Phyto4Health

Rhamnetin

Representations & DB's id
ChEBI: CHEBI:74992
ChEMBL: CHEMBL312163
PubChem: 5281691
IUPAC: 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one
Standard InChI: InChI=1S/C16H12O7/c1-22-8-5-11(19)13-12(6-8)23-16(15(21)14(13)20)7-2-3-9(17)10(18)4-7/h2-6,17-19,21H,1H3
Standard InChI Key: JGUZGNYPMHHYRK-UHFFFAOYSA-N
SMILES: COc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O

Molecular propeties
AlogP: 2.29
Hydrogen bonds acceptors: 7
Hydrogen bonds donors: 4
Rotatable bonds: 2
Number of rings: 3
Molecular Weight: 316.06
Topological polar surface area: 116
Number of aromatic rings: 3
Fsp3: 0.062
Number of carbons: 16

Plant sources

Part of plant Plant name Ref.
NigraSesamum indicum
PlantPelargonium roseum
FlowerCrocus sativus

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Others8.1 %Salivary alpha-amylaseP04745
Potency11220.2 nMPrelamin-A/CP02545
Potency1995.3 nMATP-dependent DNA helicase Q1P46063
Potency19952.6 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency22387.2 nMLysine-specific demethylase 4D-likeB2RXH2
Potency31622.8 nMTyrosyl-DNA phosphodiesterase 1Q9NUW8
Potency50118.7 nMThyroid hormone receptor beta-1P10828
Potency79432.8 nMThyroid hormone receptor beta-1P10828
Potency5011.9 nMMicrotubule-associated protein tauP10636
Potency39810.7 nMCytochrome P450 3A4P08684
Potency39810.7 nMCytochrome P450 3A4P08684
Potency12589.3 nMArachidonate 15-lipoxygenase, type IIO15296
IC502700 nMAldose reductaseP15121