Arachidonic Acid

Representations & DB's id
ChEBI:	CHEBI:15843
ChEMBL:	CHEMBL15594
PubChem:	444899
IUPAC:	(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
Standard InChI:	InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
Standard InChI Key:	YZXBAPSDXZZRGB-DOFZRALJSA-N
SMILES:	CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)O

Molecular propeties
AlogP:	6.22
Hydrogen bonds acceptors:	1
Hydrogen bonds donors:	1
Rotatable bonds:	14
Number of rings:	0
Molecular Weight:	304.24
Topological polar surface area:	37.3
Number of aromatic rings:	0
Fsp3:	0.55
Number of carbons:	20

Plant sources

Part of plant	Plant name	Ref.
Plant	Cannabis sativa
Plant	Silybum marianum

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID
IC50	200000 nM	Cytochrome P450 51	Q16850
IC50	105000 nM	Coagulation factor III	P13726
Others	11.5 %	Cytochrome P450 19A1	P11511
IC50	28200 nM	Cytochrome P450 19A1	P11511
Others	147.2 %	Cytochrome P450 19A1	P11511
Potency	15848.9 nM	Prelamin-A/C	P02545
Potency	2238.7 nM	ATP-dependent DNA helicase Q1	P46063
Potency	44668.4 nM	ATP-dependent DNA helicase Q1	P46063
Potency	3981.1 nM	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Q99714
Potency	1995.3 nM	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Q99714
Potency	28183.8 nM	Lysine-specific demethylase 4D-like	B2RXH2
Potency	25118.9 nM	Lysine-specific demethylase 4D-like	B2RXH2
Potency	17782.8 nM	Tyrosyl-DNA phosphodiesterase 1	Q9NUW8
Potency	28183.8 nM	Microtubule-associated protein tau	P10636
Potency	12589.3 nM	Microtubule-associated protein tau	P10636
Potency	7943.3 nM	Aldehyde dehydrogenase 1A1	P00352
Potency	2818.4 nM	Aldehyde dehydrogenase 1A1	P00352
Potency	79.4 nM	Arachidonate 15-lipoxygenase	P16050
Potency	316.2 nM	Arachidonate 15-lipoxygenase	P16050
Potency	31622.8 nM	Microtubule-associated protein tau	P10636
Potency	14125.4 nM	Microtubule-associated protein tau	P10636
Potency	39810.7 nM	Lethal(3)malignant brain tumor-like protein 1	Q9Y468
Potency	3162.3 nM	Ubiquitin carboxyl-terminal hydrolase 2	O75604
Potency	15848.9 nM	15-hydroxyprostaglandin dehydrogenase [NAD+]	P15428
Potency	19952.6 nM	15-hydroxyprostaglandin dehydrogenase [NAD+]	P15428
Potency	31622.8 nM	Cellular tumor antigen p53	P04637
Potency	31622.8 nM	Caspase-1	P29466
Potency	25118.9 nM	Bloom syndrome protein	P54132
Potency	39810.7 nM	Cytochrome P450 3A4	P08684
Potency	7943.3 nM	Cytochrome P450 3A4	P08684
Potency	39810.7 nM	Cytochrome P450 3A4	P08684
Potency	7943.3 nM	Cytochrome P450 3A4	P08684
Potency	22387.2 nM	Histone acetyltransferase GCN5	Q92830
Potency	39810.7 nM	Histone acetyltransferase GCN5	Q92830
Potency	15848.9 nM	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Q96KQ7
Potency	31622.8 nM	Arachidonate 15-lipoxygenase, type II	O15296
IC50	1200 nM	Peroxisome proliferator-activated receptor alpha	Q07869
IC50	3100 nM	Peroxisome proliferator-activated receptor delta	Q03181
IC50	1600 nM	Peroxisome proliferator-activated receptor gamma	P37231
IC50	1200 nM	Peroxisome proliferator-activated receptor alpha	Q07869

Arachidonic Acid

Representations & DB's id

Molecular propeties

Plant sources

In vitro data