Flucort

Representations & DB's id
ChEBI:	None
ChEMBL:	CHEMBL1599911
PubChem:	3381
IUPAC:	12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Standard InChI:	InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3
Standard InChI Key:	FEBLZLNTKCEFIT-UHFFFAOYSA-N
SMILES:	OCC(=O)C12OC(OC1CC1C2(C)CC(O)C2(C1CC(C1=CC(=O)C=CC21C)F)F)(C)C

Molecular propeties
AlogP:	2.37
Hydrogen bonds acceptors:	6
Hydrogen bonds donors:	2
Rotatable bonds:	2
Number of rings:	5
Molecular Weight:	452.2
Topological polar surface area:	93.1
Number of aromatic rings:	0
Fsp3:	0.75
Number of carbons:	24

Plant sources

Part of plant	Plant name	Ref.
Plant	Pimpinella anisum
Plant	Vaccinium vitis-idaea

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID	Ref.
Potency	316.2 nM	Prelamin-A/C	P02545
Potency	25918.5 nM	ATPase family AAA domain-containing protein 5	Q96QE3
Potency	7079.5 nM	Guanine nucleotide-binding protein G(s), subunit alpha	P63092