Diosmin

Representations & DB's id
ChEBI:	CHEBI:4631
ChEMBL:	CHEMBL231884
PubChem:	5281613
IUPAC:	5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
Standard InChI:	InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
Standard InChI Key:	GZSOSUNBTXMUFQ-YFAPSIMESA-N
SMILES:	COc1ccc(cc1O)c1cc(=O)c2c(o1)cc(cc2O)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)[C@H]([C@@H]([C@H]1O)O)O

Molecular propeties
AlogP:	-1.09
Hydrogen bonds acceptors:	15
Hydrogen bonds donors:	8
Rotatable bonds:	7
Number of rings:	5
Molecular Weight:	608.17
Topological polar surface area:	234
Number of aromatic rings:	3
Fsp3:	0.464
Number of carbons:	28

Plant sources

Part of plant	Plant name	Ref.
Pericarpium	Citrus unshiu
Plant	Nicotiana tabacum

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID	Ref.
Potency	31622.8 nM	Histone-lysine N-methyltransferase MLL	Q03164
Potency	25118.9 nM	DNA polymerase beta	P06746
Potency	19952.6 nM	Lysine-specific demethylase 4A	O75164
Potency	39810.7 nM	Histone acetyltransferase GCN5	Q92830
Potency	5802.4 nM	ATPase family AAA domain-containing protein 5	Q96QE3
Potency	562.3 nM	Geminin	O75496