinase 1 |
CHEMBL1926492 |
NA |
78 |
14 |
0.9998 |
1 |
| 1243 |
Telomerase reverse transcriptase |
CHEMBL2916 |
NA |
445 |
203 |
0.9806 |
0.9809 |
| 1244 |
Testis-specific chromodomain protein Y 1 |
CHEMBL3879864 |
NA |
42 |
12 |
0.9783 |
0.929 |
| 1245 |
Thioredoxin reductase 1, cytoplasmic |
CHEMBL1927 |
NA |
24 |
10 |
0.9408 |
0.9423 |
| 1246 |
Thrombopoietin receptor |
CHEMBL1864 |
NA |
167 |
131 |
0.9997 |
0.9999 |
| 1247 |
Thrombospondin-1 |
CHEMBL4630810 |
NA |
11 |
11 |
1 |
1 |
| 1248 |
Thromboxane A2 receptor |
CHEMBL2069 |
NA |
368 |
138 |
0.9901 |
0.9963 |
| 1249 |
Thromboxane-A synthase |
CHEMBL1835 |
NA |
63 |
22 |
0.9934 |
0.9946 |
| 1250 |
Thymidine phosphorylase |
CHEMBL3106 |
NA |
170 |
55 |
0.9986 |
1 |
| 1251 |
Thyroid hormone receptor |
CHEMBL2111462 |
NA |
35 |
33 |
0.999 |
0.9998 |
| 1252 |
Thyroid hormone receptor alpha |
CHEMBL1860 |
NA |
270 |
90 |
0.9989 |
0.9998 |
| 1253 |
Thyroid hormone receptor beta |
CHEMBL1947 |
NA |
467 |
137 |
0.9958 |
0.9956 |
| 1254 |
Thyrotropin receptor |
CHEMBL1963 |
NA |
53 |
41 |
0.9894 |
0.9734 |
| 1255 |
Tissue factor |
CHEMBL4081 |
NA |
140 |
78 |
0.9907 |
0.9897 |
| 1256 |
Tissue factor pathway inhibitor 2 |
CHEMBL6066240 |
NA |
25 |
12 |
0.9992 |
1 |
| 1257 |
Toll-like receptor 1/2 |
CHEMBL3885643 |
NA |
106 |
99 |
0.9952 |
0.9976 |
| 1258 |
Toll-like receptor 2 |
CHEMBL4163 |
NA |
174 |
73 |
0.992 |
0.9835 |
| 1259 |
Toll-like receptor 4 |
CHEMBL5255 |
NA |
157 |
79 |
0.9803 |
0.985 |
| 1260 |
Toll-like receptor 7 |
CHEMBL5936 |
NA |
1136 |
756 |
0.9933 |
0.9958 |
| 1261 |
Toll-like receptor 8 |
CHEMBL5805 |
NA |
509 |
230 |
0.9936 |
0.998 |
| 1262 |
Toll-like receptor 9 |
CHEMBL5804 |
NA |
243 |
165 |
0.9962 |
0.9955 |
| 1263 |
Trace amine-associated receptor 1 |
CHEMBL5857 |
NA |
195 |
129 |
0.9953 |
0.9998 |
| 1264 |
Transcription activator BRG1 |
CHEMBL3085620 |
NA |
59 |
13 |
0.9769 |
0.9718 |
| 1265 |
Transcription factor AP1 |
CHEMBL2111421 |
NA |
54 |
26 |
0.9807 |
0.9995 |
| 1266 |
Transcription factor Jun |
CHEMBL4977 |
NA |
68 |
24 |
0.9357 |
0.962 |
| 1267 |
Transcription factor p65 |
CHEMBL5533 |
NA |
79 |
19 |
0.9719 |
0.9254 |
| 1268 |
Transcription initiation factor TFIID subunit 1 |
CHEMBL3217390 |
NA |
147 |
62 |
0.9897 |
0.9807 |
| 1269 |
Transcription intermediary factor 1-alpha |
CHEMBL3108638 |
NA |
104 |
24 |
0.9891 |
0.9899 |
| 1270 |
Transcriptional activator Myb |
CHEMBL5169115 |
NA |
26 |
24 |
1 |
1 |
| 1271 |
Transcriptional enhancer factor TEF-1 |
CHEMBL3334416 |
NA |
31 |
10 |
0.9678 |
0.9311 |
| 1272 |
Transcriptional enhancer factor TEF-3 |
CHEMBL4295828 |
NA |
63 |
25 |
0.9798 |
0.9507 |
| 1273 |
Transforming protein RhoA |
CHEMBL6052 |
NA |
36 |
15 |
0.9971 |
0.9906 |
| 1274 |
Transient receptor potential cation channel subfamily A member 1 |
CHEMBL6007 |
NA |
521 |
219 |
0.9872 |
0.9933 |
| 1275 |
Transient receptor potential cation channel subfamily M member 2 |
CHEMBL1250402 |
NA |
33 |
10 |
0.9595 |
0.904 |
| 1276 |
Transient receptor potential cation channel subfamily M member 5 |
CHEMBL1628468 |
NA |
73 |
35 |
0.9852 |
1 |
| 1277 |
Transient receptor potential cation channel subfamily M member 8 |
CHEMBL1075319 |
NA |
430 |
248 |
0.9799 |
0.9866 |
| 1278 |
Transient receptor potential cation channel subfamily V member 1 |
CHEMBL4794 |
NA |
2160 |
1639 |
0.9901 |
0.9955 |
| 1279 |
Transient receptor potential cation channel subfamily V member 4 |
CHEMBL3119 |
NA |
297 |
198 |
0.9901 |
0.9986 |
| 1280 |
Transient receptor potential cation channel subfamily V member 6 |
CHEMBL1628465 |
NA |
45 |
13 |
0.9932 |
1 |
| 1281 |
Transitional endoplasmic reticulum ATPase |
CHEMBL1075145 |
NA |
326 |
79 |
0.9824 |
0.9956 |
| 1282 |
Transketolase |
CHEMBL4983 |
NA |
27 |
11 |
0.9757 |
0.9998 |
| 1283 |
Translocator protein |
CHEMBL5742 |
UNDEFINED MUTATION |
135 |
21 |
0.9562 |
0.999 |
| 1284 |
Translocator protein |
CHEMBL5742 |
NA |
135 |
50 |
0.9562 |
0.9973 |
| 1285 |
Transmembrane domain-containing protein TMIGD3 |
CHEMBL3712907 |
NA |
143 |
99 |
0.9933 |
0.9957 |
| 1286 |
Transmembrane protease serine 6 |
CHEMBL1795139 |
NA |
90 |
39 |
0.9997 |
0.9999 |
| 1287 |
Transthyretin |
CHEMBL3194 |
V50M |
179 |
23 |
0.9879 |
0.9673 |
| 1288 |
Transthyretin |
CHEMBL3194 |
NA |
179 |
64 |
0.9879 |
0.9964 |
| 1289 |
Trifunctional purine biosynthetic protein adenosine-3 |
CHEMBL3972 |
NA |
69 |
41 |
0.9826 |
0.9999 |
| 1290 |
Tryptophan 2,3-dioxygenase |
CHEMBL2140 |
NA |
497 |
127 |
0.9897 |
0.9989 |
| 1291 |
Tubulin beta-3 chain |
CHEMBL2597 |
NA |
13 |
11 |
0.9214 |
0.9103 |
| 1292 |
Tumor necrosis factor |
CHEMBL1825 |
NA |
155 |
65 |
0.9741 |
0.9767 |
| 1293 |
Tumor necrosis factor ligand superfamily member 11 |
CHEMBL2364162 |
NA |
35 |
12 |
0.9742 |
1 |
| 1294 |
Tumour suppressor p53/oncoprotein Mdm2 |
CHEMBL1907611 |
L33E |
579 |
13 |
0.9827 |
1 |
| 1295 |
Tumour suppressor p53/oncoprotein Mdm2 |
CHEMBL1907611 |
NA |
579 |
327 |
0.9827 |
0.9803 |
| 1296 |
Tumour suppressor protein p53/Mdm4 |
CHEMBL2221344 |
NA |
52 |
26 |
0.92 |
0.8719 |
| 1297 |
Type-1 angiotensin II receptor |
CHEMBL227 |
N111G |
391 |
15 |
0.9932 |
1 |
| 1298 |
Type-1 angiotensin II receptor |
CHEMBL227 |
NA |
391 |
155 |
0.9932 |
0.9977 |
| 1299 |
Type-2 angiotensin II receptor |
CHEMBL4607 |
NA |
137 |
94 |
0.9912 |
1 |
| 1300 |
Tyrosinase |
CHEMBL1973 |
NA |
196 |
41 |
0.989 |
0.9977 |
| 1301 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
NA |
1000 |
129 |
0.9725 |
0.9704 |
| 1302 |
Tyrosine-protein kinase ABL1 |
CHEMBL1862 |
T315I |
1000 |
232 |
0.9725 |
0.9867 |
| 1303 |
Tyrosine-protein kinase BTK |
CHEMBL5251 |
C481R |
2027 |
10 |
0.99 |
0.9925 |
| 1304 |
Tyrosine-protein kinase BTK |
CHEMBL5251 |
T474I |
2027 |
10 |
0.99 |
0.9756 |
| 1305 |
Tyrosine-protein kinase BTK |
CHEMBL5251 |
C481S |
2027 |
38 |
0.99 |
0.985 |
| 1306 |
Tyrosine-protein kinase BTK |
CHEMBL5251 |
NA |
2027 |
1034 |
0.99 |
0.9943 |
| 1307 |
Tyrosine-protein kinase Blk |
CHEMBL2250 |
NA |
163 |
64 |
0.9643 |
0.9871 |
| 1308 |
Tyrosine-protein kinase CSK |
CHEMBL2634 |
NA |
103 |
10 |
0.9471 |
0.8087 |
| 1309 |
Tyrosine-protein kinase Fer |
CHEMBL3982 |
NA |
52 |
20 |
0.932 |
0.9565 |
| 1310 |
Tyrosine-protein kinase Fyn |
CHEMBL1841 |
NA |
135 |
11 |
0.9419 |
0.8211 |
| 1311 |
Tyrosine-protein kinase HCK |
CHEMBL3234 |
NA |
110 |
12 |
0.9482 |
0.8897 |
| 1312 |
Tyrosine-protein kinase ITK/TSK |
CHEMBL2959 |
NA |
410 |
90 |
0.9839 |
0.9892 |
| 1313 |
Tyrosine-protein kinase JAK1 |
CHEMBL2835 |
NA |
1557 |
416 |
0.9878 |
0.9928 |
| 1314 |
Tyrosine-protein kinase JAK2 |
CHEMBL2971 |
V617F |
1936 |
76 |
0.9826 |
0.9743 |
| 1315 |
Tyrosine-protein kinase JAK2 |
CHEMBL2971 |
NA |
1936 |
511 |
0.9826 |
0.9915 |
| 1316 |
Tyrosine-protein kinase JAK3 |
CHEMBL2148 |
NA |
1593 |
482 |
0.9828 |
0.9916 |
| 1317 |
Tyrosine-protein kinase Lck |
CHEMBL258 |
NA |
771 |
59 |
0.96 |
0.9486 |
| 1318 |
Tyrosine-protein kinase Lyn |
CHEMBL3905 |
NA |
161 |
10 |
0.9546 |
0.856 |
| 1319 |
Tyrosine-protein kinase Mer |
CHEMBL5331 |
NA |
434 |
106 |
0.9806 |
0.9941 |
| 1320 |
Tyrosine-protein kinase SYK |
CHEMBL2599 |
NA |
716 |
296 |
0.9765 |
0.9985 |
| 1321 |
Tyrosine-protein kinase Tec |
CHEMBL4246 |
NA |
125 |
25 |
0.9755 |
0.9791 |
| 1322 |
Tyrosine-protein kinase ZAP-70 |
CHEMBL2803 |
NA |
99 |
11 |
0.9563 |
0.9621 |
| 1323 |
Tyrosine-protein kinase receptor TYRO3 |
CHEMBL5314 |
NA |
340 |
12 |
0.9816 |
0.8822 |
| 1324 |
Tyrosine-protein kinase receptor UFO |
CHEMBL4895 |
NA |
851 |
111 |
0.9815 |
0.9775 |
| 1325 |
Tyrosine-protein phosphatase non-receptor type 1 |
CHEMBL335 |
NA |
2229 |
267 |
0.979 |
0.9951 |
| 1326 |
Tyrosine-protein phosphatase non-receptor type 11 |
CHEMBL3864 |
NA |
775 |
165 |
0.9797 |
0.9835 |
| 1327 |
Tyrosine-protein phosphatase non-receptor type 2 |
CHEMBL3807 |
NA |
488 |
57 |
0.9859 |
0.9775 |
| 1328 |
Tyrosine-protein phosphatase non-receptor type 22 |
CHEMBL2889 |
NA |
118 |
32 |
0.9872 |
1 |
| 1329 |
Tyrosine-protein phosphatase non-receptor type 5 |
CHEMBL2007628 |
NA |
203 |
20 |
0.9865 |
0.9967 |
| 1330 |
Tyrosine-protein phosphatase non-receptor type 6 |
CHEMBL3166 |
NA |
173 |
19 |
0.9661 |
0.9719 |
| 1331 |
Tyrosyl-DNA phosphodiesterase 1 |
CHEMBL1075138 |
NA |
267 |
18 |
0.9868 |
0.9919 |
| 1332 |
Tyrosyl-DNA phosphodiesterase 2 |
CHEMBL2169736 |
NA |
231 |
26 |
0.9928 |
0.9997 |
| 1333 |
U5 small nuclear ribonucleoprotein 200 kDa helicase |
CHEMBL4105972 |
NA |
30 |
10 |
0.9817 |
1 |
| 1334 |
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 |
CHEMBL3430885 |
NA |
98 |
58 |
0.9774 |
0.9999 |
| 1335 |
Ubiquitin carboxyl-terminal hydrolase 2 |
CHEMBL1293227 |
NA |
39 |
14 |
0.9296 |
0.9849 |
| 1336 |
Ubiquitin carboxyl-terminal hydrolase 5 |
CHEMBL6158 |
NA |
52 |
10 |
0.9616 |
0.9519 |
| 1337 |
Ubiquitin carboxyl-terminal hydrolase 7 |
CHEMBL2157850 |
NA |
420 |
34 |
0.9925 |
0.9822 |
| 1338 |
Ubiquitin carboxyl-terminal hydrolase 8 |
CHEMBL2157854 |
NA |
68 |
23 |
0.9959 |
0.9904 |
| 1339 |
Ubiquitin-like modifier-activating enzyme ATG7 |
CHEMBL2321621 |
NA |
31 |
20 |
1 |
1 |
| 1340 |
Urokinase-type plasminogen activator |
CHEMBL3286 |
NA |
395 |
19 |
0.9851 |
0.9997 |
| 1341 |
Urotensin-2 receptor |
CHEMBL3764 |
NA |
482 |
378 |
0.9968 |
0.9974 |
| 1342 |
Utrophin |
CHEMBL4523230 |
NA |
58 |
42 |
1 |
1 |
| 1343 |
Vascular endothelial growth factor receptor 1 |
CHEMBL1868 |
NA |
412 |
26 |
0.9603 |
0.9231 |
| 1344 |
Vascular endothelial growth factor receptor 2 |
CHEMBL279 |
NA |
4227 |
1074 |
0.9653 |
0.9894 |
| 1345 |
Vascular endothelial growth factor receptor 3 |
CHEMBL1955 |
NA |
218 |
22 |
0.9418 |
0.8666 |
| 1346 |
Vasopressin V1a receptor |
CHEMBL1889 |
NA |
783 |
570 |
0.9917 |
0.9964 |
| 1347 |
Vasopressin V1b receptor |
CHEMBL1921 |
NA |
396 |
322 |
0.9954 |
0.9987 |
| 1348 |
Vasopressin V2 receptor |
CHEMBL1790 |
NA |
511 |
344 |
0.9912 |
0.9955 |
| 1349 |
Very long chain fatty acid elongase 1 |
CHEMBL6001 |
NA |
66 |
56 |
0.9944 |
1 |
| 1350 |
Very long chain fatty acid elongase 6 |
CHEMBL5704 |
NA |
44 |
30 |
1 |
1 |
| 1351 |
Vesicular acetylcholine transporter |
CHEMBL4767 |
NA |
34 |
28 |
0.9998 |
1 |
| 1352 |
Vitamin D3 receptor |
CHEMBL1977 |
NA |
377 |
182 |
0.9934 |
0.9967 |
| 1353 |
Vitamin K epoxide reductase complex subunit 1 |
CHEMBL1930 |
NA |
17 |
10 |
0.9988 |
0.9992 |
| 1354 |
Voltage-dependent L-type calcium channel subunit alpha-1C |
CHEMBL1940 |
NA |
75 |
12 |
0.8779 |
1 |
| 1355 |
Voltage-dependent N-type calcium channel subunit alpha-1B |
CHEMBL4478 |
NA |
410 |
160 |
0.9937 |
0.9996 |
| 1356 |
Voltage-dependent T-type calcium channel subunit alpha-1G |
CHEMBL4641 |
NA |
413 |
257 |
0.9935 |
0.9956 |
| 1357 |
Voltage-dependent T-type calcium channel subunit alpha-1H |
CHEMBL1859 |
NA |
376 |
291 |
0.995 |
0.9979 |
| 1358 |
Voltage-dependent T-type calcium channel subunit alpha-1I |
CHEMBL5558 |
NA |
166 |
153 |
0.9974 |
0.9969 |
| 1359 |
Voltage-dependent calcium channel subunit alpha-2/delta-1 |
CHEMBL1919 |
NA |
169 |
110 |
0.9973 |
0.9975 |
| 1360 |
Voltage-gated inwardly rectifying potassium channel KCNH2 |
CHEMBL240 |
NA |
7553 |
2061 |
0.9255 |
0.9439 |
| 1361 |
Voltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3) |
CHEMBL2221348 |
NA |
67 |
58 |
0.9993 |
0.9992 |
| 1362 |
Von Hippel-Lindau disease tumor suppressor/Elongin B/Elongin C |
CHEMBL3301400 |
NA |
94 |
67 |
0.9982 |
0.9993 |
| 1363 |
WD repeat-containing protein 5 |
CHEMBL1075317 |
NA |
368 |
179 |
0.9915 |
0.9975 |
| 1364 |
Wee1-like protein kinase |
CHEMBL5491 |
NA |
480 |
81 |
0.9948 |
0.9986 |
| 1365 |
Xanthine dehydrogenase/oxidase |
CHEMBL1929 |
NA |
395 |
29 |
0.9852 |
0.9984 |
| 1366 |
YAP1-TEAD4 |
CHEMBL5465250 |
NA |
29 |
14 |
1 |
1 |
| 1367 |
YEATS domain-containing protein 4 |
CHEMBL4296266 |
NA |
15 |
13 |
0.999 |
1 |
| 1368 |
Zinc finger protein Aiolos |
CHEMBL4739707 |
NA |
14 |
12 |
0.9999 |
0.9998 |
| 1369 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial |
CHEMBL4766 |
NA |
178 |
67 |
0.9453 |
0.9616 |
| 1370 |
beta-catenin-B-cell lymphoma 9 protein complex |
CHEMBL3885525 |
NA |
200 |
115 |
0.9942 |
0.9939 |
| 1371 |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
CHEMBL4409 |
NA |
1126 |
400 |
0.9891 |
0.995 |
| 1372 |
cGMP-dependent 3',5'-cyclic phosphodiesterase |
CHEMBL2652 |
NA |
510 |
127 |
0.9856 |
0.9935 |
| 1373 |
cGMP-dependent protein kinase 1 |
CHEMBL4273 |
NA |
82 |
14 |
0.9582 |
0.9939 |
| 1374 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A |
CHEMBL241 |
NA |
268 |
33 |
0.9743 |
0.9992 |
| 1375 |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B |
CHEMBL290 |
NA |
133 |
15 |
0.9836 |
0.949 |
| 1376 |
cGMP-specific 3',5'-cyclic phosphodiesterase |
CHEMBL1827 |
NA |
903 |
322 |
0.9821 |
0.9985 |
| 1377 |
dCTP pyrophosphatase 1 |
CHEMBL3769292 |
NA |
173 |
85 |
0.9896 |
1 |
| 1378 |
eIF-2-alpha kinase GCN2 |
CHEMBL5358 |
NA |
93 |
46 |
0.9799 |
0.9969 |
| 1379 |
fMet-Leu-Phe receptor |
CHEMBL3359 |
NA |
308 |
141 |
0.9956 |
0.9978 |
| 1380 |
mTORC1 |
CHEMBL4296661 |
NA |
162 |
156 |
0.9864 |
0.986 |
| 1381 |
mTORC2 |
CHEMBL4523999 |
NA |
97 |
91 |
0.9843 |
0.9828 |
| 1382 |
von Hippel-Lindau disease tumor suppressor |
CHEMBL3108660 |
NA |
168 |
53 |
0.9988 |
0.9999 |
| 1383 |
von Hippel-Lindau disease tumor suppressor/Bromodomain-containing protein 4 |
CHEMBL4296140 |
NA |
14 |
13 |
0.9998 |
0.9999 |