Phyto4Health

Arginine

Representations & DB's id
ChEBI: CHEBI:16467
ChEMBL: CHEMBL1485
PubChem: 6322
IUPAC: (2S)-2-amino-5-(diaminomethylideneazaniumyl)pentanoate
Standard InChI: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
Standard InChI Key: ODKSFYDXXFIFQN-BYPYZUCNSA-N
SMILES: NC(=N)NCCC[C@@H](C(=O)O)N

Molecular propeties
AlogP: -1.34
Hydrogen bonds acceptors: 3
Hydrogen bonds donors: 5
Rotatable bonds: 5
Number of rings: 0
Molecular Weight: 174.11
Topological polar surface area: 128
Number of aromatic rings: 0
Fsp3: 0.667
Number of carbons: 6

Plant sources

Part of plant Plant name Ref.
PlantBrassica juncea
PlantPrunus dulcis
PlantOenanthe phellandrium
PlantTrigonella foenum-graecum
PlantPolemonium caeruleum

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
Others3.71 %Tryptase beta-1Q15661
Potency251.2 nMNuclear factor NF-kappa-B p105 subunitP19838
Potency6309.6 nMThyroid stimulating hormone receptorP16473
Potency10000 nMCytochrome P450 2C19P33261
Potency251.2 nMNuclear factor NF-kappa-B p105 subunitP19838
Potency39810.7 nMDNA-(apurinic or apyrimidinic site) lyaseP27695
Potency5011.9 nMAlpha-galactosidase AP06280
Potency25118.9 nMHistone-lysine N-methyltransferase, H3 lysine-9 specific 3Q96KQ7
Potency10000 nMHistone-lysine N-methyltransferase, H3 lysine-9 specific 3Q96KQ7
Potency39810.7 nMChromobox protein homolog 1P83916
Others49 %L-type amino acid transporter 1Q01650
Others0.8 fmol/minL-type amino acid transporter 1Q01650