Phyto4Health

2-Phenylphenol

Representations & DB's id
ChEBI: CHEBI:17043
ChEMBL: CHEMBL108829
PubChem: 7017
IUPAC: 2-phenylphenol
Standard InChI: InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
Standard InChI Key: LLEMOWNGBBNAJR-UHFFFAOYSA-N
SMILES: Oc1ccccc1c1ccccc1

Molecular propeties
AlogP: 3.06
Hydrogen bonds acceptors: 1
Hydrogen bonds donors: 1
Rotatable bonds: 1
Number of rings: 2
Molecular Weight: 170.07
Topological polar surface area: 20.2
Number of aromatic rings: 2
Fsp3: 0
Number of carbons: 12

Plant sources

Part of plant Plant name Ref.
PlantVaccinium vitis-idaea

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Kd2700000 nMApoptosis regulator Bcl-XQ07817
Potency31622.8 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency17782.8 nMAldehyde dehydrogenase 1A1P00352
Potency8912.5 nM15-hydroxyprostaglandin dehydrogenase [NAD+]P15428
Others14 pm/min/mgUDP-glucuronosyltransferase 1-1P22309
Others4 pm/min/mgUDP-glucuronosyltransferase 1-10Q9HAW8
Others0 pm/min/mgUDP-glucuronosyltransferase 1-10Q9HAW8
Others94 pm/min/mgUDP-glucuronosyltransferase 1-3P35503
Others5 pm/min/mgUDP-glucuronosyltransferase 1A4P22310
Others12 pm/min/mgUDP-glucuronosyltransferase 1-7Q9HAW7
Others290 pm/min/mgUDP-glucuronosyltransferase 1-8Q9HAW9
Others305 pm/min/mgUDP-glucuronosyltransferase 1-8Q9HAW9
Others130 pm/min/mgUDP-glucuronosyltransferase 2A1Q9Y4X1
Others0 pm/min/mgUDP-glucuronosyltransferase 2B15P54855
Others7 pm/min/mgUDP-glucuronosyltransferase 2B17O75795
Others5 pm/min/mgUDP-glucuronosyltransferase 2B17O75795
Potency251188.6 nMNuclear factor NF-kappa-B p105 subunitP19838
Potency446683.6 nMCellular tumor antigen p53P04637
Potency30637.9 nMNuclear factor erythroid 2-related factor 2Q16236
Potency42163.2 nMNuclear factor erythroid 2-related factor 2Q16236
Potency398107.2 nMNuclear factor erythroid 2-related factor 2Q16236
Potency251188.6 nMPeroxisome proliferator-activated receptor alphaQ07869
Others19 %Cytosolic purine 5'-nucleotidaseP49902