3,5-Dihydroxy-2-Phenylchromen-4-One

Representations & DB's id
ChEBI:	None
ChEMBL:	CHEMBL239276
PubChem:	5393151
IUPAC:	3,5-dihydroxy-2-phenylchromen-4-one
Standard InChI:	InChI=1S/C15H10O4/c16-10-7-4-8-11-12(10)13(17)14(18)15(19-11)9-5-2-1-3-6-9/h1-8,16,18H
Standard InChI Key:	QHYWQIVTVQAKQF-UHFFFAOYSA-N
SMILES:	Oc1cccc2c1c(=O)c(c(o2)c1ccccc1)O

Molecular propeties
AlogP:	2.87
Hydrogen bonds acceptors:	4
Hydrogen bonds donors:	2
Rotatable bonds:	1
Number of rings:	3
Molecular Weight:	254.06
Topological polar surface area:	66.8
Number of aromatic rings:	3
Fsp3:	0
Number of carbons:	15

Plant sources

Part of plant	Plant name	Ref.
Plant	Chamaemelum nobile

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID	Ref.
Potency	35481.3 nM	Prelamin-A/C	P02545
Potency	25118.9 nM	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Q99714
Potency	39810.7 nM	Lysine-specific demethylase 4D-like	B2RXH2
Potency	5623.4 nM	Microtubule-associated protein tau	P10636
Potency	1995.3 nM	Arachidonate 15-lipoxygenase	P16050
Potency	39810.7 nM	MAP kinase ERK2	P28482
Potency	12589.3 nM	Ubiquitin carboxyl-terminal hydrolase 2	O75604
Potency	5623.4 nM	15-hydroxyprostaglandin dehydrogenase [NAD+]	P15428
Potency	31622.8 nM	Cellular tumor antigen p53	P04637
Potency	3162.3 nM	Cellular tumor antigen p53	P04637
Potency	12589.3 nM	Cytochrome P450 3A4	P08684
Potency	12589.3 nM	Cytochrome P450 3A4	P08684