Tryptamine

Representations & DB's id
ChEBI:	CHEBI:16765
ChEMBL:	CHEMBL6640
PubChem:	1150
IUPAC:	2-(1H-indol-3-yl)ethanamine
Standard InChI:	InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2
Standard InChI Key:	APJYDQYYACXCRM-UHFFFAOYSA-N
SMILES:	NCCc1c[nH]c2c1cccc2

Molecular propeties
AlogP:	1.67
Hydrogen bonds acceptors:	1
Hydrogen bonds donors:	2
Rotatable bonds:	2
Number of rings:	2
Molecular Weight:	160.1
Topological polar surface area:	41.8
Number of aromatic rings:	2
Fsp3:	0.2
Number of carbons:	10

Plant sources

Activity Type	Activity Value	Target Name	UniProt ID
Potency	12589.3 nM	Nuclear factor NF-kappa-B p105 subunit	P19838
Potency	12589.3 nM	Nuclear factor NF-kappa-B p105 subunit	P19838
Potency	39810.7 nM	Cytochrome P450 3A4	P08684
Potency	31622.8 nM	Cytochrome P450 2D6	P10635
Potency	39810.7 nM	Cytochrome P450 3A4	P08684
Potency	10322.5 nM	Nuclear factor erythroid 2-related factor 2	Q16236
Potency	50118.7 nM	Lysine-specific demethylase 4A	O75164
Potency	1299.5 nM	Dopamine D1 receptor	P21728
Potency	32629.4 nM	ATPase family AAA domain-containing protein 5	Q96QE3
Potency	25929 nM	Dopamine D1 receptor	P21728
Potency	6513.1 nM	Geminin	O75496
Ki	70 nM	Serotonin 6 (5-HT6) receptor	P50406
IC50	770 nM	Myeloperoxidase	P05164
EC50	7.36 nM	Serotonin 2a (5-HT2a) receptor	P28223
Ki	1700 nM	Cytochrome P450 2A6	P11509
Ki	16000 nM	Cytochrome P450 2A13	Q16696
Kd	2300 nM	Cytochrome P450 2A6	P11509
Kd	5200 nM	Cytochrome P450 2A13	Q16696
Others	0 %	Indoleamine 2,3-dioxygenase	P14902
Ki	160000 nM	Indoleamine 2,3-dioxygenase	P14902