Phyto4Health

Naphthalen-1-Amine

Representations & DB's id
ChEBI: CHEBI:50450
ChEMBL: CHEMBL57394
PubChem: 8640
IUPAC: naphthalen-1-amine
Standard InChI: InChI=1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2
Standard InChI Key: RUFPHBVGCFYCNW-UHFFFAOYSA-N
SMILES: Nc1cccc2c1cccc2

Molecular propeties
AlogP: 2.42
Hydrogen bonds acceptors: 1
Hydrogen bonds donors: 1
Rotatable bonds: 0
Number of rings: 2
Molecular Weight: 143.07
Topological polar surface area: 26
Number of aromatic rings: 2
Fsp3: 0
Number of carbons: 10

Plant sources

Part of plant Plant name Ref.
FructusCapsicum annuum

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Potency31622.8 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency39810.7 nMThyroid stimulating hormone receptorP16473
Potency19952.6 nMAldehyde dehydrogenase 1A1P00352
Potency39810.7 nMThyroid stimulating hormone receptorP16473
Potency10000 nM15-hydroxyprostaglandin dehydrogenase [NAD+]P15428
Potency31622.8 nMCytochrome P450 3A4P08684
Potency31622.8 nMCytochrome P450 3A4P08684
Others0 pm/min/mgUDP-glucuronosyltransferase 1-1P22309
Others0 pm/min/mgUDP-glucuronosyltransferase 1-10Q9HAW8
Others12 pm/min/mgUDP-glucuronosyltransferase 1-3P35503
Others360 pm/min/mgUDP-glucuronosyltransferase 1A4P22310
Others10600 pm/min/mgUDP-glucuronosyltransferase 1-6P19224
Others0 pm/min/mgUDP-glucuronosyltransferase 1-7Q9HAW7
Others1800 pm/min/mgUDP-glucuronosyltransferase 1-9O60656
Others22 pm/min/mgUDP-glucuronosyltransferase 2A1Q9Y4X1
Others0 pm/min/mgUDP-glucuronosyltransferase 2B15P54855
Potency44668.4 nMAryl hydrocarbon receptorP35869
Potency37578 nMNuclear factor erythroid 2-related factor 2Q16236