2,6-Dimethoxyquinone

Representations & DB's id
ChEBI:	None
ChEMBL:	CHEMBL448515
PubChem:	68262
IUPAC:	2,6-dimethoxycyclohexa-2,5-diene-1,4-dione
Standard InChI:	InChI=1S/C8H8O4/c1-11-6-3-5(9)4-7(12-2)8(6)10/h3-4H,1-2H3
Standard InChI Key:	OLBNOBQOQZRLMP-UHFFFAOYSA-N
SMILES:	COC1=CC(=O)C=C(C1=O)OC

Molecular propeties
AlogP:	0.2
Hydrogen bonds acceptors:	4
Hydrogen bonds donors:	0
Rotatable bonds:	2
Number of rings:	1
Molecular Weight:	168.04
Topological polar surface area:	52.6
Number of aromatic rings:	0
Fsp3:	0.25
Number of carbons:	8

Plant sources

Part of plant	Plant name	Ref.
Plant	Valeriana officinalis
Plant	Adonis vernalis

In vitro data

Activity Type	Activity Value	Target Name	UniProt ID	Ref.
Potency	17782.8 nM	Lysine-specific demethylase 4D-like	B2RXH2
Potency	25118.9 nM	Survival motor neuron protein	Q16637
Potency	10000 nM	Microtubule-associated protein tau	P10636
Potency	22387.2 nM	Microtubule-associated protein tau	P10636
Potency	7943.3 nM	Ubiquitin carboxyl-terminal hydrolase 2	O75604
Potency	28183.8 nM	MAP kinase ERK2	P28482
Potency	15848.9 nM	Cellular tumor antigen p53	P04637
Potency	31622.8 nM	Cellular tumor antigen p53	P04637
Potency	25118.9 nM	Cytochrome P450 3A4	P08684
Potency	25118.9 nM	Cytochrome P450 3A4	P08684
Potency	29092.9 nM	Nuclear factor erythroid 2-related factor 2	Q16236
IC50	2490 nM	Putative hexokinase HKDC1	Q2TB90
IC50	3540 nM	Putative hexokinase HKDC1	Q2TB90
Potency	5173.5 nM	Geminin	O75496
Potency	8912.5 nM	Ataxin-2	Q99700
Potency	28183.8 nM	Glucagon-like peptide 1 receptor	P43220
Potency	44668.4 nM	Werner syndrome ATP-dependent helicase	Q14191