Galangin

Representations & DB's id
ChEBI:	CHEBI:5262
ChEMBL:	CHEMBL309490
PubChem:	5281616
IUPAC:	3,5,7-trihydroxy-2-phenylchromen-4-one
Standard InChI:	InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
Standard InChI Key:	VCCRNZQBSJXYJD-UHFFFAOYSA-N
SMILES:	Oc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccccc1

Molecular propeties
AlogP:	2.58
Hydrogen bonds acceptors:	5
Hydrogen bonds donors:	3
Rotatable bonds:	1
Number of rings:	3
Molecular Weight:	270.05
Topological polar surface area:	87
Number of aromatic rings:	3
Fsp3:	0
Number of carbons:	15

Plant sources

Part of plant	Plant name	Ref.
Plant	Plantago major
Plant	Glycyrrhiza uralensis

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID
Ki	16700 nM	Adenosine A2a receptor	P29274
Ki	18100 nM	Adenosine A2a receptor	P29274
Ki	33000 nM	Adenosine A2a receptor	P29274
Ki	3150 nM	Adenosine A3 receptor	P0DMS8
Ki	100000 nM	Cytochrome P450 19A1	P11511
Ki	6900 nM	Butyrylcholinesterase	P06276
Ki	85600 nM	Acetylcholinesterase	P22303
IC50	77 nM	Cytochrome P450 1A1	P04798
IC50	40 nM	Cytochrome P450 1A2	P05177
IC50	25 nM	Cytochrome P450 1B1	Q16678
Potency	3981.1 nM	Cytochrome P450 2C19	P33261
Potency	11220.2 nM	Microtubule-associated protein tau	P10636
Potency	15848.9 nM	Cytochrome P450 3A4	P08684
Potency	19952.6 nM	Cytochrome P450 2D6	P10635
Potency	15848.9 nM	Cytochrome P450 3A4	P08684
Potency	3162.3 nM	Cytochrome P450 2C9	P11712
Potency	12990 nM	ATPase family AAA domain-containing protein 5	Q96QE3
Others	115 pm/min/mg	UDP-glucuronosyltransferase 1-1	P22309
Others	80 pm/min/mg	UDP-glucuronosyltransferase 1-1	P22309
Others	610 pm/min/mg	UDP-glucuronosyltransferase 1-3	P35503
Others	0 pm/min/mg	UDP-glucuronosyltransferase 1A4	P22310
Others	0 pm/min/mg	UDP-glucuronosyltransferase 1-6	P19224
Others	2500 pm/min/mg	UDP-glucuronosyltransferase 1-9	O60656
Others	65 pm/min/mg	UDP-glucuronosyltransferase 2B15	P54855
Potency	32642.7 nM	Geminin	O75496
Potency	12589.3 nM	Glutaminase kidney isoform, mitochondrial	O94925
Potency	22387.2 nM	Breast cancer type 1 susceptibility protein	P38398
IC50	12 nM	Acetylcholinesterase	P22303
IC50	10000 nM	Tyrosine-protein kinase receptor FLT3	P36888
Ki	10000 nM	Carbonic anhydrase II	P00918
Ki	10000 nM	Carbonic anhydrase I	P00915
Ki	568.3 nM	Carbonic anhydrase IV	P22748
Ki	24.5 nM	Carbonic anhydrase VII	P43166
Ki	41.8 nM	Carbonic anhydrase XII	O43570
Others	95 %	Isocitrate dehydrogenase [NADP] cytoplasmic	O75874
Others	89.1 %	Isocitrate dehydrogenase [NADP] cytoplasmic	O75874
IC50	500000 nM	Beta amyloid A4 protein	P05067

Galangin

Representations & DB's id

Molecular propeties

Plant sources

In vitro data