Phyto4Health

Tricetin

Representations & DB's id
ChEBI: CHEBI:507499
ChEMBL: CHEMBL247484
PubChem: 5281701
IUPAC: 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
Standard InChI: InChI=1S/C15H10O7/c16-7-3-8(17)14-9(18)5-12(22-13(14)4-7)6-1-10(19)15(21)11(20)2-6/h1-5,16-17,19-21H
Standard InChI Key: ARSRJFRKVXALTF-UHFFFAOYSA-N
SMILES: Oc1cc(O)c2c(c1)oc(cc2=O)c1cc(O)c(c(c1)O)O

Molecular propeties
AlogP: 1.99
Hydrogen bonds acceptors: 7
Hydrogen bonds donors: 5
Rotatable bonds: 1
Number of rings: 3
Molecular Weight: 302.04
Topological polar surface area: 127
Number of aromatic rings: 3
Fsp3: 0
Number of carbons: 15

Plant sources

Part of plant Plant name Ref.
PlantPunica granatum
PlantPunica granatum
PlantEucalyptus maideni

In vitro data

Activity Type Activity Value Target Name UniProt ID Ref.
IC50130000 nMSialidase 2Q9Y3R4
Potency707.9 nMATP-dependent DNA helicase Q1P46063
Potency42128.5 nMGalactokinaseP51570
Potency12589.3 nMEndoplasmic reticulum-associated amyloid beta-peptide-binding proteinQ99714
Potency10000 nMLysine-specific demethylase 4D-likeB2RXH2
Potency25118.9 nMHemoglobin beta chainP68871
Potency7943.3 nMMicrotubule-associated protein tauP10636
Potency39810.7 nMAldehyde dehydrogenase 1A1P00352
Potency2511.9 nMArachidonate 15-lipoxygenaseP16050
Potency17782.8 nM15-hydroxyprostaglandin dehydrogenase [NAD+]P15428
Potency25118.9 nMBloom syndrome proteinP54132
Potency19952.6 nMCytochrome P450 3A4P08684
Potency19952.6 nMCytochrome P450 3A4P08684
Potency12589.3 nMArachidonate 15-lipoxygenase, type IIO15296
IC5017500 nMReceptor-type tyrosine-protein phosphatase SQ13332
Others83.9 %Receptor-type tyrosine-protein phosphatase SQ13332