3-[5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxochromen-8-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One

Representations & DB's id
ChEBI:	None
ChEMBL:	CHEMBL515252
PubChem:	10414856
IUPAC:	3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Standard InChI:	InChI=1S/C30H18O10/c31-15-5-1-13(2-6-15)22-12-21(37)24-19(35)11-20(36)26(30(24)39-22)27-28(38)25-18(34)9-17(33)10-23(25)40-29(27)14-3-7-16(32)8-4-14/h1-12,31-36H
Standard InChI Key:	IQAMTZLKUHMPPE-UHFFFAOYSA-N
SMILES:	Oc1ccc(cc1)c1cc(=O)c2c(o1)c(c(cc2O)O)c1c(oc2c(c1=O)c(O)cc(c2)O)c1ccc(cc1)O

Molecular propeties
AlogP:	5.13
Hydrogen bonds acceptors:	10
Hydrogen bonds donors:	6
Rotatable bonds:	3
Number of rings:	6
Molecular Weight:	538.09
Topological polar surface area:	174
Number of aromatic rings:	6
Fsp3:	0
Number of carbons:	30

Plant sources

Activity Type	Activity Value	Target Name	UniProt ID
Potency	12589.3 nM	ATP-dependent DNA helicase Q1	P46063
Potency	35481.3 nM	Lysine-specific demethylase 4D-like	B2RXH2
Potency	1995.3 nM	DNA-(apurinic or apyrimidinic site) lyase	P27695
Potency	15848.9 nM	Microtubule-associated protein tau	P10636
Potency	7943.3 nM	Pyruvate kinase isozymes M1/M2	P14618
Potency	7079.5 nM	Microtubule-associated protein tau	P10636
IC50	2725.54 nM	Induced myeloid leukemia cell differentiation protein Mcl-1	Q07820
Potency	7943.3 nM	Pyruvate kinase isozymes M1/M2	P14618
Potency	12589.3 nM	Bloom syndrome protein	P54132
Potency	3162.3 nM	DNA polymerase beta	P06746
Potency	17782.8 nM	Beta-glucocerebrosidase	P04062
Potency	50118.7 nM	Lysine-specific demethylase 4A	O75164
Potency	28183.8 nM	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8
Potency	18356.4 nM	Geminin	O75496
IC50	66600 nM	Small ubiquitin-related modifier 1	P63165
Potency	259.3 nM	Geminin	O75496
Potency	56234.1 nM	Werner syndrome ATP-dependent helicase	Q14191
IC50	9200 nM	Small ubiquitin-related modifier 1	P63165
IC50	4500 nM	Protein-tyrosine phosphatase 1B	P18031
Ki	4600 nM	Protein-tyrosine phosphatase 1B	P18031