A Knowledge Based Approach to Drug Repurposing for Socially Important and Rare Diseases
RSF - DST Project # 16-45-02012 - INT/RUS/RSF/12

Pharmacological Targets

A knowledge base of drug targets, used for the treatment of tuberculosis, and those considered as promising in the development of new pharmaceuticals. All pharmacological targets are differentiated into three categories: the targets of approved drugs (Launched); drugs targets studied in clinical trials (Clinical); targets of pharmacological substances investigated in preclinical studies (Preclinical). Relevant information indirectly characterizing the degree of reliability of the association of a particular target with the disease in question was included in our database.


One may browse the records in the database or search for a particular drug target using target name as a query.


Pharmacological targets are associated with links on the appropriate information in UniProt, KEGG and PDB.


Loading .. Please wait

Target's name UniProt PDB Kegg Pharmacotheraputic application
Launched Clinical Preclinical
Target's name UniProt PDB Kegg Pharmacotheraputic application
Launched Clinical Preclinical
Phosphotyrosine protein phosphatase PtpBA0A0T9ME74
Tuberculosis
1-deoxy-D-xylulose 5-phosphate reductoisomeraseQ8IKG4
MalariaTuberculosis
16S Ribosomal protein
Tuberculosis
30S Ribosomal protein
TuberculosisCancer
Acetolactate synthase isozyme 2 large subunitP00892
Tuberculosis
Acetolactate synthase large subunit IlvBP9WG41
Tuberculosis
Acetyl-CoA Carboxylases (ACC) (nonspecified subtype)
Tuberculosis
Malaria
Diabetes
Cancer
Adenosine kinaseP9WID5
Tuberculosis
Adenylate cyclaseP9WQ35
Tuberculosis
Alanine Racemase
Tuberculosis
alpha-Mannosidase (nonspecified subtype)P14780
Diabetes
Cancer
Tuberculosis
Amine oxidase [flavin-containing] AP21397
Diabetes
Tuberculosis
Malaria
Cancer
Leishmaniasis
Epilepsy
Amine oxidase [flavin-containing] BP27338
Malaria
Tuberculosis
Diabetes
Epilepsy
Cancer
ATP-Binding Cassette (ABC) Transporter (nonspecified subtype)P08581
Leishmaniasis
Tuberculosis
Cancer
ATP-Dependent Clp Protease ClpP1P2
Tuberculosis
Beta-lactamase (nonspecified subtype)
TuberculosisMalaria
Bifunctional protein GlmU
Tuberculosis
Bifunctional salicyl-AMP ligase/salicyl-S-ArCP synthetaseP71716
Tuberculosis
C-X-C chemokine receptor type 4 (isoform a)P61073
CancerDiabetes
Tuberculosis
C-X-C chemokine receptor type 4 (isoform b)P61073
CancerDiabetes
Tuberculosis
Carbonic Anhydrase (nonspecified subtype)
Tuberculosis
Cancer
Epilepsy
Malaria
Carbonic anhydrase 1P00915
Cancer
Tuberculosis
Epilepsy
Diabetes
Carbonic anhydrase 2P00918
Diabetes
Cancer
Epilepsy
Tuberculosis
Carbonic anhydrase 4P22748
Tuberculosis
Carbonic anhydrase 6P23280
EpilepsyTuberculosis
Caspase-3 (isoform alpha)P42574
CancerEpilepsy
Diabetes
Tuberculosis
Malaria
CD44 antigen (isoform 1)P16070
CancerTuberculosis
CD44 antigen (isoform 3)P16070
CancerTuberculosis
CD44 antigen (isoform 4)P16070
CancerTuberculosis
CD44 antigen (isoform 5)P16070
CancerTuberculosis
CD44 antigen (isoform 6)P16070
CancerTuberculosis
Cell division protein FtsZP9WN95

Tuberculosis
cGMP-Dependent Protein Kinase (Protein Kinase G; PKG) (nonspecified subtype)
CancerTuberculosis
Corticosteroid 11-beta-dehydrogenase isozyme 2P80365
Tuberculosis
Malaria
Cancer
Diabetes
Cytochrome bc1 complex cytochrome b subunitP9WP37
Tuberculosis
Deoxythymidylate kinase (thymidylate kinase)P23919
TuberculosisCancer
Deoxyuridine 5'-triphosphate nucleotidohydrolase, putativeQ8II92
CancerTuberculosis
Malaria
Dihydrofolate reductase (DHFR) (bacterial)
Tuberculosis
DNA gyrase (bacterial)
Tuberculosis
DNA gyrase subunit AQ07702
P48354
Tuberculosis
DNA Polymerase (bacterial) (nonspecified subtype)
CancerTuberculosis
DNA Polymerase III
Tuberculosis
DNA topoisomerase IV (bacterial)
Tuberculosis
DNA-Directed DNA Polymerase
CancerTuberculosis
Diabetes
Enoyl-(acyl carrier protein) reductaseP71079
Tuberculosis
Malaria
Enoyl-(Acyl Carrier Protein) Reductase (Fabl)
Tuberculosis
Malaria
Enoyl-[acyl-carrier-protein] reductase (NADH)P9WGR0
Tuberculosis
Epoxide Hydrolase (nonspecified subtype)
CancerTuberculosis
Epilepsy
Diabetes
F0F1 ATP synthase (Mycobacterium spp.)
TuberculosisMalaria
F0F1 ATP synthase (nonspecified subtype)
TuberculosisMalaria
FAD-dependent decaprenylphosphoryl-beta-D-ribofuranose 2-oxidaseP9WJF1
Tuberculosis
Fatty acid synthase (bacterial)
TuberculosisCancer
Gelatinase A (isoform a)P42330
P05091
P08253
Cancer
Tuberculosis
Diabetes
Glutamate decarboxylase/Glutamate--ammonia ligaseP15104
Tuberculosis
Glycogen synthase kinase 3 betaQ02763
P10275
P49841
Cancer
Diabetes
Malaria
Leishmaniasis
Epilepsy
Tuberculosis
H+/K+-ATPaseP12821
Cancer
Diabetes
TuberculosisMalaria
Hypoxia-inducible factor 1-alpha (isoform 1)Q16665
CancerDiabetes
Malaria
Tuberculosis
Integrin alphavbeta3 (vitronectin) receptor
Tuberculosis
Cancer
Interferon (nonspecified subtype)
CancerTuberculosis
Malaria
Leishmaniasis
Interleukin-4 precursor (isoform 1)P05112
Tuberculosis
Cancer
Diabetes
Interleukin-8P10145
CancerTuberculosis
Leishmaniasis
Diabetes
Interstitial collagenase (MMP-1)P03956
Tuberculosis
Cancer
Leucine--tRNA ligaseP9WFV1
Tuberculosis
LH receptorP22888
Tuberculosis
Malaria
Lysosomal alpha-glucosidaseP10253
DiabetesCancer
Tuberculosis
Leishmaniasis
Malaria
Macrophage mannose receptor 1P22897
Tuberculosis
Metallo-beta-lactamaseE5KIY2
Tuberculosis
Methionine aminopeptidaseQ8IJP2
A0A045HTR4
Tuberculosis
Leishmaniasis
Malaria
Methionyl aminopeptidaseA0A045HTR4
Tuberculosis
Mitogen-activated protein kinase kinase kinase 5Q99683
CancerDiabetes
Tuberculosis
Monoamine oxidase (MAO) (nonspecified subtype)
CancerTuberculosisEpilepsy
Diabetes
Malaria
Mycocyclosin synthaseP9WPP7
Tuberculosis
N-formyl peptide receptor 2 (FMLP-R-I)P25090
TuberculosisCancer
Diabetes
Epilepsy
Neutrophil elastaseP08246
Tuberculosis
Cancer
Nuclear factor erythroid 2-related factor 2 (Nrf2)Q16236
CancerTuberculosisDiabetes
Epilepsy
Nuclear receptor subfamily 1 group I member 2 isoform 1O75469
Tuberculosis
Cancer
Epilepsy
Diabetes
Nuclear receptor subfamily 1 group I member 2 isoform 2O75469
Tuberculosis
Cancer
Epilepsy
Diabetes
P2X purinoceptor 7 (P2X7)Q99572
CancerTuberculosis
Diabetes
Epilepsy
Pantothenate synthetaseP9WIL5
Tuberculosis
Peptide deformylaseP96275
TuberculosisCancer
Peptide Deformylase, MitochondrialQ9HBH1
TuberculosisCancer
Peroxisome proliferative activated receptor gamma (isoform 1)P37231
Cancer
Tuberculosis
Malaria
Leishmaniasis
Epilepsy
Diabetes
Peroxisome proliferator-activated receptor delta isoform 1Q03181
DiabetesTuberculosisCancer
Peroxisome proliferator-activated receptor gamma (isoform 2)P37231
Tuberculosis
Cancer
Epilepsy
Leishmaniasis
Malaria
Diabetes
Phospho-N-Acetylmuramoyl-Pentapeptide-Transferase (Mra Y Transferase) (bacterial)
Tuberculosis
Phospholipase A2 (nonspecified subtype)
Leishmaniasis
Cancer
Diabetes
Tuberculosis
Pr55(Gag)P04591
Q77YG1
Tuberculosis
Prostaglandin G/H synthase 2 (COX-2)P35354
Tuberculosis
Cancer
EpilepsyDiabetes
Proteasome Complex
CancerTuberculosis
Diabetes
Malaria
Protein-tyrosine-phosphataseP9WIA1
Tuberculosis
Proteinase-activated receptor 1P25116
Tuberculosis
Cancer
Pyruvate dehydrogenase kinase (nonspecified subtype)
Diabetes
Cancer
Tuberculosis
RNA polymerase (bacterial)
Tuberculosis
Cancer
Salicylate synthase MbtIQ7D785
Tuberculosis
Serine/threonine-protein kinase pknBP0A5S4
Tuberculosis
Serine/threonine-protein kinase PLK1P53350
CancerTuberculosisEpilepsy
Shikimate kinase
Tuberculosis
Signal Peptidase IB (SpsB)
Tuberculosis
Signal transducer and activator of transcription 3 (isoform 1)P40763
Cancer
Diabetes
Tuberculosis
Schistosomiasis
Signal transducer and activator of transcription 3 (isoform 2)P40763
Cancer
Diabetes
Tuberculosis
Schistosomiasis
Signal transducer and activator of transcription 3 (isoform 3)P40763
Cancer
Diabetes
Tuberculosis
Schistosomiasis
Soluble epoxide hydrolase (SEH)P34913
CancerTuberculosis
Diabetes
Epilepsy
Sphingomyelin phosphodiesterase 1P17405
Tuberculosis
Diabetes
Cancer
Sterol 14-alpha demethylaseQ7Z1V1
Tuberculosis
Leishmaniasis
Cancer
Stromelysin-1 (MMP-3)P08254
Tuberculosis
Cancer
Diabetes
Telomerase reverse transcriptase (isoform 1)O14746
CancerTuberculosis
Diabetes
Thioredoxin reductase 1, cytoplasmic isoform 1Q16881
CancerTuberculosis
Malaria
Diabetes
Thioredoxin reductase 2, mitochondrial isoform 1 precursorQ9NNW7
CancerMalaria
Tuberculosis
Diabetes
Thymidylate synthase ThyXP9WG57
Tuberculosis
Toll-like receptor 2O60603
TuberculosisDiabetesCancer
Toll-like receptor 9 precursorQ9NR96
Tuberculosis
Cancer
DiabetesMalaria
Tubulin
CancerTuberculosisDiabetes
Type II NADH dehydrogenase
Tuberculosis
TyrosinaseP14679
Cancer
Tuberculosis
Diabetes
Tyrosine-protein phosphatase non-receptor type 1P18031
CancerTuberculosis
Leishmaniasis
Diabetes
Tyrosyl-tRNA synthetase (bacterial)
Tuberculosis
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialQ07973
Cancer
11beta-Hydroxysteroid Dehydrogenase (nonspecified subtype)P24385
Diabetes
Cancer
14-3-3 protein epsilonP62258
Cancer
15-hydroxyprostaglandin dehydrogenase (NAD+) (isoform 1)P15428
Cancer
15-Lipoxygenase (nonspecified subtype)P30281
Cancer
Malaria
17beta-Hydroxysteroid dehydrogenase (nonspecified subtype)P24864
Cancer
Diabetes
1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor (isoform a)O15120
Cancer
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1P19174
Cancer
26S proteasome non-ATPase regulatory subunit 14O00487
Diabetes
Cancer
3 beta-Hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (nonspecified subtype)
Cancer
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1P14060
Cancer
3',5'-Cyclic-nucleotide phosphodiesterase 10AQ9Y233
Cancer
Diabetes
Epilepsy
3-oxo-5-alpha-steroid 4-dehydrogenase 1P18405
Cancer
3-oxo-5-alpha-steroid 4-dehydrogenase 2P31213
Cancer
3-oxoacyl-(acyl-carrier protein) reductaseQ8I2S7
Cancer
Leishmaniasis
Malaria
3-phosphoinositide-dependent protein kinase 1 (isoform 1)O15530
CancerDiabetes
4-Aminobutyrate transaminase isoform 1 (GABA aminotransferase; GABA-AT)P80404
EpilepsyCancer
4F2 cell-surface antigen heavy chainP08195
Cancer
5-HT1A receptorP08908
EpilepsyCancer
5-HT1B receptorP28222
Cancer
Diabetes
5-HT2A (isoform 1)P28223
Cancer
5-HT2B receptorP41595
Malaria
Cancer
Epilepsy
5-HT2C receptorP28335
Epilepsy
Cancer
Diabetes
Malaria
5-HT4 receptor (isoform b)Q13639
Diabetes
5-HT4 Receptor (nonspecified subtype)
Diabetes
5-HT6 receptorP50406
Cancer
Diabetes
Epilepsy
5-HT7 (isoform a)P34969
DiabetesEpilepsy
5'-NucleotidaseP21589
Cancer
60 kDa heat shock protein, mitochondrialP10809
Cancer
6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3Q16875
Cancer
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4Q16877
Cancer
78 kDa Glucose-regulated proteinP11021
Cancer
8-oxo-dGTP diphosphatase/2-hydroxy-dATP diphosphatase (isoform p18)P36639
Cancer
8-oxo-dGTP diphosphatase/2-hydroxy-dATP diphosphatase (isoform p22)P36639
Cancer
Abelson tyrosine-protein kinase 2P42684
Cancer
Acetylcholine receptor subunit alpha (isoform a)P02708
Cancer
Epilepsy
Acetylcholine receptor subunit alpha (isoform b)P02708
Cancer
Epilepsy
Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype)P47211
P21217
P17931
CancerEpilepsy
Diabetes
Malaria
AcetylcholinesteraseP22303
Leishmaniasis
Cancer
Epilepsy
Diabetes
Acetyl-CoA carboxylase 1 isoform 1Q13085
Diabetes
Cancer
Acetyl-CoA carboxylase 1 isoform 4Q13085
Cancer
Diabetes
Acetyl-CoA carboxylase 2 precursorO00763
DiabetesCancer
Acetyl-coenzyme A synthetase, cytoplasmicQ9NR19
Cancer
Acidic mammalian chitinase (AMCase)Q9BZP6
Cancer
Actin (nonspecified subtype)P17931
Cancer
Activated CDC42 kinase 1 isoform 1Q07912
Cancer
Activin Receptor Type-1Q04771
Cancer
Activin receptor type-1BP36896
Cancer
Acyl-CoA desaturaseO00767
Malaria
Cancer
Diabetes
Acyl-CoA:cholesterol acyltransferase (nonspecified subtype)P17931
Cancer
Malaria
Diabetes
Acylglycerol kinase, mitochondrial precursorQ53H12
Cancer
ADAM10 endopeptidaseO14672
Cancer
ADAM28 (isoform 1)Q9UKQ2
Cancer
ADAM28 (isoform 3)Q9UKQ2
Cancer
ADAM8P78325
Cancer
Adenosine A2A receptorP29274
CancerDiabetes
Adenosine A2B receptorP29275
CancerDiabetes
Adenosine A3 receptorP33765
Cancer
Adenosine deaminase (nonspecified subtype)P17931
Cancer
Adenosine deaminaseP00813
Cancer
Adenosine kinase (isoform b)P55263
CancerEpilepsy
Adenosine receptor (nonspecified subtype)Q9UBS5
P17931
O75899
CancerDiabetes
Adenosine receptor A1P30542
Diabetes
Cancer
Epilepsy
Adenosylhomocysteinase (isoform X1)P23526
MalariaCancer
AdenosylhomocysteinaseP23526
MalariaCancer
Adenylate Cyclase (nonspecified subtype)
Cancer
Malaria
Adenylosuccinate synthetase isozyme 2P30520
Cancer
Adiponectin receptor protein 1Q96A54
Cancer
Diabetes
Adiponectin receptor protein 2Q86V24
CancerDiabetes
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38)P28907
Cancer
ADP-ribosylation factor 1P84077
Cancer
ADP-ribosylation factor 6P62330
Cancer
ADP-ribosylation factor GTPase-activating protein 1 isoform aQ8N6T3
Cancer
AdrenomedullinP35318
Cancer
Diabetes
Advanced glycosylation end product-specific receptor precursor (isoform 1)Q15109
Diabetes
Cancer
Advanced glycosylation end product-specific receptor precursor (isoform 2)Q15109
Diabetes
Cancer
Aggrecanase (nonspecified subtype)
Cancer
AGS-16
Cancer
Alcohol Dehydrogenase (nonspecified subtype)
Cancer
Alcohol dehydrogenase class-3P11766
Cancer
Aldehyde dehydrogenase, dimeric NADP-preferringP30838
Cancer
Aldehyde dehydrogenase, mitochondrial (isoform 2)P05091
Cancer
Diabetes
Aldehyde dehydrogenase, mitochondrialP05091
Cancer
Diabetes
Aldo-keto reductase family 1 member B10O60218
Cancer
Epilepsy
Diabetes
Aldo-keto reductase family 1, member C3P42330
Cancer
Diabetes
Aldose Reductase (Aldehyde reductase)P15121
DiabetesLeishmaniasis
Cancer
ALK tyrosine kinase receptor precursorQ9UM73
Cancer
alpha1-Adrenoceptor (nonspecified subtype)P14780
Cancer
Alpha1B-adrenoceptorP35368
DiabetesCancer
alpha-1D AdrenoceptorP25100
Cancer
Alpha-2,8-sialyltransferase 8BQ92186
Cancer
alpha2A-AdrenoceptorP08913
Diabetes
Cancer
alpha2-Adrenoceptor (nonspecified subtype)Q92847
P14780
Malaria
Diabetes
Epilepsy
Alpha-4 beta-2 nicotinic receptorP08253
Epilepsy
Cancer
alpha-Adrenoceptor (nonspecified subtype)P14780
P08253
Cancer
Alpha-aminoadipic semialdehyde dehydrogenaseP49419
Cancer
alpha-Amylase (nonspecified subtype)P14780
Cancer
Diabetes
Alpha-crystallin A chainP02489
Cancer
Alpha-fetoprotein precursorP02771
Cancer
Alpha-globin transcription factor CP2 (isoform 1)Q12800
Cancer
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3Q96Q83
Cancer
alpha-Secretase (nonspecified subtype)P14780
Cancer
Amiloride-sensitive cation channel 2, neuronal (isoform a)P78348
Cancer
Amine oxidase (copper-containing) 3 (VAP-1)Q16853
Diabetes
Cancer
Aminopeptidase NP15144
CancerMalaria
AMP-activated protein kinase (AMPK)Q8TDV5
Q04609
P35575
P04150
P04062
Epilepsy
Diabetes
Cancer
Leishmaniasis
Malaria
Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype)Q04609
MalariaDiabetes
Amyloid beta A4 protein precursor (isoform a)P05067
EpilepsyDiabetes
Malaria
Anandamide membrane transporter (AMT)P00390
Cancer
Androgen receptor (isoform 1)P10275
CancerDiabetes
Androgen receptor (isoform 2)P10275
CancerDiabetes
Angiopoietin 1 (isoform a)Q15389
Cancer
Angiopoietin-1 receptor (Tie-2)
Cancer
Angiopoietin-2 (isoform a)O15123
Cancer
Angiopoietin-2 (isoform b)O15123
Cancer
Angiopoietin-related protein 4 (isoform a)Q9BY76
Cancer
Angiopoietin-related protein 4 (isoform b)Q9BY76
Cancer
Angiotensin receptor (AT) (nonspecified subtype)Q9Y2T3
P01116
O14793
DiabetesCancer
Angiotensin-converting enzyme precursor (isoform 1)P12821
Cancer
Diabetes
Malaria
Angiotensin-converting enzyme precursor (isoform 2)P12821
Cancer
Diabetes
Malaria
Angiotensin-converting enzyme precursor (isoform 3)P12821
Cancer
Diabetes
Malaria
Anoctamin-1Q5XXA6
Cancer
Anterior gradient protein 2 homologO95994
Cancer
AntileukoproteinaseP03973
Cancer
Anti-Muellerian hormone type-2 receptor (isoform 1)Q16671
Cancer
Anti-Muellerian hormone type-2 receptor isoform 2 precursorQ16671
Cancer
Anti-Muellerian hormone type-2 receptor isoform 3 precursorQ16671
Cancer
Apelin receptorP35414
DiabetesCancer
Apolipoprotein B-100P04114
DiabetesCancer
ApomucinP98088
Cancer
Apoptosis regulator BAX (Bcl-2-associated X protein; Bax)Q07814
1N45

Cancer
Diabetes
Apoptosis regulator BAX isoform 1Q07812
Cancer
Diabetes
Apoptosis regulator Bcl-2 (isoform alpha)P10415
CancerDiabetes
Apoptosis regulator Bcl-2 (isoform beta)P10415
CancerDiabetes
Aquaporin-1 (isoform 1)P29972
Cancer
Aquaporin-1 (isoform 2)P29972
Cancer
Aquaporin-3Q92482
Cancer
Arachidonate 12-lipoxygenase, 12S-typeP18054
Malaria
Diabetes
Cancer
Arachidonate 5-lipoxygenase (5-LOX)P09917
DiabetesCancer
Arachidonate 5-lipoxygenase-activating protein (isoform 1)P20292
Cancer
Arachidonate 5-lipoxygenase-activating protein (isoform 2)P20292
Cancer
Arginase (nonspecified subtype)P08581
Cancer
Arginase type IP05089
Cancer
Arginase type IIP78540
Cancer
AromataseP11511
CancerDiabetes
Aryl hydrocarbon receptor (AhR)P35869
CancerDiabetes
Arylamine N-acetyltransferase 1P18440
Cancer
Asparagine synthetase [glutamine-hydrolyzing] (isoform a)P08243
Cancer
AT2P50052
Diabetes
Cancer
ATP citrate synthase (isoform 1)P53396
DiabetesCancer
ATPase family AAA domain-containing protein 2Q6PL18
Cancer
ATP-binding cassette sub-family G member 2 (isoform 1)Q9UNQ0
Cancer
Diabetes
ATP-dependent RNA helicase DDX3XO00571
Cancer
Atypical chemokine receptor 3 (isoform 2)P25106
Cancer
Aurora Kinase (nonspecified subtype)P08581
CancerDiabetes
Aurora kinase AO14965
CancerDiabetes
Aurora kinase BQ96GD4
CancerDiabetes
Aurora kinase C (isoform 1)Q9UQB9
Cancer
Aurora kinase C (isoform ASV)Q9UQB9
Cancer
Baculoviral IAP repeat-containing protein 2Q13490
Cancer
Baculoviral IAP repeat-containing protein 3Q13489
Cancer
Baculoviral IAP repeat-containing protein 5 (isoform 1)O15392
Cancer
Baculoviral IAP repeat-containing protein 5 (isoform 2)O15392
Cancer
Baculoviral IAP repeat-containing protein 5 (isoform 3)O15392
Cancer
Basigin (isoform 4)P35613
Cancer
Basigin precursor (isoform 1)P35613
Cancer
Basigin precursor (isoform 2)P35613
Cancer
B-cell lymphoma 3 protein (isoform X1)P20749
Cancer
B-cell lymphoma 3 proteinP20749
Cancer
B-cell lymphoma 6 protein (isoform 1)P41182
Cancer
B-cell lymphoma 6 proteinP41182
Cancer
BCL2-associated X protein delta isoformQ07812

Cancer
Diabetes
Bcl-2-like protein 1 (isoform 1)Q07817
Cancer
Bcl-2-like protein 2Q92843
Cancer
BCL2-related protein A1 (isoform 1)Q16548
Cancer
BDNF/NT-3 growth factors receptor (isoform a)Q16620
CancerDiabetes
BDNF/NT-3 growth factors receptor (isoform b)Q16620
CancerDiabetes
BDNF/NT-3 growth factors receptor (isoform c)Q16620
CancerDiabetes
beta2-AdrenoceptorP07550
DiabetesCancer
Epilepsy
beta-Adrenoceptor (nonspecified subtype)
Cancer
beta-Galactosidase (isoform a)P16278
Cancer
Diabetes
Beta-galactoside alpha-2,6-sialyltransferaseP15907
Cancer
beta-GlucuronidaseP08236
CancerMalaria
Beta-nerve growth factor precursorP01138
Cancer
beta-Secretase (nonspecified subtype)
CancerEpilepsy
Beta-secretase 1 preproprotein (isoform C)P56817
Epilepsy
Cancer
Beta-site APP-cleaving enzyme 1P56817
Cancer
Diabetes
Epilepsy
Bifunctional glutamate/proline--tRNA ligaseP07814
Cancer
Bifunctional polynucleotide phosphatase/kinaseQ96T60
Cancer
Bifunctional purine biosynthesis protein PURHP31939
Cancer
Bile acid receptor (isoform 1)Q96RI1
CancerDiabetes
Bile acid receptor (isoform 2)Q96RI1
Cancer
Leishmaniasis
Diabetes
Bile salt-activated lipaseP19835
Cancer
B-lymphocyte antigen CD20P11836
CancerDiabetes
Bombesin receptor (nonspecified subtype)
Cancer
Bombesin receptor subtype-3P32247
Cancer
Diabetes
Bone marrow stromal antigen 2 precursorQ10589
Cancer
Bone morphogenetic protein 10O95393
Cancer
Bone morphogenetic protein 4P12644
Diabetes
Cancer
Bone Morphogenetic Protein Receptor (nonspecified subtype)
Cancer
Bone Morphogenetic Protein Receptor Type I (nonspecified subtype)
Cancer
BPI fold-containing family A member 1 precursorQ9NP55
Cancer
Bradykinin B1 receptorP46663
CancerDiabetes
Bradykinin B2 receptor (B2R)P30411
Cancer
Bradykinin receptor (nonspecified subtype)
Cancer
B-Raf kinaseP15056
Cancer
Branched-chain-amino-acid aminotransferase, cytosolic (isoform 1)P54687
Cancer
Breakpoint cluster region protein (BCR)P11274
Cancer
Diabetes
Malaria
Breast cancer type 1 susceptibility protein (isoform 2)P38398
Cancer
Breast cancer type 1 susceptibility protein (isoform 3)P38398
Cancer
Breast cancer type 1 susceptibility proteinP38398
Cancer
Brefeldin A-inhibited guanine nucleotide-exchange protein 1Q9Y6D6
Cancer
Brefeldin A-inhibited guanine nucleotide-exchange protein 2Q9Y6D5
Cancer
Bromodomain adjacent to zinc finger domain protein 2A (isoform 1)Q9UIF9
Cancer
Bromodomain adjacent to zinc finger domain protein 2BQ9UIF8
Cancer
Bromodomain testis-specific proteinQ58F21
Cancer
Bromodomain-containing protein 1O95696
Cancer
Bromodomain-containing protein 2 (isoform 1)P25440
CancerDiabetes
Bromodomain-containing protein 3 (Brd3)Q15059
CancerDiabetes
Bromodomain-containing protein 4 (isoform long)O60885
CancerDiabetes
Bromodomain-containing protein 4 (isoform short)O60885
CancerDiabetes
Bromodomain-containing protein 7 (isoform 1)Q9NPI1
Cancer
Bromodomain-containing protein 9Q9H8M2
Cancer
Bruton Tyrosine Kinase (BTK)Q06187
Cancer
Diabetes
BUB1 budding uninhibited by benzimidazoles 1 homolog (BUB1)O43683
Cancer
c2P53778
Cancer
C5a anaphylatoxin chemotactic receptor 1P21730
Cancer
CAAX prenyl protease 2 (isoform 1)Q9Y256
Cancer
CAD proteinP27708
Cancer
Cadherin-2 preproproteinP19022
Cancer
Cadherin-3P22223
Cancer
Cadherin-5P33151
Cancer
Calcitonin Gene-Related Peptide 1P06881
Diabetes
Calcitonin gene-related peptide type 1 receptor precursorQ16602
Diabetes
Calcitonin receptor isoform 1P30988
Diabetes
Calcitonin receptor isoform 2 precursorP30988
Diabetes
CalcitoninP01258
Cancer
Calcium channels (nonspecified subtype)
Cancer
Epilepsy
MalariaDiabetes
Leishmaniasis
Calcium release-activated channel (CRAC)
Cancer
Calcium/calmodulin-dependent protein kinase (nonspecified subtype)
Cancer
Calcium/calmodulin-dependent protein kinase kinase 1 isoform aQ8N5S9
Cancer
Calcium/calmodulin-dependent protein kinase kinase 2 (isoform 1)Q96RR4
Cancer
Calcium/calmodulin-dependent protein kinase type II (CaMK-II)
Diabetes
Cancer
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaMK-IIalpha)Q9UQM7
Diabetes
Cancer
Calcium-activated chloride channel regulators (nonspecified subtype)
Cancer
Calcium-sensing receptor (CaSR)P41180
CancerDiabetes
CalmodulinP62158
Cancer
Calpain (nonspecified subtype)
Diabetes
Cancer
Epilepsy
cAMP Phosphodiesterase (nonspecified subtype)
Cancer
Diabetes
cAMP Responsive Element Binding Protein (CREB) (nonspecified subtype)
Cancer
cAMP responsive element binding protein 5 (isoform alpha)Q02930
Cancer
Diabetes
CAMPATH-1 antigen precursorP31358
Cancer
cAMP-Dependent protein kinase (PKA)
CancerMalaria
Epilepsy
Diabetes
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (isoform 1)Q07343
Cancer
Diabetes
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (isoform 2)Q07343
Diabetes
Cancer
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (isoform 3)Q07343
Diabetes
Cancer
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (isoform 1)Q08499
Cancer
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (isoform 2)Q08499
Cancer
Cancer/testis antigen 1P78358

Cancer
Cannabinoid receptor (nonspecified subtype)
EpilepsyDiabetes
Cancer
Cannabinoid receptor 1 (isoform a)P21554
Malaria
Epilepsy
Cancer
Diabetes
Cannabinoid receptor 2P34972
Malaria
Diabetes
Epilepsy
Cancer
Caprin-1 (isoform 1)Q14444
Cancer
Carbonic anhydrase 12O43570
Cancer
Carbonic anhydrase 13Q8N1Q1
EpilepsyCancer
Carbonic anhydrase 14Q9ULX7
EpilepsyCancer
Carbonic anhydrase 3P07451
Epilepsy
Cancer
Carbonic anhydrase 5A, mitochondrial precursorP35218
Cancer
Carbonic anhydrase 5B, mitochondrialQ9Y2D0
Cancer
Carbonic anhydrase 9Q16790
CancerDiabetes
Carbonic Anhydrase V (nonspecified subtype)
Cancer
Epilepsy
Carbonyl reductase 1P16152
Cancer
Carboxylesterase 1 precursor (isoform 1)P23141
Cancer
Carboxylesterase 1 precursor (isoform b)P23141
Cancer
Carboxylesterase 1 precursor (isoform c)P23141
Cancer
Carboxylesterase 2O00748
Cancer
Diabetes
Carboxypeptidase A (nonspecified subtype)
Cancer
Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEA) (nonspecified subtype)
Cancer
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)P13688
Cancer
Carcinoembryonic antigen-related cell adhesion molecule 5 preproproteinP06731
Cancer
Carcinoembryonic antigen-related cell adhesion molecule 6P40199
Cancer
Carnitine O-Palmitoyltransferase 1 (CPT-1) (nonspecified subtype)
DiabetesCancer
Casein kinase I (nonspecified subtype)
Cancer
Diabetes
Casein kinase I isoform alpha (isoform 1)P48729
CancerMalaria
Casein kinase I isoform alpha (isoform 2)P48729
CancerMalaria
Casein kinase I isoform delta isoform 1P48730
Cancer
Casein kinase I isoform delta isoform 2P48730
Cancer
Casein kinase I isoform epsilonP49674
Cancer
Diabetes
Casein kinase II (CKII) (nonspecified subtype)
CancerDiabetes
Casein kinase II subunit alpha'P19784
Cancer
Casein kinase II subunit alphaP68400
Cancer
Casein kinase II subunit betaP67870
CancerDiabetes
CASP8 and FADD-like apoptosis regulator precursor (isoform 2)O15519
Cancer
CASP8 and FADD-like apoptosis regulatorO15519
Cancer
Caspase (nonspecified subtype)
CancerDiabetes
Caspase-1 (isoform alpha)P29466
DiabetesCancerEpilepsy
Caspase-2 (isoform 1)P42575
Cancer
Caspase-7 (isoform alpha)P55210
Cancer
Caspase-7 (isoform beta)P55210
Cancer
Caspase-8 (isoform A)Q14790
EpilepsyCancer
Caspase-9P55211
Cancer
Cat eye syndrome critical region protein 2Q9BXF3
Cancer
Catechol O-methyltransferase membrane-boundP21964
Cancer
Catechol O-methyltransferase soluble formP21964
Cancer
Catenin beta-1P35222
Cancer
Cathepsin BP07858
Malaria
Leishmaniasis
Diabetes
Cancer
Cathepsin DP07339
Malaria
Cancer
Diabetes
Cathepsin F precursorQ9UBX1
Cancer
Cathepsin KP43235
Leishmaniasis
Malaria
Diabetes
Cancer
Cathepsin LP07711
Malaria
Epilepsy
Diabetes
Cancer
Cathepsin S (isoform (1)P25774
CancerMalaria
Diabetes
Caveolin-1 (isoform alpha)Q03135
Cancer
C-C chemokine receptor type 1 (CCR1)P32246
CancerDiabetes
C-C chemokine receptor type 10P46092
Cancer
C-C chemokine receptor type 2 (CCR2) (isoform B)P41597
CancerDiabetes
C-C chemokine receptor type 4P51679
Cancer
C-C chemokine receptor type 5P51681
DiabetesCancer
C-C chemokine receptor type 6P51684
Cancer
C-C chemokine receptor type 7P32248
Cancer
C-C chemokine receptor type 8 (CCR-8)P51685
Cancer
C-C chemokine receptor type 9P51686
Cancer
C-C motif chemokine 2 precursorP13500
Cancer
CCK receptor (nonspecified subtype)
Cancer
Epilepsy
CCK1P32238
CancerEpilepsyDiabetes
CCK2P32239
CancerDiabetes
CD160 antigen precursorO95971
Cancer
CD166 antigen (isoform 2)Q13740
Cancer
CD166 antigenQ13740
Cancer
CD19 antigenP15391
Cancer
CD200 antigen (isoform a)P41217
Cancer
CD22 antigenP20273
Cancer
CD226 moleculeQ15762
Cancer
CD27P26842
Cancer
CD276 antigenQ5ZPR3
Cancer
CD3 Complex (T Cell Receptor Complex)
Cancer
Diabetes
CD59 glycoprotein preproproteinP13987
Cancer
CD59 glycoproteinP13987
Cancer
CD63 antigenP08962
Cancer
CD70 antigenP32970
Cancer
CD9 antigenP21926
Cancer
CDK1/Cyclin B
CancerLeishmaniasis
Diabetes
CDK2/Cyclin A
CancerDiabetes
CDK2/Cyclin E
Cancer
CDK3/Cyclin E
Cancer
CDK4/Cyclin D
Cancer
CDK4/Cyclin D1
Cancer
CDK4/Cyclin D3
Cancer
CDK5/p25
Cancer
CDK6/Cyclin D1
Cancer
CDK6/Cyclin D3
Cancer
CDK7/Cyclin H
Cancer
CDK9/Cyclin T1
Cancer
CECR2-containing remodeling factor complex
Cancer
Cell division control protein 42 homologP60953
Cancer
Diabetes
Cell division cycle 25C proteinP30307
Cancer
Cell Surface Glycoprotein MUC18 (CD146)P43121
Cancer
Cellular tumor antigen p53 (isoform a)P04637
CancerDiabetes
Centromere-associated protein EQ02224
Cancer
Centrosome-associated protein CEP250 (isoform X3)Q9BV73
Cancer
Centrosome-associated protein CEP250Q9BV73
Cancer
Ceramidase (isoform a)Q13510
Cancer
Ceramidase (isoform b)Q13510
Cancer
Ceramidase (nonspecified subtype)
Cancer
Ceramide glucosyltransferaseQ16739
Cancer
Diabetes
Ceramide kinaseQ8TCT0
Cancer
CFTR inhibitory factorQ9HZR3
Cancer
cGMP Phosphdiesterase (PDE) (nonspecified subtype)
Diabetes
Cancer
cGMP-dependent 3',5'-cyclic phosphodiesterase (isoform PDE2A1)O00408
Malaria
Diabetes
Cancer
cGMP-dependent 3',5'-cyclic phosphodiesterase (isoform PDE2A2)O00408
Malaria
Diabetes
Cancer
cGMP-dependent 3',5'-cyclic phosphodiesterase (isoform PDE2A3)O00408
Malaria
Diabetes
Cancer
cGMP-dependent 3',5'-cyclic phosphodiesterase (isoform PDE2A4)O00408
Malaria
Diabetes
Cancer
cGMP-inhibited 3',5'-cyclic phosphodiesterase A (isoform 1)Q14432
Cancer
cGMP-specific 3',5'-cyclic phosphodiesterase (PDE5)O76074
Cancer
Diabetes
Malaria
Chaperone (nonspecified subtype)
MalariaDiabetesCancer
Schistosomiasis
Chemokine (C-C motif) ligand 20P78556
Cancer
Chemokine (C-C motif) receptor 2 (isoform A)P41597
CancerDiabetes
Chemokine (C-X-C motif) ligand 1P09341
Cancer
Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)O43927
Cancer
Chemokine (C-X-C motif) ligand 9Q07325
Cancer
Chemokine (C-X-C motif) receptor 3 (isoform B)P49682
Cancer
Diabetes
Chemokine CXC receptor (nonspecified subtype)
Cancer
Chloride channel (nonspecified subtype)
Cancer
Cholesteryl ester transfer protein precursorP11597
Cancer
Diabetes
Choline kinase alphaP35790
CancerMalaria
Leishmaniasis
Choline/ethanolamine kinase betaQ9Y259
CancerMalaria
Leishmaniasis
CholinesteraseP06276
Cancer
Chondroitin sulfate proteoglycan 4Q6UVK1
Cancer
Chondrolectin (isoform 2)Q9H9P2
Cancer
Chondrolectin (isoform 3)Q9H9P2
Cancer
ChondrolectinQ9H9P2
Cancer
Chromobox protein homolog 7O95931
Cancer
Chromobox protein homolog 8Q9HC52
Cancer
Chymotrypsin (nonspecified subtype)
Cancer
Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex
Cancer
Claudin 1O95832
Cancer
Claudin-18 (isoform 1)P56856
Cancer
Claudin-18 (isoform 2)P56856
Cancer
Claudin-3O15551
Cancer
Claudin-4O14493
Cancer
Claudin-6P56747
Cancer
Clusterin preproprotein (isoform 1)P10909
Cancer
c-Mer proto-oncogene tyrosine kinaseQ12866
Cancer
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (isoform a)Q11203
Cancer
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (isoform k)Q11203
Cancer
Coagulation factor IXP00740
Cancer
Coagulation factor VIIa (FVIIa)P08709
Cancer
Coagulation factor VIIIaP00451
Cancer
Coagulation factor X preproproteinP00742
Cancer
Collagen type IV alpha-3-binding protein (isoform 1)Q9Y5P4
Cancer
Collagen type IV alpha-3-binding protein (isoform 2)Q9Y5P4
Cancer
Collagen type IV alpha-3-binding protein (isoform 3)Q9Y5P4
Cancer
Collagenase 3 (MMP-13)P45452
Diabetes
Cancer
Complement C3 precursorP01024
Cancer
Complement C5P01031
Cancer
Complement Complex
CancerMalaria
Complement component 1q
Cancer
Connective tissue growth factor precursorP29279
CancerDiabetes
Connector enhancer of kinase suppressor of ras 1Q969H4
Cancer
COP9 signalosome complex subunit 5Q92905
Cancer
Corticosteroid 11-beta-dehydrogenase isozyme 1P28845
CancerDiabetes
Coxsackie virus and adenovirus receptorP78310
Cancer
Creatine Kinase (nonspecified subtype)
Cancer
CREB binding proteinQ92793
CancerSchistosomiasis
CREB-binding protein isoform bQ92793
CancerSchistosomiasis
C-type lectin domain family 14 member A precursorQ86T13
Diabetes
Cancer
CX3C chemokine receptor 1 (CX3CR1) (isoform a)P49238
Cancer
CX3C chemokine receptor 1 (CX3CR1) (isoform b)P49238
Cancer
C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype)
Cancer
Diabetes
C-X-C chemokine receptor type 1P25024
DiabetesCancer
C-X-C chemokine receptor type 2P25025
Diabetes
Cancer
C-X-C chemokine receptor type 3 (isoform A)P49682
Cancer
Diabetes
C-X-C chemokine receptor type 5 (isoform 1)P32302
Cancer
C-X-C chemokine receptor type 5 (isoform 2)P32302
Cancer
Cyclic AMP-dependent transcription factor ATF-5Q9Y2D1
Cancer
cyclic AMP-responsive element-binding protein 1 (isoform B)P16220
Cancer
Diabetes
cyclic AMP-responsive element-binding protein 1 isoform AP16220
Cancer
Diabetes
Cyclic AMP-responsive element-binding protein 3O43889
Cancer
Diabetes
Cyclic AMP-responsive element-binding protein 5 (isoform beta)Q02930
Cancer
Diabetes
Cyclin A (nonspecified subtype)
Cancer
Cyclin B (nonspecified subtype)
CancerLeishmaniasis
Cyclin D (nonspecified subtype)
Cancer
Cyclin T1O60563
Cancer
Cyclin-dependent kinase (nonspecified subtype)
CancerMalaria
Leishmaniasis
Diabetes
Cyclin-dependent kinase 1 (isoform 1)P06493
CancerEpilepsy
Diabetes
Cyclin-dependent kinase 12Q9NYV4
O15851
Cancer
Leishmaniasis
Cyclin-dependent kinase 13 (isoform 1)Q14004
Cancer
Cyclin-dependent kinase 16 (isoform 1)Q00536
Cancer
Cyclin-dependent kinase 19Q5JQZ8
Cancer
Cyclin-dependent kinase 2 (CDK2) (isoform 1)P24941
CancerDiabetes
Cyclin-dependent kinase 3 (CDK3)Q00526
Cancer
Cyclin-dependent kinase 4 (CDK4)P11802
Cancer
Cyclin-dependent kinase 5 (CDK5)Q00535
CancerEpilepsy
Diabetes
Cyclin-dependent kinase 6 (isoform 1)Q00534
Cancer
Cyclin-dependent kinase 7 (CDK7)P50613
Cancer
Cyclin-dependent kinase 8 (CDK8)P49336
Cancer
Cyclin-dependent kinase 9 (CDK9)P50750
Cancer
Cyclin-dependent kinase inhibitor (nonspecified subtype)
Cancer
Cyclin-dependent kinase inhibitor 1 isoform 2P38936
Cancer
Cyclin-dependent kinase inhibitor 1P38936
Cancer
Cyclin-dependent kinase inhibitor 1B (p27)P46527
DiabetesCancer
Cyclin-dependent kinases regulatory subunit 1P61024
Cancer
Cyclin-G-associated kinaseO14976
Cancer
Cyclin-HP51946
Cancer
Cyclooxygenase (nonspecified subtype)
Leishmaniasis
Cancer
Diabetes
Cystathionine beta-synthaseP35520
Cancer
Cysteine Protease (nonspecified subtype)
Malaria
Schistosomiasis
Leishmaniasis
Cancer
Cysteinyl leukotriene receptor 1Q9Y271
Diabetes
Epilepsy
Cancer
Cysteinyl leukotriene receptor 2Q9NS75
Cancer
Cystic fibrosis transmembrane conductance regulatorP13569
CancerDiabetes
Cystine/glutamate transporterQ9UPY5
Cancer
Cytidine deaminase (CDA)P32320
Cancer
Cytochrome b-c1 complex subunit 7P14927
DiabetesCancer
Cytochrome bc1 complex
DiabetesCancer
Cytochrome P450 11B1, mitochondrial (isoform 1)P15538
Cancer
Diabetes
Cytochrome P450 11B2, mitochondrialP19099
Diabetes
Cytochrome P450 1B1Q16678
Cancer
Cytochrome P450 26 (nonspecified subtype)
Cancer
Cytochrome P450 26A1 (CYP26A1)O43174
Cancer
Cytochrome P450 2A13Q16696
Cancer
Cytochrome P450, family 2, subfamily A, polypeptide 6P11509
Cancer
Cytohesin (nonspecified subtype)
Cancer
Cytoplasmic protein NCK1P16333
Cancer
Diabetes
Cytoplasmic tyrosine-protein kinase BMXP51813
CancerDiabetes
Cytosol aminopeptidaseP28838
Cancer
Cytosolic phospholipase A2P47712
Cancer
Cytosolic purine 5'-nucleotidaseP49902
Cancer
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)P16410
CancerDiabetes
D1P21728
Epilepsy
Cancer
D-3-phosphoglycerate dehydrogenase precursorO43175
Cancer
dCTP pyrophosphatase 1Q9H773
Cancer
DCX (DDB1-CUL4-X-box) E3 protein ligase complex
Cancer
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5P17844
Cancer
Death-associated protein kinase (nonspecified subtype)
Cancer
Death-associated protein kinase 1P53355
DiabetesCancer
Death-associated protein kinase 3O43293
Cancer
Decay accelerating factor for complement (CD55)P08174
Cancer
Delta-like 3 proteinQ9NYJ7
Cancer
Delta-like 4 proteinQ9NR61
Cancer
delta-Opioid (DOP) receptorP41143
MalariaCancer
Deoxycytidine kinaseP27707
Cancer
Deoxyhypusine synthaseP49366
Cancer
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (isoform 1)P33316
Cancer
Dermcidin preproproteinP81605
Cancer
Diacylglycerol Acyltransferase (DGAT) (nonspecified subtype)
Cancer
Diabetes
Dickkopf homolog 1 (DKK-1)O94907
Cancer
Dihydrofolate reductase (DHFR) (protozoal)
MalariaCancer
Dihydrofolate reductase (DHFR)P00374
Cancer
Dihydroorotate dehydrogenase (quinone), mitochondrialQ02127
Cancer
Malaria
Dihydropyrimidine dehydrogenase (DPD)Q12882
Cancer
Dimethylargininase (nonspecified subtype)
Cancer
Dipeptidase 1P16444
Cancer
Dipeptidyl peptidase 1 (isoform b)P53634
Cancer
Malaria
Dipeptidyl peptidase 2Q9UHL4
Cancer
Diabetes
Dipeptidyl peptidase 4P27487
Diabetes
Cancer
Malaria
Dipeptidyl peptidase 8Q6V1X1
CancerDiabetes
Dipeptidyl peptidase 9Q86TI2
Cancer
Diabetes
Dipeptidyl-peptidase I (isoform a)P53634
Cancer
Malaria
Discoidin domain-containing receptor 2 precursorQ16832
Cancer
Disintegrin and metalloproteinase domain-containing protein 17 preproproteinP78536
CancerDiabetes
Disintegrin and metalloproteinase domain-containing protein 9 precursorQ13443
Cancer
DNA (cytosine-5)-methyltransferase 1 isoform aP26358
Cancer
DNA (cytosine-5)-methyltransferase 1 isoform bP26358
Cancer
DNA (cytosine-5-)-methyltransferase 3A (isoform a)Q9Y6K1
Cancer
DNA (cytosine-5)-methyltransferase 3B (isoform 1)Q9UBC3
Cancer
DNA (cytosine-5)-methyltransferase 3B (isoform 2)Q9UBC3
Cancer
DNA dC->dU-editing enzyme APOBEC-3BQ9UH17
Cancer
DNA excision repair protein ERCC-1 (isoform 1)
Cancer
DNA excision repair protein ERCC-1 (isoform 2)P07992
Cancer
DNA excision repair protein ERCC-1 (isoform 3)P07992
Cancer
DNA ligase (nonspecified subtype)
Cancer
DNA ligase 1P18858
Cancer
DNA ligase 3 isoform beta precursorP49916
Cancer
DNA ligase 3P49916
Cancer
DNA ligase 4P49917
Cancer
DNA Methyltransferase (DNMT) (nonspecified subtype)
Cancer
DNA Polymerase (viral)
Cancer
DNA polymerase alpha catalytic subunitP09884
Cancer
DNA polymerase betaP06746
DiabetesCancer
DNA Primase (bacterial)
Cancer
DNA primase
Cancer
DNA repair protein RAD51 homolog 1 isoform 2Q06609
Cancer
DNA topoisomerase (nonspecified subtype)
Cancer
DNA topoisomerase 2-alphaP11388
Cancer
DNA topoisomerase IP11387
Q9NJG8
CancerDiabetes
Malaria
Leishmaniasis
DNA Topoisomerase II (bacterial)
Cancer
DNA Topoisomerase II (nonspecified subtype)
CancerDiabetes
DNA topoisomerase IV subunit AQ2FYS4
Cancer
DNA-(apurinic or apyrimidinic site) lyaseP27695
Cancer
DNA-Dependent Protein Kinase (DNA-PK)
Cancer
DNA-Directed RNA Polymerase (nonspecified subtype)
Cancer
DnaK (bacterial)
Cancer
Malaria
Dopamine D2 receptorP14416
DiabetesCancerEpilepsy
Dopamine receptor (nonspecified subtype)
DiabetesCancer
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (isoform 4)Q9HCR9
CancerDiabetes
Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype)
CancerDiabetes
Dual specificity mitogen-activated protein kinase kinase 1 (MEK 1)Q02750
CancerDiabetes
Dual specificity mitogen-activated protein kinase kinase 2 (MEK 2)P36507
Cancer
Dual specificity mitogen-activated protein kinase kinase 4P45985
Cancer
Dual specificity protein kinase CLK1P49759
Cancer
Dual specificity protein kinase CLK2P49760
Cancer
Diabetes
Dual specificity protein kinase CLK4Q9HAZ1
Cancer
Dual specificity protein kinase TTK (isoform 1)P33981
Cancer
Dual specificity protein phosphatase 1P28562
Cancer
Dual specificity protein phosphatase 3P51452
Cancer
Diabetes
Dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform aQ9Y463
DiabetesCancer
Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform aO43781
Cancer
Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform bO43781
Cancer
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (isoform 1)Q13627
CancerDiabetes
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (isoform 1)Q92630
Cancer
Dynamin-1Q05193
Cancer
Epilepsy
E2F Transcription Factor (nonspecified subtype)
Cancer
E2F transcription factor 1Q01094
Cancer
E3 ubiquitin-protein ligase (nonspecified subtype)
Cancer
Diabetes
E3 ubiquitin-protein ligase CHFRQ96EP1
Cancer
E3 ubiquitin-protein ligase Mdm2 (isoform g)Q00987
CancerDiabetes
E3 ubiquitin-protein ligase Mdm2 isoform aQ00987
CancerDiabetes
E3 ubiquitin-protein ligase NEDD4 (isoform 1)P46934
Cancer
E3 ubiquitin-protein ligase NEDD4 (isoform 2)P46934
Cancer
E3 ubiquitin-protein ligase RING2Q99496
Cancer
E3 ubiquitin-protein ligase RNF187Q5TA31
Cancer
E3 ubiquitin-protein ligase synoviolinQ86TM6
Cancer
EBNA-1P03211
Cancer
Ecto-NOX disulfide-thiol exchanger 1Q8TC92
Cancer
Ecto-NOX disulfide-thiol exchanger 2 isoform aQ16206
Cancer
Ectonucleoside triphosphate diphosphohydrolase 1 (isoform 1)P49961
Cancer
Diabetes
Ectonucleoside triphosphate diphosphohydrolase 1 isoform 2P49961
Cancer
Diabetes
Ectonucleoside triphosphate diphosphohydrolase 2 (isoform 1)Q9Y5L3
Cancer
Diabetes
Ectonucleoside triphosphate diphosphohydrolase 3O75355
Cancer
Diabetes
Ectonucleoside triphosphate diphosphohydrolase 5O75356
Cancer
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1P22413
Cancer
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 1 preproproteinQ13822
CancerDiabetes
EIF4F translation-initiation complex
Cancer
Elastase (nonspecified subtype)
Cancer
ELAV-like 1Q15717
Cancer
Elongation Factor 1 Complex
Cancer
Elongation factor 1-alpha 1 (EF-1-alpha-1)P68104
Cancer
Endoglin (isoform 1)P17813
Cancer
Endoglin (isofrom 2)P17813
Cancer
EndoplasminP14625
Cancer
Diabetes
Endosialin precursorQ9HCU0
Cancer
Endothelial PAS domain protein 1Q99814
Cancer
Endothelin B receptor (ET-B)P24530
Cancer
Endothelin receptor (nonspecified subtype)
Cancer
Endothelin-1 receptor (ET-A)P25101
Cancer
Endothelin-converting enzyme 1P42892
Cancer
Endothelin-converting enzyme 2O60344
Cancer
Endothelin-Converting Enzymes (ECE) (nonspecified subtype)
Cancer
Ephrin Receptor (nonspecified subtype)
Cancer
Ephrin Type-A Receptor 2 (EphA2)P29317
Cancer
Ephrin type-A receptor 3 (isoform a)P29320
Cancer
Ephrin type-A receptor 3 (isoform b)P29320
Cancer
Ephrin type-A receptor 4P54764
Cancer
Ephrin type-A receptor 5 (isoform a)P54756
Cancer
Ephrin type-A receptor 5 (isoform c)P54756
Cancer
Ephrin type-B receptor 2 (EphB2)P29323
Cancer
Ephrin type-B receptor 4 (EphB4)P54760
Cancer
Ephrin type-B receptor 6O15197
Cancer
Epidermal growth factor receptor (isoform a)P00533
CancerDiabetes
Malaria
Epidermal growth factorP01133
CancerDiabetes
Epidermal growth factor-like protein 6 precursor (isoform 1)Q9NZL7
Cancer
Epidermal growth factor-like protein 7Q9UHF1
Cancer
Epidermal retinal dehydrogenase 2Q8N3Y7
Cancer
Epithelial Cell Adhesion Molecule (Ep-CAM)P16422
Cancer
Epithelial discoidin domain-containing receptor 1 precursor (isoform 1)Q08345
Cancer
Epithelial membrane protein 2P54851
Cancer
Equilibrative nucleoside transporter 1Q99808
Cancer
Equilibrative nucleoside transporter 2Q14542
Cancer
ERK (nonspecified subtype)
CancerDiabetes
Epilepsy
Erythropoietin receptor precursorP19235
CancerDiabetes
ErythropoietinP01588
Cancer
E-selectinP16581
Cancer
Estradiol 17b-dehydrogenase 1P14061
Cancer
Estradiol 17-beta-dehydrogenase 2P37059
Cancer
Estrogen receptor (nonspecified subtype)
CancerDiabetes
Estrogen receptor isoform 1P03372
CancerDiabetes
Estrogen receptor-beta (isoform 1)Q92731
CancerDiabetes
Estrogen-related receptor gamma (isoform 1)P62508
Diabetes
Cancer
Euchromatic histone methyltransferase 1Q9H9B1
Cancer
Euchromatic histone-lysine N-methyltransferase 2 (isoform a)Q96KQ7
Cancer
Malaria
Eukaryotic elongation factor 2 kinaseO00418
Cancer
Eukaryotic initiation factor 4A-IIIP38919
Cancer
Eukaryotic translation initiation factor 2-alpha kinase 1 isoform aQ9BQI3
Cancer
Eukaryotic translation initiation factor 2-alpha kinase 3Q9NZJ5
DiabetesCancer
Eukaryotic translation initiation factor 2-alpha kinase 4Q9P2K8
Cancer
Eukaryotic translation initiation factor 4 gamma 1 (isoform 1)Q04637
Cancer
Eukaryotic translation initiation factor 4 gamma 1 (isoform 5)Q04637
Cancer
Eukaryotic translation initiation factor 4 gamma 2P78344
Cancer
Eukaryotic translation initiation factor 4 gamma 3 (isoform 1)O43432
Cancer
Eukaryotic translation initiation factor 4A isoform 1P60842
Cancer
Eukaryotic translation initiation factor 4A, isoform 2Q14240
Cancer
Eukaryotic translation initiation factor 4E (isoform 1)P06730
Cancer
Exportin-1O14980
Cancer
FACT complex
Cancer
Falcipain-2AQ8I6U4
CancerMalaria
Farnesyl pyrophosphate synthaseP14324
Q57WF1
CancerMalaria
Fascin 1Q16658
Cancer
Fatty acid amide hydrolaseO00519
CancerDiabetes
Epilepsy
Fatty acid binding protein 4, adipocyteP15090
Cancer
Diabetes
Fatty acid desaturase 1O60427
Diabetes
Cancer
Fatty-acid synthaseP49327
CancerDiabetes
Leishmaniasis
Malaria
F-box only protein 3 (isoform 1)Q9UK99
Cancer
Malaria
Fc alpha receptor (isoform a)P24071
Cancer
Fc-gamma Receptor (FCGR) (nonspecified subtype)
Cancer
Ferritin
Cancer
Fibroblast growth factor (FGF) (nonspecified subtype)
Cancer
Fibroblast growth factor 8 precursor (isoform A)P55075
Cancer
Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype)
Cancer
Fibroblast growth factor receptor 1 (isoform 1)P11362
Diabetes
Cancer
Fibroblast growth factor receptor 2 (isoform 1)P21802
Cancer
Fibroblast growth factor receptor 3 (FGFR-3) (isoform 1)P22607
Cancer
Fibroblast growth factor receptor 4 (isoform 1)P22455
Cancer
Fibroblast growth factor receptor 4 (isoform 2)P22455
Cancer
FibronectinP02751
Cancer
FK506 binding protein 4Q02790
Cancer
Flap endonuclease 1P39748
Cancer
fMet-Leu-Phe receptorP21462
Cancer
Focal adhesion kinase 1 (isoform a)Q05397
Cancer
Focal adhesion kinase 1 (isoform b)Q05397
Cancer
Focal Adhesion Kinases (FAK) (nonspecified subtype)
Cancer
Folate Receptor (nonspecified subtype)
Diabetes
Cancer
Folate receptor alphaP15328
Cancer
Folate receptor beta precursorP14207
Cancer
Follicle-stimulating hormone receptor isoform 1 precursorP23945
Cancer
Diabetes
Folylpolyglutamate synthase, mitochondrialQ05932
Cancer
Forkhead box O3AO43524
Cancer
Formin homology 2 domain-containing proteins (nonspecified subtype)
Cancer
Free fatty acid receptor 1 (GPR40)O14842
DiabetesCancer
Free fatty acid receptor 2O15552
Cancer
Diabetes
Free fatty acid receptor 4Q5NUL3
DiabetesCancer
Friend leukemia integration 1 transcription factor isoform 1Q01543
Cancer
Frizzled-7 receptorO75084
Cancer
Fructose-bisphosphate aldolase CP09972
Cancer
Fucosyl GM1
Cancer
FurinP09958
Cancer
Diabetes
G protein-Coupled Inwardly-Rectifying Potassium Channel (GIRK) (nonspecified subtype)
Cancer
Epilepsy
Diabetes
G protein-coupled receptor 23Q99677
Cancer
G protein-coupled receptor 39O43194
Cancer
Diabetes
G protein-coupled receptor 49O75473
Cancer
G protein-coupled receptor kinase 5 (GRK5)P34947
Cancer
Diabetes
G protein-coupled receptor kinase 6 (GRK6) (isoform b)P43250
Cancer
Diabetes
G protein-coupled receptor kinase 6 (GRK6) (isoform c)P43250
Cancer
Diabetes
G1/S-specific cyclin-D1P30305
P15428
P24385
CancerMalaria
G1/S-specific cyclin-D3 isoform 2P30281
P15428
Cancer
G1/S-specific cyclin-E1P24864
Cancer
G1/S-specific cyclin-E2O96020
Cancer
GABA(A) receptorP36639
P11021
O15530
O00763
EpilepsyCancer
Diabetes
GABA(B) Receptor (nonspecified subtype)
Epilepsy
Cancer
GalactokinaseP51570
Cancer
Galactoside 3(4)-L-fucosyltransferaseP21217
CancerDiabetes
Galanin receptor type 1P47211
CancerEpilepsy
Galectin-3 isoform 1P22303
Cancer
Galectin-3 isoform 2Q07912
P55263
P22303
Cancer
Gamma-aminobutyric acid type B receptor subunit 1 precursor (isoform a)Q9UBS5
EpilepsyCancer
Gamma-aminobutyric acid type B receptor subunit 1 precursor (isoform b)Q9UBS5
EpilepsyCancer
Gamma-aminobutyric acid type B receptor subunit 1 precursor (isoform c)Q9UBS5
EpilepsyCancer
Gamma-aminobutyric acid type B receptor subunit 2 precursorO75899
EpilepsyCancer
gamma-SecretaseP23526
CancerDiabetes
Gap junction alpha-8 proteinP48165
Cancer
Gap junction Connexin ( (nonspecified subtype)Q15109
Q10588
P62330
DiabetesCancer
Epilepsy
Gap junction delta-2 proteinQ15109
Cancer
Gap Junction Protein (nonspecified subtype)Q15109
P11766
P05091
DiabetesCancer
Epilepsy
Gastric Inhibitory Polypeptide Receptor (GIP-R)P05091
P48546
DiabetesCancer
Gastrin-releasing peptide receptorP05091
Cancer
Gelatinase BP49419
P14780
CancerDiabetes
Ghrelin receptor (isoform 1a)Q92847
CancerDiabetes
Ghrelin receptor (isoform 1b)Q92847
CancerDiabetes
Glucagon-like peptide 1 receptor precursorP21397
P08913
P43220
DiabetesCancer
Glucagon-like peptide 2 receptor precursorP21397
O95838
CancerDiabetes
Glucocorticoid receptor (isoform alpha)P27338
P04150
CancerDiabetes
Glucocorticoid receptor (isoform beta)P27338
P04150
Diabetes
Cancer
Glucose-6-phosphataseP35575
Cancer
Diabetes
Glucose-dependent insulinotropic receptorQ8TDV5
DiabetesCancerEpilepsy
Glucosylceramidase isoform 1 precursorP04062
Cancer
Diabetes
Glutamate carboxypeptidase II (isoform 1)P05067
Q04609
CancerEpilepsy
Glutamate Receptor Ionotropic AMPA ReceptorP05067
Epilepsy
Diabetes
Glutamate receptor ionotropic, NMDA 2A (isoform 1)P05067
Q12879
Epilepsy
Glutamate receptor ionotropic, NMDA 2A (isoform 2)P05067
Q12879
Epilepsy
Glutamate receptor ionotropic, NMDA 2BP05067
Q13224
CancerEpilepsy
Glutamate Transporter (nonspecified subtype)P05067
EpilepsyCancer
Glutaminase (nonspecified subtype)P05067
CancerMalaria
Glutaminase kidney isoform, mitochondrial (isoform 1)P05067
Cancer
Glutathione peroxidase (nonspecified subtype)P05067
CancerDiabetes
Glutathione reductase, mitochondrial precursor (isoform 1)P05067
P00390
Malaria
Schistosomiasis
Diabetes
Cancer
Glutathione S-Transferase (GST) (nonspecified subtype)P10275
CancerDiabetes
Glutathione S-transferase omega-1 (isoform 2)P10275
Cancer
Glutathione S-transferase omega-1 (isoform 3)
Cancer
Glutathione S-transferase piP10275
Cancer
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)P10275
P04406
LeishmaniasisCancer
Glycine receptorP10275
Cancer
Epilepsy
Diabetes
Glycogen phosphorylase (nonspecified subtype)P10275
CancerDiabetes
Glycogen phosphorylase, liver form (isoform 1)P10275
P06737
Diabetes
Cancer
Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype)P10275
EpilepsyMalaria
Diabetes
Cancer
Glycogen synthase kinase-3 alphaP49840
Diabetes
Cancer
Glycoprotein A33Q02763
Cancer
Glycylpeptide N-tetradecanoyltransferase 1Q02763
Cancer
Glypican-3Q02763
Cancer
Golgi apparatus protein 1
Cancer
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (isoform 1)
Cancer
Gonadotropin-releasing hormone receptor (isoform 1)Q02763
Cancer
GPBAQ02763
Q8TDU6
DiabetesCancer
G-protein coupled estrogen receptor 1Q99527
CancerDiabetes
G-protein coupled receptor 182O15218
Cancer
G-protein coupled receptor 183Q5JUH7
Cancer
Diabetes
G-protein coupled receptor 35 isoform aQ9HC97
P07992
Cancer
G-protein coupled receptor 55
Cancer
Granulin (GP88) (isoform 1)Q02763
Cancer
Granulocyte colony-stimulating factor precursor (isoform a)Q02763
Cancer
Granulocyte colony-stimulating factor receptor precursor (isoform a)Q02763
Cancer
Granzyme H precursor
Cancer
Group IID secretory phospholipase A2 (sPLA2)Q02763
O15123
Cancer
Growth differentiation factor 11O15123
Cancer
Growth differentiation factor 15
Cancer
Growth factor receptor-bound protein 2 (isoform 1)O15123
P62993
Diabetes
Cancer
Growth factor receptor-bound protein 7 isoform bO15123
Cancer
Growth factor receptor-bound protein 7O15123
Cancer
Growth hormone receptor precursor (isoform 1)O15123
P10912
Cancer
Diabetes
Growth hormone-releasing hormone receptor precursorO15123
Cancer
Growth/differentiation factor 2O15123
Cancer
Growth/differentiation factor 8O14793
DiabetesCancer
GTPase KRas precursor (isoform a)
Cancer
Guanine deaminase isoform b
Cancer
Guanylate cyclase (nonspecified subtype)P12821
DiabetesCancer
Guanylate cyclase 2CP12821
Cancer
H1P12821
P35367
CancerMalaria
H2P12821
Cancer
H3P12821
Q9Y5N1
Malaria
Cancer
Diabetes
Epilepsy
H4P12821
Cancer
HaspinP12821
Cancer
Heat Shock Protein 27 (Hsp27) (nonspecified subtype)P12821
Cancer
Heat shock protein 70 (nonspecified subtype)P12821
CancerMalariaDiabetes
Heat shock protein 90 (nonspecified subtype)P12821
CancerMalariaDiabetes
Heat shock protein HSP 90-alpha (isoform 2)P12821
Cancer
Heat shock protein HSP 90-beta (isoform a)P12821
Cancer
Heat shock protein HSP 90-beta (isoform c)P12821
Cancer
Heat shock transcription factor 1P12821
Cancer
Hedgehog Protein (nonspecified subtype)P12821
CancerDiabetes
Heme oxygenase (decyclizing) 2P30519
Cancer
Heme oxygenase 1 (HO-1)P10415
P09601
Diabetes
Cancer
Heparanase (isoform 1)P10415
Q9Y251
CancerDiabetes
Heparin-binding growth factor 1 proprotein (isoform 1)P10415
Cancer
Heparin-binding growth factor 2P10415
P09038
CancerEpilepsy
Hepatitis A virus cellular receptor 1
Cancer
Hepatitis A virus cellular receptor 2 (TIM-3)P10415
Cancer
Hepatocyte growth factor (HGF)P10415
Cancer
Hepatocyte growth factor (isoform 3)P10415
Cancer
Hepatocyte growth factor activator (HGFA)
Cancer
Hepatocyte growth factor receptor precursor (isoform a)P20292
P15056
P11836
P10415
O14965
P08581
CancerDiabetes
R-spondin 3 homologQ9BXY4
Cancer
Ribosomal protein S6 kinase alpha-1Q15418
Diabetes
Cancer
Ribose-phosphate pyrophosphokinase 2 (isoform 2)P11908
Cancer
Ribose-phosphate diphosphokinase 1P60891
Cancer
Ribonucleoside-diphosphate reductase
Cancer
Ribonucleoside-diphosphate reductase large subunitP23921
Cancer
Ribonuclease P protein subunit p30 isoform aP78346
Cancer
Ribonuclease P protein subunit p14O95059
Cancer
Ribonuclease P Complex
Cancer
Rho-related GTP-binding protein RhoC precursorP08134
Cancer
Rho-associated protein kinase 2 (ROCK2)O75116
CancerDiabetes
Malaria
Rho-associated protein kinase 1 (ROCK1)Q13464
CancerDiabetes
Rho kinase (ROCK) (nonspecified subtype)
Diabetes
Cancer
Rho guanine nucleotide exchange factor 12 isoform 2Q9NZN5
Cancer
Rho guanine nucleotide exchange factor (GEF) 12Q9NZN5
Cancer
Rho GTPase (nonspecified subtype)
Cancer
Diabetes
Retinoid RXRgamma receptorP48443
CancerDiabetes
Retinoid RXRbeta receptorP28702
Cancer
Diabetes
Retinoid RXR receptor (nonspecified subtype)
Cancer
Diabetes
Retinoid acid receptor (nonspecified subtype)
Cancer
Retinoic acid receptor RXR-alpha isoform aP19793
CancerDiabetes
Retinoic acid receptor gamma isoform 1P13631
Cancer
Retinoic acid receptor beta (isoform 2)P10826
Cancer
Retinoic acid receptor beta (isoform 1)P10826
Cancer
Retinoic acid receptor alpha (isoform 1)P10276
Cancer
Retinal dehydrogenase 1P00352
Cancer
Replication Protein A Complex (RPA)
Cancer
ReninP00797
Diabetes
Cancer
Renalase precursor (isoform 2)Q5VYX0
Cancer
Renalase (isoform 1)Q5VYX0
Cancer
Receptor-type tyrosine-protein phosphatase C isoform 1 precursorP08575
Cancer
Diabetes
Receptor-type tyrosine-protein kinase FLT3P36888
CancerDiabetes
Receptor-interacting serine-threonine kinase 2O43353
Cancer
Diabetes
Receptor-interacting serine/threonine-protein kinase 1Q13546
Cancer
Receptor tyrosine-protein kinase erbB-4 (isoform JM-a/CVT-2)Q15303
Cancer
Receptor tyrosine-protein kinase erbB-4 (isoform JM-a/CVT-1)Q15303
Cancer
Receptor tyrosine-protein kinase erbB-3 precursor (isoform 1)P21860
Cancer
Receptor tyrosine-protein kinase erbB-2 (isoform d)P04626
Cancer
Receptor tyrosine-protein kinase erbB-2 (isoform b)P04626
Cancer
Receptor tyrosine-protein kinase erbB-2 (isoform a)P04626
Cancer
Ras-related C3 botulinum toxin substrate 1 (isoform Rac1b)P63000
Cancer
Ras-related C3 botulinum toxin substrate 1 (isoform Rac1)P63000
Cancer
Ras GTPse (nonspecified subtype)
CancerDiabetes
RAP guanine-nucleotide-exchange factor 3O95398
Cancer
Rap guanine nucleotide exchange factor 4 (isoform a)Q8WZA2
Cancer
RAF proto-oncogene serine/threonine-protein kinaseP04049
Cancer
Raf kinase (nonspecified subtype)
Cancer
RAD51 homolog proteinQ06609
Cancer
RAC-gamma serine/threonine-protein kinase isoform 1Q9Y243
Cancer
RAC-beta serine/threonine-protein kinase isoform 1P31751
CancerDiabetes
RAC-alpha serine/threonine-protein kinaseP31749
CancerDiabetes
Quinolone resistance proteinP0A0J7
CancerMalaria
Leishmaniasis
Pyruvate kinase, liver and RBC (isoform 1)P30613
Cancer
Pyruvate kinase isozymes M1/M2 (isoform c)P14618
Cancer
Pyruvate kinase isozymes M1/M2 (isoform a)P14618
Cancer
Pyruvate dehydrogenase kinase, isozyme 2Q15119
Cancer
Diabetes
Pyruvate dehydrogenase kinase, isoenzyme 4Q16654
Diabetes
Cancer
Pyruvate Dehydrogenase Complex
DiabetesCancer
Putative secreted protein-tyrosine phosphataseO68720
Cancer
Putative hydrolase RBBP9O75884
Cancer
Puromycin-sensitive aminopeptidaseP55786
Cancer
Purinergic receptor P2Y11Q96G91
Diabetes
Cancer
Purine-nucleoside phosphorylaseP00491
Schistosomiasis
Cancer
Malaria
P-selectin precursorP16109
Cancer
Proto-oncogene tyrosine-protein kinase ROSP08922
Cancer
Proto-oncogene tyrosine-protein kinase receptor Ret precursor (isoform a)P07949
Cancer
Proto-oncogene tyrosine-protein kinase (SRC)P12931
CancerDiabetes
Proto-oncogene c-FosP01100
Cancer
Proton-coupled folate transporterQ96NT5
Cancer
Prothrombin preproproteinP00734
Diabetes
Cancer
Leishmaniasis
Protein-tyrosine phosphatase, non-receptor type 22 (isoform 2)Q9Y2R2
Diabetes
Cancer
Protein-tyrosine phosphatase, non-receptor type 22 (isoform 1)Q9Y2R2
Diabetes
Cancer
Protein-tyrosine kinase fyn (isoform c)P06241
CancerDiabetes
Protein-tyrosine kinase fyn (isoform b)P06241
CancerDiabetes
Protein-tyrosine kinase fyn (isoform a)P06241
CancerDiabetes
Protein-tyrosine kinase 6 isoform 1Q13882
Cancer
Protein-tyrosine kinase 2-beta (isoform a)Q14289
Cancer
Protein-serine O-palmitoleoyltransferase porcupineQ9H237
Cancer
Protein-glutamine gamma-glutamyltransferase 2 ( (TGase-2)P21980
Malaria
Cancer
Protein-cysteine N-palmitoyltransferase HHATQ5VTY9
Cancer
Proteinase-activated receptor 4 precursorQ96RI0
Cancer
Proteinase-activated receptor 2 (PAR-2) precursorP55085
Cancer
Protein-arginine deiminase type-4Q9UM07
Cancer
Protein-arginine deiminase type-1Q9ULC6
Cancer
Protein tyrosine phosphatase, receptor type, FP10586
Diabetes
Cancer
Protein tyrosine phosphatase, non-receptor type 6 (isoform 3)P29350
Diabetes
Cancer
Protein tyrosine phosphatase, non-receptor type 6 (isoform 2)P29350
Diabetes
Cancer
Protein tyrosine phosphatase, non-receptor type 6 (isoform 1)P29350
Diabetes
Cancer
Protein tyrosine phosphatase type IVA, member 3 (isoform 1)O75365
Cancer
Protein Tyrosine Phosphatase Type IVA (PTP4A; PRL Phosphatase) (nonspecified subtype)
Cancer
Protein tyrosine phosphatase non-receptor type 11 (isoform 1)Q06124
DiabetesCancer
Protein Tyrosine Phosphatase (PTP) (nonspecified subtype)
Leishmaniasis
Cancer
Diabetes
Protein S100-BP04271
Cancer
Protein S100-A4P26447
Cancer
Protein polybromo-1Q86U86
Cancer
Protein phosphatase-1
Cancer
Malaria
Protein phosphatase Slingshot homolog 2Q76I76
Cancer
Protein phosphatase Slingshot homolog 1 (isoform 1)Q8WYL5
Cancer
Protein Phosphatase 2B
DiabetesCancer
Protein Phosphatase 2A
Cancer
Protein phosphatase 1DO15297
Cancer
Protein Phosphatase (nonspecified subtype)
Cancer
Protein patched homolog 1 isoform LQ13635
CancerDiabetes
Protein O-GlcNAcase isoform aO60502
CancerDiabetes
Protein Mdm4O15151
CancerDiabetes
Protein LYRICQ86UE4
Cancer
Protein Kinase D (PKD) (nonspecified subtype)
Cancer
Protein kinase C zeta type isoform 1Q05513
Cancer
Protein kinase C theta type isoform 2Q04759
Diabetes
Cancer
Protein kinase C iotaP41743
CancerDiabetes
Protein kinase C gamma typeP05129
Cancer
Diabetes
Protein kinase C eta typeP24723
Cancer
Protein kinase C epsilonQ02156
DiabetesCancer
Protein kinase C deltaQ05655
Diabetes
Cancer
Protein kinase C beta type (isoform 2)P05771
CancerDiabetes
Protein kinase C alpha typeP17252
Cancer
Diabetes
Protein kinase C (nonspecified subtype)
CancerEpilepsy
Diabetes
Leishmaniasis
Protein Kinase B (PKB/Akt) (nonspecified subtype)
CancerDiabetesEpilepsy
Protein geranylgeranyltransferase type I
Cancer
Protein farnesyltransferase
CancerLeishmaniasisMalaria
Protein delta homolog 1P80370
Cancer
Protein cereblon (isoform 1)Q96SW2
Cancer
Protein arginine N-methyltransferase 8 (isoform 1)Q9NR22
Cancer
Protein arginine N-methyltransferase 6Q96LA8
Cancer
Protein arginine N-methyltransferase 3 (isoform 1)O60678
Cancer
Protein arginine N-methyltransferase 1 (isoform 1)Q99873
Cancer
Proteasome subunit beta type-8P28062
Cancer
Proteasome subunit beta type-5P28074
Cancer
Proteasome subunit beta type-1 precursorP20618
Cancer
Prostatic acid phosphatasen (PAP)P15309
Cancer
Prostate-specific antigen isoform 1 preproproteinP07288
Cancer
Prostate stem cell antigenO43653
Cancer
ProstasinQ16651
Cancer
Prostanoid TP receptor (Thromboxane A2 receptor; TXA2-R) (nonspecified subtype)
Diabetes
Cancer
Prostanoid EP4 receptorP35408
Cancer
Prostanoid EP2 receptorP43116
CancerEpilepsy
Prostanoid EP1 receptorP34995
Cancer
Prostaglandin-E synthaseO14684
Diabetes
Cancer
Prostaglandin G/H synthase 1 precursor (isoform 2)P23219
Cancer
Epilepsy
Schistosomiasis
Diabetes
Prostaglandin G/H synthase 1 precursor (isoform 1)P23219
Epilepsy
Cancer
Schistosomiasis
Diabetes
Prostaglandin EP Receptor (nonspecified subtype)
Cancer
Prostaglandin E2 receptor EP3 subtype isoform 4P43115
Diabetes
Cancer
Prostaglandin E receptor 3 (subtype EP3) isorform 1P43115
Cancer
Diabetes
Prostaglandin E receptor 3 (subtype EP3) isoform 5P43115
Cancer
Diabetes
Prostaglandin D2 receptorQ13258
Cancer
Prostaglandin D2 receptor 2Q9Y5Y4
Cancer
Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproproteinP29122
Cancer
Diabetes
Pro-platelet basic proteinP02775
Cancer
Prominin 1O43490
Cancer
Prolyl oligopeptidaseP48147
Cancer
Prolyl endopeptidase FAPQ12884
CancerDiabetes
Prolyl 4-hydroxylase
Cancer
Diabetes
Prolyl 4-hydroxylase subunit betaP07237
Cancer
Diabetes
Prolyl 4-hydroxylase subunit alpha-3Q7Z4N8
Cancer
Prolyl 4-hydroxylase subunit alpha-2O15460
Cancer
Diabetes
Prolyl 4-hydroxylase subunit alpha-1P13674
Cancer
Prolow-density lipoprotein receptor-related protein 1 precursorQ07954
Cancer
Proline-, glutamic acid-, leucine-rich protein 1Q8IZL8
Cancer
Proliferating cell nuclear antigenP12004
Cancer
Prolactin receptorP16471
Cancer
Prolactin precursorP01236
Cancer
Diabetes
Prokineticin receptor 2Q8NFJ6
DiabetesCancer
Prokineticin receptor 1Q8TCW9
Cancer
Diabetes
Proheparin-binding EGF-like growth factor precursorQ99075
Cancer
Programmed cell death 1 ligand 1 (PD-L1)Q9NZQ7
Cancer
Programmed cell death 1 (PD-1)Q15116
Cancer
Progonadoliberin-1 preproproteinP01148
Cancer
Progesterone receptor (isoform B)P06401
Cancer
Progesterone receptor (isoform A)P06401
CancerDiabetes
Pro-epidermal growth factor preproprotein (isoform 3)P01133
CancerDiabetes
Pro-epidermal growth factor preproprotein (isoform 2)P01133
CancerDiabetes
Probable ubiquitin carboxyl-terminal hydrolase FAF-XQ93008
Cancer
Probable global transcription activator SNF2L2 (isoform b)P51531
Cancer
Probable global transcription activator SNF2L2 (isoform a)P51531
Cancer
Preprotein translocase subunit, ATPaseP10408
Cancer
Prenyltransferase (nonspecified subtype)
Cancer
Potassium voltage-gated channel, Shaw-related subfamily, member 2 (isoform b)Q96PR1
CancerEpilepsy
Potassium voltage-gated channel subfamily S member 3Q9BQ31
CancerEpilepsy
Potassium voltage-gated channel subfamily KQT member 5Q9NR82
CancerEpilepsy
Potassium voltage-gated channel subfamily KQT member 2 (isoform 1)O43526
Cancer
Epilepsy
Potassium voltage-gated channel subfamily KQT member 1 (isoform 2)P51787
CancerEpilepsy
Potassium voltage-gated channel subfamily KQT member 1 (isoform 1)P51787
CancerEpilepsy
Potassium voltage-gated channel subfamily H member 2 (isoform c)Q12809
CancerMalaria
Potassium voltage-gated channel subfamily H member 2 (isoform b)Q12809
CancerMalaria
Potassium voltage-gated channel subfamily H member 2 (isoform a)Q12809
CancerMalaria
Potassium voltage-gated channel subfamily H member 1 (isoform 2)O95259
CancerEpilepsy
Potassium voltage-gated channel subfamily H member 1 (isoform 1)O95259
CancerEpilepsy
Potassium voltage-gated channel subfamily E member 4Q8WWG9
CancerEpilepsy
Potassium voltage-gated channel subfamily E member 3Q9Y6H6
CancerEpilepsy
Potassium voltage-gated channel subfamily E member 2Q9Y6J6
CancerEpilepsy
Potassium voltage-gated channel subfamily E member 1P15382
CancerEpilepsy
Potassium voltage-gated channel subfamily C member 3Q14003
CancerEpilepsy
Potassium voltage-gated channel subfamily C member 2 (isoform a)Q96PR1
CancerEpilepsy
Potassium voltage-gated channel subfamily C member 1 isoform 2P48547
CancerEpilepsy
Potassium voltage-gated channel subfamily A member 5 (Kv1.5)P22460
CancerEpilepsy
Diabetes
Potassium voltage-gated channel subfamily A member 3P22001
Cancer
Diabetes
Epilepsy
Potassium voltage-gated channel subfamily A member 2P16389
CancerEpilepsy
Potassium inwardly-rectifying channel J5P48544
Cancer
Diabetes
Epilepsy
Potassium inwardly-rectifying channel J3P48549
Cancer
Diabetes
Epilepsy
Potassium Channels (nonspecified subtype)
EpilepsyMalaria
Diabetes
Cancer
Potassium channel, subfamily K, member 3O14649
Cancer
Potassium channel subfamily K member 9 (isoform 2)Q9NPC2
Cancer
Potassium channel subfamily K member 18Q7Z418
Cancer
Polycomb Repressive Complex 2 (PRC2)/EED-EZH2 Complex
Cancer
Polycomb protein EED (isoform a)O75530
Cancer
Polycomb complex protein BMI-1P35226
Cancer
Polyamine oxidase (PAO-1) (isoform 1)Q96QT3
Cancer
Poly(ADP-ribose) glycohydrolaseQ9Y4W7
Cancer
Poly [ADP-ribose] polymerase 6Q2NL67
Cancer
Poly [ADP-ribose] polymerase 3 (isoform a)Q9Y6F1
Cancer
Poly [ADP-ribose] polymerase 2 (isoform 2)Q9UGN5
CancerDiabetes
Poly [ADP-ribose] polymerase 2 (isoform 1)Q9UGN5
CancerDiabetes
Poly (ADP-ribose) polymerase family, member 1 (PARP-1)P09874
CancerDiabetes
PodocalyxinO00592
Cancer
Podocalyxin (isoform 2)O00592
Cancer
Platelet-derived growth factor receptor beta precursorP09619
Cancer
Diabetes
Platelet-derived growth factor receptor alphaP16234
Malaria
Cancer
Diabetes
Platelet-derived growth factor D isoform 1 precursorQ9GZP0
Cancer
Platelet-Derived Growth Factor (PDGF) (nonspecified subtype)
CancerDiabetes
Platelet-activating factor receptorP25105
Cancer
Platelet-activating factor acetylhydrolase isoform 1B complex
Cancer
Platelet receptor Gi24 (VISTA)Q9H7M9
Cancer
Platelet glycoprotein VI isoform 2 precursorQ9HCN6
Cancer
Platelet Endothelial Cell adhesion Molecule (PECAM-1)P16284
Cancer
PlasminogenP00747
Cancer
Plasminogen activator inhibitor 1P05121
DiabetesCancer
Plasma protease C1 inhibitor precursorP05155
Cancer
Plasma kallikreinP03952
Cancer
Placental growth factor precursor (isoform 1)P49763
Cancer
Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (isoform 1)P41586
DiabetesCancer
PirinO00625
Cancer
Pim-3Q86V86
Cancer
Pim-2Q9P1W9
Cancer
Pim-1P11309
CancerDiabetes
Pim-1 isoform 44kDaP11309
CancerDiabetes
Pim Kinase (nonspecified subtype)
Cancer
Phylloquinone omega-hydroxylase CYP4F2P78329
Cancer
Photoreceptor-specific nuclear receptor (isoform a)Q9Y5X4
Cancer
Phospholipase D2O14939
Cancer
Phospholipase D1 (isoform a)Q13393
Cancer
Phospholipase C (nonspecified subtype)
Cancer
Phospholipase A2, Secretory (sPLA2) (nonspecified subtype)
CancerDiabetes
Phospholipase A2, membrane associatedP14555
CancerDiabetes
Phospholipase A2, Cytosolic (nonspecified subtype)
Cancer
Phosphoinositide-3-kinase, catalytic, gamma polypeptideP48736
CancerDiabetes
Epilepsy
Malaria
Phosphoinositide-3-kinase, catalytic, beta polypeptideP42338
CancerDiabetes
Phosphoglycerate mutase 1 (brain)P18669
Cancer
Phosphodiesterase VIII (nonspecified subtype)
Diabetes
Cancer
Phosphodiesterase VII (PDEVII; PDE7) (nonspecified protein)
Cancer
Diabetes
Phosphodiesterase IV (PDE4) (nonspecified subtype)
Diabetes
Cancer
Phosphodiesterase III (PDE3) (nonspecified subtype)
Cancer
Diabetes
Phosphodiesterase (nonspecified subtype)
LeishmaniasisMalaria
Cancer
Diabetes
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoformO00329
CancerEpilepsy
Diabetes
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoformP42336
CancerDiabetes
Epilepsy
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphataseP60484
Diabetes
Cancer
Phosphatidylinositol 4-kinase type 2-betaQ8TCG2
Cancer
Malaria
Phosphatidylinositol 4-kinase betaQ9UBF8
Cancer
Malaria
Phosphatidylinositol 4-Kinase (PI4K) (nonspecified subtype)
Cancer
Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3Q8NEB9
Cancer
Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype)
CancerLeishmaniasis
Malaria
Diabetes
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform aO00145
Cancer
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform 1Q8WUK0
DiabetesCancer
PHD finger protein 8Q9UPP1
Cancer
PGAM5-KEAP1-NRF2 Complex
Diabetes
Cancer
Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype)
CancerDiabetes
Peroxisome proliferator-activated receptor alphaQ07869
DiabetesCancer
PeriostinQ15063
Cancer
PeregrinP55201
Cancer
Peptidylprolyl isomerase D (Cyclophilin D)Q08752
DiabetesCancer
Peptidylprolyl isomerase A (isoform 1) (Cyclophilin A)P62937
Cancer
Diabetes
Peptidylprolyl Isomerase (Cyclophilin) (nonspecified subtype)
Cancer
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Q13526
Cancer
Peptidyl-prolyl cis-trans isomerase FKBP5 (isoform 1)Q13451
Cancer
Peptidyl-prolyl cis-trans isomerase FKBP1A (Rotamase)P62942
CancerDiabetes
Peptidyl arginine deiminase (PAD) (nonspecified subtype)
Cancer
Peptidase inhibitor 3, skin-derived (Elafin)P19957
Cancer
PDGFR (nonspecified subtype)
CancerDiabetes
PAS domain-containing serine/threonine kinaseQ96RG2
Cancer
Diabetes
Parathyroid hormone-like hormone (isoform 1)P12272
Cancer
Parathyroid hormone/parathyroid hormone-related peptide receptorQ03431
Cancer
Parathyroid Hormone Receptors (PTHR) (nonspecified subtype)
Cancer
Parathyroid hormone preproproteinP01270
Cancer
Pancreatic triacylglycerol lipaseP16233
CancerDiabetes
Leishmaniasis
Pancreatic elastaseQ9UNI1
Cancer
Palmitoleoyl-protein carboxylesterase NOTUMQ6P988
Cancer
P2Y purinoceptor 2P41231
Cancer
P2Y purinoceptor 13Q9BPV8
Diabetes
Cancer
P2X Receptor (nonspecified subtype)
Cancer
Oxysterols receptor LXR-alpha isoform 1Q13133
DiabetesCancer
OT-RP30559
Diabetes
Cancer
Osteopontin precursor (isoform OPN-c)P10451
Cancer
Osteopontin precursor (isoform OPN-b)P10451
Cancer
Osteopontin precursor (isoform OPN-a)P10451
Cancer
Osteopontin precursor (isoform 5)P10451
Cancer
Ornithine decarboxylase (ODC)P11926
Cancer
Ornithine aminotransferase, mitochondriaP04181
Cancer
Organic anion transporters (OATs) (nonspecified subtype)
Cancer
Opioid receptor (nonspecified subtype)
Diabetes
Cancer
Oncostatin-M Receptor
Cancer
Oncostatin MP13725
Cancer
Oligosaccharyltransferase complex
Cancer
Oligodendrocyte transcription factor 2Q13516
Cancer
Nucleosome-remodeling factor subunit BPTFQ12830
Cancer
NucleophosminP06748
Cancer
NucleolinP19338
Cancer
Nuclear receptor subfamily 5 group A member 2 (isoform 2)O00482
Cancer
Nuclear receptor subfamily 4, group A, member 1 (isoform a)P22736
DiabetesCancer
Nuclear receptor subfamily 4 group A member 2P43354
EpilepsyCancer
Nuclear receptor subfamily 1, group H, member 2P55055
Cancer
Diabetes
Nuclear receptor subfamily 1, group D, member 2Q14995
Cancer
Nuclear receptor subfamily 1, group D, member 1P20393
Cancer
Diabetes
Nuclear receptor subfamily 1 group I member 3 isoform 1Q14994
CancerDiabetes
Nuclear receptor subfamily 1 group I member 3 (isoform 6)Q14994
CancerDiabetes
Nuclear receptor subfamily 1 group I member 3 (isoform 3)Q14994
CancerDiabetes
Nuclear receptor ROR-gamma (isoform b)P51449
Leishmaniasis
Cancer
Diabetes
Nuclear receptor ROR-gamma (isoform a)P51449
Leishmaniasis
Cancer
Diabetes
Nuclear receptor ROR-betaQ92753
Cancer
Nuclear receptor coactivator 3 (isoform a)Q9Y6Q9
Cancer
Nuclear receptor coactivator 1 (isoform 1)Q15788
Cancer
NUAK family SNF1-like kinase 1O60285
Cancer
NUAK Family SNF1-like Kinase (nonspcified subtype)
Cancer
NuA4 histone acetyltransferase (HAT) complex
Cancer
NT-3 growth factor receptor (isoform c)Q16288
Cancer
NT-3 growth factor receptor (isoform b)Q16288
Cancer
NT-3 growth factor receptor (isoform a)Q16288
Cancer
Notch receptor (nonspecified subtype)
Cancer
Non-structural 4A protein
Cancer
NMDA receptor
Cancer
Epilepsy
Diabetes
N-lysine methyltransferase SMYD2Q9NRG4
Cancer
N-lysine methyltransferase KMT5AQ9NQR1
Cancer
NKG2-D type II integral membrane proteinP26718
Cancer
Diabetes
NKG2-A/NKG2-B type II integral membrane protein (isoform NKG2-A)P26715
Cancer
Nitric oxide synthase, inducibleP35228
EpilepsyCancer
Diabetes
Leishmaniasis
Nitric oxide synthase, endothelial (isoform 1)P29474
Cancer
Nitric oxide synthase, brainP29475
Cancer
Nitric oxide synthase (NOS) (nonspecified subtype)
DiabetesEpilepsy
Cancer
Nicotinic beta2 receptorP17787
Cancer
Epilepsy
Nicotinic alpha9alpha10 Receptor
Cancer
Nicotinic alpha9 receptorQ9UGM1
Cancer
Nicotinamide phosphoribosyltransferaseP43490
Cancer
Diabetes
NF-kappaB (NFkB)
Cancer
Diabetes
LeishmaniasisEpilepsy
Malaria
Neutrophil collagenase (MMP-8)P22894
DiabetesCancer
Neutral cholesterol ester hydrolase 1Q6PIU2
Cancer
Neutral amino acid transporter B(0)Q15758
Cancer
Neutral amino acid transporter B(0) (isoform 2)Q15758
Cancer
Neutral amino acid transporter AP43007
Cancer
Neurotrophic Tyrosine Kinase Receptor (TRK) (nonspecified subtype)
Cancer
Neurotrophic Factor (nonspecified subtype)
Diabetes
Epilepsy
Cancer
Neurotensin/neuromedin N preproproteinP30990
Cancer
Neurotensin receptor type 2O95665
Cancer
Neurotensin receptor type 1P30989
Cancer
Epilepsy
Neuropilin-2 precursor (isoform 2)O60462
Cancer
Neuropilin-2 precursor (isoform 1)O60462
Cancer
Neuropilin 1O14786
Cancer
Neuropeptide Y receptor type 4P50391
Cancer
Diabetes
Neuropeptide Y receptor type 2P49146
Diabetes
Cancer
Epilepsy
Neuropeptide Y receptor type 1 (NPY1-R)P25929
DiabetesCancer
Neuropeptide S receptor isoform BQ6W5P4
Cancer
Neuropeptide S receptor isoform AQ6W5P4
Cancer
Neuropeptide FF receptor 2 isoform 1Q9Y5X5
Diabetes
Cancer
Neuronal acetylcholine receptor subunit alpha-7 precursor (isoform 1)P36544
Cancer
Epilepsy
Diabetes
Neuronal acetylcholine receptor subunit alpha-4 isoform 1 precursorP43681
Cancer
Epilepsy
Neuromedin-K receptorP29371
Cancer
Neuromedin-B receptorP28336
Cancer
Neurogenic locus notch homolog protein 3 precursorQ9UM47
Cancer
Neurogenic locus notch homolog protein 2 preproproteinQ04721
Cancer
Neurogenic locus notch homolog protein 1P46531
Cancer
Neurogenic locus notch homolog protein 1 preproproteinP46531
Cancer
Neuregulin 1 (isoform alpha 1)Q02297
Cancer
Neural cell adhesion molecule 1 precursor (isoform 1)P13591
Cancer
NeprilysinP08473
Cancer
Epilepsy
NEDD8-activating enzyme E1
Cancer
NDC80 kinetochore complex
Cancer
Natural resistance-associated macrophage protein 2 (isoform 1)P49281
Cancer
N-arachidonyl glycine receptorQ14330
Cancer
NADPH oxidase isoform NOH-1LQ9Y5S8
Cancer
NADPH Oxidase Complex
Cancer
Diabetes
NADPH oxidase 4Q9NPH5
Diabetes
Cancer
NADPH oxidase 3Q9HBJ9
DiabetesCancer
NADPH oxidase 1 (NOH-1Lv isoform)Q9Y5S8
Cancer
NADPH Oxidase (nonspecified subtype)
CancerDiabetes
NAD-dependent protein deacetylase sirtuin-1 isoform aQ96EB6
DiabetesCancer
NAD-dependent deacetylase sirtuin-5 (isoform 3)Q9NXA8
Cancer
Diabetes
NAD-dependent deacetylase sirtuin-5 (isoform 2)Q9NXA8
Cancer
Diabetes
NAD-dependent deacetylase sirtuin-5 (isoform 1)Q9NXA8
Cancer
Diabetes
NAD-dependent deacetylase sirtuin-3, mitochondrial (isoform a)Q9NTG7
Cancer
NAD-dependent deacetylase sirtuin-2 (isoform 1)Q8IXJ6
Cancer
Diabetes
NAD+ ADP-Ribosyltransferase (poly(ADP-ribose)polymerase; PARP) (nonspecified subtype)
Cancer
Diabetes
Epilepsy
NAD(P)H dehydrogenase [quinone] 1 (isoform a)P15559
Diabetes
Cancer
N-acylaminoacyl-peptide hydrolaseP13798
Cancer
Na+/K+-ATPase (nonspecified subtype)
CancerLeishmaniasis
Na+/H+ Exchanger (NHE) (nonspecified subtype)
Cancer
Malaria
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1)O94760
Cancer
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (isoform 2)O94760
Cancer
Myosin-light-chain kinase (MLCK)Q15746
Cancer
Myosin-2Q9UKX2
Cancer
Myeloperoxidase (MPO)P05164
Cancer
Myeloid differentiation primary response protein (88)Q99836
Cancer
Myeloid cell surface antigen CD33 precursor (isoform 1)P20138
Cancer
Myc proto-oncogene proteinP01106
CancerDiabetes
Mu-type opioid receptor (isoform MOR-1X)P35372
Cancer
Diabetes
Epilepsy
Mu-type opioid receptor (isoform MOR-1)P35372
CancerDiabetes
Epilepsy
Muscarinic Acetylcholine Receptor M5P08912
Cancer
Muscarinic acetylcholine receptor M4P08173
Cancer
Muscarinic acetylcholine receptor M3P20309
Diabetes
Epilepsy
Cancer
Muscarinic acetylcholine receptor M1P11229
EpilepsyCancerDiabetes
Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype)
CancerDiabetesEpilepsy
Multidrug resistance-associated protein 1P33527
CancerDiabetes
Multidrug resistance protein 1 (MDR-1)P08183
Cancer
Diabetes
Epilepsy
Mucosa associated lymphoid tissue lymphoma translocation protein 1 (isoform a)Q9UDY8
Cancer
Mucin-1 (isoform 1)P15941
Cancer
Mucin 16Q8WXI7
Cancer
Mucin (nonspecified subtype)
Cancer
Diabetes
mu-Calpain (calpain 1)
Epilepsy
Cancer
mTOR complex 2
CancerEpilepsy
mTOR complex 1
CancerDiabetes
Malaria
Epilepsy
MreB
Cancer
M-phase inducer phosphatase 1 isoform aP29473
Cancer
Motilin receptorO43193
Cancer
Monoglyceride lipase (isoform 2)Q99685
CancerEpilepsy
Monoglyceride lipase (isoform 1)Q99685
CancerEpilepsy
Monocarboxylate transporter 4O15427
Cancer
Monocarboxylate transporter 2O60669
Cancer
Monocarboxylate transporter 1P53985
CancerDiabetes
Monoacylglycerol lipase ABHD12 (isoform b)Q8N2K0
Leishmaniasis
Cancer
Monoacylglycerol lipase ABHD12 (isoform a)Q8N2K0
Leishmaniasis
Cancer
MLL1/MLL Complex
Cancer
Mitogen-activated protein kinase p38 alpha (MAPK p38 alpha Exip form)Q16539
CancerDiabetes
Mitogen-activated protein kinase p38 alpha (MAPK p38 alpha CSBP1 isoform)Q16539
CancerDiabetes
Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype)
Cancer
Epilepsy
Diabetes
Mitogen-activated protein kinase kinase kinase kinase 4 (isoform 4)O95819
Cancer
Diabetes
Mitogen-activated protein kinase kinase kinase kinase 4 (isoform 2)O95819
Cancer
Diabetes
Mitogen-activated protein kinase kinase kinase kinase 4 (isoform 1)O95819
Cancer
Diabetes
Mitogen-activated protein kinase kinase kinase kinase 2Q12851
Cancer
Mitogen-activated protein kinase kinase kinase 9 (isoform 1)P80192
Cancer
Mitogen-activated protein kinase kinase kinase 8P41279
Diabetes
Cancer
Mitogen-activated protein kinase kinase kinase 7 (isoform B)O43318
Cancer
Mitogen-activated protein kinase kinase kinase 14Q99558
Cancer
Mitogen-activated protein kinase kinase kinase 11Q16584
Cancer
Diabetes
Epilepsy
Mitogen-activated protein kinase kinase kinase 10Q02779
Cancer
Mitogen-activated protein kinase 9 (isoform JNK2 alpha2)P45984
Cancer
Diabetes
Mitogen-activated protein kinase 9 (isoform JNK2 alpha1)P45984
Cancer
Diabetes
Mitogen-activated protein kinase 8 (isoform 2)
DiabetesCancer
Mitogen-activated protein kinase 8 (isoform 1)P45983
DiabetesCancer
Mitogen-activated protein kinase 7Q13164
Cancer
Mitogen-activated protein kinase 3 (isoform 1)P27361
CancerDiabetes
Mitogen-activated protein kinase 11Q15759
CancerDiabetes
Mitogen-activated protein kinase 1P28482
CancerDiabetes
Mitogen-Activated Protein Kinase (MAP Kinase)-Activated Protein Kinase (nonspecified subtype)
CancerDiabetes
Mitogen-activated protein kinase (JNK) (nonspecified subtype)
DiabetesCancer
Epilepsy
Mitochondrial uncoupling protein 2P55851
Diabetes
Cancer
Mitochondrial import inner membrane translocase subunit TIM16Q9Y3D7
Cancer
Mineralocorticoid receptor isoform 1P08235
CancerDiabetes
MidkineP21741
Cancer
Microtubule-associated protein 4 (isoform 1)P27816
Cancer
MHC class I chain-related protein AQ29983
Cancer
Methylated-DNA-protein-cysteine methyltransferase (MGMT)P16455
Cancer
Methionyl aminopeptidase 2 (MetAP2)P50579
Cancer
Diabetes
Malaria
Methionyl aminopeptidase 1P53582
Cancer
Malaria
Methionine adenosyltransferase (nonspecified subtype)
Cancer
Metalloreductase STEAP1Q9UHE8
Cancer
Metabotropic glutamate receptor 5 precursor (isoform b)P41594
Diabetes
Cancer
Epilepsy
Metabotropic glutamate receptor 4 precursorQ14833
Cancer
Diabetes
Epilepsy
Metabotropic glutamate receptor 3 precursorQ14832
Cancer
Epilepsy
Metabotropic glutamate receptor 2 precursor (isoform a)Q14416
EpilepsyDiabetes
Cancer
Metabotropic glutamate receptor 1 precursor (isoform alpha)Q13255
Cancer
Epilepsy
Metabotropic glutamate (mGluR) receptor (nonspecified subtype)
Epilepsy
Mesothelin preproprotein (isoform 2)Q13421
Cancer
Membrane-bound transcription factor site-1 proteaseQ14703
Cancer
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (isoform 1)Q99640
Cancer
Membrane-associated progesterone receptor component 1O00264
CancerEpilepsy
Melatonin Receptor type 1A (Mel1A)P48039
Diabetes
Cancer
Epilepsy
Melanoma-associated antigen 3P43357
Cancer
Melanocyte-stimulating hormone receptorQ01726
DiabetesCancer
Melanocortin receptor 4P32245
Diabetes
Cancer
Melanin-concentrating hormone receptor 1Q99705
Diabetes
Cancer
Matrix metalloproteinase-16 isoform 1 preproproteinP51512
Cancer
Matrix metalloproteinase 14 (MMP-14)P50281
Cancer
Matrix Metalloproteinase (MMP) (nonspecified subtype)
DiabetesCancer
Matrilysin (MMP-7)P09237
Cancer
Maternal embryonic leucine zipper kinaseQ14680
Cancer
Mast/stem cell growth factor receptor Kit (c-Kit)P10721
Cancer
Diabetes
MAP kinase-interacting serine/threonine-protein kinase 2 (isoform 2)Q9HBH9
Diabetes
Cancer
MAP kinase-interacting serine/threonine-protein kinase 2 (isoform 1)Q9HBH9
Diabetes
Cancer
MAP kinase-interacting serine/threonine-protein kinase 1 (isoform 2)Q9BUB5
CancerDiabetes
MAP kinase-interacting serine/threonine-protein kinase 1 (isoform 1)Q9BUB5
CancerDiabetes
MAP Kinase-Interacting Serine/Threonine-Protein Kinase (nonspecified subtype)
Diabetes
Cancer
MAP kinase-activated protein kinase 2 (isoform 2)P49137
Cancer
MAP kinase-activated protein kinase 2 (isoform 1)P49137
Cancer
MANSC domain-containing protein 1 precursorQ9H8J5
Cancer
Mannose-6-phosphate isomeraseP34949
Cancer
Malate dehydrogenase, mitochondrialP40926
Cancer
Macrophage-stimulating protein receptor (isoform 1)Q04912
Cancer
Macrophage Migration Inhibitory Factor (MIF)P14174
CancerMalaria
Diabetes
Macrophage metalloelastaseP39900
Cancer
Macrophage colony-stimulating factor 1 receptor (CSF-1R)P07333
Cancer
Diabetes
Lysyl oxidase-like 2Q9Y4K0
Cancer
Lysosomal-associated membrane protein 1P11279
Cancer
Lysosomal acid lipase/cholesteryl ester hydrolaseP38571
Diabetes
Cancer
Lysophospholipid edg6 (S1P4) receptorO95977
Cancer
Lysophospholipid (edg) Receptors (nonspecified subtype)
Cancer
Lysophosphatidic acid receptor 3Q9UBY5
Cancer
Lysophosphatidic acid receptor 2Q9HBW0
Cancer
Lysophosphatidic acid receptor 1Q92633
Cancer
Lysine-specific histone demethylase 1BQ8NB78
Cancer
Lysine-specific histone demethylase 1 (isoform a)O60341
CancerMalaria
Epilepsy
Lysine-specific demethylase 7Q6ZMT4
Cancer
Lysine-specific demethylase 6AO15550
Cancer
Lysine-specific demethylase 5CP41229
Cancer
Lysine-specific demethylase 5AP29375
Cancer
Lysine-specific demethylase 4EB2RXH2
Cancer
Lysine-specific demethylase 4DQ6B0I6
Cancer
Lysine-specific demethylase 4C (isoform 1)Q9H3R0
Cancer
Lysine-specific demethylase 4BO94953
Cancer
Lysine-specific demethylase 4AO75164
Cancer
Lysine-specific demethylase 2AQ9Y2K7
Cancer
Lysine (K)-specific demethylase 6BO15054
Cancer
Lymphokine-activated killer T-cell-originated protein kinaseQ96KB5
Cancer
Lymphocyte-activation protein 3P18627
Cancer
Lymphocyte antigen 75O60449
Cancer
Lymphocyte antigen 6EQ16553
Cancer
Lupus La proteinP05455
Cancer
L-type voltage-dependent calcium channel complex
Cancer
Epilepsy
Diabetes
L-Type calcium channel (nonspecified subtype)
Epilepsy
Cancer
DiabetesMalaria
L-selectin precursorP14151
Cancer
Low-density lipoprotein receptor precursor (isoform 1)P01130
CancerLeishmaniasis
Diabetes
Low molecular weight phosphotyrosine protein phosphataseP24666
Diabetes
Cancer
Low density lipoprotein receptor-related protein 6O75581
Cancer
Low affinity immunoglobulin gamma Fc region receptor III-A precursor (isoform a)P08637
Cancer
Low affinity immunoglobulin gamma Fc region receptor II-b isoform 1 precursorP31994
Cancer
Liver X Receptor (nonspecified subtype)
CancerDiabetes
Lipoxygenase (nonspecified subtype)
Leishmaniasis
Diabetes
Cancer
Epilepsy
Lipolysis-stimulated lipoprotein receptor (isoform 2)Q86X29
Cancer
LIM domain kinase 2 (isoform 1)P53671
Cancer
LIM domain kinase 1 (isoform 1)P53667
Cancer
Leukotriene-A4 hydrolaseP09960
Cancer
Leukotriene B4 receptor 2Q9NPC1
Cancer
Leukotriene B4 receptor (LTB4-R) (nonspecified subtype)
Diabetes
Cancer
Leukocyte surface antigen CD47 isoform 1 precursorQ08722
Cancer
Leukemia inhibitory factor (LIF) (isoform 2)P15018
Cancer
Leukemia inhibitory factor (LIF) (isoform 1)P15018
Cancer
Leucyl-cystinyl aminopeptidase (isoform 2)Q9UIQ6
Cancer
Leucyl-cystinyl aminopeptidase (isoform 1)Q9UIQ6
Cancer
Leucine-rich repeat-containing protein 15Q8TF66
Cancer
Leucine-rich repeat serine/threonine-protein kinase 2Q5S007
Cancer
Leucine-rich repeat serine/threonine-protein kinase 1Q38SD2
Cancer
Leucine rich repeat containing 32Q14392
Cancer
Leptin receptor (OB-R) (isoform 2)P48357
DiabetesCancer
Leptin receptor (OB-R) (isoform 1)P48357
DiabetesCancer
LegumainQ99538
Cancer
Lck kinaseP06239
CancerDiabetes
Large neutral amino acids transporter small subunit 1Q01650
Cancer
Large envelope proteinP03138
Cancer
Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype)
Diabetes
Epilepsy
Cancer
Lanosterol synthase (isoform 1)P48449
Cancer
Lactoylglutathione lyaseQ04760
Cancer
Lactotransferrin isoform 1 precursorP02788
Cancer
Lactate dehydrogenase AP00338
CancerMalaria
Lactate Dehydrogenase (nonspecified subtype)
CancerEpilepsy
Kv7.3O43525
Epilepsy
Cancer
Kruppel-like factor 10 (isoform a)Q13118
Cancer
KRR1 small subunit processome component homologQ13601
Cancer
KiSS-1 receptorQ969F8
CancerDiabetes
KiSS-1 metastasis-suppressorQ15726
CancerDiabetes
Kinesin-like protein KIF11P52732
Cancer
Killer cell immunoglobulin-like receptor,two domains, long cytoplasmic tail, 3 (isoform 2;(KIR-2DL3)P43628
Cancer
Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR-2DL1)P43626
Cancer
Killer cell immunoglobulin-like receptor 2DL2 precursorP43627
Cancer
Kidney-associated antigen 1Q9UBP8
Cancer
Keratin, type I cytoskeletal 19P08727
Cancer
Kelch-like ECH-associated protein 1 (isoform 2)Q14145
Diabetes
Cancer
Kelch-like ECH-associated protein 1 (isoform 1)Q14145
Diabetes
Cancer
KDM5A-GATAD1-EMSY chromatin complex
Cancer
KCNQ Channels (K(v) 7) (nonspecified subtype)
CancerEpilepsy
kappa-Opioid (KOP) receptorP41145
CancerDiabetes
Epilepsy
Malaria
Kallikrein-7P49862
Cancer
Kallikrein-5Q9Y337
Cancer
Kallikrein-4Q9Y5K2
Cancer
Kallikrein-2 isoform 3P20151
Cancer
Kallikrein-2 isoform 2 preproproteinP20151
Cancer
Kallikrein-2 isoform 1 preproproteinP20151
Cancer
Kallikrein (nonspecified subtype)
Cancer
Kainate Receptor (GluR) (nonspecified subtype)
Epilepsy
K(ATP) Channel (nonspecified subtype)
DiabetesCancer
Jun B proto-oncogeneP17275
Cancer
Diabetes
Jumonji, AT rich interactive domain 1BQ9UGL1
Cancer
Janus Kinase (nonspecified subtype)
CancerDiabetes
Jagged-2Q9Y219
Cancer
Jagged 1P78504
Cancer
Isocitrate dehydrogenase 1 (NADP+), solubleO75874
CancerDiabetes
Isocitrate dehydrogenase [NADP], mitochondrialP48735
Cancer
Invariant T Cell Receptor
Cancer
Intestinal-type alkaline phosphatase (IAP) precursorP09923
Cancer
Intermediate conductance calcium-activated potassium channel protein 4O15554
Cancer
Interleukin-9 precursorP15248
Cancer
Interleukin-3 receptor subunit alpha isoform 1 precursorP26951
Cancer
Interleukin-23 subunit alphaQ6NZ80
Cancer
Interleukin-20Q9NYY1
Cancer
Interleukin-2 receptor subunit alphaP01589
CancerDiabetes
Interleukin-17 receptor A (isoform 2)Q96F46
DiabetesCancer
Interleukin-13 receptor subunit alpha-1P78552
Cancer
Interleukin-13 receptor subunit alpha-1 (isoform X1)P78552
Cancer
Interleukin-12 (IL-12)
CancerDiabetes
Epilepsy
Interleukin-10 receptor subunit alphaQ13651
Cancer
Interleukin-10 precursorP22301
Cancer
Leishmaniasis
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)O43187
Cancer
Diabetes
Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4)Q9NWZ3
Cancer
Interleukin-1 receptor-associated kinase (IRAK) (nonspecified subtype)
Cancer
Diabetes
Interleukin-1 receptor type 2 precursorP27930
Diabetes
Cancer
Interleukin-1 receptor type 1 precursorP14778
Diabetes
Cancer
Interleukin-1 receptor antagonist protein (isoform 4)P18510
Cancer
Diabetes
Interleukin-1 receptor antagonist protein (isoform 3)P18510
Cancer
Diabetes
Interleukin-1 receptor antagonist protein (isoform 2)P18510
DiabetesCancer
Interleukin-1 receptor antagonist protein (isoform 1)P18510
DiabetesCancer
Interleukin-1 receptor accessory protein precursor (isoform 1)Q9NPH3
Cancer
Interleukin-1 betaP01584
Cancer
Diabetes
Schistosomiasis
Epilepsy
Malaria
Interleukin-1 (nonspecified subtype)
DiabetesCancer
Interleukin 6 (IL-6)P05231
Cancer
Diabetes
EpilepsyMalaria
Interleukin 23 (IL-23)
Cancer
Interleukin 21Q9HBE4
Diabetes
Interleukin 2 (IL-2)P60568
Cancer
Diabetes
Interleukin 17 (nonspecified subtype)
Cancer
Diabetes
Interleukin 13 (IL-13)P35225
Cancer
Diabetes
Interleukin 1 alpha proproteinP01583
Diabetes
Cancer
Interferon-induced helicase C domain-containing protein 1Q9BYX4
Cancer
Interferon-alpha (IFN-alpha) (nonspecified subtype)
Cancer
Diabetes
Interferon gamma receptor 2P38484
Cancer
Interferon gamma receptor 1P15260
Cancer
Interferon gamma precursorP01579
Cancer
Diabetes
Interferon alpha-1/13 precursorP01562

Cancer
Interferon alpha/beta receptor 2 precursor (isoform b)P48551
Cancer
Interferon alpha/beta receptor 1 precursorP17181
Cancer
Intercellular adhesion molecule 1P05362
Cancer
Integrin Receptor (nonspecified subtype)
Cancer
Integrin beta-3P05106
Cancer
Integrin beta-2P05107
Cancer
Integrin alphavbeta6 receptor
Cancer
Integrin alphavbeta5 receptor
Cancer
Integrin alphavbeta1
Diabetes
Cancer
Integrin alphaMbeta2 (MAC-1) Receptor
Cancer
Integrin alpha-M precursor (isoform 1)P11215
Cancer
Integrin alphaLbeta2 (LFA-1) receptor
Diabetes
Cancer
Integrin alphaIIbbeta3 (fibrinogen gpIIb/IIIa) receptor
Cancer
Integrin alpha-8/beta-1 receptor
Cancer
Integrin alpha6beta4 receptor
Cancer
Integrin alpha5beta1 (VLA-5) receptor
Cancer
Integrin alpha4beta7 (LPAM-1) receptor
Cancer
Diabetes
Integrin alpha4beta1 (VLA-4) receptor
Cancer
Diabetes
Integrin alpha3beta1 receptor
Cancer
Integrin alpha2beta3 Receptor
Cancer
Integrin alpha2beta1 (VLA-2) receptor
Cancer
Integrin alpha1beta1 (VLA-1) receptor
Cancer
Integrin alpha 3 (isoform a)P26006
Cancer
Insulin-like growth factor-binding protein 2 precursorP18065
Cancer
Insulin-like growth factor II isoform 1 preproproteinP01344
Cancer
Insulin-like growth factor 2 receptorP11717
Cancer
Diabetes
Insulin-like growth factor 1 receptor precursorP08069
CancerDiabetes
Insulin-like growth factor 1 preproprotein (isoform 1)P05019
Cancer
Insulin receptor (isoform 2)P06213
Cancer
Diabetes
Insulin receptor (isoform 1)P06213
Cancer
Diabetes
Insulin preproproteinP01308
Cancer
Diabetes
Epilepsy
Inositol 1,4,5-trisphosphate receptor type 1 (isoform 2)Q14643
Cancer
Inosine-5'-monophosphate dehydrogenase 2P12268
Cancer
Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype)
Cancer
INO80 complex
Cancer
Inhibitory kappaB Kinase (IKK) (nonspecified subtype)
Cancer
Diabetes
Inhibitor of nuclear factor kappa-B kinase subunit beta (isoform 1)O14920
Diabetes
Cancer
Inhibitor of nuclear factor kappa-B kinase subunit alphaO15111
DiabetesCancer
Inhibitor of Apoptosis Proteins (IAPs) (nonspecified subtype)
Cancer
Inhibin beta A chainP08476
Cancer
Inflammasome
CancerDiabetes
Epilepsy
Inducible T-cell co-stimulatorQ9Y6W8
Cancer
Induced myeloid leukemia cell differentiation protein Mcl-1 (isoform 1)Q07820
Cancer
Indoleamine 2,3-dioxygenase 1P14902
CancerDiabetes
Inactive tyrosine-protein kinase transmembrane receptor ROR1Q01973
Cancer
Inactive tyrosine-protein kinase 7 (PTK7)Q13308
Cancer
Inactive caspase-12Q6UXS9
Cancer
Importin subunit beta-1Q14974
Cancer
Importin alpha-7/beta-1
Cancer
Immunoproteasome
MalariaCancer
Immunoglobulin-like domain containing receptor 2Q71H61
Cancer
Immunoglobulin heavy constant epsilon (IgE)P01854
Cancer
Diabetes
Imidazoline I3 receptor (I3)
CancerDiabetes
IL-6 receptor
DiabetesCancer
IL-6 receptor alpha (isoform 1)P08887
DiabetesCancer
IL-4 receptor
DiabetesCancer
IL-3 receptor
Cancer
IL-23 receptor
Cancer
IL-20 receptor
Cancer
IL-2 receptor
CancerDiabetes
IL-17 receptor A (isoform 1)Q96F46
DiabetesCancer
IL-17 Receptor (nonspecified subtype)
Cancer
IL-15 receptor
Cancer
IL-13 receptor
Cancer
IL-1 receptor-associated kinase 1 (IRAK1)P51617
CancerDiabetes
IKK-related kinase epsilon (IKK-E)Q14164
DiabetesCancer
I-kappa-B-kinase (IKK) complex
Cancer
Diabetes
IgG receptor FcRn large subunit p51 precursorP55899
Cancer
IgE Receptors (nonspecified subtype)
Cancer
Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype)
CancerDiabetes
Hypoxanthine phosphoribosyltransferase 1P00492
Malaria
Cancer
Hydroxysteroid (17-beta) dehydrogenase 3P37058
Cancer
Hydroxymethylglutaryl-CoA reductase (NADPH) (isoform 1)P04035
Cancer
Diabetes
Malaria
Epilepsy
Leishmaniasis
Hydroxycarboxylic acid receptor 2Q8TDS4
Diabetes
Cancer
Homeodomain-interacting protein kinase 1 (isoform 1)Q86Z02
Cancer
HLA class II histocompatibility antigen, DRB1-1 beta chainP04229
Cancer
HLA class II histocompatibility antigen, DR beta 5 chainQ30154
Cancer
HLA class II histocompatibility antigen, DR beta 3 chainP79483
Cancer
HLA class II histocompatibility antigen, DR alpha chainP01903
Cancer
HLA class II histocompatibility antigen, DR (HLA-DR)
Cancer
HLA Class II Histocompatibility Antigen, DQ8
DiabetesCancer
HLA class II histocompatibility antigen gamma chainP04233
Cancer
HLA Class I Histocompatibility Complex, A (nonspecified subtype)
Cancer
HLA class I histocompatibility antigen, A-2 alphaP01892
Cancer
Histone-lysine N-methyltransferase, H3 lysine-79 specificQ8TEK3
Cancer
Histone-lysine N-methyltransferase SUV39H1O43463
Cancer
Histone-lysine N-Methyltransferase SMYD3Q9H7B4
Cancer
Histone-lysine N-methyltransferase SETD7Q8WTS6
Cancer
Histone-lysine N-methyltransferase SETD2Q9BYW2
Cancer
Histone-lysine N-methyltransferase NSD2O96028
Cancer
Histone-lysine N-methyltransferase KMT5BQ4FZB7
Cancer
Histone-lysine N-methyltransferase EZH2 isoform cQ15910
Cancer
Histone-lysine N-methyltransferase EZH2 (isoform d)Q15910
Cancer
Histone-lysine N-methyltransferase EZH2 (isoform a)Q15910
Cancer
Histone-lysine N-methyltransferase EZH1Q92800
Cancer
Histone-lysine N-methyltransferase 2A precursor (isoform 2)Q03164
Cancer
Histone-lysine N-methyltransferase 2A isoform 1 precursorQ03164
Cancer
Histone-arginine methyltransferase CARM1Q86X55
Cancer
Leishmaniasis
Histone methyltransferase (nonspecified subtype)
Cancer
Histone Lysine Demethylase (nonspecified subtype)
Cancer
Histone deacetylase 9 (isoform 3)Q9UKV0
Diabetes
Cancer
Histone deacetylase 8Q9BY41
Leishmaniasis
Diabetes
Cancer
Histone deacetylase 7 (isoform a)Q8WUI4
Cancer
Histone deacetylase 6 (HDAC6)Q9UBN7
CancerMalaria
Diabetes
Leishmaniasis
Histone deacetylase 5 (isoform 3)Q9UQL6
Cancer
Histone deacetylase 4P56524
CancerDiabetes
Histone deacetylase 3O15379
CancerDiabetes
Histone deacetylase 2 (HDAC2)Q92769
CancerDiabetes
Histone deacetylase 11Q96DB2
Cancer
Histone deacetylase 10Q969S8
Cancer
Histone deacetylase 1 (HDAC1)Q13547
Cancer
Epilepsy
Diabetes
Histone deacetylase (nonspecified subtype)
Epilepsy
Cancer
Malaria
Leishmaniasis
Diabetes
Histone acetyltransferase p300Q09472
SchistosomiasisCancer
Histone acetyltransferase KAT5Q92993
Cancer
Histone acetyltransferase KAT2BQ92831
Schistosomiasis
Cancer
Histone acetyltransferase KAT2AQ92830
SchistosomiasisCancer
Histone acetyltransferase (HAT) (nonspecified subtype)
Cancer
Schistosomiasis
Histidine decarboxylaseP19113
Cancer
Histamine Receptor (HR) (nonspecified subtype)
Cancer
Epilepsy
High mobility group box protein 1 (HMGB1)P09429
Cancer
Diabetes
High affinity nerve growth factor receptor (Trk-A) (isoform 3)P04629
Cancer
High affinity nerve growth factor receptor (Trk-A) (isoform 2)P04629
Cancer
High affinity immunoglobulin gamma Fc receptor I (CD64)P12314
Cancer
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A precursor (isoform a)Q13946
Cancer
Leishmaniasis
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (isoform c)Q13946
Cancer
Leishmaniasis
Hexokinase 2P52789
Cancer
HER (erbB) (nonspecified subtype)
Cancer
Hepatoma-derived growth factor (high-mobility group protein 1-like)P51858
Cancer
Hepatocyte nuclear factor 4-alpha (isoform b)P41235
Cancer
Diabetes
Hepatocyte growth factor receptor precursor (isoform b)P08581
CancerDiabetes
Ribosomal protein S6 kinase alpha-3P51812
Cancer
Diabetes
Ribosomal protein S6 kinase alpha-4 (isoform a)O75676
Diabetes
Cancer
Ribosomal protein S6 kinase beta-1P23443
CancerDiabetes
Ribosomal Protein S6 Kinase, 70kDa (p70S6K) (nonspecified subtype)
CancerDiabetes
Ribosomal Protein S6 Kinase, 90kDa (nonspecified subtype)
Cancer
RNA polymerase (viral)
Cancer
RNA-binding protein EWS isoform 2
Cancer
RNA-binding protein Musashi homolog 1
Cancer
Runt-related transcription factor 1 (isoform a)Q01196
Cancer
Diabetes
Runt-related transcription factor 1 (isoform b)Q01196
Cancer
Diabetes
Runt-related transcription factor 1 isoform AML1aQ01196
Cancer
Diabetes
Runt-related transcription factor 2 (isoform a)Q13950
Cancer
Diabetes
Runt-related transcription factor 2 (isoform c)Q13950
Cancer
Diabetes
Runt-related transcription factor 3 (isoform 1)Q13761
Cancer
Diabetes
Runt-related transcription factor 3Q13761
Cancer
Diabetes
S100 Calcium Binding Protein (nonspecified subtype)
Cancer
S100 calcium binding protein A9
Cancer
S-adenosylmethionine decarboxylase proenzyme (isoform 1)
Cancer
Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase (SERCA) (nonspecified subtype)
Cancer
Diabetes
Scavenger receptor class B member 1 (isoform 1)
Cancer
Scavenger receptor class B member 1 (isoform 2)
Cancer
Semaphorin 4D (isoform 1)
Cancer
Semaphorin-4D (isoform 2)
Cancer
Sentrin-specific protease 1
Cancer
Sentrin-specific protease 2
Cancer
Sentrin-specific protease 7
Cancer
Serine palmitoyltransferase
Cancer
Diabetes
Serine protease (nonspecified subtype)
Diabetes
Cancer
Serine protease hepsin
Cancer
Serine/Threonine Kinase (nonspecified subtype)
CancerDiabetes
Serine/threonine-protein kinase (PAK) (nonspecified subtype)
Cancer
Serine/threonine-protein kinase 33
Cancer
Serine/threonine-protein kinase 4Q13043
Diabetes
Cancer
Serine/threonine-protein kinase A-Raf isoform 1
Cancer
Serine/threonine-protein kinase ATR
Cancer
Serine/threonine-protein kinase Chk1 (isoform 1)O14757
CancerDiabetes
Serine/threonine-protein kinase Chk2 (isoform a)
Cancer
Serine/threonine-protein kinase D1
Cancer
Serine/threonine-protein kinase D3
Cancer
Serine/threonine-protein kinase MRCK alpha (isoform B)
Cancer
Serine/threonine-protein kinase MRCK beta
Cancer
Serine/threonine-protein kinase mTORP42345
CancerMalaria
Diabetes
Epilepsy
Serine/threonine-protein kinase Nek1
Cancer
Serine/threonine-protein kinase Nek2 (isoform 1)
Cancer
Serine/threonine-protein kinase PAK 1 (isoform 1)
Cancer
Serine/threonine-protein kinase PAK 1 isoform 2
Cancer
Serine/threonine-protein kinase PAK 2
Cancer
Serine/threonine-protein kinase PAK 4 (isoform 1)
Cancer
Serine/threonine-protein kinase PAK 4 (isoform 2)
Cancer
Serine/threonine-protein kinase PAK 6
Cancer
Serine/threonine-protein kinase PAK 7
Cancer
Serine/threonine-protein kinase PLK2
Cancer
Serine/threonine-protein kinase PLK3
Cancer
Serine/threonine-protein kinase PLK4
Cancer
Serine/threonine-protein kinase receptor R3 precursor
Cancer
Serine/threonine-protein kinase Sgk1 (isoform 1)O00141
DiabetesCancer
Serine/threonine-protein kinase TBK1Q9UHD2
CancerDiabetes
Serine/threonine-protein kinase ULK1
Cancer
Serine/threonine-protein kinase ULK2
Cancer
Serine/threonine-protein kinase/endoribonuclease IRE1O75460
DiabetesCancer
Serine-protein kinase ATM
Cancer
Serotonin receptor (5-HT3 receptor) (nonspecified subtype)
Cancer
Serotonin Receptor (nonspecified subtype)
Epilepsy
SFRS protein kinase 1
Cancer
Sialyltransferase (nonspecified subtype)
Cancer
Sigma non-opioid intracellular receptor 1 (isoform 1)Q99720
Leishmaniasis
Malaria
Cancer
Epilepsy
sigma Receptor (nonspecified subtype)
Epilepsy
Cancer
Signal transducer and activator of transcription 5B
Cancer
Signal transducer and activator of transcription 6 (isoform 1)
Cancer
Small Conductance Calcium-Activated Potassium Channel (SK) (nonspecified subtype)S
Cancer
Epilepsy
Small conductance calcium-activated potassium channel protein 3 (isoform a)Q9UGI6
Cancer
Epilepsy
Diabetes
S-Methyl-5-thioadenosine phosphorylase
Cancer
Smoothened homologQ99835
CancerDiabetes
SMT3 suppressor of mif two 3 homolog 1 (isoform a)
Cancer
Sodium- and chloride-dependent creatine transporter 1
Cancer
Sodium channel (nonspecified subtype)
Cancer
Epilepsy
Diabetes
Malaria
Sodium channel protein type 1 subunit alpha (isoform 1)P35498
Epilepsy
Sodium channel protein type 1 subunit alpha (isoform 2)P35498
Epilepsy
Sodium channel protein type 2 subunit alpha (Nav1.2)Q99250
Epilepsy
Sodium channel protein type 5 subunit alpha (Nav1.5) (isoform a)Q14524
Epilepsy
Cancer
Diabetes
Sodium channel protein type 5 subunit alpha (Nav1.5) (isoform b)Q14524
CancerDiabetes
Epilepsy
Sodium channel protein type 5 subunit alpha (Nav1.5) (isoform c)Q14524
DiabetesEpilepsy
Cancer
Sodium channel protein type 5 subunit alpha (Nav1.5) (isoform d)Q14524
CancerDiabetes
Epilepsy
Sodium channel protein type 9 subunit alpha (Nav1.7)Q15858
Cancer
Diabetes
Epilepsy
Sodium Channel, Nonvoltage-Gated 1
Cancer
Sodium/glucose cotransporter 1 (SGLT-1)P13866
DiabetesCancer
Sodium/hydrogen exchanger 1 (NHE-1)P19634
Cancer
Diabetes
Sodium/iodide cotransporter
Cancer
Sodium/potassium-transporting ATPase subunit alpha-1P05023
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit alpha-2P50993
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit alpha-3P13637
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit alpha-4Q13733
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit beta-1P05026
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit beta-2P14415
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit beta-3P54709
CancerLeishmaniasis
Sodium/potassium-transporting ATPase subunit gammaP54710
CancerLeishmaniasis
Sodium-dependent dopamine transporterQ01959
DiabetesEpilepsy
Sodium-dependent noradrenaline transporter (isoform 1)P23975
DiabetesEpilepsyCancer
Sodium-dependent noradrenaline transporter (isoform 2)P23975
DiabetesEpilepsyCancer
Sodium-dependent Phosphate Transport Protein 2B
Cancer
Sodium-dependent serotonin transporterP31645
DiabetesEpilepsy
Malaria
Cancer
Soluble guanylyl cyclase
DiabetesCancer
Solute carrier family 2, facilitated glucose transporter member 1
Cancer
Solute carrier family 2, facilitated glucose transporter member 3
Cancer
Solute carrier family 2, facilitated glucose transporter member 8 isoform 1
Cancer
Solute carrier family 28 member 3
Cancer
Somatostatin preproproteinP61278
CancerDiabetes
Somatostatin receptor (nonspecified subtype)
CancerDiabetes
Somatostatin receptor type 1P30872
Cancer
Somatostatin receptor type 2P30874
CancerDiabetes
Somatostatin receptor type 3P32745
CancerDiabetes
Epilepsy
Somatostatin receptor type 4P31391
Cancer
Diabetes
Somatostatin Receptor Type 5 ReceptorP35346
CancerDiabetes
Somatotropin precursor (isoform 1)P01241
CancerDiabetes
Sonic hedgehog protein
Cancer
Sp1 transcription factor
Cancer
Spermidine synthase
Cancer
S-phase kinase-associated protein 2 (isoform 1)
Cancer
S-phase kinase-associated protein 2 (isoform 2)
Cancer
Sphingomyelin phosphodiesterase 2O60906
Diabetes
Cancer
Sphingosine 1-phosphate receptor 1P21453
CancerDiabetes
Sphingosine 1-phosphate receptor 2
Cancer
Sphingosine 1-phosphate receptor 5Q9H228
Cancer
Diabetes
Sphingosine kinase (SPK; SphK) (nonspecified subtype)
Cancer
Diabetes
Sphingosine kinase 1 (SPK1) (long isoform)
Cancer
Sphingosine kinase 2 (SPK2)
Cancer
Splicing factor 3B protein complex
Cancer
Squalene synthase (isoform 1)P37268
Leishmaniasis
Cancer
Diabetes
STAT5 (nonspecified subtype)
Cancer
Steroid 17-alpha-hydroxylase/17,20 lyaseP05093
CancerDiabetes
Steroid 5-alpha-Reductase (nonspecified subtype)
CancerDiabetes
Steroid hormone receptor ERR1 isoform 1P11474
CancerDiabetes
Sterol O-acyltransferase 1 (Acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-1)
Cancer
Sterol O-acyltransferase 2
Cancer
Sterol Regulatory Element-Binding Protein (nonspecified subtype)
Diabetes
Cancer
Steryl-sulfataseP08842
CancerDiabetes
Stimulator of interferon genes protein
Cancer
Stromal cell-derived factor 1 (alpha isoform)
Cancer
Stromal cell-derived factor 1 (beta isoform)
Cancer
Stromal cell-derived factor 1 (isoform delta)
Cancer
Stromal cell-derived factor 1 (isoform gamma)
Cancer
Stromelysin-2 (MMP-10)
Cancer
Stromelysin-3 (MMP-11)
Cancer
Substance-K receptor
Cancer
Substance-P receptor (long isoform)P25103
Epilepsy
Cancer
Substance-P receptor (short isoform)P25103
Cancer
Epilepsy
Succinate-semialdehyde dehydrogenase 5A1 (isoform 1)
Cancer
Sulfiredoxin-1
Cancer
Superoxide dismutase (SOD) (nonspecified subtype)
CancerMalariaDiabetes
Superoxide dismutase [Cu-Zn]
Cancer
Suppressor of tumorigenicity 14 protein
Cancer
Surface antigen
Cancer
Synaptic vesicular amine transporterQ05940
Cancer
Diabetes
Syndecan 1
Cancer
T Cell Receptor Complex (TCR)
Cancer
Diabetes
Tachykinin Receptor (nonspecified subtype)
Cancer
Tankyrase (TRF1-Interacting Ankyrin Related ADP-ribose Polymerase) (nonspecified subtype)
Cancer
Tankyrase 1
Cancer
Tankyrase-2
Cancer
TAR DNA-binding protein 43
Cancer
TCDD-inducible poly [ADP-ribose] polymerase (PARP-7)
Cancer
T-cell lymphoma invasion and metastasis 1
Cancer
T-cell surface glycoprotein CD1a
Cancer
T-cell surface glycoprotein CD4 isoform 1 precursor
Cancer
T-cell surface glycoprotein CD8 alpha chain
Cancer
T-complex protein 1 subunit alpha
Cancer
Telomeric repeat binding factor 2, interacting protein 1
Cancer
Telomeric repeat-binding factor 1 (isoform 2)
Cancer
Telomeric repeat-binding factor 1
Cancer
Tenascin
Cancer
Teneurin-4
Cancer
TFIID Basal Transcription Factor Complex
Cancer
TGF-beta receptor type-1 (isoform 1)
Cancer
TGF-beta receptor type-2 (isoform 1)
Cancer
TGF-beta receptor type-2 (isoform 2)
Cancer
Thioredoxin-disulfide reductase (TrxR) (nonspecified subtype)
CancerSchistosomiasis
Malaria
Diabetes
Thomsen-Friedenreich Antigen (CD176)
Cancer
Threonine aspartase 1
Cancer
Threonyl-tRNA synthetaseP26639
Cancer
Malaria
Thromboxane A2 receptor isoform alpha
Cancer
Thromboxane-A synthase (isoform 1)P24557
Cancer
Diabetes
Thymidine kinase 2, mitochondrial
Cancer
Thymidine kinase, cytosolic
Cancer
Thymidine phosphorylase
Cancer
Thymidylate synthase
Cancer
Thyroid hormone receptor (nonspecified subtype)
Diabetes
Cancer
Thyroid hormone receptor betaP10828
Diabetes
Cancer
Thyrotropin receptor
Cancer
Tie Receptor (nonspecified subtype)
Cancer
Tissue alpha-L-fucosidaseP04066
Cancer
Diabetes
Tissue factor precursor (isoform 1)
Cancer
T-lymphocyte activation antigen CD80 precursorP33681
Diabetes
Toll-Like Receptor (nonspecified subtype)
Cancer
Toll-like receptor 3
Cancer
Toll-like receptor 4 (isoform C)O00206
Cancer
Diabetes
Toll-like receptor 4 (isoform D)O00206
Cancer
Diabetes
Toll-like receptor 4 precursor (isoform A)O00206
Diabetes
Cancer
Toll-like receptor 5
Cancer
Toll-like receptor 7Q9NYK1
CancerDiabetesLeishmaniasis
Malaria
Toll-like receptor 8 precursorQ9NR97
CancerDiabetes
TRAF2 and NCK interacting kinase (isoform 1)
Cancer
Trans-acting T-cell-specific transcription factor GATA-3 (isoform 1)P23771
Cancer
Diabetes
Trans-acting T-cell-specific transcription factor GATA-3 (isoform 2)P23771
Cancer
Diabetes
Trans-acting T-cell-specific transcription factor GATA-3 (isoform X1)P23771
Cancer
Diabetes
Trans-acting T-cell-specific transcription factor GATA-3P23771
Cancer
Diabetes
Transcription activator BRG1 (isoform a)
Cancer
Transcription activator BRG1 (isoform b)
Cancer
Transcription activator BRG1 (isoform c)
Cancer
Transcription activator BRG1 (isoform f)
Cancer
Transcription Factor AP-1 (nonspecified subtype)
CancerDiabetesMalaria
Transcription factor jun-DP17535
Cancer
Diabetes
Transcription factor p65 (isoform 1)
Cancer
Transcription factor RelB
Cancer
Transcription Factor TCF (nonspecified subtype)
Cancer
Diabetes
Transcription initiation factor TFIID subunit 1 (isoform 1)
Cancer
Transcription initiation factor TFIID subunit 1 (isoform 2)
Cancer
Transcriptional activator Myb
Cancer
Transcriptional coactivator YAP1
Cancer
Transcriptional Enhancer Factor (TEAD) (nonspecified subype)
Cancer
Transcriptional intermediary factor 1-alpha (isoform a)
Cancer
Transferrin receptor
Cancer
Transforming growth factor beta (nonspecified subtype)
Cancer
Transforming growth factor beta 1 (TGF-beta1)P01137
CancerDiabetes
Transforming growth factor beta 3
Cancer
Transforming growth factor beta-2 precursor (isoform 1)
Cancer
Transforming growth factor beta-2 precursor (isoform 2)
Cancer
Transforming protein RhoA
Cancer
Transforming, acidic coiled-coil containing protein 3
Cancer
Transglutaminase (nonspecified subtype)
Cancer
Transient receptor potential cation channel subfamily A member 1 (TRPA1)O75762
Diabetes
Epilepsy
LeishmaniasisCancer
Transient receptor potential cation channel subfamily M member 3
Cancer
Transient receptor potential cation channel subfamily M member 6 (isoform a)
Cancer
Transient receptor potential cation channel subfamily M member 6 isoform b
Cancer
Transient receptor potential cation channel subfamily M member 6 isoform c
Cancer
Transient receptor potential cation channel subfamily M member 8Q7Z2W7
EpilepsyCancer
Transient receptor potential cation channel subfamily V member 1Q8NER1
EpilepsyDiabetes
Cancer
Transient receptor potential cation channel subfamily V member 3 isoform 1
Cancer
Transient receptor potential cation channel subfamily V member 6
Cancer
Transient receptor potential cation channel, subfamily C, member 6Q9Y210
Diabetes
Cancer
Transient receptor potential cation channel, subfamily M, member 7
Cancer
Transient receptor potential cation channel, subfamily V, member 2Q9Y5S1
Epilepsy
Transient receptor potential cation channel, subfamily V, member 3
Cancer
Transitional endoplasmic reticulum ATPase
Cancer
Translocator proteinP30536
Cancer
Epilepsy
Transmembrane 4 L6 family member 5 precursor
Cancer
Trifunctional purine biosynthetic protein adenosine-3 (isoform 1)
Cancer
Tripeptidyl-peptidase II
Cancer
Triple functional domain protein
Cancer
Trophoblast glycoprotein precursor
Cancer
Tropomyosin-3 (isoform 1)
Cancer
Trypanothione reductaseP28593

Malaria
Leishmaniasis
Trypsin (nonspecified subtype)
CancerDiabetes
Trypsin-1 preproproteinP07477
Cancer
Diabetes
Trypsin-2 preproproteinP07478
Diabetes
Cancer
Trypsin-3 preproprotein (isoform 2)P35030
Diabetes
Cancer
Tryptase (nonspecified subtype)
Cancer
Tryptophan 2,3-dioxygenase
Cancer
Tryptophan 5-hydroxylase 1P17752
Diabetes
Cancer
Tryptophan 5-hydroxylase 2Q8IWU9
Diabetes
Cancer
Tryptophan 5-Monooxygenase (nonspecified subtype)
Cancer
T-Type Calcium Channel
EpilepsyDiabetesCancer
Tumor endothelial marker 8 isoform 1
Cancer
Tumor necrosis factor (TNF-alpha)P01375
Leishmaniasis
Cancer
Diabetes
Schistosomiasis
Epilepsy
Malaria
Tumor necrosis factor ligand superfamily member 10 (TRAIL)
Cancer
Tumor necrosis factor ligand superfamily member 11 (RANKL)O14788
CancerDiabetes
Tumor necrosis factor ligand superfamily member 13B (BAFF)Q9Y275
Diabetes
Tumor necrosis factor ligand superfamily member 6
Cancer
Tumor necrosis factor receptor superfamily member 10A (TRAIL-R1)
Cancer
Tumor necrosis factor receptor superfamily member 10B (TRAIL-R2)
Cancer
Tumor necrosis factor receptor superfamily member 16 precursor
Cancer
Tumor necrosis factor receptor superfamily member 17
Cancer
Tumor necrosis factor receptor superfamily member 18 (isoform 2)
Cancer
Tumor necrosis factor receptor superfamily member 1A precursor
Cancer
Tumor necrosis factor receptor superfamily member 1B
Cancer
Tumor necrosis factor receptor superfamily member 25 (DR3)
Cancer
Tumor necrosis factor receptor superfamily member 4 (OX40)
Cancer
Tumor necrosis factor receptor superfamily member 5 precursor (isoform 1)
Cancer
Tumor necrosis factor receptor superfamily member 6 precursor (isoform 1)
Cancer
Tumor necrosis factor receptor superfamily member 8 (isoform 1)
Cancer
Tumor necrosis factor receptor superfamily member 9
Cancer
Tumor-associated calcium signal transducer 2 (TROP-2)
Cancer
Tumor-Associated Glycoprotein 72 (TAG-72)
Cancer
Tyk2P29597
CancerDiabetes
Type I transmembrane protein Fn14Q9NP84
CancerDiabetes
Type-1 angiotensin II receptorP30556
DiabetesCancer
TYRO3 protein tyrosine kinase
Cancer
Tyrosinase-related protein 1
Cancer
Tyrosine Kinase (nonspecified subtype)
CancerDiabetes
Malaria
Tyrosine-Protein Kinase ABL (nonspecified subtype)
CancerDiabetes
Tyrosine-protein kinase ABL1P00519
Cancer
Diabetes
Malaria
Tyrosine-protein kinase HCK precursor (isoform A)
Cancer
Tyrosine-protein kinase ITK/TSK
Cancer
Tyrosine-protein kinase JAK1P23458
CancerDiabetes
Tyrosine-protein kinase JAK2O60674
CancerDiabetes
Tyrosine-protein kinase JAK3P52333
CancerDiabetes
Tyrosine-protein kinase Lyn (isoform A)P07948
Cancer
Diabetes
Tyrosine-protein kinase receptor Tie-1P35590
Diabetes
Cancer
Tyrosine-protein kinase receptor UFO (AXL) (isoform 1)
Cancer
Tyrosine-protein kinase receptor UFO (AXL) (isoform 2)
Cancer
Tyrosine-protein kinase SYK (isoform 1)P43405
CancerDiabetes
Tyrosine-protein kinase SYK (isoform 2)P43405
CancerDiabetes
Tyrosine-protein kinase Yes
Cancer
Tyrosine-protein kinase ZAP-70P43403
Diabetes
Cancer
Tyrosine-protein phosphatase non-receptor type 13 (isoform 4)
Cancer
Tyrosine-protein phosphatase non-receptor type 2 (isoform 1)P17706
Diabetes
Cancer
Tyrosine-protein phosphatase non-receptor type 22 isoform 3Q9Y2R2
Cancer
Diabetes
Tyrosine-protein phosphatase non-receptor type 5
Cancer
Tyrosyl-DNA phosphodiesterase 1
Cancer
Tyrosyl-DNA phosphodiesterase 2 (TDP2)
Cancer
Ubiquitin carboxyl-terminal hydrolase 14 isoform a
Cancer
Ubiquitin carboxyl-terminal hydrolase 2 (isoform a)
Cancer
Ubiquitin carboxyl-terminal hydrolase 47
Cancer
Ubiquitin carboxyl-terminal hydrolase 7Q93009
CancerDiabetes
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Cancer
Ubiquitin carboxyl-terminal hydrolase L5
Cancer
Ubiquitin-conjugating enzyme E2 R1
Cancer
Ubiquitin-like domain-containing CTD phosphatase 1
Cancer
Ubiquitin-like modifier-activating enzyme 5 (isoform 1)
Cancer
UDP-N-acetylhexosamine pyrophosphorylase
Cancer
UMP kinase
Cancer
U-plasminogen activator (isoform 1)P00749
CancerDiabetes
U-plasminogen activator (isoform 2)P00749
CancerDiabetes
Uridine 5'-monophosphate synthaseP11172
CancerMalaria
Uridine phosphorylase (nonspecified subtype)
Cancer
Urokinase plasminogen activator surface receptor isoform 1 precursor
Cancer
Urokinase plasminogen activator surface receptor isoform 2 precursor
Cancer
Urotensin-2 receptorQ9UKP6
Diabetes
Cancer
Vascular cell adhesion protein 1
Cancer
Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype)
CancerDiabetesEpilepsy
Vascular endothelial growth factor receptor 1 (isoform 1)P17948
CancerDiabetes
Vascular endothelial growth factor receptor 2P35968
CancerDiabetes
Vascular endothelial growth factor receptor 3 (isoform 1)
Cancer
Vascular endothelial growth factor receptor 3 (isoform 2)
Cancer
Vascular endothelial growth factors (VEGF) (nonspecified subtype)
Cancer
Diabetes
Malaria
Vasoactive intestinal polypeptide receptor 1 (VIP-R-1)P32241
CancerDiabetes
Vasopressin V1a receptorP37288
Diabetes
Cancer
Vasopressin V2 receptorP30518
Diabetes
Cancer
Very-long-chain acyl-CoA synthetaseO14975
DiabetesCancer
Villin 2
Cancer
Vimentin
Cancer
Vitamin D receptor (VDR)P11473
CancerDiabetes
Vitamin D3 receptor (isoform VDRA)P11473
CancerDiabetes
Vitamin D3 receptor (isoform VDRB1)P11473
CancerDiabetes
Voltage-dependent L-type calcium channel subunit alpha-1C (isoform 13)Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C (isoform 17)Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C (isoform 2)Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C (isoform 3)Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C (isoform 4)Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 1Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 10Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 11Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 12Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 14Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 15Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 16Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 18Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 19Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 20Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 21Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 5Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 6Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 7Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 8Q13936
Cancer
Voltage-dependent L-type calcium channel subunit alpha-1C isoform 9Q13936
Cancer
Voltage-dependent N-type calcium channel subunit alpha-1B isoform 1Q00975
EpilepsyCancer
Voltage-dependent T-type calcium channel subunit alpha-1G isoform 1
Cancer
Voltage-dependent T-type calcium channel subunit alpha-1HO95180
CancerEpilepsy
Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype)
Cancer
Diabetes
Epilepsy
Leishmaniasis
Voltage-gated K(V) channel (nonspecified subtype)
CancerEpilepsy
Voltage-gated potassium channel beta-2 subunit (isoform 2)Q13303
CancerEpilepsy
Voltage-gated potassium channel beta-2 subunitQ13303
CancerEpilepsy
V-set domain-containing T-cell activation inhibitor 1 isoform 1 precursor
Cancer
WD repeat-containing protein 5
Cancer
Wee1-like protein kinase (isoform 1)
Cancer
Wilms tumor 1 (isoform A)
Cancer
Wilms tumor 1 (isoform B)
Cancer
Wilms tumor 1 (isoform C)
Cancer
Wilms tumor 1 (isoform D)
Cancer
Xanthine oxidaseP47989
Cancer
Diabetes
X-box binding protein 1P17861
Cancer
Diabetes
X-box-binding protein 1 isoform XBP1(S)P17861
Cancer
Diabetes
X-Chromosome-Linked Inhibitor of Apoptosis Protein (XIAP)
Cancer
Zinc transporter ZIP6
Cancer
G-protein coupled receptor 142Q7Z601
Diabetes
P2Y purinoceptor 1P47900
Diabetes
1-phosphatidylinositol-3-phosphate 5-kinase (isoform 2)Q9Y2I7
Diabetes
2-acylglycerol O-acyltransferase 2Q3SYC2
Diabetes
2-Acylglycerol O-acyltransferase 3Q86VF5
Diabetes
2-amino-3-carboxymuconate-6-semialdehydeQ8TDX5
Diabetes
Abhydrolase domain containing 6Q9BV23
Diabetes
Adhesion G protein-coupled receptor F5Q8IZF2
Diabetes
Alkaline phosphatase, tissue-nonspecific isozymeP05186
Diabetes
Alpha-galactosidase A precursorP06280
Diabetes
alpha2B-AdrenoceptorP18089
Diabetes
alpha2C-AdrenoceptorP18825
Diabetes
AMP Deaminase (nonspecified subtype)
Diabetes
Amylin receptor
Diabetes
Angiotensin-converting enzyme 2Q9BYF1
Diabetes
Apoptotic protease-activating factor 1 (isoform c)O14727
Diabetes
Aquaporin-9O43315
Diabetes
ATP-binding cassette sub-family C member 8 (ABCC8) (isoform 1)Q09428
Diabetes
ATP-binding cassette sub-family C member 8 (ABCC8) (isoform 2)Q09428
Diabetes
ATP-binding cassette sub-family C member 9 (isoform SUR2B)O60706
Diabetes
ATP-sensitive inward rectifier potassium channel 11 (isoform 1)Q14654
Diabetes
ATP-sensitive inward rectifier potassium channel 11 (isoform 2)Q14654
Diabetes
Beta-klothoQ86Z14
Diabetes
beta3-AdrenoceptorP13945
Diabetes
C-X-C motif chemokine 10 precursorP02778
Diabetes
C3a anaphylatoxin chemotactic receptorQ16581
Diabetes
Carbonic anhydrase 7 isoform 1P43166
DiabetesEpilepsy
Carnitine Palmitoyltransferase II (nonspecified subtype)
Diabetes
CD40 ligand (CD40L; CD154)P29965
Diabetes
CDGSH iron-sulfur domain-containing protein 1Q9NZ45
Diabetes
Chemokine-like receptor 1 isoform aQ99788
Diabetes
Chemokine-like receptor 1 isoform bQ5U0H0
Diabetes
Cholesterol 7-alpha-monooxygenaseP22680
Diabetes
ChymaseP23946
Diabetes
Cryptochrome (nonspecified subtype)
Diabetes
D4P21917
Diabetes
Diacylglycerol O-acyltransferase 1 (DGAT1)O75907
MalariaDiabetes
Diacylglycerol O-acyltransferase 2 (DGAT2)Q96PD7
Diabetes
Dopamine beta-monooxygenaseP09172
Diabetes
Egl nine homolog 1Q9GZT9
Diabetes
Elongation of very long chain fatty acids protein 6Q9H5J4
Diabetes
Endothelial lipase (EDL)Q9Y5X9
Diabetes
EnteropeptidaseP98073
Diabetes
Fatty Acid Binding Protein (nonspecified subtype)
Diabetes
Fatty acid binding protein 5 (psoriasis-associated)Q01469
Diabetes
Fatty acid-binding protein, heartP05413
Diabetes
Fatty acid-binding protein, intestinalP12104
Diabetes
Forkhead box O1AQ12778
Diabetes
Fructose-1,6-bisphosphatase 1P09467
Diabetes
G protein-coupled receptor 41O14843
Diabetes
Gamma-butyrobetaine dioxygenaseO75936
Diabetes
Gastric inhibitory polypeptideP09681
Diabetes
Ghrelin O-acyltransferaseQ96T53
Diabetes
GlucagonP01275
Diabetes
Glucagon receptor (GL-R)P47871
Diabetes
Glucokinase (isoform 1)P35557
Diabetes
Glucokinase regulatory proteinQ14397
Diabetes
Glutamate decarboxylase 2Q05683
Diabetes
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform 2Q06210
Diabetes
GPR139Q6DWJ6
Diabetes
Haptoglobin preproprotein (isoform 1)P00738
Diabetes
Heme Oxygenase (HO) (nonspecified subtype)
CancerDiabetes
Hepatic triacylglycerol lipase precursorP11150
Diabetes
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AO60658
Diabetes
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (isoform 1)O95263
Diabetes
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (isoform a)O76083
Diabetes
Epilepsy
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (isoform b)O76083
Diabetes
Epilepsy
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (isoform c)O76083
Diabetes
Epilepsy
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (isoform d)O76083
Diabetes
Epilepsy
Hormone-sensitive lipaseQ05469
Diabetes
Hydroxycarboxylic acid receptor 1Q9BXC0
Diabetes
Hydroxycarboxylic acid receptor 3P49019
Diabetes
IL-21 receptorQ9HBE5

Diabetes
Ileal Sodium/Bile acid CotransporterQ12908
Diabetes
Imidazoline I2 receptor (I2)
Diabetes
Imidazoline receptor (nonspecified subtype)
Diabetes
Insulin-degrading enzymeP14735
Diabetes
Interleukin-18 (isoform 1)Q14116
Diabetes
Interleukin-18 (isoform 2)Q14116
Diabetes
Islet amyloid polypeptide precursorP10997
Diabetes
Ketohexokinase (isoform b)P50053
Diabetes
LanC-like protein 2Q9NS86
Diabetes
Lanosterol 14-alpha demethylaseQ16850
Diabetes
LDL-associated phospholipase A2 (Lp-PLA2)Q13093
Diabetes
Major histocompatibility complex, class II, DR beta 4O19679
Diabetes
Mannan-binding lectin serine protease 2 (isoform 1)O00187
Diabetes
Mannan-binding lectin serine protease 2 (isoform 2)O00187
Diabetes
Melanin-concentrating hormone (MCH) receptor (nonspecified subtype)
Diabetes
Epilepsy
Melanocortin receptor (nonspecified subtype)
Diabetes
Melanocortin receptor 3 (MC3-R)P41968
Diabetes
Melanocortin receptor 5P33032
Diabetes
Melatonin Receptor type 1B (Mel1B)P49286
Diabetes
Microsomal triglyceride transfer protein large subunit precursorP55157
Diabetes
Mitochondrial brown fat uncoupling protein 1P25874
Diabetes
Mitogen-activated protein kinase 10 (isoform 2)P53779
Diabetes
Epilepsy
N-terminal kinase-like protein (isoform A)Q96KG9
Diabetes
Na+/Ca2+ Exchanger (NCX) (nonspecified subtype)
Diabetes
NACHT, LRR and PYD domains-containing protein 3 (isoform a)Q96P20
Diabetes
Epilepsy
NACHT, LRR and PYD domains-containing protein 3 (isoform e)Q96P20
Epilepsy
Diabetes
Natural cytotoxicity triggering receptor 1 (isoform a)O76036
Diabetes
Neuromedin U receptor 1Q8NE20
Diabetes
Neuromedin U receptor 2Q96AM5
Diabetes
Neuropeptide Y receptor (NPY-R) (nonspecified subtype)
Diabetes
Neuropeptide Y receptor type 5 (NPY5-R)Q15761
Diabetes
Epilepsy
Nischarin isoform 1Q9Y2I1
Diabetes
Epilepsy
NPC1-like 1Q9UHC9
Diabetes
Nuclear receptor ROR-alpha isoform aP35398
Diabetes
Nuclear receptor ROR-alpha isoform bP35398
Diabetes
Orexin receptor (nonspecified subtype)
Diabetes
Epilepsy
Orexin receptor type 1O43613
Epilepsy
Diabetes
Orexin receptor type 2O43614
Diabetes
Oxytocin-neurophysin 1 preproproteinP01178
Diabetes
P2Y purinoceptor (nonspecified subtype)
Diabetes
P2Y purinoceptor 14 (P2Y14)Q15391
Diabetes
Phosphatidylcholine:ceramide cholinephosphotransferase 2Q8NHU3
Diabetes
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2O15357
Diabetes
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial precursor (isoform 1)Q16822
Diabetes
Presenilins-associated rhomboid-like protein, mitochondrial isoform 1 preproproteinQ9H300
Diabetes
Presenilins-associated rhomboid-like protein, mitochondrial preproprotein (isoform 2)Q9H300
Diabetes
Probable G-protein coupled receptor 88 (GPR88)Q9GZN0
Diabetes
Proprotein convertase subtilisin/kexin type 9Q8NBP7
Diabetes
Receptor-type tyrosine-protein phosphatase S precursor (isoform 1)Q13332
Diabetes
Relaxin-3 receptor 2Q8TDU9
Diabetes
Retinol-binding protein 4P02753
Diabetes
Ribosomal protein S6 kinase alpha-2 (isoform a)Q15349
Diabetes
Ribosomal protein S6 kinase alpha-5O75582
Diabetes
SclerostinQ9BQB4
Diabetes
Selenoprotein S isoform 1Q9BQE4
Diabetes
Selenoprotein S isoform 2Q9BQE4
Diabetes
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoformP48454
Diabetes
SH3-containing GRB2-like protein 3-interacting protein 1Q9BQI5
Diabetes
Sn1-specific diacylglycerol lipase alphaQ9Y4D2
Diabetes
Sn1-specific diacylglycerol lipase betaQ8NCG7
Diabetes
Sodium-Glucose Cotransporter (SGLT) (nonspecified subtype)
Diabetes
Sodium/glucose cotransporter 2 (SGLT-2)P31639
Diabetes
Sodium/glucose cotransporter 3 (SGLT-3)Q9NY91
Diabetes
Soluble Phosphoenolpyruvate carboxykinase (GTP)P35558
Diabetes
Solute carrier family 13 member 5 (isoform a)Q86YT5
Diabetes
Solute carrier family 13 member 5 (isoform b)B7ZLB4
Diabetes
Solute carrier family 22 (organic anion/cation transporter) member 12Q96S37
Diabetes
Sphingosine 1-phosphate receptor 3Q99500
Diabetes
Sulfhydryl Oxidase 1 (hQSOX)O00391
Diabetes
T-lymphocyte activation antigen CD86 (isoform 1)P42081
Diabetes
Taste receptor type 1 member 2Q8TE23
Diabetes
Taste Receptor Type 1 Member 3Q7RTX0
Diabetes
TLR4/MD-2 complex
Diabetes
Trace amine associated receptor 1 (TAAR1)Q96RJ0
Diabetes
Epilepsy
Triacylglycerol Lipase (TG Lipase) (nonspecified subtype)
Diabetes
Tumor necrosis factor ligand superfamily member 4P23510
Diabetes
Tyrosine-protein phosphatase non-receptor type 9P43378
Diabetes
Uracil nucleotide/cysteinyl leukotriene receptorQ13304
DiabetesEpilepsy
Vasopressin Receptor (nonspecified subtype)
Diabetes
Vasopressin V1 Receptor (nonspecified subtype)
Diabetes
Vasopressin V1b receptorP47901
Diabetes
Epilepsy
WW domain-containing transcription regulator protein 1Q9GZV5
Diabetes
alpha-6 beta-2 Nicotinic receptor
Epilepsy
Alpha-ketoglutarate-dependent dioxygenase FTOQ9C0B1
Epilepsy
Aquaporin-4 (isoform a)P55087
Epilepsy
Aquaporin-4 (isoform b)P55087
Epilepsy
Calcium channel, voltage-dependent, alpha-2/delta-2 (isoform a)Q9NY47
Epilepsy
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (isoform 1)P54750
Epilepsy
Cholesterol 24-hydroxylaseQ9Y6A2
Epilepsy
Corticotropin-releasing factor receptor 1 isoform 1 precursorP34998
Epilepsy
Corticotropin-releasing factor receptor 1 precursor (isoform 2)P34998
Epilepsy
D(1B) dopamine receptorP21918
Epilepsy
Excitatory amino acid transporter 2 isoform 2P43004
Epilepsy
Galanin receptor (nonspecified subtype)
Epilepsy
Galanin receptor type 2O43603
Epilepsy
GalaninP22466
Epilepsy
Gamma-aminobutyric acid (GABA) A receptor beta 2 (isoform 1)P47870
Epilepsy
Gamma-aminobutyric acid (GABA) A receptor subunit alpha-3P34903
Epilepsy
Gamma-aminobutyric acid receptor subunit alpha-4P48169
Epilepsy
Gamma-aminobutyric acid receptor subunit beta-2 precursor (isoform 2)P47870
Epilepsy
Glutamate receptor ionotropic, kainate 1 (isoform 1)P39086
Epilepsy
Glutamate receptor ionotropic, kainate 2 (isoform 1)Q13002
Epilepsy
Glutamate receptor ionotropic, kainate 2 (isoform 3)Q13002
Epilepsy
Glutamate receptor ionotropic, kainate 3Q13003
Epilepsy
Glutamate receptor ionotropic, NMDA 2CQ14957
Epilepsy
Glutamate receptor ionotropic, NMDA 2DO15399
Epilepsy
HCN (nonspecified subtype)
Epilepsy
Kynurenine 3-monooxygenaseO15229
Epilepsy
Metabotropic glutamate receptor 7 precursor (isoform a)Q14831
Epilepsy
Metabotropic glutamate receptor 7 precursor (isoform b)Q14831
Epilepsy
Metabotropic glutamate receptor 8 precursor (isoform a)O00222
Epilepsy
P2X purinoceptor 3P56373
Epilepsy
Potassium voltage-gated channel subfamily A member 1Q09470
Epilepsy
Potassium voltage-gated channel subfamily KQT member 2 (isoform c)O43526
Epilepsy
Potassium voltage-gated channel subfamily KQT member 2 (isoform d)O43526
Epilepsy
Potassium voltage-gated channel subfamily KQT member 4P56696
Epilepsy
Serine racemaseQ9GZT4
Epilepsy
Small conductance calcium-activated potassium channel protein 1Q92952
Epilepsy
Small conductance calcium-activated potassium channel protein 2 (isoform a)Q9H2S1
Epilepsy
Sodium- and chloride-dependent betaine transporterP48065
Epilepsy
Sodium- and chloride-dependent GABA transporter 1P30531
EpilepsyMalaria
Sodium- and chloride-dependent GABA transporter 2 (isoform 1)Q9NSD5
Epilepsy
Sodium- and chloride-dependent GABA transporter 3P48066
Epilepsy
Sodium- and chloride-dependent glycine transporter 1 (isoform 2)P48067
Epilepsy
Sodium- and chloride-dependent glycine transporter 2Q9Y345
Epilepsy
Malaria
Sodium channel protein type 10 subunit alpha (Nav1.8) isoform 2Q9Y5Y9
Epilepsy
Sodium channel protein type 10 subunit alpha (Nav1.8)Q9Y5Y9
Epilepsy
Sodium channel protein type 2 subunit alpha (Nav1.2) (isoform 2)Q99250
Epilepsy
Sodium channel protein type 3 subunit alpha (Nav1.3 (isoform 2)Q9NY46
Epilepsy
Sodium channel protein type 3 subunit alpha (Nav1.3) (alternative isoform)Q9NY46
Epilepsy
Sodium channel protein type 3 subunit alpha (Nav1.3) (isoform 1)Q9NY46
Epilepsy
Sodium channel protein type 3 subunit alpha (Nav1.3) (isoform 3)Q9NY46
Epilepsy
Sodium channel protein type 4 subunit alpha (Nav1.4)P35499
Epilepsy
Sodium channel protein type 8 subunit alpha (Nav1.6) (isoform 1)Q9UQD0
Epilepsy
Solute carrier family 12, (potassium-chloride transporter) member 5Q9H2X9
Epilepsy
Synaptic vesicle glycoprotein 2A (isoform 1)Q7L0J3
Epilepsy
Synaptic vesicle glycoprotein 2A (isoform 2)Q7L0J3
Epilepsy
Synaptic vesicle glycoprotein 2C (isoform 1)Q496J9
Epilepsy
Synaptic vesicle glycoprotein 2C (isoform 2)Q496J9
Epilepsy
Thyrotropin-releasing hormone receptorP34981
Epilepsy
Transient receptor potential cation channel, subfamily C, member 5Q9UL62
Epilepsy
TransthyretinP02766
Epilepsy
Voltage-dependent calcium channel alpha-2/delta-1 subunitP54289
Epilepsy
Voltage-dependent R-type calcium channel subunit alpha-1E isoform 3Q15878
Epilepsy
Beta-hydroxyacyl-ACP dehydratase precursorQ8I6T4
Leishmaniasis
Malaria
Carbonic anhydraseQ9KMP6
Leishmaniasis
Casein kinase 1 (isoform 2)Q9NHE1
Leishmaniasis
Cysteine proteinase BP36400
Leishmaniasis
Enoyl-acyl carrier reductaseQ9BH77
Leishmaniasis
Malaria
Glyceraldehyde-3-phosphate dehydrogenaseQ38AR9
Leishmaniasis
Nicotinic alpha3beta4 Receptor
Leishmaniasis
N-Myristoyltransferase (protozoal)
LeishmaniasisMalaria
N-Myristoyltransferase 1 (NMT1) (protozoal)
Leishmaniasis
Malaria
Ornithine decarboxylase, putativeE9BAY5
Leishmaniasis
Protein ATP1B4Q9UN42
Leishmaniasis
Purine nucleosidase (nonspecified trypanosoma)
Leishmaniasis
Putative cathepsin L-like proteaseE9AMH7
Leishmaniasis
Serine Protease (protozoal)
MalariaLeishmaniasis
Sterol 24-C-Methyltransferase (Bacterial)
Leishmaniasis
Sterol 24-C-Methyltransferase (Fungal)
Leishmaniasis
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putativeQ8I273
Malaria
50S Ribosomal protein
Malaria
Adenosine deaminase, putativeQ8IJA9
Malaria
Botulinum neurotoxin type AA5HZZ9
Malaria
Calcium-dependent protein kinase 1P62344
Malaria
Calcium-dependent protein kinase CDPK1S7UHK8
Malaria
cGMP-dependent protein kinaseQ8I719
Malaria
CruzipainQ4DW02
Malaria
Cytochrome bQ02768
Malaria
Dihydroorotate dehydrogenase (Plasmodium falciparum)Q08210
Malaria
Elongation factor 2Q8IKW5
Malaria
Falcipain-3Q8IIL0
Malaria
Geranylgeranyl Pyrophosphate Synthase
Malaria
Hypoxanthine-guanine phosphoribosyltransferaseP20035
Malaria
Kinesin-5, putativeA0A060RSU4
Malaria
M1-family aminopeptidaseQ8IEK1
Malaria
Merozoite surface protein 1P04933
Malaria
Merozoite surface protein 3Q8IJ55
Malaria
Methionine aminopeptidase (bacterial)
Malaria
N-Myristoyltransferase 2 (NMT2) (protozoal)
Malaria
Non-SERCA-type Ca2+ -transporting P-ATPaseQ8I5T3
Malaria
Pannexin-1Q96RD7
Malaria
Cathepsin B-like cysteine proteinaseP25792
P32070
Schistosomiasis

  • Diabetes

    According to the World Health Organization, diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys, and nerves. It affects approximately 422 mln people worldwide with about 1.5 mln deaths directly attributed to diabetes each year. In the framework of our project we will study the most acute problems associated with diabetes treatment in close collaboration with medical doctors from Department of Endocrinology of Osmania General Hospital and Osmania Medical College, Hyderabad, India.


    Leishmaniasis

    According to the World Health Organization, there are 3 main forms of leishmaniases – visceral (the most serious), cutaneous (the most common), and mucocutaneous. Leishmaniasis is caused by the protozoan Leishmania parasites which are transmitted by the bite of infected female phlebotomine sandflies. In the framework of our project we will investigate the existing targets for antileishmanial drugs, and try to identify the novel promising targets and their ligands that may improve the curation of the disease.


    Cancer

    According to the World Health Organization, cancers (malignant tumors, neoplasms) are one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths. Cancer is a generic term for a large group of diseases with a complex etiology. In the framework of our project we will focus on a breast cancer, particularly on a triple negative form, which is not associated with the estrogen and progesterone hormones, or with the presence of too many HER2 receptors. In addition to design of antineoplastic compounds active against triple negative breast cancer (TNBC), we will try to identify the inhibitors of heat shock protein 70, which is overexpressed in breast cancer (Jagadish N. et al., 2016. DOI: 10.1186/s13046-016-0425-9). Ideally, the desired pharmaceutical agents have to combine the multitarget inhibitory activity on TNBC and Hsp70.

  • Tuberculosis

    Tuberculosis (TB), is a common and potentially deadly infectious disease caused by species and subspecies of the Myocobacterium tuberculosis complex, primarily Mycobacterium tuberculosis. According to the World Health Organization, in 2015 there were about 10.4 mln new (incident) TB cases worldwide, including 480000 new cases of multidrug-resistant TB (MDR-TB) and an additional 100000 people with rifampicin-resistant TB (RR-TB) who were also newly eligible for MDR-TB treatment. In the framework of our project we will focus on identification of molecular targets and their combinations, action on which may be the most promising for treatment of MDR-TB.


    Malaria

    According to the World Health Organization, malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2015 malaria affects approximately 212 mln people with 429000 deaths. In the framework of our project we will investigate the existing targets for antimalarial drugs, and try to identify the novel promising targets and their ligands that may improve the prevention and curation of the disease.


    Epilepsy

    According to the World Health Organization, epilepsy is a chronic noncommunicable illness of the brain that affects about 50 million people of all ages worldwide. Nearly 80% of the people with epilepsy live in low- and middle-income countries, and about three fourths of those people do not get the treatment they need. In the context of our project, we will focus on refractory (pharmacoresistant) epilepsy, which affect about 30% of epileptic patients, who may suffer from irreversible disabilities and pre-mature deaths. The mechanisms of refractory epilepsy are still unclear; however, many efforts are ongoing into discovery and development of novel antiepileptic agents with better therapeutic profiles. Better understanding of the heterogeneous nature of epilepsy and the multiple complex factors, which contribute to the abnormal neural discharges, will create the basis for progress in development of etiological rather than symptomatic therapies.