Phyto4Health

Chelerythrine

Representations & DB's id

ChEBI: CHEBI:78373
ChEMBL: CHEMBL13045
PubChem: 2703
IUPAC: 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
Standard InChI: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1
Standard InChI Key: LLEJIEBFSOEYIV-UHFFFAOYSA-N
SMILES: COc1c(OC)ccc2c1c[n+](C)c1c2ccc2c1cc1OCOc1c2

Molecular propeties

AlogP: 3.72
Hydrogen bonds acceptors: 4
Hydrogen bonds donors: 0
Rotatable bonds: 2
Number of rings: 5
Molecular Weight: 348.12
Topological polar surface area: 40.8
Number of aromatic rings: 4
Fsp3: 0.19
Number of carbons: 21

Plant sources

Part of plant Plant name Ref.
PlantPapaver commutatum
PlantConium maculatum
HerbaChelidonium majus
HerbaChelidonium majus

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Potency70794.6 nMThyroid hormone receptor beta-1P10828
Potency11220.2 nMNuclear factor NF-kappa-B p105 subunitP19838
Potency25118.9 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency46109.1 nMRas-related protein Rab-9AP51151
Potency7079.5 nMSurvival motor neuron proteinQ16637
Potency25118.9 nMThyroid stimulating hormone receptorP16473
Potency63095.7 nMTyrosyl-DNA phosphodiesterase 1Q9NUW8
Potency10000 nMCytochrome P450 2C19P33261
Potency15848.9 nMMicrotubule-associated protein tauP10636
Potency15848.9 nMMicrotubule-associated protein tauP10636
Potency31622.8 nMHypoxia-inducible factor 1 alphaQ16665
Potency22387.2 nMAldehyde dehydrogenase 1A1P00352
Potency15848.9 nMAldehyde dehydrogenase 1A1P00352
Potency19952.6 nMArachidonate 15-lipoxygenaseP16050
Potency501.2 nMMicrotubule-associated protein tauP10636
Potency31622.8 nMHypoxia-inducible factor 1 alphaQ16665
Potency31622.8 nMMAP kinase ERK2P28482
Potency12589.3 nMArachidonate 12-lipoxygenaseP18054
Potency11220.2 nMNuclear factor NF-kappa-B p105 subunitP19838
Potency25118.9 nMThyroid stimulating hormone receptorP16473
Potency58047.9 nMNiemann-Pick C1 proteinO15118
Potency25118.9 nMUbiquitin carboxyl-terminal hydrolase 2O75604
Potency2930.9 nMSerine/threonine-protein kinase mTORP42345
Potency19952.6 nM15-hydroxyprostaglandin dehydrogenase [NAD+]P15428
Potency1995.3 nMThrombopoietinP40225
Potency19952.6 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency5011.9 nMCellular tumor antigen p53P04637
Potency12589.3 nMCellular tumor antigen p53P04637
Potency25118.9 nMCytochrome P450 2D6P10635
Potency31622.8 nMCytochrome P450 3A4P08684
Potency31622.8 nMCytochrome P450 3A4P08684
Potency39810.7 nMCytochrome P450 2C9P11712
Potency1995.3 nMThrombopoietinP40225
Potency16353.5 nMATPase family AAA domain-containing protein 5Q96QE3
Potency16360.1 nMNuclear factor erythroid 2-related factor 2Q16236
Potency31622.8 nMHistone acetyltransferase GCN5Q92830
Potency16833.6 nMHistone-lysine N-methyltransferase, H3 lysine-9 specific 3Q96KQ7
Potency50118.7 nMChromobox protein homolog 1P83916
Potency15848.9 nMArachidonate 15-lipoxygenase, type IIO15296
Potency12589.3 nMArachidonate 15-lipoxygenase, type IIO15296
Potency29934.9 nMFlap endonuclease 1P39748
Potency5623.4 nMAtaxin-2Q99700
Others13.1 %Solute carrier organic anion transporter family member 2B1O94956
Others24.9 %Solute carrier organic anion transporter family member 1B3Q9NPD5
Others-0.7 %Solute carrier organic anion transporter family member 1B1Q9Y6L6
Others91 %Serine/threonine-protein kinase MARK1Q9P0L2
Others110 %Serine/threonine-protein kinase SRPK3Q9UPE1
Others66 %Serine/threonine-protein kinase SRPK3Q9UPE1
Others100 %Serine/threonine-protein kinase NEK7Q8TDX7
Others137 %Serine/threonine-protein kinase NEK7Q8TDX7
Others82 %Tyrosine-protein kinase ABL2P42684
Others83 %Serine/threonine-protein kinase Aurora-AO14965
Others96 %Casein kinase I deltaP48730
Others94 %Death-associated protein kinase 1P53355
Others107 %Ephrin type-A receptor 5P54756
Others57 %Fibroblast growth factor receptor 3P22607
Others115 %Fibroblast growth factor receptor 4P22455
Others63 %Tyrosine-protein kinase FYNP06241
Others92 %Tyrosine-protein kinase HCKP08631
Others83 %Inhibitor of nuclear factor kappa B kinase alpha subunitO15111
Others101 %Inhibitor of nuclear factor kappa B kinase beta subunitO14920
Others63 %c-Jun N-terminal kinase 3P53779
Others125 %Dual specificity mitogen-activated protein kinase kinase 1Q02750
Others119 %Dual specificity mitogen-activated protein kinase kinase 1Q02750
Others92 %Serine/threonine-protein kinase MST1Q13043
Others92 %Serine/threonine protein kinase NLKQ9UBE8
Others75 %Serine/threonine-protein kinase Aurora-AO14965
Others103 %Casein kinase I deltaP48730
Others71 %Death-associated protein kinase 1P53355
Others99 %Death-associated protein kinase 2Q9UIK4
Others99 %Ephrin type-A receptor 5P54756
Others94 %Ephrin type-A receptor 7Q15375
Others100 %Fibroblast growth factor receptor 4P22455
Others103 %Mitogen-activated protein kinase kinase kinase kinase 2Q12851
Others72 %Mitogen-activated protein kinase kinase kinase kinase 2Q12851
Others138 %Insulin-like growth factor I receptorP08069
Others131 %Insulin-like growth factor I receptorP08069
Others84 %Inhibitor of nuclear factor kappa B kinase beta subunitO14920
Others101 %Vascular endothelial growth factor receptor 2P35968
Others90 %Vascular endothelial growth factor receptor 2P35968
Others84 %Maternal embryonic leucine zipper kinaseQ14680
Others98 %Serine/threonine-protein kinase MST1Q13043
Others107 %Serine/threonine-protein kinase MST2Q13188
Others76 %Serine/threonine protein kinase NLKQ9UBE8
Others102 %Serine/threonine-protein kinase PAK 2Q13177
Others130 %Serine/threonine-protein kinase Aurora-BQ96GD4
Others60 %Serine/threonine-protein kinase Aurora-BQ96GD4
Others91 %Death-associated protein kinase 2Q9UIK4
Others79 %Ephrin type-A receptor 7Q15375
Others115 %Tyrosine-protein kinase FERP16591
Others80 %Tyrosine-protein kinase FERP16591
Others103 %G protein-coupled receptor kinase 5P34947
Others93 %Insulin-like growth factor I receptorP08069
Others117 %Insulin receptorP06213
Others130 %Insulin receptorP06213
Others108 %LIM domain kinase 1P53667
Others31 %Maternal embryonic leucine zipper kinaseQ14680
Others97 %Misshapen-like kinase 1Q8N4C8
Others94 %Serine/threonine-protein kinase MST2Q13188
Others81 %Serine/threonine-protein kinase PAK 2Q13177
Others104 %Serine/threonine-protein kinase Aurora-CQ9UQB9
Others126 %Casein kinase II alpha (prime)P19784
Others101 %Casein kinase II alpha (prime)P19784
Others98 %Serine/threonine-protein kinase DCLK2Q8N568
Others90 %Serine/threonine-protein kinase DCLK2Q8N568
Others108 %Ephrin type-A receptor 8P29322
Others101 %Ephrin type-A receptor 8P29322
Others82 %G protein-coupled receptor kinase 5P34947
Others96 %G protein-coupled receptor kinase 6P43250
Others99 %Insulin receptorP06213
Others87 %LIM domain kinase 1P53667
Others102 %Serine/threonine-protein kinase 11Q15831
Others75 %Misshapen-like kinase 1Q8N4C8
Others73 %Serine/threonine-protein kinase 24Q9Y6E0
Others73 %Serine/threonine-protein kinase 24Q9Y6E0
Others72 %Serine/threonine-protein kinase PAK 3O75914
Others83 %Serine/threonine-protein kinase PAK 3O75914
Others90 %Serine/threonine-protein kinase Aurora-CQ9UQB9
Others93 %Tyrosine-protein kinase receptor UFOP30530
Others120 %Dual specificity protein kinase CLK2P49760
Others102 %Discoidin domain-containing receptor 2Q16832
Others89 %Ephrin type-B receptor 1P54762
Others93 %G protein-coupled receptor kinase 6P43250
Others84 %Insulin receptorP06213
Others90 %Serine/threonine-protein kinase 11Q15831
Others102 %Dual specificity mitogen-activated protein kinase kinase 6P52564
Others130 %Dual specificity mitogen-activated protein kinase kinase 6P52564
Others102 %Proto-oncogene tyrosine-protein kinase MERQ12866
Others84 %Tyrosine kinase non-receptor protein 2Q07912
Others68 %Tyrosine kinase non-receptor protein 2Q07912
Others44 %Tyrosine-protein kinase receptor UFOP30530
Others93 %Dual specificity protein kinase CLK2P49760
Others74 %Dual specificity protein kinase CLK3P49761
Others94 %Discoidin domain-containing receptor 2Q16832
Others111 %Myotonin-protein kinaseQ09013
Others91 %Ephrin type-B receptor 1P54762
Others121 %Ephrin type-B receptor 2P29323
Others99 %G protein-coupled receptor kinase 7Q8WTQ7
Others91 %G protein-coupled receptor kinase 7Q8WTQ7
Others96 %Interleukin-1 receptor-associated kinase 1P51617
Others83 %Interleukin-1 receptor-associated kinase 1P51617
Others100 %Serine/threonine-protein kinase 10O94804
Others93 %Serine/threonine-protein kinase 10O94804
Others110 %Dual specificity mitogen-activated protein kinase kinase 7O14733
Others96 %Proto-oncogene tyrosine-protein kinase MERQ12866
Others94 %Hepatocyte growth factor receptorP08581
Others92 %ALK tyrosine kinase receptorQ9UM73
Others110 %Tyrosine-protein kinase BRKQ13882
Others101 %Tyrosine-protein kinase BRKQ13882
Others80 %Dual specificity protein kinase CLK3P49761
Others126 %Myotonin-protein kinaseQ09013
Others121 %Ephrin type-B receptor 2P29323
Others126 %Glycogen synthase kinase-3 alphaP49840
Others107 %Interleukin-1 receptor-associated kinase 4Q9NWZ3
Others114 %Tyrosine-protein kinase LCKP06239
Others71 %Dual specificity mitogen-activated protein kinase kinase 7O14733
Others78 %Myosin light chain kinase, smooth muscleQ15746
Others85 %Hepatocyte growth factor receptorP08581
Others65 %ALK tyrosine kinase receptorQ9UM73
Others132 %Activin receptor type-1BP36896
Others93 %Tyrosine-protein kinase BTKQ06187
Others115 %Tyrosine-protein kinase CSKP41240
Others95 %Tyrosine-protein kinase CSKP41240
Others102 %Serine/threonine-protein kinase 17AQ9UEE5
Others77 %Serine/threonine-protein kinase 17AQ9UEE5
Others126 %Ephrin type-B receptor 3P54753
Others133 %Ephrin type-B receptor 3P54753
Others121 %Tyrosine-protein kinase FESP07332
Others103 %Glycogen synthase kinase-3 alphaP49840
Others97 %Glycogen synthase kinase-3 betaP49841
Others83 %Interleukin-1 receptor-associated kinase 4Q9NWZ3
Others130 %Insulin receptor-related proteinP14616
Others107 %Tyrosine-protein kinase LCKP06239
Others80 %Tyrosine-protein kinase LCKP06239
Others107 %Myosin light chain kinase, smooth muscleQ15746
Others101 %MAP kinase signal-integrating kinase 2Q9HBH9
Others82 %MAP kinase signal-integrating kinase 2Q9HBH9
Others94 %Activin receptor type-1BP36896
Others102 %Tyrosine-protein kinase BTKQ06187
Others114 %Tyrosine-protein kinase BLKP51451
Others109 %CaM kinase I alphaQ14012
Others107 %Dual-specificity tyrosine-phosphorylation regulated kinase 2Q92630
Others94 %Ephrin type-B receptor 4P54760
Others76 %Tyrosine-protein kinase FESP07332
Others83 %Glycogen synthase kinase-3 betaP49841
Others76 %Insulin receptor-related proteinP14616
Others79 %Tyrosine-protein kinase LCKP06239
Others101 %Mitogen-activated protein kinase kinase kinase 9P80192
Others114 %Muscle, skeletal receptor tyrosine protein kinaseO15146
Others90 %Tyrosine-protein kinase BLKP51451
Others86 %Serine/threonine-protein kinase Chk1O14757
Others86 %CaM kinase I alphaQ14012
Others80 %CaM kinase II betaQ13554
Others96 %Dual-specificity tyrosine-phosphorylation regulated kinase 2Q92630
Others117 %Epidermal growth factor receptor erbB1P00533
Others119 %Ephrin type-B receptor 4P54760
Others116 %Tyrosine-protein kinase FGRP09769
Others77 %Tyrosine-protein kinase FGRP09769
Others95 %Homeodomain-interacting protein kinase 1Q86Z02
Others103 %Homeodomain-interacting protein kinase 1Q86Z02
Others99 %Tyrosine-protein kinase ITK/TSKQ08881
Others91 %Tyrosine-protein kinase ITK/TSKQ08881
Others83 %Tyrosine-protein kinase LynP07948
Others65 %Tyrosine-protein kinase LynP07948
Others81 %Mitogen-activated protein kinase kinase kinase 9P80192
Others85 %Serine/threonine-protein kinase MRCK-AQ5VT25
Others95 %Muscle, skeletal receptor tyrosine protein kinaseO15146
Others104 %Serine/threonine-protein kinase Nek11Q8NG66
Others89 %Tyrosine-protein kinase BMXP51813
Others79 %Tyrosine-protein kinase BMXP51813
Others99 %Serine/threonine-protein kinase Chk1O14757
Others55 %CaM kinase II betaQ13554
Others104 %Epidermal growth factor receptor erbB1P00533
Others96 %Receptor protein-tyrosine kinase erbB-4Q15303
Others79 %Receptor protein-tyrosine kinase erbB-4Q15303
Others96 %Vascular endothelial growth factor receptor 1P17948
Others102 %Homeodomain-interacting protein kinase 2Q9H2X6
Others80 %Tyrosine-protein kinase JAK2O60674
Others104 %MAP kinase ERK1P27361
Others84 %Serine/threonine-protein kinase MRCK-AQ5VT25
Others113 %Serine/threonine-protein kinase Nek11Q8NG66
Others107 %NUAK family SNF1-like kinase 1O60285
Others47 %BR serine/threonine-protein kinase 1Q8TDC3
Others73 %Serine/threonine-protein kinase Chk2O96017
Others90 %Serine/threonine-protein kinase Chk2O96017
Others101 %CaM kinase II gammaQ13555
Others70 %CaM kinase II gammaQ13555
Others94 %Ephrin type-A receptor 1P21709
Others106 %Ephrin type-A receptor 1P21709
Others140 %Focal adhesion kinase 1Q05397
Others47 %Vascular endothelial growth factor receptor 1P17948
Others92 %Tyrosine-protein kinase receptor FLT3P36888
Others86 %Homeodomain-interacting protein kinase 2Q9H2X6
Others101 %Homeodomain-interacting protein kinase 3Q9H422
Others121 %Tyrosine-protein kinase JAK2O60674
Others91 %Tyrosine-protein kinase JAK3P52333
Others81 %MAP kinase ERK1P27361
Others112 %MAP kinase ERK2P28482
Others90 %Serine/threonine-protein kinase MRCK betaQ9Y5S2
Others81 %Serine/threonine-protein kinase MRCK betaQ9Y5S2
Others76 %Serine/threonine-protein kinase NEK2P51955
Others68 %Serine/threonine-protein kinase NEK2P51955
Others94 %NUAK family SNF1-like kinase 1O60285
Others117 %Mitogen-activated protein kinase kinase kinase 5Q99683
Others48 %BR serine/threonine-protein kinase 1Q8TDC3
Others108 %BR serine/threonine-protein kinase 2Q8IWQ3
Others80 %Casein kinase I gamma 1Q9HCP0
Others108 %CaM kinase II deltaQ13557
Others115 %Ephrin type-A receptor 2P29317
Others93 %Focal adhesion kinase 1Q05397
Others85 %Fibroblast growth factor receptor 1P11362
Others75 %Tyrosine-protein kinase receptor FLT3P36888
Others93 %Homeodomain-interacting protein kinase 3Q9H422
Others67 %Tyrosine-protein kinase JAK3P52333
Others97 %MAP kinase ERK2P28482
Others130 %Ribosomal protein S6 kinase alpha 5O75582
Others110 %Serine/threonine-protein kinase Nek3P51956
Others107 %Mitogen-activated protein kinase kinase kinase 5Q99683
Others67 %BR serine/threonine-protein kinase 2Q8IWQ3
Others71 %Casein kinase I gamma 1Q9HCP0
Others92 %Casein kinase I gamma 2P78368
Others85 %CaM kinase II deltaQ13557
Others114 %CaM kinase IVQ16566
Others100 %Ephrin type-A receptor 2P29317
Others115 %Ephrin type-A receptor 3P29320
Others44 %Fibroblast growth factor receptor 1P11362
Others85 %Vascular endothelial growth factor receptor 3P35916
Others62 %Vascular endothelial growth factor receptor 3P35916
Others109 %Serine/threonine-protein kinase haspinQ8TF76
Others69 %Serine/threonine-protein kinase haspinQ8TF76
Others100 %c-Jun N-terminal kinase 1P45983
Others64 %c-Jun N-terminal kinase 1P45983
Others94 %MAP kinase-activated protein kinase 2P49137
Others94 %MAP kinase-activated protein kinase 2P49137
Others112 %Ribosomal protein S6 kinase alpha 5O75582
Others105 %Ribosomal protein S6 kinase alpha 4O75676
Others60 %Serine/threonine-protein kinase Nek3P51956
Others98 %Serine/threonine-protein kinase NEK6Q9HC98
Others85 %Tyrosine-protein kinase ABLP00519
Others97 %Tyrosine-protein kinase ABLP00519
Others87 %Casein kinase I gamma 2P78368
Others69 %CaM kinase IVQ16566
Others92 %Ephrin type-A receptor 3P29320
Others105 %Fibroblast growth factor receptor 2P21802
Others98 %Fibroblast growth factor receptor 2P21802
Others87 %Macrophage colony stimulating factor receptorP07333
Others92 %Tyrosine-protein kinase HCKP08631
Others82 %Insulin-like growth factor I receptorP08069
Others112 %c-Jun N-terminal kinase 2P45984
Others99 %MAP kinase-activated protein kinase 3Q16644
Others94 %Ribosomal protein S6 kinase alpha 4O75676
Others68 %Serine/threonine-protein kinase NEK6Q9HC98
Others92 %Tyrosine-protein kinase ABL2P42684
Others101 %Casein kinase I isoform gamma-3Q9Y6M4
Others72 %Casein kinase I isoform gamma-3Q9Y6M4
Others106 %CaM kinase I deltaQ8IU85
Others75 %CaM kinase I deltaQ8IU85
Others113 %Ephrin type-A receptor 4P54764
Others102 %Ephrin type-A receptor 4P54764
Others102 %Fibroblast growth factor receptor 3P22607
Others74 %Macrophage colony stimulating factor receptorP07333
Others92 %Tyrosine-protein kinase FYNP06241
Others60 %Tyrosine-protein kinase HCKP08631
Others95 %Tyrosine-protein kinase HCKP08631
Others97 %Inhibitor of nuclear factor kappa B kinase alpha subunitO15111
Others92 %c-Jun N-terminal kinase 2P45984
Others81 %c-Jun N-terminal kinase 3P53779
Others53 %MAP kinase-activated protein kinase 3Q16644
Others98 %Serine/threonine-protein kinase MARK1Q9P0L2
Others98 %cAMP-dependent protein kinase alpha-catalytic subunitP17612
Others90 %Protein kinase C thetaQ04759
Others88 %Serine/threonine-protein kinase PIM2Q9P1W9
Others100 %Serine/threonine-protein kinase PIM3Q86V86
Others79 %Tyrosine-protein kinase receptor TYRO3Q06418
Others108 %Ribosomal protein S6 kinase alpha 1Q15418
Others97 %Serine/threonine-protein kinase SIK1P57059
Others92 %Serine/threonine-protein kinase tousled-like 2Q86UE8
Others117 %Serine/threonine-protein kinase WNK3Q9BYP7
Others84 %Serine/threonine-protein kinase WNK3Q9BYP7
Others73 %cAMP-dependent protein kinase alpha-catalytic subunitP17612
Others98 %Serine/threonine-protein kinase AKTP31749
Others66 %Protein kinase C thetaQ04759
Others98 %Protein kinase C iotaP41743
Others95 %Serine/threonine-protein kinase PIM3Q86V86
Others92 %Ribosomal protein S6 kinase alpha 1Q15418
Others107 %Serine/threonine-protein kinase SRPK1Q96SB4
Others98 %Serine/threonine-protein kinase SRPK1Q96SB4
Others101 %Testis-specific serine/threonine-protein kinase 1Q9BXA7
Others105 %Testis-specific serine/threonine-protein kinase 1Q9BXA7
Others105 %Tyrosine-protein kinase YESP07947
Others110 %Serine/threonine-protein kinase AKTP31749
Others81 %Protein kinase C iotaP41743
Others108 %Serine/threonine-protein kinase PLK1P53350
Others75 %Serine/threonine-protein kinase PLK1P53350
Others115 %Ribosomal protein S6 kinase alpha 3P51812
Others91 %Ribosomal protein S6 kinase alpha 3P51812
Others96 %Serine/threonine-protein kinase SRPK2P78362
Others102 %Testis-specific serine/threonine-protein kinase 2Q96PF2
Others84 %Tyrosine-protein kinase YESP07947
Others119 %Tyrosine-protein kinase ZAP-70P43403
Others90 %Serine/threonine-protein kinase AKT2P31751
Others53 %Serine/threonine-protein kinase AKT2P31751
Others110 %Protein kinase C muQ15139
Others61 %Protein kinase C muQ15139
Others96 %Serine/threonine-protein kinase PLK3Q9H4B4
Others104 %Ribosomal protein S6 kinase alpha 2Q15349
Others96 %Serine/threonine-protein kinase SRPK2P78362
Others97 %Serine/threonine-protein kinase 33Q9BYT3
Others108 %Testis-specific serine/threonine-protein kinase 2Q96PF2
Others86 %Tyrosine-protein kinase TECP42680
Others95 %Tyrosine-protein kinase ZAP-70P43403
Others82 %Serine/threonine-protein kinase AKT3Q9Y243
Others101 %Serine/threonine-protein kinase D2Q9BZL6
Others77 %Serine/threonine-protein kinase PLK3Q9H4B4
Others104 %Serine/threonine-protein kinase PRKXP51817
Others93 %Ribosomal protein S6 kinase alpha 2Q15349
Others97 %Ribosomal protein S6 kinase alpha 6Q9UK32
Others92 %Serine/threonine-protein kinase 33Q9BYT3
Others66 %Tyrosine-protein kinase TECP42680
Others94 %Death-associated protein kinase 3O43293
Others115 %Death-associated protein kinase 3O43293
Others103 %Serine/threonine-protein kinase PAK 4O96013
Others63 %Serine/threonine-protein kinase AKT3Q9Y243
Others110 %Protein kinase C alphaP17252
Others114 %Serine/threonine-protein kinase D2Q9BZL6
Others81 %Serine/threonine-protein kinase PRKXP51817
Others103 %Ribosomal protein S6 kinase alpha 6Q9UK32
Others103 %Serine/threonine-protein kinase PLK2Q9NYY3
Others71 %Serine/threonine-protein kinase PLK2Q9NYY3
Others12 %Tyrosine-protein kinase TIE-2Q02763
Others3 %Tyrosine-protein kinase TIE-2Q02763
Others101 %Serine/threonine-protein kinase RAFP04049
Others100 %Serine/threonine-protein kinase PAK 4O96013
Others101 %Serine/threonine-protein kinase PAK7Q9P286
Others100 %Protein kinase C alphaP17252
Others110 %cGMP-dependent protein kinase 1 betaQ13976
Others92 %cGMP-dependent protein kinase 1 betaQ13976
Others133 %Protein tyrosine kinase 2 betaQ14289
Others89 %Protein tyrosine kinase 2 betaQ14289
Others106 %MAP kinase p38 alphaQ16539
Others115 %MAP kinase p38 alphaQ16539
Others132 %Tyrosine-protein kinase SYKP43405
Others113 %Nerve growth factor receptor Trk-AP04629
Others100 %Serine/threonine-protein kinase RAFP04049
Others123 %Stem cell growth factor receptorP10721
Others87 %Serine/threonine-protein kinase PAK7Q9P286
Others110 %Protein kinase C betaP05771
Others98 %Protein kinase C betaP05771
Others92 %cGMP-dependent protein kinase 1 betaQ13976
Others96 %Serine/threonine-protein kinase RIPK2O43353
Others107 %MAP kinase p38 betaQ15759
Others82 %Tyrosine-protein kinase SYKP43405
Others92 %Mitogen-activated protein kinase kinase kinase 7O43318
Others108 %Nerve growth factor receptor Trk-AP04629
Others106 %Neurotrophic tyrosine kinase receptor type 2Q16620
Others95 %Stem cell growth factor receptorP10721
Others99 %Serine/threonine-protein kinase PAK6Q9NQU5
Others61 %Serine/threonine-protein kinase PAK6Q9NQU5
Others87 %Protein kinase C betaP05771
Others87 %cGMP-dependent protein kinase 1 betaQ13976
Others84 %MAP kinase-activated protein kinase 5Q8IW41
Others88 %Serine/threonine-protein kinase RIPK2O43353
Others110 %Rho-associated protein kinase 1Q13464
Others105 %MAP kinase p38 betaQ15759
Others105 %MAP kinase p38 gammaP53778
Others94 %Mitogen-activated protein kinase kinase kinase 7O43318
Others81 %Neurotrophic tyrosine kinase receptor type 2Q16620
Others74 %Tyrosine-protein kinase SRCP12931
Others69 %Tyrosine-protein kinase SRCP12931
Others90 %MAP/microtubule affinity-regulating kinase 2Q7KZI7
Others103 %Protein kinase C betaP05771
Others97 %Protein kinase C gammaP05129
Others52 %MAP kinase-activated protein kinase 5Q8IW41
Others120 %Rho-associated protein kinase 1Q13464
Others94 %MAP kinase p38 gammaP53778
Others107 %Serine/threonine-protein kinase TAO1Q7L7X3
Others87 %Serine/threonine-protein kinase TAO1Q7L7X3
Others94 %Tyrosine-protein kinase TXKP42681
Others59 %Tyrosine-protein kinase TXKP42681
Others101 %Serine/threonine-protein kinase EEF2KO00418
Others108 %MAP/microtubule affinity-regulating kinase 2Q7KZI7
Others101 %Protein kinase C gammaP05129
Others101 %Protein kinase N2Q16513
Others92 %Protein kinase N2Q16513
Others96 %Rho-associated protein kinase 2O75116
Others82 %Rho-associated protein kinase 2O75116
Others112 %MAP kinase p38 deltaO15264
Others105 %Serine/threonine-protein kinase TAO2Q9UL54
Others104 %Serine/threonine-protein kinase ULK2Q8IYT8
Others94 %Serine/threonine-protein kinase EEF2KO00418
Others107 %Serine/threonine-protein kinase mTORP42345
Others70 %PAS domain-containing serine/threonine-protein kinaseQ96RG2
Others61 %PAS domain-containing serine/threonine-protein kinaseQ96RG2
Others104 %Protein kinase C deltaQ05655
Others103 %Protein kinase C deltaQ05655
Others94 %Tyrosine-protein kinase FRKP42685
Others86 %Tyrosine-protein kinase receptor RETP07949
Others97 %MAP kinase p38 deltaO15264
Others102 %Serine/threonine-protein kinase Sgk1O00141
Others93 %Serine/threonine-protein kinase TAO2Q9UL54
Others99 %Serine/threonine-protein kinase TAO3Q9H2K8
Others94 %Serine/threonine-protein kinase ULK2Q8IYT8
Others107 %Serine/threonine-protein kinase ULK3Q6PHR2
Others88 %Serine/threonine-protein kinase mTORP42345
Others113 %Platelet-derived growth factor receptor alphaP16234
Others88 %Protein kinase C epsilonQ02156
Others69 %Tyrosine-protein kinase FRKP42685
Others111 %Phosphorylase kinase gamma subunit 2P15735
Others106 %Tyrosine-protein kinase receptor RETP07949
Others86 %Macrophage-stimulating protein receptorQ04912
Others85 %Serine/threonine-protein kinase Sgk1O00141
Others90 %Serine/threonine-protein kinase TAO3Q9H2K8
Others96 %Serine/threonine-protein kinase ULK3Q6PHR2
Others103 %Platelet-derived growth factor receptor alphaP16234
Others108 %Platelet-derived growth factor receptor betaP09619
Others78 %Protein kinase C epsilonQ02156
Others103 %Protein kinase C zetaQ05513
Others96 %Phosphorylase kinase gamma subunit 2P15735
Others75 %Macrophage-stimulating protein receptorQ04912
Others130 %Serine/threonine-protein kinase Sgk2Q9HBY8
Others65 %Serine/threonine-protein kinase Sgk2Q9HBY8
Others81 %Serine/threonine-protein kinase TBK1Q9UHD2
Others65 %Serine/threonine-protein kinase TBK1Q9UHD2
Others110 %Serine/threonine-protein kinase VRK2Q86Y07
Others91 %Serine/threonine-protein kinase VRK2Q86Y07
Others130 %Ribosomal protein S6 kinase 1P23443
Others108 %Platelet-derived growth factor receptor betaP09619
Others75 %Protein kinase C zetaQ05513
Others93 %Serine/threonine-protein kinase PIM1P11309
Others93 %Serine/threonine-protein kinase PIM1P11309
Others97 %Proto-oncogene tyrosine-protein kinase ROSP08922
Others104 %Proto-oncogene tyrosine-protein kinase ROSP08922
Others102 %Serine/threonine-protein kinase Sgk3Q96BR1
Others82 %TGF-beta receptor type IP36897
Others114 %Serine/threonine-protein kinase WNK2Q9Y3S1
Others63 %Ribosomal protein S6 kinase 1P23443
Others106 %3-phosphoinositide dependent protein kinase-1O15530
Others110 %3-phosphoinositide dependent protein kinase-1O15530
Others112 %Protein kinase C etaP24723
Others86 %Protein kinase C etaP24723
Others86 %Serine/threonine-protein kinase PIM2Q9P1W9
Others89 %Tyrosine-protein kinase receptor TYRO3Q06418
Others79 %Serine/threonine-protein kinase Sgk3Q96BR1
Others92 %Serine/threonine-protein kinase SIK1P57059
Others89 %TGF-beta receptor type IP36897
Others95 %Serine/threonine-protein kinase tousled-like 2Q86UE8
Others76 %Serine/threonine-protein kinase WNK2Q9Y3S1
IC501280000 nMDOPA decarboxylaseP20711