Phyto4Health

Pinosylvin Methyl Ether

Representations & DB's id
ChEBI: CHEBI:8227
ChEMBL: CHEMBL186366
PubChem: 5281719
IUPAC: 3-methoxy-5-[(E)-2-phenylethenyl]phenol
Standard InChI: InChI=1S/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7+
Standard InChI Key: JVIXPWIEOVZVJC-BQYQJAHWSA-N
SMILES: COc1cc(/C=C/c2ccccc2)cc(c1)O

Molecular propeties
AlogP: 3.57
Hydrogen bonds acceptors: 2
Hydrogen bonds donors: 1
Rotatable bonds: 3
Number of rings: 2
Molecular Weight: 226.1
Topological polar surface area: 29.5
Number of aromatic rings: 2
Fsp3: 0.067
Number of carbons: 15

Plant sources

Part of plant Plant name Ref.
PlantAnacyclus pyrethrum

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Potency19952.6 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency25118.9 nMLysine-specific demethylase 4D-likeB2RXH2
Potency25118.9 nMSurvival motor neuron proteinQ16637
Potency39810.7 nMAldehyde dehydrogenase 1A1P00352
Potency28183.8 nMMicrotubule-associated protein tauP10636
Potency25118.9 nMUbiquitin carboxyl-terminal hydrolase 2O75604
Potency28183.8 nM15-hydroxyprostaglandin dehydrogenase [NAD+]P15428
Potency7943.3 nMCellular tumor antigen p53P04637
Potency10000 nMCellular tumor antigen p53P04637
Potency31622.8 nMCytochrome P450 3A4P08684
Potency31622.8 nMCytochrome P450 3A4P08684
Potency29092.9 nMGemininO75496
Potency29092.9 nMGemininO75496
Potency28183.8 nMGlucagon-like peptide 1 receptorP43220
Potency3162.3 nMBreast cancer type 1 susceptibility proteinP38398
Potency3548.1 nMGuanine nucleotide-binding protein G(s), subunit alphaP63092
IC5010000 nMVanilloid receptorQ8NER1
IC5015000 nMVanilloid receptorQ8NER1
IC5030000 nMVanilloid receptorQ8NER1
IC5023700 nMVanilloid receptorQ8NER1